Nature Reviews Immunology

Article	Citations
Regulation goes awry in the liver	1047
Heart failure affects innate immune memory	991
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis	848
Early life antibiotics have lasting effects on the lung epithelium	848
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses	762
Vaccines only partially protect against Long COVID	527
Decoding the human prenatal immune system with single-cell multi-omics	495
Muscle spindle macrophages regulate motor coordination	430
BCG plus β-glucan trains neutrophils to beat bladder cancer	416
Albumin protects against deadly fungal infection	399
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	367
Metabolite and nutrient regulation of macrophages in obesity and metabolic disease	366
Human immune organoids: a tool to study vaccine responses	353
Shaping neutrophil morphology and function: the importance of a segmented nucleus	334
The danger theory of immunity revisited	332
Regulation of cGAS–STING signalling and its diversity of cellular outcomes	328
The immunology of asthma and chronic rhinosinusitis	321
Viral infection and antiviral immunity in the oral cavity	320
Challenges in developing personalized neoantigen cancer vaccines	318
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses	312
Omicron alone provides limited cross-protection	309
Gut commensals promote antiviral immunity via extracellular vesicles	307
Targeting malaria transmission	294
Novel insights into the immune response to bacterial T cell superantigens	287
The distinctive immune features of long COVID	287

Human T follicular regulatory cells with helper and regulatory lineage origins	268
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells	257
Neutrophils are dispensable for Shigella control: macrophages take centre stage	242
Stressed tumours release immunosuppressive vesicles	238
Encouraging vaccine uptake: lessons from behavioural science	231
A guide to adaptive immune memory	228
Mechanistic insights from inflammasome structures	228
Antiviral neutralizing antibodies: from in vitro to in vivo activity	223
The NLR gene family: from discovery to present day	222
How bile acids and the microbiota interact to shape host immunity	210
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells	205
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer	192
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells	189
You are what you ate: myeloid cells trained by fatty acids	189
T cell–eosinophil collaboration	182
Gut ILC2s remember IL-25	176
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC	170
Online immunology education for a global world	168
Salt sensitivity includes effects on immune cell signalling and metabolism	163
The OrganiX microfluidic system to recreate the complex tumour microenvironment	160
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease	160
Splenic stromal niches in homeostasis and immunity	159
The cancer-immune dialogue in the context of stress	159
Feeding IgA+ plasma cells	154
JAKs drive innate-like TH9 cell activation in allergy	154
Negative regulation of fungal immunity by STING	153
Mechanistic insights into Long COVID in hamsters	149
Spatial resolution of host–microbiome interactions	147
Low risk of CAR T cells going rogue	140
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint	135
Monocytes rule energy metabolism with an iron fist	131
Author Correction: Cancer cell metabolism and antitumour immunity	118
Bacteria in tumours promote cancer progression	118
The immunopathogenesis of narcolepsy type 1	117
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy	113
Neutrophils make matrix to fortify barrier immunity	113
The spatial and temporal activation of macrophages during fibrosis	113
Monkeypox: disease epidemiology, host immunity and clinical interventions	112
Olfactory immunology: the missing piece in airway and CNS defence	111
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	110
The biology of TREM receptors	107
Commensal fungi support granulocyte development	106
Rejuvenation through checkpoint inhibitors?	106
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy	105
T cells target viral protein to remove senescent fibroblasts	105
mRNA vaccine for treating pancreatic cancer	96
We need to keep an eye on avian influenza	94
Cytokine multimerization: when more is more and sometimes less	93
Kupffer cells in liver homeostasis and disease: from immune sentinels to metabolic gatekeepers	89
Early life allergen sensitivity starts in the skin	88

Spatial immunometabolic zonation in tuberculosis granulomas	83
Podoplanin mediates stromal–immune crosstalk in the lymph node	80
Guardians of immune privilege	76
Germinal centre IL-4 enforces tissue confinement of IgE memory	75
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells	73
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases	70
Local immune recognition of trophoblast in early human pregnancy: controversies and questions	69
Glomerulonephritis: immunopathogenesis and immunotherapy	68
DNA damage and repair in age-related inflammation	68
The promise of immunotherapy for central nervous system tumours	66
Bacterial serotonin induces Treg cells in neonates	65
Pollution impairs lung defences with age	65
Boosting cytotoxic T cells for immunotherapy	61
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis	61
Early antiviral type I interferon impairs lung metastasis	60
Actin branching maintains tissue-resident mast cells	56
Lung-resident memory B cells class-switch to IgE	56
Microbiota licenses protective CD8+ T cell responses against neonatal influenza	55
Asymptomatic SARS-CoV-2 linked to HLA-B*15:01	55
Hypoxia and IL-24 drive a sterile wound healing pathway	52
Turning on anti-tumour T cells via MTAP	51
Insights into immune cell–fibroblast communication in heart disease	51
CODEX multiplexed tissue imaging	50
Defining myeloid-derived suppressor cells	49
IL-17 and IL-17-producing cells in protection versus pathology	48
The renaissance of oral tolerance: merging tradition and new insights	48
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection	48
Integrated organ immunity: a path to a universal vaccine	48
The autoinflammatory disease APLAID is driven by G-CSF	47
When ‘mild’ COVID-19 is not so mild	47
Effect of prenatal stress on the developing brain	47
Bacteria tag tumours for CAR T cell attack	46
PerturbView: scalable image-based perturbation screens in cells and tissues	46
Disturbance of cytoskeleton primes RIG-I-like receptors	45
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain	45
Author Correction: The immunology of long COVID	45
NK cell mechanosensing through CD16a	44
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies	44
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis	42
Immunology of food aversion	42
Harnessing mucosal immunity for protective vaccines	41
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis	41
The ageing immune system as a driver of systemic ageing	37
The role of transcription factors in shaping regulatory T cell identity	37
Role of thymic stromal lymphopoietin in allergy and beyond	36
Understanding COVID-19-associated coagulopathy	35
The role of galectins in immunity and infection	35
Inhibition of NR4A1 potentiates a CD8+ T cell response against active tuberculosis	33
Targeting ER stress sensor restores immunogenicity of chemotherapy	33
CARD8 kills CD4+ T cells in response to HIV entry	33
Transposon-derived decoy fine-tunes IFN responses	33
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors	32
Author Correction: The role of platelets in immune-mediated inflammatory diseases	32
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid	31
Contextualizing TH17 cells in cancer	30
Metabolites as signalling molecules in the tumour immune microenvironment	30
CRISPR screens for functional interrogation of immunity	28
The diversity of CD8+ T cell dysfunction in cancer and viral infection	28
Macrophage quality control of HSCs	27
Regulation of innate-like activities of neonatal CD8+ T cells	27
Unconventional T cells shape tissue-specific lymph node responses	26
Focusing on the correct gene signatures for SLE	26
Human ILC2s can act as cytolytic killers	26
Obesity-associated autoreactivity	26
Signal length not strength guides T cell fate	25
Osteoblast-derived ATP maintains bone marrow plasma cells	25
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease	25
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment	25
Type I interferon at the crossroads of metastatic dissemination	25
Cardiometabolic syndrome — an emergent feature of Long COVID?	23
Ageing tissue fibroblasts support lung inflammaging	22
Meningeal MAIT cells preserve brain homeostasis	21
STAT5A antagonizes TOX in CD8+ T cell exhaustion	21
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses	20
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy	19
A skull bone marrow niche for antitumour neutrophils in glioblastoma	19
Local Treg cell loss reprogrammes systemic antitumour immunity without breaking tolerance	19
Clock genes keep intestinal ILC3s ticking	18
Squeeze to arm	18
BRD4 acts as a pH sensor to tune inflammation	18

RORγt+ antigen-presenting cells mediate food tolerance	18
Rethinking pDCs: a questionable ally in immunity?	18
ILC2–neuron cross-talk regulates pain sensitivity and gait	17
Insulin neoantigen elicits memory T cell activation in diabetes	17
T cell competition in multi-neoantigen cancer vaccines	16
Sleep deprivation whips up cytokine storm	16
Membrane organization by tetraspanins and galectins shapes lymphocyte function	16
Guidelines for T cell nomenclature	15
Fibroblasts as regulators of lung immunity, repair and fibrosis	15
Intracellular bacteria in cancer cells promote immunosuppression in the metastatic niche	15
Live vaccine development through targeted protein degradation	15
Allergen immunotherapy: past, present and future	14
Fever affects T cell fate	14
Opportunities and challenges for T cell-based influenza vaccines	14
Fired up in the bone marrow	14
Redefining our vision: an updated guide to the ocular immune system	14
Brief blockade of type I IFN increases CD8+ T cell memory	13
Tumour lactate bars B cell entry	13
Aspirin helps T cells to stop cancer spread	13
Hypoxia-induced epigenetic reprogramming of neutrophil progenitors	13
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis	13
Cytokines target distinct brain areas to modulate behavioural responses	12
Autoimmune T cells identified in ALS	12
Proteotoxic shock is a mechanistic driver of T cell exhaustion	12
Engineered γδ T cells show promise in bone tumours	12
Neutrophils release inflammation-resolving vesicles	11
Immune control of brain physiology	11
Bone marrow inflammation in haematological malignancies	11
Bacteria form unique biofilms to kill immune cells	11
Defining the balance between optimal immunity and immunopathology in influenza virus infection	11
Author Correction: The effect of physical exercise on anticancer immunity	11
Organoids identify a role for IL-7 in coeliac disease	10
Pain-sensing neurons calm the gut	10
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria	10
Clonal haematopoiesis and dysregulation of the immune system	10
Daughters forget, mothers remember	10
Trogocytosis of CARs depends on transmembrane domains	9
Universal LIPSTIC: a new tool for decoding cellular interactions	9
Clearing the hurdles for CAR-T cell treatment	9
Abortive infection: T cells as early, antibody-independent defenders	8
T cell exhaustion: early or late in tumour progression?	8
From TCR fundamental research to innovative chimeric antigen receptor design	8
A nuclear STING in the tail for canonical signalling	8
Immunological factors linked to geographical variation in vaccine responses	8
Negative regulation of AHR essential for intestinal homeostasis	8
Gut macrophages and Parkinson’s disease	8
Beyond exhaustion: the unique characteristics of CD8+ T cell dysfunction in chronic HBV infection	8
Low serotonin linked to long COVID	7
Assessing the generation of tissue resident memory T cells by vaccines	7
Orally delivered lactate-producing bacteria limit CNS autoimmunity	7
Therapeutic induction of antigen-specific immune tolerance	7
How neuroinflammation weakens muscles	7
A role for microglia in mediating the microbiota–gut–brain axis	7
How to respond when biomedical science and global health is under existential threat	6
T cell nomenclature: from subsets to modules	6
Time of day determines cancer immunotherapy response	6
Tuning immunity through tissue mechanotransduction	6
HDAC9 association with heart disease linked to NLRP3 inflammasome activation	6
Myeloid cell-targeted therapies for solid tumours	6
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD1	6
The immunology of vitiligo	6
Understanding NK cell heterogeneity	6
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia	6
The immunology of type 1 diabetes	6
Rejuvenating an old immune system	5
Tumour cells mimic erythroblasts to hijack iron from bone marrow macrophages	5
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective	5
Brief diet changes affect immunity	5
An inter-organ neuro–immuno–endocrine circuit for glucose homeostasis	5
IL-17A–HIF1α axis in epithelial wound repair	5
Connection and communication between the nervous and immune systems	5
Fasting affects monocyte lifespan and migration	5
How T cells handle lipids	5
Reindeer antlers model skin regeneration	5
Understanding vertebrate immunity through comparative immunology	5
Lymphatic expression of TBX1 helps to heal the heart	4
Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines	4
Role of the microbiota in response to and recovery from cancer therapy	4
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation	4
Neuron–eosinophil circuit explains stress-induced eczema flares	4
Cancer immune evasion, immunoediting and intratumour heterogeneity	4
Have a cake and eat it too: the importance of metaphors in research communication	4
Tracking the infant immune response to SARS-CoV-2	4
Trained immunity in chronic inflammatory diseases and cancer	4
Considering innate immune responses in SARS-CoV-2 infection and COVID-19	4
Can we improve immune health by restoring microbial biodiversity?	4
Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites	4
Cancer cell metabolism and antitumour immunity	4
Lung-migrating helminths can enhance immunity to SARS-CoV-2	4
T-regulating opioid withdrawal	4
Linking tumour angiogenesis and tumour immunity	4
Short-chain fatty acids: linking diet, the microbiome and immunity	4
Progress in the development of cytokine armoured CAR T cells	4
Iron and the immune system	4
Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation	4