OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Immunology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Advisory Board and Contents	439
Advisory Board and Contents	364
Advisory Board and Contents	352
Subscription and Copyright Information	187
DNA flexibility can shape the preferential hypermutation of antibody genes	168
Type 2 conventional dendritic cell functional heterogeneity: ontogenically committed or environmentally plastic?	149
Dietary fibers affecting gastrointestinal immunity	146
Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2	136
On tending sprouts: empowering emerging immunologists in Latin America	120
Lymph node stromal cells: subsets and functions in health and disease	116
Ragulator-Rag and ROS TORment gasdermin D pore formation	115
Novel insights and recent progress in osteoimmunology	110
Innate immunity: the bacterial connection	93
Contribution of gut-derived T cells to extraintestinal autoimmune diseases	87
Tensor-based insights into systems immunity and infectious disease	83
Metabolic and stress response adaptations in T cells to fever and physiological heat	75
Emerging roles of Dectin-1 in noninfectious settings and in the CNS	73
Subscription and Copyright Information	70
Loss of ARID1A ‘loops’ in STING	66
EmBmem: will the real memory B cell please stand up?	66
Trained immunity-based mucosal immunotherapies for the prevention of respiratory infections	65
BCR signaling in germinal center B cell selection	65
DNA at the center of mammalian innate immune recognition of bacterial biofilms	64
Risk factors of cytokine release syndrome: stress, catecholamines, and beyond	63
Generalized pustular psoriasis: immunological mechanisms, genetics, and emerging therapeutics	60

Inflammatory and immune etiology of type 2 diabetes	59
Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy?	57
Targeting WSTF degradation to resolve chronic inflammation	55
Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine	53
Homeostatic chemokines as putative therapeutic targets in idiopathic pulmonary fibrosis	53
The tumor niche can reprogram long-lived protumorigenic neutrophils	53
Oxidative battles in tuberculosis: walking the ferroptotic tightrope	52
Agents of cancer immunosurveillance: HSPs and dsDNA	52
Context-dependent regulation of follicular helper T cell survival	50
The five senses of immunity	50
Infusion of neutralization into Lassa vaccine design	48
Subscription and Copyright Information	47
Leveraging community engagement to shape biomedical research priorities	45
Tumor microenvironment metabolites directing T cell differentiation and function	45
Cytosolic delivery of innate immune agonists	45
Targeting Th17 cells in HIV-1 remission/cure interventions	44
The translational potential of studying bat immunity	44
Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology	43
High endothelial venules as potential gateways for therapeutics	43
Microglia as integrators of brain-associated molecular patterns	43
Maternal inflammation and its ramifications on fetal neurodevelopment	42
Unanticipated specificity in effector-triggered immunity	42
Genotype–phenotype landscapes for immune–pathogen coevolution	41
Advisory Board and Contents	40
Subscription and Copyright Information	40
Subscription and Copyright Information	40
Subscription and Copyright Information	40
Subscription and Copyright Information	40
Chopped! Newfound GSDMD cleavage facilitates tolerance to food allergens	39
Natural resistance against infections: focus on COVID-19	38
Astrocytes ACLYmate to chronic neuroinflammation	38
B cells masquerade as dendritic cells	37
Bridging anatomical gaps between brain and immune system	36
Original antigenic sin: not so sinful after all	35
Intracellular C1q – an unexpected player in neuronal proteostasis	34
Antigen presentation by MHC-E: a putative target for vaccination?	33
Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments	33
Monoallelic expression in human immune cells: linking genotype to phenotype	32
Subscription and Copyright Information	32
The complex immunological role of Helicobacter in modulating cancer	31
TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus	30
Lymphoid tissue on the mind	30
Emerging roles for tRNAs in hematopoiesis and hematological malignancies	30
Calreticulin surface presentation can promote quality control of hematopoietic stem cells	30
Spiking SARS-CoV-2 antiviral immunity in the respiratory tract	30
Old macrophages lose their (circadian) rhythm	30
Transcription factor-driven regulation of ILC1 and ILC3	29
LNCing RNA to immunity	29
Advisory Board and Contents	29
Advisory Board and Contents	28

Advisory Board and Contents	28
Gut microbiota–host post-translational modification axis in immunometabolic diseases	27
Protists protecting food tolerance	27
Signaling is the pathway to macrophage function	27
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers	27
Putative role of STING-mitochondria associated membrane crosstalk in immunity	26
Using structure-function information from IFN-γ-binding proteins and biased agonists to uncouple immunostimulatory and immunosuppressive activities	26
Exploring mucosal immune development and function in utero	26
Subscription and Copyright Information	25
Advisory Board and Contents	25
Harder, better, faster, stronger: biochemistry and biophysics in the immunosurveillance concert	25
Chimeric antigen receptor Treg therapy in transplantation	25
Immunotherapy response-associated Akkermansia: canary in a coal mine?	25
New insights into innate immunity in Alzheimer’s disease: from APOE protective variants to therapies	25
Advisory Board and Contents	25
Overcoming gender bias in STEM	25
Targeting the metabolism of tumor-infiltrating regulatory T cells	25
Protect, repair, rewire, and defend	24
The predictive power of systems immunology	24
Immune-featured decidual stromal cells: pregnancy's multitasking superstars	24
Sensory nerves unlock the TOLL-7 gate for cancer spread	23
Th17 cells: from gut homeostasis to CNS pathogenesis	23
Multiple sclerosis: role of meningeal lymphoid aggregates in progression independent of relapse activity	23
Subscription and Copyright Information	23
BCG vaccination induces cross-protective immunity against pathogenic microorganisms	23
TCR-sequencing in cancer and autoimmunity: barcodes and beyond	23
Sensory neuronal control of skin barrier immunity	22
Life and death of tolerogenic dendritic cells	22
Subscription and Copyright Information	22
CD8+ Tregs kill pathogenic cells to avert autoimmunity	22
Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy	22
Regulation and impact of tumor-specific CD4+ T cells in cancer and immunotherapy	22
Partners and guardians of the nervous and immune systems	21
COVID-19 thromboinflammation: adding inflammatory fibrin to the puzzle	21
Feeding the wrath with myelin	21
The diversity of cGLR receptors: shedding new light on innate immunity	20
Development of a circadian immune system	20
B cell phylogenetics in the single cell era	20
The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases	20
SARS-CoV-2 evolution from the BA.2.86 to JN.1 variants: unexpected consequences	19
Repurposing of old drugs for unleashing innate immunity	19
Finding your niche: immune evasion in quiescent tumor reservoirs	18
Inflammasome diversity: exploring novel frontiers in the innate immune response	18
RORγt protein modifications and IL-17-mediated inflammation	18
How do autoimmune CD4+ T cells handle exhaustion?	18
Lymph node fibroblast-produced extracellular matrix shapes immune function	18
Why are there so few (or so many) circulating coronaviruses?	17
Melanoma-derived mediators can foster the premetastatic niche: crossroad to lymphatic metastasis	17
cGAS-like receptors: back to the future	17
The extracellular matrix and immunity: breaking the old barrier in cancer	17
Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment	17
Human neutrophil kinetics: a call to revisit old evidence	17
News from the T cell trogocytosis front	17
Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity	16
Early clues regarding the pathogenesis of long-COVID	16
Advisory Board and Contents	15
ICOS-play: dressing T cells for residency	15
RNA circuits and RNA-binding proteins in T cells	15
Lipid regulation of NLRP3 inflammasome activity through organelle stress	14
Exhausted CD8+ T cells face a developmental fork in the road	14
Molecular mimicry as a driver of T cell-mediated tumour immunity	14
Turning cold tumors hot: from molecular mechanisms to clinical applications	14
Physiological role of cytokines in the regulation of mammalian metabolism	14
Inflammasomopathies: mechanisms and disease signatures	14
Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice	14
Macrophage states: there's a method in the madness	14
Advisory Board and Contents	14
Breaking down IgA: Tomasiella immunophila enlightens microbiome–immune interactions	14
Restriction factors regulating human herpesvirus infections	14
Neuro–immune crosstalk: focus on innate lymphoid cells	14
Unraveling B cell trajectories at single cell resolution	14