Current Treatment Options in Oncology

Article	Citations
Role of Metastasis-Directed Therapy in Genitourinary Cancers	123
Correction to: Antibody–Drug Conjugate Revolution in Breast Cancer: The Road Ahead	91
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer	86
Antibody-Drug Conjugates for Melanoma and Other Skin Malignancies	81
“Off-the-Shelf” Allogeneic CAR Cell Therapy—Neglected HvG Effect	67
Current Approaches of Immune Checkpoint Therapy in Chronic Lymphocytic Leukemia	60
Clinical Application of Artificial Intelligence for Non-melanoma Skin Cancer	60
Advances in the Pathogenesis, Diagnosis, Treatment, and Prognosis of Marginal Zone Lymphoma	57
Current Therapeutic Landscape in Lower Risk Myelodysplastic Syndromes	56
The Future of Natural Killer Cell Immunotherapy for B Cell Non-Hodgkin Lymphoma (B Cell NHL)	50
An Update on Temporal Bone Paragangliomas	48
Small Cell Lung Cancer—An Update on Chemotherapy Resistance	48
Chronic Lymphocytic Leukemia: Chemotherapy Free and Other Novel Therapies Including CAR T	44
HPV as a Carcinomic Driver in Head and Neck Cancer: a De-escalated Future?	42
Options and Considerations in the Management of Peritoneal Disease in Patients with Small Bowel Neuroendocrine Tumors	39
Combining Radiotherapy with Immunotherapy in Cervical Cancer: Where Do We Stand and Where Are We Going?	39
Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers	38
The Role of Nursing in the Delivery of Cardio-Oncology	37
Depression and Long-Term Prescription Opioid Use and Opioid Use Disorder: Implications for Pain Management in Cancer	36
Recent Advances in Liver Transplantation for Hepatocellular Carcinoma	34
Approach to Localized Squamous Cell Cancer of the Esophagus	33
Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities	32
Management of Fatigue in Patients with Advanced Cancer	32
Regorafenib for the Treatment of Sarcoma	31
Targets Selection for Precision Therapy of Relapsed/Refractory Multiple Myeloma: the Latest Advancements	31

Revolutionizing Breast Cancer Therapeutics: Intersecting Frontiers of Precision Medicine, Nanotechnology, and Drug Delivery Innovations	30
Where Are We Now and Where Might We Be Headed in Understanding and Managing Brain Metastases in Colorectal Cancer Patients?	30
Reshaping Treatment Paradigms for Advanced Renal Cell Cancer Patients and Improving Patient Management	28
The Review of Modified Intersphincteric Resection in the Treatment of Ultra-Low Rectal Cancer	27
Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer	27
Advances in Targeted Therapy for Metastatic Prostate Cancer	27
Proposals for Clinical Trials in Chronic Myelomonocytic Leukemia	26
Novel Approaches for the Treatment of Patients with Richter’s Syndrome	26
Optimal Strategies for Colorectal Cancer Screening	25
New Treatment Options for Newly-Diagnosed and Relapsed Chronic Lymphocytic Leukemia	25
Circulating Tumor DNA in Diffuse Large B-Cell Lymphoma: from Bench to Bedside?	24
Recognition and Management of the Long-term Effects of Cranial Radiation	24
Essential Thrombocythemia in Adolescents and Young Adults: Clinical Aspects, Treatment Options and Unmet Medical Needs	23
Steroid Premedication and Monoclonal Antibody Therapy: Should We Reconsider?	23
A Comprehensive Review on the Role of Lurbinectedin in Soft Tissue Sarcomas	22
Treatment Options for Brain Metastases	22
Gastric Cancer with Sarcopenia: an Area Worth Focusing On	22
Correction to: The Microbiome: the Link to Colorectal Cancer and Research Opportunities	22
Promising Blood-Based Biomarkers for Melanoma: Recent Progress of Liquid Biopsy and Its Future Perspectives	21
Contemporary Review of Adenocarcinoma of the Cervix	21
Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment	21
Therapeutic Challenges in the Management of Serous Endometrial Intraepithelial Carcinoma (SEIC)	21
Novel Estrogen Receptor-Targeted Agents for Breast Cancer	21
Dyadic Interventions for LGBTQ+ Individuals Facing Cancer: A Narrative Review	21
Evolution of Treatment Strategies for Gestational Trophoblastic Neoplasia: Chemotherapy, Immunotherapy, and Molecular Targeted Therapy	20
New Therapeutic Targets in RAS Wild-type Pancreatic Cancer	20
Response Evaluation of Neoadjuvant Therapies in Sarcoma	20
R0 Resection in Recurrent Gynecologic Malignancy: Pelvic Exenteration and Beyond	20
Emerging DNA Methylome Targets in FLT3-ITD-Positive Acute Myeloid Leukemia: Combination Therapy with Clinically Approved FLT3 Inhibitors	19
Approach to Stereotactic Body Radiotherapy for the Treatment of Advanced Hepatocellular Carcinoma in Patients with Child-Pugh B-7 Cirrhosis	19
Neoadjuvant Photodynamic Therapy: An Updated Therapeutic Approach for Non-Melanoma Skin Cancers	19
New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms	19
Research Progress on Ferroptosis in Multiple Myeloma	19
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities	19
Neoadjuvant and Adjuvant Therapy Approaches to Gastric Cancer	19
Current Trends in Precision Medicine and Next-Generation Sequencing in Head and Neck Cancer	19
One Size Fits Some: Approaching Rare Malignancies of the Urinary Tract	19
Updates in Breast Cancer Screening and Diagnosis	18
The Dilemma of Treating Delirium: the Conundrum of Drug Management	18
New Developments in Systemic Management for High-Risk Early-Stage Hormone-Receptor-Positive, HER2-Negative Breast Cancer	18
Updates in Management of Malignant Pleural Mesothelioma	18
Navigating PARP Inhibitor Resistance in Ovarian Cancer: Bridging Mechanistic Insights To Clinical Translation	17
How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia	17
Advancing Bladder Cancer Management: The Role of Neoadjuvant and Adjuvant Therapies and Biomarkers in Muscle Invasive Bladder Cancer	17
What are the Optimal Systemic Treatment Options for Rhabdomyosarcoma?	17
Progress in the Treatment of Small Intestine Cancer	17
Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations	16
Perioperative Immune Checkpoint Inhibitors for the Treatment of Locally Advanced Gastric and Gastroesophageal Junction Cancer: Current Status and Future Prospects	16
New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease	16
Immunotherapy in the Treatment of Undifferentiated Pleomorphic Sarcoma and Myxofibrosarcoma	16

Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer: Lessons Learned and Future Perspectives	16
Correction to: Cardiotoxicity of Systemic Melanoma Treatments	15
The Role of SIRT1 in Leukemia	15
“When Less is More”: Paradigm Shifts in Radiation Treatment for Early-Stage Breast Cancer	15
Optimal First-Line Therapy for Metastatic Adenocarcinoma of the Esophagus	15
Re-thinking the Role of Thoracic Radiotherapy in the First-Line Treatment for Extensive-Stage Small Cell Lung Cancer	15
Myxoid Liposarcomas: Systemic Treatment Options	15
Taxane-Associated Acute Pain Syndrome: a Review of its Features and Management	14
Metastatic Castration-Resistant Prostate Cancer: Advances in Treatment and Symptom Management	14
Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy	14
Management and Treatment of Non-small Cell Lung Cancer with MET Alteration and Mechanisms of Resistance	14
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?	14
The Role of Induction Therapy for Sinonasal Cancers	14
New Developments in Treating RAS-Mutated Metastatic Colorectal Cancer	14
Targeting the Renin–angiotensin–aldosterone System (RAAS) for Cardiovascular Protection and Enhanced Oncological Outcomes: Review	14
Advances in PSMA-Targeted Radionuclide Therapeutics	14
Complex Persistent Opioid Dependence—an Opioid-induced Chronic Pain Syndrome	14
A Review on Integrating Breast Cancer Clinical Data: A Unified Platform Perspective	14
HER2-Positive Metastatic Colorectal Cancer	13
Correction to: Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies	13
Emerging Therapeutic Approaches to Pancreatic Adenocarcinoma: Advances and Future Directions	13
RAS and Other Molecular Targets in Pancreatic Cancer: The Next Wave Is Coming	13
Correction to: Voluntary Assisted Dying/Euthanasia: Will This Have an Impact on Cancer Care in Future Years?	13
ctDNA to Guide Treatment of Colorectal Cancer: Ready for Standard of Care?	13
Dermatofibrosarcoma Protuberans (DFSP): Diagnostics and Molecular Pathology	13
Management of Functional Pancreatic Neuroendocrine Neoplasms	13
Advancements in Melanoma Therapies: From Surgery to Immunotherapy	13
The Use of Targeted Agents in the Treatment of Gynecologic Cancers	13
Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors	13
Impact of PSMA PET on Prostate Cancer Management	12
Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches	12
Radiotherapy for Advanced Esophageal Cancer: from Palliation to Curation	12
Neuroendocrine Tumors: Germline Genetics and Hereditary Syndromes	12
Therapeutic Management of Malignant Wounds: An Update	12
The Role of Pharmacogenomics in Opioid Prescribing	12
Targeted Therapy in Early Stage Non-small Cell Lung Cancer	12
Correction to: Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer	12
The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy	12
Systemic and Targeted Therapies in Adenoid Cystic Carcinoma	11
Osteogenic Sarcoma of the Head and Neck: Is Chemotherapy Needed?	11
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer	11
Community Palliative Care: What are the Best Models?	11
Management of Stage IVB Cervical Cancer Including the Role of Radiotherapy	11
Diagnosis and Treatment of Myxoid Liposarcoma	11
Measurable Residual Disease in Chronic Lymphocytic Leukemia: Current Understanding and Evolving Role in Clinical Practice	11
Innovations in Cardio-oncology Resulting from the COVID-19 Pandemic	11
Integrating Systemic Therapies into the Multimodality Therapy of Patients with Craniopharyngioma	11
Current WHO Guidelines and the Critical Role of Genetic Parameters in the Classification of Glioma: Opportunities for Immunotherapy	11
What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?	11
Systemic Management of Advanced Adrenocortical Carcinoma	11
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery	11
Is There Still a Role for Transplant for Patients with Mantle Cell Lymphoma (MCL) in the Era of CAR-T Cell Therapy?	11
Cardio-Oncology Care Delivered in the Non-academic Environment	11
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment	11
Dermatofibrosarcoma Protuberans (DFSP): Current Treatments and Clinical Trials	10
Neuropathic Pain in Cancer: What Are the Current Guidelines?	10
Role of Geriatric Assessment in Hematopoietic Stem Cell Transplant and Cellular Therapies	10
Treatment of Relapsed Acute Lymphocytic Leukemia in Adult Patients	10
Current Surgical Management for Acral Melanoma	10
Advanced Acral Melanoma Therapies: Current Status and Future Directions	10
Central Nervous System Prophylaxis and Treatment in Acute Leukemias	10
Antibody-Drug Conjugates in Gynecologic Cancers	10
Induction Chemotherapy in Low-Risk HPV+ Oropharyngeal Cancer	10
Management of Cutaneous Angiosarcoma: an Update Review	10
An Update on the Clinical Status, Challenges, and Future Directions of Oncolytic Virotherapy for Malignant Gliomas	10
The Role of Sentinel Lymph Node Mapping in High-grade Endometrial Cancer	10
Radiation and Chimeric Antigen Receptor T-cell Therapy in B-cell Non-Hodgkin Lymphomas	10
Central Nervous System Metastases in Breast Cancer	10
Prediction of Response to FDA-Approved Targeted Therapy and Immunotherapy in Acute Lymphoblastic Leukemia (ALL)	10
Gastrointestinal Stromal Tumors: What Is the Best Sequence of TKIs?	9
The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies	9
Advances in Understanding Drug Resistance Mechanisms and Innovative Clinical Treatments for Melanoma	9
Evolving Immunotherapy Strategies in Gastrointestinal Neuroendocrine Neoplasms	9
Skin Reactions and Other Underappreciated Dermatologic Side Effects of Cancer Therapies	9
New Molecular Insights, and the Role of Systemic Therapies and Collaboration for Treatment of Epithelioid Hemangioendothelioma (EHE)	9
Relapsed Synovial Sarcoma: Treatment Options	9
Contemporary Use of Hormonal Therapy in Endometrial Cancer: a Literature Review	9
The Crying Need for a Better Response Assessment in Rectal Cancer	9
Immunotherapy in Early-Stage Triple-Negative Breast Cancer: Where Are We Now and Where Are We Headed?	9
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review	9

The Microbiome: the Link to Colorectal Cancer and Research Opportunities	9
Interventional Cardio-Oncology: Unique Challenges and Considerations in a High-Risk Population	9
Current Drug Resistance Mechanisms and Treatment Options in Gastrointestinal Stromal Tumors: Summary and Update	9
The Evolving Treatment Landscape of Merkel Cell Carcinoma	9
Secondary Central Nervous System Lymphoma: Updates in Treatment and Prophylaxis Strategies	9
Correction to: Metastatic Hormone–Sensitive Prostate Cancer in the Era of Doublet and Triplet Therapy	9
A Comprehensive Review of Cancer Drug–Induced Cardiotoxicity in Blood Cancer Patients: Current Perspectives and Therapeutic Strategies	8
Addressing Sexual Health in Breast Cancer Survivors: Evidence-Based Practices and Clinical Considerations	8
Combination Immunotherapy for Mucosal Melanoma: Molecular Mechanism, Research Status, and Future Directions	8
Covalent and Non-Covalent BTK Inhibition in Chronic Lymphocytic Leukemia Treatment	8
Underlying Mechanisms of Thrombosis Associated with Cancer and Anticancer Therapies	8
Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence	8
Frontiers of Ovarian Carcinosarcoma	8
Angiosarcoma: Role of Immunotherapy	8
PAI-1 in Skin Malignancies: a Central Regulator of Tumor Progression and Therapeutic Resistance	8
Not All Leiomyosarcomas Are the Same: How to Best Classify LMS	8
New Immuno-oncology Targets and Resistance Mechanisms	8
Updates in Systemic Treatment of Hormone Receptor-Positive Early-Stage Breast Cancer	8
The Evolving Neoadjuvant Treatment Paradigm for Patients with Locoregional mismatch Repair Proficient Rectal Cancer	8
Tarlatamab-dlle: A New Hope for Patients with Extensive-Stage Small-Cell Lung Cancer	8
Candidate Biomarker of Response to Immunotherapy In Small Cell Lung Cancer	8
Systemic Anticancer Treatment Near the End of Life: a Narrative Literature Review	7
Molecular Secrets Revealed: How Diabetes may be Paving the Way for Leukemia	7
Cardio-oncology for Pediatric and Adolescent/Young Adult Patients	7
Immune Checkpoint Inhibitors for the Treatment of Gestational Trophoblastic Neoplasia: Rationale, Effectiveness, and Future Fertility	7
Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia	7
Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer	7
Updates on Therapy Options in Fit and Unfit Patients with Newly Diagnosed AML	7
Epithelioid Hemangioendothelioma: Treatment Landscape and Innovations for an Ultra-Rare Sarcoma	7
Targeted Therapies in the Treatment of Uterine Serous Carcinoma	7
Immunotherapy in HPV-Related Oropharyngeal Cancers	7
Pathogenic Mechanisms in Acute Myeloid Leukemia	7
Metastatic HER2-Positive Breast Cancer: Is There an Optimal Sequence of Therapy?	7
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?	7
Dermatofibrosarcoma Protuberans in Children	7
Natural Killer Cells: the Missing Link in Effective Treatment for High-Grade Serous Ovarian Carcinoma	7
Neoadjuvant Short- Vs. Long-Course Radiation for Locally Advanced Rectal Cancer: How to Choose	7
Treatment of node-positive endometrial cancer: chemotherapy, radiation, immunotherapy, and targeted therapy	7
State of the Art in Endoscopic Therapy for the Management of Gastroenteropancreatic Neuroendocrine Tumors	7
Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers	7
Incorporating Molecular Diagnostics into Treatment Paradigms for Endometrial Cancer	7
Papillary Renal Cell Carcinoma: A Review of Prospective Clinical Trials	7
Desmoid Tumors: Current Perspective and Treatment	7
Current Standards, Multidisciplinary Approaches, and Future Directions in the Management of Extrahepatic Cholangiocarcinoma	7
Surgery Matters: Progress in Surgical Management of Gastric Cancer	7
What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?	6
Cardio-Oncology and Breast Cancer Therapies	6
Photodynamic application in diagnostic procedures and treatment of non-melanoma skin cancers	6
Current Treatment Options for Cutaneous Adnexal Malignancies	6
Molecular Heterogeneity in Leiomyosarcoma and Implications for Personalised Medicine	6
Treatment Strategies for Malignancies of the External Auditory Canal	6
Emerging Advances in the Molecular Landscape of Penile Cancer and Their Implications for Precision Medicine	6
Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective	6
Correction to: Cancer-Related Fatigue: Causes and Current Treatment Options	6
Targeted Therapy and Immunotherapy in Elderly Patients with Metastatic Colorectal Cancer	6
In Utero Development and Immunosurveillance of B Cell Acute Lymphoblastic Leukemia	6
Therapeutic and Supportive Effects of Cannabinoids in Patients with Brain Tumors (CBD Oil and Cannabis)	6
Beyond Serous: Treatment Options for Rare Endometrial Cancers	6
Do Patients Benefit from a Trial of Corticosteroids at the End of Life?	6
Surgery in Patients with Gastro-Entero-Pancreatic Neuroendocrine Carcinomas, Neuroendocrine Tumors G3 and High Grade Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms	6
Advances in the Treatment of Hairy Cell Leukemia Variant	6
How the COVID-19 Pandemic Reshaped the Management of Leukemia and Affected Patient Outcomes	6
Research Progress on the Use of Metformin in Leukemia Treatment	6
Targeting the FGFR Pathway in Urothelial Carcinoma: the Future Is Now	6
Intraperitoneal and Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Ovarian Cancer	6
Advances in Surgical Management of Malignant Tumors of the Distal Tibia	6
CDK4/6 Inhibition in the Metastatic Setting: Where Are We Headed?	6
The Role of Radiotherapy in the Management of Melanoma Brain Metastases: An Overview	6
Respiratory Depression Associated with Opioids: A Narrative Review	6
Neoadjuvant Chemotherapy for Adults with Osteogenic Sarcoma	6
High-Dose Somatostatin Analogs for the Treatment of Neuroendocrine Neoplasms: where are we Now?	6