Neoplasia

Papers
(The TQCC of Neoplasia is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Filamin a binds deleted in liver cancer 1 (DLC1) to promote its tumor suppressor activity and inhibit the SRF coactivator MRTF-A84
Visualizing mast cell migration to tumor sites using sodium iodide symporter of nuclear medicine reporter gene82
Corrigendum to “Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells” [Neoplasia 17 (2014) 85]80
Corrigendum to “Tumorigenicity of IL-1α- and IL-1β-Deficient Fibrosarcoma Cells” [Neoplasia, Volume 10, Issue 6, June 2008, Pages 549–562]75
Single cell analysis unveils the commonality and heterogeneity between nasopharyngeal and oropharyngeal carcinoma70
5-Aza-2′-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD60
DHX34 deficiency triggers tumor-intrinsic immunity via a dsRNA-mediated type I interferon pathway activation in HCC56
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis55
ARID1A loss sensitizes colorectal cancer cells to floxuridine51
Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG)49
Epitranscriptomic mechanisms of androgen signalling and prostate cancer49
L-methionine promotes CD8+ T cells killing hepatocellular carcinoma by inhibiting NR1I2/PCSK9 signaling46
High metastatic tumor-derived CXCL16 mediates liver colonization metastasis by inducing Kupffer cell polarization via the PI3K/AKT/FOXO3a pathway45
Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma43
Myxoid glioneuronal tumor: Histopathologic, neuroradiologic, and molecular features in a single center series43
Combination of sunitinib and 177Lu-labeled antibody cG250 targeted radioimmunotherapy: A promising new therapeutic strategy for patients with advanced renal cell cancer41
CCAAT‐enhancer binding protein delta functions as a tumor suppressor gene in acute myeloid leukemia40
Time-restricted feeding affects the fecal microbiome metabolome and its diurnal oscillations in lung cancer mice37
Retraction notice to “Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors” [Neoplasia 18 (2016) 347- 355/201]37
RUNX2 enhances bladder cancer progression by promoting glutamine metabolism36
From adenoma to CRC stages: the oral-gut microbiome axis as a source of potential microbial and metabolic biomarkers of malignancy36
Mutational signatures and their association with survival and gene expression in urological carcinomas36
Tumor-Infiltrating Immune Cells in Colorectal Cancer36
New horizons in B-cell lymphoma immunotherapy: From immune checkpoints to precision medicine35
BPGM as an intrinsic brake to constrain metastasis through phospho-epigenetic-mediated carnitine biosynthesis suppression34
Metabolic and imaging phenotypes associated with RB1 and TP53 loss in prostate cancer34
Rezatapopt: A promising small-molecule “refolder” specific for TP53Y220C mutant tumors34
The role of glycolysis in tumorigenesis: From biological aspects to therapeutic opportunities32
Identification of recurrent BRAF non-V600 mutations in intraductal carcinoma of the prostate in Chinese populations32
A spatiotemporal atlas of orchiectomy-induced androgen deprivation-mediated modulation of cellular composition and gene expression in the mouse prostate31
Advanced progress of spatial metabolomics in head and neck cancer research30
PDGFRα governs multiple cellular signals and plays a protective role in tumor progression29
Regulatory mechanisms of the Hippo/YAP axis by G-protein coupled estrogen receptor in gastric signet-ring cell carcinoma28
Colorectal cancer, Vitamin D and microbiota: A double-blind Phase II randomized trial (ColoViD) in colorectal cancer patients28
Epigenetic DNA modifications and vitamin C in prostate cancer and benign prostatic hyperplasia: Exploring similarities, disparities, and pathogenic implications28
Lactate promoted cisplatin resistance in NSCLC by modulating the m6A modification-mediated FOXO3/MAGI1-IT1/miR-664b-3p/IL-6R axis28
Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations27
Leptomeningeal dissemination in pediatric brain tumors27
Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes26
An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors26
Corrigendum to: The SRSF3-MBNL1-Acin1 circuit constitutes an emerging axis to lessen DNA fragmentation in colorectal cancer via an alternative splicing mechanism26
Aurkin-A, a TPX2-Aurora A small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma25
PRAS40 activates the IRE1α-XBP-1-mediated unfolded protein response to exacerbate colorectal cancer by enhancing ST6Gal1-dependent α-2, 6 sialylation of GRP7825
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR25
Tumor-associated macrophages promote bladder cancer metastasis through the CCL20-CCR6 axis24
Single-cell proteomic analysis reveals Multiple Myeloma heterogeneity and the dynamics of the tumor immune microenvironment in precursor and advanced states24
Reciprocal regulation of lncRNA MEF and c-Myc drives colorectal cancer tumorigenesis24
PDGF-BB overexpression in p53 null oligodendrocyte progenitors increases H3K27me3 and induces transcriptional changes which favor proliferation24
Incidence, mortality, and global burden of retinoblastoma in 204 countries worldwide from 1990 to 2021: Data and systematic analysis from the Global Burden of Disease Study 202123
Longitudinal genomic alternations and clonal dynamics analysis of primary malignant melanoma of the esophagus23
Aurora kinase B is required for growth and expansion of medulloblastoma cells in the tissue context23
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis23
A systematic review of microbiome-derived biomarkers for early colorectal cancer detection23
Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement22
Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature22
Corrigendum to “SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT Pathway” [Neoplasia (2021) 23, 1037–1047]22
Medication adjustment of afatinib and combination therapy with sitagliptin for alleviating afatinib-induced diarrhea in rats22
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)21
HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma21
Enhancing the antitumor efficacy using a combination of FGFR4 Inhibitor (H3B-6527) and oxaliplatin in gastric cancer21
Acral melanoma: new insights into the immune and genomic landscape21
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating treatment20
The DNA mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression20
Inhibiting HnRNP L-mediated alternative splicing of EIF4G1 counteracts immune checkpoint blockade resistance in Castration-resistant prostate Cancer20
SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer20
PBI-05204, a supercritical CO2 extract of Nerium oleander, suppresses glioblastoma stem cells by inhibiting GRP78 and inducing programmed necroptotic cell death19
High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype19
Characterizing the impact of MLL fusion variants and fusion partners on leukemia plasticity using a human CRISPR-engineered MLL-rearranged leukemia model19
IGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in MDA-MB-231 metastatic breast cancer cells19
Pediatric neuro-oncology: Highlights of the last quarter-century19
BRAF p.V600E mutation as a molecular boundary between genuine oligo-repeated and poly-metastatic disease in colorectal cancer18
Spatial profiling of METex14-altered NSCLC under tepotinib treatment: Shifting the immunosuppressive landscape18
Experimental study of tumor-associated macrophage-derived SPP1 inhibit CD8+ T cells to promote Colorectal cancer progression18
Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening17
Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/517
MYH knockdown in pancreatic cancer cells creates an exploitable DNA repair vulnerability17
High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer17
Comparative effects of combustible cigarette versus electronic cigarette exposures on KRAS mutant lung cancer promotion17
Carcinogenesis induced by space radiation: A systematic review16
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma16
PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome16
Early separation and parallel clonal selection of dedifferentiated and well-differentiated components in dedifferentiated liposarcoma16
Structure and function of the lysine methyltransferase SETD2 in cancer: From histones to cytoskeleton16
Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor16
Microbial crosstalk along the oral–gut axis: organ-specific oncogenic adaptations of Porphyromonas gingivalis and Fusobacterium nucleatum16
Clonal architecture of FLT3-ITD and acquired 13q uniparental disomy define prognostic heterogeneity and therapeutic vulnerabilities in acute myeloid leukemia15
Corrigendum to “Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma” [Neoplasia, Volume 21, Issue 3 (2019) 322–330]15
Current state of pediatric neuro-oncology imaging, challenges and future directions15
Dynasore as a dual modulator of lipid rafts and cell death in pancreatic cancer15
Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.14
Targeting myeloma metabolism: How abnormal metabolism contributes to multiple myeloma progression and resistance to proteasome inhibitors14
Dual CDK4/6–PI3K/mTOR inhibition reinforces cytostatic programs and tumor control in preclinical models of primary and metastatic osteosarcoma14
Unveiling the impact of SUMOylation at K298 site of heat shock factor 1 on glioblastoma malignant progression14
Metformin use and survival in people with ovarian cancer: A population-based cohort study from British Columbia, Canada14
Systemic inflammation in response to radiation drives the genesis of an immunosuppressed tumor microenvironment14
PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy14
Bacterial translocation and barrier dysfunction enhance colonic tumorigenesis14
Genomics driven precision oncology in advanced biliary tract cancer improves survival14
Impact of tissue penetration and albumin binding on design of T cell targeted bispecific agents13
FAPα and αSMA mark different subsets of fibroblasts in normal kidney and conventional renal cell carcinoma13
Proteomic profiling of canine fibrosarcoma and adjacent peritumoral tissue13
Oral bioavailable ITRI-148 degrades androgen receptor variants and overcomes antiandrogen resistance in advanced prostate cancer13
From inflammation to malignancy: the dynamic evolution of cancer-associated fibroblasts in IBD-CRC13
Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer13
Tamoxifen promotes metastasis of breast cancer via reshaping lipid-driven fibrotic microenvironments in the lung13
LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD4413
Motion based ex vivo (MOTEX) culture of breast tumor slices sustains microenvironment composition13
Corrigendum to “Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL” [Neoplasia. Vol. 9, No. 5, May 2007, pp. 435–442]13
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma13
CYP1B1 promotes angiogenesis and sunitinib resistance in clear cell renal cell carcinoma via USP5-mediated HIF2α deubiquitination13
Steatohepatitis alters lymphocytes cytotoxicity and localization, accelerating colorectal liver metastases13
DARPP-32 and t-DARPP in the development of resistance to anti-HER2 agents. Pre-clinical evidence from the STEP study13
Synergizing radiotherapy and immunotherapy: Current challenges and strategies for optimization12
A novel microprotein MUCP1 promotes colorectal cancer metabolic reprogramming by regulating mitochondrial succinate transport12
Corrigendum to “DNA-methylation eraser TET2 activates WTIP expression to suppress an AKT-dependent chemoresistance of gastric cancer” [Neoplasia volume 2025 Apr 24:65:101166]12
Comprehensive profiling of EGFR mutation subtypes reveals genomic-clinical associations in non-small-cell lung cancer patients on first-generation EGFR inhibitors12
Molecular landscape and clinical translation of DNA damage response alterations in solid tumors: A pan-cancer perspective on precision oncology12
SMARCA4 deficiency in glioblastoma: Mitochondrial transfer from MSCs and the clinical dilemma in targeting the tumor microenvironment12
Activation of PERK/eIF2α/ATF4 signaling inhibits ERα expression in breast cancer12
Differential prognostic association of systemic inflammatory biomarkers on survival outcomes in head and neck squamous cell carcinoma patients by human papillomavirus status12
ΔNp63 silencing, DNA methylation shifts, and epithelial-mesenchymal transition resulted from TAp63 genome editing in squamous cell carcinoma12
Phase I clinical trial of a novel procaspase-3 activator SM-1 with temozolomide in recurrent high-grade gliomas12
Regulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells after treatment with dutasteride and lovastatin12
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