OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Vaccine-induced memory	1034
Pathogenic T cells in post-viral lung disease in mice	835
The delivery device of SARS-CoV-2 mucosal vaccine matters	701
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	528
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	471
Charting granulopoietic disturbances in sepsis	464
Ironman training for NK cells	460
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	376
Complement profile	357
Imprinting tissue immunity	353
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	322
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	321
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	298
Keeping neonatal intestines happy	272
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	259
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	227
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat	201
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	193
The complexity of immune evasion mechanisms throughout the metastatic cascade	186
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	172
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	169
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	169
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	168
Lactation-associated macrophages exist in murine mammary tissue and human milk	166
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	165

Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	164
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	161
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	157
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	154
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	152
CTLA-4 tail fusion enhances CAR-T antitumor immunity	150
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	147
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	146
Defective fibrinolysis in periodontitis	145
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	143
KEAP1 maintains stemness	139
Reversing T cell immunity reveals the basis for T cell lineage fate determination	138
Nociceptors enhance humoral immunity	137
Restriction factor	137
Illuminating the nervous system to treat colitis	135
A polarizing answer — microglia in Nasu-Hakola disease	134
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	132
CAR macrophages on a fast track to solid tumor therapy	132
G-CSF drives autoinflammation in APLAID	132
A microbial iron fist to fight tumors	131
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	131
The road not taken en route to T cell exhaustion	130
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	129
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	128
Enhancing T cell therapy	127
Insights into autoimmunity and cancer	125
m1A tRNA modification facilitates rapid T cell proliferation	124
Learning from inborn errors	123
Aging lymph node responses	122
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	121
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	121
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	120
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	119
JAK-STAT signaling maintains homeostasis in T cells and macrophages	118
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells	116
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	115
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	115
Aging disrupts circadian gene regulation and function in macrophages	115
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines	112
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	108
Defining macrophages in the lactating murine mammary gland and human milk	107
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	107
Mucus needs GSDMD	106
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection	105
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation	105
Prenatal and postnatal neuroimmune interactions in neurodevelopmental disorders	104
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection	104
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers	103
Depletion of slow-cycling PDGFRα+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis	102
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms	99

Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells	97
Low-avidity T cells drive endogenous tumor immunity in mice and humans	95
Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature	94
Transcriptional state and function of CD8+ memory T cells is linked to past proliferation	93
What Jane Jacobs has taught me about neuroimmunology	91
Three cytokine pairs modulate sepsis effects at the organism level	90
Less BMI-1 is more for chronic infections	88
Role of the T cell vitamin D receptor in severe COVID-19	87
Reply to ‘Comment on: Repositioning TH cell polarization from single cytokines to complex help’	86
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	86