OOIR: Observatory of International Research

Papers

(The H4-Index of Aging Cell is 50. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells	252
Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training	175
Alpha‐ketoglutarate ameliorates age‐related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF‐κB signaling	154
Advanced age and female sex protect cerebral arteries from mitochondrial depolarization and apoptosis during acute oxidative stress	149
Additional Cover	138
Issue Information	109
Featured Cover	101
Aging Adipose‐Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA‐DR	100
Cooperative effects of SIRT1 and SIRT2 on APP acetylation	98
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice	96
Expression of mitochondrial oxidative stress response genes in muscle is associated with mitochondrial respiration, physical performance, and muscle mass in the Study of Muscle, Mobility, and Aging	91
Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial	89
Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging	87
Diminished and Altered Cellular Senescence Response in Delayed Wound Healing of Aging	85
Featured Cover	85
Serum‐Derived Extracellular Vesicles as Biological Indicator of Mobility Resilience in Older Adults	82
Single‐Cell Profiling Reveals Distinct Immune Communication Networks in Centenarians and Elderly Controls	81
A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo	81
Correlates of life course physical activity in participants of the Baltimore longitudinal study of aging	77
Age‐dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging	71
Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia	70
SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation	69
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain	65
The Roles of EDA2R in Ageing and Disease	63
Role of autophagy in aging: The good, the bad, and the ugly	62

Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation	61
Long‐term Tai Chi practice in older adults is associated with “younger” functional abilities	61
Nanocarriers for natural polyphenol senotherapeutics	61
Lactate Secretion by Monocytes as a Determinant of Innate Immune Cell Fitness in Healthy Elderly	60
Circadian regulation in aging: Implications for spaceflight and life on earth	60
Single Cell Sequencing Identifies Distinct Cellular Alterations in Impaired Aged and Diabetic Wounds	59
Telomere Position Effect‐Over Long Distances Acts as a Genome‐Wide Epigenetic Regulator Through a Common Alu Element	59
Associations of combined accelerated biological aging and genetic susceptibility with incidence of heart failure in a population‐based cohort study	58
Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment	58
Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic ma	58
Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging	57
Longitudinal Testing of Exploratory Behaviour in Mice Reveals Stable Cognitive Traits Across the Adult Lifespan	56
Silencing of the Metabolic Gene HKDC1 Is Associated With Aging and Neurodegeneration in Mice and Humans	56
Inflammatory and immune markers in HIV ‐infected older adults on long‐term antiretroviral therapy: Persistent elevation of s	55
Biologically Younger Individuals, as Identified by MARK ‐ AGE Biological Age Scores, Display a Dis	55
Effects of Aging on Glucose and Lipid Metabolism in Mice	54
Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in LG/J Mice	53
Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype	53
Cockayne syndrome B protein is implicated in transcription and associated chromatin dynamics in homeostatic and genotoxic conditions	53
Dysregulated nicotinamide adenine dinucleotide metabolome in patients hospitalized with COVID‐19	52
Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity	52
3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex	52
Intestinal stem cell aging at single‐cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics	51
Corrigendum to: Wnt/β‐catenin/ RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction	51
Additional Cover	50
Anatomical Society Research Studentships 2023/24	50