Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	355
Advisory Board and Contents	221
Subscription and Copyright Information	185
Advisory Board and Contents	180
Endocrinology-informed neuroimaging in eating disorders: GLP1, orexins, and psilocybin	159
PD-L1 at the crossroad between RNA metabolism and immunosuppression	134
CXCR2 chemokine receptor – a master regulator in cancer and physiology	133
Towards Advanced iPSC-based Drug Development for Neurodegenerative Disease	128
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	107
Targeting PERK to treat arrhythmias	100
A cryptic mode of GPCR regulation revealed	91
Advisory Board and Contents	87
Control of DUX4 Expression in Facioscapulohumeral Muscular Dystrophy and Cancer	85
Subscr+copyr	79
SARS-CoV-2 targets the liver and manipulates glucose metabolism	77
Subscription and Copyright Information	76
Advisory Board and Contents	74
Advisory Board and Contents	67
Advisory Board and Contents	66
Advisory Board and Contents	65
Stories in Molecular Medicine April 2021	65
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Stories in Molecular Medicine December 2021	62
Stories in Molecular Medicine: March 2021	57
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Stories in Molecular Medicine September 2021	55
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Resistance exercise for anxiety and depression: efficacy and plausible mechanisms	53
Bridging rapid and sustained antidepressant effects of ketamine	52
Autoimmune diseases and cardiovascular risk	50
Neutrophils and extracellular traps in crystal-associated diseases	48
TIM-3 blockade: immune and targeted therapy in DIPG	47
Advisory Board and Contents	46
Subscription and Copyright Information	46
Targeting low-risk myelodysplastic syndrome with novel therapeutic strategies	45
Consideration of the importance of measuring thermal discomfort in biomedical research	44
Advisory Board and Contents	44
Advisory Board and Contents	42
Polycystic kidney disease: novel insights into polycystin function	41
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Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	39
Cutaneous neuroimmune crosstalk in pruritus	39
Convalescent plasma to deliver therapeutic antibodies against COVID-19	39
Homeostatic maintenance of the lymphatic vasculature	38
Bringing vascularization into glioblastoma in vitro models	38
Asthma exacerbations: the Achilles heel of asthma care	35
Advisory Board and Contents	35
Pre-eclampsia: Challenges for Nanomedicine Development in Pregnancy	34
Unleashing cell-penetrating peptide applications for immunotherapy	34
Meeting the needs of patients with ultrarare diseases	34
Beneath the radar: immune-evasive cell sources for stroke therapy	34
AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies	34
Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease	34
Post-acute anti-NMDAR encephalitis mirrors schizophrenia	33
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	33
Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges	33
The gut microbiome as a biomarker of differential susceptibility to SARS-CoV-2	33
TIM-3 inhibitors: a promising strategy for tumor immunotherapy	33
Challenges and opportunities for conceiving genetically diverse sickle cell mice	32
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	32
Subscription and Copyright Information	31
Targeting CDK2 to circumvent treatment resistance in HR+ breast cancer	31
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	31
Translating osteoarthritis genetics research: challenging times ahead	30
Microbiome-targeted interventions for the control of oral–gut dysbiosis and chronic systemic inflammation	30
mRNA vaccine platforms to prevent bacterial infections	30
Advisory Board and Contents	28
Opportunities and challenges for biomarker discovery using electronic health record data	28
Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines	28
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	28
Beyond the danger signal: RNA aggregates orchestrate immunotherapy	28
Influenza A Viruses: Understanding Human Host Determinants	27
RyR-mediated calcium release in hippocampal health and disease	27
Science around the world	27

Advisory Board and Contents	27
Subscription and Copyright Information	26
Fc-optimized checkpoint antibodies for cancer immunotherapy	25
Alternative splicing: a bridge connecting NAFLD and HCC	25
Dietary interventions and precision nutrition in cancer therapy	25
Vascular dysfunction in Hutchinson–Gilford progeria syndrome	24
Microbiota and sleep: awakening the gut feeling	24
Staging of Alzheimer’s disease: past, present, and future perspectives	24
Unmasking BACE1 in aging and age-related diseases	24
PROT3EcT, engineered Escherichia coli for the targeted delivery of therapeutics	24
Understanding the tuberculosis granuloma: the matrix revolutions	24
Imaging genomics: data fusion in uncovering disease heritability	23
Vitiligo: advances in pathophysiology research and treatment development	23
HPV integration and cervical cancer: a failed evolutionary viral trait	23
Molecular therapy for polyQ disorders: from bench to clinical trials	22
Neuroendocrine insights into neurosteroid therapy for postpartum depression	22
Organoids, Where We Stand and Where We Go	22
Printing New Bones: From Print-and-Implant Devices to Bioprinted Bone Organ Precursors	22
COVID-19 in pregnancy: implications for fetal brain development	22
The physiology of bilirubin: health and disease equilibrium	21
AAV capsid design: A Goldilocks challenge	21
Circular RNA translation: novel protein isoforms and clinical significance	21
Hidden mysteries behind genome, epigenome, and exposome of lupus erythematosus	21
Pushing the boundaries of brain organoids to study Alzheimer’s disease	21
Suicide prevention in cancer: earlier is better	21
Breakthroughs and bottlenecks in autophagy research	21
Particulate matter and Alzheimer’s disease: an intimate connection	21
The variant landscape and function of DDX3X in cancer and neurodevelopmental disorders	20
d-Amino acids: new clinical pathways for brain diseases	20
Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies	19
Advisory Board and Contents	18
Harnessing the healing power of love	18
Organ-specific aging in the plasma proteome predicts disease	18
m6A and beyond: RNA modifications shaping angiogenesis	18
Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation	18
Subscription and Copyright Information	18
Vaccine-based immunotherapy and related preclinical models for glioma	18
Insights from HIV-1 vaccine and passive immunization efficacy trials	18
Science around the world	18
Fibrodysplasia ossificans progressiva emerges from obscurity	17
New strategies for the treatment of chronic hepatitis B	17
Oligodendrocyte pathology in Huntington’s disease: from mechanisms to therapeutics	17
Targeting ACC for NASH resolution	17
IBD disease-modifying therapies: insights from emerging therapeutics	17
Common mechanisms in pediatric acute liver failure	17
Three ‘E’ challenges for siRNA drug development	16
Advisory Board and Contents	16
Readthrough compounds for nonsense mutations: bridging the translational gap	16
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Science around the world	16
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Turning the tide in aggressive lymphoma: liquid biopsy for risk-adapted treatment strategies	16
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Communicating science and protecting scientists in a time of political instability	16
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	15
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	15
Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation	15
Senescence and tissue fibrosis: opportunities for therapeutic targeting	15
Improving participant representation in the era of digital clinical studies	15
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Redefining metalloproteases specificity through network proteolysis	14
Missing links in preeclampsia cell model systems of endothelial dysfunction	14
Ectodysplasin A2 receptor signaling in skeletal muscle pathophysiology	14
Advisory Board and Contents	14
Host-informed therapies for the treatment of pneumococcal pneumonia	14
Can we provide quality #MedEd on social media?	14
In Utero Gene Therapy: Progress and Challenges	14
How hypocretin agonists may improve the quality of wake in narcolepsy	13
The Need for Research-Grade Systems Modeling Technologies for Life Science Education	13
Advisory Board and Contents	13
Stories in Molecular Medicine November 2021	13
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	13
Molecular links between allergy and cancer	13
Epigenetic priming in neurodevelopmental disorders	13
Stories in Molecular Medicine October 2021	13
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects	12
β2ARs: double edge sword in heart function	12
Brain-specific regulatory T cell expansion limits cognitive decline	12
A Rare Kidney Disease To Cure Them All? Towards Mechanism-Based Therapies for Proteinopathies	12

Copy number alterations: a catastrophic orchestration of the breast cancer genome	11
Circadian phase instability in bipolar disorder: a neglected essence	11
Deep learning for subtyping the Alzheimer’s disease spectrum	11
Beyond memory impairment: the complex phenotypic landscape of Alzheimer’s disease	11
Mitochondria as Therapeutic Targets in Transplantation	11
Molecular mechanisms in the pathogenesis of dengue infections	11
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	11
Microbes and mood: innovative biomarker approaches in depression	11
Leveraging insights from cancer to improve tuberculosis therapy	11
Emerging roles of cyclin-dependent kinase 7 in health and diseases	10
Monoamines' role in islet cell function and type 2 diabetes risk	10
Strategies to Identify Genetic Variants Causing Infertility	10
Molecular pathology of rare progeroid diseases	10
Unlocking the potential of agonist antibodies for treating cancer using antibody engineering	10
Thymic stroma and TFII-I: towards new targeted therapies	10
Post-Transcriptional Regulation in Skeletal Muscle Development, Repair, and Disease	10
Hormesis as an adaptive response to infection	10
Targeting monoamine oxidases in cancer: advances and opportunities	10
Cancer quiescence: non-coding RNAs in the spotlight	10
If it ain’t broke, break it: facilitating antigen cross-presentation	10
Advisory Board and Contents	10
Engineering Strategies for Allogeneic Solid Tissue Acceptance	10
Telomere biology disorders: time for moving towards the clinic?	10
Advisory Board and Contents	9
The dual role of the TSC complex in cancer	9
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	9
Cell-free circulating tumor DNA profiling in cancer management	9
iPSCs and DRGs: stepping stones to new pain therapies	9
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?	9
Amyloid and collagen templates in aortic valve calcification	9
Anorexia nervosa: diagnostic, therapeutic, and risk biomarkers in clinical practice	9
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	9
Breakthroughs and Bottlenecks in Microbiome Research	9
Epigenetic regulation in intervertebral disc degeneration	9
The inaccessible road to science for people with disabilities	9
There is nothing as inconsistent as the OSFED diagnostic criteria	9
COVID-19 vaccines in pregnancy	8
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	8
The gut vascular barrier: a new player in the gut–liver–brain axis	8
Extracellular matrix-based cancer targeting	8
Role and therapeutic implications of protein glycosylation in neuroinflammation	8
Tertiary lymphoid structures in the central nervous system	8
Erythropoietic protoporphyrias: updates and advances	8
The molecular underpinnings of female predominance in lupus	8
Data-Driven Modeling of Pregnancy-Related Complications	8
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	7
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	7
N6-methyladenosine-mediated gene regulation and therapeutic implications	7
Primary cilia shape hallmarks of health and aging	7
Moyamoya disease emerging as an immune-related angiopathy	7
Eating disorders and obesity: bridging clinical, neurobiological, and therapeutic perspectives	7
The NRF2/Keap1 pathway as a therapeutic target in inflammatory bowel disease	7
FSP1: a key regulator of ferroptosis	7
Genetically modified malaria parasites as vaccine candidates	6
Advisory Board and Contents	6
Subscription and Copyright Information	6
Deciphering the Identity of Renin Cells in Health and Disease	6
Tackling ‘lost in translation’ issues: a response to Perez-Campos et al.	6
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	6
Advisory Board and Contents	6
The spike hypothesis in vaccine-induced adverse effects: questions and answers	6
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Advisory Board and Contents	6
Biomarker opportunities in the treatment of cancer-related depression	6
CircRNA perspective: new strategies for RNA therapy	6
Advisory Board and Contents	6
Shining a light on comorbidities	6
Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy	6
Advisory Board and Contents	6
Advisory Board and Contents	6
Secondary failure: immune responses to approved protein therapeutics	6
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	6
Amphiphysin-2 (BIN1) functions and defects in cardiac and skeletal muscle	6
Dysregulation of deubiquitinylases: a linchpin of gastrointestinal diseases	6
The science of storytelling: the David Attenborough style of scientific presentation	5
Beyond pluripotency: Yamanaka factors drive brain growth and regeneration	5
Bringing gene therapy to where it’s needed	5
Environmental perception and control of gastrointestinal immunity by the enteric nervous system	5
Fruitful Futures for Reproductive Health	5
Advisory Board and Contents	5
Unveiling the biological functions and therapeutic potentials of LONP1 in the ovary	5
SOX17: escape route from immune destruction in early CRC	5
Follow the CSF flow: probing multiciliated ependymal cells in brain pathology	5
Fatty acid binding proteins in multiple myeloma	5
Galectin-3 in metabolic disorders: mechanisms and therapeutic potential	5
3-O-acylated bile acids: disrupters or harmonizers of metabolism?	5
HDL and SARS CoV-2: emerging theragnostic implications	5
From disparities to equity: striving for more in our treatments for feeding and eating disorders	4
Enhancers in disease: molecular basis and emerging treatment strategies	4
Advisory Board and Contents	4
The current sociocultural background of eating disorders	4
Emerging roles of MRG15 in liver metabolic diseases	4
PARsylation-mediated ubiquitylation: lessons from rare hereditary disease Cherubism	4
New media facilitate adolescents’ body dissatisfaction and eating disorders in Mainland China	4
TBCK syndrome: a rare multi-organ neurodegenerative disease	4