OOIR: Observatory of International Research

Papers

(The TQCC of IUBMB Life is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Issue Information	76
Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	73
Issue Information	70
Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	58
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	47
SHP2: The protein tyrosine phosphatase involved in chronic pulmonary inflammation and fibrosis	43
LEAP‐2/ghrelin interplay in adult growth hormone deficiency: Cause or consequence? A pilot study	40
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	38
Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	37
Mitochondrial protein and organelle quality control—Lessons from budding yeast	36
Serum/glucocorticoid‐regulated kinase 1‐targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activat	35
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	34
The roles of proteases in prostate cancer	32
Gastrointestinal tissue as a “new” target of pollution exposure	30
Issue Information	29
The role of the proteasome in mitochondrial protein quality control	29
Central nervous system cholesterol metabolism in health and disease	28
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	27
	27
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	25
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	24
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	24
miR‐126 regulates the proliferation, migration, invasion, and apoptosis of non‐small lung cancer cells via AKT2/HK2 axis	23
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	23
Arabidopsis thaliana possesses two novel ELL associated factor homologs	23

Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	22
Optimization of the chromium (Cr⁺⁶) reduction from waterways using chemically and bacterially treated agro‐waste	21
RETRACTION: Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	21
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	21
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	20
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	20
N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	19
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	19
Cholesterol‐dependent cytolysins: The outstanding questions	19
Underlying selection for the diversity of spike protein sequences of SARS‐CoV‐2	17
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	17
Issue Information	17
FOXO transcription factors in antioxidant defense	17
	16
Issue Highlights	16
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	15
Central nervous system organoids for modeling neurodegenerative diseases	15
Dynamic association of flavin cofactors to regulate flavoprotein function	15
Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	14
Knockdown of ST6Gal‐I expression in human hepatocellular carcinoma cells inhibits their exosome‐mediated proliferation‐ and migration‐promoting effects	14
Issue Information	14
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	14
Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	14
One‐year mortality and consequences of COVID‐19 in cancer patients: A cohort study	14
Eddy Fischer—Renaissance scientist and bon viveur	14
Issue Information	14
Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	13
Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV‐2 targeting main protease and papain‐like protease	13
2‐Deoxy‐d‐glucose exploits increased glucose metabolism in cancer and viral‐infected cells: Relevance to its use in India against SARS‐CoV‐2	13
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	13
Urinary proteomic analysis to identify a potential protein biomarker panel for the diagnosis of tuberculosis	12
Issue Highlights	12
Issue Information	12
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	12
Role of extracellular vesicles in mitochondrial eye diseases	11
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	11
	11
Issue Highlights	11
Erythroid spectrin binding modulates peroxidase and catalase activity of heme proteins	11
Cover Image	11
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	11
The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	11
Issue Information	11
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	11
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	11
Issue Information	11
Issue Information	11
RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	10
Pseudoexfoliation syndrome: The critical role of the extracellular matrix in pathogenesis and treatment	10
Endoplasmic reticulum stress and NF‐kB activation in SARS‐CoV‐2 infected cells and their response to antiviral therapy	10

Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	10
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	10
RetroGREAT signaling: The lessons we learn from yeast	9
Genomic features of lichen‐associated black fungi	9
	9
Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	9
Corrigendum	9
	9
Variability in the levels of exosomal miRNAs among human subjects could be explained by differential interactions of exosomes with the endothelium	8
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
EXPRESSION OF CONCERN: Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	8
Cover Image	8
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	8
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	8
Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8
Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
Placenta‐specific protein 1 promotes cell proliferation via the AKT/GSK‐3β/cyclin D1 signaling pathway in gastric cancer	7
	7
Comparative analysis of the potential of the secretomes of cardiac resident stromal cells and fibroblasts	7
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	7
N1‐methyladenosine profiling of long non‐coding RNA in colorectal cancer	7
A standardised nomenclature for long non‐coding RNAs	7
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	7
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	7
Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
miR‐543 in human mesenchymal stem cell–derived exosomes promotes cardiac microvascular endothelial cell angiogenesis after myocardial infarction through COL4A1	7
	7
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	6
A decoy strategy to activate the immune system	6
Regulation of innate immune signaling pathways by autophagy in dengue virus infection	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
Issue Information	6
The ins and outs of the flavin mononucleotide cofactor of respiratory complex I	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
Issue Highlights	6
Golgi quality control and autophagy	6
Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	6
Cover Image	6
	6
The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	6
Mechanisms of adaptive hypertrophic cardiac remodeling in a large animal model of premature ventricular contraction‐induced cardiomyopathy	5
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β‐catenin signaling pathway in human breast cancer cells	5
Correction to “LncRNA RAD51‐AS1/miR‐29b/c‐3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer”	5
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	5
1,25(OH)₂D₃ inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	5
CPEB1 enhances erastin‐induced ferroptosis in gastric cancer cells by suppressing twist1 expression	5
The redox signal: A physiological perspective	5
Issue Information	5
Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation	5
Corrigendum	5
The multifaceted antineoplastic role of pyrimethamine against human malignancies	5
Cover Image	5
Erratum	5
Issue Information	5
Issue Information	5
	5
Correction to “Retraction”	5
Issue Information	5
Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis	5
N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
Nano‐therapeutics: The upcoming nanomedicine to treat cancer	5
Issue Highlights	5