OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Translational Medicine is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Heparin-binding growth factor (HDGF) drives radioresistance in breast cancer by activating the STAT3 signaling pathway	282
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN	191
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma	178
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	173
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer	168
Magnetique: an interactive web application to explore transcriptome signatures of heart failure	162
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10	158
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	153
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	137
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study	122
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati	119
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils	111
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	107
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	107
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	105
Red blood cell-derived arginase release in hemolytic uremic syndrome	105
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme	98
Development and validation of new screening tool for predicting dementia risk in community-dwelling older Japanese adults	97
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling	94
Global research trends on the links between the gut microbiome and cancer: a visualization analysis	92
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study	90
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation	90
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance	89
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden	87
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care	87

MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	84
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	84
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer	83
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	83
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	82
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	80
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis	80
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy	78
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	77
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	75
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	74
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	74
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study	73
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation	72
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study	71
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	71
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	70
Establishment and validation of predictive model of ARDS in critically ill patients	70
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	70
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes	67
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1	67
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome	66
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	66
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images	65
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain	65
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	65
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance	63
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer	62
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	62
Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alte	61
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study	61
What can the neurological manifestations of COVID-19 tell us: a meta-analysis	60
VLCKD: a real time safety study in obesity	60
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia	59