Nature Reviews Immunology

(The TQCC of Nature Reviews Immunology is 123. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
The NLRP3 inflammasome: molecular activation and regulation to therapeutics1723
Dendritic cells in cancer immunology and immunotherapy912
Macrophages as regulators of tumour immunity and immunotherapy882
DAMP-sensing receptors in sterile inflammation and inflammatory diseases617
Defining ‘T cell exhaustion’578
The gasdermins, a protein family executing cell death and inflammation564
Tumour-intrinsic resistance to immune checkpoint blockade533
The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease479
The intestinal microbiota fuelling metabolic inflammation417
Dendritic cell subsets in T cell programming: location dictates function394
TIM3 comes of age as an inhibitory receptor352
The human antibody response to influenza A virus infection and vaccination318
Heterogeneity of neutrophils308
Efferocytosis in health and disease272
Osteoimmunology: evolving concepts in bone–immune interactions in health and disease260
Metabolic coordination of T cell quiescence and activation254
The immunological anatomy of the skin252
Treg cell-based therapies: challenges and perspectives252
Itaconate: the poster child of metabolic reprogramming in macrophage function238
Sleep and inflammation: partners in sickness and in health229
B cell memory: building two walls of protection against pathogens215
Immunometabolism at the interface between macrophages and pathogens214
Small RNA-based antimicrobial immunity210
Calcium signalling in T cells209
Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?208
Immunometabolism and natural killer cell responses187
Pain and immunity: implications for host defence186
Immune mechanisms of hypertension186
New insights into the immune functions of complement185
Autophagy in the renewal, differentiation and homeostasis of immune cells183
How macrophages deal with death174
Mechanisms underlying T cell ageing171
Epigenetic regulation of the innate immune response to infection171
Precursor exhausted T cells: key to successful immunotherapy?168
Mining the microbiota for microbial and metabolite-based immunotherapies162
Targeting innate immune mediators in type 1 and type 2 diabetes156
Metabolic interventions in the immune response to cancer150
Mucosal-associated invariant T cells and disease148
Organoids in immunological research147
Interferon-λ orchestrates innate and adaptive mucosal immune responses140
Adaptive immune responses to primary and secondary dengue virus infections129
Functional interactions between innate lymphoid cells and adaptive immunity128
CAR T cell therapy: inroads to response and resistance126
Alternative mRNA splicing in cancer immunotherapy125
Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation123