OOIR: Observatory of International Research

Papers

(The TQCC of Tuberculosis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Pathology of TB/COVID-19 Co-Infection: The phantom menace	69
Drug resistance, fitness and compensatory mutations in Mycobacterium tuberculosis	51
Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity	48
Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection	43
An efficient deep learning-based framework for tuberculosis detection using chest X-ray images	38
A new resource on artificial intelligence powered computer automated detection software products for tuberculosis programmes and implementers	33
Current advances in the clinical development of anti-tubercular agents	33
Mechanisms and detection methods of Mycobacterium tuberculosis rifampicin resistance: The phenomenon of drug resistance is complex	31
Targeted next generation sequencing directly from sputum for comprehensive genetic information on drug resistant Mycobacterium tuberculosis	26
Highly transmitted M. tuberculosis strains are more likely to evolve MDR/XDR and cause outbreaks, but what makes them highly transmitted?	20
NIX-mediated mitophagy regulate metabolic reprogramming in phagocytic cells during mycobacterial infection	19
The immunological architecture of granulomatous inflammation in central nervous system tuberculosis	18
Xpert MTB/RIF ultra for the diagnosis of tuberculous meningitis: A diagnostic accuracy study from India	18
Metabolic profiles of multidrug resistant and extensively drug resistant Mycobacterium tuberculosis unveiled by metabolomics	18
Cough-independent production of viable Mycobacterium tuberculosis in bioaerosol	18
Laboratory development of a simple stool sample processing method diagnosis of pediatric tuberculosis using Xpert Ultra	17
Mycobacterium bovis and you: A comprehensive look at the bacteria, its similarities to Mycobacterium tuberculosis, and its relationship with human disease	17
Steroid hormone modulates the production of cathelicidin and human β-defensins in lung epithelial cells and macrophages promoting Mycobacterium tuberculosis killing	17
The use of thalidomide to treat children with tuberculosis meningitis: A review	16
Mycobacterial MCE proteins as transporters that control lipid homeostasis of the cell wall	16
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease	16
Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis	16
Dry powder inhalers of antitubercular drugs	15
Nontuberculous mycobacteria in the environment	15
Prevalence of Mycobacterium bovis in milk on dairy cattle farms: An international systematic literature review and meta-analysis	15

Activation of hypoxia-inducible factor 1 (Hif-1) enhanced bactericidal effects of macrophages to Mycobacterium tuberculosis	15
HDAC3 inhibitor RGFP966 controls bacterial growth and modulates macrophage signaling during Mycobacterium tuberculosis infection	14
Ferroptosis-related gene SOCS1, a marker for tuberculosis diagnosis and treatment, involves in macrophage polarization and facilitates bone destruction in tuberculosis	14
Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in the detection of drug resistance of Mycobacterium tuberculosis in re-treated patients	14
Immunologic and imaging signatures in post tuberculosis lung disease	14
Diagnostic performance of real time PCR and MALDI-TOF in the detection of nontuberculous mycobacteria from clinical isolates	13
Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals	13
Point-of-care detection of tuberculosis using magnetoresistive biosensing chip	13
Circ_0001490/miR-579-3p/FSTL1 axis modulates the survival of mycobacteria and the viability, apoptosis and inflammatory response in Mycobacterium tuberculosis-infected macrophages	13
A multi-targeting pre-clinical candidate against drug-resistant tuberculosis	13
Identification of a novel biomarker based on lymphocyte count, albumin level, and TBAg/PHA ratio for differentiation between active and latent tuberculosis infection in Japan	13
The effect of micro-nutrients on malnutrition, immunity and therapeutic effect in patients with pulmonary tuberculosis: A systematic review and meta‐analysis of randomised controlled trials	12
Cerebrospinal fluid AFB smear in adults with tuberculous meningitis: A systematic review and diagnostic test accuracy meta-analysis	12
Inhalable particles containing isoniazid and rifabutin as adjunct therapy for safe, efficacious and relapse-free cure of experimental animal tuberculosis in one month	12
Oldest evidence of tuberculosis in Argentina: A multidisciplinary investigation in an adult male skeleton from Saujil, Tinogasta, Catamarca (905–1030 CE)	12
A 10-gene biosignature of tuberculosis treatment monitoring and treatment outcome prediction	11
Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics	11
Immunomodulation by epigenome alterations in Mycobacterium tuberculosis infection	11
Identification of differentially expressed lncRNAs as potential plasma biomarkers for active tuberculosis	11
Environmental risk of nontuberculous mycobacterial infection: Strategies for advancing methodology	11
Tuberculosis and autoimmunity: Common features	11
Towards the development of subunit vaccines against tuberculosis: The key role of adjuvant	11
An accurate artificial intelligence system for the detection of pulmonary and extra pulmonary Tuberculosis	11
Human leukocyte antigen associations with protection against tuberculosis infection and disease in human immunodeficiency virus-1 infected individuals, despite household tuberculosis exposure and immu	11
Preclinical murine models to study lung infection with Mycobacterium abscessus complex	10
Challenges and a potential solution to perform drug susceptibility testing of omadacycline against nontuberculous mycobacteria	10
The TB vaccine development pathway – An innovative approach to accelerating global TB vaccine development	10
Alterations in the nasopharyngeal microbiota associated with active and latent tuberculosis	10
Proteomic profile of vitreous in patients with tubercular uveitis	10
Molecular analysis of streptomycin-resistance associating genes in Mycobacterium tuberculosis isolates from Nepal	10
The diagnostic value of T cell spot test and adenosine deaminase in pleural effusion for tuberculous pleurisy: A systematic review and meta-analysis	9
THP-1 cell line model for tuberculosis: A platform for in vitro macrophage manipulation	9
Verification of tuberculosis infection among Vác mummies (18th century CE, Hungary) based on lipid biomarker profiling with a new HPLC-HESI-MS approach	9
Supplementation of sputum cultures with culture filtrate to detect tuberculosis in a cross-sectional study of HIV-infected individuals	9
Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket	9
Transient, inhaled gene therapy with gamma interferon mitigates pathology induced by host response in a mouse model of tuberculosis	8
Transmission of Mycobacterium tuberculosis presenting unusually high discordance between genotypic and phenotypic resistance to rifampicin in an endemic tuberculosis setting	8
Serodiagnostic evaluation of fusion proteins from multiple antigens of Mycobacterium tuberculosis for active TB	8
Investigation on the cause of recurrent tuberculosis in a rural area in China using whole-genome sequencing: A retrospective cohort study	8
Optimizing liquefaction and decontamination of sputum for DNA extraction from Mycobacterium tuberculosis	8
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis	8
Human monocyte-derived macrophage responses to M. tuberculosis differ by the host's tuberculosis, diabetes or obesity status, and are enhanced by rapamycin	8
Ubiquitous and multifaceted: SIT53 spoligotype does not correlate with any particular family of Mycobacterium tuberculosis	8
Modulation of the M. tuberculosis cell envelope between replicating and non-replicating persistent bacteria	8
Performance of GeneXpert ultra in the diagnosis of Tuberculous Cervical lymphadenitis in formalin fixed paraffin embedded tissues	8
A whole-genome sequencing study of an X-family tuberculosis outbreak focus on transmission chain along 25 years	7
Evaluating the diversity of circulating natural killer cells between active tuberculosis and latent tuberculosis infection	7
Role of hematopoietic cells in Mycobacterium tuberculosis infection	7
Accuracy of the Truenat MTB-RIF Dx assay for detection of rifampicin resistance-associated mutations	7
Identification of anti-lipoarabinomannan antibodies against mannan core and their effects on phagocytosis of mycobacteria by human neutrophils	7

A highly rifampicin resistant Mycobacterium tuberculosis strain emerging in Southern Brazil	7
Differential effects of asymptomatic Ascaris lumbricoides, Schistosoma mansoni or hook worm infection on the frequency and TGF-beta-producing capacity of regulatory T cells during active tuberculosis	7
Nicotine promotes the intracellular growth of Mycobacterium tuberculosis in epithelial cells	7
A rare case of calvarial tuberculosis from the Avar Age (8th century CE) cemetery of Kaba–Bitózug (Hajdú-Bihar county, Hungary) – Pathogenesis and differential diagnostic aspects	7
Effects of tafenoquine against active, dormant and resistant Mycobacterium tuberculosis	7
Cerebrospinal fluid IL-1β is elevated in tuberculous meningitis patients but not associated with mortality	7
Mab2780c, a TetV-like efflux pump, confers high-level spectinomycin resistance in mycobacterium abscessus	7
Risk factors associated with large clusters of tuberculosis patients determined by whole-genome sequencing in a high-tuberculosis-burden country	7
Deep whole-genome sequencing reveals no evidence for heteroresistance influencing treatment outcomes among drug-susceptible tuberculosis patients	7
Characteristics of plasma exosomes in drug-resistant tuberculosis patients	6
MTS1338 in Mycobacterium tuberculosis promotes detoxification of reactive oxygen species under oxidative stress	6
Immunogenicity and protection against Mycobacterium avium with a heterologous RNA prime and protein boost vaccine regimen	6
The association between vitamin D deficiency and extrapulmonary tuberculosis: Case-control study	6
High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course	6
Evaluation of a new assay for nontuberculous mycobacteria species identification in diagnostic material and cultures	6
Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing	6
Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses	6
Pyrazinamide resistance and pncA mutations in drug resistant Mycobacterium tuberculosis clinical isolates from Myanmar	6
Determining the diagnostic potential of Truenat MTB Plus for Tubercular lymphadenitis and detection of drug resistance and a comparison with GeneXpert Ultra	6
Identification of novel salivary candidate protein biomarkers for tuberculosis diagnosis: A preliminary biomarker discovery study	6
Insights into the molecular pathogenesis of ocular tuberculosis	5
Rv1258c acts as a drug efflux pump and growth controlling factor in Mycobacterium tuberculosis	5
Activating transcription factor 3 protects alveolar epithelial type II cells from Mycobacterium tuberculosis infection-induced inflammation	5
In vitro activity of tetracycline analogs against multidrug-resistant and extensive drug resistance clinical isolates of Mycobacterium tuberculosis	5
Performance of a simple flow cytometric assay in diagnosing active tuberculosis	5
Nanotechnology and tuberculosis: An old disease with new treatment strategies	5
Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes	5
Raman spectroscopy and machine learning-based optical probe for tuberculosis diagnosis via sputum	5
Clofazimine as a comparator for preclinical efficacy evaluations of experimental therapeutics against pulmonary M. abscessus infection in mice	5
Mycobacterium abscessus drug discovery using machine learning	5
Potential biomarker enhancing the activity of tuberculosis, hsa-miR-346	5
Development of a limited sampling strategy for the estimation of isoniazid exposure considering N-acetyltransferase 2 genotypes in Korean patients with tuberculosis	5
Evaluation of a booster tuberculosis vaccine containing mycobacterial DNA-binding protein 1 and CpG oligodeoxynucleotide G9.1 using a Guinea pig model that elicits immunity to Bacillus Calmette–Guérin	5
Novel TB smear microscopy automation system in detecting acid-fast bacilli for tuberculosis – A multi-center double blind study	5
Culture independent markers of nontuberculous mycobacterial (NTM) lung infection and disease in the cystic fibrosis airway	5
LIODetect®TB-ST: Evaluation of novel blood test for a rapid diagnosis of active pulmonary and extra-pulmonary tuberculosis in IGRA confirmed patients	5
Evaluation of genotype MTBDRplus V2 and genotype MTBDRsl V2 for the diagnosis of extrapulmonary tuberculosis in India	5
Impact of diabetes mellitus on tuberculosis epidemiology in Indonesia: A mathematical modeling analysis	5
Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZ	5
Utility of the Whole Genome Sequencing based methodologies in routine European tuberculosis reference laboratory network setting	5
Knockout of MRA_1916 in Mycobacterium tuberculosis H37Ra affects its growth, biofilm formation, survival in macrophages and in mice	5
Significance of the chemokine CXCL10 and human beta-defensin-3 as biomarkers of pulmonary tuberculosis	5
Stimulated expression of ELR+ chemokines, VEGFA and TNF-AIP3 promote mycobacterial dissemination in extrapulmonary tuberculosis patients and Cavia porcellus model of tuberculosis	5
Characterization of probes associated with rifampicin resistance in M.tuberculosis detected by GenXpert from a national reference laboratory at Chennai	5
Population structure of multidrug-resistant Mycobacterium tuberculosis clinical isolates in Colombia	5
Evaluation of CSF pyrosequencing to diagnose tuberculous meningitis: A retrospective diagnostic accuracy study	5
Serum proteomics analysis for differentiation among Mycobacterium tuberculosis infection categories	5
NF–κB–mediated TET2–dependent TNF promoter demethylation drives Mtb–upregulation TNF expression in macrophages	5
Host biomarkers other than interferon gamma in QFT-TB supernatants for identifying active tuberculosis	5
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster	5