Nature Reviews Molecular Cell Biology

Papers
(The median citation count of Nature Reviews Molecular Cell Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
The translation m(o)TOR that propels regeneration2240
When senescence generates pluripotent stem cells1163
Tightening the epithelium to control signalling1130
Transfection reflections: fit-for-purpose delivery of nucleic acids1127
A dynamic culture system that models the intricacy of the mammary gland976
From trans-splicing discovery and onwards, trypanosomes lead the way913
Re-sizing of nuclear pores721
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways703
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids655
Mechanisms of substrate processing during ER-associated protein degradation553
The aetiology and molecular landscape of insulin resistance545
Modulation of cellular processes by histone and non-histone protein acetylation498
Understanding mechanisms of antioxidant action in health and disease473
How proteins sense their cellular environment459
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment450
Decoding the Ca2+ signal for salt tolerance431
Resilience through selective translation391
Damaged mitochondria are discarded via migrasomes363
The phosphoinositide PI5P inhibits the Hippo pathway effector YAP355
Endocytosis in the context-dependent regulation of individual and collective cell properties350
Mechanism and regulation of kinesin motors330
The emerging mechanisms and functions of microautophagy329
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance324
Publisher Correction: Plant hormone regulation of abiotic stress responses317
New insights into activation and function of the AMPK312
Spindle positioning and its impact on vertebrate tissue architecture and cell fate311
The healing role of gasdermin B in IBD287
CRISPR–Cas applications in agriculture and plant research286
Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation283
Telomere function and regulation from mouse models to human ageing and disease282
C-degron mimicry confers E3 ligase selectivity279
Bookmarking pluripotency genes278
Silencing centromeres with age277
Voices of the new generation: open science is good for science (and for you)273
The discovery of oncogene-induced senescence272
Studying lysosomal function and dysfunction using LysoIP272
Regulation, functions and transmission of bivalent chromatin during mammalian development269
Regulation of membrane protein structure and function by their lipid nano-environment259
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design254
Biology and therapeutic targeting of vascular endothelial growth factor A254
Curvature-mediated endocytosis248
Mechanisms and roles of podosomes and invadopodia248
The RNA world ‘hypothesis’247
Publisher Correction: Emerging roles and functional mechanisms of PIWI- interacting RNAs244
Big cells, small potential244
Molecular tools for analysing in vivo senescence227
A quick guide to (transmembrane) planar cell polarity mouse strains226
Science Twitter — navigating change in science communication222
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens217
Context-dependent TGFβ family signalling in cell fate regulation206
Splicing regulation through biomolecular condensates and membraneless organelles198
Migrasomes promote angiogenesis198
The prospects and opportunities of protein structure prediction with AI196
Improving chemical reprogramming strategies189
A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals187
Why novel mRNA modifications are so challenging and what we can do about it186
FOXO transcription factors as mediators of stress adaptation183
Circadian clock communication during homeostasis and ageing183
Machinery, regulation and pathophysiological implications of autophagosome maturation182
Molecular mechanisms and consequences of mitochondrial permeability transition178
Transposons: catch them if you can172
New tool for MAPping microtubule dynamics168
RNA binding — a useful third wheel in transcription168
Activation of human endogenous retroviruses and its physiological consequences161
Context-specific regulation and function of mRNA alternative polyadenylation148
Replication stress as a trigger for cell extrusion148
Energy-driven genome regulation by ATP-dependent chromatin remodellers148
Mechanisms of mitochondrial respiratory adaptation148
Does species-specific alternative splicing make us human?146
Integrated biophysical imaging of cell interactions with 3D extracellular matrices143
Revisiting small RNA movement in plants142
Regulation and function of insulin and insulin-like growth factor receptor signalling140
Apical–basal polarity and the control of epithelial form and function135
Transcriptional control of energy metabolism by nuclear receptors132
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases127
A guide to cell death pathways118
Targeted protein degradation: from mechanisms to clinic117
Myosin VI assists in fork protection116
How ancient RNA survives and what we can learn from it116
Cold-induced longevity through proteasome boosting115
A Tour de force of primary cilium biogenesis115
New frontiers in quality control: the case of GPI-anchored proteins114
Resolution in super-resolution microscopy — definition, trade-offs and perspectives111
The centromere as a tag of self-DNA110
Author Correction: All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies109
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex108
The molecular basis for cellular function of intrinsically disordered protein regions107
Molecular mechanisms underlying nucleotide repeat expansion disorders105
The technological landscape and applications of single-cell multi-omics104
DEI conversations: more than a box-ticking exercise103
Polarized endoplasmic reticulum–plasma membrane contacts in cell migration95
Microenvironmental determinants of endothelial cell heterogeneity94
Author Correction: Fibroblast and myofibroblast activation in normal tissue repair and fibrosis91
Fat cells have long-lasting (epigenetic) memory87
Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition86
Genome characteristics at the borders86
ATP and ROS signal cell extrusion84
Deep learning shapes single-cell data analysis83
Author Correction: Regulation of membrane protein structure and function by their lipid nano-environment83
Anticancer effects of zotatifin are mediated by RNA structure remodelling81
Nuclear compartmentalization as a mechanism of quantitative control of gene expression78
Interplay between mechanics and signalling in regulating cell fate78
The role and regulation of integrins in cell migration and invasion78
Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death77
Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases76
Sleep tight thanks to Parp176
Mechanisms of microtubule organization in differentiated animal cells76
RAG-ulating mTORC1 with amino acids74
Ethylene — the lifeguard hormone71
Author Correction: Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics71
Unravelling oocyte ultrastructure70
Voices of the new generation: importance of emotional ‘match’ in mentoring relationships68
From shortening telomeres to replicative crisis67
All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies65
The contribution of databases towards understanding the universe of long non-coding RNAs65
Reassessing the relationship between mRNA levels and protein abundance in exercised skeletal muscles62
Transcription factors crossing the cell membrane59
How green is your science? The race to make laboratories sustainable57
The molecular principles of gene regulation by Polycomb repressive complexes56
Profiling the disordered proteome in cells using a chemical tag56
Karyopherin-mediated nucleocytoplasmic transport55
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis54
Mechanisms of SARS-CoV-2 entry into cells53
Mechanisms and regulation of substrate degradation by the 26S proteasome51
Exercise metabolism and adaptation in skeletal muscle51
The many regulators of epithelial−mesenchymal transition50
EV signalling in the haematopoietic niche50
Cellular role of TETs in early embryos49
Cellular and molecular control of vertebrate somitogenesis48
Translation feedback control in the brain47
Author Correction: The role of the haematopoietic stem cell niche in development and ageing46
Following the electric current45
The senescence-associated secretory phenotype and its physiological and pathological implications45
The birth of evo-devo40
SWI/SNF chromatin remodellers persist through mitosis36
Deciphering ADP-ribosylation signalling36
Calcium connects lysosomal damage to stress granule formation35
Mechanisms and regulation of DNA end resection in the maintenance of genome stability34
The bioethics of synthetic cells34
The bystander effect of pyroptosis33
The principles of directed cell migration29
Keeping oocytes young28
Mediat(or)ing adult stem cells by XIST27
Harnessing fluorescent probes to unveil dynamic membrane mechanics26
Publisher Correction: Generation of nanoscopic membrane curvature for membrane trafficking26
Voices of the new generation: my unconventional way to stay in academia26
ERMES — from myths to molecules26
Spatiotemporal control over cell–matrix interactions using dynamic micropatterns26
ncRNA regulation of mitochondrial transcription24
Proteins that assemble co-translationally lean on their partner for stability24
Signalling mechanisms and cellular functions of SUMO23
Local and systemic mechanisms that control the hair follicle stem cell niche23
Mechanical state transitions in the regulation of tissue form and function23
Present and future of synthetic cell development23
Internal-m7G-modified mRNAs quake under stress22
Author Correction: Molecular mechanisms underlying nucleotide repeat expansion disorders21
Let’s talk about (biological) sex20
Sorting membrane proteins by size in the Golgi20
Lasker Award for AlphaFold20
Smelling your way to longevity20
Epigenetic discovery by enzyme activity profiling20
Blebbisomes are one bleb away from a functional cell19
A nuclear morphology-based machine learning algorithm for senescence detection19
The nuance in DNA and transcription factor interactions19
Early insights into co-translational assembly of protein complexes17
Cracking genetic codes of longevity17
Size matters16
Translating the midbody for cytokinesis15
The birth of stable introns15
Translational control of stem cell function14
Cellular functions of the protein kinase ATM and their relevance to human disease14
Mitochondrial ROS drive cell cycle progression13
Cellular functions of eukaryotic RNA helicases and their links to human diseases12
m6A nuclear condensates support AML12
Control of satellite cell function in muscle regeneration and its disruption in ageing12
New imprinting control-like regions11
The discovery of cyclin-dependent kinases11
5mC: what goes on must come off10
BCL-2 proteins in senescence: beyond a simple target for senolysis?10
Mapping organelle supply chains10
Pioneer factors as master regulators of the epigenome and cell fate10
Mechanisms and regulation of human mitochondrial transcription10
Author Correction: Fundamentals of redox regulation in biology9
Single-cell lipidomics reveals the organizing principle of cell fate decision9
Genome control by SMC complexes9
Viruses show the way9
Mechanistic insights into gasdermin-mediated pyroptosis9
Paleoproteomics sheds light on million-year-old fossils8
Monitoring subcellular protein localization at scale in live cells8
The role of ordered cooperative assembly in biomolecular condensates7
Effects of aneuploidy on cell behaviour and function7
Gene regulation in time and space during X-chromosome inactivation7
Goodbye, senescent cells: CAR-T cells unleashed to fight ageing7
Exploring the uncharted landscape of truncated mRNAs7
Shaping epithelial tissues by stem cell mechanics in development and cancer7
Cell–extracellular matrix mechanotransduction in 3D7
Modes of Notch signalling in development and disease6
The lipotype hypothesis6
Returning to the lab after a career break6
A novel photosystem assembly line worker6
The double-edged sword of bivalency6
oskar stands on solid ground for translation6
The role of the haematopoietic stem cell niche in development and ageing5
Protrusion-derived vesicles: new subtype of EVs?5
Modelling human brain development and disease with organoids5
Principles and dynamics of spindle assembly checkpoint signalling5
Enhancer selectivity in space and time: from enhancer–promoter interactions to promoter activation5
Mechanics and functional consequences of nuclear deformations5
A catalytic function for mammalian Argonautes4
Probing cytoskeletal remodelling by cutting and marking filaments4
How embryos sort themselves out4
BERing transcriptional noise for cell plasticity4
Condensates trail the nucleus4
A histone code controls positional identity in limb regeneration4
Compression as a driver of hair loss4
DNA modifications walk a fine line between epigenetics and mutagenesis4
The prompt to discover senolytics4
The memory of viscosity3
A guide to machine learning for biologists3
Regulation and functions of non-m6A mRNA modifications3
Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer3
Challenges and opportunities in macromolecular structure determination3
Regulation of microtubule dynamics, mechanics and function through the growing tip3
Senescent cells support limb regeneration3
Regulation of and challenges in targeting NAD+ metabolism3
Mechanisms of mechanotransduction and physiological roles of PIEZO channels3
Base editing of organellar DNA with programmable deaminases3
The neuronal epigenome is special3
RNF26 and vimentin orchestrate ER stress recovery3
Genome doubling — twice the same is not the same2
MYC in TOP shape2
Biochemical and mechanical regulation of actin dynamics2
oskar switches motors halfway through its journey2
Control of stem cell renewal and fate by YAP and TAZ2
First demonstration of miRNA-dependent mRNA decay2
Cell cycle control in cancer2
Cell quiescence sends argonaute-2 to transposons2
The cell biology of ferroptosis2
The multiple links between actin and mitochondria2
Slow cell death helps tissue repair2
Neurons whisper, tissues respond: neurons as orchestrators of stress responses2
A code within the genetic code2
RNA polymerase II transcription compartments: from multivalent chromatin binding to liquid droplet formation?2
The discovery of simple repeats that cause complex disorders2
Modelling tauopathies2
Dicing viral RNA in stem cells2
Cytosol-to-nucleus journey of a novel histone PTM2
Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics2
A guide to membraneless organelles and their various roles in gene regulation2
A SOX9 switch from regeneration to fibrosis2
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