OOIR: Observatory of International Research

Papers

(The TQCC of BMC Biotechnology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope	66
Optimization and scale-up of α-amylase production by Aspergillus oryzae using solid-state fermentation of edible oil cakes	59
The osteogenic differentiation of human dental pulp stem cells in alginate-gelatin/Nano-hydroxyapatite microcapsules	50
Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa	41
Development of a method for phycocyanin recovery from filamentous cyanobacteria and evaluation of its stability and antioxidant capacity	34
Efficient CRISPR/Cas9 genome editing with Citrus embryogenic cell cultures	31
Repurposing novel therapeutic candidate drugs for coronavirus disease-19 based on protein-protein interaction network analysis	30
Comparing various protocols of human and bovine ovarian tissue decellularization to prepare extracellular matrix-alginate scaffold for better follicle development in vitro	29
An efficient and specific CRISPR-Cas9 genome editing system targeting soybean phytoene desaturase genes	28
Combined pretreatment of sugarcane bagasse using alkali and ionic liquid to increase hemicellulose content and xylanase production	24
The study of laccase immobilization optimization and stability improvement on CTAB-KOH modified biochar	23
A prospectus of plant growth promoting endophytic bacterium from orchid (Vanda cristata)	22
A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana	22
Lyso-phosphatidylethanolamine primes the plant immune system and promotes basal resistance against hemibiotrophic pathogens	21
Bacillus sp. CSK2 produced thermostable alkaline keratinase using agro-wastes: keratinolytic enzyme characterization	21
CRISPR/Cas9-mediated knockout of clinically relevant alloantigenes in human primary T cells	21
Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics	20
Production of surfactant-stable keratinase from Bacillus cereus YQ15 and its application as detergent additive	19
Levan from Leuconostoc citreum BD1707: production optimization and changes in molecular weight distribution during cultivation	19
Rational design and structure-based engineering of alkaline pectate lyase from Paenibacillus sp. 0602 to improve thermostability	19
Design of a new lyoprotectant increasing freeze-dried Lactobacillus strain survival to long-term storage	19
Heterologous expression of nattokinase from B. subtilis natto using Pichia pastoris GS115 and assessment of its thrombolytic activity	18
Tofu processing wastewater as a low-cost substrate for high activity nattokinase production using Bacillus subtilis	17
Tenebrio molitor: possible source of polystyrene-degrading bacteria	17
Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids	16

Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation	16
An effective combination of codon optimization, gene dosage, and process optimization for high-level production of fibrinolytic enzyme in Komagataella phaffii (Pichia pastoris)	15
Self-limiting fall armyworm: a new approach in development for sustainable crop protection and resistance management	14
Different genome-wide transcriptome responses of Nocardioides simplex VKM Ac-2033D to phytosterol and cortisone 21-acetate	14
Isolation of axenic cyanobacterium and the promoting effect of associated bacterium on axenic cyanobacterium	14
Evaluating the biocontrol potential of Canadian strain Bacillus velezensis 1B-23 via its surfactin production at various pHs and temperatures	14
The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa	14
Genome-scale insights into the metabolic versatility of Limosilactobacillus reuteri	13
Optimization of lipase production using fungal isolates from oily residues	12
Screening of miRNAs in plasma as a diagnostic biomarker for cardiac disease based on optimization of extraction and qRT-PCR condition assay through amplification efficiency	11
One-step fermentation for producing xylo-oligosaccharides from wheat bran by recombinant Escherichia coli containing an alkaline xylanase	11
Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures	11
Target identification of small molecules: an overview of the current applications in drug discovery	11
High level expression and biochemical characterization of an alkaline serine protease from Geobacillus stearothermophilus to prepare antihypertensive whey protein hydrolysate	11
Efficient extraction and antioxidant activity of polyphenols from Antrodia cinnamomea	11
Mining of two novel aldehyde dehydrogenases (DHY-SC-VUT5 and DHY-G-VUT7) from metagenome of hydrocarbon contaminated soils	11
Comparative gene expression profiling of mouse ovaries upon stimulation with natural equine chorionic gonadotropin (N-eCG) and tethered recombinant-eCG (R-eCG)	11
Biochemical characterization of specific Alanine Decarboxylase (AlaDC) and its ancestral enzyme Serine Decarboxylase (SDC) in tea plants (Camellia sinensis)	11
Recombinant laccase rPOXA 1B real-time, accelerated and molecular dynamics stability study	10
Enzymatic degradation is an effective means to reduce aflatoxin contamination in maize	10
Development of a CRISPR/Cpf1 system for targeted gene disruption in Aspergillus aculeatus TBRC 277	10
Antifungal screening of selenium nanoparticles biosynthesized by microcystin-producing Desmonostoc alborizicum	10
Roles of N-linked and O-linked glycosylation sites in the activity of equine chorionic gonadotropin in cells expressing rat luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating	10
Generation of genome-edited dogs by somatic cell nuclear transfer	10
Effectiveness of recombinant Escherichia coli on the production of (R)-(+)-perillyl alcohol	9
Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy	9
Optimization of expression, purification and secretion of functional recombinant human growth hormone in Escherichia coli using modified staphylococcal protein a signal peptide	9
Bacteriostatic effects of benzyl isothiocyanate on Vibrio parahaemolyticus: Transcriptomic analysis and morphological verification	9
Antibacterial, antibiofilm, and anticancer activity of silver-nanoparticles synthesized from the cell-filtrate of Streptomyces enissocaesilis	9
Enhancing docosahexaenoic acid production of Schizochytrium sp. by optimizing fermentation using central composite design	9
Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids	9
Green and environmentally friendly synthesis of silver nanoparticles with antibacterial properties from some medicinal plants	9
Genome-scale model reconstruction of the methylotrophic yeast Ogataea polymorpha	8
Transient light-activated gene expression in Chinese hamster ovary cells	8
Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats	8
Metabolic engineering of energycane to hyperaccumulate lipids in vegetative biomass	8
Production of rhamnolipid biosurfactants in solid-state fermentation: process optimization and characterization studies	8
Development and comparison of cross-linking and non-crosslinking probe-gold nanoparticle hybridization assays for direct detection of unamplified bovine viral diarrhea virus-RNA	8
Designing, optimization, and validation of whole blood direct T-ARMS PCR for precise and rapid genotyping of complex vertebral malformation in cattle	8
Optimizations for identifying reference genes in bone and cartilage bioengineering	8
Failure to maintain full-term pregnancies in pig carrying klotho monoallelic knockout fetuses	8