Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	228
Subscription and Copyright Information	220
Subscription and Copyright Information	198
Advisory Board and Contents	193
Stories in Molecular Medicine December 2021	186
Subscription and Copyright Information	156
Advisory Board and Contents	156
Advisory Board and Contents	149
Subscription and Copyright Information	123
Subscription and Copyright Information	121
m6A and beyond: RNA modifications shaping angiogenesis	118
Fc-optimized checkpoint antibodies for cancer immunotherapy	115
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	110
Pushing the boundaries of brain organoids to study Alzheimer’s disease	109
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	101
Consideration of the importance of measuring thermal discomfort in biomedical research	100
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	100
Neutrophils and extracellular traps in crystal-associated diseases	95
Opportunities and challenges for biomarker discovery using electronic health record data	89
Beneath the radar: immune-evasive cell sources for stroke therapy	88
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	87
d-Amino acids: new clinical pathways for brain diseases	79
Subscription and Copyright Information	76
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	76
Stories in Molecular Medicine November 2021	73

Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	68
Insights from HIV-1 vaccine and passive immunization efficacy trials	67
Brain-specific regulatory T cell expansion limits cognitive decline	67
Engineering cytokines for tumor-targeting and selective T cell activation	66
Acquired resistance to immunotherapy in solid tumors	64
Erythropoietic protoporphyrias: updates and advances	63
Amyloid and collagen templates in aortic valve calcification	63
Molecular mechanisms in the pathogenesis of dengue infections	61
Three ‘E’ challenges for siRNA drug development	60
iPSCs and DRGs: stepping stones to new pain therapies	54
Cell-free circulating tumor DNA profiling in cancer management	53
Microbes and mood: innovative biomarker approaches in depression	53
Advisory Board and Contents	52
Emerging roles of cyclin-dependent kinase 7 in health and diseases	51
RNA immunotherapy: revolutionizing cancer and autoimmune disease treatments	49
Keratinocytes: new perspectives in inflammatory skin diseases	49
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	48
Hormesis as an adaptive response to infection	46
Epigenetic regulation in intervertebral disc degeneration	46
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	45
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	44
Promoting proteostasis by cAMP/PKA and cGMP/PKG	44
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	44
Significant challenges to translating breakthrough science in Mexico	43
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	43
Mitigating age-related somatic mutation burden	43
Shining a light on comorbidities	42
Advisory Board and Contents	42
Advisory Board and Contents	42
Subscription and Copyright Information	41
Subscription and Copyright Information	40
Roadmap for developing biologically inspired therapeutics for genetic brain disorders	40
Pathogenic mechanisms in genetically defined Ehlers–Danlos syndromes	39
SOX17: escape route from immune destruction in early CRC	39
CircRNA perspective: new strategies for RNA therapy	38
The endoplasmic reticulum proteostasis network and bone disease	38
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation	38
Antibody signatures in inflammatory bowel disease: current developments and future applications	37
Translation of gene therapy strategies for amyotrophic lateral sclerosis	36
Subscription and Copyright Information	36
Naked mole-rats: at the heart of it	36
Clinical implications of vitamin B12 as redox-active cofactor	36
Science around the world	36
The emerging Janus face of SVEP1 in development and disease	35
Saving eyesight, one gene at a time	35
The bleeding edge: broadening horizons for hematopoietic stem cell therapies	34
Molecular disease mechanisms of human antineuronal monoclonal autoantibodies	34
Time-restricted feeding and Alzheimer’s disease: you are when you eat	33
Targeting mitochondrial transfer as a promising therapeutic strategy	33
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	32

Maternal obesity: new placental paradigms unfolded	32
Intestinal mucus barrier: a missing piece of the puzzle in food allergy	32
Focused ultrasound gene delivery for the treatment of neurological disorders	31
IL-15 in CAR engineering: striking an efficacy–safety balance	31
Advisory Board and Contents	29
Skin senescence: mechanisms and impact on whole-body aging	29
Incorporating placental pathology into clinical care and research	28
Autoantibodies as drivers of neuropathic pain	28
Advisory Board and Contents	28
Fibroblasts in AKI: small army, big help	28
Science around the world	28
Gasdermins in pyroptosis, inflammation, and cancer	27
ABC transporters: human disease and pharmacotherapeutic potential	27
Advisory Board and Contents	27
Leveraging cellular mechano-responsiveness for cancer therapy	27
Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery	26
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes	26
Cystic fibrosis at a glance: from disease mechanism to therapy	26
The global human gut microbiome: genes, lifestyles, and diet	25
Clock-modulated checkpoints in time-restricted eating	25
Biodiversity: the overlooked source of human health	25
Translational opportunities emerge from genetic influences on health	25
Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach	24
Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes	24
Splicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer	24
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome	24
Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health	24
Subscription and Copyright Information	24
Advisory Board and Contents	23
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	23
Molecular basis and clinical implications of HIFs in cardiovascular diseases	23
Subscription and Copyright Information	23
iPSC-derived models for anorexia nervosa research	23
Advisory Board and Contents	23
Advisory Board and Contents	23
Stratum corneum as polymer sheet: concept and cornification processes	23
Novel universal vaccines to mitigate emerging avian influenza viruses	23
Advisory Board and Contents	22
Circadian molecular clock disruption in chronic pulmonary diseases	22
Subscription and Copyright Information	22
Human dopaminergic system in the exercise-cognition link	22
Dissecting mechanisms of fecal microbiota transplantation efficacy in disease	22
TIM-3 blockade: immune and targeted therapy in DIPG	21
Subscription and Copyright Information	20
Vitiligo: advances in pathophysiology research and treatment development	20
Autoimmune diseases and cardiovascular risk	19
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	19
mRNA vaccine platforms to prevent bacterial infections	19
Understanding the tuberculosis granuloma: the matrix revolutions	19
Vaccine-based immunotherapy and related preclinical models for glioma	19
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	19
AAV capsid design: A Goldilocks challenge	18
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	18
Asthma exacerbations: the Achilles heel of asthma care	18
HPV integration and cervical cancer: a failed evolutionary viral trait	18
Thymic stroma and TFII-I: towards new targeted therapies	18
Staging of Alzheimer’s disease: past, present, and future perspectives	18
Advisory Board and Contents	18
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	18
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	17
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	17
Common mechanisms in pediatric acute liver failure	17
There is nothing as inconsistent as the OSFED diagnostic criteria	17
The dual role of the TSC complex in cancer	16
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	16
Extracellular matrix-based cancer targeting	16
The future of phage therapy in the USA	16
Organ-specific aging in the plasma proteome predicts disease	16
Redefining metalloproteases specificity through network proteolysis	16
Copy number alterations: a catastrophic orchestration of the breast cancer genome	16
Tertiary lymphoid structures in the central nervous system	16
Telomere biology disorders: time for moving towards the clinic?	16
Missing links in preeclampsia cell model systems of endothelial dysfunction	16
IL-6: a pivotal molecule for tumor–brain dysfunction interaction	15
The aging lipidome: exercise is medicine	15
Treatment and research needs for severe eating disorders: a response to Dr Ayton	15
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	15
Secondary failure: immune responses to approved protein therapeutics	15
Dynamic rewiring of neurovasculature in health and disease	15
Advisory Board and Contents	15

Rejuvenating the human gut microbiome	15
Clinical crusade: zosurabalpin's charge against antibiotic resistance	15
Primary cilia shape hallmarks of health and aging	15