Lab on a Chip

Papers
(The TQCC of Lab on a Chip is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)
ArticleCitations
Point-of-care testing detection methods for COVID-19176
Vascularized organoids on a chip: strategies for engineering organoids with functional vasculature171
An outlook on microfluidics: the promise and the challenge163
Conventional and emerging strategies for the fabrication and functionalization of PDMS-based microfluidic devices137
High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows131
Single-cell microfluidic impedance cytometry: from raw signals to cell phenotypes using data analytics121
A microfluidic-integrated lateral flow recombinase polymerase amplification (MI-IF-RPA) assay for rapid COVID-19 detection115
Engineering neurovascular organoids with 3D printed microfluidic chips92
Accelerating innovation and commercialization through standardization of microfluidic-based medical devices86
Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures85
Recent innovations in cost-effective polymer and paper hybrid microfluidic devices78
Anin vitrovascularized micro-tumor model of human colorectal cancer recapitulatesin vivoresponses to standard-of-care therapy75
HiPSC-derived multi-organoids-on-chip system for safety assessment of antidepressant drugs74
Controllable fusion of human brain organoids using acoustofluidics67
Standardisation needs for organ on chip devices65
Simulating drug concentrations in PDMS microfluidic organ chips65
Understanding and improving FDM 3D printing to fabricate high-resolution and optically transparent microfluidic devices62
Microfluidic-based capture and release of cancer-derived exosomes via peptide–nanowire hybrid interface62
Microfluidics and surface-enhanced Raman spectroscopy, a win–win combination?62
Autonomous lab-on-paper for multiplexed, CRISPR-based diagnostics of SARS-CoV-261
Multiphysics microfluidics for cell manipulation and separation: a review59
Microfluidic technologies for nanoparticle formation59
Machine learning for microfluidic design and control58
A thread/fabric-based band as a flexible and wearable microfluidic device for sweat sensing and monitoring58
Neural network-enhanced real-time impedance flow cytometry for single-cell intrinsic characterization57
Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions56
A high-throughput multiplexed microfluidic device for COVID-19 serology assays55
A flux-adaptable pump-free microfluidics-based self-contained platform for multiplex cancer biomarker detection55
Nanoparticle protein corona: from structure and function to therapeutic targeting55
Engineering a sustainable future for point-of-care diagnostics and single-use microfluidic devices55
Printed microfluidic sweat sensing platform for cortisol and glucose detection54
3D printed microfluidics: advances in strategies, integration, and applications54
Materials and methods for droplet microfluidic device fabrication54
The acoustic droplet printing of functional tumor microenvironments52
Thin-film-transistor digital microfluidics for high value in vitro diagnostics at the point of need52
Speeding up reconstruction of 3D tomograms in holographic flow cytometry via deep learning51
Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant read-outs for tissue permeability and vascular structure51
Bubbles in microfluidics: an all-purpose tool for micromanipulation49
Tubular human brain organoids to model microglia-mediated neuroinflammation49
Membrane integration into PDMS-free microfluidic platforms for organ-on-chip and analytical chemistry applications49
“One-to-three” droplet generation in digital microfluidics for parallel chemiluminescence immunoassays49
Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out48
Extracellular vesicle mediated feto-maternal HMGB1 signaling induces preterm birth48
Inertial microfluidics: current status, challenges, and future opportunities47
Biomedical optical fibers46
Liquid marble-based digital microfluidics – fundamentals and applications46
Self-powered droplet manipulation system for microfluidics based on triboelectric nanogenerator harvesting rotary energy46
High throughput transepithelial electrical resistance (TEER) measurements on perfused membrane-free epithelia45
Label-free microfluidic cell sorting and detection for rapid blood analysis45
Fiber optic hydrogen sensor based on a Fabry–Perot interferometer with a fiber Bragg grating and a nanofilm45
Liver organ-on-chip models for toxicity studies and risk assessment44
Plasmonic nanobowtiefluidic device for sensitive detection of glioma extracellular vesicles by Raman spectrometry44
Microneedle-based transdermal detection and sensing devices44
Microliter ultrafast centrifuge platform for size-based particle and cell separation and extraction using novel omnidirectional spiral surface acoustic waves42
Advances in microfluidic extracellular vesicle analysis for cancer diagnostics42
Point-of-care diagnostics: recent developments in a pandemic age42
Microscopic artificial cilia – a review41
Interfacing cells with organic transistors: a review ofin vitroandin vivoapplications41
Tailored point-of-care biosensors for liquid biopsy in the field of oncology41
Intelligent acoustofluidics enabled mini-bioreactors for human brain organoids41
Simple and fast isolation of circulating exosomes with a chitosan modified shuttle flow microchip for breast cancer diagnosis40
Recent advances in the microfluidic production of functional microcapsules by multiple-emulsion templating40
Biologically inspired micro-robotic swimmers remotely controlled by ultrasound waves39
Nonlinear microfluidics: device physics, functions, and applications39
Lateral flow assays for hormone detection39
Unconventional acoustic approaches for localized and designed micromanipulation39
User-friendly image-activated microfluidic cell sorting technique using an optimized, fast deep learning algorithm38
Microdissected “cuboids” for microfluidic drug testing of intact tissues38
Tumor-on-a-chip platforms to study cancer–immune system crosstalk in the era of immunotherapy38
Direct isolation of circulating extracellular vesicles from blood for vascular risk profiling in type 2 diabetes mellitus37
Design of functional nanoparticles by microfluidic platforms as advanced drug delivery systems for cancer therapy37
A multilayered blood vessel/tumor tissue chip to investigate T cell infiltration into solid tumor tissues37
Interstitial flow enhances the formation, connectivity, and function of 3D brain microvascular networks generated within a microfluidic device37
Retinal organoids on-a-chip: a micro-millifluidic bioreactor for long-term organoid maintenance37
A portable, 3D printed, microfluidic device for multiplexed, real time, molecular detection of the porcine epidemic diarrhea virus, transmissible gastroenteritis virus, and porcine deltacoronavirus at37
Recent microfluidic advances in submicron to nanoparticle manipulation and separation36
A 3D human adipose tissue model within a microfluidic device36
Ultraviolet-induced in situ gold nanoparticles for point-of-care testing of infectious diseases in loop-mediated isothermal amplification36
Vasculature-on-a-chip platform with innate immunity enables identification of angiopoietin-1 derived peptide as a therapeutic for SARS-CoV-2 induced inflammation36
Simultaneous single-cell phenotype analysis of hepatocellular carcinoma CTCs using a SERS-aptamer based microfluidic chip36
Cascaded filter deterministic lateral displacement microchips for isolation and molecular analysis of circulating tumor cells and fusion cells36
Rapid and precise tumor cell separation using the combination of size-dependent inertial and size-independent magnetic methods35
Construction of a high fidelity epidermis-on-a-chip for scalable in vitro irritation evaluation35
Establishment of a human three-dimensional chip-based chondro-synovial coculture joint model for reciprocal cross talk studies in arthritis research35
Gear-shaped micromixer for synthesis of silica particles utilizing inertio-elastic flow instability35
Deciphering impedance cytometry signals with neural networks35
Submicron-precision particle characterization in microfluidic impedance cytometry with double differential electrodes34
Wearable chem-biosensing devices: from basic research to commercial market34
Automated biophysical classification of apoptotic pancreatic cancer cell subpopulations by using machine learning approaches with impedance cytometry34
Fabrication of tunable, high-molecular-weight polymeric nanoparticles via ultrafast acoustofluidic micromixing34
Sensing morphogenesis of bone cells under microfluidic shear stress by holographic microscopy and automatic aberration compensation with deep learning34
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips34
A microfluidic cathodic photoelectrochemical biosensor chip for the targeted detection of cytokeratin 19 fragments 21-134
A review on microrobots driven by optical and magnetic fields33
Recent advances in lab-on-paper diagnostic devices using blood samples33
Fabrication of monodisperse alginate microgel beads by microfluidic picoinjection: a chelate free approach33
Investigations on T cell transmigration in a human skin-on-chip (SoC) model33
Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers33
A novel human arterial wall-on-a-chip to study endothelial inflammation and vascular smooth muscle cell migration in early atherosclerosis33
Review of microfluidic approaches for fabricating intelligent fiber devices: importance of shape characteristics33
An electricity- and instrument-free infectious disease sensor based on a 3D origami paper-based analytical device33
Real-time isothermal DNA amplification monitoring in picoliter volumes using an optical fiber sensor33
A digital protein microarray for COVID-19 cytokine storm monitoring32
A robust and scalable active-matrix driven digital microfluidic platform based on printed-circuit board technology32
Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies32
Enzyme-based digital bioassay technology – key strategies and future perspectives32
A sample-to-answer, quantitative real-time PCR system with low-cost, gravity-driven microfluidic cartridge for rapid detection of SARS-CoV-2, influenza A/B, and human papillomavirus 16/1832
Review: tomographic imaging flow cytometry32
Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer32
A 3-dimensional microfluidic platform for modeling human extravillous trophoblast invasion and toxicological screening32
An integrated microfluidic system for early detection of sepsis-inducing bacteria32
In vitro assay for single-cell characterization of impaired deformability in red blood cells under recurrent episodes of hypoxia32
Microfluidic channel integrated with a lattice lightsheet microscopic system for continuous cell imaging31
Recent advances in integrated solid-state nanopore sensors31
Tuning particle inertial separation in sinusoidal channels by embedding periodic obstacle microstructures31
Microfluidic point-of-care device for detection of early strains and B.1.1.7 variant of SARS-CoV-2 virus31
A fully transparent, flexible PEDOT:PSS–ITO–Ag–ITO based microelectrode array for ECoG recording31
Recent progress on wearable point-of-care devices for ocular systems30
FertDish: microfluidic sperm selection-in-a-dish for intracytoplasmic sperm injection30
A simple and reversible glass–glass bonding method to construct a microfluidic device and its application for cell recovery30
A rapid nucleic acid concentration measurement system with large field of view for a droplet digital PCR microfluidic chip30
Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors29
A graphene oxide coated tapered microfiber acting as a super-sensor for rapid detection of SARS-CoV-229
Cancer drug screening with an on-chip multi-drug dispenser in digital microfluidics29
Immuno-biosensor on a chip: a self-powered microfluidic-based electrochemical biosensing platform for point-of-care quantification of proteins29
Microfluidic-based in vitro thrombosis model for studying microplastics toxicity29
Microfluidic electrical impedance assessment of red blood cell-mediated microvascular occlusion29
Recent methods of droplet microfluidics and their applications in spheroids and organoids29
Bacterial classification and antibiotic susceptibility testing on an integrated microfluidic platform29
Application of a gut–liver-on-a-chip device and mechanistic modelling to the quantitative in vitro pharmacokinetic study of mycophenolate mofetil29
3-D swimming microdrone powered by acoustic bubbles29
Postoperative evaluation of tumours based on label-free acoustic separation of circulating tumour cells by microstreaming28
Three-dimensional imaging on a chip using optofluidics light-sheet fluorescence microscopy28
Organoids/organs-on-a-chip: new frontiers of intestinal pathophysiological models28
Measuring barrier function in organ-on-chips with cleanroom-free integration of multiplexable electrodes28
Slip formation of a high-density droplet array for nucleic acid quantification by digital LAMP with a random-access system28
Emerging point-of-care technologies for anemia detection28
Engineering a deformation-free plastic spiral inertial microfluidic system for CHO cell clarification in biomanufacturing28
Oxygen control: the often overlooked but essential piece to create betterin vitrosystems28
Inertial focusing of circulating tumor cells in whole blood at high flow rates using the microfluidic CTCKey™ device for CTC enrichment27
Isolation and recovery of extracellular vesicles using optically-induced dielectrophoresis on an integrated microfluidic platform27
Deep imaging flow cytometry27
Predicting the fluid behavior of random microfluidic mixers using convolutional neural networks27
Assessing red blood cell deformability from microscopy images using deep learning27
Zigzag microchannel for rigid inertial separation and enrichment (Z-RISE) of cells and particles27
Digital microfluidics for biological analysis and applications27
Acoustic valves in microfluidic channels for droplet manipulation27
Tunnel dielectrophoresis for ultra-high precision size-based cell separation26
Microfluidic formation of crystal-like structures26
Technologies for measuring red blood cell deformability26
Multi-oscillation microrheology via acoustic force spectroscopy enables frequency-dependent measurements on endothelial cells at high-throughput26
Versatile acoustic manipulation of micro-objects using mode-switchable oscillating bubbles: transportation, trapping, rotation, and revolution26
Microfluidic droplet-based functional materials for cell manipulation26
Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants26
Integration of segmented microflow chemistry and online HPLC/MS analysis on a microfluidic chip system enabling enantioselective analyses at the nanoliter scale26
On-chip rapid drug screening of leukemia cells by acoustic streaming26
Machine learning assisted fast prediction of inertial lift in microchannels26
Flowmetering for microfluidics26
Size-tuneable isolation of cancer cells using stretchable inertial microfluidics25
Closed-loop feedback control of microfluidic cell manipulation via deep-learning integrated sensor networks25
Cell-sorting centrifugal microfluidic chip with a flow rectifier25
Microfluidic model with air-walls reveals fibroblasts and keratinocytes modulate melanoma cell phenotype, migration, and metabolism25
Disposable photonics for cost-effective clinical bioassays: application to COVID-19 antibody testing25
A microfluidic chip with a serpentine channel enabling high-throughput cell separation using surface acoustic waves25
On the acoustically induced fluid flow in particle separation systems employing standing surface acoustic waves – Part I25
Optimized design of obstacle sequences for microfluidic mixing in an inertial regime25
Recent advances in microfluidic devices for single-cell cultivation: methods and applications25
High-throughput and label-free enrichment of malignant tumor cells and clusters from pleural and peritoneal effusions using inertial microfluidics25
Automated sample-to-answer centrifugal microfluidic system for rapid molecular diagnostics of SARS-CoV-225
Stromal cell identity modulates vascular morphogenesis in a microvasculature-on-a-chip platform24
A fully integrated biomimetic microfluidic device for evaluation of sperm response to thermotaxis and chemotaxis24
Engineering inclined orientations of piezoelectric films for integrated acoustofluidics and lab-on-a-chip operated in liquid environments24
Bridging the academic–industrial gap: application of an oxygen and pH sensor-integrated lab-on-a-chip in nanotoxicology24
A microfluidic device enabling deterministic single cell trapping and release24
Human neuromuscular junction on micro-structured microfluidic devices implemented with a custom micro electrode array (MEA)24
Advances in droplet digital polymerase chain reaction on microfluidic chips24
Blood–brain barrier (BBB)-on-a-chip: a promising breakthrough in brain disease research24
High-throughput digital pathology via a handheld, multiplexed, and AI-powered ptychographic whole slide scanner24
Hotspots of root-exuded amino acids are created within a rhizosphere-on-a-chip24
Portable sample processing for molecular assays: application to Zika virus diagnostics24
A sequentially bioconjugated optofluidic laser for wash-out-free and rapid biomolecular detection24
A continuous flow PCR array microfluidic chip applied for simultaneous amplification of target genes of periodontal pathogens24
Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies24
A microphysiological early metastatic niche on a chip reveals how heterotypic cell interactions and inhibition of integrin subunit β3 impact breast cancer cell extravasation23
Surfactant-laden droplet size prediction in a flow-focusing microchannel: a data-driven approach23
High performance inkjet printed embedded electrochemical sensors for monitoring hypoxia in a gut bilayer microfluidic chip23
Microfluidic technologies for immunotherapy studies on solid tumours23
Deep learning detector for high precision monitoring of cell encapsulation statistics in microfluidic droplets23
Spatial trans-epithelial electrical resistance (S-TEER) integrated in organs-on-chips23
Label-free inertial-ferrohydrodynamic cell separation with high throughput and resolution23
Multi-parametric functional imaging of cell cultures and tissues with a CMOS microelectrode array23
The vascular niche in next generation microphysiological systems23
High-throughput injection molded microfluidic device for single-cell analysis of spatiotemporal dynamics23
Rapid isolation of circulating cancer associated fibroblasts by acoustic microstreaming for assessing metastatic propensity of breast cancer patients23
A microfluidic cartridge for fast and accurate diagnosis of Mycobacterium tuberculosis infections on standard laboratory equipment23
Microfluidic single-cell transcriptomics: moving towards multimodal and spatiotemporal omics23
Microfluidic quantum sensing platform for lab-on-a-chip applications23
Automated fluorescence quantification of extracellular vesicles collected from blood plasma using dielectrophoresis23
Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems22
Lab-in-a-pencil graphite: A 3D-printed microfluidic sensing platform for real-time measurement of antipsychotic clozapine level22
Development and future of droplet microfluidics22
Point-of-care microchip electrophoresis for integrated anemia and hemoglobin variant testing22
Emulating the chondrocyte microenvironment using multi-directional mechanical stimulation in a cartilage-on-chip22
Testing of drugs using human feto-maternal interface organ-on-chips provide insights into pharmacokinetics and efficacy22
Focused surface acoustic wave locally removes cells from culture surface22
Microfluidics for antibiotic susceptibility testing22
Parallel multistep digital analysis SlipChip demonstrated with the quantification of nucleic acid by digital LAMP-CRISPR22
Small intestinal sampling capsule for inflammatory bowel disease type detection and management22
Practical microcircuits for handheld acoustofluidics22
Generation of flow and droplets with an ultra-long-range linear concentration gradient22
An “occlusive thrombosis-on-a-chip” microfluidic device for investigating the effect of anti-thrombotic drugs22
Self-aligned sequential lateral field non-uniformities over channel depth for high throughput dielectrophoretic cell deflection22
An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing22
A polymer index-matched to water enables diverse applications in fluorescence microscopy22
Multiplex amplification of target genes of periodontal pathogens in continuous flow PCR microfluidic chip22
Will the next generation of chemical plants be in miniaturized flow reactors?22
Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip22
Dosage-controlled intracellular delivery mediated by acoustofluidics for lab on a chip applications22
Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device22
3D-printed capillaric ELISA-on-a-chip with aliquoting21
Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation21
A microfluidic device and instrument prototypes for the detection of Escherichia coli in water samples using a phage-based bioluminescence assay21
Recent advances in gold electrode fabrication for low-resource setting biosensing21
Biohybrid sensor for odor detection21
Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-on-chips21
Quantitative particle agglutination assay for point-of-care testing using mobile holographic imaging and deep learning21
Integrated microfluidic platform with electrohydrodynamic focusing and a carbon-nanotube-based field-effect transistor immunosensor for continuous, selective, and label-free quantification of bacteria21
Recent advances in microfluidics-based cell migration research21
Programmable motion control and trajectory manipulation of microparticles through tri-directional symmetrical acoustic tweezers21
A plantar wearable pressure sensor based on hybrid lead zirconate-titanate/microfibrillated cellulose piezoelectric composite films for human health monitoring21
A critical review of microfluidic systems for CRISPR assays21
An epidermal wearable microfluidic patch for simultaneous sampling, storage, and analysis of biofluids with counterion monitoring21
A photofabricated honeycomb micropillar array for loss-free trapping of microfluidic droplets and application to digital PCR20
Bio-inspired fractal textile device for rapid sweat collection and monitoring20
Extraction of small extracellular vesicles by label-free and biocompatible on-chip magnetic separation20
Flexural wave-based soft attractor walls for trapping microparticles and cells20
Scaffold-free generation of heterotypic cell spheroids using acoustofluidics20
Microfluidic solutions for biofluids handling in on-skin wearable systems20
Go with the flow: modeling unique biological flows in engineeredin vitroplatforms20
Monitoring the effects of chemical stimuli on live cells with metasurface-enhanced infrared reflection spectroscopy20
Label-free detection and enumeration of rare circulating tumor cells by bright-field image cytometry and multi-frame image correlation analysis20
3D micromixer for nanoliposome synthesis: a promising advance in high mass productivity20
On-chip perivascularnichesupporting stemness of patient-derived glioma cells in a serum-free, flowable culture20
Sheathless and high-throughput elasto-inertial bacterial sorting for enhancing molecular diagnosis of bloodstream infection20
Simplifying the complex: accessible microfluidic solutions for contemporary processes within in vitro diagnostics20
IL-2 secretion-based sorting of single T cells using high-throughput microfluidic on-cell cytokine capture20
A method of sequential liquid dispensing for the multiplexed genetic diagnosis of viral infections in a microfluidic device20
Microfluidic recapitulation of circulating tumor cell–neutrophil clusters via double spiral channel-induced deterministic encapsulation20
Lateral flow device for water fecal pollution assessment: from troubleshooting of its microfluidics using bioluminescence to colorimetric monitoring of generic Escherichia coli20
Mechanotransduction-on-chip: vessel-chip model of endothelial YAP mechanobiology reveals matrix stiffness impedes shear response20
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