Journal of Nanobiotechnology

Article	Citations
Double-layered N-S1 protein nanoparticle immunization elicits robust cellular immune and broad antibody responses against SARS-CoV-2	289
Self-disassembling diatomic nanocluster bomb unlock reciprocal synergistic multi-pathway cancer therapy	279
Multifunctional nanoagonist enhances photodynamic therapy-driven in situ cancer vaccination by inhibiting tumor thrombosis	265
Fusiform nanoparticle boosts efficient genetic transformation in Sclerotinia sclerotiorum	252
Hyaluronic acid-functionalized supramolecular nanophotosensitizers for targeted photoimmunotherapy of triple-negative breast cancer	250
Correction: Bacterial outer membrane vesicle-cancer cell hybrid membrane-coated nanoparticles for sonodynamic therapy in the treatment of breast cancer bone metastasis	244
Correction: Conductive single-wall carbon nanotubes/extracellular matrix hybrid hydrogels promote the lineage-specific development of seeding cells for tissue repair through reconstructing an integrin	236
Design and mechanistic insights into ZMF59/CpG: a complementary adjuvant system boosting immunity and safety in herpes zoster vaccines	227
H2S-responsive CuSe nanoparticles convert into CuSSe in situ with band gap modulation for oxygen self-supply and enhanced colon cancer phototherapy	223
MnO2 and roflumilast-loaded probiotic membrane vesicles mitigate experimental colitis by synergistically augmenting cAMP in macrophage	218
Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II	211
Multifunctional nanoagent for enhanced cancer radioimmunotherapy via pyroptosis and cGAS-STING activation	210
Structural optimization of Sr/Zn-phosphate conversion coatings triggered by ions preloading on micro/nanostructured titanium surfaces for bacterial infection control and enhanced osteogenesis	202
Engineering BiTE-inspired IPSC-exosomes to potentiate CAR-T cell therapy against lung cancer	199
Multifunctional copper-based nanoparticles potentiate colorectal cancer immunotherapy via synergistic metabolic remodeling and cGAS-STING pathway activation	176
Maternal exposure to fullerenols impairs placental development in mice by inhibiting estriol synthesis and reducing ERα	172
Green synthesis of glyco-CuInS2 QDs with visible/NIR dual emission for 3D multicellular tumor spheroid and in vivo imaging	172
Assembling Au8 clusters on surfaces of bifunctional nanoimmunomodulators for synergistically enhanced low dose radiotherapy of metastatic tumor	171
A clinically feasible circulating tumor cell sorting system for monitoring the progression of advanced hepatocellular carcinoma	169
Pathogen-microenvironment-responsive and antioxidant-buffered propiconazole nanofungicide for safe and effective fungal disease control	167
Tumor-activated dual metabolic nanomodulator turns over tolerogenic tumor control and unleashes systemic immune responses	166
Exosomes from umbilical cord-derived mesenchymal stem cells combined with gelatin methacryloyl inhibit vein graft restenosis by enhancing endothelial functions	163
Neutrophil-guided pro-efferocytic mRNA platform for accelerated diabetic wound repair	161
Immune-modified exosome vaccine loaded with liver cancer epitope peptides induces potent and specific antitumor immunity	159
DNAzyme hydrogels specifically inhibit the NLRP3 pathway to prevent radiation-induced skin injury in mice	159

Gold-nanosphere mitigates osteoporosis through regulating TMAO metabolism in a gut microbiota-dependent manner	158
Inorganic nanoparticle-based treatment approaches for colorectal cancer: recent advancements and challenges	158
Curcumin-loaded copper/iron bimetallic nanoparticle-incorporated hydrogel scaffold: a sequential microenvironment reprogramming platform for accelerated chronic wound healing	155
A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury	147
Cartilage targeting therapy with reactive oxygen species-responsive nanocarrier for osteoarthritis	147
Microneedle delivery system with rapid dissolution and sustained release of bleomycin for the treatment of hemangiomas	145
BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma	145
High-throughput synthesis and optimization of ionizable lipids through A3 coupling for efficient mRNA delivery	137
Integrated triple signal amplification strategy for ultrasensitive electrochemical detection of gastric cancer-related microRNA utilizing MoS2-based nanozyme, hybridization chain reaction, and horsera	137
Targeting CAD with a tumor microenvironment-responsive nano-heterojunction for synergistic induction of cuproptosis and inhibition of colorectal cancer progression	136
Recent progress of non-linear topological structure polymers: synthesis, and gene delivery	130
MXene-based nanosheet for enhanced glioma therapy via photonic hyperthermia to boost the abscopal effect of radioimmunotherapy	129
Oxygen vacancy-engineered bimetallic nanozymes for disrupting electron transport chain and synergistic multi-enzyme activity to reverse oxaliplatin resistance in colorectal cancer	128
Mesoporous multimetallic PdPtBi nanozymes target redox imbalance and glutamine deprivation for immuno-chemodynamic therapy	128
Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome	127
Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity	124
A sequentially targeted and pathology-responsive nanoplatform for synergistic treatment of dry eye disease via concurrent anti-inflammation and mitochondrial ROS scavenging	124
Dephosphorylation-regulated MNAzyme-PER cascade as a programmable converter for multi-task molecular actuation	122
Apoptotic extracellular vesicles act as master regulators of the bone healing niche	121
An ESIPT-AIE nanosensor for ONOO− imaging: decoding heavy metal stress and ferroptosis in living plants	119
The nucleic acid reactions on the nanomaterials surface for biomedicine	119
Piezoelectric heterojunction/polyetherketoneketone composite with enhanced sonodynamic efficacy and nanozyme activities for anti-infection and encouraging neurovascular ossification	118
Biomimetic β-lapachone and hemin nanoassembly for intracellular oxidation cascade amplified ferroptosis in hepatocellular carcinoma therapy	117
Nanotechnology for research and treatment of the intestine	117
A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression	117
An oxygen-generating nanoplatform remodels the immunosuppressive tumor microenvironment via synergistic lactate depletion and sonodynamic therapy	116
Co-delivery of axitinib and PD-L1 siRNA for the synergism of vascular normalization and immune checkpoint inhibition to boost anticancer immunity	115
Nanoplastics-mediated physiologic and genomic responses in pathogenic Escherichia coli O157:H7	115
An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironments	113
Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles	112
De novo strategy of organic semiconducting polymer brushes for NIR-II light-triggered carbon monoxide release to boost deep-tissue cancer phototheranostics	111
Radionuclide-labeled oxygen-self-supplying calcium reservoir for high-efficiency radioimmunotherapy via synergistic pyroptosis activation and PD-L1 downregulation	110
Dual-function TA@CaCO3 nanomedicine targeting M2 macrophage lipid peroxidation sensitivity in rheumatoid arthritis therapy	109
αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma	106
Transdermal delivery of CRISPR/Cas9-mediated melanoma gene therapy via polyamines-modified thermosensitive hydrogels	105
Exosomes: compositions, biogenesis, and mechanisms in diabetic wound healing	105
Harnessing protein sensing ability of electrochemical biosensors via a controlled peptide receptor–electrode interface	104
Nanomedicine's shining armor: understanding and leveraging the metal-phenolic networks	104
Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications	103
A high-affinity CEA-targeted nanobody for 68Ga PET imaging and 177Lu-based radioisotope therapy: preclinical and first-in-human evaluation	103
Customizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy	100
An encounter between metal ions and natural products: natural products-coordinated metal ions for the diagnosis and treatment of tumors	100
Engineered extracellular vesicles-mediated curcumin delivery in brain microenvironment modulating lysosomes, mitochondria, and microglia reprogram for parkinson’s disease therapy	100
Design of a new electrochemical aptasensor based on screen printed carbon electrode modified with gold nanoparticles for the detection of fumonisin B1 in maize flour	99
Self-activated prodrug nanocomposites reprogramming lactic acid metabolism to initiate acidosis-endoplasmic reticulum stress cascade and potentiate immunogenic cell death for enhanced liver cancer the	97
Oral administration of Sophora Flavescens-derived exosomes-like nanovesicles carrying CX5461 ameliorates DSS-induced colitis in mice	96
3D printed shape-memory piezoelectric scaffolds with in-situ self-power properties for bone defect repair	95
New anti-cancer explorations based on metal ions	95
Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizospher	94
The current status of stimuli-responsive nanotechnologies on orthopedic titanium implant surfaces	93

Gouqi-derived nanovesicles (GqDNVs) inhibited dexamethasone-induced muscle atrophy associating with AMPK/SIRT1/PGC1α signaling pathway	93
Biocompatible exosome-modified fibrin gel accelerates the recovery of spinal cord injury by VGF-mediated oligodendrogenesis	93
Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization	92
Macrophage membrane (MMs) camouflaged near-infrared (NIR) responsive bone defect area targeting nanocarrier delivery system (BTNDS) for rapid repair: promoting osteogenesis via phototherapy and modula	92
CPA-Cas12a-based lateral flow strip for portable assay of Methicillin-resistant Staphylococcus aureus in clinical sample	91
Protective effect of spore oil-functionalized nano-selenium system on cisplatin-induced nephrotoxicity by regulating oxidative stress-mediated pathways and activating immune response	91
Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis	91
PDGFR-α shRNA-polyplex for uveal melanoma treatment via EMT mediated vasculogenic mimicry interfering	90
Intestinal nanoparticle delivery and cellular response: a review of the bidirectional nanoparticle-cell interplay in mucosa based on physiochemical properties	90
Lipid liquid-crystalline nanoparticles as a suitable platform for accommodating sensitive membrane proteins: monitoring the activity of HMG-CoA reductase	89
NK-92 cells labeled with Fe3O4-PEG-CD56/Avastin@Ce6 nanoprobes for the targeted treatment and noninvasive therapeutic evaluation of breast cancer	89
Correction: Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration	89
Expression of Concern: Curcumin- and resveratrol-co-loaded nanoparticles in synergistic treatment of hepatocellular carcinoma	88
CT-sensitized nanoprobe for effective early diagnosis and treatment of pulmonary fibrosis	88
Targeting phosphatidylserine in tumor cell membranes with a zinc-containing molecule to efficiently combat tumor metastasis	88
Visualizing cancer resistance via nano-quenching and recovery detector of CD44	88
Polystyrene nanoplastics induce hepatic steatosis by disrupting autophagic degradation of NCoR1 and suppressing PPARα-mediated fatty acid oxidation	88
Modulating metal-organic frameworks by surface engineering of stearic acid modification for follicular drug delivery and enhanced hair growth promotion	88
Carbon-based quantum dots enhance platelets aggregation through migrasomes biogenesis	87
Protection of zero-valent iron nanoparticles against sepsis and septic heart failure	86
Deep learning-driven morphological fingerprinting: rapid, accurate and low-cost pathogen identification via the analysis of dried patterns of droplets	86
Stiffness-dependent CMOT hydrogels promote mucosal repair in ulcerative colitis through YAP‑mediated mechanosensing in intestinal epithelial cells	85
Stimuli-responsive smart materials enabled high-performance biosensors for liquid biopsies	85
Cycloastragalol nanoparticle-loaded composite hydrogel as an injectable embolic agent for vascular repair in a mouse model of abdominal aortic aneurysm	84
Therapeutic strategies for ischemic heart disease with natural product-based nanomedicines	83
Robust generation of distal respiratory airway organoids by an engineered cuboid chip	83
Dual antibody-aided mesoporous nanoreactor for H2O2 self-supplying chemodynamic therapy and checkpoint blockade immunotherapy in triple-negative breast cancer	83
Poria cocos-derived exosome-like nanoparticles ameliorate lymphedema by reprogramming fibroblast metabolism via enhanced TCA cycle flux	82
Sonodynamic and sonomechanical effect on cellular stemness and extracellular physicochemical environment to potentiate chemotherapy	80
Correction: SIRT5-modified human umbilical cord mesenchymal stem cells loaded with antioxidant polydopamine nanozyme enhance parpi resistance in ovarian cancer via fatty acid metabolism reprogramming	79
Self-assembled transdermal nanogels control scar formation by inhibiting fibroblast proliferation and fibrosis with glycolysis regulation via the PI3K/Akt/mTOR pathway	79
Polypyrrole-ferric phosphate-methotrexate nanoparticles enhance apoptosis/ferroptosis of M1 macrophages via autophagy blockage for rheumatoid arthritis treatment	79
DNA-based molecular classifiers for the profiling of gene expression signatures	78
The development of a novel zeolite-based assay for efficient and deep plasma proteomic profiling	78
Polyurethane-based nanofibrous mat containing porphyrin with photosensitivity and bactericidal properties can promote cutaneous tissue healing in rats	78
Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles	77
Tumor-specific enhanced NIR-II photoacoustic imaging via photothermal and low-pH coactivated AuNR@PNIPAM-VAA nanogel	77
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia	77
Exosomes derived from platelet-rich plasma alleviate synovial inflammation by enhancing synovial lymphatic function	77
Crosslinked-hybrid nanoparticle embedded in thermogel for sustained co-delivery to inner ear	76
Delivery of an ERK inhibitor using bioactive lipid nanoparticles reduces angiogenesis and prevents oral squamous cell carcinoma development	76
Alternating magnetic field-responsive engineered probiotics for anxiety therapy via gut-brain axis modulation	76
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer	76
Dendritic mesoporous silica-delivered siRNAs nano insecticides to prevent Sogatella furcifera by inhibiting metabolic detoxification and reproduction	75
ROS-mitochondria-NLRP3/STING axis mediates the enhanced anti-coronavirus activity of ZIF8 nanoparticles	75
A bivalent spike-targeting nanobody with anti-sarbecovirus activity	75
Effective delivery of miR-150-5p with nucleus pulposus cell-specific nanoparticles attenuates intervertebral disc degeneration	75
Multiplexed evaluation of immunity against SARS-CoV-2 variants using surface enhanced fluorescence from a nanostructured plasmonic chip	75
Mesoporous silica nanoparticle-encapsulated Bifidobacterium attenuates brain Aβ burden and improves olfactory dysfunction of APP/PS1 mice by nasal delivery	74
Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges	74
Photocurable hydrogel containing MOF nanoenzymes for comprehensive pulpitis treatment: antibacterial, anti-inflammatory, and osteogenic actions	74
Simple-synthesis VO₂ nanoparticles as robust nanozymes for synergistic antibacterial therapy and abscess repair	73
Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence	73
Multifunctional nanoplatform with near-infrared triggered nitric-oxide release for enhanced tumor ferroptosis	73
Honeycomb-inspired porous biomimetic scaffold with specific adaptability to host cells behavior for bone repair	73
Electro-controlled assembled of biphasic guided bone regeneration membrane for healing of diabetic periodontal bone defects	73
Dual-responsive polypyridyl Ru(II)-scaffolded hydrogel for trinitarian tumor therapy activated by mono-wavelength photo-irradiation	73
Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update	72
NIR-responsive Cu2 − xSe@Fc nanoparticles for photothermal- ferroptosis combination therapy in esophageal cancer	72
Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications	72
Turning gray selenium and sublimed sulfur into a nanocomposite to accelerate tissue regeneration by isothermal recrystallization	72
Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy	71
Highly hydrophilic and dispersed TiO2 nano-system with enhanced photocatalytic antibacterial activities and accelerated tissue regeneration under visible light	71
Future embracing: exosomes driving a revolutionary approach to the diagnosis and treatment of idiopathic membranous nephropathy	71
Enhanced multienzyme catalytic activity of Mn MOF induced by bioligands for efficient tumor therapy	71
Biomimetic PD-1 macrophage nanoplatform for Cip2a silencing and immune activation in oral squamous cell carcinoma	71
Yin-Yang: two sides of extracellular vesicles in inflammatory diseases	71
Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production	71
Circ_0001947 encapsulated by small extracellular vesicles promotes gastric cancer progression and anti-PD-1 resistance by modulating CD8+ T cell exhaustion	71
Exosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy	71
Unraveling the structure-activity relationship of alloying in nanozyme design for synergistic tumor metabolic-immunotherapy	70
Molybdesum selenide-based platelet-rich plasma containing carboxymethyl chitosan/polyvinyl pyrrolidone composite antioxidant hydrogels dressing promotes the wound healing	69
Croconaine-based NIR-II fluorescence imaging-guided tumor photothermal therapy induces long-term antitumor immune memory	69
Highly integrated, self-powered and activatable bipedal DNA nanowalker for imaging of base excision repair in living cells	69
Antibacterial metal nanoclusters	69
Electrical aligned polyurethane nerve guidance conduit modulates macrophage polarization and facilitates immunoregulatory peripheral nerve regeneration	69
Biomimetic calcium carbonate nanoparticles delivered IL-12 mRNA for targeted glioblastoma sono-immunotherapy by ultrasound-induced necroptosis	69
hUC-MSC-exosomes deliver Let-7b/7f-5p to dermal papilla cells for a multi-target synergistic treatment of androgenetic alopecia	68
Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation	68
MXene-integrated microneedles reprogram diabetic-associated macrophages for deep-wound infection therapy and immunoprotection	68

Radiodynamic therapy with CsI(na)@MgO nanoparticles and 5-aminolevulinic acid	68
Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion	68
Photodynamic and nitric oxide therapy-based synergistic antimicrobial nanoplatform: an advanced root canal irrigation system for endodontic bacterial infections	67
Emerging nano-immunotherapeutic strategies achieve metastatic colorectal cancer precision therapy	67
Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges	67
Enzymatically responsive nanocarriers targeting PD-1 and TGF-β pathways reverse immunotherapeutic resistance and elicit robust therapeutic efficacy	66
A novel spherical GelMA-HAMA hydrogel encapsulating APET×2 polypeptide and CFIm25-targeting sgRNA for immune microenvironment modulation and nucleus pulposus regeneration in intervertebral discs	66
Quasi-dendritic sulfonate-based organic small molecule for high-quality NIR-II bone-targeted imaging	66
Photosynthetic bacteria-based whole-cell inorganic-biohybrid system for multimodal enhanced tumor radiotherapy	66
COPD airway epithelial cells–derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis	66
Advanced extracellular vesicle bioinformatic nanomaterials: from enrichment, decoding to clinical diagnostics	66
Biomimetic mesenchymal stem cell membrane-coated nanoparticle delivery of MKP5 inhibits hepatic fibrosis through the IRE/XBP1 pathway	66
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer	66
Mesenchymal stem cell-derived extracellular vesicles attenuate liver transplantation-induced ischemia/reperfusion injury by suppressing hepatocellular complement C5 expression	66
UiO-66 nanoparticles combat influenza A virus in mice by activating the RIG-I-like receptor signaling pathway	66
Targeted-theranostic nanoparticles induce anti-tumor immune response in lung cancer	66
Non-transgenic, PAMAM co-delivery DNA of interactive proteins NbCRVP and NbCalB endows Nicotiana benthamiana with a stronger antiviral effect to RNA viruses	65
PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer	65
Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation	65
Enhanced therapeutic effects of all-trans retinoic acid nanostructured lipid carrier composite gel drug delivery system for alopecia areata	65
Potentiating humoral and cellular immunity using a novel hybrid polymer-lipid nanoparticle adjuvant for HBsAg-VLP vaccine	65
Ultrasound-responsive nanocarriers with siRNA and Fe3O4 regulate macrophage polarization and phagocytosis for augmented non-small cell lung cancer immunotherapy	64
Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis	64
Injectable ROS-scavenging and NIR-responsive nanocomposite hydrogel for staphylococcus aureus-infected diabetic wound healing	64
Healthy young human plasma-derived exosomes enhance neural stem cell therapy by suppressing pyroptosis via TXNIP/NLRP3 after intracerebral hemorrhage	64
Ratiometric electrochemical OR gate assay for NSCLC-derived exosomes	64
Hypoxia-augmented chemotherapy potentiates imaging-guided combinatorial radionuclide-sonodynamic therapy for pancreatic cancer	64
Temporal and spatial resolution of magnetosome degradation at the subcellular level in a 3D lung carcinoma model	63
Role of actin cytoskeleton in cargo delivery mediated by vertically aligned silicon nanotubes	63
Drug repurposing: isosorbide mononitrate enhances tumor accumulation to augment sonodynamic therapy for hepatocellular carcinoma	63
Rod-like hybrid nanomaterial with tumor targeting and pH-responsive for cancer chemo/photothermal synergistic therapy	63
Brain-targeted nanoreactors prevent the development of organophosphate-induced delayed neurological damage	63
Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine	63
Outer membrane vesicles generated by an exogenous bacteriophage lysin and protection against Acinetobacter baumannii infection	63
Correction: Multifunctional nanobubbles carrying indocyanine green and paclitaxel for molecular imaging and the treatment of prostate cancer	62
Targeting VSMCs to suppress macrophage-like phenotype switching that restrains atherogenesis by immunosuppressive oligodeoxynucleotide (A151) functionalized selenium nanoparticles	62
Correction: Conditioning period impacts the morphology and proliferative effect of extracellular vesicles derived from rat adipose tissue derived stromal cell	62
Copper-coordinated engineered nanoreactors with self-amplifying O2 and cascade chem-drug synthesis for enhanced sonodynamic-mediated oncotherapy	62
Neutrophil membrane-camouflaged SiRNA nanoplatform targeting IL-33 attenuates osteoarthritis through autophagy-dependent senescence regulation	61
Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo	61
Selenium-loaded sustained-release schizophyllan alleviates pancreatic and pulmonary inflammatory damage in type 1 diabetes mellitus by modulating gut microbiota and T cell balance	61
Dual-pathway tumor radiosensitization strategy based on engineered bacteria capable of targeted delivery of AuNPs and specific hypoxia alleviation	60
Biodegradable and biocompatible exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging of tumors	60
Mechanistic insights into mRNA–LNP interactions: role of ionizable lipid content in regulating mRNA intracellular release and translation	60
Targeting YTHDF2 with pH-responsive siRNA nanoparticles suppresses MYC m6A modification and restores antitumor immunity in hepatocellular carcinoma	60
Magnesium-tannic acid nanomedicines reprogram pro-fibrotic macrophages for hepatic fibrosis treatment via restoring endoplasmic reticulum homeostasis	60
A living therapeutic platform for localized in situ modulation of macrophage pyroptosis ameliorates GVHD while preserving GVL	60
Endogenous and exogenous stimuli-driven intelligent nanocarriers: emerging strategies for the treatment of myocardial infarction	60
Leveraging the crosstalk between cGAS-STING and pyroptosis by nanomedicine to enhance antitumor immunity	60
Biomimetic proteolipid vesicles delivering small activating RNA to activate the macrophage immunotherapy for the treatment of lung cancer	59
Multifunctional vesicles in cancer therapy and theranostics: current advances and future challenges	59
Engineering antioxidant ceria-zirconia nanomedicines for alleviating podocyte injury in rats with adriamycin-induced nephrotic syndrome	59
Ultrasound nanodroplets loaded with Siglec-G siRNA and Fe3O4 activate macrophages and enhance phagocytosis for immunotherapy of triple-negative breast cancer	59
Single-cell and spatial transcriptomics reveal Thbs1-CD36 crosstalk between Kupffer and hepatic stellate cells following mesenchymal stem cell-derived small extracellular vesicles transplantation, all	59
Exosomal lncRNA Mir100hg from lung cancer stem cells activates H3K14 lactylation to enhance metastatic activity in non-stem lung cancer cells	59
Therapeutic potential of ADAR1-regulated macrophage exosomes for improving myocardial damage in septic cardiomyopathy	58
Folic acid-modified antigen-trapping nanoprobes for developing in situ tumor vaccines to inhibit metastasis and recurrence of ovarian cancer	58
Engineered pagoda-like dissolvable microneedle patches for synergistic photothermal antibacterial and wound regenerative therapy	58
ROS-responsive nanoliposomes loaded with anti-oomycetes medium-chain fatty acids for shuttling delivery in plant disease control	58
Ellagic acid-enhanced biocompatibility and bioactivity in multilayer core-shell gold nanoparticles for ameliorating myocardial infarction injury	58
Engineered neuronal exosomes mediate α-synuclein clearance to ameliorate Parkinson’s disease	58
Extracellular vesicle and particle biomarkers in cancer: a machine learning blueprint for liquid biopsy	58
Intelligent nanovesicle for remodeling tumor microenvironment and circulating tumor chemoimmunotherapy amplification	57
Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma	57
Single-atom Ca nanozyme induces glioma death through Ca2+-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment	57
AI-driven biomarker learning for the early diagnosis of neurodegenerative diseases: ABLEDx	57
Genetically engineered biomimetic ATP-responsive nanozyme for the treatment of cardiac fibrosis	57
Single-atom Zr doped heterojunction enhanced piezocatalysis for implant infection therapy through synergistic metal immunotherapy with sonodynamic and physical puncture	57
Ultrasound-activated piezoelectric Bi@Bi-MOF enables STING-mediated immunotherapy for implant-associated infections	57
Tumor targeting dendritic nanocarrier with immunogenic cell death inducing and TIGIT blockade for synergistic chemo-immunotherapy against TNBC	57
Engineering smart polymeric lipid nanoparticles for breast cancer: AI-guided formulation design, biological barriers, and translational constraints	56
Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis	56
Advanced drug delivery and therapeutic strategies for tuberculosis treatment	56
Medicinal plant-derived mtDNA via nanovesicles induces the cGAS-STING pathway to remold tumor-associated macrophages for tumor regression	56
Determining M2 macrophages content for the anti-tumor effects of metal-organic framework-encapsulated pazopanib nanoparticles in breast cancer	56
Intelligent ROS therapy driven by iron-based nanozyme with controllable catalytic activity for infected wound healing	56
Preferential activation of type I interferon-mediated antitumor inflammatory signaling by CuS/MnO2/diAMP nanoparticles enhances anti-PD-1 therapy for sporadic colorectal cancer	56
Repositioning of drugs for Parkinson’s disease and pharmaceutical nanotechnology tools for their optimization	56
Exosomes as drug delivery systems in glioma immunotherapy	56
Molecular mechanism differences between nanoplastics and microplastics in colon toxicity: nanoplastics induce ferroptosis-mediated immunogenic cell death, while microplastics cause cell metabolic repr	55
Photothermal reprogramming of synovial M1 macrophages reshapes the pro-inflammatory microenvironment to reverse temporomandibular joint osteoarthritis	55
Peptide-modified phase-transition nanoparticles co-deliver FTO siRNA and Ce6 for sonodynamic metabolism-immunotherapy of melanoma	55
High-precision detection and navigation surgery of colorectal cancer micrometastases	55
Bioactive VS4-based sonosensitizer for robust chemodynamic, sonodynamic and osteogenic therapy of infected bone defects	55
Plant-derived exosome-like nanovesicles: a novel therapeutic perspective for skin diseases	55
Tumor microenvironment responsive Mn-based nanoplatform activate cGAS-STING pathway combined with metabolic interference for enhanced anti-tumor therapy	55
Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage	55
Fluorescence-enhanced dual signal lateral flow immunoassay for flexible and ultrasensitive detection of monkeypox virus	54
Double-camouflaged tellurium nanoparticles for enhanced photothermal immunotherapy of tumor	54
MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy	54
Nanosilicates facilitate periodontal regeneration potential by activating the PI3K-AKT signaling pathway in periodontal ligament cells	54
Human umbilical cord mesenchymal stromal cell small extracellular vesicle transfer of microRNA-223-3p to lung epithelial cells attenuates inflammation in acute lung injury in mice	54
Spike structure of gold nanobranches induces hepatotoxicity in mouse hepatocyte organoid models	54
Frontier applications of retinal nanomedicine: progress, challenges and perspectives	54
Oxidative stress induced paclitaxel-derived carbon dots inhibit glioblastoma proliferation and EMT process	54