OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Molecular Diagnostics is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)

Article	Citations
LAMP Diagnostics at the Point-of-Care: Emerging Trends and Perspectives for the Developer Community	139
The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery	44
Advances in tests for colorectal cancer screening and diagnosis	43
The diagnostic methods in the COVID-19 pandemic, today and in the future	42
Rapid lateral flow tests for the detection of SARS-CoV-2 neutralizing antibodies	42
The diagnostic and prognostic role of neutrophil-to-lymphocyte ratio in COVID-19: a systematic review and meta-analysis	40
Noninvasive detection of COPD and Lung Cancer through breath analysis using MOS Sensor array based e-nose	36
Critical insight into recombinase polymerase amplification technology	35
Developing multiplex ddPCR assays for SARS-CoV-2 detection based on probe mix and amplitude based multiplexing	32
Role of N6-methyladenosine modification in pathogenesis of ischemic stroke	32
Diagnosis for COVID-19: current status and future prospects	31
Emerging circulating MiRNAs and LncRNAs in upper gastrointestinal cancers	25
Enzymatic cross-linking of collagens in organ fibrosis – resolution and assessment	25
Ultrasensitive circulating tumor DNA analysis enables precision medicine: experimental workflow considerations	24
Predictive biomarkers of response to immune checkpoint inhibitors in hepatocellular carcinoma	23
Saliva as a sample type for SARS-CoV-2 detection: implementation successes and opportunities around the globe	22
Aptamer-based sensing of breast cancer biomarkers: a comprehensive review of analytical figures of merit	22
Liquid biopsy from research to clinical practice: focus on non-small cell lung cancer	22
Liquid biopsy in head and neck squamous cell carcinoma: circulating tumor cells, circulating tumor DNA, and exosomes	22
Nanomaterial-based Optical and Electrochemical Biosensors for Amyloid beta and Tau: Potential for early diagnosis of Alzheimer’s Disease	22
A review on current diagnostic techniques for COVID-19	22
Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives	22
Blood-based traumatic brain injury biomarkers – Clinical utilities and regulatory pathways in the United States, Europe and Canada	22
Antimicrobial resistance prediction in Neisseria gonorrhoeae: current status and future prospects	22
Diagnosis of SARS-CoV-2 infection in the setting of the cytokine release syndrome	22

Circulating tumor cell clusters: Insights into tumour dissemination and metastasis	21
Advances in RT-LAMP for COVID-19 testing and diagnosis	21
An overview of using fungal DNA for the diagnosis of invasive mycoses	21
Predictive biomarkers for systemic therapy of hepatocellular carcinoma	20
Advances in gold nanoparticle technology as a tool for diagnostics and treatment of cancer	19
A review on human body fluids for the diagnosis of viral infections: scope for rapid detection of COVID-19	19
RAD51 as a functional biomarker for homologous recombination deficiency in cancer: a promising addition to the HRD toolbox?	19
Concentration of cell-free DNA in different tumor types	19
Performance comparison of the Cobas® Liat® and Cepheid® GeneXpert® systems on SARS-CoV-2 detection in nasopharyngeal swab and posterior oropharyngeal saliva	19
Human tear fluid analysis for clinical applications: progress and prospects	18
Diagnostic salivary biomarkers in oral cancer and oral potentially malignant disorders and their relationships to risk factors – A systematic review	18
dPCR application in liquid biopsies: divide and conquer	18
Emerging Role of Extracellular Vesicles in Biomarking the Gastrointestinal Diseases	17
Tumor treating fields: a comprehensive overview of the underlying molecular mechanism	17
Point-of-care diagnostics for invasive aspergillosis: nearing the finish line	17
Diagnostic and Prognostic Significance of Dysregulated Expression of Circular RNAs in Osteosarcoma	17
Circular RNAs: novel diagnostic and therapeutic targets for ischemic stroke	17
New and developing diagnostic platforms for COVID-19: A systematic review	16
Potential of CRISPR/Cas system in the diagnosis of COVID-19 infection	16
Clinical relevance ofliquid biopsyin breast cancer: update in 2020	16
A profile of the binx health io® molecular point-of-care test for chlamydia and gonorrhea in women and men	16
Mid-regional pro-adrenomedullin as a supplementary tool to clinical parameters in cases of suspicion of infection in the emergency department	16
Recent advances in the diagnosis monkeypox: implications for public health	16
Cervical cancer risk profiling: molecular biomarkers predicting the outcome of hrHPV infection	15
Future potential of metagenomics in microbiology laboratories	15
Improving laboratory diagnostics in myasthenia gravis	15
Quantifying SARS-CoV-2 viral load: current status and future prospects	15
Exploring the real-world effect of the SARS-CoV-2 pandemic on the molecular diagnostics for cancer patients and high-risk individuals	15
Metabolic profile of the Warburg effect as a tool for molecular prognosis and diagnosis of cancer	15
Circulating microRNA biomarkers in melanoma and non-melanoma skin cancer	15
Dysregulation of lncRNA-H19 in cardiometabolic diseases and the molecular mechanism involved : a systematic review	15
Molecular charcterization of lung adenocarcinoma combining whole exome sequencing, copy number analysis and gene expression profiling	15
Research tests for the diagnosis of tuberculosis infection	14
MicroRNA-217: a therapeutic and diagnostic tumor marker	14
Noninvasive prenatal screening for fetal sex chromosome aneuploidies	14
Clinical genomics and contextualizing genome variation in the diagnostic laboratory	14
Brain tumors and circulating micrornas: a systematic review and diagnostic meta-analysis	14
The importance of genomic analysis in cracking the coronavirus pandemic	14
Recent advances in the diagnosis of COVID-19: a bird’s eye view	14
Quantitative versus qualitative estrogen and luteinizing hormone testing for personal fertility monitoring	14
True or false: what are the factors that influence COVID-19 diagnosis by RT-qPCR?	13
Common markers of testicular Sertoli cells	13
Oral Potentially Malignant Disorders (OPMD): What is the clinical utility of dysplasia grade?	13
Applications of the CRISPR-Cas system for infectious disease diagnostics	13
Identification of the candidate lncRNA biomarkers for acute kidney injury: a systematic review and meta-analysis	13
Impact of non-antibiotic drugs on the human intestinal microbiome	13
The diagnostic accuracy of seven commercial molecular in vitro SARS-CoV-2 detection tests: a rapid meta-analysis	13
The clinical application of metagenomic next-generation sequencing for detecting pathogens in bronchoalveolar lavage fluid: case reports and literature review	13
Application of selected biosensor techniques in clinical diagnostics	13
Spatial profiling technologies and applications for brain cancers	12

Cell-free DNA as a potential biomarker for preeclampsia	12
Optimizing testing regimes for the detection of COVID-19 in children and older adults	12
Diagnostic accuracy of cerebrospinal fluid and serum-isolated extracellular vesicles for glioblastoma: a systematic review and meta-analysis	12
Viral metagenomic sequencing in the diagnosis of meningoencephalitis: a review of technical advances and diagnostic yield	12
Unveiling the underpinnings of various non-conventional ELISA variants: a review article	11
microRNAs as novel diagnostic biomarkers in endometriosis patients: a systematic review and meta-analysis	11
Rapid metagenomics for diagnosis of bloodstream and respiratory tract nosocomial infections: current status and future prospects	11
Point-of-care COVID-19 testing in the emergency department: current status and future prospects	11
ASSURED-SQVM diagnostics for COVID-19: addressing the why, when, where, who, what and how of testing	11
Current and future strategies for diagnostic and management of obstructive sleep apnea	10
Assessing our approach to diagnosing Fibromyalgia	10
Salivary biomarkers associated with obstructive sleep apnea: a systematic review	10
Radiomics and theranostics with molecular and metabolic probes in prostate cancer: toward a personalized approach	10
Advances in the clinical use of collagen as biomarker of liver fibrosis	10
Utility of droplet digital PCR and NGS-based CNV clinical assays in hearing loss diagnostics: current status and future prospects	10
Construction of a 5-methylcytosine-Related Molecular Signature to Inform the Prognosis and Immunotherapy of Lung Squamous Cell Carcinoma	10
Advancing cervical cancer diagnosis and screening with spectroscopy and machine learning	9
Recent advances in rapid antimicrobial susceptibility testing systems	9
Neuroimaging with PET/CT in chronic traumatic encephalopathy: what nuclear medicine can do to move the field forward	9
Updates in diagnosing polycystic ovary syndrome-related infertility	9
An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections	9
At-home coronavirus testing: the next game-changer?	9
The relationship between positivity for COVID-19 RT-PCR and symptoms, clinical findings, and mortality in Turkey	9
Investigation of LOY in Prostate, Pancreatic, and Colorectal Cancers in males: A case–control study	9
Long non-coding RNAs and their potential impact on diagnosis, prognosis, and therapy in prostate cancer: racial, ethnic, and geographical considerations	9
The prenatal exome – a door to prenatal diagnostics?	9
Beyond the Usual Suspects: Expanding on Mutations and Detection for Familial Hypercholesterolemia	9
The detrimental impact of elevated Ferritin to Iron ratio on in-hospital prognosis of patients with COVID-19	9
The potential diagnostic value of extracellular vesicle miRNA for human non-small cell lung cancer: a systematic review and meta-analysis	9
Diagnostic value of monocyte to high-density lipoprotein ratio in acute aortic dissection in a Chinese han population	9
Highly sensitive droplet digital PCR-based diagnostics for the surveillance of malaria vector populations in low transmission and incipient resistance settings	9
Nuclease activity: an exploitable biomarker in bacterial infections	9
Using lipocalin as a prognostic biomarker in acute kidney injury	9
Brain exosomes as minuscule information hub for Autism Spectrum Disorder	9