IUBMB Life

Article	Citations
Issue Information	117
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Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	62
Discovery and Validation of a New Biomarker Integrating Ferroptosis and Glycolysis‐Related Genes in Bladder Cancer	57
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Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	34
Central nervous system cholesterol metabolism in health and disease	33
Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	32
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	29
Mitochondrial protein and organelle quality control—Lessons from budding yeast	29
Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	28
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The roles of proteases in prostate cancer	26
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Next‐Generation Nanomaterials in Biology: From Tissue Regeneration to Targeted Cancer Therapy	24
Modulation of PPAR‐α and PPAR‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling	24
The role of the proteasome in mitochondrial protein quality control	23
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	22
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	22
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	21
Optimization of the chromium (Cr+6) reduction from waterways using chemically and bacterially treated agro‐waste	21
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	20
Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	20
Cholesterol‐dependent cytolysins: The outstanding questions	18
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	18

N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	17
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	17
RETRACTION : Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	17
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	16
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	16
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	15
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	14
Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	13
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	13
Eddy Fischer—Renaissance scientist and bon viveur	13
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Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	13
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	13
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Hypoxia‐Inducible Factors as Guardians of Cancer Stem Cell Fate: Implications for Novel Therapies	12
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Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	12
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	12
Euryhaline Black Yeasts From the Arabian Gulf: Descriptions of Salinomyces qatarensis sp. nov. and Hortaea werneckii Genotypic Variations	12
Deciphering the Angiogenic Switch: The Role of miRNAs in Breast Cancer	12
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	12
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Correction to “Tissue Factor Driven Coagulation and Inflammation in Lung Injury: Insights From In Vitro and In Vivo Models”	10
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	10
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	10
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	10
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	10
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	10
Role of extracellular vesicles in mitochondrial eye diseases	10
Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV ‐2 targeting main protease and papain‐like protease	10
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The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	9
RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	9
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Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	9
Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	9
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Correction to “Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3”	9
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	9
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MIA3 in Coronary Artery Disease ( CAD ): An In‐Depth Review of Its	9
17‐Oxo‐DHA Potentiates Macrophage Efferocytosis via Nrf2/HO‐1‐Mediated Biosynthesis of Specialized Pro‐Resolving Mediators	9
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
RetroGREAT signaling: The lessons we learn from yeast	8
Genomic features of lichen‐associated black fungi	8

Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8
Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
CYP17A1 Locus: Regulatory Mechanisms and Clinical Associations With Cardiovascular Disease and Metabolic Syndrome	8
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Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	7
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A standardised nomenclature for long non‐coding RNAs	7
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Gastric Cancer Cell‐Derived Exosomes Induce Macrophage M2 Polarization by Delivering circSMARCC1 t	7
All‐Trans Retinoic Acid as a Predictor and Therapeutic Agent for Vascular Calcification	7
Integrated Analysis of Single‐Cell and Bulk RNA Sequencing Data Reveals Cellular Senescence‐Related Signatures Predicting New Potential Therapeutic Drugs in Hepatic Ischemia‐Reperfusion Inj	7
EXPRESSION OF CONCERN : Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	7
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	7
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	7
Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	7
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	6
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Nano‐therapeutics: The upcoming nanomedicine to treat cancer	6
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Analysis of miRNA Expression Profiles in High Cholesterol Diet‐Induced MASH Progression: Potential Effect of α‐Tocopherol	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	6
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	6
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase‐3 and NFκB Signaling	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	6
1,25(OH)2D3 inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	6
The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	5
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	5
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Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes	5
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N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
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ADAM15 Is a Potential Biomarker for Pan‐Cancer Prognosis and Immunotherapy: Validation in HCC and	5
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The long intergenic noncoding RNA ARES modulates root architecture in Arabidopsis	4
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Mechanisms of adaptive hypertrophic cardiac remodeling in a large animal model of premature ventricular contraction‐induced cardiomyopathy	4
Correction to “ LncRNA RAD51‐AS1 / miR ‐29b/c‐3p/ NDRG2	4
Correction to “Retraction”	4
Machine learning‐based establishment and validation of age‐related patterns for predicting prognosis in non‐small cell lung cancer within the context of the tumor microenvironment	4
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Biolistic transformation of the yeast Saccharomyces cerevisiae mitochondrial DNA	4
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Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depleti	4
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Disrupted cellular calcium homeostasis is responsible for Aβ‐induced learning and memory damage and lifespan shortening in a model of Aβ transgenic fly	4
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Pyrimidine–triazole‐tethered tert‐butyl‐piperazine‐carboxylate suppresses breast cancer by targeting estrogen receptor signaling and β‐catenin activation	4
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Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation	4
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β‐catenin signaling pathway in human breast cancer cells	4
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Delivery of AKT1 phospho‐forms to human cells reveals differential substrate selectivity	4
Wnt signaling in cell adhesion, development, and colon cancer	4
MTFR1 Promotes Proliferation and Metastasis of Triple‐Negative Breast Cancer by Regulating Mitochondrial Metabolism	3
Novel NRF2‐activated cancer treatments utilizing synthetic lethality	3
Cholesteryl ester transfer protein knock‐down in conjunction with a cholesterol‐depleting agent decreases tamoxifen resistance in breast cancer cells	3
MiR‐3680‐3p is a novel biomarker for the diagnosis and prognosis of liver cancer and is involved in regulating the progression of liver cancer	3
Hypoxia inducible factor 3‐alpha promotes a malignant phenotype in colorectal cancer cells	3
Blood Coagulation Factor IX: Structure, Function, and Regulation	3
Melatonin effect on breast and ovarian cancers by targeting the PI3K/Akt/mTOR pathway	3
RING Finger Protein 4 (RNF4) Reduces Nonalcoholic Fatty Liver Disease Accumulation by Promoting the SUMOylation of HIF‐2α and Regulating the PPARα	3
Establishment of Initiated Cell Line Derived From NIH3T3 Fibroblasts	3
p62 bodies: Phase separation, NRF2 activation, and selective autophagic degradation	3
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Machine learning applications for transcription level and phenotype predictions	3
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Future Prospects of Imatinib in Advanced Pulmonary Hypertension Management	3
Redefining pseudokinases: A look at the untapped enzymatic potential of pseudokinases	3
Humanized disulfide‐stabilized diabody against fibroblast growth factor‐2 inhibits PD‐L1 expression and epithelial‐mesenchymal transition in hepatoma cells through STAT3	3
MRASin coronary artery disease—Unchartered territory	3
CircROBO2 Orchestrates Osimertinib Resistance Through miR ‐625‐5p/ PDGFB	3
The CD40/CD40 ligand dyad and its downstream effector molecule ISG54 in relating acute neuroinflammation with persistent, progressive demyelination	3

The IUBMB Focused Meeting on Aminoacyl‐ tRNA Synthetases 2023	3
Hederagenol improves multiple sclerosis by modulating Th17 cell differentiation	3
MYC ‐Mediated Osseous Regeneration via BMSCs / PRP /β‐	3
Zinc finger protein 169 promotes tumor progress of hepatocellular cancer via up‐regulating cyclin‐dependent kinase 19	3
Neonatal exposure to low‐dose X‐ray causes behavioral defects and abnormal hippocampal development in mice	3
Aminoacyl‐tRNA synthetase defects in neurological diseases	3
Single‐Cell Profiling of the Microenvironment in High‐Risk Neuroblastoma	3
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Retraction: miR ‐212/132 downregulates SMAD2 expression to suppress the G	3
Reflections on the 50‐year history of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)	3
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Advancing Therapeutic Strategies for Nonsense‐Related Diseases: From Small Molecules to Nucleic Acid‐Based Innovations	3
Involvement of sialoglycans in SARS‐COV‐2 infection: Opportunities and challenges for glyco‐based inhibitors	3
Deciphering the senescence‐based tumoral heterogeneity and characteristics in pancreatic cancer: Results from parallel bulk and single‐cell transcriptome data	3
Enhancing the activation of T cells through anti‐CD3/CD28 magnetic beads by adjusting the antibody ratio	3
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Contrast‐Induced Acute Kidney Injury is Modulated by Circadian CLOCK/NRF2 Pathway	2
A high‐throughput approach to predict A‐to‐I effects on RNA structure indicates a change of double‐stranded content in noncoding RNAs	2
The combination of midkine inhibitor with Lenvatinib amplifies the suppression of hepatocellular carcinoma	2
Balancing Promise and Peril: Hemophilia Gene Therapy Insights	2
Brucein D imparts a growth inhibitory effect in multiple myeloma cells by abrogating the Akt‐driven signaling pathway	2
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Investigation through naphtho[2,3‐a]pyrene on mutated EGFR mediated autophagy in NSCLC: Cellular model system unleashing therapeutic potential	2
miRNAs are now starring in “No Time to Die: Overcoming the chemoresistance in cancer”	2
Pan‐Cancer Analysis Identifies DIP2B as a Potential Biomarker That Inhibits Kidney Renal Clear Cell Carcinoma Progression	2
Phosphorylation, compartmentalization, and cardiac function	2
DYRK1A Overexpression Drives Muscle Wasting by Impeding Myogenesis via a USP7‐Axin1‐β‐Catenin Regulatory Axis in Mice	2
CDCA4 / SERTAD1 / E2F1 Facilitates Lung Adenocarcinoma Progression	2
Punicalagin Targets FDX1 to Induce Cuproptosis for the Treatment of Gastric Cancer	2
Rapamycin treatment unmasks a sex‐specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel	2
Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction	2
Biosynthesis of uridine diphosphate N‐Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?	2
miRNA‐128 and miRNA‐223 regulate cholesterol‐mediated drug resistance in breast cancer	2
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE‐3 cells by upregulating ERRFI1	2
Nuclear Aggregates of Polyamines– DNA Complexes Imply a Genomic Electronic Circuit	2
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Correction to “The latest achievements in biochemistry, biophysics and biotechnology—50 years of history of the Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków	1
HucMSC extracellular vesicles increasing SATB 1 to activate the Wnt/β‐catenin pathway in 6‐OHDA‐induced Parkinson's disease model	1
Structural aspects of the glucose and monocarboxylate transporters involved in the Warburg effect	1
Nuclear and cytoplasmic lncRNAs in root tips of the model legume Medicago truncatula under control and submergence	1
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Underlining the Molecular Mechanism of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in Lipid Metabolism by Combining Multiple Sets of Data Sets	1
Multi‐Omics Analysis Reveals That the MAZ / HDGF Regulatory Axis Drives High‐Grade Serous Ovarian	1
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Screening and experimental validation of diagnostic gene in ulcerative colitis with anti‐TNF‐α therapy	1
Fingolimod (FTY720), an FDA‐approved sphingosine 1‐phosphate (S1P) receptor agonist, restores endothelial hyperpermeability in cellular and animal models of dengue vir	1
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LncRTPred: Predicting RNA–RNA mode of interaction mediated by lncRNA	1
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CDKN3 as a key regulator of G2M phase in triple‐negative breast cancer: Insights from multi‐transcriptomic analysis	1
Synergistic integration of deep learning with protein docking in cardiovascular disease treatment strategies	1
A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer	1
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The scientific career and life of Edmond H. Fischer—A personal tribute	1
Functional TET2 gene polymorphisms increase the risk of neuroblastoma in Chinese children	1
Genetic variations in NER pathway gene polymorphisms and Wilms tumor risk: A six‐center case–control study in East China	1
Erratum to Associations between the polymorphisms of main components in PI3K /Akt pathway and risk of diabetic kidney disease: A meta‐analysis	1
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Histone demethylase LSD1 promotes castration‐resistant prostate cancer by causing widespread gene expression derangements	1
LncRNA RP11‐301G19.1 is required for the maintenance of vascular smooth muscle cell contractile phenotype via sponging miR‐17‐5P/ATOH8 axis	1
Coexisting bacterial aminoacyl‐tRNAsynthetase paralogs exhibit distinct phylogenetic backgrounds and functional compatibility withEscherichia coli	1
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POBS Relieves Antigen‐Induced Experimental S jögren's Disease by Regulating B	1
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OTUD1 Relieves Coxsackievirus‐Induced Ferroptosis and Inflammation in Myocardial Cells by Stabilizing NRF2 and Inhibit	1
AdipoRon Suppresses Multiple Myeloma Proliferation Through AMPK ‐Mediated Metabolic Reprogramming and Apoptosis Induct	1
Microtubule depolymerization induces ferroptosis in neuroblastoma cells	1
MyomiRs Expression in Limb Girdle Muscular Dystrophy	1
The latest achievements in biochemistry, biophysics and biotechnology—50 years of history of the Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Poland	1
Genetic tools to dissect functions of long noncoding RNAs	1
Bioinformatics‐Based Exploration of LMO4‐Regulated Hippo Pathway to Reverse Adriamycin Resistance in Breast Cancer	1
A hub for regulation of mitochondrial metabolism: Fatty acid and lipoic acid biosynthesis	1