OOIR: Observatory of International Research

Papers

(The median citation count of Expert Review of Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	76
Proteomics in support of immunotherapy: contribution to model-based precision medicine	52
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	35
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	35
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	23
Proteomic profiling and network biology of colorectal cancer liver metastasis	23
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	21
Omics and rare diseases: challenges, applications, and future perspectives	21
Oncoproteomic profiling of AML: moving beyond genomics	21
Mapping the human brain proteome: opportunities, challenges, and clinical potential	19
Positional proteomics: is the technology ready to study clinical cohorts?	17
The method developer’s guide to oligonucleotide design	17
Protein lysine acetylation and its role in different human pathologies: a proteomic approach	16
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	15
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	14
Utilizing databases for astrocyte secretome research	13
Proteomic tools to study phosphorylation of intrinsically disordered proteins	10
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	10
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	10
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	9
Role of structural disorder in the multi-functionality of flavivirus proteins	9
Proteomic profiling of cerebrospinal fluid reveals pathophysiology changes and diversity of treatment response in pediatric Streptococcus pneumoniae meningitis	9
Recent advances in mass spectrometry for the detection of doping	8
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	8
A Galaxy of informatics resources for MS-based proteomics	8

Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	8
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	6
How to maximize power for differential expression analysis in discovery omics through experimental design	6
Proteomic interrogation of the human olfactory system: the road ahead	6
Advances in the clinical use of metaproteomics	6
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	6
Analyzing the glial proteome in Alzheimer’s disease	6
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	6
The evolution of analytical techniques for multiplex analysis of protein biomarkers	5
Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy	5
Glycosylation in cancer as a source of biomarkers	5
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	5
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	5
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	5
How glycomic studies can impact on prostate cancer	5
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	5
Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies	5
Tackling reproducibility: lessons for the proteomics community	5
Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad	4
Mass spectrometry based metabolomics for small molecule metabolites mining and confirmation as potential biomarkers for schistosomiasis – case of the Okavango Delta communities in Botswana	4
Neuroproteomic mapping of kinases and their substrates downstream of acetylcholine: finding and implications	4
Metabolomics in diabetes mellitus: clinical insight	4
Evaluation of a ‘plug and play’ nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens	4
Proteomic profiling of carbonic anhydrase CA3 in skeletal muscle	4
Proteomics in the study of female fertility: an update	4
Role of protein deimination in cardiovascular diseases: potential new avenues for diagnostic and prognostic biomarkers	4
Recent implementations of data-independent acquisition for cancer biomarker discovery in biological fluids	4
The role of E3 ubiquitin ligase in multiple myeloma: potential for cereblon E3 ligase modulators in the treatment of relapsed/refractory disease	4
Urine proteomics in cardiovascular disease: advances in biomarker discovery and clinical applications	4
Genetic signatures of suicide attempt behavior: insights and applications	4
Interaction and regulation of the mitochondrial proteome – in health and disease	4
Reverse phase protein arrays in acute leukemia: investigative and methodological challenges	3
How valuable can proteogenomics be in clinical breast cancer research?	3
How can proteomics be incorporated into the management of atrial fibrillation?	3
MRMAssayDB: a comprehensive integrated resource for targeted proteomics assays	3
Oncoproteins E6/E7 of the human papillomavirus types 16 & 18 synergize in modulating oncogenes and tumor suppressor proteins in colorectal cancer	3
Human bronchial-pulmonary proteomics in coronavirus disease 2019 (COVID-19) pandemic: applications and implications	3
Deciphering a proteomic signature for the early detection of breast cancer from breast milk: the role of quantitative proteomics	3
Mapping the human sperm proteome – novel insights into reproductive research	3
Rise of the SARS-CoV-2 Variants: can proteomics be the silver bullet?	3
Toward real clinical utility: leveraging comprehensive proteomic datasets for clinical insight	3
Blood plasma proteomic markers of Alzheimer’s disease, current status and application prospects	3
Single-cell omics techniques to elucidate cell-to-cell variability in signalling cascades involved in human diseases	3
Recent progress in quantitative phosphoproteomics	3
A proteome-level view of brain tumors for a better understanding of novel diagnosis, prognosis, and therapy	3
Immobilized metal ion affinity chromatography: waltz of metal ions and biomacromolecules	3
Metabolomics studies in cushing’s syndrome: recent developments and perspectives	3
AlphaFold and what is next: bridging functional, systems and structural biology	3
Proteolytic signaling in cancer	3
Glycoproteomic contributions to hepatocellular carcinoma research: a 2023 update	3

Noninvasive urine metabolomics of prostate cancer and its therapeutic approaches: a current scenario and future perspective	3
HDL proteome: from its characterization to quantitative measurements in particle subspecies and functional associations	2
Two decades of advances in sequence-based prediction of MoRFs, disorder-to-order transitioning binding regions	2
Schistosome proteomics: updates and clinical implications	2
Spatial Proteomics towards cellular Resolution	2
Proteomic scrutiny of nasal microbiomes: implications for the clinic	2
Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions	2
Understanding the age-related alterations in the testis-specific proteome	2
Cellular thermal shift assay: an approach to identify and assess protein target engagement	2
Proteomic technologies for profiling cell-membrane/secretome interactions in brain metastatic cancer progression	2
Advances in phosphoproteomics and its application to COPD	2
Emerging protein sequencing technologies: proteomics without mass spectrometry?	2
Identifying therapeutic strategies for triple-negative breast cancer via phosphoproteomics	2
Proteomic approaches for untangling pharmacological targets in acute myelogenous leukemia	2
Protein markers of spermatogenesis and their potential use in the management of azoospermia	2
An overview of metabolomic and proteomic profiling in bipolar disorder and its clinical value	2
Proteomics applications in next generation induced pluripotent stem cell models	2
Liquid-phase separations coupled with ion mobility-mass spectrometry for next-generation biopharmaceutical analysis	2
Proteomics and phosphoproteomics analysis of tissues for the reoccurrence prediction of colorectal cancer	2
Empowering women and addressing underrepresentation in the field of mass spectrometry	2