American Journal of Physiology-Renal Physiology

Article	Citations
First Author Highlights	57
Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation	43
Expression of leptin receptor in renal tubules is sparse but implicated in leptin-dependent kidney gene expression and function	41
Corrigendum for Jang et al., volume 326, 2024, p. F69	40
First Author Highlights	40
First Author Highlights	40
Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth	38
Exercise sensitizes the pressure diuresis response: shifting immune landscapes may underlie renal adaptations	35
Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats	33
C-terminal fragment of fibroblast growth factor 23 improves heart function in murine models of high intact fibroblast growth factor 23	31
“Idiopathic” minimal change nephrotic syndrome: a podocyte mystery nears the end	29
Perinatal asphyxia leads to acute kidney damage and increased renal susceptibility in adulthood	29
Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male Sprague-Dawley rats	29
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism	28
A mathematical model of the rat kidney. IV. Whole kidney response to hyperkalemia	28
Role of the CDKL1-SOX11 signaling axis in acute kidney injury	28
Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species	28
Interleukin-6 blockade reduces salt-induced cardiac inflammation and fibrosis in subtotal nephrectomized mice	27
Polygenic genetic variation affecting antibody formation underlies hypertensive renal injury in the stroke-prone spontaneously hypertensive rat	26
First Author Highlights	26
Defining protein expression in the kidney at large scale: from antibody validation to cytometry analysis	25
β2-Adrenergic receptor agonists: a new treatment for diabetic kidney disease?	25
Perspective on G protein-coupled receptors in renal physiology	24
A brief history of the cortical thick ascending limb: a systems-biology perspective	24
Pax inhibition: stressing proximal tubule for successful repair	24

Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury	22
SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy	22
Redox regulation in diabetic kidney disease	21
Splenocyte transfer from hypertensive donors eliminates premenopausal female protection from ANG II-induced hypertension	21
Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease	20
A key role of AT1a receptors and Na+/H+ exchanger 3 in the proximal tubules in angiotensin II-induced and two-kidney, one-clip Goldblatt hypertension	20
A combination of β-hydroxybutyrate and citrate ameliorates disease progression in a rat model of polycystic kidney disease	19
The nephronophthisis protein GLIS2 / NPHP7 is required for the DNA damage response in kidney tubular epith	19
Methylseq, single-nuclei RNAseq, and discovery proteomics identify pathways associated with nephron-deficit CKD in the HSRA rat model	19
Activation of branched chain amino acid catabolism protects against nephrotoxic acute kidney injury	19
Renal cell markers: lighthouses for managing renal diseases	18
Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing	18
Hyperphosphatemia and zinc deficiency in chronic kidney disease: unpacking their interconnected roles and nutritional implications	18
Novel insight on physiological regulation of the Cl−/HCO3− exchanger pendrin	17
Cilia-deficient renal tubule cells are primed for injury with mitochondrial defects and aberrant tryptophan metabolism	17
Race and sex differences in pressor response to laboratory stressors in patients with chronic kidney disease	17
Angiotensin in the acute and chronic responses to unilateral nephrectomy	17
15-Lipoxygenase worsens renal fibrosis, inflammation, and metabolism in a murine model of ureteral obstruction	17
First Author Highlights	17
Dysregulation of the sensory and regulatory pathways controlling cellular iron metabolism in unilateral obstructive nephropathy	17
Valosin-containing protein in ciliary morphology: a novel target in ADPKD	17
Ubiquitination of NKCC2 by the cullin-RING E3 ubiquitin ligase family in the thick ascending limb of the loop of Henle	16
Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy	16
Delayed graft function post renal transplantation: a review on animal models and therapeutics	16
Editorial Board	16
Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats	16
Prolonged unilateral renal ischemia-reperfusion as a model for acute to chronic kidney injury in female mice	16
Long-term follow-up of TREK-1 KO mice reveals the development of bladder hypertrophy and impaired bladder smooth muscle contractility with age	16
Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase	16
Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction	16
Corrigendum for Fu et al., volume 317, 2019, p. F1582–F1592	15
First Author Spotlight	15
Investigating FSGS-like injury in zebrafish larvae by nifurpirinol: efficacy and molecular insight	14
Commensal microbiota regulate aldosterone	14
Characterization of FAM114A1: a novel podocyte cytoskeleton-associated protein upregulated in glomerular injury	14
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice	14
High dietary K+ intake inhibits proximal tubule transport	14
Metformin reduces insulin resistance and attenuates progressive renal injury in prepubertal obese Dahl salt-sensitive rats	14
Macrophage angiotensin AT2 receptor activation is protective against early phases of LPS-induced acute kidney injury	13
Influence of proteolytic cleavage of ENaC’s γ subunit upon Na+ and K+ handling	13
First Author Spotlight	13
Mapping single-nephron filtration in the isolated, perfused rat kidney using magnetic resonance imaging	13
High baseline ROMK activity in the mouse late distal convoluted and early connecting tubule probably contributes to aldosterone-independent K+ secretion	13
Recent advances in understanding the kidney circadian clock mechanism	13
Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease	13
Downloadable Tool for Modeling of Salt, Urea and Water Transport in a Renal Tubule Segment: Application to the DCT	13
A novel functional role for the classic CNS neurotransmitters, GABA, glycine, and glutamate, in the kidney: potent and opposing regulators of the renal vasculature	13
Inducible Avp knockout mouse line	13
Impaired nitric oxide mechanisms underlying lower urinary tract dysfunction in aging rats	13
Revisiting voltage-coupled H+ secretion in the collecting duct	13

The kidney in health and disease in 2022: Gaps in and opportunities for new knowledge	13
First Author Spotlight	13
Physiology assays in human kidney organoids	12
Inducible deletion of the prostaglandin EP3 receptor in kidney tubules of male and female mice has no major effect on water homeostasis	12
Kidney transplant injury associated with brain death is mediated by TNFα, independently of renal innervation	12
TNIK depletion induces inflammation and apoptosis in injured renal proximal tubule epithelial cells	12
Angiotensin II-stimulated proximal nephron superoxide production and fructose-induced salt-sensitive hypertension	12
Ad Libitum Drinking Does Not Mitigate Acute Kidney Injury Risk nor Elevations in Oxidative Stress or Inflammation during Simulated Occupational Heat Stress	12
Intersecting transcriptomic landscapes of hypertension and kidney function in African American women	12
Sex-disaggregated analysis of acute kidney injury in hospitalized children with sickle cell anemia in Uganda	12
Sex differences in dietary sodium evoked NCC regulation and blood pressure in male and female Sprague-Dawley, Dahl salt-resistant, and Dahl salt-sensitive rats	12
Sex differences in renal acid-base regulation	12
Pendrin regulation is prioritized by anion in high-potassium diets	12
5-Hydroxytryptamine 1F receptor loss reduces renal vasculature and prevents lasmiditan-induced recovery following moderate-severe acute kidney injury in mice	12
Kir4.1/Kir5.1 of distal convoluted tubule is required for short-term angiotensin-II-induced stimulation of Na-Cl cotransporter	12
The impact of maternal obesity on polycystic kidney disease progression in a mouse model	12
Impaired hemodynamic renal reserve response following recovery from established acute kidney injury and improvement by hydrodynamic isotonic fluid delivery	12
JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice	11
Amiloride lowers plasma TNF and interleukin-6 but not interleukin-17A in patients with hypertension and type 2 diabetes	11
A brief harvesting-freezing delay significantly alters the kidney metabolome and leads to false positive and negative results	11
Prevention of hypertension-induced renal vascular dysfunction through a p66Shc-targeted mechanism	11
Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis	11
Exogenous pericyte delivery protects the mouse kidney from chronic ischemic injury	11
Parental obesity predisposes offspring to kidney dysfunction and increased susceptibility to ischemia-reperfusion injury in a sex-dependent manner	11
Insulin-regulated aminopeptidase is required for water excretion in response to acute hypotonic stress	11
Practical notes on popular statistical tests in renal physiology	11
Collectrin (Tmem27) deficiency in proximal tubules causes hypertension in mice and a TMEM27 variant associates with blood pressure in males in a Latino cohort	11
CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes	11
Furin-mediated modification is required for epithelial sodium channel-activating activity of soluble (pro)renin receptor in cultured collecting duct cells	11
Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation: implications for glomerular hemodynamics	11
Injury in nonaged podocytes as an accelerator of glomerular aging	11
Chronic kidney disease amplifies severe kidney injury and mortality in a mouse model of skin arsenical exposure	11
Regulation of kidney mitochondrial function by caloric restriction	11
Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients	10
Bayesian mapping of protein kinases to vasopressin-regulated phosphorylation sites in renal collecting duct	10
Exogenous uromodulin and tubular responses in a model of oxalate-induced kidney injury	10
Mechanisms of anti-VEGF therapy-induced kidney injury: current insights and future perspectives in combination with immune checkpoint inhibitors	10
Editorial Board	10
HMGB1 drives T-cell activation in hypertensive males and females	10
Male Akita mice develop signs of bladder underactivity independent of NLRP3 as a result of a decrease in neurotransmitter release from efferent neurons	10
Altered renal vascular patterning reduces ischemic kidney injury and limits age-associated vascular loss	10
The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in the human kidney	10
Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury	10
First Author Highlights	10
Maresin 1 Modulates Renal and Cardiac Lipid Profiles in Hypertensive Rats	10
Promises and challenges of miRNA therapeutics	10
Macrophage SPAK deletion limits a low potassium-induced kidney inflammatory program	9
Novel method for kinetic analysis applied to transport by the uniporter OCT2	9
Creatinine clearance is maintained in a range of wet-bulb globe temperatures and work-rest ratios during simulated occupational heat stress	9
The miR-143/145 cluster induced by TGF-β1 suppresses Wilms’ tumor 1 expression in cultured human podocytes	9
Postoperative acute kidney injury after volatile or intravenous anesthesia: a meta-analysis	9
Adverse functions of neutrophils are regulated by neutrophilic angiotensin-converting enzyme in immune complex-mediated crescentic glomerulonephritis	9
IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage	9
Mitochondrial dysfunction in the pathophysiology of renal diseases	9
Flow-dependent transport processes 2024: filtration, absorption, secretion	9
The nonsteroidal MR antagonist finerenone reverses Western diet-induced kidney disease by regulating mitochondrial and lipid metabolism and inflammation	9
β2-Adrenergic receptor agonists as a treatment for diabetic kidney disease	9
Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury	9
First Author Highlights	9
Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity	9
Macrophages and TGFB Signaling Regulate Fibrosis in the E. coli -Infected Mouse Prostate	9
Nicotinamide ameliorates podocyte injury and albuminuria in adriamycin-induced nephropathy	9
Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation	8
Fasting-induced HMGCS2 expression in the kidney does not contribute to circulating ketones	8
Chronic central nervous system leptin administration attenuates kidney dysfunction and injury in a model of ischemia/reperfusion-induced acute kidney injury	8
Western diet exacerbates a murine model of Balkan nephropathy	8
Corrigendum for Martínez-Rojas et al., volume 323, 2022, p. F425–F434	8
Pathways and parameters of sacral neuromodulation in rats	8
Kidney functional reserve helps early detection of subclinical chronic kidney disease	8
Role of protease-activated receptor 4 in mouse models of acute and chronic kidney injury	8
Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance	8
First Author Spotlight	8
Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice	8
High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults	8
Corrigendum for McKinzie et al., volume 326, 2024, p. F644–F660	8
2024 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section	8
KCC3 is not required for the distal convoluted tubule response to reduced dietary potassium intake	8
First Author Highlights	8
Endothelin-1 signaling in the kidney: recent advances and remaining gaps	8
Renal tubular (pro)renin receptor deletion exacerbates kidney injury in db/db mice	8

Tacrolimus induces fibroblast-to-myofibroblast transition via a TGF-β-dependent mechanism to contribute to renal fibrosis	8
Transcription factor HNF1β controls a transcriptional network regulating kidney cell structure and tight junction integrity	8
Assays to enhance metabolic phenotyping in the kidney	8
Predicting sex differences in the effects of diuretics in renal epithelial transport during angiotensin II-induced hypertension	8
Divergent roles of angiotensin II upon the immediate and sustained increases of renal blood flow following unilateral nephrectomy	8
The knock-out of paracingulin attenuates hypertension through modulation of kidney ion transport	8
Editorial Board	8
The role of Gata3 in renin cell identity	8
Chronic circadian stress impairs blood pressure and sodium homeostasis in a diet- and sex-specific manner	8
The degree of aortic occlusion in the setting of trauma alters the extent of acute kidney injury associated with mitochondrial preservation	8
Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease	8
Longitudinal intravital microscopy of the mouse kidney: inflammatory responses to abdominal imaging windows	8