Trends in Immunology

Article	Citations
Subscription and Copyright Information	507
Advisory Board and Contents	421
Subscription and Copyright Information	413
Advisory Board and Contents	231
Advisory Board and Contents	206
Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2	168
Tensor-based insights into systems immunity and infectious disease	165
On tending sprouts: empowering emerging immunologists in Latin America	165
‘Smelling’ lipid cues: chemosensory receptors tune tumor-associated macrophage behavior	135
Contribution of gut-derived T cells to extraintestinal autoimmune diseases	124
Metabolic and stress response adaptations in T cells to fever and physiological heat	103
Type 2 conventional dendritic cell functional heterogeneity: ontogenically committed or environmentally plastic?	97
Innate immunity: the bacterial connection	95
Novel insights and recent progress in osteoimmunology	91
DNA flexibility can shape the preferential hypermutation of antibody genes	88
Dietary fibers affecting gastrointestinal immunity	76
Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine	74
Beyond the innate immune system: rethinking inflammasomes in multiple sclerosis	71
Generalized pustular psoriasis: immunological mechanisms, genetics, and emerging therapeutics	69
DNA at the center of mammalian innate immune recognition of bacterial biofilms	69
Oxidative battles in tuberculosis: walking the ferroptotic tightrope	68
Loss of ARID1A ‘loops’ in STING	67
Subscription and Copyright Information	64
EmBmem: will the real memory B cell please stand up?	64
Targeting WSTF degradation to resolve chronic inflammation	61

Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy?	61
BCR signaling in germinal center B cell selection	54
Inflammatory and immune etiology of type 2 diabetes	51
The tumor niche can reprogram long-lived protumorigenic neutrophils	50
Homeostatic chemokines as putative therapeutic targets in idiopathic pulmonary fibrosis	50
Trained immunity-based mucosal immunotherapies for the prevention of respiratory infections	49
Infusion of neutralization into Lassa vaccine design	48
Advisory Board and Contents	48
Risk factors of cytokine release syndrome: stress, catecholamines, and beyond	48
Unanticipated specificity in effector-triggered immunity	47
High endothelial venules as potential gateways for therapeutics	46
Cytosolic delivery of innate immune agonists	46
Leveraging community engagement to shape biomedical research priorities	45
Agents of cancer immunosurveillance: HSPs and dsDNA	45
Subscription and Copyright Information	44
Genotype–phenotype landscapes for immune–pathogen coevolution	44
Context-dependent regulation of follicular helper T cell survival	43
The five senses of immunity	42
Tumor microenvironment metabolites directing T cell differentiation and function	41
The translational potential of studying bat immunity	40
Targeting Th17 cells in HIV-1 remission/cure interventions	39
Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology	38
Microglia as integrators of brain-associated molecular patterns	37
Subscription and Copyright Information	37
Maternal inflammation and its ramifications on fetal neurodevelopment	37
B cells masquerade as dendritic cells	36
Astrocytes ACLYmate to chronic neuroinflammation	36
Balancing IL-17–mediated protection and IFN-γ–driven pathology at mucocutaneous barriers	36
Subscription and Copyright Information	35
Subscription and Copyright Information	35
Original antigenic sin: not so sinful after all	35
Advisory Board and Contents	35
Subscription and Copyright Information	35
Chopped! Newfound GSDMD cleavage facilitates tolerance to food allergens	34
Immunology as a guide to human relationships	33
Interleukin-22: the hub bridging gut homeostasis and metabolism	33
Mitochondrial dysfunction in myeloid cells: a central deficit in autoimmune diseases	33
Bridging anatomical gaps between brain and immune system	32
Antigen presentation by MHC-E: a putative target for vaccination?	32
Intracellular C1q – an unexpected player in neuronal proteostasis	32
Spiking SARS-CoV-2 antiviral immunity in the respiratory tract	31
Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments	31
Monoallelic expression in human immune cells: linking genotype to phenotype	31
Natural resistance against infections: focus on COVID-19	31
The complex immunological role of Helicobacter in modulating cancer	30
Emerging roles for tRNAs in hematopoiesis and hematological malignancies	30
Old macrophages lose their (circadian) rhythm	29
TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus	29
Lymphoid tissue on the mind	29
Calreticulin surface presentation can promote quality control of hematopoietic stem cells	29

Advisory Board and Contents	28
LNCing RNA to immunity	28
Targeting γδ T cells for immunotherapies against colorectal cancer	28
Subscription and Copyright Information	28
Subscription and Copyright Information	28
Transcription factor-driven regulation of ILC1 and ILC3	28
Advisory Board and Contents	27
Signaling is the pathway to macrophage function	27
Advisory Board and Contents	27
Exploring mucosal immune development and function in utero	26
Using structure-function information from IFN-γ-binding proteins and biased agonists to uncouple immunostimulatory and immunosuppressive activities	26
Gut microbiota–host post-translational modification axis in immunometabolic diseases	26
Protists protecting food tolerance	26
Advisory Board and Contents	25
Putative role of STING-mitochondria associated membrane crosstalk in immunity	25
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers	25
The lingering shadow of epidemics: post-acute sequelae across history	25
Immune-featured decidual stromal cells: pregnancy's multitasking superstars	25
Targeting the metabolism of tumor-infiltrating regulatory T cells	25
Chimeric antigen receptor Treg therapy in transplantation	25
Protect, repair, rewire, and defend	24
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Th17 cells: from gut homeostasis to CNS pathogenesis	23
Harder, better, faster, stronger: biochemistry and biophysics in the immunosurveillance concert	22
Advisory Board and Contents	22
Advisory Board and Contents	22
The predictive power of systems immunology	22
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Immunotherapy response-associated Akkermansia: canary in a coal mine?	22
Overcoming gender bias in STEM	21
Sensory nerves unlock the TOLL-7 gate for cancer spread	21
TCR-sequencing in cancer and autoimmunity: barcodes and beyond	21
Multiple sclerosis: role of meningeal lymphoid aggregates in progression independent of relapse activity	21
Sensory neuronal control of skin barrier immunity	21
New insights into innate immunity in Alzheimer’s disease: from APOE protective variants to therapies	20
Lactation, tissue-resident immunity, and protection against breast cancer	20
Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy	20
Regulation and impact of tumor-specific CD4+ T cells in cancer and immunotherapy	20
How do autoimmune CD4+ T cells handle exhaustion?	20
BCG vaccination induces cross-protective immunity against pathogenic microorganisms	20
The diversity of cGLR receptors: shedding new light on innate immunity	19
Development of a circadian immune system	19
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Partners and guardians of the nervous and immune systems	19
Repurposing of old drugs for unleashing innate immunity	19
CD8+ Tregs kill pathogenic cells to avert autoimmunity	19
Feeding the wrath with myelin	19
B cell phylogenetics in the single cell era	18
COVID-19 thromboinflammation: adding inflammatory fibrin to the puzzle	18
SARS-CoV-2 evolution from the BA.2.86 to JN.1 variants: unexpected consequences	18
Lymph node fibroblast-produced extracellular matrix shapes immune function	18
The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases	18
Early clues regarding the pathogenesis of long-COVID	17
Melanoma-derived mediators can foster the premetastatic niche: crossroad to lymphatic metastasis	17
Post-translational modifications of NLRP3: to prime or not to prime?	17
Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment	17
Inflammasome diversity: exploring novel frontiers in the innate immune response	17
Life and death of tolerogenic dendritic cells	17
Finding your niche: immune evasion in quiescent tumor reservoirs	16
News from the T cell trogocytosis front	16
cGAS-like receptors: back to the future	16
Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity	15
Breaking down IgA: Tomasiella immunophila enlightens microbiome–immune interactions	15
Human neutrophil kinetics: a call to revisit old evidence	15
The extracellular matrix and immunity: breaking the old barrier in cancer	15
Advisory Board and Contents	15
ICOS-play: dressing T cells for residency	14
Restriction factors regulating human herpesvirus infections	14
Molecular mimicry as a driver of T cell-mediated tumour immunity	14
Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice	14
Neuro–immune crosstalk: focus on innate lymphoid cells	14
Physiological role of cytokines in the regulation of mammalian metabolism	13
Unraveling B cell trajectories at single cell resolution	13
A microbiota-derived antigen drives CD4+ intraepithelial lymphocyte (CD4IEL) development	13
Inflammasomopathies: mechanisms and disease signatures	13
Exhausted CD8+ T cells face a developmental fork in the road	13
Turning cold tumors hot: from molecular mechanisms to clinical applications	13
T cell TET2 disruption cuts the breaks on antitumor CAR T cell therapy	13
RNA circuits and RNA-binding proteins in T cells	13
Macrophage states: there's a method in the madness	13

Single-dose HPV vaccine immunity: is there a role for non-neutralizing antibodies?	13
New insights into transcription elongation control of HIV-1 latency and rebound	13
Advisory Board and Contents	12
Interferon-stimulated gene IFI27 as a multifaceted candidate target in precision medicine	12
Channel plan: control of adaptive immune responses by pannexins	12
IEL–IEC circuit in barrier immunity and beyond	12
Prenatal inflammation shapes microglial immune response into adulthood	12
Cancer germline antigens and tumor-agnostic CD8+ T cell evasion	12
Advisory Board and Contents	12
Zebrafish: an underutilized tool for discovery in host–microbe interactions	12
The T cell subsetting challenge	12
Uniting innate and adaptive immunity in glioblastoma; an α-CTLA-4 quest	12
Cryptic but critical: non-canonical antigens in cancer immunotherapy	11
Advisory Board and Contents	11
Subscription and Copyright Information	11
Monoclonal antibodies lock down SARS-CoV-2 spike	11
Inflammatory and immune effects on tumor progression	11
Advisory Board and Contents	11
Towards a quantitative theory of tolerance	10
Ghrelin and leptin regulating wound healing	10
Enhancing tumor immunity via in vivo cDC1 reprogramming	10
Locus architecture and RAG scanning determine antibody diversity	10
Affinity-independent plasma cell differentiation in germinal centers	10
Using TCR-CAR dual signaling for precise cancer targeting	10
Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond	9
Introducing the 'Significance' box in Trends in Immunology articles	9
Cell intrinsic versus cell extrinsic control of plasma cell longevity	9
Approaches for studying neuroimmune interactions in Alzheimer’s disease	9
Aching to defend: spleen innervation drives humoral immunity	9
Humans pIKK-up NLRP3 to skip NEK7	9
SARS-CoV-2 vaccination washes away original antigenic sin	9
Microglia replacement: from monocytic origin to therapy	8
Developing cultural humility in immunology and STEMM mentoring	8
Targeting immune evasion in hepatocellular carcinoma-initiating cells	8
Regional specialization within the mammalian respiratory immune system	8
Advisory Board and Contents	8
Mutagenic repair during antibody diversification: emerging insights	8
Deciphering SARS-CoV-2 evolution under antibody immune pressure	8
Malaria: influence of Anopheles mosquito saliva on Plasmodium infection	8
Extracellular vesicles transport gasdermin pores, amplifying inflammatory cell death	8
Multiscale geometric and topological analyses for characterizing and predicting immune responses from single cell data	8
Germinal centre B cell disruption by non-typhoidal Salmonella	7
Genetic conflicts and the origin of self/nonself-discrimination in the vertebrate immune system	7
Subscription and Copyright Information	7
ADAR1 and ZBP1 in innate immunity, cell death, and disease	7
Maternal diet shapes the development and identity of tissue-resident macrophages	7
Gutsy sensations modulate intestinal disease	7
Pseudomonas aeruginosa: a pathogen making itself at home	7
Microglia pack a toolbox for life	7
Advisory Board and Contents	7
Enlightening Per2-suasive role of neutrophils in antibacterial immunity	7
Subscription and Copyright Information	7
Memory B cell diversity: insights for optimized vaccine design	7
Structure-based mechanisms of 2′3′-cGAMP intercellular transport in the cGAS–STING immune pathway	7
Embryonic microglia maintain the brain's cortical fault lines	7
The heightened importance of the microbiome in cancer immunotherapy	6
Boosting peripheral immunity to fight neurodegeneration in the brain	6
Advisory Board and Contents	6
Get with the program: regulation of T cell death	6
The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder	6
The Vibrio cholerae maneuver	6
Lung tumor immunity: redirecting macrophages through infection-induced inflammation	6
Why do central nervous system barriers host a diverse immune landscape?	6
Decoding microglial functions in Alzheimer’s disease: insights from human models	6
Leveraging deep learning to improve vaccine design	6
Complement(ing) long-COVID thromboinflammation and pathogenesis	6
Diet and immune response: how today’s plate shapes tomorrow’s health	6
Epigenetically programmed identity crisis to combat diffuse large B cell lymphoma	6
Neuronal inflammasomes: balancing immunity, neuroinflammation, and homeostasis	6
Transcriptional control of natural killer cell antitumor activity	6
Over but not gone: lingering epigenetic effects of COVID-19	6
Macrophage immunotherapy: overcoming impediments to realize promise	6
Deconstructing iNKT cell development at single-cell resolution	6
Tracking tumor-specific CD8+ T cell responses	6
Modeling human immune responses to vaccination in vitro	6
Approaches for studying human macrophages	6
Recombinant snake antivenoms get closer to the clinic	6
The putative contribution of cellular senescence to driving tauopathies	6
Helper ILCs in the human hematopoietic system	6
Towards decoding the space-time continuum of pregnancy	6
Immunomodulatory impact of α-fetoprotein	6
NF-κB: blending metabolism, immunity, and inflammation	6
Allogeneic hematopoietic stem cell transplantation: lessons learned by a molecular immunologist/transplant patient	6
Mitochondrial lipid metabolism in tumor immunosurveillance and evasion	5
A novel mechanism of immunoevasion by ER+ breast cancer	5
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A mother's touch: microbial guardians of early immune imprinting	5
Restraining the killers: regulation of T cell quiescence	5
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Base editors dissect genetic variants in human hematopoietic cells on a large scale	5
The Janus face of NK cells in neurodevelopment	5
One degree of separation: urgent questions surrounding new USA laws in women’s healthcare	5
Advisory Board and Contents	5
ZBTB46 in ILC3: shared transcriptional infrastructure defines gut-protective capabilities	5
Nanotube-mediated mitochondrial transfer: power to the T cells!	5