Antioxidants & Redox Signaling

Papers
(The TQCC of Antioxidants & Redox Signaling is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Regulatory Phenomena in the Glutathione Peroxidase Superfamily208
Metabolic Responses to Reductive Stress206
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease169
Is Albumin Predictor of Mortality in COVID-19?117
Senescence in Post-Mitotic Cells: A Driver of Aging?112
Mitochondrial Reactive Oxygen Species and Mitophagy: A Complex and Nuanced Relationship104
Oxidative Stress and Endothelial Dysfunction in Sepsis and Acute Inflammation99
Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis84
Is Low Alveolar Type II CellSOD3in the Lungs of Elderly Linked to the Observed Severity of COVID-19?78
Vitamin C in Plants: Novel Concepts, New Perspectives, and Outstanding Issues76
Direct Proteomic Mapping of Cysteine Persulfidation75
Mitochondrial Superoxide Dismutase: What the Established, the Intriguing, and the Novel Reveal About a Key Cellular Redox Switch74
Reactive Oxygen Species Induced p53 Activation: DNA Damage, Redox Signaling, or Both?74
Redox RegulationviaGlutaredoxin-1 and ProteinS-Glutathionylation68
Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis67
2-Hydroxyglutarate in Cancer Cells67
Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery65
Autophagy in Female Fertility: A Role in Oxidative Stress and Aging64
Central and Peripheral Metabolic Defects Contribute to the Pathogenesis of Alzheimer's Disease: Targeting Mitochondria for Diagnosis and Prevention59
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Radiation-Induced Lung Injury via miRNA-214-3p58
Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice57
Effects of Hydrogen Sulfide on the Microbiome: From Toxicity to Therapy55
Neuroprotective Effects of Trilobatin, a Novel Naturally Occurring Sirt3 Agonist from Lithocarpus polystachyus Rehd., Mitigate Cerebral Ischemia/Reperfusion Injury: Involvement of TLR4/NF-κB an53
Redox Systems Biology: Harnessing the Sentinels of the Cysteine Redoxome52
Cell Senescence, DNA Damage, and Metabolism52
Targeting Hypoxia-Inducible Factor-1-Mediated Metastasis for Cancer Therapy52
Inflammation and Oxidative Stress in Chronic Kidney Disease and Dialysis Patients52
Lipid Peroxidation in Atherosclerotic Cardiovascular Diseases51
Loop Between NLRP3 Inflammasome and Reactive Oxygen Species50
Adaptive Responses to Hypoxia and/or Hyperoxia in Humans50
Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism50
Redox Biology of Human Cumulus Cells: Basic Concepts, Impact on Oocyte Quality, and Potential Clinical Use49
The NADPH Oxidase Family and Its Inhibitors49
Precision Redox: The Key for Antioxidant Pharmacology48
Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension48
Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension47
Natural Molecules Targeting Thioredoxin System and Their Therapeutic Potential45
Nuclear Factor Kappa B Signaling Complexes in Acute Inflammation45
Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders45
Bacterial Oxidases of the CytochromebdFamily: Redox Enzymes of Unique Structure, Function, and Utility As Drug Targets45
Inhibiting the Activity of NADPH Oxidase in Cancer44
S-Persulfidation: Chemistry, Chemical Biology, and Significance in Health and Disease43
Procyanidin B2 Promotes Intestinal Injury Repair and Attenuates Colitis-Associated Tumorigenesis via Suppression of Oxidative Stress in Mice43
Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress42
Regulation of the Expression of Heme Oxygenase-1: Signal Transduction, Gene Promoter Activation, and Beyond42
Heme-Oxygenase-141
NADPH Oxidase Inhibition: Preclinical and Clinical Studies in Diabetic Complications40
Vascular Extracellular Matrix Remodeling and Hypertension40
Ferroptosis: Biological Rust of Lipid Membranes40
NRF2 and Hypoxia-Inducible Factors: Key Players in the Redox Control of Systemic Iron Homeostasis40
Myeloperoxidase As a Multifaceted Target for Cardiovascular Protection39
Cardiac Damage in Anthracyclines Therapy: Focus on Oxidative Stress and Inflammation39
The Tricarboxylic Acid Cycle at the Crossroad Between Cancer and Immunity39
Pathogenic Role of Air Pollution Particulate Matter in Cardiometabolic Disease: Evidence from Mice and Humans39
Nuclear Factor Erythroid-Derived 2-Like 2-Induced Reductive Stress Favors Self-Renewal of Breast Cancer Stem-Like Cellsviathe FoxO3a-Bmi-1 Axis38
A Novel Identified Circular RNA, mmu_mmu_circRNA_0000309, Involves in Germacrone-Mediated Improvement of Diabetic Nephropathy Through Regulating Ferroptosis by Targeting miR-188-3p/GPX4 Signaling Axis38
N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 201937
Targeting Oxidative Stress and Inflammatory Response for Blood–Brain Barrier Protection in Intracerebral Hemorrhage37
The Interplay Between Systemic Inflammation, Oxidative Stress, and Tissue Remodeling in Tuberculosis37
The Potent Antioxidant MitoQ Protects Against Preeclampsia During Late Gestation but Increases the Risk of Preeclampsia When Administered in Early Pregnancy36
Nitric Oxide-Dependent Protein Post-Translational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases36
Hydrogen Sulfide in Inflammation: A Novel Mediator and Therapeutic Target35
The Redox Theory of Development35
Roles of Perivascular Adipose Tissue in Hypertension and Atherosclerosis35
Hepatokine Selenoprotein P-Mediated Reductive Stress Causes Resistance to Intracellular Signal Transduction34
Altered Metabolism in Alzheimer Disease Brain: Role of Oxidative Stress34
Signaling Pathways Underlying Anthracycline Cardiotoxicity34
Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease34
Inflammation, Lipid (Per)oxidation, and Redox Regulation34
Mitophagy and Its Contribution to Metabolic and Aging-Associated Disorders34
Sulfur Dioxide: Endogenous Generation, Biological Effects, Detection, and Therapeutic Potential34
Selenoprotein T: An Essential Oxidoreductase Serving as a Guardian of Endoplasmic Reticulum Homeostasis33
Interplay Between Oxidative Stress, Cyclooxygenases, and Prostanoids in Cardiovascular Diseases33
Bioinformatics of Selenoproteins33
Are Reactive Sulfur Species the New Reactive Oxygen Species?32
Golgi Stress Response, Hydrogen Sulfide Metabolism, and Intracellular Calcium Homeostasis31
Redox Control of Proteolysis During Inactivity-Induced Skeletal Muscle Atrophy31
Oxidative Stress in Oocytes and Embryo Development: Implications for In Vitro Systems30
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetas30
Reductive Stress: New Insights in Physiology and Drug Tolerance ofMycobacterium30
Caveolin-1 Alleviates Diabetes-Associated Cognitive Dysfunction Through Modulating Neuronal Ferroptosis-Mediated Mitochondrial Homeostasis29
Oxidative Stress and Cancer Development: Are Noncoding RNAs the Missing Links?29
Redox Signaling in Widespread Health Benefits of Exercise29
Mechanisms Involved in Cardioprotection Induced by Physical Exercise29
A Global Profile of Reversible and Irreversible Cysteine Redox Post-Translational Modifications During Myocardial Ischemia/Reperfusion Injury and Antioxidant Intervention28
Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity28
High Copper Complex Stability and Slow Reduction Kinetics as Key Parameters for Improved Activity, Paraptosis Induction, and Impact on Drug-Resistant Cells of Anticancer Thiosemicarbazones28
The Role and Mechanism of Intestinal Flora in Blood Pressure Regulation and Hypertension Development28
Preventive and Therapeutic Potential of Physical Exercise in Neurodegenerative Diseases28
Chemical Biology of Reactive Sulfur Species: Hydrolysis-Driven Equilibrium of Polysulfides as a Determinant of Physiological Functions28
Oxidative Stress and Hypoxia Modify Mitochondrial Homeostasis During Glaucoma27
Activation of Farnesoid X Receptor by Schaftoside Ameliorates Acetaminophen-Induced Hepatotoxicity by Modulating Oxidative Stress and Inflammation27
Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease27
Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage27
Vitamin C and Cell Death27
MicroRNAs As Master Regulators of Atherosclerosis: From Pathogenesis to Novel Therapeutic Options27
The Dual Role of Reactive Oxygen Species-Generating Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Gastrointestinal Inflammation and Therapeutic Perspectives27
Autophagy-Dependent Ferroptosis in Cancer27
COVID-19: A Redox Disease—What a Stress Pandemic Can Teach Us About Resilience and What We May Learn from the Reactive Species Interactome About Its Treatment27
Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model26
Physical and Functional Cross Talk Between Endo-Sarcoplasmic Reticulum and Mitochondria in Skeletal Muscle26
SG1002 and Catenated Divalent Organic Sulfur Compounds as Promising Hydrogen Sulfide Prodrugs26
Tetrahydrobiopterin in Cell Function and Death Mechanisms25
Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin25
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity25
Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation25
Reductive Stress, Bioactive Compounds, Redox-Active Metals, and Dormant Tumor Cell Biology to Develop Redox-Based Tools for the Treatment of Cancer25
Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids25
Aberrant Upregulation of Compensatory Redox Molecular Machines May Contribute to Sperm Dysfunction in Infertile Men with Unilateral Varicocele: A Proteomic Insight25
Plant Chloroplast Stress Response: Insights from Thiol Redox Proteomics25
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP124
Endogenous and Exogenous Antioxidants As a Tool to Ameliorate Male Infertility Induced by Reactive Oxygen Species24
The MAVS Immune Recognition Pathway in Viral Infection and Sepsis24
Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron−Sulfur Cluster Biogenesis Deficit24
Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction24
High-Precision Sulfur Metabolomics Innovated by a New Specific Probe for Trapping Reactive Sulfur Species24
Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective24
The Redox Balance: A Target for Interventions Against Muscle Wasting in Cancer Cachexia?24
Pyroptosis and Redox Balance in Kidney Diseases23
Role of Mitochondria-Derived Danger Signals Released After Injury in Systemic Inflammation and Sepsis23
Circadian Control of Mitochondria in Reactive Oxygen Species Homeostasis23
Sulfur Metabolism Under Stress23
Targeting Toll-Like Receptors in Sepsis: From Bench to Clinical Trials23
Mitochondrial Fusion, Fission, and Mitophagy in Cardiac Diseases: Challenges and Therapeutic Opportunities23
Antioxidant Enzymes and Male Fertility: Lessons from Knockout Models23
Hypoxic-Ischemic Encephalopathy and Mitochondrial Dysfunction: Facts, Unknowns, and Challenges23
Human Disorders Affecting the Selenocysteine Incorporation Pathway Cause Systemic Selenoprotein Deficiency22
Abrogation of Toll-Like Receptor 4 Mitigates Obesity-Induced Oxidative Stress, Proinflammation, and Insulin Resistance Through Metabolic Reprogramming of Mitochondria in Adipose Tissue22
Diabetes–Alzheimer's Disease Link: Targeting Mitochondrial Dysfunction and Redox Imbalance22
Nicotinamide Adenine Dinucleotide Phosphate Oxidase and Neurodegenerative Diseases: Mechanisms and Therapy22
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic β Cells Due to Decreasing Mitochondrial Matrix NADH/NAD+Ratio22
Measuring Reactive Sulfur Species and Thiol Oxidation States: Challenges and Cautions in Relation to Alkylation-Based Protocols22
Hypoxia-Activated Prodrug Evofosfamide Treatment in Pancreatic Ductal Adenocarcinoma Xenografts Alters the Tumor Redox Status to Potentiate Radiotherapy22
Neutrophil-Mediated Cardiac Damage After Acute Myocardial Infarction: Significance of Defining a New Target Cell Type for Developing Cardioprotective Drugs22
Sex Differences in Nonalcoholic Fatty Liver Disease: Estrogen Influence on the Liver–Adipose Tissue Crosstalk21
The Reactive Species Interactome in the Brain21
The Multifaceted ATPase Inhibitory Factor 1 (IF1) in Energy Metabolism Reprogramming and Mitochondrial Dysfunction: A New Player in Age-Associated Disorders?21
Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with β-Catenin21
PDK4 Decrease Neuronal Apoptosis via Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage21
Phosphoglycerate Mutase 5 Knockdown Alleviates Neuronal Injury After Traumatic Brain Injury Through Drp1-Mediated Mitochondrial Dysfunction21
Regulation of the 20S Proteasome by a Novel Family of Inhibitory Proteins21
The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease21
Heme Causes Pain in Sickle Mice via Toll-Like Receptor 4-Mediated Reactive Oxygen Species- and Endoplasmic Reticulum Stress-Induced Glial Activation21
Oxidative Stress and Mitochondrial Dysfunction Associated with Peripheral Neuropathy in Type 1 Diabetes20
Vitamin K2 Alleviates Insulin Resistance in Skeletal Muscle by Improving Mitochondrial FunctionViaSIRT1 Signaling20
NADPH Oxidase Inhibition in Fibrotic Pathologies20
Omega-3 Polyunsaturated Fatty Acids: Versatile Roles in Blood Pressure Regulation20
Oxidant Stress and Acetaminophen Hepatotoxicity: Mechanism-Based Drug Development20
WhenS-Nitrosylation Gets to Mitochondria: From Signaling to Age-Related Diseases20
Peri/Epicellular Thiol Oxidoreductases as Mediators of Extracellular Redox Signaling20
Liquid Biopsies: Microvesicles in Cardiovascular Disease20
Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases19
Anti-Allergic and Anti-Inflammatory Effects and Molecular Mechanisms of Thioredoxin on Respiratory System Diseases19
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy19
Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders19
New Therapeutic Approaches Using Hydrogen Sulfide Donors in Inflammation and Immune Response19
Salt Sensitivity of Blood Pressure in Blacks and Women: A Role of Inflammation, Oxidative Stress, and Epithelial Na+ Channel19
Renal Dopamine Receptors and Oxidative Stress: Role in Hypertension19
Extracellular Matrix and Oxidative Stress Following Traumatic Spinal Cord Injury: Physiological and Pathophysiological Roles and Opportunities for Therapeutic Intervention19
The Interplay Between Mitochondrial Reactive Oxygen Species, Endoplasmic Reticulum Stress, and Nrf2 Signaling in Cardiometabolic Health19
Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease19
The Asparagine Hydroxylase FIH: A Unique Oxygen Sensor18
Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses18
Redox Activation of Mitochondrial DAMPs and the Metabolic Consequences for Development of Autoimmunity18
Thioredoxin-Interacting Protein in Cancer and Diabetes18
Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles?18
Impact of Acute and Chronic Psychosocial Stress on Vascular Inflammation18
Environmental Factors Such as Noise and Air Pollution and Vascular Disease17
Damage-Associated Molecular Patterns As Double-Edged Swords in Sepsis17
Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution17
Reactive Oxygen Species/Reactive Nitrogen Species as Messengers in the Gut: Impact on Physiology and Metabolic Disorders17
Activation of Endogenous H2S Biosynthesis or Supplementation with Exogenous H2S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans17
Omics Integration for Mitochondria Systems Biology17
Mitochondrial and Redox-Based Therapeutic Strategies in Huntington's Disease17
Non-Transferrin-Bound Iron in the Spotlight: Novel Mechanistic Insights into the Vasculotoxic and Atherosclerotic Effect of Iron17
Prodrugs of Persulfides, Sulfur Dioxide, and Carbon Disulfide: Important Tools for Studying Sulfur Signaling at Various Oxidation States17
Mycobacterial and Human Nitrobindins: Structure and Function17
Epigenetic Remodeling in Obesity-Related Vascular Disease17
Staphylococcus aureus, Antibiotic Resistance, and the Interaction with Human Neutrophils17
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