Cell Communication and Signaling

Article	Citations
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor	567
Harnessing nanomedicine to target NF-κB signalling in cancer: at the intersection of inflammatory signalling, metabolic reprogramming, and therapeutic innovation	538
The scaffold protein AXIN1: gene ontology, signal network, and physiological function	349
The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity	337
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2	322
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage	313
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence	258
Caffeine mitigates ROS accumulation and attenuates motor neuron degeneration in the wobbler mouse model of amyotrophic lateral sclerosis	229
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer	226
Primary ciliogenesis is promoted during epithelial-mesenchymal transition via a miR-200 – DZIP1 axis	196
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression	190
Transmission Electron Microscopy-based characterization of Extracellular Vesicles from plasma and serum from Parkinson´s Disease patients	170
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling	155
Polydatin upregulates ZDHHC19 to promote apoptosis of acute myeloid leukemia cells via mediating BID palmitoylation	143
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment	143
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury	141
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases	138
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma	134
Proteomic analysis of hydrogen peroxide-treated human chondrocytes shows endoplasmic reticulum stress, cytoskeleton remodeling, and altered secretome composition	133
Mitochondrial dysfunction in the regulation of aging and aging-related diseases	132
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis	132
The role of lactate in cardiovascular diseases	127
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells	127
Chemotherapy reprograms miRNA expression profiles in apoptotic extracellular vesicles from medulloblastoma cells, regulating pro- and anti-proliferative effects on recipient drug-naïve cells	125
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases	114

Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis	113
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice	113
Catalase-deficient mice induce aging faster through lysosomal dysfunction	112
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation	109
Exosome RAB10 inhibits JAK1/STAT1 to hinder macrophage M1 polarization and promote tumor immune escape	104
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2	104
Epigenetic regulation of NR5A2 influences colorectal cancer cell stemness via a stemness-related transcription factor NANOG	99
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC	99
Interruption of cross-communication pathways alters the immune cell signature of pancreatic cancer and decreases tumor growth	97
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1	96
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	96
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology	96
Knockout of thyroid hormone receptor alpha a (thraa) enhances cardiac regeneration in zebrafish through metabolic and hypoxic regulation	93
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells	90
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish	89
Phase separation-mediated biomolecular condensates and their relationship to tumor	89
Tannic acid inhibits TNF-α signaling by targeting the protein disulfide isomerase and alleviates symptoms in an imiquimod-induced psoriasis mouse model	88
Chondroitin sulfate E activates IL-6/STAT3 signaling to drive androgen-independent growth in castration-resistant prostate cancer	87
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress	86
RT–ICI therapy induces a distal immunometabolic axis that shapes systemic macrophage polarization and enhances local T cell immunity	86
MSP-RON signaling in liver pathobiology and as an emerging therapeutic target: a review of the current evidence	85
Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation	83
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice	82
Epigenetic meets metabolism: novel vulnerabilities to fight cancer	82
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	79
New insights into the regulation of METTL3 and its role in tumors	77
Non-canonical STING activation by calcium influx paired to endoplasmic reticulum stress	77
Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell	76
MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis	76
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster	76
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis	75
Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells	74
Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s disease	72
RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter	72
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer	71
Role of DEAD/DEAH-box helicases in immunity, infection and cancers	70
Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice	69
NAT10 mediated ac4C acetylation driven m6A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma	69
HAX1 inhibits apoptosis and promotes maturation of neutrophils	69
SIRT6 cooperates with KDM5C to transcriptionally silence MICAL2 and inhibit tumorigenesis in pancreatic cancer	68
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA	68
Microglial depletion decreases Müller cell maturation and inner retinal vascular density	68
Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells	67
Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion	66
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways	65
Role of liver sinusoidal endothelial cell in metabolic dysfunction-associated fatty liver disease	65
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways	64
Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts	64
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activatio	63
Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress	61

Roles of Twist1 in lipid and glucose metabolism	61
TGFβ1-induced hedgehog signaling suppresses the immune response of brain microvascular endothelial cells elicited by meningitic Escherichia coli	60
Postbiotics as microbial-derived therapeutics for wound healing disorders: from molecular mechanisms to future application	60
A pro-carcinogenic oral microbe internalized by breast cancer cells promotes mammary tumorigenesis	60
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice	60
Correction: Anastasis: cell recovery mechanisms and potential role in cancer	59
Correction: LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure	59
Correction: The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities	59
O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology	58
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis	58
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone m	57
Castration promotes the browning of the prostate tumor microenvironment	56
Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML	56
E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3Rα	56
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction	56
Terphenyllin induces CASP3-dependent apoptosis and pyroptosis in A375 cells through upregulation of p53	56
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes	55
Correction: MMP-3 cleavage of Lamin A induces pro-migratory nuclear deformity, nucleophagy, and their autophagic secretion with extracellular vesicles in metastatic cancer	55
Dual inhibition of GTP-bound KRAS and mTOR in lung adenocarcinoma and squamous cell carcinoma harboring KRAS G12C	54
The primary cilium as a multifunctional organelle: emerging roles and unanswered questions	53
Opposing effects of Rho-associated coiled-coil kinase 1 (ROCK1) and ROCK2 in TGF-β-SMAD signaling	53
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis	53
STING-STAT1-ZBP1 axis orchestrates PANoptotic signaling in ischemia-reperfusion induced acute kidney injury	52
C-terminal tail of MAVS dictates organelle targeting and innate immune response	52
STING-ERO1 signaling exacerbates PARylation-mediated parthanatos in sepsis	50
Identification of biological pathways and processes regulated by NEK5 in breast epithelial cells via an integrated proteomic approach	50
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression	50
Organ-Specific Migration License (OSML) theory: a novel paradigm for spatiotemporal regulation and intervention of cross-organ immune cell migration in tumor immune responses	50
Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1	49
Functionalized exosomes for targeted therapy in cancer and regenerative medicine: genetic, chemical, and physical modifications	49
The critical role of necroptosis in oil cyst formation associated with autologous fat transplantation	49
An update of Nrf2 activators and inhibitors in cancer prevention/promotion	49
The roles of different microRNAs in the regulation of cholesterol in viral hepatitis	49
GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma	49
The role of miR-155-5p in inflammation and mechanical loading during intervertebral disc degeneration	49
The dynamic shifts of IL-10-producing Th17 and IL-17-producing Treg in health and disease: a crosstalk between ancient "Yin-Yang" theory and modern immunology	48
IL-23 promotes neuronal ferroptosis via IL-23R/STAT3 signaling after traumatic brain injury	48
Nanobodies and their derivatives: pioneering the future of cancer immunotherapy	48
Andrew H. Wyllie, a pioneer in the field of apoptosis	47
Retinal pigment epithelium-derived extracellular vesicles mediate outer blood retinal barrier disruption in response to AMD-related stress	47
Cancer-associated adipocytes promote peritoneal metastasis of colorectal signet ring cell carcinoma via FABP4 induction	47
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo	47
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A	47
Correction: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1	46
Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)	46
Metformin attenuates HSV-1-induced neuropathic pain by restoring Sirt3-mediated mitophagy	46
Mitochondria and the epigenome: maternal co-inheritance and crosstalk from oocyte to embryo	46
OTU deubiquitinase, ubiquitin aldehyde binding 2  (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (	46
The neuro-vascular-immune triad: the interactive network in the tumor microenvironment	46
Targeting of specific CCR5-G protein complexes underlies biased signaling by HIV-1 envelope glycoproteins	45
Correction: Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis	45
The cellular economy while crafting regulatory processes relies on protein intrinsic disorder: how and why precision comes at a cost in protein structure	44
Sirtuins in kidney diseases: potential mechanism and therapeutic targets	44
Targeting endolysosomal acidification inhibits poxvirus entry and replication	44
Non-canonical non-genomic morphogen signaling in anucleate platelets: a critical determinant of prothrombotic function in circulation	44
The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion	43
Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi3 heterotrimers	43
Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1	42
Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development	42
Exosome-transmitted HSPA9 facilitates bortezomib resistance by targeting TRIP13/USP1 signaling in multiple myeloma	42
Cellular and micro-environmental responses influencing the antitumor activity of all-trans retinoic acid in breast cancer	42
PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes	42
Design of stable circular permutants of the GroEL chaperone apical domain	41
Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts	41
Combination therapy strategies in engineered 177Lu radiopharmaceuticals beyond single modality: design principles and application outlet	41
Outcomes of physical exercises on initiation, progression, and treatment of breast cancer	41
Acidic preconditioning induced intracellular acid adaptation to protect renal injury via dynamic phosphorylation of focal adhesion kinase-dependent activation of sodium hydrogen exchanger 1	41
N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis	41
cGAS-STING, inflammasomes and pyroptosis: an overview of crosstalk mechanism of activation and regulation	41
Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections	41
Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner	41
Celecoxib inhibits COX-2 and initiates YAP-dependent mitochondrial apoptosis via YBX1 shuttling in hepatocellular carcinoma	41
Tumor-derived miR-6794-5p enhances cancer growth by promoting M2 macrophage polarization	41
Cellular crosstalk in atherosclerotic plaque microenvironment	40
Lactate shuttle between cytotrophoblast and syncytiotrophoblast in the placenta enhances ferroptosis resistance and maintains placental homeostasis: implications for early pregnancy loss	40
NOTCH3 Mutations in CADASIL: a multicellular perspective on neurodegeneration	40
Trogocytosis in CAR immune cell therapy: a key mechanism of tumor immune escape	40
Mechanisms underlying neutrophils adhesion to triple-negative breast cancer cells via CD11b-ICAM1 in promoting breast cancer progression	40
Extracellular vesicles in Helicobacter pylori-mediated diseases: mechanisms and therapeutic potential	40
The role of KLRG1: a novel biomarker and new therapeutic target	40

Emerging roles and biomarker potential of WNT6 in human cancers	39
Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction	39
Neutrophil extracellular traps promote angiogenesis in gastric cancer	39
Mitochondrial dynamics and colorectal cancer biology: mechanisms and potential targets	39
Antizyme inhibitor family: biological and translational research implications	39
Natural killer cells and their exosomes in viral infections and related therapeutic approaches: where are we?	39
Glycosylation as an intricate post-translational modification process takes part in glycoproteins related immunity	38
Whole-gene CRISPR/cas9 library screen revealed targeting STAT6 increased the sensitivity of liver cancer to celecoxib via inhibiting arachidonic acid shunting	38
P2X7 is an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells	38
Campylobacter jejuni regulates cell cycle progression to potentiate host cell invasion	38
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment	38
Distinct roles of centriole distal appendage proteins in ciliary assembly and disassembly	38
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors	38
The significant role of amino acid metabolic reprogramming in cancer	38
eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling	38
Programmed cell death disrupts inflammatory tumor microenvironment (TME) and promotes glioblastoma evolution	38
Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge	38
IL-15 promotes immune escape, invasion, and metastasis of pancreatic cancer by upregulating PD-L1 expression via the JAK1/STAT1/IRF1 pathway	37
Mitochondria-derived vesicles serve as reactors in response to stress in cardiomyocytes	37
From cell lines to the clinic: identifying a urinary BlCa-EV signature through comparative proteomics of bladder cancer lysates and extracellular vesicles	37
Correction: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome	37
Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells	37
Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo	37
Co-culture engineering: a promising strategy for production of engineered extracellular vesicle for osteoarthritis treatment	37
The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling	37
Exercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling	37
Neutrophil extracellular traps released by CD177+ neutrophils aggravated inflammation and neuronal impairment post-SCI	37
Plasma circulating extracellular vesicles reveal dysregulation of synaptic signaling in SHIV-infected rhesus macaque	37
A novel extracellular flux assay workflow uncovers impaired sciatic nerve mitochondrial respiration in diabetic db/db mice	36
Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus	36
Photomodulation alleviates cellular senescence of aging adipose-derived stem cells	36
SRY mediates male-specific susceptibility to acute liver injury	36
Correction: Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	36
Involvement of HDAC2-mediated kcnq2/kcnq3 genes transcription repression activated by EREG/EGFR-ERK-Runx1 signaling in bone cancer pain	36
Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A1	36
Upregulated FSP1 by GPD1/1L mediated lipid droplet accumulation enhances ferroptosis resistance and peritoneal metastasis in gastric cancer	36
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition	35
Mitochondrial homeostasis meets novel programmed cell death: crosstalk mechanisms underlying cardiovascular diseases progression	35
Targeting Endocytosis  and Cell Communications  in the Tumor Immune Microenvironment	35
Emerging roles of liquid-liquid phase separation in liver innate immunity	35
Novel energy optimizer, meldonium, rapidly restores acute hypobaric hypoxia-induced brain injury by targeting phosphoglycerate kinase 1	35
An attempt to explain what intrinsically disordered TCF4 does in its spare time when PTHS-related mutations prevent it from doing its job	35
Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling	35
Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells	35
Nuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling	34
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions	34
NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression	34
Selective Pyk2 inhibition enhances bone restoration through SCARA5-mediated bone marrow remodeling in ovariectomized mice	34
Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds	34
Multiomics analysis revealed the mechanisms related to the enhancement of proliferation, metastasis and EGFR-TKI resistance in EGFR-mutant LUAD with ARID1A deficiency	34
The cancer-associated fibroblast facilitates YAP liquid-liquid phase separation to promote cancer cell stemness in HCC	34
AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model	34
Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases	33
Change in cytokine profiles released by mast cells mediated by lung cancer-derived exosome activation may contribute to cancer-associated coagulation disorders	33
Unraveling the role of hypoxia-inducible factors in cutaneous melanoma: from mechanisms to therapeutic opportunities	33
Therapeutic targeting of the TPX2/TTK network in colorectal cancer	33
c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment	33
The efferocytosis dilemma: how neutrophil extracellular traps and PI3K/Rac1 complicate diabetic wound healing	33
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape	33
Cytoplasmic retention of IRF3 binding Vimentin competitively with ERK1/2 mitigates acute myeloid leukemia through TFEB nuclear translocation	33
Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism	33
The heterogeneity of monocyte-derived macrophages in MASH pathogenesis	33
Mechanisms, combination therapy, and biomarkers in cancer immunotherapy resistance	33
CRABP1-complexes in exosome secretion	33
IL-33-mediated activation of mast cells is involved in the progression of imiquimod-induced psoriasis-like dermatitis	32
Fusobacterium nucleatum-reprogrammed adipocytes promote tumor cisplatin resistance through the CCL2-CCR2 axis in the necrotic metastatic neck nodes of head and neck carcinoma	32
Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species	32
Progress on multifunctional transmembrane protein ATG9A	32
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells	31
Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors	31
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease	31
An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection	31
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner	30
Neutrophil extracellular traps induced by the hypoxic microenvironment in gastric cancer augment tumour growth	30
The interaction of inflammasomes and gut microbiota: novel therapeutic insights	30
The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection	30
Off-target engagement of sotorasib with PPARγ via FABP4: a novel mechanism driving interstitial lung disease	30
Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts	30
ATP purinergic receptor signalling promotes Sca-1+ cell proliferation and migration for vascular remodelling	30
The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways	30
RNF20/RNF40 supports the aggressive behavior in cervical cancer by regulating a peroxisome-based anti-ferroptotic mechanism	30
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms	30
Extracellular vesicles from UTX-knockout endothelial cells boost neural stem cell differentiation in spinal cord injury	30
(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota	30
High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes	30
Evidence for a JAK2/STAT3 proinflammatory and vasculogenic mimicry interrelated molecular signature in adipocyte-derived mesenchymal stromal/stem cells	30
Advanced nanotechnology in enhancing immune checkpoint inhibitors (ICIs) for head and neck cancer therapy	29
Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC	29
Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer	29
Notch ankyrin domain: evolutionary rise of a thermodynamic sensor	29
Cerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment	29
Cellular signaling modulated by miRNA-3652 in ovarian cancer: unveiling mechanistic pathways for future therapeutic strategies	29
The scaffold protein DLG4 facilitates RNF63-mediated ubiquitination and degradation of STAT3 in non-small cell lung cancer	29
Post-traumatic stress disorder impairs CD8+ T cell-dependent anti-tumor immune responses by downregulating thiamine	29
Immunosuppressants rewire the gut microbiome-alloimmune axis through time-dependent and tissue-specific mechanisms	29