OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Communication and Signaling is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The exosome journey: from biogenesis to uptake and intracellular signalling	806
A review on exosomes application in clinical trials: perspective, questions, and challenges	230
Types of nuclear localization signals and mechanisms of protein import into the nucleus	207
Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons	164
Drug resistance and Cancer stem cells	158
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	105
How vascular smooth muscle cell phenotype switching contributes to vascular disease	102
Extracellular vesicles: mediators of intercellular communication in tissue injury and disease	95
Regulatory role of short-chain fatty acids in inflammatory bowel disease	91
Intrinsically disordered proteins play diverse roles in cell signaling	88
Cancer combination therapies by angiogenesis inhibitors; a comprehensive review	88
A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication	82
The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems	79
Short-chain fatty acids in diseases	77
Reprogramming of glutamine metabolism and its impact on immune response in the tumor microenvironment	74
Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition	73
The biology of tardigrade disordered proteins in extreme stress tolerance	71
An update of Nrf2 activators and inhibitors in cancer prevention/promotion	66
On the roles of intrinsically disordered proteins and regions in cell communication and signaling	66
Eukaryotic translation initiation factors as promising targets in cancer therapy	66
Role of oxidative stress and inflammation-related signaling pathways in doxorubicin-induced cardiomyopathy	57
Regulated cell death: discovery, features and implications for neurodegenerative diseases	55
The role of mitophagy in innate immune responses triggered by mitochondrial stress	53
Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway	53
Scavenger receptors in host defense: from functional aspects to mode of action	52

Cancer-derived exosomal miR-7641 promotes breast cancer progression and metastasis	51
Tumor-associated macrophages promote epithelial–mesenchymal transition and the cancer stem cell properties in triple-negative breast cancer through CCL2/AKT/β-catenin signaling	51
The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases	48
The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets	47
Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism	47
Long-term differentiating primary human airway epithelial cell cultures: how far are we?	45
The emerging role of the KCTD proteins in cancer	44
Circadian clock: a regulator of the immunity in cancer	43
Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development	43
Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation	42
ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway	42
Intrinsic disorder is an essential characteristic of components in the conserved circadian circuit	42
Role of autophagy on cancer immune escape	40
PI3K/AKT signaling pathway as a critical regulator of epithelial-mesenchymal transition in colorectal tumor cells	40
Interplay of oxidative stress, cellular communication and signaling pathways in cancer	39
c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment	39