Molecular Cancer

Papers
(The median citation count of Molecular Cancer is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Correction to: The function and mechanisms of action of circular RNAs in Urologic Cancer1376
LMTK3 regulation of EV biogenesis and cargo sorting promotes tumour growth by reducing monocyte infiltration and driving pro-tumourigenic macrophage polarisation in breast cancer1072
Spatial and functional dissection of cancer-associated fibroblasts-mediated immune modulation in H. pylori-associated gastric cancer1060
Development and validation of a small extracellular vesicle-derived RNA signature for early diagnosis of lung adenocarcinoma and prognosis in advanced stages823
BRD9-p53-E2F1 circuit orchestrates cell growth and DNA damage repair in gastric cancer788
Immunotherapies in rare cancers786
CRISPR based therapeutics: a new paradigm in cancer precision medicine676
Chaperone-mediated autophagy modulates Snail protein stability: implications for breast cancer metastasis664
Correction: m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2–mediated YAP activity in NSCLC649
Neoadjuvant immunotherapy in squamous cell carcinoma of the head and neck: current evidence and future perspectives638
The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p/CARM1 axis626
The CD47/TSP-1 axis: a promising avenue for ovarian cancer treatment and biomarker research575
E3 ubiquitin ligase MAGI3 degrades c-Myc and acts as a predictor for chemotherapy response in colorectal cancer563
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers495
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments447
Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells415
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma413
TGF-β signaling promotes cervical cancer metastasis via CDR1as349
Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma343
Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatment331
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway327
Advances in RNA-based cancer therapeutics: pre-clinical and clinical implications319
Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers304
The miR-23a/27a/24 − 2 cluster drives immune evasion and resistance to PD-1/PD-L1 blockade in non-small cell lung cancer302
The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers288
circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis276
Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy273
LINC02159 promotes non-small cell lung cancer progression via ALYREF/YAP1 signaling262
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression255
ERK mediates interferon gamma-induced melanoma cell death254
EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3248
Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery246
Exosomal circSIPA1L3-mediated intercellular communication contributes to glucose metabolic reprogramming and progression of triple negative breast cancer240
Correction: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis239
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state234
Efferocytosis: the art of cellular clearance and novel perspectives in disease therapy216
KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis212
Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells210
PIK3CA mutations-mediated downregulation of circLHFPL2 inhibits colorectal cancer progression via upregulating PTEN205
LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling202
Correction: YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment201
Biomolecular phase separation in tumorigenesis: from aberrant condensates to therapeutic vulnerabilities198
Increased plasma concentrations of acyl-coenzyme A binding protein (ACBP) predict future lung cancer development in smokers at risk of cardiovascular disease192
Biofilm formation by the host microbiota: a protective shield against immunity and its implication in cancer191
Nuclear receptors as novel regulators that modulate cancer radiosensitivity and normal tissue radiotoxicity190
Emerging roles of tRNA-derived fragments in cancer177
Bidirectional role of neutrophils in tumor development177
Effects of RNA methylation on Tumor angiogenesis and cancer progression175
Nanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing174
Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer172
Letter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection171
Gold nanoparticles and gold nanorods in the landscape of cancer therapy170
Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes170
NK cells are never alone: crosstalk and communication in tumour microenvironments167
Tumor cell-intrinsic MELK enhanced CCL2-dependent immunosuppression to exacerbate hepatocarcinogenesis and confer resistance of HCC to radiotherapy166
Nanomedicine in Cancer Therapeutics: Current Perspectives from Bench to Bedside164
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments163
Insights into N6-methyladenosine and programmed cell death in cancer162
Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation162
Dissecting small cell carcinoma of the esophagus ecosystem by single-cell transcriptomic analysis161
Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer161
Correction: CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling156
Retraction Note: Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis156
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer155
Tumor-associated macrophages: untapped molecular targets to improve T cell-based immunotherapy155
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance153
A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer150
lncRNAs: the unexpected link between protein synthesis and cancer adaptation150
Circular RNA circCLASP2 promotes nasopharyngeal carcinoma progression through binding to DHX9 to enhance PCMT1 translation148
Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition147
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11147
Biologically targeted dual adaptive and innate nano-Immunotherapy for clear cell renal cell carcinoma treatment146
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy143
Correction: Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis141
Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies140
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors138
Targeting HNRNPU to overcome cisplatin resistance in bladder cancer137
Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells137
The application of organoids in treatment decision-making for digestive system cancers: progress and challenges137
m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma135
Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma134
Correction: Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT1133
DLL3-guided therapies in small-cell lung cancer: from antibody-drug conjugate to precision immunotherapy and radioimmunotherapy133
Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer128
Neuroscience of cancer: unraveling the complex interplay between the nervous system, the tumor and the tumor immune microenvironment127
Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing127
Molecular mechanisms of tumor resistance to radiotherapy127
Context-dependent impact of type I interferon signaling in cancer125
Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression124
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring124
A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression123
EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?122
Activation-induced cytidine deaminase causes recurrent splicing mutations in diffuse large B-cell lymphoma122
Correction: MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer122
Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma121
Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age120
Targeting metastasis in paediatric bone sarcomas120
Size matters: integrating tumour volume and immune activation signatures predicts immunotherapy response118
N-glycosylation of PD-L1 modulates the efficacy of immune checkpoint blockades targeting PD-L1 and PD-1118
A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions116
CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma116
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients115
Cancer neuroscience in head and neck: interactions, modulation, and therapeutic strategies115
CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling114
Co-transcriptional R-loops-mediated epigenetic regulation drives growth retardation and docetaxel chemosensitivity enhancement in advanced prostate cancer113
Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy112
A positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasis112
Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response112
An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer111
Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond110
Metabolic checkpoints in immune cell reprogramming: rewiring immunometabolism for cancer therapy110
Inhibition of 6-phosphogluconate dehydrogenase suppresses esophageal squamous cell carcinoma growth and enhances the anti-tumor effects of metformin via the AMPK/mTOR pathway110
A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma109
BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors106
The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin106
Harnessing the MYB-dependent TAL1 5’super-enhancer for targeted therapy in T-ALL106
Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA103
Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges102
Correction: Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy101
CircNFIB inhibits tumor growth and metastasis through suppressing MEK1/ERK signaling in intrahepatic cholangiocarcinoma100
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway99
Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway98
Retraction Note: Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer98
PD1/PD-L1 blockade in clear cell renal cell carcinoma: mechanistic insights, clinical efficacy, and future perspectives98
Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells96
Biological and pharmacological roles of m6A modifications in cancer drug resistance96
Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer95
Role of a novel circRNA-CGNL1 in regulating pancreatic cancer progression via NUDT4–HDAC4–RUNX2–GAMT-mediated apoptosis95
A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better93
PRMT7: a survive-or-die switch in cancer stem cells93
A high proportion of germline variants in pediatric chronic myeloid leukemia93
DNA methylation-associated dysregulation of transfer RNA expression in human cancer92
CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals91
CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis91
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine91
BIRC2 blockade facilitates immunotherapy of hepatocellular carcinoma90
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination89
Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT189
Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis89
Anti irradiation nanoparticles shelter immune organ from radio-damage via preventing the IKK/IκB/NF-κB activation88
Exosomal miR-4745-5p/3911 from N2-polarized tumor-associated neutrophils promotes gastric cancer metastasis by regulating SLIT288
Spatiotemporal metabolomic approaches to the cancer-immunity panorama: a methodological perspective87
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling87
Inflammation in cancer: therapeutic opportunities from new insights86
Identification of HSP90B1 in pan-cancer hallmarks to aid development of a potential therapeutic target85
Epithelial-to-mesenchymal transition (EMT) and cancer metastasis: the status quo of methods and experimental models 202585
Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment84
Glioma targeted therapy: insight into future of molecular approaches83
Correction: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression82
Correction: Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance81
Pangaea Oncology, Dexeus University Hospital: bridging preclinical and clinical research81
Shifting landscapes of gender equity in oncology journals: a decade of authorship trends79
Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network79
SELP+ TEC:CD8+ T cell crosstalk associates with improved radiotherapy efficacy in cervical cancer78
Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors78
Exploring molecular and cellular mechanisms of Pre-Metastatic niche in renal cell carcinoma78
Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers78
Retraction Note to: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis78
CircHERC1 promotes non-small cell lung cancer cell progression by sequestering FOXO1 in the cytoplasm and regulating the miR-142-3p-HMGB1 axis77
Microbiome-targeted nanoplatforms and engineering approaches in breast cancer therapy77
Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the ERK signaling pathway77
Proteomics technologies for cancer liquid biopsies77
Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency76
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development76
Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma76
Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment75
Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy75
Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy75
Overcoming resistance to anti-PD-L1 immunotherapy: mechanisms, combination strategies, and future directions74
Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway74
YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment74
Exploiting innate immunity for cancer immunotherapy74
An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer74
A comprehensive overview of ovarian cancer stem cells: correlation with high recurrence rate, underlying mechanisms, and therapeutic opportunities74
Targeting TGF-β signal transduction for fibrosis and cancer therapy71
Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells70
The role of m6A RNA methylation in cancer metabolism69
Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis69
Immune dynamics shaping pre-metastatic and metastatic niches in liver metastases: from molecular mechanisms to therapeutic strategies69
CircRNA aptamer targets IGF2BP2 to overcome acquired BETi resistance68
Correction: The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin68
Combined proteomics and CRISPR‒Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo68
Retraction Note: Quercetin-induced miR-200b-3p regulates the mode of self-renewing divisions in pancreatic cancer68
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations67
Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers67
Clustering cancers by shared transcriptional risk reveals novel targets for cancer therapy67
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma67
Hijacking of the nervous system in cancer: mechanism and therapeutic targets67
A prospective multi-cohort study identifies and validates a 5-gene peripheral blood signature predictive of immunotherapy response in non-small cell lung cancer67
The application of organoids in investigating immune evasion in the microenvironment of gastric cancer and screening novel drug candidates67
Circulating cell-free DNA methylation patterns as non-invasive biomarkers to monitor colorectal cancer treatment efficacy without referencing primary site mutation profiles66
Expression of mTOR in normal and pathological conditions66
Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T66
Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells65
c-Rel drives pancreatic cancer metastasis through fibronectin-integrin signaling-induced isolation stress resistance and EMT65
Next-generation CAR-T cells design: leveraging tumor features for enhanced efficacy64
Targeting m7G-enriched circKDM1A prevents colorectal cancer progression64
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia63
Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translation62
The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression62
The University of Kansas Cancer Center (KUCC), an NCI designated comprehensive cancer center61
Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches61
Correction: CMTM6 overexpression confers trastuzumab resistance in HER2‑positive breast cancer61
Mapping cancer biology in space: applications and perspectives on spatial omics for oncology61
Extracellular vesicles in tumor immunity: mechanisms and novel insights61
Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells61
LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer61
Correction: circCYP24A1 facilitates esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB-induced CCL5 secretion60
Correction: ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH60
Correction: Comprehensive review of CRISPR‑based gene editing: mechanisms, challenges, and applications in cancer therapy59
Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer59
Deciphering the role of LGALS2: insights into tertiary lymphoid structure-associated dendritic cell activation and immunotherapeutic potential in breast cancer patients59
circRNAs shed light on cancer diagnosis and treatment58
Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma58
A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer58
Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop57
Traditional Chinese medicine in the treatment of breast Cancer57
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity57
Evolution of direct RAS inhibitors: from undruggable target to clinical breakthroughs57
Lipid reprogramming and ferroptosis crosstalk in clear cell renal cell carcinoma: metabolic vulnerabilities and therapeutic targeting57
Downregulation of Sod2 increases atypical flat lesions and dysplasia to advance pancreatic ductal adenocarcinoma57
Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations57
Transfer RNA-derived small RNAs in tumor microenvironment55
The epigenetic hallmarks of immune cells in cancer55
Splicing factor derived circular RNA circCAMSAP1 accelerates nasopharyngeal carcinoma tumorigenesis via a SERPINH1/c-Myc positive feedback loop55
BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion55
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy54
CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL254
HPGD induces ferroptosis and autophagy to suppress esophageal squamous cell carcinoma through the LXA4–ERK1/2–U2AF2–TFRC axis54
Writers, readers, and erasers RNA modifications and drug resistance in cancer54
circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX454
PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy54
Mechanisms and cross-talk of regulated cell death and their epigenetic modifications in tumor progression53
Advances in immunotherapy for triple-negative breast cancer53
The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy53
​​The immune microenvironment of pathogen-associated cancers and current clinical therapeutics53
The mycobiome in human cancer: analytical challenges, molecular mechanisms, and therapeutic implications52
The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer52
RAF inhibitor re-challenge therapy in BRAF-aberrant pan-cancers: the RE-RAFFLE study52
The journey of CAR-T therapy in hematological malignancies52
CAR T cells: engineered immune cells to treat brain cancers and beyond52
Clinical application of liquid biopsy in colorectal cancer: detection, prediction, and treatment monitoring52
Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy51
Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug51
Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study51
Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer51
The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells51
Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma50
Distant origin of glioblastoma recurrence: neural stem cells in the subventricular zone serve as a source of tumor reconstruction after primary resection50
Nanoparticles and bone microenvironment: a comprehensive review for malignant bone tumor diagnosis and treatment50
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