Nature Reviews Cancer

Article	Citations
Linking pancreatic renewal and cancer initiation	1366
Computing brain metastasis impact	1153
Digging for treasures in the tumour interactome	961
INVADEseq to study the intratumoural microbiota at host single-cell resolution	848
An inhospitable site	509
Fructose takes a detour to feed cancer	501
Emerging strategies to investigate the biology of early cancer	467
Artificial intelligence in cancer research, diagnosis and therapy	453
Combinatorial strategies to target RAS-driven cancers	428
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment	407
Oncofetal reprogramming in tumour development and progression	370
Mapping the prostate cell family tree	369
How medical anthropology can contribute to cancer research	324
Tertiary lymphoid structures as hubs of antitumour immunity	312
Author Correction: Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma	306
Connie J. Eaves (1944–2024)	286
The recruitment of metastasis-associated monocytes	280
Antihistamines boost immunotherapy	271
Fighting cancer with fat	264
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel	259
Translating premalignant biology to accelerate non-small-cell lung cancer interception	252
Epithelial and stromal co-evolution and complicity in pancreatic cancer	248
The role of CRAF in cancer progression: from molecular mechanisms to precision therapies	246
Targeting transcription cycles in cancer	240
Context-dependent functions of pattern recognition receptors in cancer	235

No mutation, tumour initiation	218
Impersonating neurons	216
Under pressure	214
Nanoreceptors take down mutant p53	213
Moonlighting functions of glucose metabolic enzymes and metabolites in cancer	208
Defining a ‘cells to society’ research framework for appendiceal tumours	200
Measuring HLA disruption using MHC Hammer	198
Remodelling of the tumour microenvironment by the kallikrein-related peptidases	194
Gut microbes produce novel genotoxic metabolites	191
Tumour EVPs disrupt liver function	187
Dendritic cells rise and shine	185
Removing barriers to address sex differences in anticancer drug toxicity	179
Persistence is key	172
Thelpers? More like Ttroublemakers	171
Tumour–host interactions through the lens of Drosophila	160
Natural killer cells in antitumour adoptive cell immunotherapy	155
3D bioprinted cancer models: from basic biology to drug development	149
How chemokines organize the tumour microenvironment	148
Cancer stem cell–immune cell crosstalk in tumour progression	148
B-ring sterols to the rescue	145
Points of entry for tumour-infiltrating lymphocytes	145
In-depth organoid profiling of pancreatic cancer	144
Identifying spatial cellular structures with SPACE-GM	144
Bone voyage: immune crosstalk sets sail	144
Visualizing intratumoural heterogeneity with EpicMIBI	140
Leveraging the replication stress response to optimize cancer therapy	135
Un-Fair Skin: racial disparities in acral melanoma research	134
Metabolic interplays between the tumour and the host shape the tumour macroenvironment	133
The path to leptomeningeal metastasis	132
Linking cell mechanical memory and cancer metastasis	131
Dynamics and specificities of T cells in cancer immunotherapy	128
The plasticity of mRNA translation during cancer progression and therapy resistance	120
In situ decellularization of tissues to resolve the tumour-associated matrix	119
Deciphering the cancer genome and epigenome	112
Encoding spatial tumour dynamics with Starfysh	111
Understanding and addressing race disparities in childhood cancer outcomes	111
Taming TAMs in brain metastases	108
The link between vitamin D and prostate cancer	106
Race influences the tumour microbiome	106
Don’t blame the messenger: lessons learned for cancer mRNA vaccines during the COVID-19 pandemic	101
Targeted protein degradation for cancer therapy	97
Polygenic scores in cancer	95
Acetyl-CoA metabolism in cancer	94
RNA splicing dysregulation and the hallmarks of cancer	92
Cancer nanomedicine	88
Z-nucleic acids give immunotherapy a boost	87
Local CAR manufacturing	86
Parity modulates epithelial–immune cell communication	82
Author Correction: Antibody-based proteomics: fast-tracking molecular diagnostics in oncology	82
Right ON target: a new RAS-GTP inhibitor	80

Integrative medicine in oncology: redefining the standard of care	80
A trojan horse to target spliceosome mutant cells	79
Prime editing GEMMs to model cancer mutations	76
Chromothripsis in cancer	76
Defining precancer: a grand challenge for the cancer community	74
Tertiary lymphoid structures in anticancer immunity	73
Androgen receptor signalling in non-prostatic malignancies: challenges and opportunities	73
Targeting ferroptosis as a vulnerability in cancer	71
Starting a new job	70
Glycogen condensates drive tumorigenesis by trapping Hippo kinases	69
Quantum probes in cancer research	66
Functional lineage tracing to study the clonal evolution of therapy resistance	65
Neutrophils: a roadblock for immunotherapy	65
In vivo labelling system to study cell neighbourhoods	64
Revealing genomic secrets of archival FFPE samples	64
Judith Campisi (1948–2024)	63
New pathogen on the block	60
The present and future of the Cancer Dependency Map	60
Inferring cancer metabolism from gene-expression data	60
Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data	57
Immune-checkpoint inhibitor-mediated myocarditis: CTLA4, PD1 and LAG3 in the heart	57
Cell states can give tumorigenesis a head start	56
Carcinogenesis at single-cell resolution	56
Microbiota links to immunotherapy toxicity	55
Bidirectional CART.BiTE cells bring new hope	52
Metastases arrive at other organs via bone	52
Patient-derived organoids unveil sarcoma vulnerabilities	52
Global post-mortem tissue donation programmes to accelerate cancer research	51
Evolution and progression of Barrett’s oesophagus to oesophageal cancer	50
Epigenomic heterogeneity as a source of tumour evolution	50
Developing dietary interventions as therapy for cancer	48
Transfer RNAs as dynamic and critical regulators of cancer progression	45
A timeline of tumour-associated macrophage biology	43
Author Correction: Integrative medicine in oncology: redefining the standard of care	42
Traject3d for studying 3D cellular heterogeneity	42
We cannot ignore the cancer risks of wildfires	40
Guardrails for the use of generalist AI in cancer care	38
Harnessing the influenza virus to fight cancer	36
Structural variations in cancer and the 3D genome	34
Targeting cancer cell dormancy	34
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity	33
The immunological and metabolic landscape in primary and metastatic liver cancer	32
mRNA-based cancer therapeutics	32
The role of ROS in tumour development and progression	30
Tissue clearing to examine tumour complexity in three dimensions	30
Integrating microbiomics in cancer management	28
Frozen silicified vaccines	28
AACR 2024	28
Fcγ receptors and immunomodulatory antibodies in cancer	28
Ethnically diverse cancer cell lines for drug testing	26
CAFs promote CRPC	26
Fungi in cancer: not such a ‘fun-guy’	24
Decoding the functional impact of the cancer genome through protein–protein interactions	23
Next-generation epidemiologic cohorts for cancer aetiology	22
Male melanoma comes of age	22
EMT in chemoresistance	21
Modelling and deciphering tumour metabolism in CRISPR screens	21
Mechanisms driving the immunoregulatory function of cancer cells	20
The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment	20
Advances in cutaneous squamous cell carcinoma	19
Inflammatory neutrophils	18
Silent mutations make noise	18
Key role for microbiota in gut–bone crosstalk	17
Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ	16
Multiomics-guided cellular immunotherapies	16
Decoding the basis of histological variation in human cancer	15
Stabilizing the mood of tumours	14
Disconnecting multicellular networks in brain tumours	13
Deep tissue imaging of cancer in the infrared	13
Advances in translational research of the rare cancer type adrenocortical carcinoma	12
Stemness in solid malignancies: coping with immune attack	12
Exploiting senescence for the treatment of cancer	11
Therapeutic resistance to anti-oestrogen therapy in breast cancer	11
Mapping out mitochondria	10
Air pollution promotes tumorigenesis through pre-existing oncogenic mutations	10
Fungi in cancer	10
Enhanced transposable elements	10
Glioblastomas remodel neural circuits	10
Overcoming heterogeneity with 3D whole-tumour sampling	9
Androgen receptor activation for breast cancer therapy	9

Black voices in cancer research and oncology	9
Limiting bias in AI models for improved and equitable cancer care	9
Too much of a good thing	9
Big data in basic and translational cancer research	8
Pathogenesis of cancers derived from thyroid follicular cells	8
Aristolochic acid-associated cancers: a public health risk in need of global action	8
Nucleotide metabolism: a pan-cancer metabolic dependency	8
Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection	8
Targeting sex steroid biosynthesis for breast and prostate cancer therapy	7
Breast milk for breast cancer detection	7
Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment	7
Proximity labelling to study chromatin interactomes	7
Hubs of transcriptional activity	6
Intercepting gastric cancer	6
The fibroinflammatory response in cancer	6
Tumour avatars to model patients’ responses to immunotherapy	5
Feeding latent brain metastasis	5
Understanding tumour endothelial cell heterogeneity and function from single-cell omics	4
Epigenetic memory	4
VIBRANT: mapping cell phenotypes using vibrational spectroscopy	4
Towards cancer equity via patient outreach	4
Small speckles, big impact	4
Conventional chemotherapy: millions of cures, unresolved therapeutic index	4
Polyamines in cancer: integrating organismal metabolism and antitumour immunity	4
Obesity as a promoter in BRCA mutation carriers	4
Protection against tumour formation	4
Defining and using immune archetypes to classify and treat cancer	4
Metabolic mechanisms of medulloblastoma metastasis	4
Tracing the evolutionary history of breast cancer	4
Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications	4
Bringing community to our pages	3
A machine learning toolkit for subtyping cancer in existing and new datasets	3
Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma	3
Exploiting temporal aspects of cancer immunotherapy	3
Studying extrachromosomal DNA with the ecTag method	3
The dynamic role of platelets in cancer progression and their therapeutic implications	3
Sex affects cancer genomes	3
Lymphatic vessels in the age of cancer immunotherapy	3
Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment	3
Enhancing cellular immunotherapies in cancer by engineering selective therapeutic resistance	3
Taking the path of most resistance	3
Presenting fibroblasts	3
scAtlasVAE: a deep learning framework for generating a human CD8+ T cell atlas	3
Multiplex protein imaging in tumour biology	3
Targeting the DNA damage response in immuno-oncology: developments and opportunities	3
PDX models for functional precision oncology and discovery science	2
In Polϴ position	2
Author Correction: The importance of 3D fibre architecture in cancer and implications for biomaterial model design	2
Managing cancer following the World Trade Center disaster	2
Shared immunosuppressive mechanism between pregnancy and cancer	2
Allies in the epidermis	2
Targeting the tumour’s little helpers	2
Stromal cells drive tumorigenesis in BRCA1 mutation carriers	2
Taking a detour	2
Epigenetic lesions drive gliomagenesis	2
Harnessing multimodal data integration to advance precision oncology	2
Lactate gives a sour taste	2
Rusting away with age	2
Oncologists must act to manage cancer detected through prenatal screening	2
Liquid biopsies for Hodgkin lymphoma	2
Pressing defence	2
Naughty neutrophils	2
How protons pave the way to aggressive cancers	2
Mastering the use of cellular barcoding to explore cancer heterogeneity	2
Expanding oesophageal cancer research and care in eastern Africa	2
Phosphoinositide kinases in cancer: from molecular mechanisms to therapeutic opportunities	2
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention	2
Non-coding driver mutations in human cancer	2
Tumour hypoxia in driving genomic instability and tumour evolution	2
Making cancer research more inclusive	2
Antidepressants revive T cells	2
Preprints as tools to advance careers	2
The BMP pathway could curb cachexia	2
NET-working under stress	2
Targeting aberrant splicing	2
Cancer’s sensory experience	2
Hidden epithelial subtypes refine colorectal cancer classification	2