IUBMB Life

Article	Citations
Issue Information	96
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Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	44
Discovery and Validation of a New Biomarker Integrating Ferroptosis and Glycolysis‐Related Genes in Bladder Cancer	43
Mitochondrial protein and organelle quality control—Lessons from budding yeast	40
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	33
The roles of proteases in prostate cancer	30
Modulation of PPAR‐α and PPAR‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling	27
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	27
Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	25
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	24
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Serum/glucocorticoid‐regulated kinase 1‐targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activat	23
Central nervous system cholesterol metabolism in health and disease	22
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Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	22
The role of the proteasome in mitochondrial protein quality control	21
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	20
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	19
Optimization of the chromium (Cr+6) reduction from waterways using chemically and bacterially treated agro‐waste	19
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	19
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	19
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	19
N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	19

RETRACTION: Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	19
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	18
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	17
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	17
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	16
Underlying selection for the diversity of spike protein sequences of SARS‐CoV‐2	16
Issue Highlights	15
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	15
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Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	15
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Cholesterol‐dependent cytolysins: The outstanding questions	15
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Eddy Fischer—Renaissance scientist and bon viveur	14
Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	14
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	14
Central nervous system organoids for modeling neurodegenerative diseases	14
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	13
Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	12
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	12
Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	12
Dynamic association of flavin cofactors to regulate flavoprotein function	12
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	11
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	11
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Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	11
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	11
Euryhaline Black Yeasts From the Arabian Gulf: Descriptions of Salinomyces qatarensis sp. nov. and Hortaea werneckii Genotypic Variations	11
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Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV‐2 targeting main protease and papain‐like protease	10
Role of extracellular vesicles in mitochondrial eye diseases	10
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	9
Correction to “Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3”	9
Erythroid spectrin binding modulates peroxidase and catalase activity of heme proteins	9
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RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	9
Pseudoexfoliation syndrome: The critical role of the extracellular matrix in pathogenesis and treatment	9
Correction to “Tissue Factor Driven Coagulation and Inflammation in Lung Injury: Insights From In Vitro and In Vivo Models”	9
Issue Highlights	9
17‐Oxo‐DHA Potentiates Macrophage Efferocytosis via Nrf2/HO‐1‐Mediated Biosynthesis of Specialized Pro‐Resolving Mediators	9
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The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	8
Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	8
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Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	8
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Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	8
Genomic features of lichen‐associated black fungi	8

Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
Integrated Analysis of Single‐Cell and Bulk RNA Sequencing Data Reveals Cellular Senescence‐Related Signatures Predicting New Potential Therapeutic Drugs in Hepatic Ischemia‐Reperfusion Inj	8
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	8
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	8
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Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
RetroGREAT signaling: The lessons we learn from yeast	8
A standardised nomenclature for long non‐coding RNAs	8
EXPRESSION OF CONCERN: Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	7
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All‐Trans Retinoic Acid as a Predictor and Therapeutic Agent for Vascular Calcification	7
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Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
Variability in the levels of exosomal miRNAs among human subjects could be explained by differential interactions of exosomes with the endothelium	7
Gastric Cancer Cell‐Derived Exosomes Induce Macrophage M2 Polarization by Delivering circSMARCC1 t	7
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Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	7
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	7
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	6
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	6
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1,25(OH)2D3 inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
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Analysis of miRNA Expression Profiles in High Cholesterol Diet‐Induced MASH Progression: Potential Effect of α‐Tocopherol	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
Nano‐therapeutics: The upcoming nanomedicine to treat cancer	6
Golgi quality control and autophagy	6
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	6
The ins and outs of the flavin mononucleotide cofactor of respiratory complex I	6
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase‐3 and NFκB Signaling	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	5
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Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis	5
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N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
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The multifaceted antineoplastic role of pyrimethamine against human malignancies	5
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The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	5
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	5
The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation	5
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Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes	5
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Delivery of AKT1 phospho‐forms to human cells reveals differential substrate selectivity	4
Correction to “LncRNA RAD51‐AS1/miR‐29b/c‐3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer”	4
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β‐catenin signaling pathway in human breast cancer cells	4
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Biolistic transformation of the yeast Saccharomyces cerevisiae mitochondrial DNA	4
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Correction to “Retraction”	4
Mechanisms of adaptive hypertrophic cardiac remodeling in a large animal model of premature ventricular contraction‐induced cardiomyopathy	4
Disrupted cellular calcium homeostasis is responsible for Aβ‐induced learning and memory damage and lifespan shortening in a model of Aβ transgenic fly	4
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Pyrimidine–triazole‐tethered tert‐butyl‐piperazine‐carboxylate suppresses breast cancer by targeting estrogen receptor signaling and β‐catenin activation	4
Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depleti	4
Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation	4
Corrigendum	4
Machine learning‐based establishment and validation of age‐related patterns for predicting prognosis in non‐small cell lung cancer within the context of the tumor microenvironment	4
Establishment of Initiated Cell Line Derived From NIH3T3 Fibroblasts	3
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The CD40/CD40 ligand dyad and its downstream effector molecule ISG54 in relating acute neuroinflammation with persistent, progressive demyelination	3
Cyclin‐dependent kinase 7 is essential for spermatogenesis by regulating retinoic acid signaling pathways and the STAT3 molecular pathway	3
Hypoxia inducible factor 3‐alpha promotes a malignant phenotype in colorectal cancer cells	3
Mammalian iron sulfur cluster biogenesis and human diseases	3
Advancing Therapeutic Strategies for Nonsense‐Related Diseases: From Small Molecules to Nucleic Acid‐Based Innovations	3
The IUBMB Focused Meeting on Aminoacyl‐tRNA Synthetases 2023	3
The long intergenic noncoding RNA ARES modulates root architecture in Arabidopsis	3
CircROBO2 Orchestrates Osimertinib Resistance Through miR‐625‐5p/PDGFB‐Mediated MAPK Activation in Non‐Small Cell Lung Cancer	3
Melatonin effect on breast and ovarian cancers by targeting the PI3K/Akt/mTOR pathway	3
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Amyloid‐β40 E22K fibril in familial Alzheimer's disease is more thermostable and susceptible to seeding	3
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Wnt signaling in cell adhesion, development, and colon cancer	3

RING Finger Protein 4 (RNF4) Reduces Nonalcoholic Fatty Liver Disease Accumulation by Promoting the SUMOylation of HIF‐2α and Regulating the PPARα	3
Deciphering the senescence‐based tumoral heterogeneity and characteristics in pancreatic cancer: Results from parallel bulk and single‐cell transcriptome data	3
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p62 bodies: Phase separation, NRF2 activation, and selective autophagic degradation	3
Humanized disulfide‐stabilized diabody against fibroblast growth factor‐2 inhibits PD‐L1 expression and epithelial‐mesenchymal transition in hepatoma cells through STAT3	2
MYC‐Mediated Osseous Regeneration via BMSCs/PRP/β‐TCP/PCL Bioprinted Constructs: Rapid Defect Rehabilitation and Preliminary Clinical Efficacy Ev	2
MRASin coronary artery disease—Unchartered territory	2
Novel NRF2‐activated cancer treatments utilizing synthetic lethality	2
Brucein D imparts a growth inhibitory effect in multiple myeloma cells by abrogating the Akt‐driven signaling pathway	2
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Pan‐Cancer Analysis Identifies DIP2B as a Potential Biomarker That Inhibits Kidney Renal Clear Cell Carcinoma Progression	2
Redefining pseudokinases: A look at the untapped enzymatic potential of pseudokinases	2
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Zinc finger protein 169 promotes tumor progress of hepatocellular cancer via up‐regulating cyclin‐dependent kinase 19	2
Enhancing the activation of T cells through anti‐CD3/CD28 magnetic beads by adjusting the antibody ratio	2
Single‐Cell Profiling of the Microenvironment in High‐Risk Neuroblastoma	2
Involvement of sialoglycans in SARS‐COV‐2 infection: Opportunities and challenges for glyco‐based inhibitors	2
Reflections on the 50‐year history of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)	2
Cholesteryl ester transfer protein knock‐down in conjunction with a cholesterol‐depleting agent decreases tamoxifen resistance in breast cancer cells	2
Aminoacyl‐tRNA synthetase defects in neurological diseases	2
miRNAs are now starring in “No Time to Die: Overcoming the chemoresistance in cancer”	2
Investigation through naphtho[2,3‐a]pyrene on mutated EGFR mediated autophagy in NSCLC: Cellular model system unleashing therapeutic potential	2
Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction	2
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Retraction: miR‐212/132 downregulates SMAD2 expression to suppress the G1/S phase transition of the cell cycle and the epithelial to mesenchymal transition in cervical	2
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Contrast‐Induced Acute Kidney Injury is Modulated by Circadian CLOCK/NRF2 Pathway	2
Machine learning applications for transcription level and phenotype predictions	2
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Blood Coagulation Factor IX: Structure, Function, and Regulation	2
Hederagenol improves multiple sclerosis by modulating Th17 cell differentiation	2
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Rapamycin treatment unmasks a sex‐specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel	2
miRNA‐128 and miRNA‐223 regulate cholesterol‐mediated drug resistance in breast cancer	2
KLHL38 facilitates staurosporine‐induced apoptosis in HL‐1 cells via myocardin degradation	2
Neonatal exposure to low‐dose X‐ray causes behavioral defects and abnormal hippocampal development in mice	2
The combination of midkine inhibitor with Lenvatinib amplifies the suppression of hepatocellular carcinoma	2
Identification, subcellular localization, and functional comparison of novel Yap splicing isoforms in mouse embryonic stem cells	2
MiR‐3680‐3p is a novel biomarker for the diagnosis and prognosis of liver cancer and is involved in regulating the progression of liver cancer	2
Bioinformatics‐Based Exploration of LMO4‐Regulated Hippo Pathway to Reverse Adriamycin Resistance in Breast Cancer	1
The therapeutic effects of induced pluripotent stem cell‐derived mesenchymal stem cells on Parkinson's disease	1
HucMSC extracellular vesicles increasing SATB 1 to activate the Wnt/β‐catenin pathway in 6‐OHDA‐induced Parkinson's disease model	1
Long‐term abuse of caffeine sodium benzoate induces endothelial cells injury and leads to coagulation dysfunction	1
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LncRNA RP11‐301G19.1 is required for the maintenance of vascular smooth muscle cell contractile phenotype via sponging miR‐17‐5P/ATOH8 axis	1
Characterization of O‐mannosylated proteins profiling in bacillus Calmette–Guérin via gel‐based and gel‐free approaches	1
β‐Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts	1
The latest achievements in biochemistry, biophysics and biotechnology—50 years of history of the Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Poland	1
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Structural aspects of the glucose and monocarboxylate transporters involved in the Warburg effect	1
Genetic tools to dissect functions of long noncoding RNAs	1
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A high‐throughput approach to predict A‐to‐I effects on RNA structure indicates a change of double‐stranded content in noncoding RNAs	1
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE‐3 cells by upregulating ERRFI1	1
Microtubule depolymerization induces ferroptosis in neuroblastoma cells	1
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CDCA4 / SERTAD1 / E2F1 Facilitates Lung Adenocarcinoma Progression	1
The scientific career and life of Edmond H. Fischer—A personal tribute	1
Erratum to Associations between the polymorphisms of main components in PI3K/Akt pathway and risk of diabetic kidney disease: A meta‐analysis	1
Histone demethylase LSD1 promotes castration‐resistant prostate cancer by causing widespread gene expression derangements	1
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Screening and experimental validation of diagnostic gene in ulcerative colitis with anti‐TNF‐α therapy	1
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Coexisting bacterial aminoacyl‐tRNAsynthetase paralogs exhibit distinct phylogenetic backgrounds and functional compatibility withEscherichia coli	1
Fingolimod (FTY720), an FDA‐approved sphingosine 1‐phosphate (S1P) receptor agonist, restores endothelial hyperpermeability in cellular and animal models of dengue vir	1
CDKN3 as a key regulator of G2M phase in triple‐negative breast cancer: Insights from multi‐transcriptomic analysis	1
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DYRK1A Overexpression Drives Muscle Wasting by Impeding Myogenesis via a USP7‐Axin1‐β‐Catenin Regulatory Axis in Mice	1
A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer	1
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Differential expression of HNF1A and HNF1A‐AS1 in colon cancer cells	1
Genetic variations in NER pathway gene polymorphisms and Wilms tumor risk: A six‐center case–control study in East China	1
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MyomiRs Expression in Limb Girdle Muscular Dystrophy	1
Nuclear and cytoplasmic lncRNAs in root tips of the model legume Medicago truncatula under control and submergence	1
Underlining the Molecular Mechanism of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in Lipid Metabolism by Combining Multiple Sets of Data Sets	1
A hub for regulation of mitochondrial metabolism: Fatty acid and lipoic acid biosynthesis	1
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Phosphorylation, compartmentalization, and cardiac function	1
LncRTPred: Predicting RNA–RNA mode of interaction mediated by lncRNA	1
Correction to “The latest achievements in biochemistry, biophysics and biotechnology—50 years of history of the Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków	1
Functional TET2 gene polymorphisms increase the risk of neuroblastoma in Chinese children	1
Biosynthesis of uridine diphosphate N‐Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?	1
Nuclear Aggregates of Polyamines– DNA Complexes Imply a Genomic Electronic Circuit	1
Synergistic integration of deep learning with protein docking in cardiovascular disease treatment strategies	1