Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	261
Subscription and Copyright Information	214
Subscription and Copyright Information	209
Advisory Board and Contents	187
Stories in Molecular Medicine December 2021	178
Advisory Board and Contents	168
m6A and beyond: RNA modifications shaping angiogenesis	163
Subscription and Copyright Information	142
Advisory Board and Contents	123
Subscription and Copyright Information	106
Subscription and Copyright Information	105
Pre-eclampsia: Challenges for Nanomedicine Development in Pregnancy	104
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	101
Fc-optimized checkpoint antibodies for cancer immunotherapy	99
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	94
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	90
Neutrophils and extracellular traps in crystal-associated diseases	87
Consideration of the importance of measuring thermal discomfort in biomedical research	81
Pushing the boundaries of brain organoids to study Alzheimer’s disease	78
Printing New Bones: From Print-and-Implant Devices to Bioprinted Bone Organ Precursors	76
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	76
Opportunities and challenges for biomarker discovery using electronic health record data	75
Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines	74
d-Amino acids: new clinical pathways for brain diseases	72
Beneath the radar: immune-evasive cell sources for stroke therapy	68

Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	67
Subscription and Copyright Information	65
Brain-specific regulatory T cell expansion limits cognitive decline	64
Stories in Molecular Medicine November 2021	64
Erythropoietic protoporphyrias: updates and advances	63
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	62
iPSCs and DRGs: stepping stones to new pain therapies	61
In Utero Gene Therapy: Progress and Challenges	59
Molecular mechanisms in the pathogenesis of dengue infections	55
Engineering cytokines for tumor-targeting and selective T cell activation	54
Insights from HIV-1 vaccine and passive immunization efficacy trials	53
Amyloid and collagen templates in aortic valve calcification	53
Keratinocytes: new perspectives in inflammatory skin diseases	52
Acquired resistance to immunotherapy in solid tumors	52
Cell-free circulating tumor DNA profiling in cancer management	49
Emerging roles of cyclin-dependent kinase 7 in health and diseases	47
Microbes and mood: innovative biomarker approaches in depression	46
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	45
Advisory Board and Contents	45
Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation	44
Hormesis as an adaptive response to infection	44
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	42
Epigenetic regulation in intervertebral disc degeneration	42
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	42
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	40
Three ‘E’ challenges for siRNA drug development	40
Clinical implications of vitamin B12 as redox-active cofactor	39
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	39
Antibody signatures in inflammatory bowel disease: current developments and future applications	39
Promoting proteostasis by cAMP/PKA and cGMP/PKG	39
Mitigating age-related somatic mutation burden	38
Advisory Board and Contents	37
Advisory Board and Contents	37
CircRNA perspective: new strategies for RNA therapy	37
Pathogenic mechanisms in genetically defined Ehlers–Danlos syndromes	36
SOX17: escape route from immune destruction in early CRC	36
Subscription and Copyright Information	36
Shining a light on comorbidities	36
Significant challenges to translating breakthrough science in Mexico	35
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation	35
Subscription and Copyright Information	35
Roadmap for developing biologically inspired therapeutics for genetic brain disorders	35
Subscription and Copyright Information	34
Naked mole-rats: at the heart of it	34
Science around the world	34
Saving eyesight, one gene at a time	33
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	33
The emerging Janus face of SVEP1 in development and disease	32
Translation of gene therapy strategies for amyotrophic lateral sclerosis	32
Time-restricted feeding and Alzheimer’s disease: you are when you eat	31

Treatment and Prevention of Neurocristopathies	30
The bleeding edge: broadening horizons for hematopoietic stem cell therapies	30
Molecular disease mechanisms of human antineuronal monoclonal autoantibodies	29
Maternal obesity: new placental paradigms unfolded	29
Translational opportunities emerge from genetic influences on health	28
Focused ultrasound gene delivery for the treatment of neurological disorders	28
Skin senescence: mechanisms and impact on whole-body aging	28
Intestinal mucus barrier: a missing piece of the puzzle in food allergy	28
Science around the world	27
Predicting Bone Regeneration with a Simple Blood Test	27
Splicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer	27
Advisory Board and Contents	27
Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach	26
Leveraging cellular mechano-responsiveness for cancer therapy	26
Clock-modulated checkpoints in time-restricted eating	26
Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health	26
Advisory Board and Contents	26
Cystic fibrosis at a glance: from disease mechanism to therapy	25
Advisory Board and Contents	24
Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes	24
Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery	24
Ex Vivo Complement Activation on Endothelial Cells: Research and Translational Value	24
Incorporating placental pathology into clinical care and research	24
ABC transporters: human disease and pharmacotherapeutic potential	24
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes	24
Gasdermins in pyroptosis, inflammation, and cancer	24
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome	23
Biodiversity: the overlooked source of human health	23
iPSC-derived models for anorexia nervosa research	23
The global human gut microbiome: genes, lifestyles, and diet	23
Subscription and Copyright Information	22
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	22
Molecular basis and clinical implications of HIFs in cardiovascular diseases	22
Advisory Board and Contents	22
Historical Perspective of Clinical Nano and Microparticle Formulations for Delivery of Therapeutics	22
Novel universal vaccines to mitigate emerging avian influenza viruses	22
Subscription and Copyright Information	22
Advisory Board and Contents	22
Human dopaminergic system in the exercise-cognition link	22
Circadian molecular clock disruption in chronic pulmonary diseases	21
Molecular Mechanisms and Treatment Options of Nephropathic Cystinosis	21
Tooth Repair and Regeneration: Potential of Dental Stem Cells	21
Stratum corneum as polymer sheet: concept and cornification processes	21
Cancer Surgery 2.0: Guidance by Real-Time Molecular Technologies	21
Subscription and Copyright Information	20
Dissecting mechanisms of fecal microbiota transplantation efficacy in disease	20
Advisory Board and Contents	20
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	20
TIM-3 blockade: immune and targeted therapy in DIPG	20
AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies	20
Vaccine-based immunotherapy and related preclinical models for glioma	19
Subscription and Copyright Information	18
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	18
Vitiligo: advances in pathophysiology research and treatment development	18
Asthma exacerbations: the Achilles heel of asthma care	18
HPV integration and cervical cancer: a failed evolutionary viral trait	18
Understanding the tuberculosis granuloma: the matrix revolutions	18
Autoimmune diseases and cardiovascular risk	18
Staging of Alzheimer’s disease: past, present, and future perspectives	18
mRNA vaccine platforms to prevent bacterial infections	17
Advisory Board and Contents	17
Common mechanisms in pediatric acute liver failure	17
AAV capsid design: A Goldilocks challenge	17
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	17
Tertiary lymphoid structures in the central nervous system	17
There is nothing as inconsistent as the OSFED diagnostic criteria	17
Strategies to Identify Genetic Variants Causing Infertility	17
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	16
The dual role of the TSC complex in cancer	16
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	16
Organ-specific aging in the plasma proteome predicts disease	16
Telomere biology disorders: time for moving towards the clinic?	16
Redefining metalloproteases specificity through network proteolysis	16
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	15
Extracellular matrix-based cancer targeting	15
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	15
Thymic stroma and TFII-I: towards new targeted therapies	15
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	15
Clinical crusade: zosurabalpin's charge against antibiotic resistance	14
Treatment and research needs for severe eating disorders: a response to Dr Ayton	14

Missing links in preeclampsia cell model systems of endothelial dysfunction	14
Stories in Molecular Medicine June 2021	14
The aging lipidome: exercise is medicine	14
The future of phage therapy in the USA	14
Copy number alterations: a catastrophic orchestration of the breast cancer genome	14
Rejuvenating the human gut microbiome	14
Advisory Board and Contents	14
Primary cilia shape hallmarks of health and aging	14
Advisory Board and Contents	14
Nanocarrier vaccines for respiratory infections	13
Adenoviruses in medicine: innocuous pathogen, predator, or partner	13
Enhancers in disease: molecular basis and emerging treatment strategies	13
Cancer driver mutations: predictions and reality	13
Safety of non-replicative and oncolytic replication-selective HSV vectors	13
Secondary failure: immune responses to approved protein therapeutics	13
Dynamic rewiring of neurovasculature in health and disease	13
Multiomics tools for improved atherosclerotic cardiovascular disease management	13
Helicobacter pylori-induced NF-κB: trailblazer for gastric pathophysiology	13
Are GLP-1R agonists the long-sought-after panacea for obesity?	12
Short-chain fatty acids in fetal development and metabolism	12
Advisory Board and Contents	12
Bearing allostatic load: insights into a more equitable future within cardio-oncology	12
Advances in Hodgkin lymphoma research	12
Advisory Board and Contents	12
Correction to: Mitochondria as Therapeutic Targets in Transplantation	12
Digital health applications for eating disorders treatment	12
Subscription and Copyright Information	12
Stories in Molecular Medicine July 2021	11
Science around the world	11
Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements	11
Advisory Board and Contents	11
Subscription and Copyright Information	11
Pig models for translational Duchenne muscular dystrophy research	11
Subscription and Copyright Information	11
Nontraditional models as research tools: the road not taken	11
Interdisciplinary approaches for the discovery of novel antifungals	11
Toward low-cost gene therapy: mRNA-based therapeutics for treatment of inherited retinal diseases	10
Gene therapy for β-thalassemia: current and future options	10
Brain-related sexual dimorphism in tuberous sclerosis complex: an overlooked matter	10
Nanobodies as a powerful platform for biomedicine	10
Updates and advances in pyruvate kinase deficiency	10
Epigenetic regulation of tumor-immune symbiosis in glioma	10
Novel bladder-sparing approaches in patients with muscle-invasive bladder cancer	10
Clonal hematopoiesis of indeterminate potential: the root cause of, and fertile ground for, hematological malignancies	9
Physical activity, cathepsin B, and cognitive health	9
Preimplantation Genetic Testing for Aneuploidy – a Castle Built on Sand	9
Circadian Angiopoietin-Like-4 as a Novel Therapy in Cardiovascular Disease	9
Advisory Board and Contents	9
Advisory Board and Contents	9
Antibody class-switching as a strategy to improve HIV-1 neutralization	9
The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis	9
Subscription and Copyright Information	9
Exposing the role of metals in neurological disorders: a focus on manganese	8
Correction to: siRNA modification and delivery for drug development	8
Cell-free and extrachromosomal DNA profiling of small cell lung cancer	8
Erythrophagocytes in hemolytic anemia, wound healing, and cancer	8
Nutrition interventions in congenital disorders of glycosylation	8
PIK3CA-related overgrowth: silver bullets from the cancer arsenal?	8
The body is not just impacted by eating disorders – biology drives them	8
Subscription and Copyright Information	8
Genetic causes of obesity: mapping a path forward	8
Can’t handle the stress? Mechanobiology and disease	8
Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time?	8
Exploiting pancreatic cancer metabolism: challenges and opportunities	8
Recent insights into lysosomal acid lipase deficiency	8
Patients as biomedical researchers	8
Development of asparagine endopeptidase inhibitors for treating neurodegenerative diseases	8
NK cells in the brain: implications for brain tumor development and therapy	8
Advancements and challenges in mouse models of Alzheimer’s disease	8
Subscription and Copyright Information	7
Post-acute anti-NMDAR encephalitis mirrors schizophrenia	7
RyR-mediated calcium release in hippocampal health and disease	7
Polycystic kidney disease: novel insights into polycystin function	7
Microbiome-targeted interventions for the control of oral–gut dysbiosis and chronic systemic inflammation	7
Suicide prevention in cancer: earlier is better	7
Advisory Board and Contents	7
SARS-CoV-2 targets the liver and manipulates glucose metabolism	7
Pulmonary fibrosis: from pathogenesis to clinical decision-making	7
Advisory Board and Contents	7
Molecular therapy for polyQ disorders: from bench to clinical trials	7
Circular RNA translation: novel protein isoforms and clinical significance	7
Translating osteoarthritis genetics research: challenging times ahead	7
Stories in Molecular Medicine September 2021	7
Advisory Board and Contents	7
Science around the world	7
Pulmonary arterial hypertension and cancer: exploring their resemblance as channelopathies	7
A sex-biased target against demyelination in Alzheimer’s disease	7
Convalescent plasma to deliver therapeutic antibodies against COVID-19	7
Subscription and Copyright Information	7
Fatty acid binding proteins in multiple myeloma	6
Subscr+copyr	6
Genetically modified malaria parasites as vaccine candidates	6
Molecular links between allergy and cancer	6
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?	6
How aging impacts vaccine efficacy: known molecular and cellular mechanisms and future directions	6