Tuberculosis

Article	Citations
Pathology of TB/COVID-19 Co-Infection: The phantom menace	50
Drug resistance, fitness and compensatory mutations in Mycobacterium tuberculosis	43
Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection	37
Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity	36
Global tuberculosis research and its future prospects	29
A new resource on artificial intelligence powered computer automated detection software products for tuberculosis programmes and implementers	28
Current advances in the clinical development of anti-tubercular agents	27
Recent advances in the synthesis of Quinazoline analogues as Anti-TB agents	26
Mechanisms and detection methods of Mycobacterium tuberculosis rifampicin resistance: The phenomenon of drug resistance is complex	23
An efficient deep learning-based framework for tuberculosis detection using chest X-ray images	23
Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9	21
Diagnosis of active tuberculosis and latent tuberculosis infection based on Raman spectroscopy and surface-enhanced Raman spectroscopy	21
Whole genome enrichment approach for rapid detection of Mycobacterium tuberculosis and drug resistance-associated mutations from direct sputum sequencing	21
Drug repurposing: Fusidic acid as a potential inhibitor of M. tuberculosis FtsZ polymerization – Insight from DFT calculations, molecular docking and molecular dynamics simulations	20
Targeted next generation sequencing directly from sputum for comprehensive genetic information on drug resistant Mycobacterium tuberculosis	19
A review on bovine tuberculosis in India	19
Tuberculosis: A granulomatous disease mediated by epigenetic factors	18
The immunological architecture of granulomatous inflammation in central nervous system tuberculosis	17
Xpert MTB/RIF ultra for the diagnosis of tuberculous meningitis: A diagnostic accuracy study from India	17
Contributing risk factors towards the prevalence of multidrug-resistant tuberculosis in Malaysia: A systematic review	16
Pathogenesis of ocular tuberculosis: New observations and future directions	16
Cough-independent production of viable Mycobacterium tuberculosis in bioaerosol	16
NIX-mediated mitophagy regulate metabolic reprogramming in phagocytic cells during mycobacterial infection	15
Metabolic profiles of multidrug resistant and extensively drug resistant Mycobacterium tuberculosis unveiled by metabolomics	15
Increased transmissibility of Russian successful strain Beijing B0/W148 of Mycobacterium tuberculosis: Indirect clues from history and demographics	15

Highly transmitted M. tuberculosis strains are more likely to evolve MDR/XDR and cause outbreaks, but what makes them highly transmitted?	15
Diagnostic value of pleural fluid T-SPOT for tuberculous pleurisy: An updated meta-analysis	14
Laboratory development of a simple stool sample processing method diagnosis of pediatric tuberculosis using Xpert Ultra	14
NOTCH1 and DLL4 are involved in the human tuberculosis progression and immune response activation	14
Toward a point-of-care diagnostic for specific detection of Mycobacterium tuberculosis from sputum samples	14
Identification of a novel biomarker based on lymphocyte count, albumin level, and TBAg/PHA ratio for differentiation between active and latent tuberculosis infection in Japan	13
Whole-genome sequencing and Mycobacterium tuberculosis: Challenges in sample preparation and sequencing data analysis	13
Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals	13
Dry powder inhalers of antitubercular drugs	13
Mycobacterial MCE proteins as transporters that control lipid homeostasis of the cell wall	13
Ferroptosis-related gene SOCS1, a marker for tuberculosis diagnosis and treatment, involves in macrophage polarization and facilitates bone destruction in tuberculosis	12
Tuberculosis in elephants: Origins and evidence of interspecies transmission	12
Steroid hormone modulates the production of cathelicidin and human β-defensins in lung epithelial cells and macrophages promoting Mycobacterium tuberculosis killing	12
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease	12
Activation of hypoxia-inducible factor 1 (Hif-1) enhanced bactericidal effects of macrophages to Mycobacterium tuberculosis	12
Three promising antimycobacterial medicinal plants reviewed as potential sources of drug hit candidates against multidrug-resistant tuberculosis	12
Point-of-care detection of tuberculosis using magnetoresistive biosensing chip	11
Diagnostic performance of real time PCR and MALDI-TOF in the detection of nontuberculous mycobacteria from clinical isolates	11
Pulmonary mucosal immunity mediated through CpG provides adequate protection against pulmonary Mycobacterium tuberculosis infection in the mouse model. A role for type I interferon	11
Prevalence of Mycobacterium bovis in milk on dairy cattle farms: An international systematic literature review and meta-analysis	11
Mycobacterium bovis and you: A comprehensive look at the bacteria, its similarities to Mycobacterium tuberculosis, and its relationship with human disease	11
HDAC3 inhibitor RGFP966 controls bacterial growth and modulates macrophage signaling during Mycobacterium tuberculosis infection	11
The use of thalidomide to treat children with tuberculosis meningitis: A review	11
A multi-targeting pre-clinical candidate against drug-resistant tuberculosis	11
HIV and tuberculosis: A historical perspective on conflicts and challenges	11
A 10-gene biosignature of tuberculosis treatment monitoring and treatment outcome prediction	10
Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis	10
Oldest evidence of tuberculosis in Argentina: A multidisciplinary investigation in an adult male skeleton from Saujil, Tinogasta, Catamarca (905–1030 CE)	10
Immunomodulation by epigenome alterations in Mycobacterium tuberculosis infection	10
Circ_0001490/miR-579-3p/FSTL1 axis modulates the survival of mycobacteria and the viability, apoptosis and inflammatory response in Mycobacterium tuberculosis-infected macrophages	10
The effect of micro-nutrients on malnutrition, immunity and therapeutic effect in patients with pulmonary tuberculosis: A systematic review and meta‐analysis of randomised controlled trials	10
Ocular tuberculosis epidemiology, clinic features and diagnosis: A brief review	9
Verification of tuberculosis infection among Vác mummies (18th century CE, Hungary) based on lipid biomarker profiling with a new HPLC-HESI-MS approach	9
Molecular analysis of streptomycin-resistance associating genes in Mycobacterium tuberculosis isolates from Nepal	9
Immunologic and imaging signatures in post tuberculosis lung disease	9
The TB vaccine development pathway – An innovative approach to accelerating global TB vaccine development	9
Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in the detection of drug resistance of Mycobacterium tuberculosis in re-treated patients	8
Tuberculosis and autoimmunity: Common features	8
Identification of differentially expressed lncRNAs as potential plasma biomarkers for active tuberculosis	8
Cerebrospinal fluid AFB smear in adults with tuberculous meningitis: A systematic review and diagnostic test accuracy meta-analysis	8
Inhalable particles containing isoniazid and rifabutin as adjunct therapy for safe, efficacious and relapse-free cure of experimental animal tuberculosis in one month	8
An accurate artificial intelligence system for the detection of pulmonary and extra pulmonary Tuberculosis	8
Modulation of the M. tuberculosis cell envelope between replicating and non-replicating persistent bacteria	8
Designing fusion molecules from antigens of Mycobacterium tuberculosis for detection of multiple antibodies in plasma of TB patients	8
A machine learning-based framework for Predicting Treatment Failure in tuberculosis: A case study of six countries	8
QuantiFERON-TB Gold Plus combined with HBHA-Induced IFN-γ release assay improves the accuracy of identifying tuberculosis disease status	8
A highly rifampicin resistant Mycobacterium tuberculosis strain emerging in Southern Brazil	7
Investigation on the cause of recurrent tuberculosis in a rural area in China using whole-genome sequencing: A retrospective cohort study	7
Differential effects of asymptomatic Ascaris lumbricoides, Schistosoma mansoni or hook worm infection on the frequency and TGF-beta-producing capacity of regulatory T cells during active tuberculosis	7
Human leukocyte antigen associations with protection against tuberculosis infection and disease in human immunodeficiency virus-1 infected individuals, despite household tuberculosis exposure and immu	7

Nicotine promotes the intracellular growth of Mycobacterium tuberculosis in epithelial cells	7
A rare case of calvarial tuberculosis from the Avar Age (8th century CE) cemetery of Kaba–Bitózug (Hajdú-Bihar county, Hungary) – Pathogenesis and differential diagnostic aspects	7
Cerebrospinal fluid IL-1β is elevated in tuberculous meningitis patients but not associated with mortality	7
Glibenclamide alters interleukin-8 and interleukin-1β of primary human monocytes from diabetes patients against Mycobacterium tuberculosis infection	7
Serodiagnostic evaluation of fusion proteins from multiple antigens of Mycobacterium tuberculosis for active TB	7
Challenges and a potential solution to perform drug susceptibility testing of omadacycline against nontuberculous mycobacteria	7
Human monocyte-derived macrophage responses to M. tuberculosis differ by the host's tuberculosis, diabetes or obesity status, and are enhanced by rapamycin	7
Alterations in the nasopharyngeal microbiota associated with active and latent tuberculosis	7
Adults with Mycobacterium tuberculosis infection and pre-diabetes have increased levels of QuantiFERON interferon-gamma responses	7
Proteomic profile of vitreous in patients with tubercular uveitis	7
Transmission of Mycobacterium tuberculosis presenting unusually high discordance between genotypic and phenotypic resistance to rifampicin in an endemic tuberculosis setting	7
Alternative biomarkers for classification of latent tuberculosis infection status in pregnant women with borderline Quantiferon plus results	7
Accuracy of the Truenat MTB-RIF Dx assay for detection of rifampicin resistance-associated mutations	7
Identification of anti-lipoarabinomannan antibodies against mannan core and their effects on phagocytosis of mycobacteria by human neutrophils	7
Towards the development of subunit vaccines against tuberculosis: The key role of adjuvant	6
Optimizing liquefaction and decontamination of sputum for DNA extraction from Mycobacterium tuberculosis	6
Role of hematopoietic cells in Mycobacterium tuberculosis infection	6
Performance of Xpert MTB/RIF in diagnosis of lymphatic tuberculosis from fresh and formaldehyde-fixed and paraffin embedded lymph nodes	6
Deep whole-genome sequencing reveals no evidence for heteroresistance influencing treatment outcomes among drug-susceptible tuberculosis patients	6
The Many Hosts of Mycobacteria 8 (MHM8): A conference report	6
THP-1 cell line model for tuberculosis: A platform for in vitro macrophage manipulation	6
Evaluating the diversity of circulating natural killer cells between active tuberculosis and latent tuberculosis infection	6
Supplementation of sputum cultures with culture filtrate to detect tuberculosis in a cross-sectional study of HIV-infected individuals	6
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis	6
A population approach of rifampicin pharmacogenetics and pharmacokinetics in Mexican patients with tuberculosis	6
A whole-genome sequencing study of an X-family tuberculosis outbreak focus on transmission chain along 25 years	6
Nontuberculous mycobacteria in the environment	6
Multidrug-resistant patients receiving treatment in Niger who are infected with M. tuberculosis Cameroon family convert faster in smear and culture than those with M. tuberculosis Ghana family	6
Performance of GeneXpert ultra in the diagnosis of Tuberculous Cervical lymphadenitis in formalin fixed paraffin embedded tissues	6
Identification of novel salivary candidate protein biomarkers for tuberculosis diagnosis: A preliminary biomarker discovery study	5
Mycobacterium abscessus drug discovery using machine learning	5
Insights into the molecular pathogenesis of ocular tuberculosis	5
Serological biomarkers for monitoring response to treatment of pulmonary and extrapulmonary tuberculosis in children and adolescents	5
Activating transcription factor 3 protects alveolar epithelial type II cells from Mycobacterium tuberculosis infection-induced inflammation	5
Performance of a simple flow cytometric assay in diagnosing active tuberculosis	5
Mycobacterium bovis BCG moreau is naturally deficient in homologous recombination	5
From the past, a long way to future challenges for a greater control of tuberculosis	5
Potential biomarker enhancing the activity of tuberculosis, hsa-miR-346	5
The diagnostic value of T cell spot test and adenosine deaminase in pleural effusion for tuberculous pleurisy: A systematic review and meta-analysis	5
Preclinical models to optimize treatment of tuberculous meningitis – A systematic review	5
Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics	5
Mab2780c, a TetV-like efflux pump, confers high-level spectinomycin resistance in mycobacterium abscessus	5
Differentially culturable tubercle bacteria dynamics during standard anti-tuberculosis treatment: A prospective cohort study	5
Knockout of MRA_1916 in Mycobacterium tuberculosis H37Ra affects its growth, biofilm formation, survival in macrophages and in mice	5
Transient, inhaled gene therapy with gamma interferon mitigates pathology induced by host response in a mouse model of tuberculosis	5
Pyrazinamide resistance and pncA mutations in drug resistant Mycobacterium tuberculosis clinical isolates from Myanmar	5
Environmental risk of nontuberculous mycobacterial infection: Strategies for advancing methodology	5
Stimulated expression of ELR+ chemokines, VEGFA and TNF-AIP3 promote mycobacterial dissemination in extrapulmonary tuberculosis patients and Cavia porcellus model of tuberculosis	4
Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response	4
MTS1338 in Mycobacterium tuberculosis promotes detoxification of reactive oxygen species under oxidative stress	4
Population structure of multidrug-resistant Mycobacterium tuberculosis clinical isolates in Colombia	4
Evaluation of genotype MTBDRplus V2 and genotype MTBDRsl V2 for the diagnosis of extrapulmonary tuberculosis in India	4
Reinvestigation of the structure-activity relationships of isoniazid	4
Lumbosacral tuberculosis, a rare manifestation of Pott's disease – How identified human skeletons from the pre-antibiotic era can be used as reference cases to establish a palaeopathological diagnosis	4
Significance of the chemokine CXCL10 and human beta-defensin-3 as biomarkers of pulmonary tuberculosis	4
Ubiquitous and multifaceted: SIT53 spoligotype does not correlate with any particular family of Mycobacterium tuberculosis	4
Screening of 20 Mycobacterium tuberculosis sRNAs in plasma for detection of active pulmonary tuberculosis	4
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton	4
LIODetect®TB-ST: Evaluation of novel blood test for a rapid diagnosis of active pulmonary and extra-pulmonary tuberculosis in IGRA confirmed patients	4
Nanotechnology and tuberculosis: An old disease with new treatment strategies	4
Characterization of genetic diversity and clonal complexes by whole genome sequencing of Mycobacterium tuberculosis isolates from Jalisco, Mexico	4
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster	4
Immunogenicity and protection against Mycobacterium avium with a heterologous RNA prime and protein boost vaccine regimen	4
Rv1258c acts as a drug efflux pump and growth controlling factor in Mycobacterium tuberculosis	4
High-throughput screening of compounds library to identify novel inhibitors against latent Mycobacterium tuberculosis using streptomycin-dependent Mycobacterium tuberculosis 18b strain as a model	4
N6-methylated adenine on the target sites of mamA from Mycobacterium bovis BCG enhances macrophage activation by CpG DNA in mice	4
Characterization of probes associated with rifampicin resistance in M.tuberculosis detected by GenXpert from a national reference laboratory at Chennai	4
Preclinical murine models to study lung infection with Mycobacterium abscessus complex	4
Raman spectroscopy and machine learning-based optical probe for tuberculosis diagnosis via sputum	4
Utility of the Whole Genome Sequencing based methodologies in routine European tuberculosis reference laboratory network setting	4
Risk factors associated with large clusters of tuberculosis patients determined by whole-genome sequencing in a high-tuberculosis-burden country	4
Efficacy of inhaled CPZEN-45 in treating tuberculosis in the guinea pig	4
Effects of tafenoquine against active, dormant and resistant Mycobacterium tuberculosis	4
Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket	3
Metagenomic analysis reveals mixed Mycobacterium tuberculosis infection in a 18th century Hungarian midwife	3
Culture independent markers of nontuberculous mycobacterial (NTM) lung infection and disease in the cystic fibrosis airway	3
Genotypic diversity of Mycobacterium tuberculosis isolates and its association with drug-resistance status in Xinjiang, China	3
Utility of cell-free transrenal DNA for the diagnosis of Tuberculous Meningitis: A proof-of-concept study	3
Impact of diabetes mellitus on tuberculosis epidemiology in Indonesia: A mathematical modeling analysis	3
Heterogeneous fitness landscape cues, pknG high expression, and phthiocerol dimycocerosate low production of Mycobacterium tuberculosis ATCC25618 rpoB S450L in enriched broth	3

A high content screening assay for discovery of antimycobacterial compounds based on primary human macrophages infected with virulent Mycobacterium tuberculosis	3
Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections	3
Identification of the inhibitory mechanism of ecumicin and rufomycin 4-7 on the proteolytic activity of Mycobacterium tuberculosis ClpC1/ClpP1/ClpP2 complex	3
Domestic pigs experimentally infected with Mycobacterium bovis and Mycobacterium tuberculosis exhibit different disease outcomes	3
Whole-genome sequencing as a tool for studying the microevolution of drug-resistant serial Mycobacterium tuberculosis isolates	3
Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses	3
The association between vitamin D deficiency and extrapulmonary tuberculosis: Case-control study	3
Telomere length and mitochondrial DNA copy number in multidrug-resistant tuberculosis	3
Evaluation of a new assay for nontuberculous mycobacteria species identification in diagnostic material and cultures	3
Macrophage activation highlight an important role for NER proteins in the survival, latency and multiplication of Mycobacterium tuberculosis	3
Phylogenomic assessment of drug-resistant Mycobacterium tuberculosis strains from Beira, Mozambique	3
Low-cost 3D-printed inverted microscope to detect Mycobacterium tuberculosis in a MODS culture	3
Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3	3
Characteristics of plasma exosomes in drug-resistant tuberculosis patients	3
Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing	3
Tuberculosis vaccination needs to avoid ‘decoy’ immune reactions	3
Treatment of tuberculous meningitis: Overdue for concerted action	3
In vitro activity of tetracycline analogs against multidrug-resistant and extensive drug resistance clinical isolates of Mycobacterium tuberculosis	3
Genetic screening for the protective antigenic targets of BCG vaccination	3
High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course	3
Evolutionary history and spread of the Mycobacterium tuberculosis Latin American and Mediterranean (L4.3/LAM) sublineage, Tunisia	3
Host biomarkers other than interferon gamma in QFT-TB supernatants for identifying active tuberculosis	3
Detecting clusters of high nontuberculous mycobacteria infection risk for persons with cystic fibrosis – An analysis of U.S. counties	3
Elevated antigen-specific IFN-γ responses in bronchoalveolar lavage fluid impervious to clinical comorbidities improve the pulmonary tuberculosis diagnosis	3
Evaluation of a booster tuberculosis vaccine containing mycobacterial DNA-binding protein 1 and CpG oligodeoxynucleotide G9.1 using a Guinea pig model that elicits immunity to Bacillus Calmette–Guérin	3
CD4+ T cell proliferative responses to PPD and CFP-10 associate with recent M. tuberculosis infection	3
Is targeting dysregulation in apoptosis splice variants in Mycobacterium tuberculosis (MTB) host interactions and splicing factors resulting in immune evasion by MTB strategies a possibility?	3
The paleopathology and paleoepidemiology of Upper paleolithic tuberculosis: Review of evidence and hypotheses	2
SLCO1B1 and SLC10A1 polymorphism and plasma rifampin concentrations in patients with co-morbidity tuberculosis-diabetes mellitus in Baja California, Mexico	2
Acquired drug resistance during the turnaround time for drug susceptibility testing impacts outcome of tuberculosis	2
Improving host-directed therapy for tuberculous meningitis by linking clinical and multi-omics data	2
Down-regulation of GAS5 has diagnostic value for tuberculosis and regulates the inflammatory response in mycobacterium tuberculosis infected THP-1 cells	2
Expression of vascular endothelial growth factor (VEGF) and platelet endothelial cell adhesion molecule (PECAM-1/CD31) in intestinal tuberculosis	2
Development of a limited sampling strategy for the estimation of isoniazid exposure considering N-acetyltransferase 2 genotypes in Korean patients with tuberculosis	2
Photoinactivation of non-tuberculous mycobacteria using Zn-phthalocyanine loaded into liposomes	2
Molecular surveillance for large outbreaks of tuberculosis in the United States, 2014–2018	2
Loss of T cells expressing CD27 at the site of active tuberculosis – A prospective diagnostic study	2
Molecular diagnosis of Tuberculous meningitis: sdaA-based multi-targeted LAMP and GeneXpert Ultra	2
Comparison of biochemical parameters and chemokine levels in pleural fluid between patients with anergic and non-anergic tuberculous pleural effusion	2
Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZ	2
Limited sampling strategies for therapeutic drug monitoring of anti-tuberculosis medications: A systematic review of their feasibility and clinical utility	2
Investigating extradomiciliary transmission of tuberculosis: An exploratory approach using social network patterns of TB cases and controls and the genotyping of Mycobacterium tuberculosis	2
Mycobacterium tuberculosis-specific plasmablast levels are differentially modulated in tuberculosis infection and disease	2
Escalate: Linezolid as an add on treatment in the intensive phase of tubercular meningitis. A randomized controlled pilot trial	2
Detection of mycobacteria in paraffin-embedded Ziehl–Neelsen-Stained tissues using digital pathology	2
Identification of immune-related genes and susceptible population of pulmonary tuberculosis by constructing TF-miRNA-mRNA regulatory network	2
Evaluating the effects of Cyclosporine A immunosuppression on Mycobacterial infection by inhaling of Cyclosporine A administrated BALB/c mice with live Bacillus Calmette Guérin	2
Alternative cost-effective media to facilitate MODS culture for diagnostics of tuberculosis	2
Determining the diagnostic potential of Truenat MTB Plus for Tubercular lymphadenitis and detection of drug resistance and a comparison with GeneXpert Ultra	2
Growth-inhibitory effects of tris-(1,10-phenanthroline) iron (II) against Mycobacterium tuberculosis in vitro and in vivo	2
More severe lung lesions in smoker patients with active pulmonary tuberculosis were associated with peripheral NK cell subsets	2
Biomarkers to predict FDG PET/CT activity after the standard duration of treatment for spinal tuberculosis: An exploratory study	2
Immunological characterization of chimeras of high specificity antigens from Mycobacterium tuberculosis H37Rv	2
Biofilms in tuberculosis: What have we learnt in the past decade and what is still unexplored?	2
The role of antibodies in Bacille Calmette Guérin-mediated immune responses and protection against tuberculosis in humans: A systematic review	2
Novel TB smear microscopy automation system in detecting acid-fast bacilli for tuberculosis – A multi-center double blind study	2
The host-pathogen-environment triad: Lessons learned through the study of the multidrug-resistant Mycobacterium tuberculosis M strain	2
Evaluation of CSF pyrosequencing to diagnose tuberculous meningitis: A retrospective diagnostic accuracy study	2
Flow cytometric detection of IFN-γ production and Caspase-3 activation in CD4+ T lymphocytes to discriminate between healthy and Mycobacterium bovis naturally infected water buffaloes	2