Neoplasia

Papers
(The TQCC of Neoplasia is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
UALCAN: An update to the integrated cancer data analysis platform973
ONC201 and imipridones: Anti-cancer compounds with clinical efficacy101
Development and prevalence of castration-resistant prostate cancer subtypes83
ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma82
Glycolysis-induced drug resistance in tumors—A response to danger signals?58
STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications58
Exosomal lncRNA NEAT1 from cancer-associated fibroblasts facilitates endometrial cancer progression via miR-26a/b-5p-mediated STAT3/YKL-40 signaling pathway52
The forces driving cancer extracellular vesicle secretion48
SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets48
Evaluating patient-specific neoadjuvant regimens for breast cancer via a mathematical model constrained by quantitative magnetic resonance imaging data43
Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis43
Tumor necrosis factor in lung cancer: Complex roles in biology and resistance to treatment41
Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses39
Short chain fatty acids delay the development of hepatocellular carcinoma in HBx transgenic mice36
Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era36
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine35
Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping34
MiR-944/CISH mediated inflammation via STAT3 is involved in oral cancer malignance by cigarette smoking34
Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis33
Predicting patient-specific response to adaptive therapy in metastatic castration-resistant prostate cancer using prostate-specific antigen dynamics33
The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science33
Bone marrow mesenchymal stem cells interact with head and neck squamous cell carcinoma cells to promote cancer progression and drug resistance30
Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells29
Cholesterol and saturated fatty acids synergistically promote the malignant progression of prostate cancer29
Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT328
EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG27
Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery27
Spatiotemporal trends of the global burden of melanoma in 204 countries and territories from 1990 to 2019: Results from the 2019 global burden of disease study26
Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer25
Copy number variation in triple negative breast cancer samples associated with lymph node metastasis25
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis25
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating treatment24
Hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis24
Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system24
Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival23
Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability23
Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells23
Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathway23
Microbiota-driven mechanisms at different stages of cancer development23
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin22
Noninvasive multiparametric characterization of mammary tumors with transmission-reflection optoacoustic ultrasound22
A systematic review of microbiome-derived biomarkers for early colorectal cancer detection22
Diet-microbiome interactions in cancer treatment: Opportunities and challenges for precision nutrition in cancer22
Fusobacterium nucleatum stimulates cell proliferation and promotes PD-L1 expression via IFIT1-related signal in colorectal cancer21
A systemic review of the role of enterotoxic Bacteroides fragilis in colorectal cancer21
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L121
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)21
Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut20
Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer20
mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics20
P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK920
The paradox of radiation and T cells in tumors20
Molecular and genetic biomarkers implemented from next-generation sequencing provide treatment insights in clinical practice for Waldenström macroglobulinemia20
Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy20
Non-melanoma skin cancers: physio-pathology and role of lipid delivery systems in new chemotherapeutic treatments19
Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow19
Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair19
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity18
The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma18
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway17
A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML17
Cancer: A turbulence problem17
Carcinogenesis induced by space radiation: A systematic review16
CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation16
Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [18F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression16
Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway16
Unsupervised machine learning using K-means identifies radiomic subgroups of pediatric low-grade gliomas that correlate with key molecular markers15
Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety15
Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages15
c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells15
Lysyl hydroxylase 2-induced collagen cross-link switching promotes metastasis in head and neck squamous cell carcinomas15
Hypoxia theranostics of a human prostate cancer xenograft and the resulting effects on the tumor microenvironment15
Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription15
The p53-inducible CLDN7 regulates colorectal tumorigenesis and has prognostic significance15
Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis15
Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4,14
Synergizing radiotherapy and immunotherapy: Current challenges and strategies for optimization14
Injured tissues favor cancer cell implantation via fibrin deposits on scar zones14
A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma14
Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting14
Targeting interleukin 4 receptor alpha on tumor-associated macrophages reduces the pro-tumor macrophage phenotype14
Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations14
From adenoma to CRC stages: the oral-gut microbiome axis as a source of potential microbial and metabolic biomarkers of malignancy13
Molecular homology between canine spontaneous oral squamous cell carcinomas and human head-and-neck squamous cell carcinomas reveals disease drivers and therapeutic vulnerabilities13
The breast tissue microbiome, stroma, immune cells and breast cancer13
Colorectal cancer, Vitamin D and microbiota: A double-blind Phase II randomized trial (ColoViD) in colorectal cancer patients13
STAMBP promotes lung adenocarcinoma metastasis by regulating the EGFR/MAPK signaling pathway13
Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localization13
Inhibition of fibronectin accumulation suppresses tumor growth13
Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma13
Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis13
Nuclear morphology predicts cell survival to cisplatin chemotherapy13
Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition13
Targeted and explorative profiling of kallikrein proteases and global proteome biology of pancreatic ductal adenocarcinoma, chronic pancreatitis, and normal pancreas highlights disease-specific proteo12
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer12
Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization12
Noninvasive optoacoustic microangiography reveals dose and size dependency of radiation-induced deep tumor vasculature remodeling12
SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma12
Understanding the roles of N6-methyladenosine writers, readers and erasers in breast cancer12
Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer12
Eucannabinolide, a novel sesquiterpene lactone, suppresses the growth, metastasis and BCSCS-like traits of TNBC via inactivation of STAT312
Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells12
The anti-B7-H4 checkpoint synergizes trastuzumab treatment to promote phagocytosis and eradicate breast cancer12
Spectroscopic investigation of radiation-induced reoxygenation in radiation-resistant tumors12
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP5311
Hepatocellular carcinoma-derived FOXO1 inhibits tumor progression by suppressing IL-6 secretion from macrophages11
Identification of disease-promoting stromal components by comparative proteomic and transcriptomic profiling of canine mammary tumors using laser-capture microdissected FFPE tissue11
Proteome biology of primary colorectal carcinoma and corresponding liver metastases11
High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity11
PAD4-dependent citrullination of nuclear translocation of GSK3β promotes colorectal cancer progression via the degradation of nuclear CDKN1A11
PEGPH20, a PEGylated human hyaluronidase, induces radiosensitization by reoxygenation in pancreatic cancer xenografts. A molecular imaging study11
miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma11
Combining selinexor with alisertib to target the p53 pathway in neuroblastoma11
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