Current Opinion in Pharmacology

Papers
(The median citation count of Current Opinion in Pharmacology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-01-01 to 2025-01-01.)
ArticleCitations
Recent advances in emerging PCOS therapies64
Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology63
Interrogating the function of GABAA receptors in the brain with optogenetic pharmacology59
Novel strategies to promote resolution of inflammation to treat lower extremity artery disease54
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies48
Editorial overview: Immune regulation and cancers47
Editorial Board45
Established and novel human translational models to advance cystic fibrosis research, drug discovery, and optimize CFTR-targeting therapeutics42
Routine neoadjuvant chemotherapy for all patients with resectable pancreatic ductal adenocarcinoma? A review of the evidence41
Editorial overview – 2022 respiratory issue: Cystic fibrosis pathophysiology, models, and novel therapies40
Impact of amino acids on microglial activation and CNS remyelination37
The role of extracellular ATP in homeostatic immune cell migration35
Editorial Board32
Lipid raft disruption as an opportunity for peripheral analgesia32
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration31
Editorial Board31
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”30
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development29
Host membrane proteins in the HIV-induced membrane fusion: Role in pathogenesis and therapeutic potential of autoantibodies29
Editorial Board28
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer27
Quantitative assessment of volumetric muscle loss: Dual-energy X-ray absorptiometry and ultrasonography26
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling25
Drug effects on neuropeptides and their receptors: Big hopes but moderate success in the treatment of chronic pain25
Non-alcoholic fatty liver disease: Current therapeutic options25
MicroRNA: A mediator of diet-induced cardiovascular protection25
Dietary serine supplementation: Friend or foe?24
Beyond the AMPA receptor: Diverse roles of SynDIG/PRRT brain-specific transmembrane proteins at excitatory synapses24
Splice-switching as cancer therapy23
Nutraceuticals in mental diseases — Bridging the gap between traditional use and modern pharmacology23
The 2013–2016 Ebola virus disease outbreak in West Africa23
Stress, kisspeptin, and functional hypothalamic amenorrhea22
Nutraceuticals use and type 2 diabetes mellitus22
New CARs on and off the road: challenges and new developments in CAR-T cell therapy21
Current pharmacological treatment of hepatocellular carcinoma21
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers21
Emerging drugs for the treatment of primary sclerosing cholangitis21
Circulating factors that influence the central nervous system remyelination21
Metabolic regulation of tissue-resident memory CD8+ T cells21
Pharmacologic treatment of gastroparesis: What is (still) on the horizon?20
Photopharmacological control of cell signaling with photoswitchable lipids20
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?19
Targeting the soluble epoxide hydrolase pathway as a novel therapeutic approach for the treatment of pain18
Elexacaftor–tezacaftor–ivacaftor: The new paradigm to treat people with cystic fibrosis with at least one p.Phe508del mutation17
Integrating network pharmacology: The next-generation approach in ocular drug discovery17
Hormonal drugs for the treatment of endometriosis17
Gestational diabetes: Implications for fetal growth, intervention timing, and treatment options17
N-methyl-d-aspartate receptor function in neuronal and synaptic development and signaling17
The active kinome: The modern view of how active protein kinase networks fit in biological research17
Photoswitchable allosteric modulators for metabotropic glutamate receptors17
How organoids can improve personalized treatment in patients with gastro-esophageal tumors17
Prospects for COPD treatment17
The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: A mini-review of the potential mechanisms17
Tropical fruits from Australia as potential treatments for metabolic syndrome17
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe17
Corrigendum to ‘JAK inhibitors: Current position in treatment strategies for use in inflammatory bowel disease’17
Chronotherapy of cardiac and vascular disease: timing medications to circadian rhythms to optimize treatment effects and outcomes16
Disease-modifying therapies in short bowel syndrome16
Corticosteroids and circadian rhythms in the cardiovascular system16
New developments in treatments for systemic vasculitis16
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway16
Adenosine signaling as target in cardiovascular pharmacology16
Targeting the altered duodenal microenvironment in functional dyspepsia15
Targeting fibroblast-like synoviocytes in rheumatoid arthritis15
Remyelinating strategies: What can be learned from normal brain development15
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma15
Editorial Board15
Polyphenols affect the humoral response in cancer, infectious and allergic diseases and autoimmunity by modulating the activity of TH1 and TH2 cells15
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder14
Editorial overview: Endocrine and metabolic diseases (2023)14
Gastrointestinal issue: Advances in gastrointestinal oncology14
Cancer 2021: New therapeutic approaches for the treatment of cancer — building on advances in cancer biology and the molecular genetics of cancer14
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation14
Editorial Board14
A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease14
Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases13
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?13
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction13
Nonsteroidal mineralcorticoid receptor antagonists: Novel therapeutic implication in the management of patients with type 2 diabetes13
Editorial Board13
From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches13
Optofluidic neural interfaces for in vivo photopharmacology13
Recent developments and strategies of Ebola virus vaccines13
Practical application of breath tests in disorders of gut–brain interaction13
Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?13
Artemisinins and their impact on inhibitory neurotransmission13
Editorial overview: Neuroscience: Advances in the field13
Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss13
The complement pathway as a therapeutic target for neovascular age-related macular degeneration-mediated subretinal fibrosis13
The hypodopaminergic state ten years after: transcranial magnetic stimulation as a tool to test the dopamine hypothesis of drug addiction12
Current status of hepatitis delta12
Photo-isomerizable tweezers to probe ionotropic receptor mechanisms12
Hepatic arterial infusion chemotherapy for patients with hepatocellular carcinoma: Applicability in Western countries12
Applications of chemogenetics in non-human primates12
Targeting drug memory reconsolidation: a neural analysis12
Purinergic signalling in graft-versus-host disease12
Astrocytes as cellular mediators of cue reactivity in addiction12
Optic nerve regeneration: Potential treatment approaches12
Type 2 diabetic women are not small type 2 diabetic men: Sex-and-gender differences in antidiabetic drugs12
The potential pharmacological mechanisms of β-hydroxybutyrate for improving cognitive functions12
Adoptive cell therapy for solid tumors: Chimeric antigen receptor T cells and beyond11
The potential role of oxytocin in addiction: What is the target process?11
Therapeutic strategies for treating juvenile idiopathic arthritis11
Role of HSV-1 in Alzheimer's disease pathogenesis: A challenge for novel preventive/therapeutic strategies11
Analgesic potential of voltage gated sodium channel modulators for the management of pain11
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity11
Light-activated receptor tyrosine kinases: Designs and applications11
The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids11
Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder11
RAD51 paralogs: Expanding roles in replication stress responses and repair11
Genetic risk scores and personalization of care in fatty liver disease11
Pancreatic alpha cells and glucagon secretion: Novel functions and targets in glucose homeostasis11
Editorial overview: Special issue on “Rheumatology: Therapeutic advances for autoimmune and musculoskeletal diseases”10
Neuroinflammation in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection: Pathogenesis and clinical manifestations10
Therapeutic innovations for geographic atrophy: A promising horizon10
Immune tolerance therapies for autoimmune diseases: Shifting the goalpost to cure10
Photopharmacology for vision restoration10
Advances in lupus therapeutics: Achieving sustained control of the type I interferon pathway10
Pharmacologic approaches to prevent skeletal muscle atrophy after spinal cord injury10
Corrigendum to “Metformin: Still the sweet spot for CV protection in diabetes?” [Curr Opin Pharmacol 54 (2020) 202–208]10
Effects of protein glycation and protective mechanisms against glycative stress10
Three-dimensional perspective on ryanodine receptor mutations causing skeletal and cardiac muscle-related diseases10
Biased signalling in analgesic research and development9
The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy9
Advances in antiobesity mechanisms of capsaicin9
Choosing the right drug: status and future of endocannabinoid research for the prevention of drug-seeking reinstatement9
Fluorescent chemigenetic actuators and indicators for use in living animals9
Three-dimensional culture models to study glioblastoma — current trends and future perspectives9
Nanotechnology in pulmonary medicine9
Priming metabolism with the type 5 phosphodiesterase: the role of cGMP-hydrolyzing enzymes9
Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance9
Editorial Board9
Towards eradication of HBV: Treatment approaches and status of clinical trials9
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis9
Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration9
Management of blood pressure disorders in individuals with spinal cord injury9
Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications9
Circadian influence on inflammatory response during cardiovascular disease9
Dementia therapeutics and cognitive rehabilitation8
Immune dysfunction after spinal cord injury – A review of autonomic and neuroendocrine mechanisms8
Reviewing the toolbox for degrader development in oncology8
Eosinophilic esophagitis: New molecules, better life?8
The role of Pannexin-1 channels, ATP, and purinergic receptors in the pathogenesis of HIV and SARS-CoV-28
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle8
Editorial overview: Introduction to the musculoskeletal section of current opinion in pharmacology8
Editorial Board8
Editorial Board8
MedXercise: a promising strategy to promote remyelination8
Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease8
Targeting the endocannabinoid system for the management of low back pain8
Publisher’s Note8
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?8
The expanding role of split protein complementation in opsin-free optogenetics8
Cardiac circadian rhythms in time and space: The future is in 4D8
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?8
AI-driven GPCR analysis, engineering, and targeting8
Publisher Note - Virtual Special Issue8
Low FODMAP diet beyond IBS: Evidence for use in other conditions8
The role of extracellular ATP and P2X receptors in the pathogenesis of HIV-17
Precision medicine in idiopathic pulmonary fibrosis therapy: From translational research to patient-centered care7
Drug repurposing in skeletal muscle ion channelopathies7
Environmental enrichment-inspired pharmacological tools for the treatment of addiction7
KRAS inhibition in metastatic colorectal cancer: An update7
Novel treatments for dry eye syndrome7
Purinergic signaling pathway in severe COVID-197
Preclinical pharmacology modeling of chimeric antigen receptor T therapies7
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus7
Novel treatments in multidrug-resistant tuberculosis7
Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies7
Treatments targeting the luminal gut microbiota in patients with irritable bowel syndrome7
Update on anti-fibrotic pharmacotherapies in skeletal muscle disease7
The use of hormone stimulation in male infertility7
NMR applications to GPCR recognition by peptide ligands7
A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury7
CFTR RNA- and DNA-based therapies7
Modulating regulatory T cell migration in the treatment of autoimmunity and autoinflammation7
Genome structure and genetic diversity in the Ebola virus7
Optical control of Class A G protein-coupled receptors with photoswitchable ligands6
Treatment of early rheumatoid arthritis: Methotrexate and beyond6
Exercise as a drug for glucose management and prevention in type 2 diabetes mellitus6
Animal models of cystic fibrosis in the era of highly effective modulator therapies6
Lynx1 prototoxins: critical accessory proteins of neuronal nicotinic acetylcholine receptors6
COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”6
Advances in tethered photopharmacology for precise optical control of signaling proteins6
Gastrointestinal manifestations and SARS-CoV-2 infection6
Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming6
Corrigendum to “Antihypertensive effect of soybean bioactive peptides: A review” [Curr Opin Pharmacol (62) (2022) 74–81]6
Role of specific CDKs in regulating DNA damage repair responses and replication stress6
Pharmacology of pannexin channels6
Targeting KNDy neurons to control GnRH pulses6
The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases6
Caffeine consumption and schizophrenia: A highlight on adenosine receptor–independent mechanisms6
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