OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Proteomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
An overview of multiplexed analyses of CAR T-cell therapies: insights and potential	70
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	47
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	34
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	32
Proteomic profiling and network biology of colorectal cancer liver metastasis	31
Proteomics in support of immunotherapy: contribution to model-based precision medicine	29
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	28
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	22
Oncoproteomic profiling of AML: moving beyond genomics	21
The role of proteomics in the multiplexed analysis of gene alterations in human cancer	21
Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice	20
Positional proteomics: is the technology ready to study clinical cohorts?	20
Omics and rare diseases: challenges, applications, and future perspectives	20
Mapping the human brain proteome: opportunities, challenges, and clinical potential	20
The method developer’s guide to oligonucleotide design	17
Protein lysine acetylation and its role in different human pathologies: a proteomic approach	17
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	15
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	15
Utilizing databases for astrocyte secretome research	13
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	13
Proteomic tools to study phosphorylation of intrinsically disordered proteins	13
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	11
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	9
A Galaxy of informatics resources for MS-based proteomics	9
Role of structural disorder in the multi-functionality of flavivirus proteins	9

Recent advances in mass spectrometry for the detection of doping	9
Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	9
Proteomic profiling of cerebrospinal fluid reveals pathophysiology changes and diversity of treatment response in pediatric Streptococcus pneumoniae meningitis	8
Analyzing the glial proteome in Alzheimer’s disease	8
Replication of single-cell proteomics data reveals important computational challenges	8
Proteomic interrogation of the human olfactory system: the road ahead	8
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	8
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	8
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	7
How to maximize power for differential expression analysis in discovery omics through experimental design	6
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	6
The evolution of analytical techniques for multiplex analysis of protein biomarkers	6
Advances in the proteomic profiling of the matrisome and adhesome	6
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	6
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	5
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	5
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	5
Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies	5
Advances in the clinical use of metaproteomics	5