Neoplasia

Papers
(The TQCC of Neoplasia is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Epitranscriptomic mechanisms of androgen signalling and prostate cancer1343
ARID1A loss sensitizes colorectal cancer cells to floxuridine101
Single cell analysis unveils the commonality and heterogeneity between nasopharyngeal and oropharyngeal carcinoma80
Visualizing mast cell migration to tumor sites using sodium iodide symporter of nuclear medicine reporter gene68
Corrigendum to “Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells” [Neoplasia 17 (2014) 85]58
Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma55
Corrigendum to “Tumorigenicity of IL-1α- and IL-1β-Deficient Fibrosarcoma Cells” [Neoplasia, Volume 10, Issue 6, June 2008, Pages 549–562]47
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis45
5-Aza-2′-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD44
The GSK3 kinase and LZTR1 protein regulate the stability of Ras family proteins and the proliferation of pancreatic cancer cells42
RUNX2 enhances bladder cancer progression by promoting glutamine metabolism39
Tumor-Infiltrating Immune Cells in Colorectal Cancer37
Combined radio-immunotherapy: An opportunity to increase the therapeutic ratio of oligometastasis-directed radiotherapy36
Role of heparanase 2 (Hpa2) in gastric cancer34
Combination of sunitinib and 177Lu-labeled antibody cG250 targeted radioimmunotherapy: A promising new therapeutic strategy for patients with advanced renal cell cancer33
Mutational signatures and their association with survival and gene expression in urological carcinomas33
Retraction notice to “Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors” [Neoplasia 18 (2016) 347- 355/201]33
Myxoid glioneuronal tumor: Histopathologic, neuroradiologic, and molecular features in a single center series33
Time-restricted feeding affects the fecal microbiome metabolome and its diurnal oscillations in lung cancer mice32
From adenoma to CRC stages: the oral-gut microbiome axis as a source of potential microbial and metabolic biomarkers of malignancy31
Advanced progress of spatial metabolomics in head and neck cancer research31
Lactate promoted cisplatin resistance in NSCLC by modulating the m6A modification-mediated FOXO3/MAGI1-IT1/miR-664b-3p/IL-6R axis30
The role of glycolysis in tumorigenesis: From biological aspects to therapeutic opportunities30
Leptomeningeal dissemination in pediatric brain tumors30
Colorectal cancer, Vitamin D and microbiota: A double-blind Phase II randomized trial (ColoViD) in colorectal cancer patients30
STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications29
Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations28
Identification of recurrent BRAF non-V600 mutations in intraductal carcinoma of the prostate in Chinese populations28
Molecular subtypes based on CNVs related gene signatures identify candidate prognostic biomarkers in lung adenocarcinoma27
Epigenetic DNA modifications and vitamin C in prostate cancer and benign prostatic hyperplasia: Exploring similarities, disparities, and pathogenic implications27
PDGF-BB overexpression in p53 null oligodendrocyte progenitors increases H3K27me3 and induces transcriptional changes which favor proliferation26
Incidence, mortality, and global burden of retinoblastoma in 204 countries worldwide from 1990 to 2021: Data and systematic analysis from the Global Burden of Disease Study 202126
Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes25
Longitudinal genomic alternations and clonal dynamics analysis of primary malignant melanoma of the esophagus25
Aurkin-A, a TPX2-Aurora A small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma25
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis25
Reciprocal regulation of lncRNA MEF and c-Myc drives colorectal cancer tumorigenesis25
Tumor-associated macrophages promote bladder cancer metastasis through the CCL20-CCR6 axis24
Ovulation sources coagulation protease cascade and hepatocyte growth factor to support physiological growth and malignant transformation23
An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors23
MET inhibition downregulates DR4 expression in MET-amplified lung cancer cells with acquired resistance to EGFR inhibitors through suppressing AP-1-mediated transcription22
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR22
A systematic review of microbiome-derived biomarkers for early colorectal cancer detection22
HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma21
Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4,21
Medication adjustment of afatinib and combination therapy with sitagliptin for alleviating afatinib-induced diarrhea in rats20
Corrigendum to “SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT Pathway” [Neoplasia (2021) 23, 1037–1047]20
Pediatric neuro-oncology: Highlights of the last quarter-century20
Aurora kinase B is required for growth and expansion of medulloblastoma cells in the tissue context20
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating treatment18
Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord models early events in ERK-mediated tumorigenesis18
Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature18
Inhibiting HnRNP L-mediated alternative splicing of EIF4G1 counteracts immune checkpoint blockade resistance in Castration-resistant prostate Cancer18
Amelioration of muscle wasting by gintonin in cancer cachexia17
SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer17
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)17
Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement17
Acral melanoma: new insights into the immune and genomic landscape17
MYH knockdown in pancreatic cancer cells creates an exploitable DNA repair vulnerability16
Whole-chromosome arm acquired uniparental disomy in cancer development is a consequence of isochromosome formation16
A bioluminescence reporter mouse model for visualizing and quantifying CD8+ T cells in vivo16
Targeting glycan sulfation in a CD11c+ myeloid population inhibits early KRAS-mutant lung neoplasia15
BRAF p.V600E mutation as a molecular boundary between genuine oligo-repeated and poly-metastatic disease in colorectal cancer15
Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/515
IGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in MDA-MB-231 metastatic breast cancer cells15
Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening15
Spatial profiling of METex14-altered NSCLC under tepotinib treatment: Shifting the immunosuppressive landscape15
Early separation and parallel clonal selection of dedifferentiated and well-differentiated components in dedifferentiated liposarcoma15
Cell competition, cooperation, and cancer14
Carcinogenesis induced by space radiation: A systematic review14
PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome14
PBI-05204, a supercritical CO2 extract of Nerium oleander, suppresses glioblastoma stem cells by inhibiting GRP78 and inducing programmed necroptotic cell death14
Structure and function of the lysine methyltransferase SETD2 in cancer: From histones to cytoskeleton14
miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients14
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma14
High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer14
Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor14
mTORC2 regulates ribonucleotide reductase to promote DNA replication and gemcitabine resistance in non-small cell lung cancer13
Unveiling the impact of SUMOylation at K298 site of heat shock factor 1 on glioblastoma malignant progression13
Current state of pediatric neuro-oncology imaging, challenges and future directions13
Corrigendum to “Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma” [Neoplasia, Volume 21, Issue 3 (2019) 322–330]13
SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets13
Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.13
Targeting myeloma metabolism: How abnormal metabolism contributes to multiple myeloma progression and resistance to proteasome inhibitors13
Metformin use and survival in people with ovarian cancer: A population-based cohort study from British Columbia, Canada13
Corrigendum to “NFAT1 hypermethylation promotes epithelial‐mesenchymal transition and metastasis in nasopharyngeal carcinoma by activating ITGA6 transcription” [Neoplasia 21 (2019): 311–321]13
Combining selinexor with alisertib to target the p53 pathway in neuroblastoma13
Bacterial translocation and barrier dysfunction enhance colonic tumorigenesis12
Corrigendum to “Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL” [Neoplasia. Vol. 9, No. 5, May 2007, pp. 435–442]12
FAPα and αSMA mark different subsets of fibroblasts in normal kidney and conventional renal cell carcinoma12
Impact of tissue penetration and albumin binding on design of T cell targeted bispecific agents12
Therapeutic effiacy of T cells expressing chimeric antigen receptor derived from a mesothelin-specific scFv in orthotopic human pancreatic cancer animal models12
CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation12
mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics12
LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD4412
Genomics driven precision oncology in advanced biliary tract cancer improves survival12
Proteomic profiling of canine fibrosarcoma and adjacent peritumoral tissue12
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma12
Phase I clinical trial of a novel procaspase-3 activator SM-1 with temozolomide in recurrent high-grade gliomas11
DARPP-32 and t-DARPP in the development of resistance to anti-HER2 agents. Pre-clinical evidence from the STEP study11
Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinases11
Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells11
Reduction in mitochondrial oxidative stress mediates hypoxia-induced resistance to cisplatin in human transitional cell carcinoma cells11
The renal clear cell carcinoma immune landscape11
Regulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells after treatment with dutasteride and lovastatin11
Synergizing radiotherapy and immunotherapy: Current challenges and strategies for optimization11
The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia10
Metformin combined with cisplatin reduces anticancer activity via ATM/CHK2-dependent upregulation of Rad51 pathway in ovarian cancer10
Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer10
Short chain fatty acids delay the development of hepatocellular carcinoma in HBx transgenic mice10
AEBP1 promotes papillary thyroid cancer progression by activating BMP4 signaling10
Spatial distribution of immune checkpoint proteins in histological subtypes of lung adenocarcinoma10
ΔNp63 silencing, DNA methylation shifts, and epithelial-mesenchymal transition resulted from TAp63 genome editing in squamous cell carcinoma10
Comprehensive profiling of EGFR mutation subtypes reveals genomic-clinical associations in non-small-cell lung cancer patients on first-generation EGFR inhibitors10
RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells10
Furin, ADAM, and γ-secretase: Core regulatory targets in the Notch pathway and the therapeutic potential for breast cancer10
Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition10
Naproxen inhibits spontaneous lung adenocarcinoma formation in KrasG12V mice10
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