Nature Reviews Immunology

Papers
(The TQCC of Nature Reviews Immunology is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
IgA selects for fit, peace-loving fungi938
The mole rat’s secret to cancer resistance759
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies641
The danger theory of immunity revisited625
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis586
Heart failure affects innate immune memory508
Comparing neurological complications after COVID-19 vaccination and SARS-CoV-2 infection501
Regulation goes awry in the liver470
Lymphocytes in lockdown459
Early life antibiotics have lasting effects on the lung epithelium449
Vaccines only partially protect against Long COVID442
Viral infection and antiviral immunity in the oral cavity431
Decoding the human prenatal immune system with single-cell multi-omics370
The immunology of asthma and chronic rhinosinusitis357
Human immune organoids: a tool to study vaccine responses357
Challenges in developing personalized neoantigen cancer vaccines323
Muscle spindle macrophages regulate motor coordination316
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues315
Regulation of cGAS–STING signalling and its diversity of cellular outcomes309
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses296
Stressed tumours release immunosuppressive vesicles289
Omicron alone provides limited cross-protection288
Gut commensals promote antiviral immunity via extracellular vesicles270
Targeting malaria transmission265
Encouraging vaccine uptake: lessons from behavioural science261
Lessons from vaccine-induced immune thrombotic thrombocytopenia257
Human T follicular regulatory cells with helper and regulatory lineage origins252
The distinctive immune features of long COVID237
Neutrophils are dispensable for Shigella control: macrophages take centre stage233
B cells in central nervous system disease: diversity, locations and pathophysiology231
Novel insights into the immune response to bacterial T cell superantigens228
The NLR gene family: from discovery to present day223
A guide to adaptive immune memory221
Antiviral neutralizing antibodies: from in vitro to in vivo activity213
How bile acids and the microbiota interact to shape host immunity211
Mechanistic insights from inflammasome structures210
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer208
Salt sensitivity includes effects on immune cell signalling and metabolism208
The cancer-immune dialogue in the context of stress207
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells206
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells205
APOL1 variants contribute to racial disparity in sepsis201
Splenic stromal niches in homeostasis and immunity196
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease185
T cell–eosinophil collaboration179
You are what you ate: myeloid cells trained by fatty acids178
Bile duct tuft cells regulate immune defences176
Online immunology education for a global world167
Cross reactive T cells hold up against Omicron161
Author Correction: SARS-CoV-2 and HIV-1 – A Tale of Two Vaccines161
Author Correction: Perivascular macrophages in health and disease157
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC150
The OrganiX microfluidic system to recreate the complex tumour microenvironment149
The germinal centre B cell response to SARS-CoV-2147
Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses142
Feeding IgA+ plasma cells139
Mechanistic insights into Long COVID in hamsters139
Bacteria in tumours promote cancer progression137
JAKs drive innate-like TH9 cell activation in allergy137
Negative regulation of fungal immunity by STING134
Spatial resolution of host–microbiome interactions133
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint131
Low risk of CAR T cells going rogue127
Neutrophils make matrix to fortify barrier immunity125
The immunopathogenesis of narcolepsy type 1120
Author Correction: Cancer cell metabolism and antitumour immunity118
Monocytes rule energy metabolism with an iron fist114
Monkeypox: disease epidemiology, host immunity and clinical interventions113
Lessons in self-defence: inhibition of virus entry by intrinsic immunity113
Olfactory immunology: the missing piece in airway and CNS defence113
The biology of TREM receptors111
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies108
The interplay of immunology and cachexia in infection and cancer108
A guide to antigen processing and presentation108
Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?107
T cells target viral protein to remove senescent fibroblasts106
Foetal sex affects maternal and placental immune responses to SARS-CoV-2106
Rejuvenation through checkpoint inhibitors?97
Commensal fungi support granulocyte development96
Immune cells freeze in response to stress signalling96
Guardians of immune privilege96
mRNA vaccine for treating pancreatic cancer96
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy95
Podoplanin mediates stromal–immune crosstalk in the lymph node92
We need to keep an eye on avian influenza89
Local immune recognition of trophoblast in early human pregnancy: controversies and questions88
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells87
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases87
Immune-mediated inflammatory disease therapeutics: past, present and future86
DNA damage and repair in age-related inflammation85
Glomerulonephritis: immunopathogenesis and immunotherapy84
Early antiviral type I interferon impairs lung metastasis84
Bacterial serotonin induces Treg cells in neonates82
Turning on anti-tumour T cells via MTAP82
Pollution impairs lung defences with age81
Immune epigenome77
Hypoxia and IL-24 drive a sterile wound healing pathway76
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis71
CODEX multiplexed tissue imaging71
γδ T cells sense disturbance69
Boosting cytotoxic T cells for immunotherapy68
Asymptomatic SARS-CoV-2 linked to HLA-B*15:0168
Microbiota licenses protective CD8+ T cell responses against neonatal influenza67
Actin branching maintains tissue-resident mast cells65
A billion-year-old mechanism of innate immunity uncovered64
Integrated organ immunity: a path to a universal vaccine62
Lung-resident memory B cells class-switch to IgE61
Insights into immune cell–fibroblast communication in heart disease61
The renaissance of oral tolerance: merging tradition and new insights61
Defining myeloid-derived suppressor cells60
Using cross-species vaccination approaches to counter emerging infectious diseases59
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection58
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases58
IL-17 and IL-17-producing cells in protection versus pathology57
First glimpses into the mechanisms of Long COVID56
B cell-derived acetylcholine curbs haematopoiesis55
Effect of prenatal stress on the developing brain55
Immunology of food aversion54
The autoinflammatory disease APLAID is driven by G-CSF51
Defining the TH17 cell lineage50
The epigenetic ghost of infections past50
Author Correction: The immunology of long COVID49
A pan-cancer signature for dysfunctional T cells48
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis48
When ‘mild’ COVID-19 is not so mild47
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain47
Inflammatory rewiring46
Bacteria tag tumours for CAR T cell attack45
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis45
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies44
PerturbView: scalable image-based perturbation screens in cells and tissues44
Disturbance of cytoskeleton primes RIG-I-like receptors37
Modified uridines are the key to a successful message37
Understanding COVID-19-associated coagulopathy36
Modelling vaccination strategies for COVID-1935
Role of thymic stromal lymphopoietin in allergy and beyond35
The role of transcription factors in shaping regulatory T cell identity34
TCF1 in T cell immunity: a broadened frontier33
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy33
The role of T cells in age-related diseases32
The role of galectins in immunity and infection32
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity31
Linking Epstein-Barr virus infection to multiple sclerosis30
Transposon-derived decoy fine-tunes IFN responses30
Author Correction: The role of platelets in immune-mediated inflammatory diseases29
The diversity of CD8+ T cell dysfunction in cancer and viral infection29
CARD8 kills CD4+ T cells in response to HIV entry29
Targeting ER stress sensor restores immunogenicity of chemotherapy29
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors29
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid29
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?29
CRISPR screens for functional interrogation of immunity27
Human ILC2s can act as cytolytic killers27
Unconventional T cells shape tissue-specific lymph node responses27
Comparing paediatric COVID-19 with MIS-C26
Obesity-associated autoreactivity26
Focusing on the correct gene signatures for SLE26
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