OOIR: Observatory of International Research

Papers

(The TQCC of Tuberculosis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Enhanced efficacy of BCG vaccine formulated in adjuvant is dependent on IL-17A expression	62
Domestic pigs experimentally infected with Mycobacterium bovis and Mycobacterium tuberculosis exhibit different disease outcomes	50
A novel chemogenomic discovery platform identifies bioactive hits with rapid bactericidal activity against Mycobacteroides Abscessus	34
Upper Paleolithic tuberculosis: A probable case illustrated by paleoimaging methods (Azilian site of Les Iboussières, France)	24
Preclinical tests for salicylhydrazones derivatives to explore their potential for new antituberculosis agents	23
Mycobacterium bovis mutant in the virulence factors PhoP, ESAT-6 and CFP-10 persisted in mouse organs after a year post-vaccination	23
Biofilms in tuberculosis: What have we learnt in the past decade and what is still unexplored?	22
Editorial Board	22
Sensitive lipid biomarker detection for tuberculosis in late Neanderthal skeletons from Subalyuk Cave, Hungary	21
Editorial Board	20
The Rv3874-Rv3875 chimeric protein shows a promiscuous serodiagnostic potential for tuberculosis	19
The use of Mycobacterium tuberculosis H37Ra-infected immunocompetent mice as an in vivo model of persisters	19
Tuberculosis and autoimmunity: Common features	18
Exhaled breath analysis: A promising triage test for tuberculosis in young children	18
Immunogenicity and protection against Mycobacterium avium with a heterologous RNA prime and protein boost vaccine regimen	18
Predictive biomarkers for latent Mycobacterium tuberculosis infection	17
IgG antibody response to Mycobacterium tuberculosis curli pili (MTP) in people from different geographical regions in Sub-Saharan Africa	16
Editorial Board	15
The evaluation of Phenylalanine-tRNA ligase beta unit (PheT), as a potential target in Mycobacterium abscessus	15
Utilization of Truenat chips in defining XDR, pre-XDR and MDR in tuberculous meningitis	15
Immunomodulation by epigenome alterations in Mycobacterium tuberculosis infection	14
The immunomodulatory effects of Mesenchymal stem cells on THP-1-derived macrophages against Mycobacterium tuberculosis H37Ra infection	14
Editorial Board	14
Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZ	14
GlfT1 down-regulation affects Mycobacterium tuberculosis biofilm formation and its in-vitro and in-vivo survival	14

An immunocompetent rat model of Mycobacterium abscessus multinodular granulomatous lung infection	13
Cerebrospinal fluid AFB smear in adults with tuberculous meningitis: A systematic review and diagnostic test accuracy meta-analysis	13
Oldest evidence of tuberculosis in the Mediterranean islands: From the mainland to Cyprus	12
In-vivo expressed mycobacterial transcripts as diagnostic targets for pulmonary tuberculosis	12
Low performance of interferon gamma release assay Quantiferon-TB gold coupled or not with Pst1/3/lipoglycan humoral detection to predict Mycobacterium tuberculosis complex disease in a low-burden area	12
Macrophage-targeted versus free calcitriol as host-directed adjunct therapy against Mycobacterium tuberculosis infection in mice is bacteriostatic and mitigates tissue pathology	12
Nanotechnology and tuberculosis: An old disease with new treatment strategies	12
Assessment of DNA aptamers targeting GlcB and HspX antigens for application in the diagnosis of abdominal tuberculosis	12
Characterizing in vivo loss of virulence of an HN878 Mycobacterium tuberculosis isolate from a genetic duplication event	11
Editorial Board	11
"Tuberculosis on the spot" – Discussion of a probable sternal tuberculosis from a late medieval cemetery from Hungary	10
Proteome and immunogenicity differences in BCG Pasteur ATCC 35734 and its derivative, the vaccine candidate BCGΔBCG1419c during planktonic growth in 7H9 and Proskauer Beck media	10
Epidemiology and molecular characterization of Mycobacterium tuberculosis including a drug-resistant strain associated with mortality of Asian elephants in Nepal 2019–2022	9
Serodiagnosis of paucibacillary and multibacillary leprosy using a recombinant chimeric protein composed of specific B-cell epitopes derived from Mycobacterium leprae proteins	9
Leprosy: The age-old companion of humans – Re-evaluation and comparative analysis of Avar-period cases with Hansen's disease from the Danube-Tisza Interfluve, Hungary	9
Culture independent markers of nontuberculous mycobacterial (NTM) lung infection and disease in the cystic fibrosis airway	9
An accurate artificial intelligence system for the detection of pulmonary and extra pulmonary Tuberculosis	9
Evaluation of immune profiles associated with control of mycobacterial growth in systemic lupus erythematosus (SLE) patients	9
Construction and expression of multi-stage antigen fusion protein RPC4 vaccine for Mycobacterium tuberculosis and its immunogenicity analysis in combination with adjuvant DIMQ	8
Host urinary biomarkers in HIV positive and HIV negative patients with tubercular uveitis and other uveitic diseases	8
Microneedle-mediated intradermal delivery of Bacille Calmette-Guérin (BCG) vaccines for single-dose tuberculosis vaccination	8
Stimulated expression of ELR+ chemokines, VEGFA and TNF-AIP3 promote mycobacterial dissemination in extrapulmonary tuberculosis patients and Cavia porcellus model of tuberculosis	8
Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response	8
Transmission of drug-resistant Mycobacterium tuberculosis isolates between Finnish- and foreign-born cases, 2014–2021: A molecular epidemiological study	8
Replication and transmission features of two experimental vaccine candidates against bovine tuberculosis subcutaneously administrated in a murine model	8
Activating transcription factor 3 protects alveolar epithelial type II cells from Mycobacterium tuberculosis infection-induced inflammation	8
Effect of Metformin on systemic chemokine responses during anti-tuberculosis chemotherapy	7
Ferroptosis-related gene SOCS1, a marker for tuberculosis diagnosis and treatment, involves in macrophage polarization and facilitates bone destruction in tuberculosis	7
Identification of anti-lipoarabinomannan antibodies against mannan core and their effects on phagocytosis of mycobacteria by human neutrophils	7
Editorial Board	7
Rv3371, a triacylglycerol synthase promotes survival of Mycobacterium tuberculosis in the host through its contributions to redox homeostasis and propionate detoxification	7
Franz Tappeiner (1816–1902) and his pioneering studies on tuberculosis	7
Adaptation to the intracellular environment of primary human macrophages influences drug susceptibility of Mycobacterium tuberculosis	7
Towards the development of subunit vaccines against tuberculosis: The key role of adjuvant	7
Editorial Board	7
Knockout of MRA_1916 in Mycobacterium tuberculosis H37Ra affects its growth, biofilm formation, survival in macrophages and in mice	7
Increasing circulation of multi-drug resistant tuberculosis strains in Buryatia, high-burden and ethnically diverse region in the Russian Far East	7
Mycobacterium bovis BCG dodecin gene codes a functional protein despite of a start codon mutation	7
Assessment of transcriptional markers for the differentiation of Mycobacterium mungi infection status in free-ranging banded mongoose (Mungos mungo)	7
Lumbosacral tuberculosis, a rare manifestation of Pott's disease – How identified human skeletons from the pre-antibiotic era can be used as reference cases to establish a palaeopathological diagnosis	7
METTL3-deficiency m6A-dependently degrades MALAT1 to suppress NLRP3-mediated pyroptotic cell death and inflammation in Mycobacterium tuberculosis (H37Ra strain)-infected mouse macrophages	7
Analysis and comparison of image processing and artificial intelligence algorithms to detect AFB in pulmonary tuberculosis images	7
Steroid immune responsive gene regulation in Mycobacterium tuberculosis infection in vitro	7
Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing	7
Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens	7
Down-regulation of GAS5 has diagnostic value for tuberculosis and regulates the inflammatory response in mycobacterium tuberculosis infected THP-1 cells	6
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster	6
Response to “Prevalence of non-tuberculous mycobacteria by Line-Probe Assay”	6
Ex-vivo immunophenotyping and high dimensionality UMAP analysis of leucocyte subsets in tuberculous lymphadenitis	6
Flow cytometry-based method using diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease	6

Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease	6
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis	6
The paradoxes of Mycobacterium tuberculosis molecular evolution and consequences for the inference of tuberculosis emergence date	6
Detection of Mycobacterium tuberculosis complex in saliva by quantitative PCR: A potential alternative specimen for pulmonary tuberculosis diagnosis	6
Analysis of genetic characteristics associated with reduced bedaquiline susceptibility in multidrug-resistant Mycobacterium tuberculosis	6
Growth-inhibitory effects of tris-(1,10-phenanthroline) iron (II) against Mycobacterium tuberculosis in vitro and in vivo	6
Computational drug repositioning identifies niclosamide and tribromsalan as inhibitors of Mycobacterium tuberculosis and Mycobacterium abscessus	6
Mycobacterium abscessus drug discovery using machine learning	6
Deferiprone-gallium-protoporphyrin (IX): A promising treatment modality against Mycobacterium abscessus	6
Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections	6
Editorial Board	6
The PPE2 protein of Mycobacterium tuberculosis is secreted during infection and facilitates mycobacterial survival inside the host	6
Mechanisms and detection methods of Mycobacterium tuberculosis rifampicin resistance: The phenomenon of drug resistance is complex	6
Genomic comparison of two strains of Mycobacterium avium subsp. paratuberculosis with contrasting pathogenic phenotype	6
Utility of pleural fluid-derived extracellular vesicles as a source of Mycobacterium tuberculosis antigens MPT51 and MPT64 for pleural TB diagnosis: a proof-of-concept study	5
Differences in biomarker concentrations in serum and urine of patients with Ocular Tuberculosis – A prospective descriptive study	5
Lysosomal enzymes and the oxygen burst capability of monocyte-derived macrophages in active drug-resistant tuberculosis patients in relation to cell attachment	5
Functional analysis of genetic mutations in ddn and fbiA linked to delamanid resistance in rifampicin-resistant Mycobacterium tuberculosis	5
Inability of the BCG vaccine to protect mice of the H2f haplotype at advanced stages of TB infection is associated with defective CD4+ T-cell activation in spleen	5
Analysis of T-lymphocyte subsets and risk factors in children with tuberculosis	5
Mab2780c, a TetV-like efflux pump, confers high-level spectinomycin resistance in mycobacterium abscessus	5
Editorial Board	5
Identification of BMVC-8C3O as a novel Pks13 inhibitor with anti-tuberculosis activity	5
Evaluating the effects of Cyclosporine A immunosuppression on Mycobacterial infection by inhaling of Cyclosporine A administrated BALB/c mice with live Bacillus Calmette Guérin	5
The impact of genotype on the phenotype of Mycobacterium tuberculosis ΔsufR mutants	5
Raman spectroscopy and machine learning-based optical probe for tuberculosis diagnosis via sputum	5
Evaluation of AAICare®-TB sequence analysis tool for accurate diagnosis of drug-resistant tuberculosis: A comparative study with TB-Profiler and Mykrobe	5
Synergistic role of Mycobacterium indicus pranii and human beta Defensin-2 as adjunctive therapy against Mycobacterium tuberculosis	5
The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses	5
Treatment of tuberculous meningitis: Overdue for concerted action	5