Organic & Biomolecular Chemistry

Papers
(The TQCC of Organic & Biomolecular Chemistry is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
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Contents list112
Au(iii)/TPPMS-catalyzed Friedel–Crafts benzylation of deactivated N-alkylanilines in water75
Visible light-mediated synthesis of quinazolinones and benzothiadiazine-1,1-dioxides utilizing aliphatic alcohols75
Synthesis of fused 3-trifluoromethyl-1,2,4-triazoles via base-promoted [3 + 2] cycloaddition of nitrile imines and 1H-benzo[d]imidazole-2-thiols72
Amine adducts of triallylborane as highly reactive allylborating agents for Cu(i)-catalyzed allylation of chiral sulfinylimines68
Flavin-induced charge separation in transmembrane model peptides65
Anthracene-isatoic anhydride hybrids for bioconjugation: chromophores with nucleophile dependent response63
Electrochemical alkylation of C(sp2)–H bonds via halogen-atom transfer (XAT) from alkyl iodides62
Total synthesis, stereochemical assignment, and biological evaluation of opantimycin A and analogues thereof61
N-Functionalized fluorophores: detecting urinary albumin and imaging lipid droplets58
Direct formylation of phenols using difluorocarbene as a safe CO surrogate57
A substrate-induced dual utilization cascade reaction of N-alkyl anilines: highly site-selective sustainable synthesis of chromeno[4,3-b]quinolin-6-ones57
Concise total synthesis of (±)-applanatumol Y56
DNA preference of indenoisoquinolines: a computational approach50
Design and synthesis of fluorescent-dye-labeled nucleotide with a new cleavable azo linker for DNA sequencing by synthesis46
Radical coupling of aryl halides to arenes facilitated by Ni(COD)(DQ) and other nickel sources44
Glyoxylic acid monohydrate promoted reductive addition of sodium sulfinates to pillar[4]arene[1]quinone43
3,5-Di(trifluoromethyl)phenyl(cyano)iodonium triflate as a novel and potential activator for p-tolyl thioglycoside donors41
Visible-light-mediated radical difunctionalization of alkenes with aromatic aldehydes41
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Lewis acid mediated allylation of vinyl diazonium ions by allylstannanes36
A rhodium-catalyzed cascade C–H activation/annulation strategy for the expeditious assembly of pyrrolidinedione-fused 1,2-benzothiazines36
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(Dimethylamino)methylene hydantoins as building blocks in the synthesis of oxoaplysinopsins and parabanic acids with antifungal activity35
On the divergent reactivity of allenylstannanes generated from the O-directed free radical hydrostannation reaction of (±)-trans-3-(2-phenylcyclopropyl)prop-2-yn-1-ol. EPR evidence for the reve34
Green and efficient synthesis of pure β-sulfonyl aliphatic sulfonyl fluorides through simple filtration in aqueous media33
Oxa-azabenzobenzocyclooctynes (O-ABCs): heterobiarylcyclooctynes bearing an endocyclic heteroatom33
Synthesis of mixed phosphorotrithioates via thiol coupling with bis(diisopropylamino)chlorophosphine and sulphenyl chloride33
Radical alkylation of acrylamides with peroxides to access mono/dialkylated fused N-heterocycles32
Recent progress in the homogeneous gold-catalysed cycloisomerisation reactions32
Base-promoted intermolecular cyclization of substituted 3-aryl-3-chloropropenals with tetrahydro-β-carboline: a method for the synthesis of indolizino[8,7- b 32
An electron donor–acceptor complex-initiated C–H trifluoromethylation and perfluoroalkylation of enamides and quinoxalinones32
Complementary strategies for synthesis of sulfinamides from sulfur-based feedstock31
Self-assembly of azamacrocyclic ligands into vesicular structures: from design to functional properties and applications30
Fluorescent α-amino acids via Heck–Matsuda reactions of phenylalanine-derived arenediazonium salts29
Substrate-controlled divergent synthesis of substituted carbazoles through a cascade reaction of 2-alkenylindoles with α,β-unsaturated ketones29
Recent advances in synthesis of stilbene derivativesviacross-coupling reaction29
Environmentally benign esterification and disproportionation using activation of acid anhydrides by molecular sieves 3A29
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Correction: Formal synthesis of cyclotheonellazole A28
Trivalent dialkylaminopyridine-catalyzed site-selective mono-O-acylation of partially-protected pyranosides28
Correction: C–H bond cyanation: electrochemical synthesis of phenylbenzimidoyl cyanide derivatives28
Synthesis of 3-sulfonylisoindolin-1-ones from olefinic amides and sodium sulfinates via electrooxidative tandem cyclization28
Flexible and rigid “chirally distorted” π-systems: binaphthyl conjugates as organic CPL-active chromophores27
A mitochondria-targeted colorimetric and NIR ratiometric fluorescent probe for biothiols with large Stokes shift based on thiol–chromene click reaction27
Multi-purpose thiocyanate protic ionic liquids in chemodivergent transformations of imidazolidin-2-(thi)one-based diols27
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Copper-catalyzed cross-coupling reaction of epoxides with allyl boron ester27
Metal-free quinoline synthesis via Brønsted acid-promoted cyclization of ene-ynamides26
High-throughput DoE synthesis of chalcones and pyrazolines for fluorescent sensing26
A macrocycle-based new organometallic nano-vessel towards sustainable C2-selective arylation of free indole in water26
Sumanene–carbazole conjugate with push–pull structure and its chemoreceptor application26
Aggregation induced emission and volatile acid vapour sensing in acridine appended poly (aryl ether) based low molecular weight organogelator26
Site-selective benzylic C–H hydroxylation in electron-deficient azaheterocycles25
Photochemistry of 2-(2-formylphenyloxy)acetic acid derivatives: synthesis of hydroxychromanones and benzofuranones25
Visible light-promoted cascade synthesis of pyrazolidinones via N-aryl glycine and azomethine imines25
Metal triflimide-mediated acylation of sulfonamides and transacylation of N -acylsulfonamides25
Direct C–H functionalisation of azoles via Minisci reactions25
Photodriven, TFA-promoted oxidative dehydrogenative coupling of quinoxalin-2(1 H )-ones with 5-pyrazolones25
Rapid paper-based optical sensing of Spilosoma obliqua nucleopolyhedrovirus via ester hydrolysis25
Practical synthesis of unsymmetrical disulfides promoted by bromodimethylsulfonium bromide25
Hydroboration of vinylsilanes providing diversity-oriented hydrophobic building blocks for biofunctional molecules25
Visible light-promoted C3–H alkoxycarbonylation of quinoxalin-2(1 H )-ones or coumarins with alkyloxalyl chlorides25
Investigating tedizolid analogues as a new class of herbicides24
Sequential condensation and double desulfonylative cyclopropanation of 1,2-bis(sulfonylmethyl)arenes with 3-arylacroleins: access to biscyclopropane-fused tetralins24
Structure–activity relationship of neplanocin A analogues for the identification of novel anti-HBV leads24
Photoredox-catalysed radical difluoromethylation/cyclization of N-acryloyl-2-arylbenzimidazole to access CF2H-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones24
Cu2O-mediated regio- and stereoselective one-pot synthesis of (Z)-3-ylidenephthalides from 2-iodobenzoic acids and terminal alkynes24
Intermolecular hydrogen bonding behavior of amino acid radical cations24
Synthesis of primary propargylic alcohols from terminal alkynes using rongalite as the C1 unit24
Transition metal-free one-pot tandem chemoselective reduction and cyclization of 3/5-(2-nitrophenyl)-1H-pyrazoles using sodium dithionite23
Sequential regioselective arylation of pyrazolones with diaryliodonium salts23
Chemistry of installing epitranscriptomic 5-modified cytidines in RNA oligomers23
Regioselective synthesis of enantiopure 1,2- and 1,3-dispirooxindoles along with a DFT study23
Recent applications of Cyrene as a chiral synthon23
Combining synthetic biology with synthetic electrochemistry to expand the chemical space of the indolocarbazole family23
Synthesis of optically active cyclopropanes by functionalization of cyclopropenes23
Unusual C-2 selectivity of Grignard additions to N -Boc-protected isatin 3-imines23
α-Alkylation of ketones with primary alcohols by an active non-noble metal Cu/CuOx catalyst23
Advances in the synthesis of rearranged homoisoflavonoids22
Mechanochemical deprotection of t -butoxycarbonyl (Boc) group using basic alumina22
Light-driven reductive cyclization catalyzed by vitamin B 12 -based artificial photoenzymes22
Total synthesis of (−)-griseocazine D2 and D322
Metallocenium incorporated charge-enhanced thiourea catalysts22
Photocatalyst-free synthesis of quinazolinones from o -aminobenzamides and rongalite under visible light22
Highly oxygenated steroids with immunosuppressive activity from Solanum undatum22
Design, synthesis and evaluation of antiproliferative effects of ferritin-targeted degraders21
Carboxylate migration from ethyl cyanoformate to methylene: rapid access toward pyrrolo[1,2- a ]pyrazines21
An efficient direct electrolysis method for the synthesis of 1,1,1,3,3,3-hexafluoroisopropyxy substituted imidazo[1,2-a]pyridines21
Bioorthogonal fluorogenic chemistry using a light-activated tetrazine21
Deciphering substitution effects on reductive hydroalkoxylation of alkynyl aminols for stereoselective synthesis of morpholines and 1,4-oxazepanes: total synthesis of tridemorph and fenpropimorph20
The boron effect on radical difluoromethylation of N-sulfonyl cyclic ketimines20
A novel synthetic method for backbone-cyclized polypeptide POL7080 with the help of hydrophobic-support materials20
Base-mediated synthesis of aryl enol ethers from α-aryl allylic alcohols and arylsulfonium salts20
Efficient construction of spirocyclopentane-1,3-dioxindoles via an annulation reaction of isocyanides and 3-methyleneoxindoles20
TropMol: a cloud-based web tool for virtual screening and early-stage prediction of acetylcholinesterase inhibitors using machine learning20
Diazo compounds: synthesis, carbene generation and reactivity20
Genome mining and heterologous expression reveal streptacidin, a new lasso peptide from Streptacidiphilus jiangxiensis20
Access to functionalized 2-pyrones through cascade reactions of α-halothioesters involving DBU-derived ammonium ylides20
Recent advances in Ugi reaction and its post-transformation strategies for crafting diverse indole frameworks20
Palladium-catalyzed α-arylation of sulfoxonium ylides with aryl fluorosulfates20
Light-induced ligand-to-metal charge transfer of Fe(iii)-OR species in organic synthesis19
Asymmetric synthesis of (R)-baclofen and (3S,4S)-tetflupyrolimet via “on water” organocatalytic addition reactions: a tip on catalyst screening19
Efficient synthesis of functionalized alkylidenephthalides, butenolides, pyranones, and isocoumarins via I 2 19
Design, synthesis, and biological evaluation of multiple F-18 S1PR1 radiotracers in rodent and nonhuman primate19
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Asymmetric synthesis of atropisomeric arylpyrazoles via direct arylation of 5-aminopyrazoles with naphthoquinones19
Photocatalytic radical addition/bicyclization of 1,7-enynes with N-sulfonylaminopyridinium salts/sulfamoyl chlorides: access to sulfonamide-containing benzo[a]fluoren-5-ones19
An imine condensation/1,5-electrocyclization cascade enabled permanent aldehyde–amine coupling through a triazole linkage19
A poly-pseudorotaxane constructed by threading pillar[5]arene onto an ion-pair recognition-based calix[4]pyrrole supramolecular polymer19
Recent advances in the organocatalytic enantioselective construction of alkynyl-containing tetrasubstituted carbon stereocenters19
Copper( ii ) nanodots stabilized on Cassia fistula galactomannan: preparation and catalytic applicatio19
Recent advances in the multicomponent synthesis of pyrazoles19
Butterflyene: an entry into an aesthetically pleasing carbocycle via a Diels–Alder reaction on a tetrasubstituted olefin19
Annulation of aliphatic nitro compounds with β-styryl sulfonium salts toward the synthesis of isoxazoline N -oxides19
Mechanochemical arylative detrifluoromethylation of trifluoromethylarenes18
Nonsilyl bicyclic secondary amine catalyzed Michael addition of nitromethane to β,β-disubstituted α,β-unsaturated aldehydes18
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A facile approach to phenothiazinones via catalytic aerobic oxidation: discovery of an antiproliferative agent18
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Albumin–ruthenium catalyst conjugate for bio-orthogonal uncaging of alloc group18
Dithioallyl cation (3 + 2) cycloadditions under aprotic reaction conditions: rapid access to spiro-fused cyclopentane scaffolds18
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InCl3 catalyzed simultaneous reductive sulfoximination and O-silylation: synthesis of silyloxy benzylsulfoximine18
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C–H activation-initiated spiroannulation reactions and their applications in the synthesis of spirocyclic compounds18
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Controllable conformation and reactivity of bicyclic α-methylene cyclopentanones and their NF-κB pathway inhibitory activity18
Enal-azomethine ylides: application in the synthesis of functionalized pyrroles18
N -Arylation of isatins with diaryliodonium salts under transition metal-free conditions17
Forging the tricyclic core framework of euphordraculoate B via a Barbier-type allyl addition17
Multifunctional supramolecular receptors: aqueous ion recognition, HCl sensing and cytotoxic potential17
Triaza-tricyclanos – synthesis of a new class of tricyclic nucleoside analogues by stereoselective cascade cyclocondensation17
Organocatalytic cyclization-rearrangement cascade reaction: asymmetric construction of γ-lactams17
Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors17
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An aromatic layered foldamer based on a ( cis , cis )-squaramide: chiral induction and absolute structure17
Copper-catalyzed enantioselective propargylic [3 + 2] cycloaddition: access to oxygen heterocycles featuring a CF3-substituted quaternary stereocenter17
Controlled packing of metal–peptide superhelices with β-peptide foldamers17
Electrochemically enabled oxidative aromatization of pyrazolines17
Access to functionalized benzo[ b ]fluorene/benzo[ a ]anthracene derivatives through TfOH-promoted tandem 17
P-Stereodefined morpholino dinucleoside 3′,5′-phosphorothioates17
Synthetic studies towards naturally occurring aporpinones: asymmetric synthesis of 1′-deshydroxymethyl analogues of aporpinone A, aporpinone B and 4′-hydroxyaporpinone A17
Submicromolar fluorescence ‘turn-on’ detection of fluoride anions using meso-(tetra-aryl) calix[4]pyrrole17
New P,Nsp3ligands for palladium-catalyzed asymmetric allylic substitutions17
Serine-mediated hydrazone ligation displaying insulin-like peptides on M13 phage pIII17
Synthesis of linear O-aryl carbamates and S-thiocarbamates via benign T3P-mediated condensation of phenols and thiols with amines and carbon dioxide17
Electrocatalytic selenocyclization for the synthesis of selenium-containing oxazolidinones17
Divergent synthetic studies towards bisabosqual A and fargenone B via an intramolecular S N 2 reaction17
Antiadhesive glycoconjugate metal complexes targeting pathogens Pseudomonas aeruginosa and Candida albicans17
Electrochemically enabled decyanative C(sp3)–H oxygenation of N-cyanomethylamines to formamides16
ION Thallos-HTL: a fluorescent thallium indicator that enables cell-selective and localizable thallium flux assays16
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Alkylation and silylation of α-fluorobenzyl anion intermediates16
Asymmetric synthesis of spiro[benzofuran-pyrrolidine]-indolinedione via bifunctional urea catalyzed [3 + 2]-annulation16
Development of an activity-based chemiluminogenic probe for γ-glutamylcyclotransferase16
Two short approaches to the COVID-19 drug β-d-N4-hydroxycytidine and its prodrug molnupiravir16
Synthesis of dihydrogambirtannine by alkyne [2 + 2 + 2]-cyclotrimerisation16
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Exploring α-electron-deficiency-induced [1,2]-fluorine migration16
Rh III -catalyzed C–H heteroarylation and C–N cleavage: direct access to C2-heteroarylated (NH)-indoles16
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ANRORC type rearrangement/intermolecular cyclocondensation cascade of 5,6-dicyano-3-(2-oxo-2-ethyl)pyrazin-2(1H)-ones with hydrazine hydrate for the synthesis of 2-(pyrazol-3-yl)imidazo[4,5-16
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Damage of amino acids by aliphatic peroxyl radicals: a kinetic and computational study16
Well-defined cobalt(ii)-catalyzed synthesis of perimidine derivatives via acceptorless dehydrogenative annulation16
Synthesis of fluorinated curcumin derivatives for detecting amyloid plaques by 19 F-MRI16
Strategies for the optimisation of troublesome peptide nucleic acid (PNA) sequences15
Reductive deoxygenation of tertiary alcohols: a cobalt-catalyzed hydrosilylation approach15
TiCl4-mediated deoxygenative reduction of aromatic ketones to alkylarenes with ammonia borane15
Ribosomal incorporation of N -acetyl-3,5-bis(chloromethyl)benzylthio- l -alanine for developing an mRN15
Multistep synthesis of cationic lipid-like compounds based on a difluorotetrahydropyridine scaffold as amphiphilic nanocarriers15
Formation of lignin alkyl-O-alkyl ether structures via 1,6-addition of aliphatic alcohols to β-O-4-aryl ether quinone methides15
Biocompatible silicomolybdic acid-promoted one-pot expeditious synthesis of 1,2,3- NH -triazoles15
Construction of a 1,2-diazetidine core based on a multicomponent reaction of N , N ′-(2,3-dimethylbutane-215
Computational insights into the origins of regio- and enantioselectivities in palladium-catalyzed allylic substitution reactions15
Straightforward access to α-carbonyloxy esters and β-keto thioethers from aryldiazoacetates15
Palladium-catalyzed 1,4-migration for the regioselective C–H bond functionalization at C2-position of 3-arylthiophenes15
“Cation Pool” generated from DMSO and 1,2-dihaloethanes and their application in organic synthesis15
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Azacoumarin-based “turn-on” fluorescent probe for the detection and imaging of hydrogen peroxide in living cells15
Pyrrolizinofluorene-embedded dithiacalixcorrole(1.0.1.1)s15
Supramolecular assembly of pyrene–DNA conjugates: influence of pyrene substitution pattern and implications for artificial LHCs15
Recent advances in photocatalytic and transition metal-catalyzed synthesis of disulfide compounds15
4,9- and 4,10-Substituted pyrenes: synthesis, successful isolation, and optoelectronic properties15
Rhodium(iii)-catalyzed C–H alkylation of arylhydrophthalazinediones with α-Cl ketones as sp3-carbon alkylated agents15
Photo-induced radical transformations of tosyl cyanide15
Reductive cross-coupling of N-acyl pyrazole and nitroarene using tetrahydroxydiboron: synthesis of secondary amides15
K2CO3-mediated annulation of 1,3-acetonedicarboxylates with 2-fluoro-1-nitroarenes: synthesis of indoles15
A HMPA–H2O mediated oxygenative carbocyclization of 2-alkynylphenyl-substituted p-quinone methides to indenones15
Transition metal-catalyzed transformations of 2-formylarylboronic acids15
Ethyl 3-bromopropanoate mediated tandem Knoevenagel–aldol annulation: a new strategy for the synthesis of indolizines15
Combinatorial synthesis of substituted pyrazolo-fused quinazolines by the Rh(iii)-catalyzed [5 + 1] annulation of phenyl-1H-pyrazol-5-amine with alkynoates and alkynamides15
HFIP-mediated C-3-alkylation of indoles and synthesis of indolo[2,3-b]quinolines & related natural products15
Development of the synthetic route to 5-hydroxymethyl tolterodine, a key synthetic intermediate of Toviaz, via an organic solvent-free Rh-catalyzed asymm15
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TsOH-catalyzed acyl migration reaction of the Bz-group: innovative assembly of various building blocks for the synthesis of saccharides14
BF3·OEt2-catalyzed/mediated alkyne cyclization: a comprehensive review of heterocycle synthesis with mechanistic insights14
Diastereoselective synthesis of trans-2,3-dihydroindoles via formal [4 + 1] annulation reactions of a sulfonium ylide14
Theoretical study of the rearrangement reaction in bisorbicillinoid biosynthesis: insights into the molecular mechanisms involved14
Access to 4-methylene-phospholenes through BF3·Et2O catalyzed isomerization of 3,4-dimethylphosphole sulfides14
Combining local conformational preferences and solvophobic effects in helical aromatic oligoamide foldamers14
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Nickel-catalyzed reductive cross-coupling of aziridines and benzyl chlorides14
A pathway to synthesize 2-methylbenzothiazole derivatives via a hydrogen sulfide promoted tandem reaction of calcium carbide and 2-iodoaniline14
Mechanistic characterisation of a fungal fusicoccane-type diterpene synthase involved in the biosynthesis of talaro-7,13-diene14
An NNN Pd( ii ) pincer complex with 1,1-diaminoazine: a versatile catalyst for acceptorless dehydrogenative coupling reactions14
Atropisomerism about aryl–C(sp3) bonds: chemically driven rotational pathway in cannabidiol derivatives14
Synthesis of tetrahydropyrrolo[1,2- a ]quinolinone analogues via CoCl 2 14
Coordination complexes of PIII-doped heterobuckybowls and their applications in catalysis14
Asymmetric total syntheses of passifetilactones A, C, E and 4-epi-passifetilactone B14
Highly efficient esterification of carboxylic acids with O–H nucleophiles through acid/iodide cooperative catalysis14
Synthesis of enantioenriched spirocyclic 2-arylpiperidines via kinetic resolution14
Phthalimide-based sulfur transfer reagents for the preparation of biologically relevant trisulfides14
Visible-light promoted oxidative annulation of 2-naphthols with phenylglyoxal monohydrates toward hydroxy-naphthofuranone and its derivatives14
Cyclopropanation reactions by a class I unspecific peroxygenase14
Substituted anilides from chitin-based 3-acetamido-furfural14
Pretzelanes, [1]rotaxanes and molecular figures-of-eight – crossing the bridge from fundamentals to functional applications13
Highly efficient fixation of carbon dioxide into 2-oxazolidinones under mild conditions by using a reusable ionic liquid/CuI catalyst system13
One-pot synthesis of sulfonyl 3,6-diarylpyridazines via tandem condensation of α-sulfonyl ketones with methyl ketones13
Bicyclic nucleoside analogues: synthesis of thiazolopyrimidine-based nucleosides via a copper-catalysed tandem reaction of 5-iodocytidine with isothiocyanates13
Cu@g-C 3 N 4 heterojunction-catalyzed visible-light-driven direct C–H alkylation of heterocycles13
Photoinduced halogen-bonding enabled synthesis of oxindoles and isoindolinones from aryl iodides13
Chiral recognition of organoselenium compounds: an update13
Sequential nucleophilic aromatic substitutions on cyanuric chloride: synthesis of BODIPY derivatives and mechanistic insights13
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A fluorescent probe for selective detection of boric acids and its application for screening the conversion of the Suzuki–Miyaura coupling reaction13
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Green light-mediated dual eosin Y/PdII-catalyzed C(sp2)–H arylation of N–H unprotected 2-arylquinazolinones13
Racemic peptide assembly boosts biocatalysis13
Synthesis of masked α,β-unsaturated trifluoromethyl ketones via iodine( iii )-mediated double decarbox13
A regioselective synthesis of β-difluoromethoxy vinyl sulfonesvia O-difluoromethylation of β-ketosulfones using sodium chlorodifluoroacetate13
Synthesis of cinnamic esters and acids via palladium-catalyzed reactions of aryl diazonium salts and their biological evaluation13
Efficient synthesis of tetrahydroquinolines via selective reduction of quinolines with copper salts and silanes13
N-Confused strapped calix[4]pyrrole: the missing member of calix[4]pyrrole chemistry13
Catalytic I2-moist DMSO-mediated synthesis of valuable α-amidohydroxyketones and unsymmetrical gem-bisamides from benzimidates13
BF3·Et2O controlled selective synthesis of α-substituted propargylamides and β-(N-acylamino) ketones: application to carbon and sulphur nucleophiles13
Samarium diiodide/samarium-mediated direct deoxygenative hydroborylation of ketones with hydroborane esters13
Sequential detection of inflammation-related hypochlorite ions and viscosity with a relay fluorescent probe13
Synthesis of tetracyclic dibenzo[b,f][1,4]oxazepine-fused β-lactams via visible-light-induced Staudinger annulation13
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