OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Communication and Signaling is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)

Article	Citations
The exosome journey: from biogenesis to uptake and intracellular signalling	691
A review on exosomes application in clinical trials: perspective, questions, and challenges	185
Types of nuclear localization signals and mechanisms of protein import into the nucleus	175
Drug resistance and Cancer stem cells	136
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma	132
Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons	127
A code within the genetic code: codon usage regulates co-translational protein folding	121
TGF-β and WNT signaling pathways in cardiac fibrosis: non-coding RNAs come into focus	103
Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages	103
The crosstalk: exosomes and lipid metabolism	99
Calcineurin	87
Extracellular vesicles: mediators of intercellular communication in tissue injury and disease	87
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	86
Intrinsically disordered proteins play diverse roles in cell signaling	78
Cancer combination therapies by angiogenesis inhibitors; a comprehensive review	74
How vascular smooth muscle cell phenotype switching contributes to vascular disease	73
Regulatory role of short-chain fatty acids in inflammatory bowel disease	68
Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition	67
Role of exosomes in malignant glioma: microRNAs and proteins in pathogenesis and diagnosis	66
The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems	66
The biology of tardigrade disordered proteins in extreme stress tolerance	65
The deubiquitinase USP22 regulates PD-L1 degradation in human cancer cells	62
Reprogramming of glutamine metabolism and its impact on immune response in the tumor microenvironment	60
The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect	60
Eukaryotic translation initiation factors as promising targets in cancer therapy	58

On the roles of intrinsically disordered proteins and regions in cell communication and signaling	58
Intestinal microbiota: a new force in cancer immunotherapy	57
Mitochondrial DNA drives noncanonical inflammation activation via cGAS–STING signaling pathway in retinal microvascular endothelial cells	57
A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication	52
YYFZBJS ameliorates colorectal cancer progression in ApcMin/+ mice by remodeling gut microbiota and inhibiting regulatory T-cell generation	51
Regulated cell death: discovery, features and implications for neurodegenerative diseases	51
The role of mitophagy in innate immune responses triggered by mitochondrial stress	51
An update of Nrf2 activators and inhibitors in cancer prevention/promotion	49
Cancer-derived exosomal miR-7641 promotes breast cancer progression and metastasis	48
Role of extracellular vesicles in tumour microenvironment	45
Scavenger receptors in host defense: from functional aspects to mode of action	44
Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles	42
Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway	42
Short-chain fatty acids in diseases	42
Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism	42
The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases	42
Circadian clock: a regulator of the immunity in cancer	42