American Journal of Physiology-Renal Physiology

Papers
(The TQCC of American Journal of Physiology-Renal Physiology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Is the kidney a target of SARS-CoV-2?144
Preeclampsia beyond pregnancy: long-term consequences for mother and child110
A role for tubular Na+/H+exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin108
Mitochondrial dysfunction and the AKI-to-CKD transition89
Uric acid and inflammation in kidney disease67
Evaluation of cisplatin-induced injury in human kidney organoids56
Sex differences in solute transport along the nephrons: effects of Na+transport inhibition55
Mitochondrial transplantation by intra-arterial injection for acute kidney injury42
The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction40
Differences in renal BMAL1 contribution to Na+ homeostasis and blood pressure control in male and female mice40
Distal convoluted tubule Clconcentration is modulated via K+channels and transporters37
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1receptor and TRPV137
Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model36
Beclin 1/Bcl-2 complex-dependent autophagy activity modulates renal susceptibility to ischemia-reperfusion injury and mediates renoprotection by Klotho34
Effects of SGLT2 inhibitor and dietary NaCl on glomerular hemodynamics assessed by micropuncture in diabetic rats34
Urine cytokines as biomarkers for diagnosing interstitial cystitis/bladder pain syndrome and mapping its clinical characteristics33
Sex differences in renal ischemia-reperfusion injury33
ELABELA antagonizes intrarenal renin-angiotensin system to lower blood pressure and protects against renal injury33
Decreased secretion and profibrotic activity of tubular exosomes in diabetic kidney disease31
miR-214 represses mitofusin-2 to promote renal tubular apoptosis in ischemic acute kidney injury31
Effects of a prolyl hydroxylase inhibitor on kidney and cardiovascular complications in a rat model of chronic kidney disease31
Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin30
Reduced O-GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney28
Loss of circadian gene Bmal1 in the collecting duct lowers blood pressure in male, but not female, mice27
Evolution of altered tubular metabolism and mitochondrial function in sepsis-associated acute kidney injury27
Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies26
Class IIa HDAC inhibitor TMP195 alleviates lipopolysaccharide-induced acute kidney injury26
IL-6trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane26
Gene knockout of the Na+-glucose cotransporter SGLT2 in a murine model of acute kidney injury induced by ischemia-reperfusion25
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation25
Skeletal myopathy in CKD: a comparison of adenine-induced nephropathy and 5/6 nephrectomy models in mice25
Transplanted senescent renal scattered tubular-like cells induce injury in the mouse kidney25
Distal convoluted tubule sexual dimorphism revealed by advanced 3D imaging24
The complicated role of mitochondria in the podocyte24
Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition24
A plasma creatinine- and urea-based equation to estimate glomerular filtration rate in rats24
Sex differences in renal mitochondrial function: a hormone-gous opportunity for research24
Acute and chronic glomerular damage is associated with reduced CD133 expression in urinary extracellular vesicles24
Tubule-derived lactate is required for fibroblast activation in acute kidney injury24
Nrf2 mediates hypoxia-inducible HIF1α activation in kidney tubular epithelial cells24
Salt-sensitive hypertension in chronic kidney disease: distal tubular mechanisms24
C57BL/6 mice require a higher dose of cisplatin to induce renal fibrosis and CCL2 correlates with cisplatin-induced kidney injury23
Histone deacetylase 6 inhibition mitigates renal fibrosis by suppressing TGF-β and EGFR signaling pathways in obstructive nephropathy23
Cerebral blood flow regulation in end-stage kidney disease23
Acid-sensing ion channels in sensory signaling23
METTL3 contributes to renal ischemia-reperfusion injury by regulating Foxd1 methylation23
Adaptive changes in single-nephron GFR, tubular morphology, and transport in a pregnant rat nephron: modeling and analysis22
Effects of extreme potassium stress on blood pressure and renal tubular sodium transport22
Inflammatory macrophages in the kidney contribute to salt-sensitive hypertension22
Glucagon-like peptide-1 receptors in the kidney: impact on renal autoregulation22
Critical role of the mineralocorticoid receptor in aldosterone-dependent and aldosterone-independent regulation of ENaC in the distal nephron22
Medullary and cortical thick ascending limb: similarities and differences22
Canagliflozin reduces cisplatin uptake and activates Akt to protect against cisplatin-induced nephrotoxicity22
Inhibition of PDE4/PDE4B improves renal function and ameliorates inflammation in cisplatin-induced acute kidney injury22
Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease21
Long noncoding RNA NEAT1 sponges miR-129 to modulate renal fibrosis by regulation of collagen type I21
CRISPR-Cas9/phosphoproteomics identifies multiple noncanonical targets of myosin light chain kinase20
Liraglutide suppresses production of extracellular matrix proteins and ameliorates renal injury of diabetic nephropathy by enhancing Wnt/β-catenin signaling20
Mesenchymal stem cells protect renal tubular cells via TSG-6 regulating macrophage function and phenotype switching20
Novel Fanconi renotubular syndromes provide insights in proximal tubule pathophysiology20
High-fructose corn syrup-sweetened soft drink consumption increases vascular resistance in the kidneys at rest and during sympathetic activation20
Expression, localization, and functional properties of inwardly rectifying K+channels in the kidney20
Regulated cell death in cisplatin-induced AKI: relevance of myo-inositol metabolism20
Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats19
Urinary bladder smooth muscle ion channels: expression, function, and regulation in health and disease19
Sex-specific computational models for blood pressure regulation in the rat19
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment18
Soluble (pro)renin receptor regulation of ENaC involved in aldosterone signaling in cultured collecting duct cells18
Disparate roles of retinoid acid signaling molecules in kidney disease18
Metformin arrests the progression of established kidney disease in the subtotal nephrectomy model of chronic kidney disease18
Effects of uric acid dysregulation on the kidney17
Roles of WNK4 and SPAK in K+-mediated dephosphorylation of the NaCl cotransporter17
T cell-derived extracellular vesicles are elevated in essential HTN17
CCL2 mediates early renal leukocyte infiltration during salt-sensitive hypertension17
Expression of lactate dehydrogenase A and B isoforms in the mouse kidney17
Beneficial effect on podocyte number in experimental diabetic nephropathy resulting from combined atrasentan and RAAS inhibition therapy17
Localization and regulation of claudin-14 in experimental models of hypercalcemia16
Vitamin K deficiency: an emerging player in the pathogenesis of vascular calcification and an iatrogenic consequence of therapies in advanced renal disease16
Synaptopodin deficiency exacerbates kidney disease in a mouse model of Alport syndrome16
Alkali supplementation as a therapeutic in chronic kidney disease: what mediates protection?16
Fasting-induced HMGCS2 expression in the kidney does not contribute to circulating ketones16
Rapid development of vasopressin resistance in dietary K+ deficiency16
Ubiquitination of renal ENaC subunits in vivo16
Regulation of mitochondrial dynamics and energetics in the diabetic renal proximal tubule by the β2-adrenergic receptor agonist formoterol16
Overexpression of TGF-β1 induces renal fibrosis and accelerates the decline in kidney function in polycystic kidney disease16
SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats16
Downregulation of PTEN promotes podocyte endocytosis of lipids aggravating obesity-related glomerulopathy16
TCR+CD4CD8 (double negative) T cells protect from cisplatin-induced renal epithelial cell apoptosis and acute kidney injury16
Potential risk of the kidney vulnerable to novel coronavirus 2019 infection16
Sex differences in circadian regulation of kidney function of the mouse16
Does sex matter?: an update on the implementation of sex as a biological variable in research15
Chronic exercise provides renal-protective effects with upregulation of fatty acid oxidation in the kidney of high fructose-fed rats15
Mitochondrial angiotensin II receptors regulate oxygen consumption in kidney mitochondria from healthy and type 1 diabetic rats15
Juvenile OLFM4-null mice are protected from sepsis15
(Pro)renin receptor decoy peptide PRO20 protects against adriamycin-induced nephropathy by targeting the intrarenal renin-angiotensin system15
Intratubular epithelial-mesenchymal transition and tubular atrophy after kidney injury in mice15
Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease15
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes15
Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney disease15
Metabolic reprogramming in a slowly developing orthologous model of polycystic kidney disease15
Soluble (pro)renin receptor promotes the fibrotic response in renal proximal tubule epithelial cells in vitro via the Akt/β-catenin/Snail signaling pathway15
RNA-Seq profiling of microdissected glomeruli identifies potential biomarkers for human IgA nephropathy15
HIF-1α is transcriptionally regulated by NF-κB in acute kidney injury15
GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in prehypertensive rats15
1,3-Butanediol attenuates hypertension and suppresses kidney injury in female rats15
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved15
Kidney-specific KO of the circadian clock protein PER1 alters renal Na+ handling, aldosterone levels, and kidney/adrenal gene expression14
Effects of a CCR2 antagonist on macrophages and Toll-like receptor 9 expression in a mouse model of diabetic nephropathy14
Natural antibody and complement activation characterize patients with idiopathic nephrotic syndrome14
Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy14
Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced kidney injury14
Testosterone modulates renal ammonia metabolism14
Protein arginine methyltransferase 1 mediates renal fibroblast activation and fibrogenesis through activation of Smad3 signaling14
Differential kidney proximal tubule cell responses to protein overload by albumin and its ligands14
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin14
Lipotoxicity dysregulates the immunoproteasome in podocytes and kidneys in type 2 diabetes14
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease14
Rab7 involves Vps35 to mediate AQP2 sorting and apical trafficking in collecting duct cells14
Sox6 as a new modulator of renin expression in the kidney14
Elucidation of cGMP-dependent induction of mitochondrial biogenesis through PKG and p38 MAPK in the kidney14
Cosmc-dependent mucin-typeO-linked glycosylation is essential for podocyte function14
Protective effect of d-alanine against acute kidney injury14
Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats13
Role of SIRT1 in HIV-associated kidney disease13
MiR-21 promotes calcium oxalate-induced renal tubular cell injury by targeting PPARA13
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury13
Nonesterified free fatty acids enhance the inflammatory response in renal tubules by inducing extracellular ATP release13
High-protein diet accelerates diabetes and kidney disease in the BTBRob/ob mouse13
Western diet induces renal artery endothelial stiffening that is dependent on the epithelial Na+ channel13
Renal lymphatic vessel dynamics13
Role of the polycystins as mechanosensors of extracellular stiffness13
IL-10 treatment decreases blood pressure in male, but not female, spontaneously hypertensive rats13
Dual blockade of protease-activated receptor 1 and 2 additively ameliorates diabetic kidney disease13
CBX7 suppression prevents ischemia-reperfusion injury-induced endoplasmic reticulum stress through the Nrf-2/HO-1 pathway13
AMP-activated protein kinase contributes to cisplatin-induced renal epithelial cell apoptosis and acute kidney injury13
Phosphorylation of key podocyte proteins and the association with proteinuric kidney disease13
Angiotensin type 2 receptor activation limits kidney injury during the early phase and induces Treg cells during the late phase of renal ischemia13
Aldosterone-dependent and -independent regulation of Na+and K+excretion and ENaC in mouse kidneys13
Autoimmunity to urothelial antigen causes bladder inflammation, pelvic pain, and voiding dysfunction: a novel animal model for Hunner-type interstitial cystitis13
Renal ischemia alters expression of mitochondria-related genes and impairs mitochondrial structure and function in swine scattered tubular-like cells13
Zebrafish (Danio rerio) larva as an in vivo vertebrate model to study renal function13
Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats13
Localization of angiotensin II type 1 receptor gene expression in rodent and human kidneys13
Involvement of the CDKL5-SOX9 signaling axis in rhabdomyolysis-associated acute kidney injury13
G protein-coupled estrogen receptor 1 as a novel regulator of blood pressure13
Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension12
Fibroblast growth factor 23 leads to endolysosomal routing of the renal phosphate cotransporters NaPi-IIa and NaPi-IIc in vivo12
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury12
Inhaled silica nanoparticles cause chronic kidney disease in rats12
Protein kinase A catalytic-α and catalytic-β proteins have nonredundant regulatory functions12
Beyond the tubule: pathological variants of LRP2, encoding the megalin receptor, result in glomerular loss and early progressive chronic kidney disease12
Deletion of renal Nedd4-2 abolishes the effect of high sodium intake (HS) on Kir4.1, ENaC, and NCC and causes hypokalemia during high HS12
Nicotine, smoking, podocytes, and diabetic nephropathy12
CD4+ T cells cause renal and placental mitochondrial oxidative stress as mechanisms of hypertension in response to placental ischemia12
Effect of sex differences in treatment response to angioplasty in a murine arteriovenous fistula model12
Endothelial cells: potential novel regulators of renal inflammation12
Bayesian identification of candidate transcription factors for the regulation of Aqp2 gene expression12
Gene expression profiling of proximal and distal renal tubules in Atlantic salmon (Salmo salar) acclimated to fresh water and seawater12
Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells12
Expression and function of human ribonuclease 4 in the kidney and urinary tract12
High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults12
A new view of macula densa cell microanatomy12
Effects of long-term intradialytic oral nutrition and exercise on muscle protein homeostasis and markers of mitochondrial content in patients on hemodialysis12
Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of diabetic nephropathy in BTBR ob/ob mice11
A two-stage bilateral ischemia-reperfusion injury-induced AKI to CKD transition model in mice11
Time-dependent progression of neurogenic lower urinary tract dysfunction after spinal cord injury in the mouse model11
Chemokine CCL2 from proximal tubular epithelial cells contributes to sepsis-induced acute kidney injury11
Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats11
Role of the renal androgen receptor in sex differences in ammonia metabolism11
Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance11
Physiology assays in human kidney organoids11
Deletion of Kir5.1 abolishes the effect of high Na+ intake on Kir4.1 and Na+-Cl cotransporter11
IFT88 deficiency in proximal tubular cells exaggerates cisplatin-induced injury by suppressing autophagy11
Cleavage state of γENaC in mouse and rat kidneys11
Differential localization patterns of claudin 10, 16, and 19 in human, mouse, and rat renal tubular epithelia11
Antibiotic-induced microbiome depletion alters renal glucose metabolism and exacerbates renal injury after ischemia-reperfusion injury in mice11
Blockade of STAT3 signaling alleviates the progression of acute kidney injury to chronic kidney disease through antiapoptosis11
Intracellular location of aquaporin-2 serine 269 phosphorylation and dephosphorylation in kidney collecting duct cells11
Circadian variation in renal blood flow and kidney function in healthy volunteers monitored with noninvasive magnetic resonance imaging11
Metformin ameliorates bladder dysfunction in a rat model of partial bladder outlet obstruction11
Inhibition of 15-PGDH prevents ischemic renal injury by the PGE2/EP4signaling pathway mediating vasodilation, increased renal blood flow, and increased adenosine/A2Are11
Decreased IFT88 expression with primary cilia shortening causes mitochondrial dysfunction in cisplatin-induced tubular injury11
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na+ channel in the mouse kidney10
PF-06869206 is a selective inhibitor of renal Pitransport: evidence from in vitro and in vivo studies10
Inward Ca2+ current through the polycystin-2-dependent channels of renal primary cilia10
A uropathogenic E. coli UTI89 model of prostatic inflammation and collagen accumulation for use in studying aberrant collagen production in the prostate10
Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression10
Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development10
Landscape of GPCR expression along the mouse nephron10
Protective role of DJ-1 in endotoxin-induced acute kidney injury10
L-WNK1 is required for BK channel activation in intercalated cells10
Combinatorial expression of claudins in the proximal renal tubule and its functional consequences10
Hypertensive female Sprague-Dawley rats require an intact nitric oxide synthase system for compensatory increases in renal regulatory T cells10
Chronic unilateral cervical vagotomy reduces renal inflammation, blood pressure, and renal injury in a mouse model of lupus10
Acidosis induces antimicrobial peptide expression and resistance to uropathogenic E. coli infection in kidney collecting duct cells via HIF-1α10
Pendrin-null mice develop severe hypokalemia following dietary Na+ and K+ restriction: role of ENaC10
Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells10
Aristolochic acid-induced nephropathy is attenuated in mice lacking the neutral amino acid transporter B0AT1 (Slc6a19)10
Mitochondria as mediators of systemic inflammation and organ cross talk in acute kidney injury10
WNK4 kinase: from structure to physiology10
Mutation of RORγT reveals a role for Th17 cells in both injury and recovery from renal ischemia-reperfusion injury10
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