OOIR: Observatory of International Research

Papers

(The median citation count of BMC Immunology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways	124
Lipopolysaccharide- TLR-4 Axis regulates Osteoclastogenesis independent of RANKL/RANK signaling	42
Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients	38
Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction	30
Prognostic role of red blood cell distribution width in patients with sepsis: a systematic review and meta-analysis	28
Association of TIM-3 expression with glucose metabolism in Jurkat T cells	28
Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist	26
Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes	26
The relationship between symptom burden and systemic inflammation differs between male and female athletes following concussion	26
Vaccinomic approach for novel multi epitopes vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)	25
Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway	24
Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells	20
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis	20
The effects of the probiotic cocktail on modulation of the NF-kB and JAK/STAT signaling pathways involved in the inflammatory response in bowel disease model	20
Neutrophil extracellular traps are present in the airways of ENaC-overexpressing mice with cystic fibrosis-like lung disease	18
Optimizing interleukin-2 concentration, seeding density and bead-to-cell ratio of T-cell expansion for adoptive immunotherapy	18
Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells	18
Identification of differentially expressed circulating exosomal lncRNAs in IgA nephropathy patients	17
Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p	16
D-mannose ameliorates autoimmune phenotypes in mouse models of lupus	16
A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood d	15
Interleukin 4 gene polymorphism (−589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies	15
Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and other hematological parameters in psoriasis patients	15
Epitherapy and immune checkpoint blockade: using epigenetic reinvigoration of exhausted and dysfunctional T cells to reimburse immunotherapy response	14
Enhancement of Zika virus infection by antibodies from West Nile virus seropositive individuals with no history of clinical infection	14

Humoral and cellular response to SARS-CoV-2 BNT162b2 mRNA vaccine in hemodialysis patients	14
CXCL9 secreted by tumor-associated dendritic cells up-regulates PD-L1 expression in bladder cancer cells by activating the CXCR3 signaling	14
The role of β2 integrin in dendritic cell migration during infection	13
The seroprevalence and kinetics of IgM and IgG in the progression of COVID-19	13
Positive staining of the immunoligand B7-H6 in abnormal/transformed keratinocytes consistently accompanies the progression of cervical cancer	12
Membrane tension sensing molecule-FNBP1 is a prognostic biomarker related to immune infiltration in BRCA, LUAD and STAD	12
Comprehensive evaluation of the effects of long-term cryopreservation on peripheral blood mononuclear cells using flow cytometry	12
Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers	12
Genomic, microbial and environmental standardization in animal experimentation limiting immunological discovery	11
Identification of active small-molecule modulators targeting the novel immune checkpoint VISTA	10
Characteristics and reference ranges of CD4+T cell subpopulations among healthy adult Han Chinese in Shanxi Province, North China	10
Differential polarization and the expression of efferocytosis receptor MerTK on M1 and M2 macrophages isolated from coronary artery disease patients	10
Differential long non-coding RNA expression profile and function analysis in primary Sjogren’s syndrome	10
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation	10
Natural killer cell levels in adults living with type 2 diabetes: a systematic review and meta-analysis of clinical studies	10
Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses	10
Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis	10
Blockade of exosome generation by GW4869 inhibits the education of M2 macrophages in prostate cancer	10
CD16 expression on neutrophils predicts treatment efficacy of capecitabine in colorectal cancer patients	10
Downregulation of NKG2DLs by TGF-β in human lung cancer cells	10
Transcriptomics of type 2 diabetic and healthy human neutrophils	10
Pharmacological activation of rev-erbα suppresses LPS-induced macrophage M1 polarization and prevents pregnancy loss	10
Allo-HSCT compared with immunosuppressive therapy for acquired aplastic anemia: a system review and meta-analysis	10
Transmembrane signaling molecules play a key role in the pathogenesis of IgA nephropathy: a weighted gene co-expression network analysis study	9
Chemokine CXCL1 as a potential marker of disease activity in systemic lupus erythematosus	9
Serum IL-35 is decreased in overweight patients with rheumatoid arthritis: its correlation with Th1/Th2/Th17-related cytokines	9
Soluble cytotoxic T-lymphocyte–associated antigen 4 (sCTLA-4) as a potential biomarker for diagnosis and evaluation of the prognosis in Glioma	9
Tertiary lymphoid structure related B-cell IgE isotype switching and secondary lymphoid organ linked IgE production in mouse allergy model	9
Increased Interleukin-35 suppresses peripheral CD14+ monocytes function in patients with Kawasaki disease	9
The augment of regulatory T cells undermines the efficacy of anti-PD-L1 treatment in cervical cancer	9
Comparative efficacy of glucocorticoid receptor agonists on Th2 cell function and attenuation by progesterone	9
Mutant glucocorticoid receptor binding elements on the interleukin-6 promoter regulate dexamethasone effects	8
Formation of ultralong DH regions through genomic rearrangement	8
JAK inhibitors impair GM-CSF-mediated signaling in innate immune cells	8
Assessing the expression of immunosuppressive cytokines in the newly diagnosed systemic lupus Erythematosus patients: a focus on B cells	8
Increased serum IL-2, IL-4, IL-5 and IL-12p70 levels in AChR subtype generalized myasthenia gravis	8
Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model	8
Intratumoral regulatory T cells from colon cancer patients comprise several activated effector populations	8
Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch	8
Type 2 and type 3 innate lymphoid cells at the maternal-fetal interface: implications in preterm birth	8
STAT3 and SPI1, may lead to the immune system dysregulation and heterotopic ossification in ankylosing spondylitis	7
Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy	7
Association between serum markers of the humoral immune system and inflammation in the Swedish AMORIS study	7
Anti-inflammatory protein TNFα-stimulated gene-6 (TSG-6) reduces inflammatory response after brain injury in mice	7
The effects of human pregnancy-specific β1-glycoprotein preparation on Th17 polarization of CD4+ cells and their cytokine profile	7
Elevated expansion of follicular helper T cells in peripheral blood from children with acute measles infection	7
Assessment of CD27 expression on T-cells as a diagnostic and therapeutic tool for patients with smear-negative pulmonary tuberculosis	7
Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood	7
ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses	7
Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer	7

Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease	7
What is the response profile of deciduous pulp fibroblasts stimulated with E. coli LPS and E. faecalis LTA?	7
Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2	6
Restoration of dendritic cell homeostasis and Type I/Type III interferon levels in convalescent COVID-19 individuals	6
Can presepsin uniformly respond to various pathogens? - an in vitro assay of new sepsis marker -	6
A novel 4 immune-related genes as diagnostic markers and correlated with immune infiltrates in major depressive disorder	6
Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection	6
Cytokine profile in the sputum of subjects with post-tuberculosis airflow obstruction and in those with tobacco related chronic obstructive pulmonary disease	6
Regulatory and effector T cell subsets in tumor-draining lymph nodes of patients with squamous cell carcinoma of head and neck	6
Selenium-related nutritional status in patients with common variable immunodeficiency: association with oxidative stress and atherosclerosis risk	6
Efficacy of tocilizumab therapy in a patient with severe pancytopenia associated with a STAT3 gain-of-function mutation	6
Reduction of peripheral regulatory T cells in active rheumatoid arthritis patients with coronary artery disease	6
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer	6
Decreased glycolysis induced dysfunction of NK cells in Henoch-Schonlein purpura patients	5
Blood CD3-(CD56 or 16)+ natural killer cell distributions are heterogeneous in healthy adults and suppressed by azathioprine in patients with ANCA-associated vasculitides	5
CD19+CD24hiCD38hi regulatory B cells deficiency revealed severity and poor prognosis in patients with sepsis	5
Human CD8+CD28− T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo	5
Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress	5
Soluble programmed death molecule 1 (sPD-1) as a predictor of interstitial lung disease in rheumatoid arthritis	5
Trastuzumab immunogenicity development in patients’ sera and in laboratory animals	5
Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fcγ- receptor mediated phagocytosis in mouse and human cells	5
Subcutaneous immunoglobulin in primary immunodeficiency – impact of training and infusion characteristics on patient-reported outcomes	5
Immunogenicity and protective efficacy of a live, oral cholera vaccine formulation stored outside-the-cold-chain for 140 days	5
Specific humoral response in cancer patients treated with a VEGF-specific active immunotherapy procedure within a compassionate use program	5
The inhibitory receptor Tim-3 fails to suppress IFN-γ production via the NFAT pathway in NK-cell, unlike that in CD4+ T cells	5
CD100 modulates cytotoxicity of CD8+ T cells in patients with acute myocardial infarction	5
EGR2 is elevated and positively regulates inflammatory IFNγ production in lupus CD4+ T cells	4
A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren’s syndrome	4
Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort	4
The correlation of EZH2 expression with the progression and prognosis of hepatocellular carcinoma	4
Sex and FOXP3 gene rs2232365 polymorphism may be associated with the clinical and pathological aspects of chronic viral diseases	4
The proportion and phenotypic changes of CD4+CD25−Foxp3+ T cells in patients with untreated rheumatoid arthritis	4
Nitro-fatty acids decrease type I interferons and monocyte chemoattractant protein 1 in ex vivo models of inflammatory arthritis	4
Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections	4
Low-dose interleukin-2 can improve salivary secretion but not lymphocyte infiltration of salivary glands in a murine model of Sjögren’s syndrome	4
The impact of neutrophil extracellular trap from patients with systemic lupus erythematosus on the viability, CD11b expression and oxidative burst of healthy neutrophils	4
The immune subtypes and landscape of sarcomas	4
Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity	4
Determining if T cell antigens are naturally processed and presented on HLA class I molecules	4
TREM2 promotes natural killer cell development in CD3−CD122+NK1.1+ pNK cells	4
Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food	4
Oxidative stress-related circulating miRNA-27a is a potential biomarker for diagnosis and prognosis in patients with sepsis	4
CD4, CD8 and natural killer cells are depressed in patients with alopecia areata: their association with disease activity	4
RelB regulates the homeostatic proliferation but not the function of Tregs	4
Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cells	4
DDX1 is a prognostic biomarker and correlates with immune infiltrations in hepatocellular carcinoma	3
Changes in inflammatory factors in the Brown Norway rat model of food allergy	3
The effect of probiotics on immunogenicity of spermatozoa in couples suffering from recurrent spontaneous abortion	3
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor	3
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps	3
Utility of basophil activation test for predicting the outcome of wheezing in children: a pilot study	3
Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice	3
Prevalence of human leukocyte antigen HLA-B*57:01 in individuals with HIV in West and Central Africa	3
Transcriptomic responses of bat cells to European bat lyssavirus 1 infection under conditions simulating euthermia and hibernation	3
Predicting the allergenicity of legume proteins using a PBMC gene expression assay	3
Factors associated with IgG levels in adults with IgG subclass deficiency	3
Activin a suppresses peripheral CD8+ T lymphocyte activity in acute-phase Kawasaki disease	3
Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa	3
A longitudinal study of humoral immune responses induced by a 3-dose inactivated COVID-19 vaccine in an observational, prospective cohort	3
PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation	3
Ex vivo mRNA expression of toll-like receptors during latent tuberculosis infection	3
NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis	3
Comprehensive analysis of immunoglobulin and clinical variables identifies functional linkages and diagnostic indicators associated with Behcet’s disease patients receiving immunomodulatory treatment	3
Phosphate starvation enhances phagocytosis of Mycobacterium bovis/BCG by macrophages	3
The potential pathogenic roles of S100A8/A9 and S100A12 in patients with MPO-ANCA-positive vasculitis	3
Type 2 innate lymphoid cells from Id1 transgenic mice alleviate skin manifestations of graft-versus-host disease	3