Molecular Cancer

(The TQCC of Molecular Cancer is 151. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Role of hypoxia in cancer therapy by regulating the tumor microenvironment677
Targeting PI3K in cancer: mechanisms and advances in clinical trials626
Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance539
Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4518
Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape503
The role of m6A RNA methylation in human cancer479
Functions of N6-methyladenosine and its role in cancer474
Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway409
The role of necroptosis in cancer biology and therapy388
METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma357
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner318
The novel roles of circRNAs in human cancer312
Emerging roles of lipid metabolism in cancer metastasis302
CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer302
Exosomal circRNAs: biogenesis, effect and application in human diseases297
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3294
Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis293
METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer261
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1261
Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3261
Neoantigen vaccine: an emerging tumor immunotherapy260
A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling242
Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance242
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT240
A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis236
Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment232
Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression226
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer215
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer215
METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST215
RETRACTED ARTICLE: The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression210
m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1208
Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkers205
Effects of exosomes on pre-metastatic niche formation in tumors205
Exosomes in the tumor microenvironment as mediators of cancer therapy resistance204
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance200
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3195
Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis193
Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review191
Molecular characterization and clinical relevance of m6A regulators across 33 cancer types189
AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications186
RETRACTED ARTICLE: Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer184
Mechanisms associated with biogenesis of exosomes in cancer179
The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma178
Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression175
Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN175
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression170
Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities167
The relationship between autophagy and the immune system and its applications for tumor immunotherapy161
MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer160
Extracellular vesicles in the tumor microenvironment: old stories, but new tales156
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment156
Circular RNA 100146 functions as an oncogene through direct binding to miR-361-3p and miR-615-5p in non-small cell lung cancer154
The role of exosomal PD-L1 in tumor progression and immunotherapy153
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma151