Journal of Translational Medicine

Article	Citations
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	279
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation	243
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	233
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	223
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	198
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	196
Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications	187
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images	186
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer	149
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	145
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma	144
A call to reignite the revolutionary spirit of scientific discovery	144
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients	142
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification	139
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	135
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation	130
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati	130
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients	130
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma	128
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study	125
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	121
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study	121
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance	120
Deciphering USP8’s pivotal role in cancer: mechanisms, clinical insights and contrasts with its function in pituitary adenomas	118
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy	116

The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer	114
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	112
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma	110
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	108
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	107
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model	104
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study	104
Dietary patterns, polygenic risk, and kidney cancer incidence: a UK Biobank cohort study	103
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer	102
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1	102
Peroxynitrite regulates ER stress-mediated Ca2+ flux to mitochondria characterizing cardiac microvascular ischemia–reperfusion injury associated with hyperhomocysteinemia	101
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study	101
Immunogenicity of adalimumab in patients with noninfectious uveitis based on therapeutic drug monitoring	100
The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression	99
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma	98
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	97
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	96
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	95
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	95
Red blood cell-derived arginase release in hemolytic uremic syndrome	94
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients	94
Unleashing endogenous regeneration by senolytics	93
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study	92
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	91
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease	89
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme	89
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway	87
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis	85
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia	82
Integrated screening for small molecules interfering with PKM2: a drug repurposing strategy against glioblastoma	82
Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia	81
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway	80
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden	80
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	80
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition	78
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10	78
Radiogenomic MRI biomarkers for noninvasive prediction of GPC3 expression and tumor microenvironment in hepatocellular carcinoma	76
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial	76
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	75
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases	75
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes	74
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice	73
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer	73
VLCKD: a real time safety study in obesity	73
SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner	72
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN	71
Precision information extraction for rare disease epidemiology at scale	71
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	71
Genetic pleiotropy underlying obesity and autoimmune disorders: a large-scale cross-trait gwas analysis in European ancestry populations	71
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis	71

Advancing polytrauma care: developing and validating machine learning models for early mortality prediction	70
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics	70
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology	70
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis	69
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling	69
C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway	69
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma	69
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	69
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma	69
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation	68
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv	68
Advances in gene therapy for mitochondrial genetic disorders: current status and clinical implementation challenges	67
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer	67
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation	67
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics	66
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation	66
Maternal DNA methylation signatures of gestational diabetes across all stages of pregnancy	66
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis	65
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages	65
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study	65
Global research trends on the links between the gut microbiome and cancer: a visualization analysis	65
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis	64
Magnetique: an interactive web application to explore transcriptome signatures of heart failure	64
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke	64
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils	63
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome	63
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	62
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway	62
Exploring TNFR1: from discovery to targeted therapy development	62
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway	60
Targeting macrophages: a novel treatment strategy in solid tumors	59
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance	59
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care	59
Establishment and validation of predictive model of ARDS in critically ill patients	58
Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration	58
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers	58
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain	58
Novel models by machine learning to predict prognosis of breast cancer brain metastases	58
Correction to: Combining functional and morphological retinal vascular characteristics achieves high-precision diagnosis of mild non-proliferative diabetic retinopathy	57
Sodium tanshinone IIA sulfonate promotes proliferation and differentiation of endogenous neural stem cells to repair rat spinal cord injury via the Notch pathway	57
Role of TLR7 expression in cancer: impact on immune activation and prognostic evaluation	57
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis	57
Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer	57
Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent	57
Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization	56
The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease	56
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability	56
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism	55
Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy	55
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model	54
Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4	54
A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice	54
Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics	54
Efficacy of mesenchymal stem cell transplantation on major adverse cardiovascular events and cardiac function indices in patients with chronic heart failure: a meta-analysis of randomized controlled t	53
METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression	53
IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers	53
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway	52
RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway	52
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens	52
ICH-LR2S2: a new risk score for predicting stroke-associated pneumonia from spontaneous intracerebral hemorrhage	52
Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions	51
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas	51
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures	51
MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment	51
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia	51
CD155 reprograms glycolysis via the YAP/TEAD1-GLUT1 axis to promote lung adenocarcinoma progression and M2 macrophage polarization: a metabolic-immune target visualized by 18F-FDG PET/CT	50
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression	50
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system	49
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?	49
Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis	49
A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study	49
Current strategies employed in the manipulation of gene expression for clinical purposes	49
Fibrosis and bone marrow: understanding causation and pathobiology	48
Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription	48
Plant-based dietary patterns, genetic predisposition and risk of colorectal cancer: a prospective study from the UK Biobank	48
Macrophage and fibroblast trajectory inference and crosstalk analysis during myocardial infarction using integrated single-cell transcriptomic datasets	48
N6-methyladenosine RNA modified BAIAP2L2 facilitates extracellular vesicles-mediated chemoresistance transmission in gastric cancer	48
NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling	48
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders	48
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin	48

Effect of vitamin D supplementation on skeletal muscle function and quality of life in patients with chronic intestinal failure: a randomized controlled trial	48
Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies	48
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression	48
Function and mechanism of GBP1 in the development and progression of cervical cancer	47
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension	47
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells	47
Good practice in medicine and biology: scientific integrity needs global bioethics	47
Meta-analysis of comparing CAR-T and bispecific antibody therapy in relapsed/refractory indolent B-cell non-Hodgkin’s lymphomas	47
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome	47
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements	47
Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features	46
Recent advances in osteonecrosis of the femoral head: a focus on mesenchymal stem cells and adipocytes	46
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study	46
The preprogrammed anti-inflammatory phenotypes of CD11chigh macrophages by Streptococcus pneumoniae aminopeptidase N safeguard from allergic asthma	46
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function	46
Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B	46
New insights from a systematic review and meta-analysis on the treatment of difficult-to-treat rheumatoid arthritis	46
Development and validation of radiopathomics models for predicting molecular subtypes and WHO grades in adult-type diffuse gliomas: a multicenter study	45
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC	45
IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury	45
CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway	45
Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: evidence from a real-world cohort	45
Transformative advances in single-cell omics: a comprehensive review of foundation models, multimodal integration and computational ecosystems	45
Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N6-methyladenosine modification of sclerostin	45
Truncated APC impairs innate immune response by targeting MAVS on mitochondria in colorectal cancer	44
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study	44
HPV status shapes T-cell immunoprofiles in oesophageal adenocarcinoma: high regulatory T cell infiltration predicts poor prognosis	44
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization	44
Blautia coccoides and its metabolic products enhance the efficacy of bladder cancer immunotherapy by promoting CD8+ T cell infiltration	44
Comments on “Unleashing the therapeutic potential of tumor-draining lymph nodes: spotlight on bladder cancer”	44
Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation	44
COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1+ neural-progenitor-like tumor cell in driving unfavorable outcome	44
Tyrosine kinase signaling-independent MET-targeting with CAR-T cells	44
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis	44
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia	43
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine	43
Interrelationships and determinants of aging biomarkers in cord blood	43
Fetal and obstetrics manifestations of mitochondrial diseases	43
Strain-level characterization of bacterial pathogens using metagenomic sequencing for patients with pneumonia	43
Dermatological implications of alignment-based de-hosting and bioinformatics pipelines on shotgun microbiome analysis	43
Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer	43
Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression	43
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer	43
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1	43
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis	42
Advancing personalized medicine in brain cancer: exploring the role of mRNA vaccines	42
Peptide hydrogel platform encapsulating manganese ions and high-density lipoprotein nanoparticle-mimicking nanovaccines for the prevention and treatment of gastric cancer	42
Integrated analysis of single-cell and bulk RNA sequencing data reveals a myeloid cell-related regulon predicting neoadjuvant immunotherapy response across cancers	42
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia	42
Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer	42
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score	42
Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression	42
Efficacy of MET-targeting CAR T cells against glioblastoma patient-derived xenograft models	42
The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study	42
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer	42
Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage	42
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients	42
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer	42
Mesenchymal stem cells can prevent or promote the progression of colon cancer based on their timing of administration	42
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition	41
Multiomics unravels the complexity of male obesity: a prospective observational study	41
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin	41
HERVs may perform as the initial trigger for acquired aplastic anemia	41
A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort	41
Integrative multi-omics analysis proposes a metabolic classification of gliomas: distinct metabolic states, immune infiltration, and prognosis	41
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant	41
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma	41
The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study	40
Increased nerve density adversely affects outcome in colorectal cancer and denervation suppresses tumor growth	40
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases	40
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)	40
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5	40
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1	40
Low-intensity pulsed ultrasound for peripheral nerve regeneration: mechanobiological mechanisms and translational potential	40
Microbiota medicine: towards clinical revolution	40
CD8+ T cell-based cancer immunotherapy	40
Wnt/β-catenin signaling in the development and therapeutic resistance of non-small cell lung cancer	40
Clinical trial landscape for periodontitis treatment: Trend analysis and future perspectives	40
CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia	40
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota	40
Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate	40
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke	40
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury	40
Recent advances and applications of mitochondria in tumors and inflammation	39
Role of KLF5 in enhancing ovarian cancer stemness and PARPi resistance: mechanisms and therapeutic targeting	39
Machine learning based metabolomic and genetic profiles for predicting multiple brain phenotypes	39
Letter to editor: detection of immune-mediated tumour cell death in vivo using Zirconium-89-labeled APOMAB®	39
Patient-derived xenograft (PDX) models, applications and challenges in cancer research	39
The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 2021	39
Correction: A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	39
Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind rando	39
Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study	39
Association between the new TyG indicator–TyHGB and gestational diabetes mellitus: results from the case–control and prospective cohort studies	39
Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing	39
Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming	38