American Journal of Physiology-Renal Physiology

(The TQCC of American Journal of Physiology-Renal Physiology is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-06-01 to 2023-06-01.)
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury476
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation256
Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells209
Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium152
Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy150
Immunity and inflammation in diabetic kidney disease: translating mechanisms to biomarkers and treatment targets148
Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition147
Urea and urine concentrating ability: new insights from studies in mice146
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury145
Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis132
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition130
Loop diuretics: from the Na-K-2Cl transporter to clinical use130
Bladder permeability barrier: recovery from selective injury of surface epithelial cells125
Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human123
Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression122
ATP is released from guinea pig ureter epithelium on distension118
MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals118
Renal function measurements from MR renography and a simplified multicompartmental model113
Cold ischemic injury of transplanted kidneys: new insights from experimental studies112
Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells107
Angiotensin II releases 20-HETE from rat renal microvessels106
The organic anion transporter family: from physiology to ontogeny and the clinic100
Chronic kidney disease and the gut microbiome100
Cyclophilin D gene ablation protects mice from ischemic renal injury99
Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF99
A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function97
Protection of renal cells from cisplatin toxicity by cell cycle inhibitors95
Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from aPkd1-deletion model95
Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes93
Recent insights into diabetic renal injury from thedb/dbmouse model of type 2 diabetic nephropathy93
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys93
An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse90
Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury89
Empagliflozin attenuates diabetic tubulopathy by improving mitochondrial fragmentation and autophagy88
Poly(ADP-ribose) polymerase-1 gene ablation protects mice from ischemic renal injury86
Exercise interventions for improving objective physical function in patients with end-stage kidney disease on dialysis: a systematic review and meta-analysis86
Estrogen protects renal endothelial barrier function from ischemia-reperfusion in vitro and in vivo86
Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium83
Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury79
Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure78
TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct78
Divalent cation transport by the distal nephron: insights from Bartter's and Gitelman's syndromes77
Functional TRP and ASIC-like channels in cultured urothelial cells from the rat77
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney76
Drainage of interstitial fluid from different regions of rat brain75
Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury75
SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT174
Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat74
Transforming growth factor-β in acute renal failure: receptor expression, effects on proliferation, cellularity, and vascularization after recovery from injury74
Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts73
Cloning and functional expression of rNBC, an electrogenic Na+- HCO 3 − cotransporter from rat kidney72
Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats71
Dietary oxalate and kidney stone formation68
BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury66
Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells65
Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts65
Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways61
Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions60
Efflux of radiolabeled polyethylene glycols and albumin from rat brain60
Conditionally immortalized human podocyte cell lines established from urine58
Expression and distribution of PIEZO1 in the mouse urinary tract58
Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder55
Aquaporin-2 abundance in the renal collecting duct: new insights from cultured cell models54
Divergent effects of AKI to CKD models on inflammation and fibrosis54
Branching ducts similar to mesonephric ducts or ureteric buds in teratomas originating from mouse embryonic stem cells54
Sex differences in diabetes and kidney disease: mechanisms and consequences54
IL-17 mediates neutrophil infiltration and renal fibrosis following recovery from ischemia reperfusion: compensatory role of natural killer cells in athymic rats53
Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury53
Glycolysis inhibitors suppress renal interstitial fibrosis via divergent effects on fibroblasts and tubular cells52
Interaction between uric acid and HMGB1 translocation and release from endothelial cells51
Inhibition of HDAC6 protects against rhabdomyolysis-induced acute kidney injury51
SIRT1-mediated HMGB1 deacetylation suppresses sepsis-associated acute kidney injury51
Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis51
FGF23 from bench to bedside51
Transfer of lymphocytes from mice with renal ischemia can induce albuminuria in naive mice: a possible mechanism linking early injury and progressive renal disease?50
Heat shock protein 90-binding agents protect renal cells from oxidative stress and reduce kidney ischemia-reperfusion injury49
Targeting STAT3 signaling in kidney disease47
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice47
MicroRNA-150 deletion in mice protects kidney from myocardial infarction-induced acute kidney injury47
Macrophage-secreted TGF-β1 contributes to fibroblast activation and ureteral stricture after ablation injury47
Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice47
Evaluation of cellular plasticity in the collecting duct during recovery from lithium-induced nephrogenic diabetes insipidus46
Identification of the functional domain of p21WAF1/CIP1that protects cells from cisplatin cytotoxicity46
Decreased amiloride-sensitive Na+absorption in collecting duct principal cells isolated from BPK ARPKD mice46
Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations45
Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis45
Cholinergic-induced Ca2+ signaling in interstitial cells of Cajal from the guinea pig bladder45
Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats45
Angiotensin II increases fibronectin and collagen I through the β-catenin-dependent signaling in mouse collecting duct cells45
Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension45
Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport43
Silencing of long noncoding RNA XIST protects against renal interstitial fibrosis in diabetic nephropathy via microRNA-93-5p-mediated inhibition of CDKN1A43
Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: evidence from vesicle studies43
Incomplete distal renal tubular acidosis from a heterozygous mutation of the V-ATPase B1 subunit43
Chloride channels in the kidney: lessons learned from knockout animals43
A mathematical model of diffusional shunting of oxygen from arteries to veins in the kidney42
Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis42
Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis42
Effect of renal tubule-specific knockdown of the Na+/H+exchanger NHE3 in Akita diabetic mice41
The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase41
Identification and characterization of a glomerular-specific promoter from the human nephrin gene41
Transepithelial HCO3 absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice41
Extracellular microRNA signature in chronic kidney disease39
Renal anemia: from incurable to curable39
Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis38
“I don’t get no respect”: the role of chloride in acute kidney injury38
Sleeping beauty: awakening urothelium from its slumber38
AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys38
5-Aminolevulinic acid combined with ferrous iron induces carbon monoxide generation in mouse kidneys and protects from renal ischemia-reperfusion injury38
Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis38
Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKα isoforms37
Renal autoregulation: perspectives from whole kidney and single nephron studies37
Clusterin protects renal tubular epithelial cells from gentamicin-mediated cytotoxicity36
Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injury36
Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age36
Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats36
Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K+excretion36
p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication35
Inflammation drives renal scarring in experimental pyelonephritis35
ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice35
Effects of cell Ca and pH on Na channels from rat cortical collecting tubule35
Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease35
Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent35
Coupled ATP and potassium efflux from intercalated cells35
Sex and gender differences in hypertensive kidney injury35
p38 Mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury34
ROCK2 regulates TGF-β-induced expression of CTGF and profibrotic genes via NF-κB and cytoskeleton dynamics in mesangial cells34
Periostin induces kidney fibrosis after acute kidney injury via the p38 MAPK pathway34
Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide34
Chronic effects of repeated low-dose cisplatin treatment in mouse kidneys and renal tubular cells34
Role of ADAM17 in kidney disease33
Effects of aerobic exercise on vascular function in nondialysis chronic kidney disease: a randomized controlled trial33
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat32
LC-MS/MS analysis of differential centrifugation fractions from native inner medullary collecting duct of rat32
Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration32
Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure32
Characterization of a type IIb sodium-phosphate cotransporter from zebrafish(Danio rerio)kidney32
Urinary microRNA in kidney disease: utility and roles32
Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients31
Prohibitin 2-mediated mitophagy attenuates renal tubular epithelial cells injury by regulating mitochondrial dysfunction and NLRP3 inflammasome activation31
A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on “single-cell”-specific KO model of the distal nephron31
Partial podocyte replenishment in experimental FSGS derives from nonpodocyte sources30
Progression of diabetic kidney disease in T2DN rats30
Ionic currents and endothelin signaling in smooth muscle cells from rat renal resistance arteries30
Proteomic analysis of brush-border membrane vesicles isolated from purified proximal convoluted tubules30
Capillary rarefaction is more closely associated with CKD progression after cisplatin, rhabdomyolysis, and ischemia-reperfusion-induced AKI than renal fibrosis30
Memories that last in hypertension29
Zinc deficiency induces hypertension by promoting renal Na+ reabsorption29
Urea protects from the proapoptotic effect of NaCl in renal medullary cells29
Deletion of Frs2α from the ureteric epithelium causes renal hypoplasia29
AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation29
LPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis29
Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice29
Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function29
Absence of aquaporin-4 water channels from kidneys of the desert rodentDipodomys merriami merriami28
Arteriovenous conduits for hemodialysis: how to better modulate the pathophysiological vascular response to optimize vascular access durability28
Macrophage polarization in chronic kidney disease: a balancing act between renal recovery and decline?28
Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression28
Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells28
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate28
GLP-1 receptor agonists in diabetic kidney disease: from the patient-side to the bench-side28
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent28
Unraveling reno-protective effects of SGLT2 inhibition in human proximal tubular cells28
Molecular characterization of a novel urea transporter from kidney inner medullary collecting ducts27
Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats26
Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model26
Acute increases of renal medullary osmolality stimulate endothelin release from the kidney26
Urine citrate excretion identifies changes in acid retention as eGFR declines in patients with chronic kidney disease26
Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI26
Elevated serum anion gap in adults with moderate chronic kidney disease increases risk for progression to end-stage renal disease26
Genetics of hypertension: discoveries from the bench to human populations25
Mitochondrial activity contributes to impaired renal metabolic homeostasis and renal pathology in STZ-induced diabetic mice25
Angiotensin-converting enzyme inhibition aggravates renal interstitial injury resulting from partial unilateral ureteral obstruction in the neonatal rat25
Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers25
Blockade of sodium-glucose cotransporter 2 suppresses high glucose-induced angiotensinogen augmentation in renal proximal tubular cells25
Salt-sensitive increase in macrophages in the kidneys of Dahl SS rats25
Mechanotransduction signaling in podocytes from fluid flow shear stress25
Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways25
Morg1 heterozygous mice are protected from acute renal ischemia-reperfusion injury25
Vasopressin/V2 receptor stimulates renin synthesis in the collecting duct25
Path of translational discovery of urological complications of obesity and diabetes25
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1cells25
Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct25
Ureteric bud cells secrete multiple factors, including bFGF, which rescue renal progenitors from apoptosis24
Molecular cloning, chromosomal organization, and functional characterization of a sodium-dicarboxylate cotransporter from mouse kidney24
Obesity causes renal mitochondrial dysfunction and energy imbalance and accelerates chronic kidney disease in mice24
Escape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct24
Angiotensin II-induced calcium signaling in the afferent arteriole from rats with two-kidney, one-clip hypertension24
Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy24
Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice24
Clonal sublines that are morphologically and functionally distinct from parental OK cells24
Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia24
Complement C3 exacerbates renal interstitial fibrosis by facilitating the M1 macrophage phenotype in a mouse model of unilateral ureteral obstruction23
Angiotensin blocks substance P release from renal sensory nerves by inhibiting PGE2-mediated activation of cAMP23
Circadian variation in the release of small extracellular vesicles can be normalized by vesicle number or TSG10123
Altered V-ATPase expression in renal intercalated cells isolated from B1 subunit-deficient mice by fluorescence-activated cell sorting23
Identification of novel metabolomic biomarkers in an experimental model of septic acute kidney injury23
Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis23
Molecular and functional characterization of a urea transporter from the kidney of the Atlantic stingray23
Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury23
Suramin protects from cisplatin-induced acute kidney injury22
Alterations in cell-adhesive and migratory properties of proximal tubule and collecting duct cells from bcl-2 −/− mice22
The protective effect of klotho against contrast-associated acute kidney injury via the antioxidative effect22
Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids22
Early podocyte injury and elevated levels of urinary podocyte-derived extracellular vesicles in swine with metabolic syndrome: role of podocyte mitochondria22
PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death22
Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion22
Enhanced ammonia secretion by proximal tubules from mice receiving NH4Cl: role of angiotensin II21
Reduced endothelial nitric oxide synthase activation contributes to cardiovascular injury during chronic kidney disease progression21
Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-γ-miR-23 axis21
Direct and indirect inhibition of the circadian clock protein Per1: effects on ENaC and blood pressure21
Anion exchanger 1 in human kidney and oncocytoma differs from erythroid AE1 in its NH2 terminus21
Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation21
Characterizing novel olfactory receptors expressed in the murine renal cortex21
Recent advances in sex differences in kidney function21
Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers21
Ammonia production and secretion by S3 proximal tubule segments from acidotic mice: role of ANG II21
Renal tubular effects of prolonged therapy with the GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes mellitus21
TGF-β1 modifies histone acetylation and acetyl-coenzyme A metabolism in renal myofibroblasts21
A zebrafish model of infection-associated acute kidney injury21