OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Reviews Cancer is 77. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Computing brain metastasis impact	1628
Digging for treasures in the tumour interactome	1168
Linking pancreatic renewal and cancer initiation	976
An inhospitable site	604
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment	563
Combining spatial transcriptomics and AI to enhance brain tumour diagnosis	535
INVADEseq to study the intratumoural microbiota at host single-cell resolution	401
Combinatorial strategies to target RAS-driven cancers	376
Oncofetal reprogramming in tumour development and progression	374
Fructose takes a detour to feed cancer	364
Emerging strategies to investigate the biology of early cancer	339
Implementing practice-changing progress for managing cancer of unknown primary	334
How medical anthropology can contribute to cancer research	318
Mapping the prostate cell family tree	317
Fighting cancer with fat	308
Reply to ‘Heterogeneity of TP53 mutations necessitates differentiation with p53-rescue therapies’	307
3D chromatin architecture as a predictor of somatic mutations in cancer genomes	280
Translating premalignant biology to accelerate non-small-cell lung cancer interception	265
Author Correction: Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma	262
Connie J. Eaves (1944–2024)	261
The recruitment of metastasis-associated monocytes	253
Antihistamines boost immunotherapy	248
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel	246
The role of CRAF in cancer progression: from molecular mechanisms to precision therapies	225
Epithelial and stromal co-evolution and complicity in pancreatic cancer	219

The evolution of cancer and ageing: a history of constraint	209
Tertiary lymphoid structures as hubs of antitumour immunity	200
Context-dependent functions of pattern recognition receptors in cancer	196
Targeting transcription cycles in cancer	194
Gut microbes produce novel genotoxic metabolites	193
Under pressure	188
No mutation, tumour initiation	185
Impersonating neurons	183
Nanoreceptors take down mutant p53	183
Dendritic cells rise and shine	177
Tumour EVPs disrupt liver function	177
AACR 2025	173
Measuring HLA disruption using MHC Hammer	170
Removing barriers to address sex differences in anticancer drug toxicity	164
Persistence is key	158
Defining a ‘cells to society’ research framework for appendiceal tumours	152
Thelpers? More like Ttroublemakers	146
Moonlighting functions of glucose metabolic enzymes and metabolites in cancer	144
Remodelling of the tumour microenvironment by the kallikrein-related peptidases	141
Natural killer cells in antitumour adoptive cell immunotherapy	137
3D bioprinted cancer models: from basic biology to drug development	131
Environmental endocrine disruptors: rethinking the origins of early-onset ER+ breast cancer	126
How chemokines organize the tumour microenvironment	126
Un-Fair Skin: racial disparities in acral melanoma research	121
Bone voyage: immune crosstalk sets sail	120
B-ring sterols to the rescue	118
Identifying spatial cellular structures with SPACE-GM	116
In-depth organoid profiling of pancreatic cancer	116
Visualizing intratumoural heterogeneity with EpicMIBI	115
The path to leptomeningeal metastasis	111
The immune microenvironment of colorectal cancer	111
Points of entry for tumour-infiltrating lymphocytes	111
Regulatory T cells in the tumour microenvironment	105
Leveraging the replication stress response to optimize cancer therapy	105
Linking cell mechanical memory and cancer metastasis	102
Metabolic interplays between the tumour and the host shape the tumour macroenvironment	100
In situ decellularization of tissues to resolve the tumour-associated matrix	100
Dynamics and specificities of T cells in cancer immunotherapy	100
Understanding and addressing race disparities in childhood cancer outcomes	99
Encoding spatial tumour dynamics with Starfysh	99
Race influences the tumour microbiome	98
Deciphering the cancer genome and epigenome	97
Don’t blame the messenger: lessons learned for cancer mRNA vaccines during the COVID-19 pandemic	95
The link between vitamin D and prostate cancer	95
Polygenic scores in cancer	90
Acetyl-CoA metabolism in cancer	86
RNA splicing dysregulation and the hallmarks of cancer	82
Taming TAMs in brain metastases	81
Cancer nanomedicine	81
Targeted protein degradation for cancer therapy	80

Local CAR manufacturing	77
Z-nucleic acids give immunotherapy a boost	77