OOIR: Observatory of International Research

Papers

(The TQCC of Neoplasia is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
UALCAN: An update to the integrated cancer data analysis platform	676
ONC201 and imipridones: Anti-cancer compounds with clinical efficacy	84
Development and prevalence of castration-resistant prostate cancer subtypes	65
ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma	63
Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor	59
Glycolysis-induced drug resistance in tumors—A response to danger signals?	53
A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo	43
STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications	43
Exosomal lncRNA NEAT1 from cancer-associated fibroblasts facilitates endometrial cancer progression via miR-26a/b-5p-mediated STAT3/YKL-40 signaling pathway	42
The forces driving cancer extracellular vesicle secretion	41
Evaluating patient-specific neoadjuvant regimens for breast cancer via a mathematical model constrained by quantitative magnetic resonance imaging data	40
SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets	40
Tumor necrosis factor in lung cancer: Complex roles in biology and resistance to treatment	37
Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses	34
MiR-944/CISH mediated inflammation via STAT3 is involved in oral cancer malignance by cigarette smoking	32
MKL1/miR-5100/CAAP1 loop regulates autophagy and apoptosis in gastric cancer cells	32
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine	32
Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis	32
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α	31
Predicting patient-specific response to adaptive therapy in metastatic castration-resistant prostate cancer using prostate-specific antigen dynamics	31
Prostate cancer-derived MMP-3 controls intrinsic cell growth and extrinsic angiogenesis	30
Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis	30
Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping	30
Short chain fatty acids delay the development of hepatocellular carcinoma in HBx transgenic mice	29
Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells	27

Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3	26
EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG	24
Bone marrow mesenchymal stem cells interact with head and neck squamous cell carcinoma cells to promote cancer progression and drug resistance	24
Cholesterol and saturated fatty acids synergistically promote the malignant progression of prostate cancer	22
Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer	22
Spatiotemporal trends of the global burden of melanoma in 204 countries and territories from 1990 to 2019: Results from the 2019 global burden of disease study	22
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis	22
Copy number variation in triple negative breast cancer samples associated with lymph node metastasis	21
An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis	21
The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science	21
LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase	21
Targeting AGTR1/NF-κB/CXCR4 axis by miR-155 attenuates oncogenesis in glioblastoma	21
Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival	20
mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics	20
Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery	20
Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells	19
A systemic review of the role of enterotoxic Bacteroides fragilis in colorectal cancer	19
Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy	19
Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut	19
Noninvasive multiparametric characterization of mammary tumors with transmission-reflection optoacoustic ultrasound	19
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin	18
Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes	18
Molecular and genetic biomarkers implemented from next-generation sequencing provide treatment insights in clinical practice for Waldenström macroglobulinemia	18
Hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis	18
Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4	17
Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma	17
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating treatment	17
Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathway	16
PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1	16
Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability	15
The p53-inducible CLDN7 regulates colorectal tumorigenesis and has prognostic significance	15
Hypoxia theranostics of a human prostate cancer xenograft and the resulting effects on the tumor microenvironment	15
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity	15
P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9	15
Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system	15
Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow	15
CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation	15
Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair	15
A systematic review of microbiome-derived biomarkers for early colorectal cancer detection	14
Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion	14
Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages	14
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)	14
Diet-microbiome interactions in cancer treatment: Opportunities and challenges for precision nutrition in cancer	14
Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells	13
Microbiota-driven mechanisms at different stages of cancer development	13
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway	13
Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis	13
Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [18F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression	13
Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer	13
BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases	13

A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML	13
Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway	13
TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance	13
Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era	13
Prognostic alternative mRNA splicing signatures and associated splicing factors in acute myeloid leukemia	12
The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma	12
Targeting interleukin 4 receptor alpha on tumor-associated macrophages reduces the pro-tumor macrophage phenotype	12
Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis	12
Lysyl hydroxylase 2-induced collagen cross-link switching promotes metastasis in head and neck squamous cell carcinomas	12
The anti-B7-H4 checkpoint synergizes trastuzumab treatment to promote phagocytosis and eradicate breast cancer	12
Cancer: A turbulence problem	12
Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition	12
c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells	12
Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localization	12
SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma	12
High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study	12
Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription	11
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer	11
Understanding the roles of N6-methyladenosine writers, readers and erasers in breast cancer	11
Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4,	11
Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells	11
Deep tissue volumetric optoacoustic tracking of individual circulating tumor cells in an intracardially perfused mouse model	11
Fusobacterium nucleatum stimulates cell proliferation and promotes PD-L1 expression via IFIT1-related signal in colorectal cancer	11
STAMBP promotes lung adenocarcinoma metastasis by regulating the EGFR/MAPK signaling pathway	11
Combining selinexor with alisertib to target the p53 pathway in neuroblastoma	11