Nature Reviews Cancer

Article	Citations
Linking pancreatic renewal and cancer initiation	1419
Computing brain metastasis impact	1198
Digging for treasures in the tumour interactome	998
INVADEseq to study the intratumoural microbiota at host single-cell resolution	869
An inhospitable site	528
Fructose takes a detour to feed cancer	517
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment	487
Emerging strategies to investigate the biology of early cancer	451
Combinatorial strategies to target RAS-driven cancers	422
Artificial intelligence in cancer research, diagnosis and therapy	385
Oncofetal reprogramming in tumour development and progression	379
Mapping the prostate cell family tree	338
How medical anthropology can contribute to cancer research	320
Tertiary lymphoid structures as hubs of antitumour immunity	319
Author Correction: Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma	301
Connie J. Eaves (1944–2024)	281
Antihistamines boost immunotherapy	274
The recruitment of metastasis-associated monocytes	274
Fighting cancer with fat	267
Translating premalignant biology to accelerate non-small-cell lung cancer interception	253
Reply to ‘Heterogeneity of TP53 mutations necessitates differentiation with p53-rescue therapies’	252
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel	248
Targeting transcription cycles in cancer	246
Context-dependent functions of pattern recognition receptors in cancer	227
The role of CRAF in cancer progression: from molecular mechanisms to precision therapies	225

Epithelial and stromal co-evolution and complicity in pancreatic cancer	222
No mutation, tumour initiation	217
Impersonating neurons	217
Under pressure	211
Nanoreceptors take down mutant p53	204
Measuring HLA disruption using MHC Hammer	202
Tumour EVPs disrupt liver function	198
Gut microbes produce novel genotoxic metabolites	198
Dendritic cells rise and shine	196
Removing barriers to address sex differences in anticancer drug toxicity	183
Persistence is key	174
Thelpers? More like Ttroublemakers	164
Defining a ‘cells to society’ research framework for appendiceal tumours	161
Remodelling of the tumour microenvironment by the kallikrein-related peptidases	160
Tumour–host interactions through the lens of Drosophila	159
Cancer stem cell–immune cell crosstalk in tumour progression	158
3D bioprinted cancer models: from basic biology to drug development	157
Moonlighting functions of glucose metabolic enzymes and metabolites in cancer	156
Natural killer cells in antitumour adoptive cell immunotherapy	152
How chemokines organize the tumour microenvironment	151
Points of entry for tumour-infiltrating lymphocytes	150
B-ring sterols to the rescue	144
Bone voyage: immune crosstalk sets sail	141
Identifying spatial cellular structures with SPACE-GM	141
Visualizing intratumoural heterogeneity with EpicMIBI	140
In-depth organoid profiling of pancreatic cancer	140
Metabolic interplays between the tumour and the host shape the tumour macroenvironment	133
Un-Fair Skin: racial disparities in acral melanoma research	131
Leveraging the replication stress response to optimize cancer therapy	125
The path to leptomeningeal metastasis	125
Linking cell mechanical memory and cancer metastasis	122
The plasticity of mRNA translation during cancer progression and therapy resistance	118
Dynamics and specificities of T cells in cancer immunotherapy	116
In situ decellularization of tissues to resolve the tumour-associated matrix	115
Deciphering the cancer genome and epigenome	112
Understanding and addressing race disparities in childhood cancer outcomes	110
Encoding spatial tumour dynamics with Starfysh	101
Taming TAMs in brain metastases	98
The link between vitamin D and prostate cancer	97
Race influences the tumour microbiome	97
Targeted protein degradation for cancer therapy	94
Polygenic scores in cancer	90
Cancer nanomedicine	86
Don’t blame the messenger: lessons learned for cancer mRNA vaccines during the COVID-19 pandemic	85
RNA splicing dysregulation and the hallmarks of cancer	84
Acetyl-CoA metabolism in cancer	84
Z-nucleic acids give immunotherapy a boost	83
Author Correction: Antibody-based proteomics: fast-tracking molecular diagnostics in oncology	81
Local CAR manufacturing	81
Parity modulates epithelial–immune cell communication	80

Defining precancer: a grand challenge for the cancer community	79
Right ON target: a new RAS-GTP inhibitor	79
A trojan horse to target spliceosome mutant cells	77
NOTUM-mediated stem cell competition in CRC	77
Prime editing GEMMs to model cancer mutations	76
Androgen receptor signalling in non-prostatic malignancies: challenges and opportunities	74
Chromothripsis in cancer	74
Integrative medicine in oncology: redefining the standard of care	73
Targeting ferroptosis as a vulnerability in cancer	71
Tertiary lymphoid structures in anticancer immunity	71
Starting a new job	69
Neutrophils: a roadblock for immunotherapy	68
Quantum probes in cancer research	68
Functional lineage tracing to study the clonal evolution of therapy resistance	68
Glycogen condensates drive tumorigenesis by trapping Hippo kinases	68
In vivo labelling system to study cell neighbourhoods	65
Revealing genomic secrets of archival FFPE samples	63
Judith Campisi (1948–2024)	62
Inferring cancer metabolism from gene-expression data	60
New pathogen on the block	60
The present and future of the Cancer Dependency Map	58
Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data	55
Recent advances in therapeutic cancer vaccines	55
Immune-checkpoint inhibitor-mediated myocarditis: CTLA4, PD1 and LAG3 in the heart	53
Cell states can give tumorigenesis a head start	53
Carcinogenesis at single-cell resolution	53
Bidirectional CART.BiTE cells bring new hope	52
Microbiota links to immunotherapy toxicity	52
Patient-derived organoids unveil sarcoma vulnerabilities	51
Evolution and progression of Barrett’s oesophagus to oesophageal cancer	45
Global post-mortem tissue donation programmes to accelerate cancer research	45
Developing dietary interventions as therapy for cancer	44
Transfer RNAs as dynamic and critical regulators of cancer progression	44
A timeline of tumour-associated macrophage biology	41
Epigenomic heterogeneity as a source of tumour evolution	39
Traject3d for studying 3D cellular heterogeneity	39
We cannot ignore the cancer risks of wildfires	37
Author Correction: Integrative medicine in oncology: redefining the standard of care	37
Harnessing the influenza virus to fight cancer	35
Targeting cancer cell dormancy	33
Digitally enhanced Raman spectroscopy	32
Tissue clearing to examine tumour complexity in three dimensions	32
Fcγ receptors and immunomodulatory antibodies in cancer	31
Structural variations in cancer and the 3D genome	30
Guardrails for the use of generalist AI in cancer care	29
mRNA-based cancer therapeutics	28
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity	28
The role of ROS in tumour development and progression	28
The immunological and metabolic landscape in primary and metastatic liver cancer	25
Integrating microbiomics in cancer management	24
CAFs promote CRPC	23
Frozen silicified vaccines	23
AACR 2024	23
Ethnically diverse cancer cell lines for drug testing	22
EMT in chemoresistance	21
Decoding the functional impact of the cancer genome through protein–protein interactions	21
Male melanoma comes of age	21
Next-generation epidemiologic cohorts for cancer aetiology	20
Modelling and deciphering tumour metabolism in CRISPR screens	19
Mechanisms driving the immunoregulatory function of cancer cells	18
The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment	17
Fungi in cancer: not such a ‘fun-guy’	16
Advances in cutaneous squamous cell carcinoma	16
Inflammatory neutrophils	15
Silent mutations make noise	15
Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ	13
Deep tissue imaging of cancer in the infrared	13
Key role for microbiota in gut–bone crosstalk	13
Stabilizing the mood of tumours	13
Stemness in solid malignancies: coping with immune attack	12
Advances in translational research of the rare cancer type adrenocortical carcinoma	12
Decoding the basis of histological variation in human cancer	12
Disconnecting multicellular networks in brain tumours	12
Therapeutic resistance to anti-oestrogen therapy in breast cancer	12
Multiomics-guided cellular immunotherapies	12
Enhanced transposable elements	11
Glioblastomas remodel neural circuits	11
Air pollution promotes tumorigenesis through pre-existing oncogenic mutations	11
Exploiting senescence for the treatment of cancer	11
Mapping out mitochondria	10

Black voices in cancer research and oncology	9
Big data in basic and translational cancer research	9
Too much of a good thing	9
Limiting bias in AI models for improved and equitable cancer care	9
Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection	8
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment	8
Androgen receptor activation for breast cancer therapy	8
Targeting sex steroid biosynthesis for breast and prostate cancer therapy	8
Pathogenesis of cancers derived from thyroid follicular cells	7
Addressing the gaps in cancer screening for LGBTQ+ individuals	7
Fungi in cancer	6
Aristolochic acid-associated cancers: a public health risk in need of global action	6
Overcoming heterogeneity with 3D whole-tumour sampling	6
Nucleotide metabolism: a pan-cancer metabolic dependency	6
Hubs of transcriptional activity	5
Conventional chemotherapy: millions of cures, unresolved therapeutic index	5
Proximity labelling to study chromatin interactomes	5
Intercepting gastric cancer	5
Feeding latent brain metastasis	5
Breast milk for breast cancer detection	5
Tumour avatars to model patients’ responses to immunotherapy	5
Tracing the evolutionary history of breast cancer	4
scAtlasVAE: a deep learning framework for generating a human CD8+ T cell atlas	4
Understanding tumour endothelial cell heterogeneity and function from single-cell omics	4
Epigenetic memory	4
VIBRANT: mapping cell phenotypes using vibrational spectroscopy	4
Small speckles, big impact	4
Defining and using immune archetypes to classify and treat cancer	4
Obesity as a promoter in BRCA mutation carriers	4
The fibroinflammatory response in cancer	4
Towards cancer equity via patient outreach	4
Polyamines in cancer: integrating organismal metabolism and antitumour immunity	4
Metabolic mechanisms of medulloblastoma metastasis	4
A machine learning toolkit for subtyping cancer in existing and new datasets	3
Targeting the DNA damage response in immuno-oncology: developments and opportunities	3
The dynamic role of platelets in cancer progression and their therapeutic implications	3
Taking the path of most resistance	3
Enhancing cellular immunotherapies in cancer by engineering selective therapeutic resistance	3
Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma	3
Lymphatic vessels in the age of cancer immunotherapy	3
Protection against tumour formation	3
Multiplex protein imaging in tumour biology	3
Bringing community to our pages	3
Studying extrachromosomal DNA with the ecTag method	3
Exploiting temporal aspects of cancer immunotherapy	3
Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment	3
Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications	3
Sex affects cancer genomes	3
Pressing defence	2
Shared immunosuppressive mechanism between pregnancy and cancer	2
How protons pave the way to aggressive cancers	2
Naughty neutrophils	2
Taking a detour	2
Epigenetic lesions drive gliomagenesis	2
Harnessing multimodal data integration to advance precision oncology	2
Lactate gives a sour taste	2
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention	2
Expanding oesophageal cancer research and care in eastern Africa	2
Preprints as tools to advance careers	2
NET-working under stress	2
The BMP pathway could curb cachexia	2
Non-coding driver mutations in human cancer	2
In Polϴ position	2
Cancer’s sensory experience	2
Hidden epithelial subtypes refine colorectal cancer classification	2
Ageing lipids map melanoma’s journey	2
Presenting fibroblasts	2
Oncologists must act to manage cancer detected through prenatal screening	2
Managing cancer following the World Trade Center disaster	2
Antidepressants revive T cells	2
Allies in the epidermis	2
Targeting the tumour’s little helpers	2
Mastering the use of cellular barcoding to explore cancer heterogeneity	2
Targeting aberrant splicing	2
Stromal cells drive tumorigenesis in BRCA1 mutation carriers	2
PDX models for functional precision oncology and discovery science	2
Phosphoinositide kinases in cancer: from molecular mechanisms to therapeutic opportunities	2
Rusting away with age	2
Liquid biopsies for Hodgkin lymphoma	2
Author Correction: The importance of 3D fibre architecture in cancer and implications for biomaterial model design	2