OOIR: Observatory of International Research

Papers

(The TQCC of IUBMB Life is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Issue Information	100
Issue Information	53
	52
Discovery and Validation of a New Biomarker Integrating Ferroptosis and Glycolysis‐Related Genes in Bladder Cancer	45
Mitochondrial protein and organelle quality control—Lessons from budding yeast	44
Modulation of PPAR‐α and PPAR‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling	40
Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	39
Issue Information	30
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	27
Serum/glucocorticoid‐regulated kinase 1‐targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activat	27
Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	26
Issue Information	25
Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	25
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	24
The role of the proteasome in mitochondrial protein quality control	24
Next‐Generation Nanomaterials in Biology: From Tissue Regeneration to Targeted Cancer Therapy	22
Central nervous system cholesterol metabolism in health and disease	22
The roles of proteases in prostate cancer	22
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	21
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	21
RETRACTION: Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	20
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	20
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	19
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	19
Optimization of the chromium (Cr⁺⁶) reduction from waterways using chemically and bacterially treated agro‐waste	19

N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	19
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	18
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	18
Cholesterol‐dependent cytolysins: The outstanding questions	17
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	17
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	17
Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	17
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	16
Central nervous system organoids for modeling neurodegenerative diseases	15
Eddy Fischer—Renaissance scientist and bon viveur	15
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Issue Information	15
Issue Highlights	15
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	15
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	15
Issue Information	15
Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	14
Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	14
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	14
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	13
Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	13
Dynamic association of flavin cofactors to regulate flavoprotein function	13
Euryhaline Black Yeasts From the Arabian Gulf: Descriptions of Salinomyces qatarensis sp. nov. and Hortaea werneckii Genotypic Variations	12
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	12
Issue Information	12
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	12
Issue Information	12
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	11
Cover Image	11
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	11
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	11
Correction to “Tissue Factor Driven Coagulation and Inflammation in Lung Injury: Insights From In Vitro and In Vivo Models”	10
Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV ‐2 targeting main protease and papain‐like protease	10
Role of extracellular vesicles in mitochondrial eye diseases	10
Issue Information	10
Issue Information	9
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	9
Issue Highlights	9
17‐Oxo‐DHA Potentiates Macrophage Efferocytosis via Nrf2/HO‐1‐Mediated Biosynthesis of Specialized Pro‐Resolving Mediators	9
RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	9
Erythroid spectrin binding modulates peroxidase and catalase activity of heme proteins	9
Correction to “Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3”	9
Pseudoexfoliation syndrome: The critical role of the extracellular matrix in pathogenesis and treatment	9
The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	9
Issue Information	9
	8
RetroGREAT signaling: The lessons we learn from yeast	8
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	8
MIA3 in Coronary Artery Disease ( CAD ): An In‐Depth Review of Its	8

Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	8
Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	8
EXPRESSION OF CONCERN: Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	8
Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	8
Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8
	8
Integrated Analysis of Single‐Cell and Bulk RNA Sequencing Data Reveals Cellular Senescence‐Related Signatures Predicting New Potential Therapeutic Drugs in Hepatic Ischemia‐Reperfusion Inj	8
Genomic features of lichen‐associated black fungi	8
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	7
The ins and outs of the flavin mononucleotide cofactor of respiratory complex I	7
	7
Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
Cover Image	7
A standardised nomenclature for long non‐coding RNAs	7
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	7
	7
All‐Trans Retinoic Acid as a Predictor and Therapeutic Agent for Vascular Calcification	7
Gastric Cancer Cell‐Derived Exosomes Induce Macrophage M2 Polarization by Delivering circSMARCC1 t	6
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	6
Issue Information	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	6
1,25(OH)₂D₃ inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	6
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	6
Analysis of miRNA Expression Profiles in High Cholesterol Diet‐Induced MASH Progression: Potential Effect of α‐Tocopherol	6
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase‐3 and NFκB Signaling	6
Nano‐therapeutics: The upcoming nanomedicine to treat cancer	6
The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
Cover Image	6
Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation	6
Golgi quality control and autophagy	6
Cover Image	5
Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes	5
	5
Issue Information	5
Issue Information	5
N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
Issue Information	5
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β‐catenin signaling pathway in human breast cancer cells	5
Correction to “LncRNA RAD51‐AS1/miR‐29b/c‐3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer”	5
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	5
The multifaceted antineoplastic role of pyrimethamine against human malignancies	5
Issue Information	5
Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation	5
Correction to “Retraction”	5