OOIR: Observatory of International Research

Papers

(The median citation count of Nucleosides Nucleotides & Nucleic Acids is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Synthesis, characterization, ADMET, in vitroandin vivo studies of mixed ligand metal complexes from a curcumin Schiff base and lawsone	26
In silico strategies for modeling RNA aptamers and predicting binding sites of their molecular targets	19
Determination of total purine and purine base content of 80 food products to aid nutritional therapy for gout and hyperuricemia	17
COVID-19 may enhance risk of thrombosis and hemolysis in the G6PD deficient patients	16
Synthesis of new uracil derivatives and their sugar hydrazones with potent antimicrobial, antioxidant and anticancer activities	15
Synthesis, anticancer activity and molecular docking of new triazolo[4,5-d]pyrimidines based thienopyrimidine system and their derived N-glycosides and thioglycosides	15
Design, synthesis, chemical characterization, biological evaluation, and docking study of new 1,3,4-oxadiazole homonucleoside analogs	14
Design, synthesis and anticancer activity of novel pyrimidine and pyrimidine-thiadiazole hybrid glycosides	13
Relationship between miR-143/145 cluster variations and cancer risk: proof from a Meta-analysis	13
Synthesis, antimicrobial, SAR, PASS, molecular docking, molecular dynamics and pharmacokinetics studies of 5′-O-uridine derivatives bearing acyl moieties: POM study and identification of the ph	10
Efficient one-pot, three-component procedure to prepare new α-aminophosphonate and phosphonic acid acyclic nucleosides	10
Problems associated with antiviral drugs and vaccines development for COVID-19: approach to intervention using expression vectors via GPI anchor	9
Huntingtin protein maintains balanced energetics in mouse cardiomyocytes	9
Synthesis of novel pyrimidine thioglycosides as structural analogs of favipiravir (avigan) and their antibird flu virus activity	9
The influence of quality of primers on the formation of primer dimers in PCR	9
Synthesis, antitubercular activity and molecular docking study of substituted [1,3]dioxino[4,5-d]pyrimidine derivatives via facile CAN catalyzed Biginelli reaction	8
Long noncoding RNA HOTAIR polymorphisms and susceptibility to bipolar disorder: a preliminary case–control study	8
Synthesis, characterization, and DNA binding study of ruthenium(II/III) complexes containing ONS donor Schiff base	8
Containing the spread of COVID-19 virus facing to its high mutation rate: approach to intervention using a nonspecific way of blocking its entry into the cells	8
Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2	7
Anti-proliferative, apoptotic potential of synthesized selenium nanoparticles against breast cancer cell line (MCF7)	7
Recent updates on purine and pyrimidine metabolism in physiological and pathological settings	7
Transcriptome-based identification of molecular markers related to the development and prognosis of Colon cancer	7
In vitro spectroscopic investigation of groove binding interaction of Fe₃O₄@CaAl-LDH@L-Dopa with calf thymus DNA	7
Lesch-Nyhan disease: I. Construction of expression vectors for hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme and amyloid precursor protein (APP)	7

Measurement of the total purine contents and free nucleosides, nucleotides, and purine bases composition in Japanese anchovies (Engraulis japonicus) using high-performance liquid chromatography	6
50-bp insertion/deletion polymorphism of the superoxide dismutase-1 is associated with bladder cancer risk in an Iranian population	6
Refractory gout – does it exist?	6
Design and synthesis of a new class of indeno[1,2-b]pyridine thioglycosides	6
Hereditary disease prediction in eukaryotic DNA: an adaptive signal processing approach	6
Association of common genetic variants of KCNJ11 gene with the risk of type 2 diabetes mellitus	6
HMGA2 rs968697 T > C polymorphism is associated with the risk of colorectal cancer	6
Modifications on the heterocyclic base of ganciclovir, penciclovir, acyclovir - syntheses and antiviral properties	6
Spectroscopic and docking molecular study of new anticancer Pt complex binding with human serum albumin	6
Identification of a novel thymidylate kinase activity	6
MicroRNA-30b participates in the pathological process of hyperuricemia by regulating interleukin-6 receptor	5
Purine analogs: synthesis, evaluation and molecular dynamics of pyrazolopyrimidines based benzothiazole as anticancer and antimicrobial CDK inhibitors	5
Lactobacillus gasseri PA-3 directly incorporates purine mononucleotides and utilizes them for growth	5
Cashew nutshell liquid catalyzed green chemistry approach for synthesis of a Schiff base and its divalent metal complexes: molecular docking and DNA reactivity	5
Toll-Like receptor 4 (TLR4) polymorphism rs2149356 and risk of gout in a Spanish cohort	5
Diabetic nephropathy produces alterations in the tissue expression profile of the orphan receptors GPR149, GPR153, GPR176, TAAR3, TAAR5 and TAAR9 in Wistar rats	5
In silico and POM analysis for potential antimicrobial agents of thymidine analogs by using molecular docking, molecular dynamics and ADMET profiling	5
Expression of the nucleoside transporters hENT1 (SLC29) and hCNT1 (SLC28) in pediatric acute myeloid leukemia	5
Association between common variants in vitamin D receptor gene and susceptibility to Non-Hodgkin’s lymphoma: a case-control study	5
Removal of 1,2-benzanthracene via the intercalation of 1,2-benzanthracene with DNA and magnetic bead-based separation	4
Synthesis, spectroscopic and biological activity evaluation of Ni(II), Cu(II) and Zn(II) complexes of schiff base derived from pyridoxal and 4-fluorobenzohydrazide	4
Purine analogues as potential CDK9 inhibitors: New pyrazolopyrimidines as anti-avian influenza virus	4
Synthesis, structural, pharmacological and molecular docking simulations studies of Schiff base transition metal complexes procured from acetylacetonyl-4-iminoantipyrine and tyrosine	4
Synthesis and applications of bicyclic sugar modified locked nucleic acids: A review	4
Methylene-tetrahydrofolate reductase gene C677T and A1298C polymorphisms as a risk factor for Crimean-Congo hemorrhagic fever	4
Lower vitamin D levels and VDR variants are risk factors for breast cancer: an updated meta-analysis	4
Silver(I)-mediated base pairing involving an S-glycosidic GNA nucleoside analogue	4
Synthesis, DNA binding and antimicrobial studies on rhodium(II) complexes of dicyandiamide	4
MicroRNA-183-5p regulates MITF expression in vitiligo skin depigmentation	4
Bright fluorescent purine analogues as promising probes	4
Missense, silent, non-sense and frame-shift mutations in exon 3 of the filaggrin gene in patients with bronchial asthma, atopic dermatitis, allergic rhinitis and mixed atopy	4
Multispectroscopic and molecular docking studies on DNA binding of guaifenesin drug	4
Long non-coding RNA AGAP2-AS1 is up regulated in colorectal cancer	4
Synthesis of novel pyridine and pyrimidine thioglycoside phosphoramidates for the treatment of COVID-19 and influenza A viruses	4
Bimodular thrombin aptamers with two types of non-covalent locks	4
Spectroscopic studies on the interaction of aspartame with human serum albumin	4
Single-stranded DNA versus tailed duplex in sequence conversion of lacZα DNA	4
CD123 thioaptamer protects against sepsis via the blockade between IL-3/CD123 in a cecal ligation and puncture rat model	4
Studies to explore the UVA photosensitizing action of 9-phenylacridine in cells by interaction with DNA	4
Electrical conductance measurement of Hg^II-mediated DNA duplex in buffered aqueous solution	3
Expression analysis of PINK1 and PINK1-AS in multiple sclerosis patients versus healthy subjects	3
Expression profiles of GPR21, GPR39, GPR135, and GPR153 orphan receptors in different cancers	3
Differential expression analysis of CCDC107 and RMRP lncRNA as potential biomarkers in colorectal cancer diagnosis	3
Comparison of plasma nucleotide metabolites and amino acids pattern in patients with binge eating disorder and obesity	3
Synthesis of 2′-deoxyguanosine from 2′-deoxyadenosine via C2 nitration	3
Synthesis of N-substituted morpholine nucleoside derivatives	3
The correlation of uric acid levels with biochemical parameters and dietary factors in individuals with asymptomatic hyperuricemia and gouty arthritis	3
Music alleviates pain perception in depression mouse models by promoting the release of glutamate in the hippocampus of mice to act on GRIK5	3
Synthesis, characterization, cytotoxicity and DNA/BSA binding of two amino acid palladium(II) complexes derived from alanine and valine	3
Ceruloplasmin inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells and is negatively regulated by miR-543	3

Exhaled breath condensate efficacy to identify mutations in patients with lung cancer: A pilot study	3
Some miRNA expressions and their targets in ischemic stroke	3
The effect of lactate dehydrogenase-A inhibition on intracellular nucleotides and mitochondrial respiration in pancreatic cancer cells	3
Association between HULC rs7763881 and cancer risk: an updated Meta-analysis	3
Effects of plants extracts on the expression of major genes of JAK/STAT pathway	3
Efficient implementation of parametric spectral estimation techniques for DNA exon prediction	3
6-Morpholino- and 6-amino-9-sulfonylpurine derivatives. Synthesis, computational analysis, and biological activity	3
Tetra-ARMS-PCR assay development for genotyping of AGT rs699 T/C polymorphism, its comparison with PCR-RFLP and application in a case-control association study of cardiovascular disease patient	3
Structural, molecular hybridization and network based identification of miR-373-3p and miR-520e-3p as regulators of NR4A2 human gene involved in neurodegeneration	3
Transcription of DNA duplex containing deoxypseudouridine and deoxypseudoisocytidine, and inhibition of transcription by triplex forming oligonucleotide that recognizes the modified duplex	2
Synthesis and base-pairing properties of pyrazine nucleic acids	2
Synthesis of molnupiravir (MK-4482, EIDD-2801): a promising oral drug for the treatment of COVID-19 starting from cytidine	2
The comparison of nucleotide metabolites and amino acids patterns in patients with eating disorders, with and without symptoms of depression	2
DNA binding ability and cytotoxicity, cell cycle arrest and apoptosis inducing properties of a benzochromene derivative against K562 human leukemia cells	2
Species-dependent patterns of incorporation of purine mononucleotides and nucleosides by lactic acid bacteria	2
In vitro interaction of nucleoside reverse transcriptase inhibitor, didanosine with calf-thymus DNA: Insights from spectroscopic studies	2
New insights in research on purine and pyrimidine metabolism	2
Design, synthesis and chemical stability of indolizine derivatives for antidiabetic activity	2
Exploring the binding characteristics of febuxostat, an inhibitor of xanthine oxidase with calf thymus DNA: Multi-spectroscopic methodologies and molecular docking	2
Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis	2
5-alkylvinyl-1,2,4-triazole nucleosides: Synthesis and biological evaluation	2
Fabrication, depiction, DNA interaction, anti-bacterial, DFT and molecular docking studies of Co(II) and Cu(II) complexes of 3-methyl-1-phenyl-4-[(E)-(pyridin-2-yl)diazenyl]-1H-pyrazol-5	2
The association of IGF1 rs35767 polymorphism with colorectal cancer risk in the Chinese Han population	2
Fluorescent DNA analog: 2-aminotroponyl-pyrrolyl-2’-deoxyuridinyl DNA oligo enhance fluorescence in DNA-duplex as compared to 2-aminotroponyl-ethynyl-2’-deoxyuridinyl DNA oligo	2
Unusual seven-membered ring sugars and nucleosides: synthesis and biological properties	2
Urate levels and clearance in renal patients under peritoneal dialysis	2
Association between the IL-1A, IL-1B and IL-1R polymorphisms and lymphoma	2
Structural localization of pathogenic mutations in the central nucleotide-binding domain (NBD) of nucleotide-binding oligomerization domain-2 (NOD2) protein and their inference in inflammatory disorde	2
Xanthine oxidoreductase knockout mice with high HPRT activity were not rescued by NAD⁺replenishment	2
ATP2B1 genotypes rs2070759 and rs2681472 polymorphisms and risk of hypertension in Saudi population	2
Selective precipitation of RNA with linear polyacrylamide	2
Downregulation of fibrosis related hsa-miR-29c-3p in human CAKUT	2
Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome	2
The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs	2
Effect of IL-6 -174G/C and -572G/C variants on susceptibility to osteoarthritis in Turkish population	2
Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase	2
Association of rs1800795 and rs1800796 polymorphisms in interleukin-6 gene and osteoarthritis risk: evidence from a meta-analysis	2
Adenylated proteins in mouse B16-F10 melanoma cells cluster in functional categories: a new paradigm for cellular regulation?	2
Peroxynitrite-induced conformational changes in DNA that lead to cell death: UV, CD spectral, molecular dynamics simulation and FACS analysis	2
Synthesis and evaluation of antitumor activities of 4-selenopyrimidine derivatives	2
Lactobacillus gasseri PA-3 reduces serum uric acid levels in patients with marginal hyperuricemia	2
DNA numerical encoding schemes for exon prediction: a recent history	2
Circ_0000467 modulates malignant characteristics of colorectal cancer via sponging miR-651-5p and up-regulating DNMT3B	2
Structural insights of the pre-let-7 interaction with LIN28B	2
rs73092672 allele T is significantly associated with the higher risk of breast cancer incidence	1
The effect of DNA repair gene variants on COVID-19 disease: susceptibility, severity, and clinical course	1
The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D-erythro-pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine	1
Molecular assessment of microbial diversity on eggshell of chukar partridges (Alectoris chukar) under semi-captive conditions	1
Genetic association study of CTLA4 and FCεRIα polymorphisms in asthmatic patients in the southwestern region of Iran	1
RNA interference activity of single-stranded oligonucleotides linked between the passenger strand and the guide strand with an aryl phosphate linker	1
A new step in kinetic proofreading due to misacylated-tRNA during ribosomal peptide bond formation	1
Artificial intelligence model with deep learning in nonalcoholic fatty liver disease diagnosis: genetic based artificial neural networks	1
Identification of a new five-gene risk score for risk stratification and prognosis prediction in HCC	1
TNF-α promoter variant (G-308A) is associated with susceptibility to P. falciparum infection and severe malaria: a meta-analysis and trial sequential analysis	1
Determination of total purine and free purine content in milk, soymilk, and enteral nutritional supplements to assist nutritional therapy for hyperuricemia and gout	1
Association of common variants of TCF7L2 and PCSK2 with gestational diabetes mellitus in West Bengal, India	1
RREB1 promotes the development of parafollicular carcinogenesis through the Ras-Raf-1-ELK3 signaling pathway	1
Synthesis, characterization, and biological applications of pyrazole moiety bearing osmium(IV) complexes	1
The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19	1
Alterations in the expression levels of long intergenic non-coding RNA APOC1P1-3 in cervical cancer tissue samples	1
Synthesis, structural elucidation, DNA binding, cleavage, AChE and BuChE cholinesterase efficiencies of metal complexes with 1,10-phenanthroline scaffold	1
Expression of lncRNAs AK058003 and APOC1P1 in breast cancer patients	1
Novel and PCR ready rapid DNA isolation from Drosophila	1
Advancement in specific strand scission of DNA and evaluation of in-vitro biological assessment by pharmacologically significant tetraaza macrocyclic metal complexes constrained by triazole	1
Knockdown of TMEM132A restrains the malignant phenotype of gastric cancer cells via inhibiting Wnt signaling	1
Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539	1
Highly efficient chemical phosphorylation of 6-(4-phenylpiperazine-1-yl)-9-(β-D-ribofuranosyl)-9H-purine	1
Water-soluble nickel (II) Schiff base complexes: Synthesis, structural characterization, DNA binding affinity, DNA cleavage, cytotoxicity, and computational studies	1
Association of IRS-1 and IRS-2 polymorphisms with predisposition to type-2 diabetes (T2D): a meta-analysis and trial sequential analysis	1
Interactive effects of FTO rs9939609 and obesogenic behavioral factors on adiposity-related anthropometric and metabolic phenotypes	1
Evaluating changes in the expression of BCL-2 gene, lncRNA SRA, and miR-361-3p in unexplained recurrent pregnancy loss	1
Looking for the unexpected in purine and pyrimidine metabolism	1
Molecular encapsulation of berberine and ethidium bromide in anthraquinonecarboxamido-β-cyclodextrin conjugate: supramolecular association with DNA duplex and G-quadruplexes	1
Association of ACE ID, MTHFR C677T, and MIF-173GC variants with the clinical course of COVID-19 patients	1
TERT silencing alters the expression of ARG1, GLUL, VIM, NES genes and hsa-miR-29b-3p in the T98G cell line	1
Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase	1
Biocatalyst-mediated selective acylation and deacylation chemistry on the secondary hydroxyl/amine groups of nucleosides	1
Association of ACE I/D, -240A > T and AT1R A1166C polymorphisms with susceptibility to breast cancer: a systematic review and meta-analysis based on 35 case-control studies	1
Organochlorine pesticide residues in agricultural draining water in Tunisia	1
Alkylation of 6-thiopurine derivatives by the Mitsunobu reaction	1

Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome	1
Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O⁶-methylguanine and their recognition by MGMT and Atl1	1
An overview of the role of metallic and nonmetallic nanoparticles and their salts during sperm cryopreservation andin vitroembryo manipulation	1
Purine content of hospital meals and its effect on serum uric acid, urine pH, and urinary uric acid excretion	1
Synthesis, characterization and molecular docking studies of new indol(1H-3-yl)pyrimidine derivatives: Insights into their role in DNA interaction	1
An efficient one pot synthesis of (2-hydroxyphenyl)-5-phenyl-6-(pyrrolidine-1-carbonyl)-1H-pyrano[2,3-d]pyrimidine-2,4(3H,5H)-dione derivatives as a potent biological agents	1
Systematic mapping of DNAzymes research from 1995 to 2019	1
Highly regioselective methylation of inosine nucleotide: an efficient synthesis of 7-methylinosine nucleotide	1
Association of SERPINE1 rs1799889 polymorphism with arterial ischemic stroke in children: a systematic review and meta-analysis	1
Resistance to differentiation affects ribo- and deoxyribonucleotide pools and sensitivity to pyrimidine metabolism antagonists in HL60 cells	1
Synthesis of ribavirin 1,2,3- and 1,2,4-triazolyl analogs with changes at the amide and cytotoxicity in breast cancer cell lines	1
MicroRNA-142-5p promotes the proliferation and metastasis of nasopharyngeal carcinoma	1
Design, synthesis and chemical stability of indolizine derivatives for antidiabetic activity	1
Has_circ_0048764 promotes breast cancer progression by sponging miR-578 and regulating HMGA2 expression	1
Synthesis of new 1,2,3-triazolo-nucleoside analogues with 2-propargylamino pyrimidines via click reactions	1
Fluorescent labeling of s²T-incorporated DNA and m⁵s²U-modified RNA	1
An improved protection-free one-pot chemical synthesis of purine locked nucleic acid nucleoside-5′-triphosphates	1
Following hybridization on sensor/array platforms by using SPR, elipsometer and MALDI-MS	1
Synthesis and in vitro biochemical properties, DNA binding and DNA cleavage ability of copper complexes of hydroxyflavone derivatives of novel organosulfur compounds as therapeutic agent	1
Identification of autophagy and angiogenesis modulators in colorectal cancer based on bioinformatics analysis	1
SLC23A3 is a renal hypoxanthine transporter	1
Effect of vitamin D receptor gene BsmI polymorphism on hospitalization of SARS-CoV-2 positive patients	1
The association of PRNCR1 rs1456315 polymorphism with the risk of colorectal cancer	1
Nucleotide metabolism during experimental preservation for transplantation with Transmedium Transplant Fluid (TTF) in comparison to Histidine-Tryptophan-Ketoglutarate (HTK)	1
A circadian rhythm gene (PER3) VNTR variant as possible risk factor in cohort of Turkish females with primary dysmenorrhea	1
Modified forearm ischemic test in hypouricemic patients	1
VEGF and eNOS variants may influence intervertebral disc degeneration	1
Structural and functional analysis of human thymidylate kinase isoforms	1
Climate change: approach to intervention using expression vector for carbonic anhydrase via glycosylphosphatidylinositol	1
The risk of relapse in breast cancer patients is associated with MMP-9 gene polymorphism: a prospective study in a sample of the Iranian population	1
Association between PAX8AS1 (rs4848320 C > T, rs1110839 G > T, and rs6726151 T > G) and MEG3 (rs7158663) gene polymorphisms and non-Hodgkin lymphoma risk	1
The decreased serum activity of cytosolic 5′-nucleotidase IA as a potential marker of breast cancer-associated muscle inflammation	1
PSAT1gene as a biomarker for targeting triple negative breast cancer in presence of Rapamycin	1
The effect of trehalose on intracellular and extracellular nucleotide metabolism. A pilot study	1