OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Immunology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Subscription and Copyright Information	492
Advisory Board and Contents	406
On tending sprouts: empowering emerging immunologists in Latin America	402
‘Smelling’ lipid cues: chemosensory receptors tune tumor-associated macrophage behavior	222
Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2	198
Advisory Board and Contents	167
Dietary fibers affecting gastrointestinal immunity	158
Advisory Board and Contents	157
Subscription and Copyright Information	150
Contribution of gut-derived T cells to extraintestinal autoimmune diseases	126
Novel insights and recent progress in osteoimmunology	122
Tensor-based insights into systems immunity and infectious disease	97
DNA flexibility can shape the preferential hypermutation of antibody genes	94
Type 2 conventional dendritic cell functional heterogeneity: ontogenically committed or environmentally plastic?	90
Metabolic and stress response adaptations in T cells to fever and physiological heat	89
Innate immunity: the bacterial connection	80
Loss of ARID1A ‘loops’ in STING	75
Risk factors of cytokine release syndrome: stress, catecholamines, and beyond	71
DNA at the center of mammalian innate immune recognition of bacterial biofilms	68
EmBmem: will the real memory B cell please stand up?	67
Subscription and Copyright Information	67
The tumor niche can reprogram long-lived protumorigenic neutrophils	64
Targeting WSTF degradation to resolve chronic inflammation	63
Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy?	61
Trained immunity-based mucosal immunotherapies for the prevention of respiratory infections	60

Beyond the innate immune system: rethinking inflammasomes in multiple sclerosis	59
Inflammatory and immune etiology of type 2 diabetes	59
Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine	57
Homeostatic chemokines as putative therapeutic targets in idiopathic pulmonary fibrosis	51
Oxidative battles in tuberculosis: walking the ferroptotic tightrope	51
BCR signaling in germinal center B cell selection	50
Generalized pustular psoriasis: immunological mechanisms, genetics, and emerging therapeutics	49
Advisory Board and Contents	49
Infusion of neutralization into Lassa vaccine design	48
Unanticipated specificity in effector-triggered immunity	47
Leveraging community engagement to shape biomedical research priorities	47
Genotype–phenotype landscapes for immune–pathogen coevolution	46
Subscription and Copyright Information	46
Context-dependent regulation of follicular helper T cell survival	45
Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology	44
The translational potential of studying bat immunity	44
The five senses of immunity	44
Cytosolic delivery of innate immune agonists	43
Maternal inflammation and its ramifications on fetal neurodevelopment	42
Agents of cancer immunosurveillance: HSPs and dsDNA	41
High endothelial venules as potential gateways for therapeutics	41
Targeting Th17 cells in HIV-1 remission/cure interventions	40
Tumor microenvironment metabolites directing T cell differentiation and function	40
Microglia as integrators of brain-associated molecular patterns	38
Natural resistance against infections: focus on COVID-19	37
Astrocytes ACLYmate to chronic neuroinflammation	37
Subscription and Copyright Information	37
Balancing IL-17–mediated protection and IFN-γ–driven pathology at mucocutaneous barriers	36
Intracellular C1q – an unexpected player in neuronal proteostasis	36
Advisory Board and Contents	36
Chopped! Newfound GSDMD cleavage facilitates tolerance to food allergens	35
Subscription and Copyright Information	35
Subscription and Copyright Information	35
Original antigenic sin: not so sinful after all	35
B cells masquerade as dendritic cells	34
Subscription and Copyright Information	33
Mitochondrial dysfunction in myeloid cells: a central deficit in autoimmune diseases	33
Immunology as a guide to human relationships	33
Antigen presentation by MHC-E: a putative target for vaccination?	32
Interleukin-22: the hub bridging gut homeostasis and metabolism	32
Bridging anatomical gaps between brain and immune system	31
Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments	31
Monoallelic expression in human immune cells: linking genotype to phenotype	30
TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus	30
Calreticulin surface presentation can promote quality control of hematopoietic stem cells	30
Old macrophages lose their (circadian) rhythm	30
Lymphoid tissue on the mind	30
Subscription and Copyright Information	30
LNCing RNA to immunity	29
Spiking SARS-CoV-2 antiviral immunity in the respiratory tract	29

The complex immunological role of Helicobacter in modulating cancer	28
Transcription factor-driven regulation of ILC1 and ILC3	28
Emerging roles for tRNAs in hematopoiesis and hematological malignancies	28
Advisory Board and Contents	27
Advisory Board and Contents	27
Protists protecting food tolerance	27
Signaling is the pathway to macrophage function	27
Advisory Board and Contents	27
Subscription and Copyright Information	27
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers	26
Chimeric antigen receptor Treg therapy in transplantation	26
Targeting the metabolism of tumor-infiltrating regulatory T cells	26
Advisory Board and Contents	25
Overcoming gender bias in STEM	25
Using structure-function information from IFN-γ-binding proteins and biased agonists to uncouple immunostimulatory and immunosuppressive activities	25
Gut microbiota–host post-translational modification axis in immunometabolic diseases	25
Immune-featured decidual stromal cells: pregnancy's multitasking superstars	25
Putative role of STING-mitochondria associated membrane crosstalk in immunity	25
Protect, repair, rewire, and defend	25
Subscription and Copyright Information	25
Exploring mucosal immune development and function in utero	25
Multiple sclerosis: role of meningeal lymphoid aggregates in progression independent of relapse activity	24
Harder, better, faster, stronger: biochemistry and biophysics in the immunosurveillance concert	24
Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy	24
Subscription and Copyright Information	24
New insights into innate immunity in Alzheimer’s disease: from APOE protective variants to therapies	24
Advisory Board and Contents	24
Immunotherapy response-associated Akkermansia: canary in a coal mine?	22
The predictive power of systems immunology	22
TCR-sequencing in cancer and autoimmunity: barcodes and beyond	21
Sensory neuronal control of skin barrier immunity	21
Sensory nerves unlock the TOLL-7 gate for cancer spread	21
Regulation and impact of tumor-specific CD4+ T cells in cancer and immunotherapy	20
The diversity of cGLR receptors: shedding new light on innate immunity	20
How do autoimmune CD4+ T cells handle exhaustion?	20
Subscription and Copyright Information	20
Th17 cells: from gut homeostasis to CNS pathogenesis	20
BCG vaccination induces cross-protective immunity against pathogenic microorganisms	20
CD8+ Tregs kill pathogenic cells to avert autoimmunity	20
COVID-19 thromboinflammation: adding inflammatory fibrin to the puzzle	19
Feeding the wrath with myelin	19
Repurposing of old drugs for unleashing innate immunity	19
Partners and guardians of the nervous and immune systems	19
SARS-CoV-2 evolution from the BA.2.86 to JN.1 variants: unexpected consequences	19
Development of a circadian immune system	19
Inflammasome diversity: exploring novel frontiers in the innate immune response	18
Lymph node fibroblast-produced extracellular matrix shapes immune function	18
Life and death of tolerogenic dendritic cells	18
The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases	18
Post-translational modifications of NLRP3: to prime or not to prime?	17
Human neutrophil kinetics: a call to revisit old evidence	17
cGAS-like receptors: back to the future	17
The extracellular matrix and immunity: breaking the old barrier in cancer	17
News from the T cell trogocytosis front	17
Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment	17
B cell phylogenetics in the single cell era	17
Finding your niche: immune evasion in quiescent tumor reservoirs	17
Breaking down IgA: Tomasiella immunophila enlightens microbiome–immune interactions	16
Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity	16
Early clues regarding the pathogenesis of long-COVID	16
Melanoma-derived mediators can foster the premetastatic niche: crossroad to lymphatic metastasis	16
Advisory Board and Contents	15
Neuro–immune crosstalk: focus on innate lymphoid cells	15
Restriction factors regulating human herpesvirus infections	15
Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice	15
Molecular mimicry as a driver of T cell-mediated tumour immunity	15
Inflammasomopathies: mechanisms and disease signatures	14
Physiological role of cytokines in the regulation of mammalian metabolism	14
Unraveling B cell trajectories at single cell resolution	14
Exhausted CD8+ T cells face a developmental fork in the road	14
Turning cold tumors hot: from molecular mechanisms to clinical applications	14
Macrophage states: there's a method in the madness	14
ICOS-play: dressing T cells for residency	14
RNA circuits and RNA-binding proteins in T cells	14
Zebrafish: an underutilized tool for discovery in host–microbe interactions	14