Journal of Translational Medicine

Papers
(The median citation count of Journal of Translational Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma254
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway229
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology216
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis208
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation187
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv181
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers175
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults169
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers146
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses134
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis133
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism133
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine128
Global research trends on the links between the gut microbiome and cancer: a visualization analysis126
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN126
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance122
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study121
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease120
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling118
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer117
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma116
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance114
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable113
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul107
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury107
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes105
Precision information extraction for rare disease epidemiology at scale104
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis103
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation101
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology100
Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models98
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer98
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy98
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis98
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis96
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway95
Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia92
A call to reignite the revolutionary spirit of scientific discovery90
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction88
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation87
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma86
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis85
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway84
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients84
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification84
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma84
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation83
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis82
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions82
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies81
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study79
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati78
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer78
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia78
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients77
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation76
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma75
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer75
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study74
Red blood cell-derived arginase release in hemolytic uremic syndrome72
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer72
Establishment and validation of predictive model of ARDS in critically ill patients69
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model69
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment69
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study68
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer68
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway67
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients67
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles67
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial67
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation67
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice66
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics66
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics64
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP1064
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study64
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden64
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis64
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study64
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma63
Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control63
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils63
Targeting macrophages: a novel treatment strategy in solid tumors62
Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alte62
Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications61
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke61
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme61
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition60
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images60
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway59
Magnetique: an interactive web application to explore transcriptome signatures of heart failure59
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer58
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages58
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care58
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers58
VLCKD: a real time safety study in obesity57
Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration57
Dexmedetomidine inhibits mitochondria damage and apoptosis of enteric glial cells in experimental intestinal ischemia/reperfusion injury via SIRT3-dependent PINK1/HDAC3/p53 pathway57
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases57
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome57
Exploring TNFR1: from discovery to targeted therapy development57
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis56
SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner56
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L156
C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway56
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity56
Novel models by machine learning to predict prognosis of breast cancer brain metastases56
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain56
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression55
Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent55
Sodium tanshinone IIA sulfonate promotes proliferation and differentiation of endogenous neural stem cells to repair rat spinal cord injury via the Notch pathway55
Integrated analysis of single-cell and bulk RNA sequencing data reveals a myeloid cell-related regulon predicting neoadjuvant immunotherapy response across cancers55
COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1+ neural-progenitor-like tumor cell in driving unfavorable outcome54
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?54
Role of TLR7 expression in cancer: impact on immune activation and prognostic evaluation54
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas54
N6-methyladenosine RNA modified BAIAP2L2 facilitates extracellular vesicles-mediated chemoresistance transmission in gastric cancer53
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis53
Correction to: Combining functional and morphological retinal vascular characteristics achieves high-precision diagnosis of mild non-proliferative diabetic retinopathy53
Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer53
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis53
Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization53
The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease52
Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies51
Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions51
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study51
Tyrosine kinase signaling-independent MET-targeting with CAR-T cells51
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability51
The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study50
Fetal and obstetrics manifestations of mitochondrial diseases50
A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice50
Mesenchymal stem cells can prevent or promote the progression of colon cancer based on their timing of administration49
A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study49
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements49
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients49
Good practice in medicine and biology: scientific integrity needs global bioethics48
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension48
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome48
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST148
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression48
The preprogrammed anti-inflammatory phenotypes of CD11chigh macrophages by Streptococcus pneumoniae aminopeptidase N safeguard from allergic asthma47
Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features47
New insights from a systematic review and meta-analysis on the treatment of difficult-to-treat rheumatoid arthritis47
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury46
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens46
Recent advances in osteonecrosis of the femoral head: a focus on mesenchymal stem cells and adipocytes46
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function46
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota45
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization45
Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage45
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer45
Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis45
Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B45
Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation45
Strain-level characterization of bacterial pathogens using metagenomic sequencing for patients with pneumonia45
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study45
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells44
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer44
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin44
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model44
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders44
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT144
MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment44
Multiomics unravels the complexity of male obesity: a prospective observational study44
Advancing personalized medicine in brain cancer: exploring the role of mRNA vaccines44
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA544
Transformative advances in single-cell omics: a comprehensive review of foundation models, multimodal integration and computational ecosystems43
IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers43
IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury43
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures43
Increased nerve density adversely affects outcome in colorectal cancer and denervation suppresses tumor growth43
Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: evidence from a real-world cohort43
Development and validation of radiopathomics models for predicting molecular subtypes and WHO grades in adult-type diffuse gliomas: a multicenter study43
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine43
RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway43
Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N6-methyladenosine modification of sclerostin42
Peptide hydrogel platform encapsulating manganese ions and high-density lipoprotein nanoparticle-mimicking nanovaccines for the prevention and treatment of gastric cancer42
Clinical trial landscape for periodontitis treatment: Trend analysis and future perspectives42
CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway42
Efficacy of mesenchymal stem cell transplantation on major adverse cardiovascular events and cardiac function indices in patients with chronic heart failure: a meta-analysis of randomized controlled t42
METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression42
Current strategies employed in the manipulation of gene expression for clinical purposes42
Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study42
A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort42
NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling42
Interrelationships and determinants of aging biomarkers in cord blood42
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC42
Macrophage and fibroblast trajectory inference and crosstalk analysis during myocardial infarction using integrated single-cell transcriptomic datasets41
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism41
Fibrosis and bone marrow: understanding causation and pathobiology41
Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer41
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant41
Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer41
HERVs may perform as the initial trigger for acquired aplastic anemia40
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases40
The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study40
Global prevalence of myasthenia gravis and the effectiveness of common drugs in its treatment: a systematic review and meta-analysis40
Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression40
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score40
Wnt/β-catenin signaling in the development and therapeutic resistance of non-small cell lung cancer40
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia40
Function and mechanism of GBP1 in the development and progression of cervical cancer40
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition40
MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS40
Association between pulse pressure, systolic blood pressure and the risk of rapid decline of kidney function among general population without hypertension: results from the China health and retirement39
CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia39
Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics39
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer39
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)39
Association between the new TyG indicator–TyHGB and gestational diabetes mellitus: results from the case–control and prospective cohort studies39
Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy38
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke38
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia38
Plant-based dietary patterns, genetic predisposition and risk of colorectal cancer: a prospective study from the UK Biobank38
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system38
Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate38
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia38
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin38
ICH-LR2S2: a new risk score for predicting stroke-associated pneumonia from spontaneous intracerebral hemorrhage38
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway38
Blautia coccoides and its metabolic products enhance the efficacy of bladder cancer immunotherapy by promoting CD8+ T cell infiltration37
Patient-derived xenograft (PDX) models, applications and challenges in cancer research37
Role of KLF5 in enhancing ovarian cancer stemness and PARPi resistance: mechanisms and therapeutic targeting37
Recent advances and applications of mitochondria in tumors and inflammation37
Towards clinical translation of urinary vitronectin for non-invasive detection and monitoring of renal fibrosis in kidney transplant patients37
Efficacy of MET-targeting CAR T cells against glioblastoma patient-derived xenograft models37
Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription37
LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling37
SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer37
The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 202137
Microbiota medicine: towards clinical revolution37
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma37
CD8+ T cell-based cancer immunotherapy37
Exosome-mediated lncRNA SND1-IT1 from gastric cancer cells enhances malignant transformation of gastric mucosa cells via up-regulating SNAIL137
Adherence to the Mediterranean diet as a possible additional tool to be used for screening the metabolically unhealthy obesity (MUO) phenotype37
Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind rando37
Multi-scale pathology image texture signature is a prognostic factor for resectable lung adenocarcinoma: a multi-center, retrospective study36
Spatiotemporal microenvironment landscape and malignant epithelial pattern transition in breast ductal carcinoma progression36
Correction: A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity36
Letter to editor: detection of immune-mediated tumour cell death in vivo using Zirconium-89-labeled APOMAB®36
Engineered sensor actuator modulator as aqueous humor outflow actuator for gene therapy of primary open-angle glaucoma36
Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer36
Shared neoantigens’ atlas for off-the-shelf cancer vaccine development36
Self-learning neural network as a prediction model in non-invasive prenatal testing to detect fetal SNVs36
Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials36
Decoding m6A RNA methylation in kidney disorders: from molecular insights to therapeutic strategies36
Identifying pathways to cardiovascular mortality by causal graphical models and mediation analysis among hypertensive patients: insights from a prospective study36
Machine learning based metabolomic and genetic profiles for predicting multiple brain phenotypes36
Treg and intestinal myofibroblasts-derived Amphiregulin induced by TGF-β mediates intestinal fibrosis in Crohn’s disease36
Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing36
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