BMC Medical Research Methodology

Article	Citations
The Preventiometer - reliability of a cardiovascular multi-device measurement platform and its measurement agreement with a cohort study	338
Psychometric validation techniques applied to the IND-VFQ-33 visual function questionnaire: the Hyderabad ocular morbidity in the elderly study (HOMES)	310
Assessment of the E-value in the presence of bias amplification: a simulation study	305
Understanding facilitators of research participation among adults with self-reported chronic pain – a survey examining hypothetical research participation	218
Regression models for interval censored data using parametric pseudo-observations	165
Tailored approach to participant recruitment and retention to maximize health equity in pediatric cancer research	136
Adjusting for outcome risk factors in immigrant datasets: total or direct effects?	135
Development of a diagnostic predictive model for determining child stunting in Malawi: a comparative analysis of variable selection approaches	94
Dynamic prediction based on variability of a longitudinal biomarker	92
The proper application of logistic regression model in complex survey data: a systematic review	88
Clinical systematic reviews – a brief overview	77
Which test for crossing survival curves? A user’s guideline	75
Outbreaks of publications about emerging infectious diseases: the case of SARS-CoV-2 and Zika virus	69
A data-driven pipeline to extract potential adverse drug reactions through prescription, procedures and medical diagnoses analysis: application to a cohort study of 2,010 patients taking hydroxychloro	68
crossnma: An R package to synthesize cross-design evidence and cross-format data using network meta-analysis and network meta-regression	67
Do authors of systematic reviews of epidemiological observational studies assess the methodologies of the included primary studies? An empirical examination of methodological tool use in the literatur	64
Prognostic score-based model averaging approach for propensity score estimation	64
Immortal time bias for life-long conditions in retrospective observational studies using electronic health records	60
Spatial data analysis of malnutrition among children under-five years in Ethiopia	58
Impact of different unconditional monetary incentives on survey response rates in men with prostate cancer: a 2-arm randomised trial	57
Informed Bayesian survival analysis	57
Using electronic health records to inform trial feasibility in a rare autoimmune blistering skin disease in England	53
A clinical phase I dose-finding design with adaptive shrinking boundaries for drug combination trials	50
Dementia risk prediction in individuals with mild cognitive impairment: a comparison of Cox regression and machine learning models	48
An ego-centred approach for the evaluation of spatial effects on health in urban areas based on parametric semi-variogram models: concept and validation	45

Better performance for right-skewed data using an alternative gamma model	44
BivRec: an R package for the nonparametric and semiparametric analysis of bivariate alternating recurrent events	41
An improved method for the effect estimation of the intermediate event on the outcome based on the susceptible pre-identification	41
Investigating factors affecting the interval between a burn and the start of treatment using data mining methods and logistic regression	41
Clinical research activities during COVID-19: the point of view of a promoter of academic clinical trials	40
Comparison of statistical methods for the analysis of recurrent adverse events in the presence of non-proportional hazards and unobserved heterogeneity: a simulation study	40
Methodological identification of anomalies episodes in ECG streams: a systematic mapping study	39
Ripple effects mapping: capturing the wider impacts of systems change efforts in public health	38
Interactive molecular causal networks of hypertension using a fast machine learning algorithm MRdualPC	38
Use of systems thinking and adapted group model building methods to understand patterns of technology use among older adults with type 1 diabetes: a preliminary process evaluation	36
Detecting the patient’s need for help with machine learning based on expressions	35
A new infodemiological approach through Google Trends: longitudinal analysis of COVID-19 scientific and infodemic names in Italy	35
An investigation of the constancy of effect in Cochrane systematic reviews in context with the assumptions for noninferiority trials	34
Classification of PR-positive and PR-negative subtypes in ER-positive and HER2-negative breast cancers based on pathway scores	33
Methodological assessment of systematic reviews of in-vitro dental studies	32
Neutral theory: applicability and neutrality of using generic health-related quality of life tools in diseases or conditions where specific tools are available	32
Interchangeability and optimization of heart rate methods for estimating oxygen uptake in ergometer cycling, level treadmill walking and running	32
CalScope: methodology and lessons learned for conducting a remote statewide SARS-CoV-2 seroprevalence study in California using an at-home dried blood spot collection kit and online survey	31
Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis	31
Comparison of reference distributions acquired by direct and indirect sampling techniques: exemplified with the Pediatric Reference Interval in China (PRINCE) study	31
Implementing multiple imputations for addressing missing data in multireader multicase design studies	30
Reporting and communication of sample size calculations in adaptive clinical trials: a review of trial protocols and grant applications	29
A framework to model global, regional, and national estimates of intimate partner violence	29
Pre-statistical harmonization of behavioral instruments across eight surveys and trials	28
Group sequential designs for pragmatic clinical trials with early outcomes: methods and guidance for planning and implementation	28
Evaluation of multiple imputation approaches for handling missing covariate information in a case-cohort study with a binary outcome	28
Modeling heart rate of individual and team manual handling with one hand using generalized additive mixed models	28
Ensuring cross-cultural data comparability by means of anchoring vignettes in heterogeneous refugee samples	27
Comparing outcomes from tailored meta-analysis with outcomes from a setting specific test accuracy study using routine data of faecal calprotectin testing for inflammatory bowel disease	27
Recruitment methods and yield rates in a clinical trial of physical exercise for older adults with hypertension—HAEL Study: a study within a trial	27
Addressing misclassification bias in vaccine effectiveness studies with an application to Covid-19	26
Promoting data harmonization to evaluate vaccine hesitancy in LMICs: approach and applications	25
Interdisciplinary sport injury research and the integration of qualitative and quantitative data	25
A gated group sequential design for seamless Phase II/III trial with subpopulation selection	25
Joint analysis of PK and immunogenicity outcomes using factorization model − a powerful approach for PK similarity study	25
Data quality in an HIV vaccine efficacy clinical trial in South Africa: through natural disasters and with discipline	24
Should RECOVERY have used response adaptive randomisation? Evidence from a simulation study	24
Modular literature review: a novel systematic search and review method to support priority setting in health policy and practice	24
Functional data analysis to characterize disease patterns in frequent longitudinal data: application to bacterial vaginal microbiota patterns using weekly Nugent scores and identification of pattern-s	24
A compartmental model for smoking dynamics in Italy: a pipeline for inference, validation, and forecasting under hypothetical scenarios	24
Safety analysis of new medications in clinical trials: a simulation study to assess the differences between cause-specific and subdistribution frameworks in the presence of competing events	23
Longitudinal mediation analysis with multilevel and latent growth models: a separable effects causal approach	22
The iterative bisection procedure: a useful tool for determining parameter values in data-generating processes in Monte Carlo simulations	22
Evaluation of Bayesian spatiotemporal infectious disease models for prospective surveillance analysis	22
Tracking modifications to implementation strategies: a case study from SNaP - a hybrid type III randomized controlled trial to scale up integrated systems navigation and psychosocial counseling for PW	22
Should multiple imputation be stratified by exposure group when estimating causal effects via outcome regression in observational studies?	22
A spatial obesity risk score for describing the obesogenic environment using kernel density estimation: development and parameter variation	21
MetaAnalyst: a user-friendly tool for metagenomic biomarker detection and phenotype classification	21
Adaptations for remote research work: a modified web-push strategy compared to a mail-only strategy for administering a survey of healthcare experiences	21
Mind the gap: covariate constrained randomisation can protect against substantial power loss in parallel cluster randomised trials	20

Application of the multiple dependent state sampling strategy to late adolescent suicide rates	20
Simulation analysis of an adjusted gravity model for hospital admissions robust to incomplete data	20
A Bayesian network perspective on neonatal pneumonia in pregnant women with diabetes mellitus	20
How well did the consensus methods apply in the guideline development of traditional Chinese medicine: a web-based survey in China	19
Construction of the Armenian Surname List (ASL) for public health research	19
Raking of data from a large Australian cohort study improves generalisability of estimates of prevalence of health and behaviour characteristics and cancer incidence	19
Patient regional index: a new way to rank clinical specialties based on outpatient clinics big data	19
IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy	19
Adaptive designs in critical care trials: a simulation study	18
regCOVID: Tracking publications of registered COVID-19 studies	18
Identification of difficult laryngoscopy using an optimized hybrid architecture	18
Sex-specific analysis of traumatic brain injury events: applying computational and data visualization techniques to inform prevention and management	18
Interpretable generalized neural additive models for mortality prediction of COVID-19 hospitalized patients in Hamadan, Iran	18
The INSPIRE Population Survey: development, dissemination and respondent characteristics	18
Reasons for missing evidence in rehabilitation meta-analyses: a cross-sectional meta-research study	17
Comparing statistical methods in assessing the prognostic effect of biomarker variability on time-to-event clinical outcomes	17
Correction of vaccine effectiveness derived from test-negative case–control studies	17
Standard of care for COVID-19 in randomized clinical trials registered in trial registries and published in preprint servers and scholarly journals: a cross-sectional study	17
Designing tailored maintenance strategies for systematic reviews and clinical practice guidelines using the Portfolio Maintenance by Test-Treatment (POMBYTT) framework	16
Combining propensity score methods with variational autoencoders for generating synthetic data in presence of latent sub-groups	16
Major mistakes or errors in the use of trial sequential analysis in systematic reviews or meta-analyses – the METSA systematic review	16
Multiple imputation to quantify misclassification in observational studies of the cognitively impaired: an application for pain assessment in nursing home residents	16
Gaps in the usage and reporting of multiple imputation for incomplete data: findings from a scoping review of observational studies addressing causal questions	16
Accelerating evidence synthesis for safety assessment through ClinicalTrials.gov platform: a feasibility study	16
Evaluation of the Fill-it-up-design to use historical control data in randomized clinical trials with two arm parallel group design	16
Constructing within and between hospital physician social networks for modeling physician research participation	15
Comparison between asymptotic and re-randomisation tests under non-proportional hazards in a randomised controlled trial using the minimisation method	15
The endorsement of general and artificial intelligence reporting guidelines in radiological journals: a meta-research study	15
The reporting of prognostic prediction models for obstetric care was poor: a cross-sectional survey of 10-year publications	15
Neutral theory: applicability and neutrality of clinical study endpoints where a disease-specific instrument is available	15
Responsiveness of different pain measures and recall periods in people undergoing surgery after a period of splinting for basal thumb joint osteoarthritis	15
Frequency-based rare diagnoses as a novel and accessible approach for studying rare diseases in large datasets: a cross-sectional study	15
Does imbalance in chest X-ray datasets produce biased deep learning approaches for COVID-19 screening?	14
coreSCD: multi-stakeholder consensus on core outcomes for sickle cell disease clinical trials	14
Developing survey weights to ensure representativeness in a national, matched cohort study: results from the children and young people with Long Covid (CLoCk) study	14
Growth mixture models: a case example of the longitudinal analysis of patient‐reported outcomes data captured by a clinical registry	14
Predicting the presence of depressive symptoms in the HIV-HCV co-infected population in Canada using supervised machine learning	14
Telephone peer recruitment and interviewing during a respondent-driven sampling (RDS) survey: feasibility and field experience from the first phone-based RDS survey among men who have sex with men in	14
Modelling of intensive care unit (ICU) length of stay as a quality measure: a problematic exercise	14
The impact of iterative removal of low-information cluster-period cells from a stepped wedge design	14
Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia	14
External validation of the American prediction model for incident type 2 diabetes in the Iranian population	14
Central data monitoring in the multicentre randomised SafeBoosC-III trial – a pragmatic approach	14
The validity, reliability and feasibility of four instruments for assessing the consciousness of stroke patients in a neurological intensive care unit compared	14
Bayesian mendelian randomization with study heterogeneity and data partitioning for large studies	14
Effects of different invitation strategies on participation in a cohort study of Iranian public sector employees: a cluster randomized trial	13
Guidelines are needed for studies of pre-treatment HIV drug resistance: a methodological study	13
Contextual effects: how to, and how not to, quantify them	13
The analysis and reporting of multiple outcomes in mental health trials: a methodological systematic review	13
Cluster randomised trials with a binary outcome and a small number of clusters: comparison of individual and cluster level analysis method	13
Time and change: a typology for presenting research findings in qualitative longitudinal research	13
The use of sequential multiple assignment randomized trials (SMARTs) in physical activity interventions: a systematic review	13
Robustness assessment of regressions using cluster analysis typologies: a bootstrap procedure with application in state sequence analysis	13
Are morbidity and mortality estimates from randomized controlled trials externally valid? A comparison of outcomes among infants enrolled into an RCT or a cohort study in Botswana	13
Reporting of interventional clinical trial results in an academic center: a survey of completed studies	13
CRIME-Q—a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research	13
Addressing treatment switching in the ALTA-1L trial with g-methods: exploring the impact of model specification	12
Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer	12
Recruitment into antibody prevalence studies: a randomized trial of postcards vs. letters as invitations	12
Systematic reviews and meta-analysis published in indexed Portuguese medical journals: time trends and critical appraisal	12
Methodological aspects for accelerometer-based assessment of physical activity in heart failure and health	12
Toward value-based care using cost mining: cost aggregation and visualization across the entire colorectal cancer patient pathway	12
Effects of missing data imputation methods on univariate blood pressure time series data analysis and forecasting with ARIMA and LSTM	12
External validation of existing dementia prediction models on observational health data	12
Grouped data with survey revision	12
A meta-review demonstrates improved reporting quality of qualitative reviews following the publication of COREQ- and ENTREQ-checklists, regardless of modest uptake	12
Estimation of marginal structural models under irregular visits and unmeasured confounder: calibrated inverse probability weights	12
Research monitoring practices in critical care research: a survey of current state and attitudes	12
Fast and optimal algorithm for case-control matching using registry data: application on the antibiotics use of colorectal cancer patients	12
Systematic review and meta analysis of differential attrition between active and control arms in randomized controlled trials of lifestyle interventions in chronic disease	11
Satisfaction and experience with colorectal cancer screening: a systematic review of validated patient reported outcome measures	11
Flexible Bayesian semiparametric mixed-effects model for skewed longitudinal data	11
A comparison of statistical methods for modeling count data with an application to hospital length of stay	11
An evaluation of computational methods for aggregate data meta-analyses of diagnostic test accuracy studies	11
Similarities, reliability and gaps in assessing the quality of conduct of systematic reviews using AMSTAR-2 and ROBIS: systematic survey of nutrition reviews	11
Making implementation science more real	11
Evaluating the current methodological practices and issues in existing literature in pooling complex surveys: a systematic review	11
Risk prediction in multicentre studies when there is confounding by cluster or informative cluster size	11
Choices of measures of association affect the visualisation and composition of the multimorbidity networks	11
Estimating restricted mean survival time and expected life-years lost in the presence of competing risks within flexible parametric survival models	11

The effect of home visits as an additional recruitment step on the composition of the final sample: a cross-sectional analysis in two study centers of the German National Cohort (NAKO)	11
The optimal approach for retrieving systematic reviews was achieved when searching MEDLINE and Epistemonikos in addition to reference checking: a methodological validation study	11
Test–retest reliability of selected HBSC items in Vietnam: well-being, physical and sedentary activities, and eating behaviours	11
Sample size requirements are not being considered in studies developing prediction models for binary outcomes: a systematic review	11
Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods	11
Bayesian Mendelian randomization with an interval causal null hypothesis: ternary decision rules and loss function calibration	10
Multistate Markov chain modeling for child undernutrition transitions in Ethiopia: a longitudinal data analysis, 2002–2016	10
Inverse probability weighting to handle attrition in cohort studies: some guidance and a call for caution	10
geessbin: an R package for analyzing small-sample binary data using modified generalized estimating equations with bias-adjusted covariance estimators	10
Comparing current and emerging practice models for the extrapolation of survival data: a simulation study and case-study	10
Internal validation of self-reported case numbers in hospital quality reports: preparing secondary data for health services research	10
Multiple imputation using auxiliary imputation variables that only predict missingness can increase bias due to data missing not at random	10
Weighted metrics are required when evaluating the performance of prediction models in nested case–control studies	10
Motivations for enrollment in a COVID-19 ring-based post-exposure prophylaxis trial: qualitative examination of participant experiences	10
Predictive P-score for treatment ranking in Bayesian network meta-analysis	10
Application of the estimand framework for an emulated trial using reference based multiple imputation to investigate informative censoring	10
Predicting lung cancer survival prognosis based on the conditional survival bayesian network	10
The impact of different censoring methods for analyzing survival using real-world data with linked mortality information: a simulation study	10
Comparative age-period-cohort analysis	10
unmconf : an R package for Bayesian regression with unmeasured confounders	10
Analyzing missingness patterns in real-world data using the SMDI toolkit: application to a linked EHR-claims pharmacoepidemiology study	10
Towards realist-informed ripple effects mapping (RREM): positioning the approach	10
Forecasting COVID-19 cases using time series modeling and association rule mining	10
Two-step spatiotemporal anomaly detection corrected for lag reporting time with application to real-time dengue surveillance in Thailand	10
FOUNTAIN: a modular research platform for integrated real-world evidence generation	10
Using a distribution-based approach and systematic review methods to derive minimum clinically important differences	10
Prediction of congenital heart disease for newborns: comparative analysis of Holt-Winters exponential smoothing and autoregressive integrated moving average models	9
The methodological quality assessment of systematic reviews/meta-analyses of chronic prostatitis/chronic pelvic pain syndrome using AMSTAR2	9
Machine learning in medicine: a practical introduction to natural language processing	9
Power and sample size calculation for incremental net benefit in cost effectiveness analyses with applications to trials conducted by the Canadian Cancer Trials Group	9
Use and misuse of random forest variable importance metrics in medicine: demonstrations through incident stroke prediction	9
More than one third of clinical practice guidelines on low back pain overlap in AGREE II appraisals. Research wasted?	9
Modelling wound area in studies of wound healing interventions	9
From simple to even simpler, but not too simple: a head-to-head comparison of the Better-Worse and Drop-Down methods for measuring patient health status	9
Minimal important difference, patient acceptable symptom state and longitudinal validity of oxford elbow score and the quickDASH in patients with tennis elbow	9
Concordance rate of a four-quadrant plot for repeated measurements	9
Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods	9
A simple pooling method for variable selection in multiply imputed datasets outperformed complex methods	9
Statistical methods in the analysis of multicentre HIV randomized controlled trials in the African region: a scoping review	9
External control arm analysis: an evaluation of propensity score approaches, G-computation, and doubly debiased machine learning	9
What do stroke survivors’ value about participating in research and what are the most important research problems related to stroke or transient ischemic attack (TIA)? A survey	9
Inference following multiple imputation for generalized additive models: an investigation of the median p-value rule with applications to the Pulmonary Hypertension Association Registry and Colorado C	9
Quality appraisal for systematic literature reviews of health state utility values: a descriptive analysis	9
Relationship between patient experience and hospital readmission: system-level survey with deterministic data linkage method	9
Correction: Real‑world data: a brief review of the methods, applications, challenges and opportunities	8
Open science saves lives: lessons from the COVID-19 pandemic	8
Classifying information-sharing methods	8
Technologies for frailty, comorbidity, and multimorbidity in older adults: a systematic review of research designs	8
The role of the estimand framework in the analysis of patient-reported outcomes in single-arm trials: a case study in oncology	8
Empirical assessment of alternative methods for identifying seasonality in observational healthcare data	8
Strategies for assessing the impact of loss to follow-up on estimates of neurodevelopmental impairment in a very preterm cohort at 2 years of age	8
A scoping review of statistical methods in studies of biomarker-related treatment heterogeneity for breast cancer	8
Correction: Accounting for expected attrition in the planning of cluster randomized trials for assessing treatment effect heterogeneity	8
Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study	8
Application of machine learning in predicting hospital readmissions: a scoping review of the literature	8
Restrictions and their reporting in systematic reviews of effectiveness: an observational study	8
Three new methodologies for calculating the effective sample size when performing population adjustment	8
The Danish Drowning Cohort: Utstein-style data from fatal and non-fatal drowning incidents in Denmark	8
Applying a novel approach to scoping review incorporating artificial intelligence: mapping the natural history of gonorrhoea	8
Design and analysis of outcomes following SARS-CoV-2 infection in veterans	8
Causal effect of chemotherapy received dose intensity on survival outcome: a retrospective study in osteosarcoma	8
Correction: Analysis of zero inflated dichotomous variables from a Bayesian perspective: application to occupational health	8
Outbreak detection algorithms based on generalized linear model: a review with new practical examples	8
Evaluating complex interventions in context: systematic, meta-narrative review of case study approaches	8
Correction: In health research publications, the number of authors is strongly associated with collective self-citations but less so with citations by others	8
Stability analysis and numerical evaluations of a COVID-19 model with vaccination	8
Correction to: A tutorial on pilot studies: the what, why and how	8
How to specify healthcare process improvements collaboratively using rapid, remote consensus-building: a framework and a case study of its application	8
Correction: Multi‑arm multi‑stage (MAMS) randomised selection designs: impact of treatment selection rules on the operating characteristics	8
An analysis of published study designs in PubMed prisoner health abstracts from 1963 to 2023: a text mining study	7
Comparison of correctly and incorrectly classified patients for in-hospital mortality prediction in the intensive care unit	7
Confounding-adjustment methods for the causal difference in medians	7
Estimating age-specific COVID-19 fatality risk and time to death by comparing population diagnosis and death patterns: Australian data	7
Improving retention of community-recruited participants in HIV prevention research through Saturday household visits; findings from the HPTN 071 (PopART) study in South Africa	7
Studies with statistically significant effect estimates are more frequently published compared to non-significant estimates in oral health journals	7
Development and validation of paired MEDLINE and Embase search filters for cost-utility studies	7
Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches	7
A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Pri	7
Using group testing in a two-phase epidemiologic design to identify the effects of a large number of antibody reactions on disease risk	7
Assessing the ability of an instrumental variable causal forest algorithm to personalize treatment evidence using observational data: the case of early surgery for shoulder fracture	7
Segmentation of patients with small cell lung cancer into responders and non-responders using the optimal cross-validation technique	7
Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART	7
RITS: a toolbox for assessing complex interventions via interrupted time series models	7
Arrhythmia detection by the graph convolution network and a proposed structure for communication between cardiac leads	7
Power calculation for detecting interaction effect in cross-sectional stepped-wedge cluster randomized trials: an important tool for disparity research	7
Effect of alcohol consumption on breast cancer: probabilistic bias analysis for adjustment of exposure misclassification bias and confounders	7
Capturing the variety of clinical pathways in patients with schizophrenic disorders through state sequences analysis	7
Problematic meta-analyses: Bayesian and frequentist perspectives on combining randomized controlled trials and non-randomized studies	7
Two-stage sampling in the estimation of growth parameters and percentile norms: sample weights versus auxiliary variable estimation	7
Shifting research culture to address the mismatch between where trials recruit and where populations with the most disease live: a qualitative study	7
Revisiting methods for modeling longitudinal and survival data: Framingham Heart Study	7
Comparison of prevalence and exposure-disease associations using self-report and hospitalization data among enrollees of the world trade center health registry	7
Joint modelling of multivariate longitudinal clinical laboratory safety outcomes, concomitant medication and clinical adverse events: application to artemisinin-based treatment during pregnancy clinic	7
Incentive delivery timing and follow-up survey completion in a prospective cohort study of injured children: a randomized experiment comparing prepaid and postpaid incentives	7
Measuring the impact of zero-cases studies in evidence synthesis practice using the harms index and benefits index (Hi-Bi)	7