Current Opinion in Pharmacology

Article	Citations
The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases	64
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus	63
Nanotechnology in pulmonary medicine	55
Gestational diabetes: Implications for fetal growth, intervention timing, and treatment options	48
Prospects for COPD treatment	47
Targeting fibroblast-like synoviocytes in rheumatoid arthritis	45
Targeting B cells for inflammatory bowel disease treatment: back to the future	42
The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids	42
Transforming targeted cancer therapy with PROTACs: A forward-looking perspective	41
Current advances in the treatment of systemic sclerosis	41
Antihypertensive effect of soybean bioactive peptides: A review	36
A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury	35
Role of HSV-1 in Alzheimer's disease pathogenesis: A challenge for novel preventive/therapeutic strategies	34
The role of the liver in the modulation of glucose and insulin in non alcoholic fatty liver disease and type 2 diabetes	32
Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications	32
Astrocytes as cellular mediators of cue reactivity in addiction	32
Glutamate receptors and metaplasticity in addiction	31
Circadian control of human cardiovascular function	30
Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance	29
Monitoring vedolizumab and ustekinumab drug levels in patients with inflammatory bowel disease: hype or hope?	28
Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis	27
N-methyl-d-aspartate receptor function in neuronal and synaptic development and signaling	27
Treatment of early rheumatoid arthritis: Methotrexate and beyond	26
Does probiotics work for bacterial vaginosis and vulvovaginal candidiasis	25
Treatments for COVID-19: Lessons from 2020 and new therapeutic options	25

Exercise as a drug for glucose management and prevention in type 2 diabetes mellitus	25
Alpha1-antitrypsin deficiency: New therapies on the horizon	25
Chronotherapy of cardiac and vascular disease: timing medications to circadian rhythms to optimize treatment effects and outcomes	25
Applications of chemogenetics in non-human primates	24
The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy	24
The role of faecal microbiota transplantation in the treatment of inflammatory bowel disease	23
Role of intestinal glucose absorption in glucose tolerance	23
Circadian influence on inflammatory response during cardiovascular disease	23
Photopharmacological control of cell signaling with photoswitchable lipids	23
Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder	23
Intersection of immunometabolism and immunosenescence during aging	22
Effects of functional electrical stimulation on muscle health after spinal cord injury	22
The changing landscape of the cystic fibrosis lung environment: From the perspective of Pseudomonas aeruginosa	21
Testosterone therapy for prevention and reversal of type 2 diabetes in men with low testosterone	21
Rethinking the clinical management of volumetric muscle loss in patients with spinal cord injury: Synergy among nutritional supplementation, pharmacotherapy, and rehabilitation	21
Current state of CFTR modulators for treatment of Cystic Fibrosis	21
Updated pharmacological effects of Lonicerae japonicae flos, with a focus on its potential efficacy on coronavirus disease–2019 (COVID-19)	21
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis	21
Environmental enrichment-inspired pharmacological tools for the treatment of addiction	20
Adoptive cell therapy for solid tumors: Chimeric antigen receptor T cells and beyond	20
The 2013–2016 Ebola virus disease outbreak in West Africa	19
New drugs in the pipeline for the treatment of inflammatory bowel diseases: what is coming?	19
Optical control of Class A G protein-coupled receptors with photoswitchable ligands	18
The e-psychonaut drugs’ psychopharmacology	17
Prospects for severe asthma treatment	17
Cost-effectiveness of therapeutic drug monitoring in inflammatory bowel disease	17
Recent advances in emerging PCOS therapies	17
Stress, kisspeptin, and functional hypothalamic amenorrhea	17
Immunogenicity, breakthrough infection, and underlying disease flare after SARS-CoV-2 vaccination among individuals with systemic autoimmune rheumatic diseases	17
Pharmacological modulation of GABAA receptors	17
Genetic risk scores and personalization of care in fatty liver disease	17
Non-alcoholic fatty liver disease: Current therapeutic options	17
Lipid deposition and metaflammation in diabetic kidney disease	17
Probing function in 3D neuronal cultures: A survey of 3D multielectrode array advances	17
Metabokines in the regulation of systemic energy metabolism	17
Hormonal drugs for the treatment of endometriosis	17
The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: A mini-review of the potential mechanisms	17
Ubiquitin proteasome system in immune regulation and therapeutics	16
Pharmacologic approaches to prevent skeletal muscle atrophy after spinal cord injury	16
Muscle multiorgan crosstalk with MG53 as a myokine for tissue repair and regeneration	16
Elexacaftor–tezacaftor–ivacaftor: The new paradigm to treat people with cystic fibrosis with at least one p.Phe508del mutation	16
Microbiota-gut-brain axis: A novel potential target of ketogenic diet for epilepsy	16
Lynx1 prototoxins: critical accessory proteins of neuronal nicotinic acetylcholine receptors	16
Targeting cellular senescence as a novel treatment for osteoarthritis	15
The hypodopaminergic state ten years after: transcranial magnetic stimulation as a tool to test the dopamine hypothesis of drug addiction	15
Tackling inflammation in atherosclerosis: Are we there yet and what lies beyond?	15
Three-dimensional culture models to study glioblastoma — current trends and future perspectives	15
Recent insights into astrocytes as therapeutic targets for demyelinating diseases	14
Immune dysfunction after spinal cord injury – A review of autonomic and neuroendocrine mechanisms	14
Targeting PKC in microglia to promote remyelination and repair in the CNS	14

Targeting drug memory reconsolidation: a neural analysis	14
Pharmacology of pannexin channels	14
Recent developments and strategies of Ebola virus vaccines	14
Overview of CF lung pathophysiology	13
Targeting cellular senescence as a new approach to chronic obstructive pulmonary disease therapy	13
Role of fibro-adipogenic progenitor cells in muscle atrophy and musculoskeletal diseases	13
Current pharmacological treatment of hepatocellular carcinoma	13
Potential mechanisms of macular degeneration protection by fatty fish consumption	13
Old and new biomarkers for volumetric muscle loss	13
Emerging strategies for treating gout	13
Molecular routes to sarcopenia and biomarker development: per aspera ad astra	13
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers	13
Smad-dependent pathways in the infarcted and failing heart	13
Highland mate: Edible and functional foods in traditional medicine for the prevention and treatment of hypoxia-related symptoms	13
Promising therapeutic approaches in pulmonary arterial hypertension	13
Therapeutics development for Ebola virus disease: A recent scenario	13
Reactive oxygen species modulators in pulmonary medicine	13
Nutraceuticals use and type 2 diabetes mellitus	13
Celiac disease: New therapies on the horizon	12
Preclinical pharmacology modeling of chimeric antigen receptor T therapies	12
Polyphenols affect the humoral response in cancer, infectious and allergic diseases and autoimmunity by modulating the activity of TH1 and TH2 cells	12
The active kinome: The modern view of how active protein kinase networks fit in biological research	12
Breaking the barriers to remyelination in multiple sclerosis	12
Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors	12
Advances in antiobesity mechanisms of capsaicin	12
Therapeutic drug monitoring of anti-tumor necrosis factor agents: lessons learned and remaining issues	12
Microglia as therapeutic targets for central nervous system remyelination	12
Advances in tethered photopharmacology for precise optical control of signaling proteins	12
The potential role of oxytocin in addiction: What is the target process?	12
Quantitative assessment of volumetric muscle loss: Dual-energy X-ray absorptiometry and ultrasonography	12
Treatment advances in antiphospholipid syndrome: 2022 update	12
GLP-1 – Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy	11
COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”	11
Therapeutic strategies for treating juvenile idiopathic arthritis	11
Photopharmacology for vision restoration	11
Therapeutic approaches in different congenital myopathies	11
Exercise to mitigate cardiometabolic disorders after spinal cord injury	11
Caffeine consumption and schizophrenia: A highlight on adenosine receptor–independent mechanisms	11
Type 2 diabetic women are not small type 2 diabetic men: Sex-and-gender differences in antidiabetic drugs	11
Dietary serine supplementation: Friend or foe?	11
Pituitary gonadotroph-specific patterns of gene expression and hormone secretion	11
New trends in pharmacological control of neuropsychiatric symptoms of dementia	11
Circadian clocks regulate cardiac arrhythmia susceptibility, repolarization, and ion channels	11
Pancreatic alpha cells and glucagon secretion: Novel functions and targets in glucose homeostasis	11
Impaired metabolism of oligodendrocyte progenitor cells and axons in demyelinated lesion and in the aged CNS	10
Novel treatments in multidrug-resistant tuberculosis	10
The potential pharmacological mechanisms of β-hydroxybutyrate for improving cognitive functions	10
Tropical fruits from Australia as potential treatments for metabolic syndrome	10
Gastrointestinal manifestations and SARS-CoV-2 infection	10
CFTR RNA- and DNA-based therapies	10
JAK inhibitors: current position in treatment strategies for use in inflammatory bowel disease	10
Treatment of severe alcoholic hepatitis: A systematic review	10
An update on drug development for the treatment of metabolic (dysfunction) associated fatty liver disease: Progress and opportunities	10
Eosinophilic esophagitis: New molecules, better life?	10
Splice-switching as cancer therapy	10
Epigenetics in β-cell adaptation and type 2 diabetes	9
Photoswitchable allosteric modulators for metabotropic glutamate receptors	9
Opportunities and challenges for nonaddictive interventions in chronic pain	9
Repairing damaged lungs using regenerative therapy	9
Animal models of cystic fibrosis in the era of highly effective modulator therapies	9
Choosing the right drug: status and future of endocannabinoid research for the prevention of drug-seeking reinstatement	9
Neuroinflammation in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection: Pathogenesis and clinical manifestations	9
GIP(3-30)NH2 – a tool for the study of GIP physiology	9
Emerging drugs for the treatment of primary sclerosing cholangitis	9
Diabetes pharmacotherapy and circulating stem/progenitor cells. State of the art and evidence gaps	9
Mechanisms of cardio-renal protection of sodium-glucose cotransporter-2 inhibitors	9
Auxiliary subunits of the AMPA receptor: The Shisa family of proteins	9
Priming metabolism with the type 5 phosphodiesterase: the role of cGMP-hydrolyzing enzymes	9
RAD51 paralogs: Expanding roles in replication stress responses and repair	9
Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology	9
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors	9
A double-edged sword: The Kelch-like ECH-associated protein 1-nuclear factor erythroid-derived 2-related factor 2-antioxidant response element pathway targeted pharmacological modulation in nonalcohol	9
Nutrient weight against sarcopenia: regulation of the IGF-1/PI3K/Akt/FOXO pathway in quinoa metabolites	9
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?	9
Immune tolerance therapies for autoimmune diseases: Shifting the goalpost to cure	9
Current and new targets for treating myositis	8
Plant-based vaccine research development against viral diseases with emphasis on Ebola virus disease: A review study	8
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors	8
Management of blood pressure disorders in individuals with spinal cord injury	8
Current status of hepatitis delta	8

Metabolic regulation of tissue-resident memory CD8+ T cells	8
Precision medicine for rare diseases: The times they are A-Changin'	8
Store-operated calcium entry: From physiology to tubular aggregate myopathy	8
Small molecule screening as an approach to encounter inefficient myelin repair	8
Genome structure and genetic diversity in the Ebola virus	8
Towards eradication of HBV: Treatment approaches and status of clinical trials	8
Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss	8
MicroRNA: A mediator of diet-induced cardiovascular protection	8
Understanding the biology of volumetric muscle loss for an individualized exercise rehabilitation approach in breast cancer patients	8
Pharmacological strategies for mitigating anti-TNF biologic immunogenicity in rheumatoid arthritis patients	8
Novel therapeutic avenues for kisspeptin	8
Precision medicine in idiopathic pulmonary fibrosis therapy: From translational research to patient-centered care	8
Three-dimensional perspective on ryanodine receptor mutations causing skeletal and cardiac muscle-related diseases	8
Novel aspects on the role of white adipose tissue in type 2 diabetes	8
Very-low-calorie ketogenic diet: An alternative to a pharmacological approach to improve glycometabolic and gonadal profile in men with obesity	8
COVID-19 in Latin America and the caribbean region: Symptoms and morbidities in the epidemiology of infection	7
The histone code in dementia: Transcriptional and chromatin plasticity fades away	7
Treatment approach to connective tissue disease-associated interstitial lung disease	7
Targeting DNA damage repair precision medicine strategies in cancer	7
How organoids can improve personalized treatment in patients with gastro-esophageal tumors	7
A review of biosimilars for rheumatoid arthritis	7
Mucus-targeting therapies of defective mucus clearance for cystic fibrosis: A short review	7
Treatment of alcohol use disorder in patients with liver disease	7
Adipose tissue–heart crosstalk as a novel target for treatment of cardiometabolic diseases	7
Update on anti-fibrotic pharmacotherapies in skeletal muscle disease	7
Established and novel human translational models to advance cystic fibrosis research, drug discovery, and optimize CFTR-targeting therapeutics	7
Autophagy in neuronal physiology and disease	7
Functional implications of neutrophil metabolism during ischemic tissue repair	7
Anabolic–androgenic steroid abuse and testicular function in men; recent insights	7
Review: Circadian clocks and rhythms in the vascular tree	7
Adipocyte purinergic receptors activated by uracil nucleotides as obesity and type 2 diabetes targets	7
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?	7
Targeting TRP channels for pain relief: A review of current evidence from bench to bedside	6
Imaging biomarkers for Alzheimer’s disease and glaucoma: Current and future practices	6
Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies	6
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity	6
Nonsteroidal mineralcorticoid receptor antagonists: Novel therapeutic implication in the management of patients with type 2 diabetes	6
Tapering biologic DMARDs in rheumatoid arthritis	6
Systems modeling of metabolic dysregulation in neurodegenerative diseases	6
Targeting ferroptosis in the maintenance of mitochondrial homeostasis in the realm of septic cardiomyopathy	6
Low FODMAP diet beyond IBS: Evidence for use in other conditions	6
Purinergic signalling in graft-versus-host disease	6
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	6
Impacts of the Filoviridae family	6
Circadian variations of vasoconstriction and blood pressure in physiology and diabetes	6
Current and emerging biologic and small molecule systemic treatment options for psoriasis and psoriatic arthritis	6
Fluorescent chemigenetic actuators and indicators for use in living animals	6
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway	6
Circulating factors that influence the central nervous system remyelination	6