Nature Reviews Immunology

Papers
(The TQCC of Nature Reviews Immunology is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
The mole rat’s secret to cancer resistance876
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies761
Heart failure affects innate immune memory616
Comparing neurological complications after COVID-19 vaccination and SARS-CoV-2 infection608
Regulation goes awry in the liver554
Lymphocytes in lockdown527
Early life antibiotics have lasting effects on the lung epithelium482
Vaccines only partially protect against Long COVID417
Muscle spindle macrophages regulate motor coordination372
Human immune organoids: a tool to study vaccine responses365
Decoding the human prenatal immune system with single-cell multi-omics361
BCG plus β-glucan trains neutrophils to beat bladder cancer321
The immunology of asthma and chronic rhinosinusitis313
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis294
The danger theory of immunity revisited293
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses292
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues280
Viral infection and antiviral immunity in the oral cavity269
Regulation of cGAS–STING signalling and its diversity of cellular outcomes265
Challenges in developing personalized neoantigen cancer vaccines261
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses257
Stressed tumours release immunosuppressive vesicles252
Omicron alone provides limited cross-protection247
Gut commensals promote antiviral immunity via extracellular vesicles244
Targeting malaria transmission241
Lessons from vaccine-induced immune thrombotic thrombocytopenia238
Encouraging vaccine uptake: lessons from behavioural science238
The NLR gene family: from discovery to present day230
Antiviral neutralizing antibodies: from in vitro to in vivo activity218
How bile acids and the microbiota interact to shape host immunity217
The distinctive immune features of long COVID201
Neutrophils are dispensable for Shigella control: macrophages take centre stage200
Novel insights into the immune response to bacterial T cell superantigens199
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells194
B cells in central nervous system disease: diversity, locations and pathophysiology188
Mechanistic insights from inflammasome structures181
A guide to adaptive immune memory177
Human T follicular regulatory cells with helper and regulatory lineage origins177
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer176
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells169
Salt sensitivity includes effects on immune cell signalling and metabolism158
T cell–eosinophil collaboration153
You are what you ate: myeloid cells trained by fatty acids152
Bile duct tuft cells regulate immune defences151
Online immunology education for a global world148
Cross reactive T cells hold up against Omicron146
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC143
Author Correction: Perivascular macrophages in health and disease143
Author Correction: SARS-CoV-2 and HIV-1 – A Tale of Two Vaccines143
Gut ILC2s remember IL-25142
APOL1 variants contribute to racial disparity in sepsis141
The cancer-immune dialogue in the context of stress139
Splenic stromal niches in homeostasis and immunity138
The OrganiX microfluidic system to recreate the complex tumour microenvironment132
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells130
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease129
The germinal centre B cell response to SARS-CoV-2128
Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses127
Mechanistic insights into Long COVID in hamsters125
Feeding IgA+ plasma cells122
Bacteria in tumours promote cancer progression121
JAKs drive innate-like TH9 cell activation in allergy121
Negative regulation of fungal immunity by STING120
Spatial resolution of host–microbiome interactions119
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint118
Low risk of CAR T cells going rogue117
Olfactory immunology: the missing piece in airway and CNS defence114
Monocytes rule energy metabolism with an iron fist111
Neutrophils make matrix to fortify barrier immunity109
Author Correction: Cancer cell metabolism and antitumour immunity103
The immunopathogenesis of narcolepsy type 1102
Lessons in self-defence: inhibition of virus entry by intrinsic immunity101
The spatial and temporal activation of macrophages during fibrosis100
The biology of TREM receptors96
Monkeypox: disease epidemiology, host immunity and clinical interventions94
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies93
A guide to antigen processing and presentation92
Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?90
The interplay of immunology and cachexia in infection and cancer90
Foetal sex affects maternal and placental immune responses to SARS-CoV-289
Guardians of immune privilege88
T cells target viral protein to remove senescent fibroblasts88
Commensal fungi support granulocyte development88
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy88
Rejuvenation through checkpoint inhibitors?88
DNA damage and repair in age-related inflammation86
Podoplanin mediates stromal–immune crosstalk in the lymph node86
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells85
We need to keep an eye on avian influenza82
mRNA vaccine for treating pancreatic cancer82
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases76
Immune-mediated inflammatory disease therapeutics: past, present and future75
Spatial immunometabolic zonation in tuberculosis granulomas75
Local immune recognition of trophoblast in early human pregnancy: controversies and questions74
Glomerulonephritis: immunopathogenesis and immunotherapy71
Bacterial serotonin induces Treg cells in neonates70
Pollution impairs lung defences with age70
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis68
Hypoxia and IL-24 drive a sterile wound healing pathway68
γδ T cells sense disturbance66
Boosting cytotoxic T cells for immunotherapy65
Asymptomatic SARS-CoV-2 linked to HLA-B*15:0165
Microbiota licenses protective CD8+ T cell responses against neonatal influenza64
Actin branching maintains tissue-resident mast cells63
A billion-year-old mechanism of innate immunity uncovered62
Early antiviral type I interferon impairs lung metastasis60
Insights into immune cell–fibroblast communication in heart disease58
Lung-resident memory B cells class-switch to IgE58
Integrated organ immunity: a path to a universal vaccine57
The renaissance of oral tolerance: merging tradition and new insights57
Turning on anti-tumour T cells via MTAP56
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases55
Defining myeloid-derived suppressor cells55
CODEX multiplexed tissue imaging53
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection51
IL-17 and IL-17-producing cells in protection versus pathology50
B cell-derived acetylcholine curbs haematopoiesis48
First glimpses into the mechanisms of Long COVID48
Effect of prenatal stress on the developing brain45
The autoinflammatory disease APLAID is driven by G-CSF44
When ‘mild’ COVID-19 is not so mild42
Author Correction: The immunology of long COVID42
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis42
The epigenetic ghost of infections past42
PerturbView: scalable image-based perturbation screens in cells and tissues42
A pan-cancer signature for dysfunctional T cells42
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis38
Bacteria tag tumours for CAR T cell attack37
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain37
Defining the TH17 cell lineage37
Disturbance of cytoskeleton primes RIG-I-like receptors37
Modified uridines are the key to a successful message36
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy36
Modelling vaccination strategies for COVID-1936
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies36
Immunology of food aversion35
The role of galectins in immunity and infection35
Understanding COVID-19-associated coagulopathy35
Role of thymic stromal lymphopoietin in allergy and beyond33
The role of transcription factors in shaping regulatory T cell identity33
CARD8 kills CD4+ T cells in response to HIV entry33
Transposon-derived decoy fine-tunes IFN responses33
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors30
Linking Epstein-Barr virus infection to multiple sclerosis30
Targeting ER stress sensor restores immunogenicity of chemotherapy30
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid30
CRISPR screens for functional interrogation of immunity29
Author Correction: The role of platelets in immune-mediated inflammatory diseases29
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?27
The diversity of CD8+ T cell dysfunction in cancer and viral infection27
Unconventional T cells shape tissue-specific lymph node responses26
Human ILC2s can act as cytolytic killers26
Obesity-associated autoreactivity25
Comparing paediatric COVID-19 with MIS-C23
Meningeal MAIT cells preserve brain homeostasis23
Regulation of innate-like activities of neonatal CD8+ T cells23
Focusing on the correct gene signatures for SLE23
Macrophage quality control of HSCs23
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