American Journal of Physiology-Renal Physiology

Papers
(The TQCC of American Journal of Physiology-Renal Physiology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male Sprague-Dawley rats57
Role of the CDKL1-SOX11 signaling axis in acute kidney injury53
Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation52
Interleukin-6 blockade reduces salt-induced cardiac inflammation and fibrosis in subtotal nephrectomized mice35
Expression of leptin receptor in renal tubules is sparse but implicated in leptin-dependent kidney gene expression and function35
“Idiopathic” minimal change nephrotic syndrome: a podocyte mystery nears the end34
First Author Highlights33
Corrigendum for Jang et al., volume 326, 2024, p. F6932
First Author Highlights31
A mathematical model of the rat kidney. IV. Whole kidney response to hyperkalemia30
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism29
Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats29
Rapid development of vasopressin resistance in dietary K+ deficiency28
Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth28
Perinatal asphyxia leads to acute kidney damage and increased renal susceptibility in adulthood28
Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species27
First Author Spotlight25
First Author Highlights25
Circulating extracellular vesicles of patients with steroid-sensitive nephrotic syndrome have higher RAC1 and induce recapitulation of nephrotic syndrome phenotype in podocytes25
C-terminal fragment of fibroblast growth factor 23 improves heart function in murine models of high intact fibroblast growth factor 2325
Redox regulation in diabetic kidney disease24
Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression24
Activation of branched chain amino acid catabolism protects against nephrotoxic acute kidney injury23
Pax inhibition: stressing proximal tubule for successful repair23
A brief history of the cortical thick ascending limb: a systems-biology perspective22
Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury22
Porcine models of acute kidney injury21
Methylseq, single-nuclei RNAseq, and discovery proteomics identify pathways associated with nephron-deficit CKD in the HSRA rat model21
A combination of β-hydroxybutyrate and citrate ameliorates disease progression in a rat model of polycystic kidney disease21
Splenocyte transfer from hypertensive donors eliminates premenopausal female protection from ANG II-induced hypertension21
Metformin ameliorates bladder dysfunction in a rat model of partial bladder outlet obstruction20
Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease20
Mapping kidney tubule diameter ex vivo by diffusion MRI20
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease20
Polygenic genetic variation affecting antibody formation underlies hypertensive renal injury in the stroke-prone spontaneously hypertensive rat19
Renal cell markers: lighthouses for managing renal diseases19
Characterization of a functional V1B vasopressin receptor in the male rat kidney: evidence for cross talk between V1B and V2 receptor signaling pathways19
β2-Adrenergic receptor agonists: a new treatment for diabetic kidney disease?19
Hints for a kidney lactate shuttle and lactomone19
Defining protein expression in the kidney at large scale: from antibody validation to cytometry analysis19
Perspective on G protein-coupled receptors in renal physiology19
First Author Highlights18
Hyperphosphatemia and zinc deficiency in chronic kidney disease: unpacking their interconnected roles and nutritional implications18
Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase18
Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing18
Kidney hemodynamic function in men and postmenopausal women with type 2 diabetes and preserved kidney function18
Prolonged unilateral renal ischemia-reperfusion as a model for acute to chronic kidney injury in female mice18
Long-term follow-up of TREK-1 KO mice reveals the development of bladder hypertrophy and impaired bladder smooth muscle contractility with age18
SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy18
Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy18
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury18
Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats18
Overview of acute kidney manifestations and management of patients with COVID-1917
Cilia-deficient renal tubule cells are primed for injury with mitochondrial defects and aberrant tryptophan metabolism17
Angiotensin in the acute and chronic responses to unilateral nephrectomy17
Angiotensin type 2 receptor activation limits kidney injury during the early phase and induces Treg cells during the late phase of renal ischemia17
Dysregulation of the sensory and regulatory pathways controlling cellular iron metabolism in unilateral obstructive nephropathy17
15-Lipoxygenase worsens renal fibrosis, inflammation, and metabolism in a murine model of ureteral obstruction17
Ubiquitination of NKCC2 by the cullin-RING E3 ubiquitin ligase family in the thick ascending limb of the loop of Henle16
First Author Spotlight16
Novel insight on physiological regulation of the Cl/HCO3− exchanger pendrin16
Delayed graft function post renal transplantation: a review on animal models and therapeutics16
Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction16
Corrigendum for Fu et al., volume 317, 2019, p. F1582–F159215
Macrophage angiotensin AT2 receptor activation is protective against early phases of LPS-induced acute kidney injury15
Investigating FSGS-like injury in zebrafish larvae by nifurpirinol: efficacy and molecular insight15
Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron15
Influence of proteolytic cleavage of ENaC’s γ subunit upon Na+ and K+ handling15
Metformin reduces insulin resistance and attenuates progressive renal injury in prepubertal obese Dahl salt-sensitive rats15
Commensal microbiota regulate aldosterone15
Characterization of FAM114A1: a novel podocyte cytoskeleton-associated protein upregulated in glomerular injury14
Recent advances in understanding the kidney circadian clock mechanism14
High baseline ROMK activity in the mouse late distal convoluted and early connecting tubule probably contributes to aldosterone-independent K+ secretion14
High dietary K+ intake inhibits proximal tubule transport14
Impaired nitric oxide mechanisms underlying lower urinary tract dysfunction in aging rats14
Psychotropic drugs upregulate aquaporin-2 via vasopressin-2 receptor/cAMP/protein kinase A signaling in inner medullary collecting duct cells13
Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease13
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice13
Predicting oxygen tension along the ureter13
First Author Spotlight13
Angiotensin II-stimulated proximal nephron superoxide production and fructose-induced salt-sensitive hypertension12
The kidney in health and disease in 2022: Gaps in and opportunities for new knowledge12
Mapping single-nephron filtration in the isolated, perfused rat kidney using magnetic resonance imaging12
First Author Spotlight12
TNIK depletion induces inflammation and apoptosis in injured renal proximal tubule epithelial cells12
Proximal tubule cyclophilin D mediates kidney fibrogenesis in obstructive nephropathy12
Inducible deletion of the prostaglandin EP3 receptor in kidney tubules of male and female mice has no major effect on water homeostasis11
Pendrin regulation is prioritized by anion in high-potassium diets11
Kir4.1/Kir5.1 of distal convoluted tubule is required for short-term angiotensin-II-induced stimulation of Na-Cl cotransporter11
Amiloride lowers plasma TNF and interleukin-6 but not interleukin-17A in patients with hypertension and type 2 diabetes11
Sex-disaggregated analysis of acute kidney injury in hospitalized children with sickle cell anemia in Uganda11
Exogenous pericyte delivery protects the mouse kidney from chronic ischemic injury11
Sex differences in dietary sodium evoked NCC regulation and blood pressure in male and female Sprague-Dawley, Dahl salt-resistant, and Dahl salt-sensitive rats11
The impact of maternal obesity on polycystic kidney disease progression in a mouse model11
A novel functional role for the classic CNS neurotransmitters, GABA, glycine, and glutamate, in the kidney: potent and opposing regulators of the renal vasculature11
A brief harvesting-freezing delay significantly alters the kidney metabolome and leads to false positive and negative results11
Revisiting voltage-coupled H+ secretion in the collecting duct11
Downloadable Tool for Modeling of Salt, Urea and Water Transport in a Renal Tubule Segment: Application to the DCT11
Impaired hemodynamic renal reserve response following recovery from established acute kidney injury and improvement by hydrodynamic isotonic fluid delivery11
Physiology assays in human kidney organoids11
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment11
Regulation of kidney mitochondrial function by caloric restriction11
Chronic kidney disease amplifies severe kidney injury and mortality in a mouse model of skin arsenical exposure10
Furin-Mediated Modification Is Required for Epithelial Sodium Channel-Activating Activity of Soluble (Pro)Renin Receptor in Cultured Collecting Duct Cells10
Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients10
Prevention of hypertension-induced renal vascular dysfunction through a p66Shc-targeted mechanism10
Renal claudin-14 expression is not required for regulating Mg2+ balance in mice10
Male Akita mice develop signs of bladder underactivity independent of NLRP3 as a result of a decrease in neurotransmitter release from efferent neurons10
Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis10
Insulin-regulated aminopeptidase is required for water excretion in response to acute hypotonic stress10
Injury in nonaged podocytes as an accelerator of glomerular aging10
JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice10
Bayesian mapping of protein kinases to vasopressin-regulated phosphorylation sites in renal collecting duct10
First Author Highlights10
Antibiotic-induced microbiome depletion alters renal glucose metabolism and exacerbates renal injury after ischemia-reperfusion injury in mice10
Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation: implications for glomerular hemodynamics10
CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes10
Practical notes on popular statistical tests in renal physiology10
Parental obesity predisposes offspring to kidney dysfunction and increased susceptibility to ischemia-reperfusion injury in a sex-dependent manner10
HMGB1 drives T-cell activation in hypertensive males and females10
Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury10
Collectrin (Tmem27) deficiency in proximal tubules causes hypertension in mice and a TMEM27 variant associates with blood pressure in males in a Latino cohort10
Effects of SGLT2 inhibitor and dietary NaCl on glomerular hemodynamics assessed by micropuncture in diabetic rats9
Image analysis techniques to map pyramids, pyramid structure, glomerular distribution, and pathology in the intact human kidney from 3-D MRI9
First Author Highlights9
Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity9
Flow-dependent transport processes 2024: filtration, absorption, secretion9
Nicotinamide ameliorates podocyte injury and albuminuria in adriamycin-induced nephropathy9
β2-Adrenergic receptor agonists as a treatment for diabetic kidney disease9
Novel method for kinetic analysis applied to transport by the uniporter OCT29
HIF-1α is transcriptionally regulated by NF-κB in acute kidney injury9
The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in the human kidney9
A stressed barrier left behind: stochastic podocyte ablation triggers secondary injury9
Macrophage SPAK deletion limits a low potassium-induced kidney inflammatory program9
IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage9
Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury9
Creatinine clearance is maintained in a range of wet-bulb globe temperatures and work-rest ratios during simulated occupational heat stress9
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury9
Promises and challenges of miRNA therapeutics9
Mitochondrial dysfunction in the pathophysiology of renal diseases9
Mechanisms of decreased tubular flow-induced nitric oxide in Dahl salt-sensitive rat thick ascending limbs9
The Indiana O’Brien Center for Advanced Renal Microscopic Analysis9
The miR-143/145 cluster induced by TGF-β1 suppresses Wilms’ tumor 1 expression in cultured human podocytes9
Postoperative acute kidney injury after volatile or intravenous anesthesia: a meta-analysis9
Transcription factor HNF1β controls a transcriptional network regulating kidney cell structure and tight junction integrity9
Pathways and parameters of sacral neuromodulation in rats8
Endothelin-1 signaling in the kidney: recent advances and remaining gaps8
Kidney functional reserve helps early detection of subclinical chronic kidney disease8
Role of protease-activated receptor 4 in mouse models of acute and chronic kidney injury8
IFT88 deficiency in proximal tubular cells exaggerates cisplatin-induced injury by suppressing autophagy8
Longitudinal intravital microscopy of the mouse kidney: inflammatory responses to abdominal imaging windows8
Indirect podocyte injury manifested in a partial podocytectomy mouse model8
Assays to enhance metabolic phenotyping in the kidney8
Vascular control of kidney epithelial transporters8
Machine-perfused donor kidneys as a source of human renal endothelial cells8
First Author Spotlight8
Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease8
The degree of aortic occlusion in the setting of trauma alters the extent of acute kidney injury associated with mitochondrial preservation8
Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation8
First Author Highlights8
Tacrolimus induces fibroblast-to-myofibroblast transition via a TGF-β-dependent mechanism to contribute to renal fibrosis8
Fasting-induced HMGCS2 expression in the kidney does not contribute to circulating ketones8
Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance8
Predicting sex differences in the effects of diuretics in renal epithelial transport during angiotensin II-induced hypertension8
Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice8
High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults8
A mathematical model of the rat kidney. III. Ammonia transport8
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