OOIR: Observatory of International Research

Papers

(The median citation count of Expert Review of Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
An overview of multiplexed analyses of CAR T-cell therapies: insights and potential	70
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	47
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	34
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	32
Proteomic profiling and network biology of colorectal cancer liver metastasis	31
Proteomics in support of immunotherapy: contribution to model-based precision medicine	29
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	28
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	22
The role of proteomics in the multiplexed analysis of gene alterations in human cancer	21
Oncoproteomic profiling of AML: moving beyond genomics	21
Mapping the human brain proteome: opportunities, challenges, and clinical potential	20
Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice	20
Positional proteomics: is the technology ready to study clinical cohorts?	20
Omics and rare diseases: challenges, applications, and future perspectives	20
Protein lysine acetylation and its role in different human pathologies: a proteomic approach	17
The method developer’s guide to oligonucleotide design	17
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	15
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	15
Proteomic tools to study phosphorylation of intrinsically disordered proteins	13
Utilizing databases for astrocyte secretome research	13
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	13
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	11
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	9
A Galaxy of informatics resources for MS-based proteomics	9
Role of structural disorder in the multi-functionality of flavivirus proteins	9

Recent advances in mass spectrometry for the detection of doping	9
Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	9
Proteomic profiling of cerebrospinal fluid reveals pathophysiology changes and diversity of treatment response in pediatric Streptococcus pneumoniae meningitis	8
Analyzing the glial proteome in Alzheimer’s disease	8
Replication of single-cell proteomics data reveals important computational challenges	8
Proteomic interrogation of the human olfactory system: the road ahead	8
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	8
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	8
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	7
How to maximize power for differential expression analysis in discovery omics through experimental design	6
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	6
The evolution of analytical techniques for multiplex analysis of protein biomarkers	6
Advances in the proteomic profiling of the matrisome and adhesome	6
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	6
Advances in the clinical use of metaproteomics	5
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	5
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	5
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	5
Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies	5
Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy	4
Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad	4
Recent implementations of data-independent acquisition for cancer biomarker discovery in biological fluids	4
How glycomic studies can impact on prostate cancer	4
Evaluation of a ‘plug and play’ nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens	4
Proteomic profiling of carbonic anhydrase CA3 in skeletal muscle	4
Tackling reproducibility: lessons for the proteomics community	4
Interaction and regulation of the mitochondrial proteome – in health and disease	4
The role of E3 ubiquitin ligase in multiple myeloma: potential for cereblon E3 ligase modulators in the treatment of relapsed/refractory disease	4
Mass spectrometry based metabolomics for small molecule metabolites mining and confirmation as potential biomarkers for schistosomiasis – case of the Okavango Delta communities in Botswana	4
Glycosylation in cancer as a source of biomarkers	4
Role of protein deimination in cardiovascular diseases: potential new avenues for diagnostic and prognostic biomarkers	3
Metabolomics in diabetes mellitus: clinical insight	3
Neuroproteomic mapping of kinases and their substrates downstream of acetylcholine: finding and implications	3
Mapping the human sperm proteome – novel insights into reproductive research	3
Immobilized metal ion affinity chromatography: waltz of metal ions and biomacromolecules	3
Single-cell omics techniques to elucidate cell-to-cell variability in signalling cascades involved in human diseases	3
Blood plasma proteomic markers of Alzheimer’s disease, current status and application prospects	3
How can proteomics be incorporated into the management of atrial fibrillation?	3
Rise of the SARS-CoV-2 Variants: can proteomics be the silver bullet?	3
AlphaFold and what is next: bridging functional, systems and structural biology	3
How valuable can proteogenomics be in clinical breast cancer research?	3
Reverse phase protein arrays in acute leukemia: investigative and methodological challenges	3
Proteolytic signaling in cancer	3
Glycoproteomic contributions to hepatocellular carcinoma research: a 2023 update	3
Genetic signatures of suicide attempt behavior: insights and applications	3
Proteomics in the study of female fertility: an update	3
Urine proteomics in cardiovascular disease: advances in biomarker discovery and clinical applications	3
Metabolomics studies in cushing’s syndrome: recent developments and perspectives	3
A proteome-level view of brain tumors for a better understanding of novel diagnosis, prognosis, and therapy	3
Oncoproteins E6/E7 of the human papillomavirus types 16 & 18 synergize in modulating oncogenes and tumor suppressor proteins in colorectal cancer	3

Human bronchial-pulmonary proteomics in coronavirus disease 2019 (COVID-19) pandemic: applications and implications	3
Identifying therapeutic strategies for triple-negative breast cancer via phosphoproteomics	2
Understanding the age-related alterations in the testis-specific proteome	2
Noninvasive urine metabolomics of prostate cancer and its therapeutic approaches: a current scenario and future perspective	2
Cellular thermal shift assay: an approach to identify and assess protein target engagement	2
Emerging protein sequencing technologies: proteomics without mass spectrometry?	2
Deciphering a proteomic signature for the early detection of breast cancer from breast milk: the role of quantitative proteomics	2
Proteomic scrutiny of nasal microbiomes: implications for the clinic	2
Proteomic technologies for profiling cell-membrane/secretome interactions in brain metastatic cancer progression	2
Schistosome proteomics: updates and clinical implications	2
HDL proteome: from its characterization to quantitative measurements in particle subspecies and functional associations	2
Recent progress in quantitative phosphoproteomics	2
Spatial Proteomics towards cellular Resolution	2
Empowering women and addressing underrepresentation in the field of mass spectrometry	2
Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions	2
Protein markers of spermatogenesis and their potential use in the management of azoospermia	2
Proteomics and phosphoproteomics analysis of tissues for the reoccurrence prediction of colorectal cancer	2
Two decades of advances in sequence-based prediction of MoRFs, disorder-to-order transitioning binding regions	2
Proteomics applications in next generation induced pluripotent stem cell models	2
Proteomic approaches for untangling pharmacological targets in acute myelogenous leukemia	2
Laser Capture Proteomics: spatial tissue molecular profiling from the bench to personalized medicine	2