Nature Reviews Immunology

(The TQCC of Nature Reviews Immunology is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
A guide to cancer immunotherapy: from T cell basic science to clinical practice2201
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages1805
Viral targets for vaccines against COVID-19803
Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity802
COVID-19: the vasculature unleashed776
Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape773
Immunological considerations for COVID-19 vaccine strategies766
The cGAS–STING pathway as a therapeutic target in inflammatory diseases762
A guide to vaccinology: from basic principles to new developments724
T cell responses in patients with COVID-19671
Considering how biological sex impacts immune responses and COVID-19 outcomes647
Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19596
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities575
Neutralizing monoclonal antibodies for treatment of COVID-19550
COVID-19 vaccines: modes of immune activation and future challenges521
Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?447
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans426
Tissue damage from neutrophil-induced oxidative stress in COVID-19420
Inflammation and immune dysfunction in Parkinson disease402
COVID-19 herd immunity: where are we?396
CD8+ T cell differentiation and dysfunction in cancer372
BCG-induced trained immunity: can it offer protection against COVID-19?364
Dysregulation of type I interferon responses in COVID-19353
The role of IgG Fc receptors in antibody-dependent enhancement338
Lactate modulation of immune responses in inflammatory versus tumour microenvironments337
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy335
Pre-existing immunity to SARS-CoV-2: the knowns and unknowns322
The first 12 months of COVID-19: a timeline of immunological insights320
The type I interferon response in COVID-19: implications for treatment306
Mucosal vaccines — fortifying the frontiers295
The inflammatory pathogenesis of colorectal cancer285
Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children264
Metabolic barriers to cancer immunotherapy251
The roles of extracellular vesicles in the immune system251
Neutrophils in cancer: heterogeneous and multifaceted248
γδ T cells in tissue physiology and surveillance242
Fibroblasts as immune regulators in infection, inflammation and cancer238
Interferon-γ: teammate or opponent in the tumour microenvironment?233
Not just antibodies: B cells and T cells mediate immunity to COVID-19233
Redox regulation of immunometabolism228
COVID-19: a case for inhibiting IL-17?227
Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection219
A guide to antigen processing and presentation218
Regulation of immune responses by the airway epithelial cell landscape217
Cross-reactive memory T cells and herd immunity to SARS-CoV-2217
Mitochondrial control of inflammation216
Inflammasome activation at the crux of severe COVID-19216
Natural killer cells in antiviral immunity210
Immunobiology and pathogenesis of hepatitis B virus infection207
Monkeypox: disease epidemiology, host immunity and clinical interventions205
SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact205
CD8+ T cell metabolism in infection and cancer201
Dissecting antibody-mediated protection against SARS-CoV-2200
IL-17 and IL-17-producing cells in protection versus pathology200
Targeting CD39 in cancer188
Immune cell-mediated features of non-alcoholic steatohepatitis187
Regulation of inflammation by the antioxidant haem oxygenase 1180
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity175
Neuromodulation by the immune system: a focus on cytokines170
The type I interferonopathies: 10 years on169
Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge168
GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches168
Transcriptional regulation of memory B cell differentiation166
The state of complement in COVID-19163
Genetic models of human and mouse dendritic cell development and function158
Constitutive immune mechanisms: mediators of host defence and immune regulation155
Autoantibodies in neurological disease151
The germinal centre B cell response to SARS-CoV-2151
Will SARS-CoV-2 variants of concern affect the promise of vaccines?149
A few good peptides: MHC class I-based cancer immunosurveillance and immunoevasion147
Early life microbial exposures and allergy risks: opportunities for prevention146
How transcription factors drive choice of the T cell fate144
Understanding COVID-19-associated coagulopathy142
Immunomodulation by endothelial cells — partnering up with the immune system?140
Estimating disease severity of Omicron and Delta SARS-CoV-2 infections140
Death by TNF: a road to inflammation139
Immune ageing at single-cell resolution134
Regulation of the nucleic acid-sensing Toll-like receptors133
Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders132
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses129
Milder disease with Omicron: is it the virus or the pre-existing immunity?124
Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey124
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy124
Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19123
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms118
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?116
Engineering IL-2 for immunotherapy of autoimmunity and cancer115
Tissue regulatory T cells: regulatory chameleons113
The impact of the gut microbiome on extra-intestinal autoimmune diseases109
Are COVID-19 vaccines safe in pregnancy?109
Immune-mediated inflammatory disease therapeutics: past, present and future109
NOD-like receptor-mediated plant immunity: from structure to cell death108
Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models107
Author Correction: Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages106
Glucocorticoids in T cell development, differentiation and function105
Bacterial origins of human cell-autonomous innate immune mechanisms105
The immunology of multiple sclerosis102
TCF1 in T cell immunity: a broadened frontier102
Is IL-6 a key cytokine target for therapy in COVID-19?102
Neuronal regulation of immunity: why, how and where?100
After 62 years of regulating immunity, dexamethasone meets COVID-1999
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy99
T cell regeneration after immunological injury98
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?97
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies95
The role of T cells in age-related diseases91
Cellular networks controlling T cell persistence in adoptive cell therapy90
The non-specific and sex-differential effects of vaccines89
A guide to interrogating immunometabolism88
Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination87
Passive antibody therapy in COVID-1987
Tissue-specific macrophages: how they develop and choreograph tissue biology86
Phase separation in immune signalling85
Allergen immunotherapy: past, present and future85
Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases84
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues83
Immunomodulation by radiotherapy in tumour control and normal tissue toxicity83
The immunology of long COVID81
Omicron, the great escape artist80
Diversity and dynamism of IgA−microbiota interactions80
Host-directed immunotherapy of viral and bacterial infections: past, present and future80
The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?79
The spatio-temporal control of effector T cell migration77
Heterogeneity in the initiation, development and function of type 2 immunity76
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases76
Tuning immunity through tissue mechanotransduction75
Myeloid cell-targeted therapies for solid tumours74
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection68
The interplay of immunology and cachexia in infection and cancer68
Clonal expansion of innate and adaptive lymphocytes68
COVID-19 vaccines: neutralizing antibodies and the alum advantage67
Crosstalk between the renin–angiotensin, complement and kallikrein–kinin systems in inflammation64
DNA damage and repair in age-related inflammation64
Lessons in self-defence: inhibition of virus entry by intrinsic immunity63
Targeting IL-6 trans-signalling: past, present and future prospects63
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses62
IL-9-producing T cells: potential players in allergy and cancer60
Functional categories of immune inhibitory receptors60
Immune responses to human fungal pathogens and therapeutic prospects59
B cells in central nervous system disease: diversity, locations and pathophysiology59
Immune and non-immune functions of adipose tissue leukocytes58
Innate immune detection of lipid oxidation as a threat assessment strategy58
COVID-19 and cellular senescence57
The biology of TREM receptors57
RHO GTPases: from new partners to complex immune syndromes57
Endemic SARS-CoV-2 will maintain post-pandemic immunity57
The role of chromatin loop extrusion in antibody diversification56
Will helminth co-infection modulate COVID-19 severity in endemic regions?56
Heterogeneity of type 2 innate lymphoid cells55
The link between circulating follicular helper T cells and autoimmunity55
Can we predict T cell specificity with digital biology and machine learning?55
Expanding dendritic cell nomenclature in the single-cell era55
Do cross-reactive antibodies cause neuropathology in COVID-19?54
Role of thymic stromal lymphopoietin in allergy and beyond54
Cerebral dysfunctions caused by sepsis during ageing54
Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?54
T cell-oriented strategies for controlling the COVID-19 pandemic53
Understanding COVID-19 in Africa52
Immunometabolism and HIV-1 pathogenesis: food for thought52
Omicron entry route51
Organellar homeostasis and innate immune sensing51
Gasdermins: making pores for pyroptosis50
Keeping track of the SARS-CoV-2 vaccine pipeline50
Building a T cell compartment: how immune cell development shapes function50
Signals of hope: gauging the impact of a rapid national vaccination campaign48
Blood clots and TAM receptor signalling in COVID-19 pathogenesis47
Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity?45
Immune evasion via SARS-CoV-2 ORF8 protein?45
The role of galectins in immunity and infection45
Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines45
A call to arms: helping family, friends and communities navigate the COVID-19 infodemic44
The multifunctional protein HMGB1: 50 years of discovery44
SARS-CoV-2 hybrid immunity: silver bullet or silver lining?43
New perspectives on the origins and heterogeneity of mast cells43
Modelling vaccination strategies for COVID-1942
Optimizing safety surveillance for COVID-19 vaccines41
Engaging innate immunity in HIV-1 cure strategies41
Tumour immunotherapy: lessons from predator–prey theory41