OOIR: Observatory of International Research

Papers

(The H4-Index of Cancer Cell International is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment	279
New insights into M1/M2 macrophages: key modulators in cancer progression	187
Challenges of applying multicellular tumor spheroids in preclinical phase	157
p53 signaling in cancer progression and therapy	148
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment	134
Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine	130
circRNA-miRNA-mRNA regulatory network in human lung cancer: an update	126
The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review	122
Clinical applications of artificial intelligence and machine learning in cancer diagnosis: looking into the future	112
The anti-cancer effects of fucoidan: a review of both in vivo and in vitro investigations	103
The biological function of m6A demethylase ALKBH5 and its role in human disease	100
The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers	85
Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier	80
RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer	73
Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer	68
Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk	68
Polyamines and related signaling pathways in cancer	65
Overexpression of kinesin superfamily members as prognostic biomarkers of breast cancer	65
Prognostic value of systemic immune-inflammation index in patients with urologic cancers: a meta-analysis	63
Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets	63
Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma	61
CircRNA CDR1as/miR-641/HOXA9 pathway regulated stemness contributes to cisplatin resistance in non-small cell lung cancer (NSCLC)	60
Emerging roles of RNA methylation in gastrointestinal cancers	59
Dynamic regulation and functions of mRNA m6A modification	58
FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport	55

Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review	55
CircUBE2D2 (hsa_circ_0005728) promotes cell proliferation, metastasis and chemoresistance in triple-negative breast cancer by regulating miR-512-3p/CDCA3 axis	54
RETRACTED ARTICLE: Circ_0008035 contributes to cell proliferation and inhibits apoptosis and ferroptosis in gastric cancer via miR-599/EIF4A1 axis	53
METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m6A modification	52
SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway	51
Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway	51
Characterization of a ferroptosis and iron-metabolism related lncRNA signature in lung adenocarcinoma	50
A robust twelve-gene signature for prognosis prediction of hepatocellular carcinoma	50
Recent advances and limitations of mTOR inhibitors in the treatment of cancer	50
Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in colorectal cancer	50
Prognostic value of the systemic immune-inflammation index in patients with breast cancer: a meta-analysis	50
LncRNA KCNQ1OT1 sponges miR-15a to promote immune evasion and malignant progression of prostate cancer via up-regulating PD-L1	49
Serum-derived three-circRNA signature as a diagnostic biomarker for hepatocellular carcinoma	49
Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC	48
The yin and yang functions of extracellular ATP and adenosine in tumor immunity	47
Induction and application of ferroptosis in cancer therapy	47
Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1	47
Significance of tumor mutation burden combined with immune infiltrates in the progression and prognosis of ovarian cancer	46
Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatment	46
Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis	45
Cancer-associated fibroblasts and resistance to anticancer therapies: status, mechanisms, and countermeasures	45
Myricetin: targeting signaling networks in cancer and its implication in chemotherapy	45
Hexokinase inhibition using D-Mannoheptulose enhances oncolytic newcastle disease virus-mediated killing of breast cancer cells	45
Exosome-transferred hsa_circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the miR-520a-5p/CDK4 pathway	45