OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 87. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Vaccine-induced memory	1107
The delivery device of SARS-CoV-2 mucosal vaccine matters	1040
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	782
Ironman training for NK cells	624
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	563
Keeping neonatal intestines happy	526
Charting granulopoietic disturbances in sepsis	519
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	440
Imprinting tissue immunity	395
Complement profile	384
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	257
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	235
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	227
TFH cell programs by pathogen and species	227
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	215
Secretogranin 2 binds LILRB4 resulting in immunosuppression	211
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	209
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	205
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	202
A little less reading, a little more type 9 action	197
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	195
Pathogenic T cells in post-viral lung disease in mice	186
Neurons protect against fibrosis	185
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	183
Astrocyte TRAIL promotes GBM	182

Lactation-associated macrophages exist in murine mammary tissue and human milk	178
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	175
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	171
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	170
CTLA-4 tail fusion enhances CAR-T antitumor immunity	168
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	166
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	166
The complexity of immune evasion mechanisms throughout the metastatic cascade	165
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	162
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	162
Nociceptors enhance humoral immunity	161
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	161
Restriction factor	158
Reversing T cell immunity reveals the basis for T cell lineage fate determination	156
m1A tRNA modification facilitates rapid T cell proliferation	154
Enhancing T cell therapy	152
Insights into autoimmunity and cancer	150
Aging lymph node responses	148
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis	147
Six degrees of TGFβ	147
Defective fibrinolysis in periodontitis	145
The road not taken en route to T cell exhaustion	143
A microbial iron fist to fight tumors	143
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	142
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	139
Microglia loss triggers glial stress and white matter damage in human leukodystrophy	134
Learning from inborn errors	132
Carboxylation switch	131
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription	129
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	128
CAR macrophages on a fast track to solid tumor therapy	126
Beneficial role of GZMK+CD8+ T cells in neurodegeneration	125
Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt	120
KEAP1 maintains stemness	117
A polarizing answer — microglia in Nasu-Hakola disease	114
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	113
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	112
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	112
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity	111
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	108
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	108
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines	104
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells	103
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	103
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	101
JAK-STAT signaling maintains homeostasis in T cells and macrophages	99
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	99
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	99
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	99
G-CSF drives autoinflammation in APLAID	98

Aging disrupts circadian gene regulation and function in macrophages	95
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	94
The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets	93
Defining macrophages in the lactating murine mammary gland and human milk	93
Mucus needs GSDMD	93
LPS structure shapes Treg cells	93
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms	91
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	91
2B or not 2B is the question in DC ontogeny	91
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	89
Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells	88
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation	88