Trends in Immunology

Article	Citations
Advisory Board and Contents	283
Advisory Board and Contents	267
Type 2 conventional dendritic cell functional heterogeneity: ontogenically committed or environmentally plastic?	233
Subscription and Copyright Information	219
Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy	135
Structure-based mechanisms of 2′3′-cGAMP intercellular transport in the cGAS–STING immune pathway	123
K63 ubiquitination in immune signaling	112
Lymph node stromal cells: subsets and functions in health and disease	110
Immunotherapy response-associated Akkermansia: canary in a coal mine?	103
Odorant receptors in macrophages: potential targets for atherosclerosis	102
DNA flexibility can shape the preferential hypermutation of antibody genes	102
Immune-featured decidual stromal cells: pregnancy's multitasking superstars	90
γδ T cells unveil invisible tumors	89
Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2	88
Advisory Board and Contents	82
Subscription and Copyright Information	78
Advisory Board and Contents	78
Mutagenic repair during antibody diversification: emerging insights	76
Targeting metabolic pathways to counter cancer immunotherapy resistance	75
Developing pan-β-coronavirus vaccines against emerging SARS-CoV-2 variants of concern	74
Factors contributing to the potency of CD8+ T cells	69
Advisory Board and Contents	69
Multiple sclerosis: role of meningeal lymphoid aggregates in progression independent of relapse activity	59
Emerging roles of Dectin-1 in noninfectious settings and in the CNS	59
Microglia pack a toolbox for life	54

Advisory Board and Contents	51
Protean Regulation of Leukocyte Function by Nuclear Lamins	51
Advisory Board and Contents	51
Sensory neuronal control of skin barrier immunity	51
ADAR1 entraps sinister cellular dsRNAs, thresholding antiviral responses	48
Overcoming gender bias in STEM	48
Advisory Board and Contents	46
The predictive power of systems immunology	45
Subscription and Copyright Information	43
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Genetic conflicts and the origin of self/nonself-discrimination in the vertebrate immune system	42
Gutsy sensations modulate intestinal disease	41
Novel approaches to preventing phagosomal infections: timing is key	40
Th17 cells: from gut homeostasis to CNS pathogenesis	38
Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye	37
Metabolites and secretory immunoglobulins: messengers and effectors of the host–microbiota intestinal equilibrium	37
Dietary fibers affecting gastrointestinal immunity	36
Autoimmune thyroid diseases as a cost of physiological autoimmune surveillance	35
Erythrocyte-derived mitochondria: an unexpected interferon inducer in lupus	35
Innate immunity: the bacterial connection	35
Neuro-immune crosstalk in hematopoiesis, inflammation, and repair	34
Do antigen-presenting CD1a, CD1b, CD1c, and CD1d molecules bind different self-lipids?	34
De-stressing plaques attenuates atherosclerosis progression	33
Monocyte Regulation in Homeostasis and Malignancy	33
Tonsil organoids: peering down the throat of human immunity	33
VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy	33
Uncloaking Breast Tumor Neoantigens with Radiation	32
Conservation and divergence in gene regulation between mouse and human immune cells deserves equal emphasis	32
Pseudomonas aeruginosa: a pathogen making itself at home	32
Reframing macrophage diversity with network motifs	31
Gasdermin D palmitoylation: to cleave or not to cleave?	31
Harder, better, faster, stronger: biochemistry and biophysics in the immunosurveillance concert	31
Ragulator-Rag and ROS TORment gasdermin D pore formation	30
Tensor-based insights into systems immunity and infectious disease	30
Regulation and impact of tumor-specific CD4+ T cells in cancer and immunotherapy	29
Friendly fungi: symbiosis with commensal Candida albicans	28
Antibody-mediated regulation of basophils: emerging views and clinical implications	28
Memory B cell diversity: insights for optimized vaccine design	28
The impact of age-related hypomethylated DNA on immune signaling upon cellular demise	27
Gata6+ large peritoneal macrophages: an evolutionarily conserved sentinel and effector system for infection and injury	27
Systems immunology insights into brain metastasis	26
Sensory nerves unlock the TOLL-7 gate for cancer spread	26
Myeloid cells take ischemic insult to heart	26
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Protect, repair, rewire, and defend	26
ADAR1 and ZBP1 in innate immunity, cell death, and disease	25
APOE4 affects neutrophil–microglia crosstalk in Alzheimer’s disease	25
TCR-sequencing in cancer and autoimmunity: barcodes and beyond	25
BCG vaccination induces cross-protective immunity against pathogenic microorganisms	25
Novel insights into the dynamic function of PRC2 in innate immunity	25

New insights into innate immunity in Alzheimer’s disease: from APOE protective variants to therapies	25
Contribution of gut-derived T cells to extraintestinal autoimmune diseases	24
The NLRP3 inflammasome: regulation by metabolic signals	24
Decoding the dynamics of multilayered stochastic antiviral IFN-I responses	23
Parkinson's disease: connecting mitochondria to inflammasomes	22
Shaped by the epithelium – postnatal immune mechanisms of oral homeostasis	22
Multiscale geometric and topological analyses for characterizing and predicting immune responses from single cell data	22
miRNA effects on gut homeostasis: therapeutic implications for inflammatory bowel disease	21
Acute Lymphoblastic Leukemia Cell Lines in Immunology Research	21
Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks	21
Emerging mechanisms of immunocoagulation in sepsis and septic shock	21
Mind the GAP: RASA2 and RASA3 GTPase-activating proteins as gatekeepers of T cell activation and adhesion	21
Advisory Board and Contents	20
Advisory Board and Contents	20
Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity	20
Cellular RNA acts as an antiviral MAVS signalosome scaffold	19
Targeting immune evasion in hepatocellular carcinoma-initiating cells	19
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Sodium and its manifold impact on our immune system	18
EmBmem: will the real memory B cell please stand up?	18
VAV1 as a putative therapeutic target in autoimmune and chronic inflammatory diseases	18
DNA at the center of mammalian innate immune recognition of bacterial biofilms	18
Advisory Board and Contents	18
Loss of ARID1A ‘loops’ in STING	18
Embryonic microglia maintain the brain's cortical fault lines	18
Gasdermin D triggers cardiolipin-driven mitochondrial damage and pyroptosis	18
Advisory Board and Contents	17
The Immunologists’ Guide to Pandemic Preparedness	17
Immunological features of bats: resistance and tolerance to emerging viruses	17
Uncovering the genomic toll of the Black Death	17
The Vibrio cholerae maneuver	17
Is α1-Antitrypsin Important for Murine Thymocyte Development?	17
A variegated model of transcription factor function in the immune system	17
α1-Antitrypsin Causing CD8 Downregulation during Thymocyte Differentiation	17
Lipocalin-2: a novel potential therapy for GVHD	16
Cell death checkpoints in the TNF pathway	16
To eat or not to eat: type 2 immunity controls food avoidance behavior	16
Inflammasome diversity: exploring novel frontiers in the innate immune response	16
Complement: you gutsy thing!	16
NF-κB dynamics in the language of immune cells	16
Over but not gone: lingering epigenetic effects of COVID-19	15
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NLRP12 drives PANoptosis in response to heme	15
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Does delayed EBV infection contribute to rising childhood cancers?	15
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The tumor niche can reprogram long-lived protumorigenic neutrophils	14
Generalized pustular psoriasis: immunological mechanisms, genetics, and emerging therapeutics	14
Rationalizing Random Walks: Replicating Protective Antibody Trajectories	14
Hic et Runx: new insights into T cell tissue residency	14
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Partners and guardians of the nervous and immune systems	13
CD8+ Tregs kill pathogenic cells to avert autoimmunity	13
The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases	13
Enemy or ally? Fasting as an essential regulator of immune responses	13
Immunomodulatory impact of α-fetoprotein	13
Astrocyte interleukin-3 preps microglia	13
How do autoimmune CD4+ T cells handle exhaustion?	13
Weapon of choice: viruses share cross-kingdom tools	12
Spatial features of skip lesions in Crohn’s disease	12
Stepping up Th1 immunity to control phagosomal bacteria	12
Carbohydrates in allergy: from disease to novel immunotherapies	11
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Hematopoiesis in numbers	11
Advisory Board and Contents	11
Context-Dependent Glioblastoma–Macrophage/Microglia Symbiosis and Associated Mechanisms	11
Early Events Triggering the Initiation of a Type 2 Immune Response	11
Programming cytomegalovirus as an HIV vaccine	10
New insights into TCR β-selection	10
C3-targeted therapy in periodontal disease: moving closer to the clinic	10
The Roles of T cells in Bladder Pathologies	10
pH sensing at the intersection of tissue homeostasis and inflammation	10
Advisory Board and Contents	10
RORγt protein modifications and IL-17-mediated inflammation	9
Macrophages marc(o) the difference in liver inflammation?	9
The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder	9
The putative contribution of cellular senescence to driving tauopathies	9
The diversity of cGLR receptors: shedding new light on innate immunity	9
NAD+ in COVID-19 and viral infections	9

B cell phylogenetics in the single cell era	9
Feeding the wrath with myelin	9
Linking nutrient sensing, mitochondrial function, and PRR immune cell signaling in liver disease	9
Innate antiviral immunity: how prior exposures can guide future responses	9
Carbohydrates as putative pattern recognition receptor agonists in vaccine development	9
Predicting and Preventing Immune Checkpoint Inhibitor Toxicity: Targeting Cytokines	9
Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine	9
Recombinant snake antivenoms get closer to the clinic	8
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SARS-CoV-2 evolution from the BA.2.86 to JN.1 variants: unexpected consequences	8
Towards regulatory cellular therapies in solid organ transplantation	8
Disease-associated oligodendroglia: a putative nexus in neurodegeneration	8
Risk factors of cytokine release syndrome: stress, catecholamines, and beyond	8
‘Silent’ flagellin drives immunotolerance to commensal bacteria	8
COVID-19 thromboinflammation: adding inflammatory fibrin to the puzzle	8
Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH)	8
Targeting neuraminidase: the next frontier for broadly protective influenza vaccines	8
The ‘cytokine storm’: molecular mechanisms and therapeutic prospects	7
Deregulation of enhancer structure, function, and dynamics in acute lymphoblastic leukemia	7
Mouse gut blueprint: regionality and resilience	7
Inflammatory and immune etiology of type 2 diabetes	7
Monocyte differentiation within tissues: a renewed outlook	7
Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis	7
BCR signaling in germinal center B cell selection	7
Life and death of tolerogenic dendritic cells	7
Differential roles of interferons in innate responses to mucosal viral infections	7
Innate-like T cells in liver disease	7
Ligand-restricted synNotch switches enable precision cell therapy	7
Homeostatic chemokines as putative therapeutic targets in idiopathic pulmonary fibrosis	7
Advisory Board and Contents	6
Thymic mimetic cells: tolerogenic masqueraders	6
Advisory Board and Contents	6
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Genotype–phenotype landscapes for immune–pathogen coevolution	6
Advisory Board and Contents	6
Leveraging deep learning to improve vaccine design	6
T-bet+ B cells exacerbate obesity-related metabolic disease	6
Advisory Board and Contents	6
Allogeneic hematopoietic stem cell transplantation: lessons learned by a molecular immunologist/transplant patient	6
Apart, together: coping with the COVID-19 pandemic	6
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Tissue-specific differentiation of CD8+ resident memory T cells	6
Context-dependent regulation of follicular helper T cell survival	6
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COVID-19 vaccines and a perspective on Africa	6
Deconstructing iNKT cell development at single-cell resolution	5
Obesity and dysregulated innate immune responses: impact of micronutrient deficiencies	5
Impact of human CD95 mutations on cell death and autoimmunity: a model	5
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Durable CD4+ T cell immunity: cherchez la stem	5
cGAS-like receptors: back to the future	5
Nanocarrier design for pathogen-inspired innate immune agonist delivery	5
IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy	5
Staggered starts in the race to T cell activation	5
The extracellular matrix and immunity: breaking the old barrier in cancer	5
The translational potential of studying bat immunity	5
Gland Macrophages: Reciprocal Control and Function within Their Niche	5
Unmasking the hidden impact of viruses on tuberculosis risk	5
Targeting Th17 cells in HIV-1 remission/cure interventions	5
Human neutrophil kinetics: a call to revisit old evidence	5
Oxidative stress, malaria, sickle cell disease, and innate immunity	5
Why are there so few (or so many) circulating coronaviruses?	5
Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment	5
Tracking tumor-specific CD8+ T cell responses	5
Melanoma-derived mediators can foster the premetastatic niche: crossroad to lymphatic metastasis	4
A new model of human lymphopoiesis across development and aging	4
Systems immunology of regulatory T cells: can one circuit explain it all?	4
Hypoxia and HIF-1 as key regulators of gut microbiota and host interactions	4
Finding your niche: immune evasion in quiescent tumor reservoirs	4
An immune window of opportunity to prevent childhood B cell leukemia	4
The many ways in which alphaviruses bind to cells	4
Double-take: SARS-CoV-2 has evolved to evade human innate immunity, twice	4
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Basophil differentiation, heterogeneity, and functional implications	4
Towards decoding the space-time continuum of pregnancy	4
Modeling human immune responses to vaccination in vitro	4
Advisory Board and Contents	3
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Maternal inflammation and its ramifications on fetal neurodevelopment	3
Type 2 immunity: a two-edged sword in schistosomiasis immunopathology	3
Early clues regarding the pathogenesis of long-COVID	3
High endothelial venules as potential gateways for therapeutics	3
Why do central nervous system barriers host a diverse immune landscape?	3
Boosting peripheral immunity to fight neurodegeneration in the brain	3
Unanticipated specificity in effector-triggered immunity	3
Macrophage immunotherapy: overcoming impediments to realize promise	3
Approaches for studying human macrophages	3
The heightened importance of the microbiome in cancer immunotherapy	3
Complement(ing) long-COVID thromboinflammation and pathogenesis	3
Will cellular immunotherapies end neurodegenerative diseases?	3
Engineering immunity: bacterial delivery of cancer neoantigen vaccines	3
Cytosolic delivery of innate immune agonists	3
Agents of cancer immunosurveillance: HSPs and dsDNA	3
The emergence of cancer sono-immunotherapy	3
Diet and immune response: how today’s plate shapes tomorrow’s health	3