BMC Medical Research Methodology

Article	Citations
The Preventiometer - reliability of a cardiovascular multi-device measurement platform and its measurement agreement with a cohort study	338
Psychometric validation techniques applied to the IND-VFQ-33 visual function questionnaire: the Hyderabad ocular morbidity in the elderly study (HOMES)	310
Assessment of the E-value in the presence of bias amplification: a simulation study	305
Understanding facilitators of research participation among adults with self-reported chronic pain – a survey examining hypothetical research participation	218
Regression models for interval censored data using parametric pseudo-observations	165
Tailored approach to participant recruitment and retention to maximize health equity in pediatric cancer research	136
Adjusting for outcome risk factors in immigrant datasets: total or direct effects?	135
Development of a diagnostic predictive model for determining child stunting in Malawi: a comparative analysis of variable selection approaches	111
Dynamic prediction based on variability of a longitudinal biomarker	94
Clinical systematic reviews – a brief overview	92
Which test for crossing survival curves? A user’s guideline	88
Outbreaks of publications about emerging infectious diseases: the case of SARS-CoV-2 and Zika virus	77
A data-driven pipeline to extract potential adverse drug reactions through prescription, procedures and medical diagnoses analysis: application to a cohort study of 2,010 patients taking hydroxychloro	75
crossnma: An R package to synthesize cross-design evidence and cross-format data using network meta-analysis and network meta-regression	69
Prognostic score-based model averaging approach for propensity score estimation	68
Do authors of systematic reviews of epidemiological observational studies assess the methodologies of the included primary studies? An empirical examination of methodological tool use in the literatur	67
Immortal time bias for life-long conditions in retrospective observational studies using electronic health records	64
Spatial data analysis of malnutrition among children under-five years in Ethiopia	64
Informed Bayesian survival analysis	60
Impact of different unconditional monetary incentives on survey response rates in men with prostate cancer: a 2-arm randomised trial	58
A clinical phase I dose-finding design with adaptive shrinking boundaries for drug combination trials	57
Using electronic health records to inform trial feasibility in a rare autoimmune blistering skin disease in England	57
Dementia risk prediction in individuals with mild cognitive impairment: a comparison of Cox regression and machine learning models	53
An ego-centred approach for the evaluation of spatial effects on health in urban areas based on parametric semi-variogram models: concept and validation	50
Better performance for right-skewed data using an alternative gamma model	48

Investigating factors affecting the interval between a burn and the start of treatment using data mining methods and logistic regression	45
An improved method for the effect estimation of the intermediate event on the outcome based on the susceptible pre-identification	44
Clinical research activities during COVID-19: the point of view of a promoter of academic clinical trials	41
BivRec: an R package for the nonparametric and semiparametric analysis of bivariate alternating recurrent events	41
Comparison of statistical methods for the analysis of recurrent adverse events in the presence of non-proportional hazards and unobserved heterogeneity: a simulation study	41
Methodological identification of anomalies episodes in ECG streams: a systematic mapping study	40
Interactive molecular causal networks of hypertension using a fast machine learning algorithm MRdualPC	40
Use of systems thinking and adapted group model building methods to understand patterns of technology use among older adults with type 1 diabetes: a preliminary process evaluation	39
Ripple effects mapping: capturing the wider impacts of systems change efforts in public health	39
Detecting the patient’s need for help with machine learning based on expressions	38
A new infodemiological approach through Google Trends: longitudinal analysis of COVID-19 scientific and infodemic names in Italy	38
An investigation of the constancy of effect in Cochrane systematic reviews in context with the assumptions for noninferiority trials	36
Classification of PR-positive and PR-negative subtypes in ER-positive and HER2-negative breast cancers based on pathway scores	35
Neutral theory: applicability and neutrality of using generic health-related quality of life tools in diseases or conditions where specific tools are available	35
Methodological assessment of systematic reviews of in-vitro dental studies	34
Interchangeability and optimization of heart rate methods for estimating oxygen uptake in ergometer cycling, level treadmill walking and running	33
CalScope: methodology and lessons learned for conducting a remote statewide SARS-CoV-2 seroprevalence study in California using an at-home dried blood spot collection kit and online survey	32
Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis	32
Comparison of reference distributions acquired by direct and indirect sampling techniques: exemplified with the Pediatric Reference Interval in China (PRINCE) study	32
Reporting and communication of sample size calculations in adaptive clinical trials: a review of trial protocols and grant applications	31
Implementing multiple imputations for addressing missing data in multireader multicase design studies	31
A framework to model global, regional, and national estimates of intimate partner violence	31
Modeling heart rate of individual and team manual handling with one hand using generalized additive mixed models	30
Group sequential designs for pragmatic clinical trials with early outcomes: methods and guidance for planning and implementation	29
Evaluation of multiple imputation approaches for handling missing covariate information in a case-cohort study with a binary outcome	29
Ensuring cross-cultural data comparability by means of anchoring vignettes in heterogeneous refugee samples	28
Comparing outcomes from tailored meta-analysis with outcomes from a setting specific test accuracy study using routine data of faecal calprotectin testing for inflammatory bowel disease	28
Pre-statistical harmonization of behavioral instruments across eight surveys and trials	28
Recruitment methods and yield rates in a clinical trial of physical exercise for older adults with hypertension—HAEL Study: a study within a trial	28
Joint analysis of PK and immunogenicity outcomes using factorization model − a powerful approach for PK similarity study	27
Addressing misclassification bias in vaccine effectiveness studies with an application to Covid-19	27
Interdisciplinary sport injury research and the integration of qualitative and quantitative data	27
A gated group sequential design for seamless Phase II/III trial with subpopulation selection	26
Should RECOVERY have used response adaptive randomisation? Evidence from a simulation study	25
Modular literature review: a novel systematic search and review method to support priority setting in health policy and practice	25
Promoting data harmonization to evaluate vaccine hesitancy in LMICs: approach and applications	25
A compartmental model for smoking dynamics in Italy: a pipeline for inference, validation, and forecasting under hypothetical scenarios	25
Functional data analysis to characterize disease patterns in frequent longitudinal data: application to bacterial vaginal microbiota patterns using weekly Nugent scores and identification of pattern-s	24
Longitudinal mediation analysis with multilevel and latent growth models: a separable effects causal approach	24
Safety analysis of new medications in clinical trials: a simulation study to assess the differences between cause-specific and subdistribution frameworks in the presence of competing events	24
Data quality in an HIV vaccine efficacy clinical trial in South Africa: through natural disasters and with discipline	24
Tracking modifications to implementation strategies: a case study from SNaP - a hybrid type III randomized controlled trial to scale up integrated systems navigation and psychosocial counseling for PW	24
Evaluation of Bayesian spatiotemporal infectious disease models for prospective surveillance analysis	23
A spatial obesity risk score for describing the obesogenic environment using kernel density estimation: development and parameter variation	22
The iterative bisection procedure: a useful tool for determining parameter values in data-generating processes in Monte Carlo simulations	22
MetaAnalyst: a user-friendly tool for metagenomic biomarker detection and phenotype classification	22
Adaptations for remote research work: a modified web-push strategy compared to a mail-only strategy for administering a survey of healthcare experiences	22
Should multiple imputation be stratified by exposure group when estimating causal effects via outcome regression in observational studies?	22
Mind the gap: covariate constrained randomisation can protect against substantial power loss in parallel cluster randomised trials	21
A Bayesian network perspective on neonatal pneumonia in pregnant women with diabetes mellitus	21

Simulation analysis of an adjusted gravity model for hospital admissions robust to incomplete data	21
Application of the multiple dependent state sampling strategy to late adolescent suicide rates	21
How well did the consensus methods apply in the guideline development of traditional Chinese medicine: a web-based survey in China	20
Construction of the Armenian Surname List (ASL) for public health research	20
Raking of data from a large Australian cohort study improves generalisability of estimates of prevalence of health and behaviour characteristics and cancer incidence	20
IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy	20
Interpretable generalized neural additive models for mortality prediction of COVID-19 hospitalized patients in Hamadan, Iran	19
Identification of difficult laryngoscopy using an optimized hybrid architecture	19
Sex-specific analysis of traumatic brain injury events: applying computational and data visualization techniques to inform prevention and management	19
regCOVID: Tracking publications of registered COVID-19 studies	19
The INSPIRE Population Survey: development, dissemination and respondent characteristics	19
Patient regional index: a new way to rank clinical specialties based on outpatient clinics big data	19
Correction of vaccine effectiveness derived from test-negative case–control studies	18
Evaluation of the Fill-it-up-design to use historical control data in randomized clinical trials with two arm parallel group design	18
Reasons for missing evidence in rehabilitation meta-analyses: a cross-sectional meta-research study	18
Standard of care for COVID-19 in randomized clinical trials registered in trial registries and published in preprint servers and scholarly journals: a cross-sectional study	18
Comparing statistical methods in assessing the prognostic effect of biomarker variability on time-to-event clinical outcomes	18
Adaptive designs in critical care trials: a simulation study	18
Major mistakes or errors in the use of trial sequential analysis in systematic reviews or meta-analyses – the METSA systematic review	18
Gaps in the usage and reporting of multiple imputation for incomplete data: findings from a scoping review of observational studies addressing causal questions	17
Accelerating evidence synthesis for safety assessment through ClinicalTrials.gov platform: a feasibility study	17
Designing tailored maintenance strategies for systematic reviews and clinical practice guidelines using the Portfolio Maintenance by Test-Treatment (POMBYTT) framework	17
Combining propensity score methods with variational autoencoders for generating synthetic data in presence of latent sub-groups	17
Multiple imputation to quantify misclassification in observational studies of the cognitively impaired: an application for pain assessment in nursing home residents	17
Responsiveness of different pain measures and recall periods in people undergoing surgery after a period of splinting for basal thumb joint osteoarthritis	16
Constructing within and between hospital physician social networks for modeling physician research participation	16
The endorsement of general and artificial intelligence reporting guidelines in radiological journals: a meta-research study	16
Neutral theory: applicability and neutrality of clinical study endpoints where a disease-specific instrument is available	16
Comparison between asymptotic and re-randomisation tests under non-proportional hazards in a randomised controlled trial using the minimisation method	16
Frequency-based rare diagnoses as a novel and accessible approach for studying rare diseases in large datasets: a cross-sectional study	16
The reporting of prognostic prediction models for obstetric care was poor: a cross-sectional survey of 10-year publications	16
Does imbalance in chest X-ray datasets produce biased deep learning approaches for COVID-19 screening?	15
Predicting the presence of depressive symptoms in the HIV-HCV co-infected population in Canada using supervised machine learning	15
Telephone peer recruitment and interviewing during a respondent-driven sampling (RDS) survey: feasibility and field experience from the first phone-based RDS survey among men who have sex with men in	15
Central data monitoring in the multicentre randomised SafeBoosC-III trial – a pragmatic approach	15
Modelling of intensive care unit (ICU) length of stay as a quality measure: a problematic exercise	15
External validation of the American prediction model for incident type 2 diabetes in the Iranian population	15
coreSCD: multi-stakeholder consensus on core outcomes for sickle cell disease clinical trials	15
Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia	15
Developing survey weights to ensure representativeness in a national, matched cohort study: results from the children and young people with Long Covid (CLoCk) study	14
The validity, reliability and feasibility of four instruments for assessing the consciousness of stroke patients in a neurological intensive care unit compared	14
Are morbidity and mortality estimates from randomized controlled trials externally valid? A comparison of outcomes among infants enrolled into an RCT or a cohort study in Botswana	14
Time and change: a typology for presenting research findings in qualitative longitudinal research	14
Contextual effects: how to, and how not to, quantify them	14
The impact of iterative removal of low-information cluster-period cells from a stepped wedge design	14
Growth mixture models: a case example of the longitudinal analysis of patient‐reported outcomes data captured by a clinical registry	14
Guidelines are needed for studies of pre-treatment HIV drug resistance: a methodological study	14
Informing the research agenda for optimizing audit and feedback interventions: results of a prioritization exercise	14
Bayesian mendelian randomization with study heterogeneity and data partitioning for large studies	14
Cluster randomised trials with a binary outcome and a small number of clusters: comparison of individual and cluster level analysis method	14
Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach?	14
Reporting of interventional clinical trial results in an academic center: a survey of completed studies	14
CRIME-Q—a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research	13
Addressing treatment switching in the ALTA-1L trial with g-methods: exploring the impact of model specification	13
Effects of missing data imputation methods on univariate blood pressure time series data analysis and forecasting with ARIMA and LSTM	13
Grouped data with survey revision	13
The analysis and reporting of multiple outcomes in mental health trials: a methodological systematic review	13
Toward value-based care using cost mining: cost aggregation and visualization across the entire colorectal cancer patient pathway	13
Recruitment into antibody prevalence studies: a randomized trial of postcards vs. letters as invitations	13
Using a distribution-based approach and systematic review methods to derive minimum clinically important differences	13
Effects of different invitation strategies on participation in a cohort study of Iranian public sector employees: a cluster randomized trial	13
Robustness assessment of regressions using cluster analysis typologies: a bootstrap procedure with application in state sequence analysis	13
The use of sequential multiple assignment randomized trials (SMARTs) in physical activity interventions: a systematic review	13
Estimation of marginal structural models under irregular visits and unmeasured confounder: calibrated inverse probability weights	13
Fast and optimal algorithm for case-control matching using registry data: application on the antibiotics use of colorectal cancer patients	12
Research monitoring practices in critical care research: a survey of current state and attitudes	12
Choices of measures of association affect the visualisation and composition of the multimorbidity networks	12
Risk prediction in multicentre studies when there is confounding by cluster or informative cluster size	12
Ordinal outcome analysis improves the detection of between-hospital differences in outcome	12
Methodological aspects for accelerometer-based assessment of physical activity in heart failure and health	12
External validation of existing dementia prediction models on observational health data	12
A comparison of statistical methods for modeling count data with an application to hospital length of stay	12
Systematic review and meta analysis of differential attrition between active and control arms in randomized controlled trials of lifestyle interventions in chronic disease	12
Estimating restricted mean survival time and expected life-years lost in the presence of competing risks within flexible parametric survival models	12
An evaluation of computational methods for aggregate data meta-analyses of diagnostic test accuracy studies	12
Systematic reviews and meta-analysis published in indexed Portuguese medical journals: time trends and critical appraisal	12
Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods	12
Sample size requirements are not being considered in studies developing prediction models for binary outcomes: a systematic review	12
Test–retest reliability of selected HBSC items in Vietnam: well-being, physical and sedentary activities, and eating behaviours	12
Predicting lung cancer survival prognosis based on the conditional survival bayesian network	11

unmconf : an R package for Bayesian regression with unmeasured confounders	11
Evaluating the current methodological practices and issues in existing literature in pooling complex surveys: a systematic review	11
Similarities, reliability and gaps in assessing the quality of conduct of systematic reviews using AMSTAR-2 and ROBIS: systematic survey of nutrition reviews	11
Making implementation science more real	11
Motivations for enrollment in a COVID-19 ring-based post-exposure prophylaxis trial: qualitative examination of participant experiences	11
Towards realist-informed ripple effects mapping (RREM): positioning the approach	11
Weighted metrics are required when evaluating the performance of prediction models in nested case–control studies	11
Flexible Bayesian semiparametric mixed-effects model for skewed longitudinal data	11
Satisfaction and experience with colorectal cancer screening: a systematic review of validated patient reported outcome measures	11
Multistate Markov chain modeling for child undernutrition transitions in Ethiopia: a longitudinal data analysis, 2002–2016	11
Two-step spatiotemporal anomaly detection corrected for lag reporting time with application to real-time dengue surveillance in Thailand	11
Predictive P-score for treatment ranking in Bayesian network meta-analysis	11
geessbin: an R package for analyzing small-sample binary data using modified generalized estimating equations with bias-adjusted covariance estimators	11
The optimal approach for retrieving systematic reviews was achieved when searching MEDLINE and Epistemonikos in addition to reference checking: a methodological validation study	11
The effect of home visits as an additional recruitment step on the composition of the final sample: a cross-sectional analysis in two study centers of the German National Cohort (NAKO)	11
Bayesian Mendelian randomization with an interval causal null hypothesis: ternary decision rules and loss function calibration	11
Application of the estimand framework for an emulated trial using reference based multiple imputation to investigate informative censoring	10
External control arm analysis: an evaluation of propensity score approaches, G-computation, and doubly debiased machine learning	10
What do stroke survivors’ value about participating in research and what are the most important research problems related to stroke or transient ischemic attack (TIA)? A survey	10
Inference following multiple imputation for generalized additive models: an investigation of the median p-value rule with applications to the Pulmonary Hypertension Association Registry and Colorado C	10
Quality appraisal for systematic literature reviews of health state utility values: a descriptive analysis	10
Analyzing missingness patterns in real-world data using the SMDI toolkit: application to a linked EHR-claims pharmacoepidemiology study	10
Multiple imputation using auxiliary imputation variables that only predict missingness can increase bias due to data missing not at random	10
From simple to even simpler, but not too simple: a head-to-head comparison of the Better-Worse and Drop-Down methods for measuring patient health status	10
Modelling wound area in studies of wound healing interventions	10
Machine learning in medicine: a practical introduction to natural language processing	10
Power and sample size calculation for incremental net benefit in cost effectiveness analyses with applications to trials conducted by the Canadian Cancer Trials Group	10
The methodological quality assessment of systematic reviews/meta-analyses of chronic prostatitis/chronic pelvic pain syndrome using AMSTAR2	10
Prediction of congenital heart disease for newborns: comparative analysis of Holt-Winters exponential smoothing and autoregressive integrated moving average models	10
Comparing current and emerging practice models for the extrapolation of survival data: a simulation study and case-study	10
COVID-19-related medical research: a meta-research and critical appraisal	10
Forecasting COVID-19 cases using time series modeling and association rule mining	10
Minimal important difference, patient acceptable symptom state and longitudinal validity of oxford elbow score and the quickDASH in patients with tennis elbow	10
Concordance rate of a four-quadrant plot for repeated measurements	10
Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods	10
The impact of different censoring methods for analyzing survival using real-world data with linked mortality information: a simulation study	10
Inverse probability weighting to handle attrition in cohort studies: some guidance and a call for caution	10
Use and misuse of random forest variable importance metrics in medicine: demonstrations through incident stroke prediction	9
More than one third of clinical practice guidelines on low back pain overlap in AGREE II appraisals. Research wasted?	9
Classifying information-sharing methods	9
Correction: In health research publications, the number of authors is strongly associated with collective self-citations but less so with citations by others	9
Correction: Real‑world data: a brief review of the methods, applications, challenges and opportunities	9
Restrictions and their reporting in systematic reviews of effectiveness: an observational study	9
Design and analysis of outcomes following SARS-CoV-2 infection in veterans	9
A simple pooling method for variable selection in multiply imputed datasets outperformed complex methods	9
Open science saves lives: lessons from the COVID-19 pandemic	9
Outbreak detection algorithms based on generalized linear model: a review with new practical examples	9
Correction: Analysis of zero inflated dichotomous variables from a Bayesian perspective: application to occupational health	9
Causal effect of chemotherapy received dose intensity on survival outcome: a retrospective study in osteosarcoma	9
Three new methodologies for calculating the effective sample size when performing population adjustment	9
Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study	9
Relationship between patient experience and hospital readmission: system-level survey with deterministic data linkage method	9
Application of machine learning in predicting hospital readmissions: a scoping review of the literature	9
Technologies for frailty, comorbidity, and multimorbidity in older adults: a systematic review of research designs	9
Correction: Accounting for expected attrition in the planning of cluster randomized trials for assessing treatment effect heterogeneity	9
Evaluating complex interventions in context: systematic, meta-narrative review of case study approaches	9
The role of the estimand framework in the analysis of patient-reported outcomes in single-arm trials: a case study in oncology	9
Comparison of prevalence and exposure-disease associations using self-report and hospitalization data among enrollees of the world trade center health registry	8
Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART	8
Empirical assessment of alternative methods for identifying seasonality in observational healthcare data	8
Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer	8
Applying a novel approach to scoping review incorporating artificial intelligence: mapping the natural history of gonorrhoea	8
Stability analysis and numerical evaluations of a COVID-19 model with vaccination	8
Internal validation of self-reported case numbers in hospital quality reports: preparing secondary data for health services research	8
Pharmacokinetic parameter driven outcomes model predicts a reduction in bleeding events associated with BAY 81–8973 versus antihemophilic factor (recombinant) plasma/albumin-free method in a Chinese h	8
Improving retention of community-recruited participants in HIV prevention research through Saturday household visits; findings from the HPTN 071 (PopART) study in South Africa	8
Estimating age-specific COVID-19 fatality risk and time to death by comparing population diagnosis and death patterns: Australian data	8
Segmentation of patients with small cell lung cancer into responders and non-responders using the optimal cross-validation technique	8
FOUNTAIN: a modular research platform for integrated real-world evidence generation	8
Comparative age-period-cohort analysis	8
How to specify healthcare process improvements collaboratively using rapid, remote consensus-building: a framework and a case study of its application	8
Correction to: A tutorial on pilot studies: the what, why and how	8
Revisiting methods for modeling longitudinal and survival data: Framingham Heart Study	8
Two-stage sampling in the estimation of growth parameters and percentile norms: sample weights versus auxiliary variable estimation	8
Comparing regression modeling strategies for predicting hometime	8
Shifting research culture to address the mismatch between where trials recruit and where populations with the most disease live: a qualitative study	8
A meta-review demonstrates improved reporting quality of qualitative reviews following the publication of COREQ- and ENTREQ-checklists, regardless of modest uptake	8
Correction: Multi‑arm multi‑stage (MAMS) randomised selection designs: impact of treatment selection rules on the operating characteristics	8
A scoping review of statistical methods in studies of biomarker-related treatment heterogeneity for breast cancer	8
Strategies for assessing the impact of loss to follow-up on estimates of neurodevelopmental impairment in a very preterm cohort at 2 years of age	8
Bayesian Hodges-Lehmann tests for statistical equivalence in the two-sample setting: Power analysis, type I error rates and equivalence boundary selection in biomedical research	8
Confounding-adjustment methods for the causal difference in medians	8
Capturing the variety of clinical pathways in patients with schizophrenic disorders through state sequences analysis	7
The effect of high prevalence of missing data on estimation of the coefficients of a logistic regression model when using multiple imputation	7
Estimation of treatment effects in observational stroke care data: comparison of statistical approaches	7
Predicting health outcomes with intensive longitudinal data collected by mobile health devices: a functional principal component regression approach	7
Competing-risks analysis for evaluating the prognosis of patients with microinvasive cutaneous squamous cell carcinoma based on the SEER database	7
A Bayesian analysis integrating expert beliefs to better understand how new evidence ought to update what we believe: a use case of chiropractic care and acute lumbar disc herniation with early surger	7
Model-based standardization using multiple imputation	7
Minimizing sample bias due to stigmatized behaviours: the representativeness of participants in a cohort study of alcohol in pregnancy	7
Frameworks for estimating causal effects in observational settings: comparing confounder adjustment and instrumental variables	7
Functional principal component analysis and sparse-group LASSO to identify associations between biomarker trajectories and mortality among hospitalized SARS-CoV-2 infected individuals	7
Bayesian modeling of spatially differentiated multivariate enamel defects of the children’s primary maxillary central incisor teeth	7
Balancing between reality, ideality, and equity: critical reflections from recruiting key informants for qualitative health research	7
Spatial-temporal Bayesian accelerated failure time models for survival endpoints with applications to prostate cancer registry data	7