Journal of Translational Medicine

Article	Citations
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	357
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	288
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients	241
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation	194
A call to reignite the revolutionary spirit of scientific discovery	191
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients	185
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study	175
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway	172
Precision information extraction for rare disease epidemiology at scale	170
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	168
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	166
A 3-tier information fusioned framework featuring explainable deep active optimized CRNet for accurate heart disease prediction	163
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	160
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	158
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy	153
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1	153
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer	145
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke	142
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	139
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance	138
Biological tissue engineering for Fontan failure using decellularized extracellular matrix: a systematic review	135
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	134
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway	133
m6A RNA modification and its emerging roles in diseases: recent advances and therapeutic implications	132
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease	131

A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study	127
Integrated screening for small molecules interfering with PKM2: a drug repurposing strategy against glioblastoma	127
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study	124
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages	123
Genetic pleiotropy underlying obesity and autoimmune disorders: a large-scale cross-trait gwas analysis in European ancestry populations	118
Magnetique: an interactive web application to explore transcriptome signatures of heart failure	118
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati	117
B cell pathways implicate shared genetic architecture between schizophrenia and immune-mediated diseases	116
Radiogenomic MRI biomarkers for noninvasive prediction of GPC3 expression and tumor microenvironment in hepatocellular carcinoma	115
Unlocking the potential of EphA2 with precision-guided cancer therapy: bicycle drug conjugates	115
Maternal DNA methylation signatures of gestational diabetes across all stages of pregnancy	114
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma	113
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils	113
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study	112
Chronic liver diseases aggravate radiation-induced intestinal injury through taurocholic acid dysregulation	111
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice	111
Molecular imaging in gastric cancer: state-of-the-art techniques and emerging opportunities	110
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	109
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	109
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation	107
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial	107
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis	105
RAD21 regulation of the enhancer–promoter chromatin loop of RAD51 promotes PARPi resistance in ovarian cancer	104
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	104
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10	103
The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression	103
Establishment and validation of predictive model of ARDS in critically ill patients	99
Unleashing endogenous regeneration by senolytics	98
Translational potential of GMP-grade human umbilical cord-derived mesenchymal stem cells (UC-MSCs) in traumatic spinal cord injury: a preclinical study in rat	98
Peroxynitrite regulates ER stress-mediated Ca2+ flux to mitochondria characterizing cardiac microvascular ischemia–reperfusion injury associated with hyperhomocysteinemia	98
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition	98
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	97
Multiomics prediction and immunogenic validation of personalized neoantigens in cholangiocarcinoma patients	97
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance	96
An enhanced-permeability amphiphilic nanogel loaded with sulforaphane for synergistic anti-oxidative and anti-ferroptotic therapy of corneal alkali burn	95
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model	95
Dual immunosuppression mechanism induced by PTP1B in colorectal cancer: upregulation of PD-L1 by FOXO1/miR-34C/c-MYC axis and inhibition of the infiltration of CD8(+) T cell by downregulating of CXCL1	95
Deciphering USP8’s pivotal role in cancer: mechanisms, clinical insights and contrasts with its function in pituitary adenomas	93
Red blood cell-derived arginase release in hemolytic uremic syndrome	92
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma	92
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction	91
Targeting macrophages: a novel treatment strategy in solid tumors	91
Removal of aging microenvironment of bone defects can effectively promote bone defect repair	91
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis	90
Lower airway transcriptome signatures in asthma: a newly described cytokine C10orf99 identification	89
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden	89
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer	88
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	85
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma	83
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification	82

Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia	82
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer	81
Functional regulation of GlycoRNA and progress in malignant tumors	79
Pancreatic organoids and organoid-on-a-chip platforms: from disease modeling to precision therapy	79
Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications	78
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma	78
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study	78
Dietary patterns, polygenic risk, and kidney cancer incidence: a UK Biobank cohort study	77
USP5 in cancer: a therapeutic window into metabolism and drug resistance	77
An imaging biomarker to detect non-glucogenic shift in brain energy metabolism in Alzheimer’s disease	76
Translational prioritization of genetically supported candidate targets and pharmacological annotations for chronic lung diseases: a single-cell eQTL-guided multi-cohort study	76
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	75
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation	75
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	75
Deep learning-based 3D leukocyte differentiation using label-free higher harmonic generation microscopy	75
Peripheral nerve repair: innovations and future directions	74
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes	74
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv	74
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	74
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics	74
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	73
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer	73
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases	73
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme	73
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients	73
Advances in gene therapy for mitochondrial genetic disorders: current status and clinical implementation challenges	72
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis	72
Co-stimulatory signal deficiency impairs cytotoxic T lymphocyte function in tumor immune evasion: molecular mechanisms and therapeutic implications	72
C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway	72
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway	71
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation	71
Novel models by machine learning to predict prognosis of breast cancer brain metastases	71
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer	70
Exploring TNFR1: from discovery to targeted therapy development	69
Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration	68
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain	68
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care	68
Targeting lactylation in a novel metabolic-epigenetic-inflammatory axis mitigates inflammation and promotes healing following corneal injury	67
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	67
Immunogenicity of adalimumab in patients with noninfectious uveitis based on therapeutic drug monitoring	67
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	67
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma	67
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	67
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images	66
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology	65
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis	65
Interferon lambda in anti-viral defense and cancer: dual roles, mechanism and therapeutic potential	65
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis	65
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics	65
Ki67 assessment, digital image analysis, and PAM50/Prosigna subtype divergence in early ER-positive breast cancer	65
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway	65
Lactylation of β-catenin promotes non-small cell lung cancer by inhibiting ferroptosis through TCF4-mediated GPX4 transcription	64
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability	64
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	64
Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent	64
The MAFG-AS1/G6PD axis reduces platinum sensitivity in colorectal cancer through pentose phosphate pathway activation	63
IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury	63
Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features	63
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas	63
N6-methyladenosine RNA modified BAIAP2L2 facilitates extracellular vesicles-mediated chemoresistance transmission in gastric cancer	63
Targeting CDH13 as a therapeutic strategy to mitigate pathological ocular angiogenesis	63
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant	62
New insights from a systematic review and meta-analysis on the treatment of difficult-to-treat rheumatoid arthritis	62
Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer	62
The preprogrammed anti-inflammatory phenotypes of CD11chigh macrophages by Streptococcus pneumoniae aminopeptidase N safeguard from allergic asthma	62
Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression	61
Targeting cell membrane sphingolipids: a novel ceramide analog CeY-B1 inhibits migration and invasion in cervical cancer cells	61
Multiomics unravels the complexity of male obesity: a prospective observational study	61
Efficacy of LNP@2DG-DON liposomal nanoparticles in tumor inhibition and immune activation	61
Targeting GPA33 with CAR-macrophages: a novel immunotherapeutic approach for colorectal cancer	61
Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4	60
Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage	60
IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers	60
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model	60
The role and mechanism by which micropeptide WHPP promote refractory wound healing	60
Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression	59
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC	59
Comments on “Unleashing the therapeutic potential of tumor-draining lymph nodes: spotlight on bladder cancer”	59
Dermatological implications of alignment-based de-hosting and bioinformatics pipelines on shotgun microbiome analysis	59
Truncated APC impairs innate immune response by targeting MAVS on mitochondria in colorectal cancer	59

MX1+ effector T cells hyperactivation at the maternal-fetal interface in unexplained recurrent pregnancy loss	58
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements	58
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia	58
Development and validation of radiopathomics models for predicting molecular subtypes and WHO grades in adult-type diffuse gliomas: a multicenter study	58
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system	58
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia	58
Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation	57
PUF, a biflavone monomer, triggers DNA damage through SLC25A15 downregulation and purine metabolic suppression in DLBCL	57
COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1+ neural-progenitor-like tumor cell in driving unfavorable outcome	57
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension	57
Interrelationships and determinants of aging biomarkers in cord blood	57
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition	56
Correction to: Combining functional and morphological retinal vascular characteristics achieves high-precision diagnosis of mild non-proliferative diabetic retinopathy	56
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study	56
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function	56
HPV status shapes T-cell immunoprofiles in oesophageal adenocarcinoma: high regulatory T cell infiltration predicts poor prognosis	56
Innate immune functions of bitter taste receptors across physiological systems	56
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome	56
Effect of vitamin D supplementation on skeletal muscle function and quality of life in patients with chronic intestinal failure: a randomized controlled trial	55
Applications and potential mechanisms of transcranial magnetic stimulation in autism spectrum disorders	55
Integrative multi-omics analysis proposes a metabolic classification of gliomas: distinct metabolic states, immune infiltration, and prognosis	55
Role of TLR7 expression in cancer: impact on immune activation and prognostic evaluation	55
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures	55
Function and mechanism of GBP1 in the development and progression of cervical cancer	55
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer	55
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?	55
HERVs may perform as the initial trigger for acquired aplastic anemia	54
Strain-level characterization of bacterial pathogens using metagenomic sequencing for patients with pneumonia	54
Current strategies employed in the manipulation of gene expression for clinical purposes	54
PPARγ signalling pathway: molecular mechanisms and therapeutic potential in ligamentum flavum hypertrophy and lumbar spinal stenosis	54
Multiphasic blood transcriptomic signatures of radioprotection by BIO 300, a synthetic genistein nanosuspension, in a nonhuman primate model of acute radiation syndrome	54
The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease	54
Meta-analysis of comparing CAR-T and bispecific antibody therapy in relapsed/refractory indolent B-cell non-Hodgkin’s lymphomas	54
Microglial dysregulation and spatiotemporal dynamics of inflammation in multiple sclerosis white matter: an integrative transcriptomic analysis	54
The oncogenic potential of SOX12: a comprehensive and perspective view	54
Mesenchymal stem cells can prevent or promote the progression of colon cancer based on their timing of administration	54
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma	53
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders	53
Exploring epigenome-proteome interactions underlying post-surgical progression of non-functioning pituitary adenomas using hypernetwork modelling	53
Low-dose MyoAAV 2A-mediated delivery of engineered micro-utrophin achieves pan- muscle tissue distribution with elevated muscle function in Duchenne muscular dystrophy	53
The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study	53
Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate	53
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression	53
Efficacy and cortical mechanisms of repetitive peripheral magnetic stimulation in non-specific neck and low back pain: a prospective, two-center, randomized, sham-controlled fNIRS study	53
Efficacy of mesenchymal stem cell transplantation on major adverse cardiovascular events and cardiac function indices in patients with chronic heart failure: a meta-analysis of randomized controlled t	52
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke	52
Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions	52
Cyclosporine A promotes renal fibrosis through activating endoplasmic reticulum stress by targeting miR-212-5p/ATF6 axis	52
Reframing ME/CFS: toward a unified mechanistic model of chronic post-infectious diseases	52
CM512, a potentially novel IgG1-based bispecific antibody dual-targeting TSLP and IL-13, for the suppression of type 2 inflammation	52
NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling	52
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1	52
METTL3-driven m6A modification promotes tumor progression and immune evasion in hypoxic pancreatic cancer by enhancing ADAM10-mediated MICA shedding	51
RETRACTED ARTICLE: Peptide hydrogel platform encapsulating manganese ions and high-density lipoprotein nanoparticle-mimicking nanovaccines for the prevention and treatment of gastric cancer	51
Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: evidence from a real-world cohort	51
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer	51
Methylation regulatory networks in osteoarthritis: mechanisms and targeted therapies	51
CR1(+) tumor-associated macrophages orchestrate an immunosuppressive niche in hepatocellular carcinoma: a genetic and multi-omics dissection	51
Good practice in medicine and biology: scientific integrity needs global bioethics	51
Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis	51
CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway	51
A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort	51
Association between the new TyG indicator–TyHGB and gestational diabetes mellitus: results from the case–control and prospective cohort studies	50
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens	50
IL1β+ macrophages promote intestinal fibrosis in Crohn’s disease by secreting AREG to activate PI16+ fibroblasts	50
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization	50
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases	50
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis	50
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury	50
CD8+ T cell-based cancer immunotherapy	50
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis	49
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota	49
NK cell infusion is well-tolerated and shows preliminary efficacy in patients with recurrent hepatocellular carcinoma post-liver transplantation : a phase I trial	49
Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription	49
A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice	49
Low-intensity pulsed ultrasound for peripheral nerve regeneration: mechanobiological mechanisms and translational potential	49
KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway	49
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study	49
The role of PPP2R1A variants in gynecologic malignancies: a paradigm shift in immuno-oncology	49
Clinical trial landscape for periodontitis treatment: Trend analysis and future perspectives	48
CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia	48
RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway	48
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1	48
Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N6-methyladenosine modification of sclerostin	48
Metabolic vulnerability index and MetaboHealth score as risk factors for age-related macular degeneration in a large-scale prospective cohort	48
CD155 reprograms glycolysis via the YAP/TEAD1-GLUT1 axis to promote lung adenocarcinoma progression and M2 macrophage polarization: a metabolic-immune target visualized by 18F-FDG PET/CT	48
Fetal and obstetrics manifestations of mitochondrial diseases	48
Integrated analysis of single-cell and bulk RNA sequencing data reveals a myeloid cell-related regulon predicting neoadjuvant immunotherapy response across cancers	47
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer	47
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia	47
FASN for diffuse malignant peritoneal mesothelioma: a prognostic biomarker after CRS+HIPEC and a therapeutic target	47
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells	47
Tyrosine kinase signaling-independent MET-targeting with CAR-T cells	47
METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression	47
Uridine metabolism promotes lung adenocarcinoma progression by activating FBL transcription via YBX1	47