Journal of Translational Medicine

Papers
(The TQCC of Journal of Translational Medicine is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma267
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway238
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology221
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation219
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers193
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers185
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses184
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism177
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis148
Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications142
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images139
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages136
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer135
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance134
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury129
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis127
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma126
A call to reignite the revolutionary spirit of scientific discovery126
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma124
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients123
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification120
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies117
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study116
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati115
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia112
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients111
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation111
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma110
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment108
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study103
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study103
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine100
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation99
Global research trends on the links between the gut microbiome and cancer: a visualization analysis99
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study98
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles98
Dietary patterns, polygenic risk, and kidney cancer incidence: a UK Biobank cohort study97
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model97
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L197
VLCKD: a real time safety study in obesity95
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases91
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity90
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome90
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation90
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer89
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis89
Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia88
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway88
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition87
Peroxynitrite regulates ER stress-mediated Ca2+ flux to mitochondria characterizing cardiac microvascular ischemia–reperfusion injury associated with hyperhomocysteinemia86
Novel models by machine learning to predict prognosis of breast cancer brain metastases86
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study85
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease85
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis81
Immunogenicity of adalimumab in patients with noninfectious uveitis based on therapeutic drug monitoring80
The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression80
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable80
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling78
Establishment and validation of predictive model of ARDS in critically ill patients76
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma74
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul74
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation74
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden73
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis72
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults72
Magnetique: an interactive web application to explore transcriptome signatures of heart failure71
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis71
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers71
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis70
Red blood cell-derived arginase release in hemolytic uremic syndrome70
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions70
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils69
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain69
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway69
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme68
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN67
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients67
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer67
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care67
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer67
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology67
Unleashing endogenous regeneration by senolytics67
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study66
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction65
Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models65
Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control65
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance64
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway64
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke64
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes64
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics64
Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alte64
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis63
SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner63
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer63
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice63
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma63
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway62
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation62
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics61
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial61
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer60
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv60
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy59
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis59
C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway58
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer58
Exploring TNFR1: from discovery to targeted therapy development58
Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration58
Targeting macrophages: a novel treatment strategy in solid tumors57
Sodium tanshinone IIA sulfonate promotes proliferation and differentiation of endogenous neural stem cells to repair rat spinal cord injury via the Notch pathway57
Precision information extraction for rare disease epidemiology at scale57
Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent57
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP1057
Integrated analysis of single-cell and bulk RNA sequencing data reveals a myeloid cell-related regulon predicting neoadjuvant immunotherapy response across cancers57
Role of TLR7 expression in cancer: impact on immune activation and prognostic evaluation56
Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer56
Correction to: Combining functional and morphological retinal vascular characteristics achieves high-precision diagnosis of mild non-proliferative diabetic retinopathy56
Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization55
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability55
The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease55
Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions55
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients54
A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study54
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension54
A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice54
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome53
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression53
Good practice in medicine and biology: scientific integrity needs global bioethics53
The preprogrammed anti-inflammatory phenotypes of CD11chigh macrophages by Streptococcus pneumoniae aminopeptidase N safeguard from allergic asthma51
Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer51
Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features51
METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression51
New insights from a systematic review and meta-analysis on the treatment of difficult-to-treat rheumatoid arthritis51
CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia51
Recent advances in osteonecrosis of the femoral head: a focus on mesenchymal stem cells and adipocytes50
Strain-level characterization of bacterial pathogens using metagenomic sequencing for patients with pneumonia50
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer50
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function50
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study49
Multiomics unravels the complexity of male obesity: a prospective observational study49
Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B49
Advancing personalized medicine in brain cancer: exploring the role of mRNA vaccines48
IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury48
Development and validation of radiopathomics models for predicting molecular subtypes and WHO grades in adult-type diffuse gliomas: a multicenter study48
Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: evidence from a real-world cohort48
RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway48
NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling47
Clinical trial landscape for periodontitis treatment: Trend analysis and future perspectives47
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine47
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC47
Transformative advances in single-cell omics: a comprehensive review of foundation models, multimodal integration and computational ecosystems47
CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway47
Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage46
The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study46
Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N6-methyladenosine modification of sclerostin46
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score46
Current strategies employed in the manipulation of gene expression for clinical purposes46
Function and mechanism of GBP1 in the development and progression of cervical cancer46
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA546
N6-methyladenosine RNA modified BAIAP2L2 facilitates extracellular vesicles-mediated chemoresistance transmission in gastric cancer46
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant46
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia45
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia45
HERVs may perform as the initial trigger for acquired aplastic anemia45
Global prevalence of myasthenia gravis and the effectiveness of common drugs in its treatment: a systematic review and meta-analysis45
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases45
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer45
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?45
Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression45
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer45
Association between pulse pressure, systolic blood pressure and the risk of rapid decline of kidney function among general population without hypertension: results from the China health and retirement45
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT145
Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression44
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization44
Interrelationships and determinants of aging biomarkers in cord blood44
Dermatological implications of alignment-based de-hosting and bioinformatics pipelines on shotgun microbiome analysis44
Efficacy of MET-targeting CAR T cells against glioblastoma patient-derived xenograft models44
IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers44
Macrophage and fibroblast trajectory inference and crosstalk analysis during myocardial infarction using integrated single-cell transcriptomic datasets44
Truncated APC impairs innate immune response by targeting MAVS on mitochondria in colorectal cancer44
Plant-based dietary patterns, genetic predisposition and risk of colorectal cancer: a prospective study from the UK Biobank44
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin43
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition43
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST143
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis43
Fibrosis and bone marrow: understanding causation and pathobiology43
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model43
A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort42
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis42
Fetal and obstetrics manifestations of mitochondrial diseases42
Peptide hydrogel platform encapsulating manganese ions and high-density lipoprotein nanoparticle-mimicking nanovaccines for the prevention and treatment of gastric cancer42
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study42
Mesenchymal stem cells can prevent or promote the progression of colon cancer based on their timing of administration42
Association between the new TyG indicator–TyHGB and gestational diabetes mellitus: results from the case–control and prospective cohort studies42
Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study42
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma41
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements41
Efficacy of mesenchymal stem cell transplantation on major adverse cardiovascular events and cardiac function indices in patients with chronic heart failure: a meta-analysis of randomized controlled t41
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures41
Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy41
COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1+ neural-progenitor-like tumor cell in driving unfavorable outcome41
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas41
Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription41
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system41
Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation41
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury41
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells40
Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis40
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia40
HPV status shapes T-cell immunoprofiles in oesophageal adenocarcinoma: high regulatory T cell infiltration predicts poor prognosis40
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke40
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota40
Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies40
Microbiota medicine: towards clinical revolution40
The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study40
Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate40
Tyrosine kinase signaling-independent MET-targeting with CAR-T cells40
Wnt/β-catenin signaling in the development and therapeutic resistance of non-small cell lung cancer40
Comments on “Unleashing the therapeutic potential of tumor-draining lymph nodes: spotlight on bladder cancer”40
Increased nerve density adversely affects outcome in colorectal cancer and denervation suppresses tumor growth40
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway40
ICH-LR2S2: a new risk score for predicting stroke-associated pneumonia from spontaneous intracerebral hemorrhage39
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism39
MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment39
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)39
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression39
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin39
Blautia coccoides and its metabolic products enhance the efficacy of bladder cancer immunotherapy by promoting CD8+ T cell infiltration39
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens39
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders39
Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics38
LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling38
Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind rando38
Machine learning based metabolomic and genetic profiles for predicting multiple brain phenotypes38
Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing38
Recent advances and applications of mitochondria in tumors and inflammation38
Patient-derived xenograft (PDX) models, applications and challenges in cancer research38
SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer38
The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 202138
Correction: A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity38
CD8+ T cell-based cancer immunotherapy38
Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer38
Role of KLF5 in enhancing ovarian cancer stemness and PARPi resistance: mechanisms and therapeutic targeting38
Single cell analysis identified a basal cell transition state associated with the development and progression of bladder cancer38
Self-learning neural network as a prediction model in non-invasive prenatal testing to detect fetal SNVs38
Transforming heart transplantation care with multi-omics insights37
Meldonium, as a potential neuroprotective agent, promotes neuronal survival by protecting mitochondria in cerebral ischemia–reperfusion injury37
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis37
CIITA-modified glioblastomas vaccinate and induce cross-protection against heterologous wild-type glioblastomas37
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