OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Proteomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	78
Proteomics in support of immunotherapy: contribution to model-based precision medicine	54
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	37
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	35
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	23
Proteomic profiling and network biology of colorectal cancer liver metastasis	23
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	22
Oncoproteomic profiling of AML: moving beyond genomics	22
Omics and rare diseases: challenges, applications, and future perspectives	19
Positional proteomics: is the technology ready to study clinical cohorts?	17
Mapping the human brain proteome: opportunities, challenges, and clinical potential	17
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	16
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	16
The method developer’s guide to oligonucleotide design	16
Proteomic tools to study phosphorylation of intrinsically disordered proteins	14
Utilizing databases for astrocyte secretome research	11
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	10
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	10
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	10
Proteomic profiling of cerebrospinal fluid reveals pathophysiology changes and diversity of treatment response in pediatric Streptococcus pneumoniae meningitis	10
Recent advances in mass spectrometry for the detection of doping	8
Role of structural disorder in the multi-functionality of flavivirus proteins	8
A Galaxy of informatics resources for MS-based proteomics	8
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	8
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	7

Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	7
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	6
The evolution of analytical techniques for multiplex analysis of protein biomarkers	6
Analyzing the glial proteome in Alzheimer’s disease	6
How to maximize power for differential expression analysis in discovery omics through experimental design	6
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	6
Proteomic interrogation of the human olfactory system: the road ahead	6
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	6
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	6
Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies	5
Evaluation of a ‘plug and play’ nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens	5
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	5
How glycomic studies can impact on prostate cancer	5
Glycosylation in cancer as a source of biomarkers	5
Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad	5
Integrative analysis of proteomic and MRI data reveals protein associations with brain imaging features in Alzheimer’s disease	5
Advances in the clinical use of metaproteomics	5
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	5
Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy	5
The role of E3 ubiquitin ligase in multiple myeloma: potential for cereblon E3 ligase modulators in the treatment of relapsed/refractory disease	5
Tackling reproducibility: lessons for the proteomics community	5