American Journal of Physiology-Renal Physiology

Article	Citations
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury	476
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation	256
Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells	209
Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium	152
Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy	150
Immunity and inflammation in diabetic kidney disease: translating mechanisms to biomarkers and treatment targets	148
Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition	147
Urea and urine concentrating ability: new insights from studies in mice	146
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury	145
Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis	132
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition	130
Loop diuretics: from the Na-K-2Cl transporter to clinical use	130
Bladder permeability barrier: recovery from selective injury of surface epithelial cells	125
Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human	123
Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression	122
ATP is released from guinea pig ureter epithelium on distension	118
MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals	118
Renal function measurements from MR renography and a simplified multicompartmental model	113
Cold ischemic injury of transplanted kidneys: new insights from experimental studies	112
Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells	107
Angiotensin II releases 20-HETE from rat renal microvessels	106
The organic anion transporter family: from physiology to ontogeny and the clinic	100
Chronic kidney disease and the gut microbiome	100
Cyclophilin D gene ablation protects mice from ischemic renal injury	99
Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF	99

A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function	97
Protection of renal cells from cisplatin toxicity by cell cycle inhibitors	95
Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from aPkd1-deletion model	95
Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes	93
Recent insights into diabetic renal injury from thedb/dbmouse model of type 2 diabetic nephropathy	93
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys	93
An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse	90
Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury	89
Empagliflozin attenuates diabetic tubulopathy by improving mitochondrial fragmentation and autophagy	88
Poly(ADP-ribose) polymerase-1 gene ablation protects mice from ischemic renal injury	86
Exercise interventions for improving objective physical function in patients with end-stage kidney disease on dialysis: a systematic review and meta-analysis	86
Estrogen protects renal endothelial barrier function from ischemia-reperfusion in vitro and in vivo	86
Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium	83
Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury	79
Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure	78
TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct	78
Divalent cation transport by the distal nephron: insights from Bartter's and Gitelman's syndromes	77
Functional TRP and ASIC-like channels in cultured urothelial cells from the rat	77
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney	76
Drainage of interstitial fluid from different regions of rat brain	75
Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury	75
SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1	74
Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat	74
Transforming growth factor-β in acute renal failure: receptor expression, effects on proliferation, cellularity, and vascularization after recovery from injury	74
Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts	73
Cloning and functional expression of rNBC, an electrogenic Na+- HCO 3 − cotransporter from rat kidney	72
Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats	71
Dietary oxalate and kidney stone formation	68
BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury	66
Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells	65
Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts	65
Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways	61
Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions	60
Efflux of radiolabeled polyethylene glycols and albumin from rat brain	60
Conditionally immortalized human podocyte cell lines established from urine	58
Expression and distribution of PIEZO1 in the mouse urinary tract	58
Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder	55
Aquaporin-2 abundance in the renal collecting duct: new insights from cultured cell models	54
Divergent effects of AKI to CKD models on inflammation and fibrosis	54
Branching ducts similar to mesonephric ducts or ureteric buds in teratomas originating from mouse embryonic stem cells	54
Sex differences in diabetes and kidney disease: mechanisms and consequences	54
IL-17 mediates neutrophil infiltration and renal fibrosis following recovery from ischemia reperfusion: compensatory role of natural killer cells in athymic rats	53
Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury	53
Glycolysis inhibitors suppress renal interstitial fibrosis via divergent effects on fibroblasts and tubular cells	52
Interaction between uric acid and HMGB1 translocation and release from endothelial cells	51
Inhibition of HDAC6 protects against rhabdomyolysis-induced acute kidney injury	51
SIRT1-mediated HMGB1 deacetylation suppresses sepsis-associated acute kidney injury	51
Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis	51
FGF23 from bench to bedside	51
Transfer of lymphocytes from mice with renal ischemia can induce albuminuria in naive mice: a possible mechanism linking early injury and progressive renal disease?	50

Heat shock protein 90-binding agents protect renal cells from oxidative stress and reduce kidney ischemia-reperfusion injury	49
Targeting STAT3 signaling in kidney disease	47
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice	47
MicroRNA-150 deletion in mice protects kidney from myocardial infarction-induced acute kidney injury	47
Macrophage-secreted TGF-β1 contributes to fibroblast activation and ureteral stricture after ablation injury	47
Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice	47
Evaluation of cellular plasticity in the collecting duct during recovery from lithium-induced nephrogenic diabetes insipidus	46
Identification of the functional domain of p21WAF1/CIP1that protects cells from cisplatin cytotoxicity	46
Decreased amiloride-sensitive Na+absorption in collecting duct principal cells isolated from BPK ARPKD mice	46
Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations	45
Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis	45
Cholinergic-induced Ca2+ signaling in interstitial cells of Cajal from the guinea pig bladder	45
Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats	45
Angiotensin II increases fibronectin and collagen I through the β-catenin-dependent signaling in mouse collecting duct cells	45
Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension	45
Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport	43
Silencing of long noncoding RNA XIST protects against renal interstitial fibrosis in diabetic nephropathy via microRNA-93-5p-mediated inhibition of CDKN1A	43
Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: evidence from vesicle studies	43
Incomplete distal renal tubular acidosis from a heterozygous mutation of the V-ATPase B1 subunit	43
Chloride channels in the kidney: lessons learned from knockout animals	43
A mathematical model of diffusional shunting of oxygen from arteries to veins in the kidney	42
Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis	42
Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis	42
Effect of renal tubule-specific knockdown of the Na+/H+exchanger NHE3 in Akita diabetic mice	41
The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase	41
Identification and characterization of a glomerular-specific promoter from the human nephrin gene	41
Transepithelial HCO3− absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice	41
Extracellular microRNA signature in chronic kidney disease	39
Renal anemia: from incurable to curable	39
Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis	38
“I don’t get no respect”: the role of chloride in acute kidney injury	38
Sleeping beauty: awakening urothelium from its slumber	38
AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys	38
5-Aminolevulinic acid combined with ferrous iron induces carbon monoxide generation in mouse kidneys and protects from renal ischemia-reperfusion injury	38
Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis	38
Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKα isoforms	37
Renal autoregulation: perspectives from whole kidney and single nephron studies	37
Clusterin protects renal tubular epithelial cells from gentamicin-mediated cytotoxicity	36
Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injury	36
Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age	36
Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats	36
Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K+excretion	36
p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication	35
Inflammation drives renal scarring in experimental pyelonephritis	35
ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice	35
Effects of cell Ca and pH on Na channels from rat cortical collecting tubule	35
Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease	35
Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent	35
Coupled ATP and potassium efflux from intercalated cells	35
Sex and gender differences in hypertensive kidney injury	35
p38 Mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury	34
ROCK2 regulates TGF-β-induced expression of CTGF and profibrotic genes via NF-κB and cytoskeleton dynamics in mesangial cells	34
Periostin induces kidney fibrosis after acute kidney injury via the p38 MAPK pathway	34
Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide	34
Chronic effects of repeated low-dose cisplatin treatment in mouse kidneys and renal tubular cells	34
Role of ADAM17 in kidney disease	33
Effects of aerobic exercise on vascular function in nondialysis chronic kidney disease: a randomized controlled trial	33
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat	32
LC-MS/MS analysis of differential centrifugation fractions from native inner medullary collecting duct of rat	32
Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration	32
Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure	32
Characterization of a type IIb sodium-phosphate cotransporter from zebrafish(Danio rerio)kidney	32
Urinary microRNA in kidney disease: utility and roles	32
Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients	31
Prohibitin 2-mediated mitophagy attenuates renal tubular epithelial cells injury by regulating mitochondrial dysfunction and NLRP3 inflammasome activation	31
A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on “single-cell”-specific KO model of the distal nephron	31
Partial podocyte replenishment in experimental FSGS derives from nonpodocyte sources	30
Progression of diabetic kidney disease in T2DN rats	30
Ionic currents and endothelin signaling in smooth muscle cells from rat renal resistance arteries	30
Proteomic analysis of brush-border membrane vesicles isolated from purified proximal convoluted tubules	30
Capillary rarefaction is more closely associated with CKD progression after cisplatin, rhabdomyolysis, and ischemia-reperfusion-induced AKI than renal fibrosis	30
Memories that last in hypertension	29
Zinc deficiency induces hypertension by promoting renal Na+ reabsorption	29
Urea protects from the proapoptotic effect of NaCl in renal medullary cells	29
Deletion of Frs2α from the ureteric epithelium causes renal hypoplasia	29
AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation	29
LPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis	29
Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice	29
Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function	29
Absence of aquaporin-4 water channels from kidneys of the desert rodentDipodomys merriami merriami	28

Arteriovenous conduits for hemodialysis: how to better modulate the pathophysiological vascular response to optimize vascular access durability	28
Macrophage polarization in chronic kidney disease: a balancing act between renal recovery and decline?	28
Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression	28
Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells	28
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate	28
GLP-1 receptor agonists in diabetic kidney disease: from the patient-side to the bench-side	28
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent	28
Unraveling reno-protective effects of SGLT2 inhibition in human proximal tubular cells	28
Molecular characterization of a novel urea transporter from kidney inner medullary collecting ducts	27
Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats	26
Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model	26
Acute increases of renal medullary osmolality stimulate endothelin release from the kidney	26
Urine citrate excretion identifies changes in acid retention as eGFR declines in patients with chronic kidney disease	26
Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI	26
Elevated serum anion gap in adults with moderate chronic kidney disease increases risk for progression to end-stage renal disease	26
Genetics of hypertension: discoveries from the bench to human populations	25
Mitochondrial activity contributes to impaired renal metabolic homeostasis and renal pathology in STZ-induced diabetic mice	25
Angiotensin-converting enzyme inhibition aggravates renal interstitial injury resulting from partial unilateral ureteral obstruction in the neonatal rat	25
Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers	25
Blockade of sodium-glucose cotransporter 2 suppresses high glucose-induced angiotensinogen augmentation in renal proximal tubular cells	25
Salt-sensitive increase in macrophages in the kidneys of Dahl SS rats	25
Mechanotransduction signaling in podocytes from fluid flow shear stress	25
Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways	25
Morg1 heterozygous mice are protected from acute renal ischemia-reperfusion injury	25
Vasopressin/V2 receptor stimulates renin synthesis in the collecting duct	25
Path of translational discovery of urological complications of obesity and diabetes	25
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1cells	25
Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct	25
Ureteric bud cells secrete multiple factors, including bFGF, which rescue renal progenitors from apoptosis	24
Molecular cloning, chromosomal organization, and functional characterization of a sodium-dicarboxylate cotransporter from mouse kidney	24
Obesity causes renal mitochondrial dysfunction and energy imbalance and accelerates chronic kidney disease in mice	24
Escape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct	24
Angiotensin II-induced calcium signaling in the afferent arteriole from rats with two-kidney, one-clip hypertension	24
Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy	24
Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice	24
Clonal sublines that are morphologically and functionally distinct from parental OK cells	24
Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia	24
Complement C3 exacerbates renal interstitial fibrosis by facilitating the M1 macrophage phenotype in a mouse model of unilateral ureteral obstruction	23
Angiotensin blocks substance P release from renal sensory nerves by inhibiting PGE2-mediated activation of cAMP	23
Circadian variation in the release of small extracellular vesicles can be normalized by vesicle number or TSG101	23
Altered V-ATPase expression in renal intercalated cells isolated from B1 subunit-deficient mice by fluorescence-activated cell sorting	23
Identification of novel metabolomic biomarkers in an experimental model of septic acute kidney injury	23
Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis	23
Molecular and functional characterization of a urea transporter from the kidney of the Atlantic stingray	23
Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury	23
Suramin protects from cisplatin-induced acute kidney injury	22
Alterations in cell-adhesive and migratory properties of proximal tubule and collecting duct cells from bcl-2 −/− mice	22
The protective effect of klotho against contrast-associated acute kidney injury via the antioxidative effect	22
Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids	22
Early podocyte injury and elevated levels of urinary podocyte-derived extracellular vesicles in swine with metabolic syndrome: role of podocyte mitochondria	22
PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death	22
Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion	22
Enhanced ammonia secretion by proximal tubules from mice receiving NH4Cl: role of angiotensin II	21
Reduced endothelial nitric oxide synthase activation contributes to cardiovascular injury during chronic kidney disease progression	21
Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-γ-miR-23 axis	21
Direct and indirect inhibition of the circadian clock protein Per1: effects on ENaC and blood pressure	21
Anion exchanger 1 in human kidney and oncocytoma differs from erythroid AE1 in its NH2 terminus	21
Glucocorticoid receptor activation stimulates the sodium-chloride cotransporter and influences the diurnal rhythm of its phosphorylation	21
Characterizing novel olfactory receptors expressed in the murine renal cortex	21
Recent advances in sex differences in kidney function	21
Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers	21
Ammonia production and secretion by S3 proximal tubule segments from acidotic mice: role of ANG II	21
Renal tubular effects of prolonged therapy with the GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes mellitus	21
TGF-β1 modifies histone acetylation and acetyl-coenzyme A metabolism in renal myofibroblasts	21
A zebrafish model of infection-associated acute kidney injury	21