Antioxidants & Redox Signaling

Article	Citations
Oxidative Stress and Endothelial Dysfunction in Sepsis and Acute Inflammation	135
Mitochondrial Reactive Oxygen Species and Mitophagy: A Complex and Nuanced Relationship	129
Senescence in Post-Mitotic Cells: A Driver of Aging?	126
Is Albumin Predictor of Mortality in COVID-19?	125
Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis	101
2-Hydroxyglutarate in Cancer Cells	86
Direct Proteomic Mapping of Cysteine Persulfidation	81
Loop Between NLRP3 Inflammasome and Reactive Oxygen Species	76
Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis	74
Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension	70
Effects of Hydrogen Sulfide on the Microbiome: From Toxicity to Therapy	68
Lipid Peroxidation in Atherosclerotic Cardiovascular Diseases	66
Targeting Oxidative Stress and Inflammatory Response for Blood–Brain Barrier Protection in Intracerebral Hemorrhage	66
Inflammation and Oxidative Stress in Chronic Kidney Disease and Dialysis Patients	65
Adaptive Responses to Hypoxia and/or Hyperoxia in Humans	65
Bacterial Oxidases of the CytochromebdFamily: Redox Enzymes of Unique Structure, Function, and Utility As Drug Targets	64
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Radiation-Induced Lung Injury via miRNA-214-3p	63
Cell Senescence, DNA Damage, and Metabolism	62
Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders	62
Precision Redox: The Key for Antioxidant Pharmacology	60
Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension	59
Targeting Hypoxia-Inducible Factor-1-Mediated Metastasis for Cancer Therapy	56
Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress	54
Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism	53
A Novel Identified Circular RNA, mmu_mmu_circRNA_0000309, Involves in Germacrone-Mediated Improvement of Diabetic Nephropathy Through Regulating Ferroptosis by Targeting miR-188-3p/GPX4 Signaling Axis	51

Ferroptosis: Biological Rust of Lipid Membranes	51
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetas	50
S-Persulfidation: Chemistry, Chemical Biology, and Significance in Health and Disease	50
Natural Molecules Targeting Thioredoxin System and Their Therapeutic Potential	49
Sulfur Dioxide: Endogenous Generation, Biological Effects, Detection, and Therapeutic Potential	49
Procyanidin B2 Promotes Intestinal Injury Repair and Attenuates Colitis-Associated Tumorigenesis via Suppression of Oxidative Stress in Mice	48
Caveolin-1 Alleviates Diabetes-Associated Cognitive Dysfunction Through Modulating Neuronal Ferroptosis-Mediated Mitochondrial Homeostasis	48
Vascular Extracellular Matrix Remodeling and Hypertension	48
NRF2 and Hypoxia-Inducible Factors: Key Players in the Redox Control of Systemic Iron Homeostasis	46
Autophagy-Dependent Ferroptosis in Cancer	45
The Interplay Between Systemic Inflammation, Oxidative Stress, and Tissue Remodeling in Tuberculosis	45
Roles of Perivascular Adipose Tissue in Hypertension and Atherosclerosis	45
Hydrogen Sulfide in Inflammation: A Novel Mediator and Therapeutic Target	44
Altered Metabolism in Alzheimer Disease Brain: Role of Oxidative Stress	44
N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 2019	42
Interplay Between Oxidative Stress, Cyclooxygenases, and Prostanoids in Cardiovascular Diseases	40
The Potent Antioxidant MitoQ Protects Against Preeclampsia During Late Gestation but Increases the Risk of Preeclampsia When Administered in Early Pregnancy	38
Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease	38
The KEAP1-NRF2 System and Neurodegenerative Diseases	36
Tetrahydrobiopterin in Cell Function and Death Mechanisms	36
Circadian Control of Mitochondria in Reactive Oxygen Species Homeostasis	35
Selenoprotein T: An Essential Oxidoreductase Serving as a Guardian of Endoplasmic Reticulum Homeostasis	35
Oxidative Stress and Hypoxia Modify Mitochondrial Homeostasis During Glaucoma	35
Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease	34
Vitamin C and Cell Death	34
Are Reactive Sulfur Species the New Reactive Oxygen Species?	34
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity	33
Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model	32
Preventive and Therapeutic Potential of Physical Exercise in Neurodegenerative Diseases	32
COVID-19: A Redox Disease—What a Stress Pandemic Can Teach Us About Resilience and What We May Learn from the Reactive Species Interactome About Its Treatment	32
Sulfur Metabolism Under Stress	31
PDK4 Decrease Neuronal Apoptosis via Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage	31
Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective	31
The MAVS Immune Recognition Pathway in Viral Infection and Sepsis	31
The Role and Mechanism of Intestinal Flora in Blood Pressure Regulation and Hypertension Development	31
Chemical Biology of Reactive Sulfur Species: Hydrolysis-Driven Equilibrium of Polysulfides as a Determinant of Physiological Functions	31
Oxidative Stress and Cancer Development: Are Noncoding RNAs the Missing Links?	31
Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity	31
A Global Profile of Reversible and Irreversible Cysteine Redox Post-Translational Modifications During Myocardial Ischemia/Reperfusion Injury and Antioxidant Intervention	30
Mitochondrial Fusion, Fission, and Mitophagy in Cardiac Diseases: Challenges and Therapeutic Opportunities	30
Oxidative Stress and Mitochondrial Dysfunction Associated with Peripheral Neuropathy in Type 1 Diabetes	30
Pyroptosis and Redox Balance in Kidney Diseases	30
Oxidative Stress in Oocytes and Embryo Development: Implications for In Vitro Systems	30
Extracellular Matrix and Oxidative Stress Following Traumatic Spinal Cord Injury: Physiological and Pathophysiological Roles and Opportunities for Therapeutic Intervention	29
SG1002 and Catenated Divalent Organic Sulfur Compounds as Promising Hydrogen Sulfide Prodrugs	29
Oxidant Stress and Acetaminophen Hepatotoxicity: Mechanism-Based Drug Development	29
Role of Mitochondria-Derived Danger Signals Released After Injury in Systemic Inflammation and Sepsis	28
The Multifaceted ATPase Inhibitory Factor 1 (IF1) in Energy Metabolism Reprogramming and Mitochondrial Dysfunction: A New Player in Age-Associated Disorders?	28
Sex Differences in Nonalcoholic Fatty Liver Disease: Estrogen Influence on the Liver–Adipose Tissue Crosstalk	28
Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron−Sulfur Cluster Biogenesis Deficit	28

High-Precision Sulfur Metabolomics Innovated by a New Specific Probe for Trapping Reactive Sulfur Species	28
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1	28
Hypoxia-Activated Prodrug Evofosfamide Treatment in Pancreatic Ductal Adenocarcinoma Xenografts Alters the Tumor Redox Status to Potentiate Radiotherapy	27
Targeting Toll-Like Receptors in Sepsis: From Bench to Clinical Trials	27
Redox Activation of Mitochondrial DAMPs and the Metabolic Consequences for Development of Autoimmunity	27
Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles?	27
Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with β-Catenin	26
Renal Dopamine Receptors and Oxidative Stress: Role in Hypertension	26
LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity	26
Diabetes–Alzheimer's Disease Link: Targeting Mitochondrial Dysfunction and Redox Imbalance	26
Endoplasmic Reticulum-Mitochondria Contacts Modulate Reactive Oxygen Species-Mediated Signaling and Oxidative Stress in Brain Disorders: The Key Role of Sigma-1 Receptor	26
The Reactive Species Interactome in the Brain	25
Salt Sensitivity of Blood Pressure in Blacks and Women: A Role of Inflammation, Oxidative Stress, and Epithelial Na+ Channel	25
Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids	25
Heme Causes Pain in Sickle Mice via Toll-Like Receptor 4-Mediated Reactive Oxygen Species- and Endoplasmic Reticulum Stress-Induced Glial Activation	25
Phosphoglycerate Mutase 5 Knockdown Alleviates Neuronal Injury After Traumatic Brain Injury Through Drp1-Mediated Mitochondrial Dysfunction	25
The Asparagine Hydroxylase FIH: A Unique Oxygen Sensor	24
Staphylococcus aureus, Antibiotic Resistance, and the Interaction with Human Neutrophils	24
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy	24
Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders	24
Vitamin K2 Alleviates Insulin Resistance in Skeletal Muscle by Improving Mitochondrial FunctionViaSIRT1 Signaling	23
Measuring Reactive Sulfur Species and Thiol Oxidation States: Challenges and Cautions in Relation to Alkylation-Based Protocols	23
Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution	23
Thioredoxin-Interacting Protein in Cancer and Diabetes	23
Reactive Oxygen Species/Reactive Nitrogen Species as Messengers in the Gut: Impact on Physiology and Metabolic Disorders	23
Damage-Associated Molecular Patterns As Double-Edged Swords in Sepsis	22
The Interplay Between Mitochondrial Reactive Oxygen Species, Endoplasmic Reticulum Stress, and Nrf2 Signaling in Cardiometabolic Health	22
Omega-3 Polyunsaturated Fatty Acids: Versatile Roles in Blood Pressure Regulation	22
Mitochondrial Cristae Morphology Reflecting Metabolism, Superoxide Formation, Redox Homeostasis, and Pathology	22
Autophagy and Apoptosis in Acute Brain Injuries: From Mechanism to Treatment	21
Impact of Acute and Chronic Psychosocial Stress on Vascular Inflammation	21
New Therapeutic Approaches Using Hydrogen Sulfide Donors in Inflammation and Immune Response	21
The Aging Liver: Redox Biology and Liver Regeneration	20
Non-Transferrin-Bound Iron in the Spotlight: Novel Mechanistic Insights into the Vasculotoxic and Atherosclerotic Effect of Iron	20
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition	20
Emerging Chemical Biology of Protein Persulfidation	20
Epigenetic Remodeling in Obesity-Related Vascular Disease	20
Oxidative Modification of Proteins: From Damage to Catalysis, Signaling, and Beyond	20
Mitochondrial NAD(P)+Transhydrogenase: From Molecular Features to Physiology and Disease	20
The BET Protein Inhibitor Apabetalone Rescues Diabetes-Induced Impairment of Angiogenic Response by Epigenetic Regulation of Thrombospondin-1	20
Macrophage Regulation of Granulopoiesis and Neutrophil Functions	20
Divergent Sepsis Pathophysiology in Older Adults	20
Oxidative Stress in Neutrophils: Implications for Diabetic Cardiovascular Complications	19
Chemiluminescence Measurement of Reactive Sulfur and Nitrogen Species	19
Hydrogen Sulfide and the Kidney: Physiological Roles, Contribution to Pathophysiology, and Therapeutic Potential	19
Diet and Hydrogen Sulfide Production in Mammals	19
The Complement Pathway: New Insights into Immunometabolic Signaling in Diabetic Kidney Disease	19
Prodrugs of Persulfides, Sulfur Dioxide, and Carbon Disulfide: Important Tools for Studying Sulfur Signaling at Various Oxidation States	19
Nox, Nox, Are You There? The Role of NADPH Oxidases in the Peripheral Nervous System	19
Redox Biology of Melatonin: Discriminating Between Circadian and Noncircadian Functions	19
Role of Paraoxonase1 in the Regulation of High-Density Lipoprotein Functionality and in Cardiovascular Protection	18
Imperatorin Alleviates Psoriasiform Dermatitis by Blocking Neutrophil Respiratory Burst, Adhesion, and Chemotaxis Through Selective Phosphodiesterase 4 Inhibition	18
Nitrosopersulfide (SSNO−) Is a Unique Cysteine Polysulfidating Agent with Reduction-Resistant Bioactivity	18
Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells	18
Predicting the Possible Physiological/Biological Utility of the Hydropersulfide Functional Group Based on Its Chemistry: Similarities Between Hydropersulfides and Selenols	18
The Landscape of Coding and Noncoding RNAs in Platelets	18
Activation of Endogenous H2S Biosynthesis or Supplementation with Exogenous H2S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans	18
Oxidative Post-Translational Modifications: A Focus on Cysteine S-Sulfhydration and the Regulation of Endothelial Fitness	18
Does Metformin Modulate Mitochondrial Dynamics and Function in Type 2 Diabetic Patients?	17
Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging	17
Hypoxia Imaging As a Guide for Hypoxia-Modulated and Hypoxia-Activated Therapy	17
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway	17
Contribution of Mitochondria to Insulin Secretion by Various Secretagogues	17
Dihydrotanshinone I Attenuates Plaque Vulnerability in Apolipoprotein E-Deficient Mice: Role of Receptor-Interacting Protein 3	17
Mitochondrial and Redox-Based Therapeutic Strategies in Huntington's Disease	17
Redox and Epigenetics in Human Pluripotent Stem Cells Differentiation	17
Reactive Oxygen Species and Their Consequences on the Structure and Function of Mammalian Spermatozoa	16
The Role of Iron in Benign and Malignant Hematopoiesis	16
Glycomacropeptide: A Bioactive Milk Derivative to Alleviate Metabolic Syndrome Outcomes	16
Development of Hydropersulfide Donors to Study Their Chemical Biology	16
Mitochondria-Targeted Therapeutics for Alzheimer's Disease: The Good, the Bad, the Potential	16
Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Protect Against UVA-Induced Photoaging in Human Dermal Fibroblasts, and in Mouse Skin In Vivo	16
Red Blood Cells as a “Central Hub” for Sulfide Bioactivity: Scavenging, Metabolism, Transport, and Cross-Talk with Nitric Oxide	16
Molecular Insights and Functional Consequences of the Interaction of Heme with Activated Protein C	16
Surviving and Adapting to Stress: Translational Control and the Integrated Stress Response	16
From Development to Aging: The Path to Cellular Senescence	16
Methods for Suppressing Hydrogen Sulfide in Biological Systems	16
miR-210 hypoxamiR in Angiogenesis and Diabetes	16
Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis	16
Redox Regulation to Modulate Phosphorylation Events in Human Spermatozoa	16

Do Levels of Lipid Peroxidation Biomarkers Reflect the Degree of Brain Injury in Newborns?

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