Cell Communication and Signaling

Article	Citations
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC	343
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells	268
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress	261
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor	198
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish	174
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2	153
Epigenetic meets metabolism: novel vulnerabilities to fight cancer	152
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling	152
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice	136
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	127
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2	125
Phase separation-mediated biomolecular condensates and their relationship to tumor	114
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma	105
Catalase-deficient mice induce aging faster through lysosomal dysfunction	105
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types	102
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer	98
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases	93
The scaffold protein AXIN1: gene ontology, signal network, and physiological function	86
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation	82
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury	77
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression	77
Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response	77
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1	75
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence	74
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage	71

Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases	70
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells	70
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology	68
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	67
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis	66
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice	63
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis	63
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment	62
The role of lactate in cardiovascular diseases	60
New insights into the regulation of METTL3 and its role in tumors	58
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction	57
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster	57
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice	55
Microglial depletion decreases Müller cell maturation and inner retinal vascular density	54
O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology	53
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways	52
MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis	52
Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells	51
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone m	50
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis	50
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis	49
Roles of Twist1 in lipid and glucose metabolism	49
Patient-derived scaffolds influence secretion profiles in cancer cells mirroring clinical features and breast cancer subtypes	49
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes	49
Correction: Anastasis: cell recovery mechanisms and potential role in cancer	48
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis	48
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer	48
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA	46
Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion	46
Correction: LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure	46
E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3Rα	46
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activatio	45
Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress	44
Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1	44
Correction: The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities	44
TGFβ1-induced hedgehog signaling suppresses the immune response of brain microvascular endothelial cells elicited by meningitic Escherichia coli	43
Castration promotes the browning of the prostate tumor microenvironment	43
RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter	42
Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts	41
Identification of biological pathways and processes regulated by NEK5 in breast epithelial cells via an integrated proteomic approach	41
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression	41
Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML	40
Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s disease	40
The roles of different microRNAs in the regulation of cholesterol in viral hepatitis	40
Communication between cells: exosomes as a delivery system in prostate cancer	39
NAT10 mediated ac4C acetylation driven m6A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma	39
Terphenyllin induces CASP3-dependent apoptosis and pyroptosis in A375 cells through upregulation of p53	39
Role of liver sinusoidal endothelial cell in metabolic dysfunction-associated fatty liver disease	38
The role of miR-155-5p in inflammation and mechanical loading during intervertebral disc degeneration	38
An update of Nrf2 activators and inhibitors in cancer prevention/promotion	38

GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma	37
Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice	37
The dynamic shifts of IL-10-producing Th17 and IL-17-producing Treg in health and disease: a crosstalk between ancient "Yin-Yang" theory and modern immunology	37
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways	36
Correction: Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis	36
Regulated cell death: discovery, features and implications for neurodegenerative diseases	35
Sirtuins in kidney diseases: potential mechanism and therapeutic targets	34
The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis	34
Neutrophil extracellular traps promote angiogenesis in gastric cancer	34
The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau	33
OTU deubiquitinase, ubiquitin aldehyde binding 2  (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (	33
Tumor-derived miR-6794-5p enhances cancer growth by promoting M2 macrophage polarization	33
Design of stable circular permutants of the GroEL chaperone apical domain	33
Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner	32
Extracellular vesicles in Helicobacter pylori-mediated diseases: mechanisms and therapeutic potential	31
Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing	31
Cellular and micro-environmental responses influencing the antitumor activity of all-trans retinoic acid in breast cancer	31
The significant role of amino acid metabolic reprogramming in cancer	31
Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1	31
Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction	31
The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion	30
Correction: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1	30
Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections	30
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo	30
Andrew H. Wyllie, a pioneer in the field of apoptosis	30
Trogocytosis in CAR immune cell therapy: a key mechanism of tumor immune escape	30
Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi3 heterotrimers	30
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A	29
Emerging roles and biomarker potential of WNT6 in human cancers	29
Acidic preconditioning induced intracellular acid adaptation to protect renal injury via dynamic phosphorylation of focal adhesion kinase-dependent activation of sodium hydrogen exchanger 1	29
Outcomes of physical exercises on initiation, progression, and treatment of breast cancer	29
Non-canonical non-genomic morphogen signaling in anucleate platelets: a critical determinant of prothrombotic function in circulation	29
PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes	29
Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)	29
N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis	29
Mechanisms underlying neutrophils adhesion to triple-negative breast cancer cells via CD11b-ICAM1 in promoting breast cancer progression	29
Exosome-transmitted HSPA9 facilitates bortezomib resistance by targeting TRIP13/USP1 signaling in multiple myeloma	28
Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development	28
Natural killer cells and their exosomes in viral infections and related therapeutic approaches: where are we?	28
cGAS-STING, inflammasomes and pyroptosis: an overview of crosstalk mechanism of activation and regulation	28
Mitochondrial dynamics and colorectal cancer biology: mechanisms and potential targets	28
Antizyme inhibitor family: biological and translational research implications	28
Distinct roles of centriole distal appendage proteins in ciliary assembly and disassembly	27
The role of KLRG1: a novel biomarker and new therapeutic target	27
Change in cytokine profiles released by mast cells mediated by lung cancer-derived exosome activation may contribute to cancer-associated coagulation disorders	27
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment	27
Cellular crosstalk in atherosclerotic plaque microenvironment	27
Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo	27
Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons	27
ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway	27
NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression	26
CRABP1-complexes in exosome secretion	26
Nuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling	26
Selective Pyk2 inhibition enhances bone restoration through SCARA5-mediated bone marrow remodeling in ovariectomized mice	26
Involvement of HDAC2-mediated kcnq2/kcnq3 genes transcription repression activated by EREG/EGFR-ERK-Runx1 signaling in bone cancer pain	26
The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling	26
The efferocytosis dilemma: how neutrophil extracellular traps and PI3K/Rac1 complicate diabetic wound healing	25
Upregulated FSP1 by GPD1/1L mediated lipid droplet accumulation enhances ferroptosis resistance and peritoneal metastasis in gastric cancer	25
Emerging roles of liquid-liquid phase separation in liver innate immunity	25
Co-culture engineering: a promising strategy for production of engineered extracellular vesicle for osteoarthritis treatment	25
Exercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling	25
Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling	25
Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism	25
Correction: Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	25
Novel energy optimizer, meldonium, rapidly restores acute hypobaric hypoxia-induced brain injury by targeting phosphoglycerate kinase 1	24
Unraveling the role of hypoxia-inducible factors in cutaneous melanoma: from mechanisms to therapeutic opportunities	24
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions	24
Photomodulation alleviates cellular senescence of aging adipose-derived stem cells	24
Targeting Endocytosis  and Cell Communications  in the Tumor Immune Microenvironment	24
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors	24
Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases	23
Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge	23
Programmed cell death disrupts inflammatory tumor microenvironment (TME) and promotes glioblastoma evolution	23
AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model	23
Correction: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome	23
Therapeutic targeting of the TPX2/TTK network in colorectal cancer	23
Reconstruction and analysis of a large-scale binary Ras-effector signaling network	23
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition	23
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape	22
Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A1	22

High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes	22
Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds	22
Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells	22
Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus	22
Mechanisms, combination therapy, and biomarkers in cancer immunotherapy resistance	22
Multiomics analysis revealed the mechanisms related to the enhancement of proliferation, metastasis and EGFR-TKI resistance in EGFR-mutant LUAD with ARID1A deficiency	22
c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment	22
Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors	21
Notch ankyrin domain: evolutionary rise of a thermodynamic sensor	21
Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species	21
Role of miRNAs interference on ovarian functions and premature ovarian failure	21
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner	21
Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors	21
ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer	21
Correction: SUMOylation-induced membrane localization of TRPV1 suppresses proliferation and migration in gastric cancer cells	21
Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC	21
Intratumoral microbiota in colorectal cancer: focus on specific distribution and potential mechanisms	21
CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner	21
Cerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment	20
(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota	20
The Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin	20
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope	20
Supplementation of spermidine enhances the quality of postovulatory aged porcine oocytes	20
IL-33-mediated activation of mast cells is involved in the progression of imiquimod-induced psoriasis-like dermatitis	20
NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis	20
R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells	20
ATP purinergic receptor signalling promotes Sca-1+ cell proliferation and migration for vascular remodelling	19
Extracellular vesicles from UTX-knockout endothelial cells boost neural stem cell differentiation in spinal cord injury	19
NEK8, a NIMA-family protein kinase at the core of the ciliary INV complex	19
The interaction of inflammasomes and gut microbiota: novel therapeutic insights	19
The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia	19
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease	19
Tumorigenic and tumoricidal properties of exosomes in cancers; a forward look	19
Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer	19
Helicobacter pylori promotes gastric intestinal metaplasia through activation of IRF3-mediated kynurenine pathway	19
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells	19
Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes	19
The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways	19
The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback	18
Mechanisms and functions of endocytosis in T cells	18
Interleukin-1 receptor antagonist inhibits metastatic potential by down-regulating CXCL12/CXCR4 signaling axis in colorectal cancer	18
Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases	18
Polyoxometalate inhibition of SOX2-mediated tamoxifen resistance in breast cancer	18
Correction: Hyoscyamus albus nortropane alkaloids reduce hyperglycemia and hyperinsulinemia induced in HepG2 cells through the regulation of SIRT1/NF-kB/JNK pathway	18
Disulfidptosis: a novel cell death modality induced by actin cytoskeleton collapse and a promising target for cancer therapeutics	18
Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities	18
Epigenetic modulation of the NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection	18
Coordinated regulation of immune contexture: crosstalk between STAT3 and immune cells during breast cancer progression	18
Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease	18
Co-targeting WIP1 and PARP induces synthetic lethality in hepatocellular carcinoma	18
1-Pyrroline-5-carboxylate inhibit T cell glycolysis in prostate cancer microenvironment by SHP1/PKM2/LDHB axis	18
Correction: Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2	18
Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts	18
ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy	18
Cellular signaling modulated by miRNA-3652 in ovarian cancer: unveiling mechanistic pathways for future therapeutic strategies	18
Modulating voltage-gated sodium channels to enhance differentiation and sensitize glioblastoma cells to chemotherapy	18
The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages	18
Pathophysiological role of calcium channels and transporters in the multiple myeloma	18
NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells	18
Ningetinib, a novel FLT3 inhibitor, overcomes secondary drug resistance in acute myeloid leukemia	18
Neutrophil extracellular traps induced by the hypoxic microenvironment in gastric cancer augment tumour growth	18
Neutrophil degranulation and myocardial infarction	18
The B56γ3-containing protein phosphatase 2A attenuates p70S6K-mediated negative feedback loop to enhance AKT-facilitated epithelial-mesenchymal transition in colorectal cancer	17
RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway	17
UHMK1-dependent phosphorylation of Cajal body protein coilin alters 5-FU sensitivity in colon cancer cells	17
HK2: a potential regulator of osteoarthritis via glycolytic and non-glycolytic pathways	17
ERK2-mediated phosphorylation of ZEB1 at S322 enhances PD-L1 expression and EMT, leading to pancreatic cancer progression	17
Protein disulfide isomerase plays a crucial role in mediating chemically-induced, glutathione depletion-associated hepatocyte injury in vitro and in vivo	17
BTN3A1 expressed in cervical cancer cells promotes Vγ9Vδ2 T cells exhaustion through upregulating transcription factors NR4A2/3 downstream of TCR signaling	17
Hyperglycemia-induced STING signaling activation leads to aortic endothelial injury in diabetes	17
Mitochondria-derived methylmalonic acid aggravates ischemia–reperfusion injury by activating reactive oxygen species-dependent ferroptosis	17
ER–mitochondria contact sites regulate hepatic lipogenesis via Ip3r-Grp75-Vdac complex recruiting Seipin	17
Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells	17
Lamprey immune protein triggers the ferroptosis pathway during zebrafish embryonic development	17
Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury	17
ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma	17
tRF-His-GTG-1 enhances NETs formation and interferon-α production in lupus by extracellular vesicle	17
Exosomes in skin photoaging: biological functions and therapeutic opportunity	16
Lanthanide conjugate Pr-MPO elicits anti-cancer activity by targeting lysosomal machinery and inducing zinc-dependent cataplerosis	16
ATXN3 promotes prostate cancer progression by stabilizing YAP	16
Targeting the hedgehog pathway in MET mutation cancers and its effects on cells associated with cancer development	16
Ubiquitin-specific protease: an emerging key player in cardiomyopathy	16
Intrinsically disordered proteins play diverse roles in cell signaling	16
Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer	16
Bcl-2 dependent modulation of Hippo pathway in cancer cells	16
TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors	16
Endothelial cell-derived extracellular vesicles modulate the therapeutic efficacy of mesenchymal stem cells through IDH2/TET pathway in ARDS	16
Deciphering the dynamics of methicillin-resistant Staphylococcus aureus biofilm formation: from molecular signaling to nanotherapeutic advances	16
COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches	16
Tobacco smoke condensate-induced senescence in endothelial cells was ameliorated by colchicine treatment via suppression of NF-κB and MAPKs P38 and ERK pathways activation	16
SUMOylation-induced membrane localization of TRPV1 suppresses proliferation and migration in gastric cancer cells	16
Histone variant H2AZ1 drives lung cancer progression through the RELA-HIF1A-EGFR signaling pathway	16
Insights into the diverse mechanisms and effects of variant CUL3-induced familial hyperkalemic hypertension	16
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner	16
Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis	15