OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Communication and Signaling is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC	414
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells	311
Epigenetic meets metabolism: novel vulnerabilities to fight cancer	289
Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response	225
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish	200
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor	190
Proteomic analysis of hydrogen peroxide-treated human chondrocytes shows endoplasmic reticulum stress, cytoskeleton remodeling, and altered secretome composition	181
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases	179
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice	164
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2	151
Chemotherapy reprograms miRNA expression profiles in apoptotic extracellular vesicles from medulloblastoma cells, regulating pro- and anti-proliferative effects on recipient drug-naïve cells	144
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage	129
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury	127
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence	126
Catalase-deficient mice induce aging faster through lysosomal dysfunction	112
Knockout of thyroid hormone receptor alpha a (thraa) enhances cardiac regeneration in zebrafish through metabolic and hypoxic regulation	108
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells	99
Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation	97
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types	96
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress	96
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis	93
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2	90
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment	89
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	86
New insights into the regulation of METTL3 and its role in tumors	84

The role of lactate in cardiovascular diseases	83
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling	82
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology	81
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis	80
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1	80
Mitochondrial dysfunction in the regulation of aging and aging-related diseases	75
Phase separation-mediated biomolecular condensates and their relationship to tumor	75
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer	71
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation	69
MSP-RON signaling in liver pathobiology and as an emerging therapeutic target: a review of the current evidence	66
The scaffold protein AXIN1: gene ontology, signal network, and physiological function	65
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression	64
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	62
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma	62
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster	60
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases	60
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice	60
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction	59
IL-23 promotes neuronal ferroptosis via IL-23R/STAT3 signaling after traumatic brain injury	58
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice	58
Communication between cells: exosomes as a delivery system in prostate cancer	58
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis	57
Correction: Anastasis: cell recovery mechanisms and potential role in cancer	57
GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma	57
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes	56
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activatio	55
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis	55
Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice	53