OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Communication and Signaling is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC	343
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells	268
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress	261
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor	198
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish	174
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2	153
Epigenetic meets metabolism: novel vulnerabilities to fight cancer	152
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling	152
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice	136
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	127
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2	125
Phase separation-mediated biomolecular condensates and their relationship to tumor	114
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma	105
Catalase-deficient mice induce aging faster through lysosomal dysfunction	105
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types	102
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer	98
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases	93
The scaffold protein AXIN1: gene ontology, signal network, and physiological function	86
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation	82
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury	77
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression	77
Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response	77
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1	75
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence	74
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage	71

Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases	70
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells	70
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology	68
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	67
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis	66
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice	63
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis	63
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment	62
The role of lactate in cardiovascular diseases	60
New insights into the regulation of METTL3 and its role in tumors	58
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction	57
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster	57
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice	55
Microglial depletion decreases Müller cell maturation and inner retinal vascular density	54
O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology	53
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways	52
MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis	52
Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells	51
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone m	50
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis	50
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis	49
Roles of Twist1 in lipid and glucose metabolism	49
Patient-derived scaffolds influence secretion profiles in cancer cells mirroring clinical features and breast cancer subtypes	49
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes	49