Nature Reviews Molecular Cell Biology

Papers
(The median citation count of Nature Reviews Molecular Cell Biology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents2155
Gene regulation by long non-coding RNAs and its biological functions2116
Ferroptosis: mechanisms, biology and role in disease1952
Mechanisms of SARS-CoV-2 entry into cells1388
Guidelines and definitions for research on epithelial–mesenchymal transition1081
Mechanisms, regulation and functions of the unfolded protein response1037
Human organoids: model systems for human biology and medicine1002
RNA delivery by extracellular vesicles in mammalian cells and its applications915
Molecular mechanisms and cellular functions of cGAS–STING signalling774
The expanding regulatory mechanisms and cellular functions of circular RNAs766
Cellular senescence in ageing: from mechanisms to therapeutic opportunities721
The cell biology of mitochondrial membrane dynamics667
The regulation and functions of DNA and RNA G-quadruplexes660
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond556
NAD+ metabolism and its roles in cellular processes during ageing540
A guide to machine learning for biologists535
Global view of human protein glycosylation pathways and functions519
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing496
ERK signalling: a master regulator of cell behaviour, life and fate488
Reactive oxygen species signalling in plant stress responses463
Cell cycle control in cancer454
Mechanisms governing autophagosome biogenesis453
The nucleolus as a multiphase liquid condensate434
The tubulin code and its role in controlling microtubule properties and functions431
Emerging connectivity of programmed cell death pathways and its physiological implications426
A framework for understanding the functions of biomolecular condensates across scales416
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology409
Applications of CRISPR–Cas in agriculture and plant biotechnology395
Mechanisms of bone development and repair390
The clearance of dead cells by efferocytosis363
Challenges and directions in studying cell–cell communication by extracellular vesicles327
RNA contributions to the form and function of biomolecular condensates325
Cell fate specification and differentiation in the adult mammalian intestine274
Mechanisms controlling pancreatic islet cell function in insulin secretion257
The expanding world of tRNA modifications and their disease relevance256
The ageing epigenome and its rejuvenation253
Molecular mechanisms of dietary restriction promoting health and longevity251
Long non-coding RNAs: definitions, functions, challenges and recommendations250
Genome folding through loop extrusion by SMC complexes249
Plant hormone regulation of abiotic stress responses239
Diversity and versatility of p38 kinase signalling in health and disease237
The assembly, regulation and function of the mitochondrial respiratory chain230
The principles of directed cell migration226
Quality control of the mitochondrial proteome215
The roles of histone variants in fine-tuning chromatin organization and function213
Modulation of cellular processes by histone and non-histone protein acetylation207
The aetiology and molecular landscape of insulin resistance205
The molecular basis and disease relevance of non-homologous DNA end joining205
Machinery, regulation and pathophysiological implications of autophagosome maturation202
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design201
The cellular and functional complexity of thermogenic fat190
The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication188
The molecular principles of gene regulation by Polycomb repressive complexes186
The roles of Polycomb repressive complexes in mammalian development and cancer185
The plasticity of DNA replication forks in response to clinically relevant genotoxic stress181
Crosstalk between mechanotransduction and metabolism180
Regulation of human telomerase in homeostasis and disease178
Understanding 3D genome organization by multidisciplinary methods171
Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression170
Target gene-independent functions of MYC oncoproteins169
Mechanisms and regulation of protein synthesis in mitochondria158
Intracellular mRNA transport and localized translation157
Direct cell reprogramming: approaches, mechanisms and progress156
Programmed and self-organized flow of information during morphogenesis150
Molecular mechanisms and consequences of mitochondrial permeability transition145
The mechanisms and roles of selective autophagy in mammals144
Proteomic and interactomic insights into the molecular basis of cell functional diversity141
MicroRNA-mediated regulation of glucose and lipid metabolism141
Molecular mechanisms underlying nucleotide repeat expansion disorders136
Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics130
Roles of transposable elements in the regulation of mammalian transcription125
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance125
Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery124
Control of satellite cell function in muscle regeneration and its disruption in ageing123
Nuclear compartmentalization as a mechanism of quantitative control of gene expression122
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization120
Liver regeneration and inflammation: from fundamental science to clinical applications114
Membrane and organelle dynamics during cell division114
Causes and consequences of RNA polymerase II stalling during transcript elongation114
Human topoisomerases and their roles in genome stability and organization110
Regulation of membrane protein structure and function by their lipid nano-environment110
Regulation of microtubule dynamics, mechanics and function through the growing tip106
Cellular origins of dsRNA, their recognition and consequences104
New insights into activation and function of the AMPK104
Mechanics and functional consequences of nuclear deformations103
Karyopherin-mediated nucleocytoplasmic transport98
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids94
The mechanisms of integral membrane protein biogenesis93
Phosphoinositides as membrane organizers92
Cellular functions of the protein kinase ATM and their relevance to human disease92
Context-specific regulation of extracellular vesicle biogenesis and cargo selection91
The emerging mechanisms and functions of microautophagy85
Signalling mechanisms and cellular functions of SUMO83
Apical–basal polarity and the control of epithelial form and function80
Pioneer factors as master regulators of the epigenome and cell fate80
Roles of RNA silencing in viral and non-viral plant immunity and in the crosstalk between disease resistance systems79
Ageing and rejuvenation of tissue stem cells and their niches79
A guide to membraneless organelles and their various roles in gene regulation79
Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining77
A tale of non-canonical tails: gene regulation by post-transcriptional RNA tailing76
Autophagy and autophagy-related pathways in cancer75
Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions74
An expanded lexicon for the ubiquitin code72
Gene regulation in time and space during X-chromosome inactivation72
The physiology of alternative splicing71
Plant and animal small RNA communications between cells and organisms69
Context-specific regulation and function of mRNA alternative polyadenylation65
The Mediator complex as a master regulator of transcription by RNA polymerase II64
Translational control of stem cell function64
Biochemical and mechanical regulation of actin dynamics64
Interplay between mechanics and signalling in regulating cell fate63
Cell–extracellular matrix mechanotransduction in 3D57
Endocytosis in the context-dependent regulation of individual and collective cell properties56
Cell–cell interfaces as specialized compartments directing cell function56
Spindle positioning and its impact on vertebrate tissue architecture and cell fate53
Author Correction: Gene regulation by long non-coding RNAs and its biological functions53
Acquired genetic changes in human pluripotent stem cells: origins and consequences52
The technological landscape and applications of single-cell multi-omics51
COVID-19 management in light of the circadian clock51
Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins51
Molecular and cellular basis of genetically inherited skeletal muscle disorders50
Emerging roles and functional mechanisms of PIWI-interacting RNAs50
Mechanisms of mitochondrial respiratory adaptation50
Selective motor activation in organelle transport along axons48
COVID-19: organoids go viral48
Mechanisms of microtubule organization in differentiated animal cells48
Ubiquitin ligases: guardians of mammalian development47
Metabolites as signalling molecules41
Regulation, functions and transmission of bivalent chromatin during mammalian development40
Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases39
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways39
Mechanical regulation of early vertebrate embryogenesis39
Mechanisms and roles of podosomes and invadopodia39
Cytoskeletal control of early mammalian development36
Transcriptional control of energy metabolism by nuclear receptors34
Principles and dynamics of spindle assembly checkpoint signalling34
Deep learning shapes single-cell data analysis32
Regulation of axonal regeneration after mammalian spinal cord injury31
Effects of aneuploidy on cell behaviour and function31
Metabolic regulation of somatic stem cells in vivo30
Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity28
Aneuploidy in mammalian oocytes and the impact of maternal ageing26
Cell competition in development, homeostasis and cancer26
Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes25
The many regulators of epithelial−mesenchymal transition25
Keeping chromatin in the loop(s)25
Generation of nanoscopic membrane curvature for membrane trafficking24
Mechano-genomic regulation of coronaviruses and its interplay with ageing23
Mechanisms of BCL-2 family proteins in mitochondrial apoptosis23
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex22
Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases21
Regulation and functions of non-m6A mRNA modifications20
Identification of non-coding silencer elements and their regulation of gene expression20
Lipid rafts come of age19
Transcriptional networks controlling stromal cell differentiation19
AMPK against NASH17
CRISPR–Cas9 wins Nobel16
The nature of blood(y) extracellular vesicles16
Exercise metabolism and adaptation in skeletal muscle16
Lipids as the key to understanding α-synuclein behaviour in Parkinson disease16
Applications and ethics of computer-designed organisms16
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens15
Biology and therapeutic targeting of vascular endothelial growth factor A15
Mechanisms underlying spindle assembly and robustness15
Old and new models for the study of human ageing15
Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition15
The role of ordered cooperative assembly in biomolecular condensates15
Cellular functions of eukaryotic RNA helicases and their links to human diseases15
The prospects and opportunities of protein structure prediction with AI14
RNA polymerase II transcription compartments: from multivalent chromatin binding to liquid droplet formation?14
Cellular and molecular mechanisms of Hedgehog signalling14
Mechanisms controlling cellular and systemic iron homeostasis14
Let’s talk about (biological) sex13
The molecular basis for cellular function of intrinsically disordered protein regions13
CircRNAs in lifespan13
Genome control by SMC complexes12
Publisher Correction: Plant hormone regulation of abiotic stress responses12
Defining the functions of PIWI-interacting RNAs12
Revisiting small RNA movement in plants11
Structural and functional complexity of HSP90 in cellular homeostasis and disease11
The network effect: studying COVID-19 pathology with the Human Cell Atlas11
Reassessing the relationship between mRNA levels and protein abundance in exercised skeletal muscles10
Defective mitochondria ignite the SASP10
Mechanisms of substrate processing during ER-associated protein degradation10
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease9
Author Correction: Molecular mechanisms underlying nucleotide repeat expansion disorders9
Author Correction: Applications of CRISPR–Cas in agriculture and plant biotechnology8
Understanding mechanisms of antioxidant action in health and disease8
Publisher Correction: Emerging roles and functional mechanisms of PIWI- interacting RNAs7
Solutes as controllers of endomembrane dynamics7
Foundations of ER-phagy regulation7
Drugs enter a liquid phase6
Mitochondrial ROS drive cell cycle progression6
Author Correction: Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics6
Die hard: resilient RNAs in the blood6
RILP gets cleaved and exosomes leave6
Making more exosomes6
Small extracellular vesicles combat senescence5
Why novel mRNA modifications are so challenging and what we can do about it5
Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology5
Control of stem cell renewal and fate by YAP and TAZ5
Publisher Correction: Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization5
New guidelines for embryo and stem cell research5
Author Correction: Intracellular mRNA transport and localized translation5
Uncovering SARS-CoV-2 kidney tropism5
Intermittent fasting is gaining interest fast5
mRNA translation in stress granules is not uncommon5
How the α-helix got its name5
microRNA communication in plants5
The multiple links between actin and mitochondria5
Activation of human endogenous retroviruses and its physiological consequences4
The RNA world ‘hypothesis’4
EVs promote stemness4
Cellular basis for SARS-CoV-2 infection4
Shaping the stem cell field4
Imaging DNA double-strand breaks — are we there yet?4
Who did what: changing how science papers are written to detail author contributions4
Heterochromatin definition and function4
Lysosome transport interrupted4
Human pluripotent stem cells: derivation and applications4
Mechanisms of SNARE proteins in membrane fusion4
Author Correction: Regulation of membrane protein structure and function by their lipid nano-environment4
The BCL-2 family saga4
Stress fibres fuel glycolysis3
Sorting out microtubule-based transport3
Am-bivalency towards DNA methylation3
The molecular basis of translation initiation and its regulation in eukaryotes3
Author Correction: Mitochondrial proteins: from biogenesis to functional networks3
Migrasomes promote angiogenesis3
Science Twitter — navigating change in science communication3
Engineering cellular symphonies out of transcriptional noise3
Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death3
Damaged mitochondria are discarded via migrasomes3
Publisher Correction: Applications of CRISPR–Cas in agriculture and plant biotechnology3
Spot in a drop: mutations in aberrant condensates3
Context-dependent TGFβ family signalling in cell fate regulation3
Elastin phase separation — structure or disorder?3
How green is your science? The race to make laboratories sustainable3
First demonstration of miRNA-dependent mRNA decay3
50+ shades of EMT in 20 years of embryo−cancer bonding3
Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer3
DNA modifications walk a fine line between epigenetics and mutagenesis3
Path to autophagy therapeutics with Beth Levine3
Single-cell lipidomics reveals the organizing principle of cell fate decision3
A mistranslation-prone transcriptome underlying polyglutamine expansion diseases3
The contribution of databases towards understanding the universe of long non-coding RNAs3
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