Nature Reviews Immunology

Papers
(The H4-Index of Nature Reviews Immunology is 94. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)
ArticleCitations
The cGAS–STING pathway as a therapeutic target in inflammatory diseases986
Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity973
A guide to vaccinology: from basic principles to new developments850
Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape848
Viral targets for vaccines against COVID-19842
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities691
Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19657
Neutralizing monoclonal antibodies for treatment of COVID-19587
COVID-19 vaccines: modes of immune activation and future challenges558
Inflammation and immune dysfunction in Parkinson disease539
Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?513
CD8+ T cell differentiation and dysfunction in cancer483
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans445
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy429
The roles of extracellular vesicles in the immune system383
Mucosal vaccines — fortifying the frontiers354
The inflammatory pathogenesis of colorectal cancer346
The first 12 months of COVID-19: a timeline of immunological insights340
Mitochondrial control of inflammation327
Neutrophils in cancer: heterogeneous and multifaceted324
IL-17 and IL-17-producing cells in protection versus pathology318
Metabolic barriers to cancer immunotherapy304
A guide to antigen processing and presentation290
Fibroblasts as immune regulators in infection, inflammation and cancer289
γδ T cells in tissue physiology and surveillance288
Regulation of immune responses by the airway epithelial cell landscape281
Interferon-γ: teammate or opponent in the tumour microenvironment?279
Redox regulation of immunometabolism275
CD8+ T cell metabolism in infection and cancer265
Monkeypox: disease epidemiology, host immunity and clinical interventions257
Immune cell-mediated features of non-alcoholic steatohepatitis253
Death by TNF: a road to inflammation247
Immunobiology and pathogenesis of hepatitis B virus infection246
Natural killer cells in antiviral immunity242
Inflammasome activation at the crux of severe COVID-19237
SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact235
Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection227
Regulation of inflammation by the antioxidant haem oxygenase 1225
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity224
Cross-reactive memory T cells and herd immunity to SARS-CoV-2222
The type I interferonopathies: 10 years on208
Neuromodulation by the immune system: a focus on cytokines200
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy192
Transcriptional regulation of memory B cell differentiation186
The state of complement in COVID-19185
Immunomodulation by endothelial cells — partnering up with the immune system?185
Understanding COVID-19-associated coagulopathy178
Autoantibodies in neurological disease176
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses175
The germinal centre B cell response to SARS-CoV-2173
Tissue-specific macrophages: how they develop and choreograph tissue biology166
Regulation of the nucleic acid-sensing Toll-like receptors165
Estimating disease severity of Omicron and Delta SARS-CoV-2 infections162
Immune ageing at single-cell resolution161
Will SARS-CoV-2 variants of concern affect the promise of vaccines?153
Engineering IL-2 for immunotherapy of autoimmunity and cancer150
Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey149
The immunology of long COVID148
The impact of the gut microbiome on extra-intestinal autoimmune diseases147
Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders146
The immunology of multiple sclerosis143
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies142
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms140
Immune-mediated inflammatory disease therapeutics: past, present and future139
Bacterial origins of human cell-autonomous innate immune mechanisms136
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?132
Milder disease with Omicron: is it the virus or the pre-existing immunity?132
Tissue regulatory T cells: regulatory chameleons129
Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19129
Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases128
TCF1 in T cell immunity: a broadened frontier125
Glucocorticoids in T cell development, differentiation and function123
NOD-like receptor-mediated plant immunity: from structure to cell death123
Cellular networks controlling T cell persistence in adoptive cell therapy122
Targeting IL-6 trans-signalling: past, present and future prospects122
Allergen immunotherapy: past, present and future119
Are COVID-19 vaccines safe in pregnancy?117
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy115
Tuning immunity through tissue mechanotransduction114
T cell regeneration after immunological injury113
Immunomodulation by radiotherapy in tumour control and normal tissue toxicity113
Is IL-6 a key cytokine target for therapy in COVID-19?113
Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models111
DNA damage and repair in age-related inflammation105
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?105
Phase separation in immune signalling103
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues102
Host-directed immunotherapy of viral and bacterial infections: past, present and future102
Immune responses to human fungal pathogens and therapeutic prospects102
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases101
Myeloid cell-targeted therapies for solid tumours98
The role of T cells in age-related diseases98
A guide to interrogating immunometabolism98
Diversity and dynamism of IgA−microbiota interactions95
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