Nature Reviews Molecular Cell Biology

Article	Citations
A Tour de force of primary cilium biogenesis	1984
Solving the Wnt nuclear puzzle	962
Epithelia arm up for dead-cell clearance	899
Cytokinin receptor turns 20	824
Sequencing technologies to measure translation in single cells	806
Epigenetic discovery by enzyme activity profiling	762
The centromere as a tag of self-DNA	605
From organism behaviour to molecular mechanisms	536
The translation m(o)TOR that propels regeneration	445
MYC in TOP shape	411
Cold-induced longevity through proteasome boosting	410
Has translation in the nucleus found its purpose?	402
Tau oligomers are linked to m6A-RNA	377
Anoikis resistance through blebs	371
Cell quiescence sends argonaute-2 to transposons	345
Smelling your way to longevity	342
Genome doubling — twice the same is not the same	329
Myosin VI assists in fork protection	328
Regulation of cellular and systemic sphingolipid homeostasis	313
From trans-splicing discovery and onwards, trypanosomes lead the way	306
Chaperoning solid aggregates for autophagy	298
The neuronal epigenome is special	296
The discovery of simple repeats that cause complex disorders	283
Mechanisms of substrate processing during ER-associated protein degradation	277
Tightening the epithelium to control signalling	261

Internal-m7G-modified mRNAs quake under stress	261
Senescent cells support limb regeneration	252
Re-sizing of nuclear pores	248
Die hard: resilient RNAs in the blood	238
RNF26 and vimentin orchestrate ER stress recovery	233
Mechanism of sperm mtDNA elimination	231
New frontiers in quality control: the case of GPI-anchored proteins	222
Targeting viruses in their phase	219
A dynamic culture system that models the intricacy of the mammary gland	219
Identification of metabolic networks by genetic co-essentiality analysis	218
Modelling tauopathies	216
New guidelines for embryo and stem cell research	213
m6A ‘encodes’ a dedicated mRNA decay pathway	212
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization	208
Lasker Award for AlphaFold	207
Transitioning through the continuum of differentiation	198
Mechanisms and functions of protein S-acylation	195
Transfection reflections: fit-for-purpose delivery of nucleic acids	195
Mechanisms underlying spindle assembly and robustness	188
Sorting membrane proteins by size in the Golgi	187
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex	186
Cell cycle control in cancer	181
Long non-coding RNAs: definitions, functions, challenges and recommendations	179
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways	179
Mechanisms and pathology of protein misfolding and aggregation	178
Plant hormone regulation of abiotic stress responses	178
Mechanisms controlling cellular and systemic iron homeostasis	171
Selective motor activation in organelle transport along axons	170
Heterochromatin definition and function	163
The technological landscape and applications of single-cell multi-omics	157
Understanding mechanisms of antioxidant action in health and disease	149
The assembly, regulation and function of the mitochondrial respiratory chain	146
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids	146
The molecular basis for cellular function of intrinsically disordered protein regions	145
The cell biology of ferroptosis	144
Resolution in super-resolution microscopy — definition, trade-offs and perspectives	143
White adipocyte dysfunction and obesity-associated pathologies in humans	143
Dicing viral RNA in stem cells	141
The aetiology and molecular landscape of insulin resistance	141
Biochemical and mechanical regulation of actin dynamics	139
Author Correction: The roles of Polycomb repressive complexes in mammalian development and cancer	135
Publisher Correction: Translating the midbody for cytokinesis	131
Publisher Correction: White adipocyte dysfunction and obesity-associated pathologies in humans	127
Author Correction: Molecular mechanisms underlying nucleotide repeat expansion disorders	127
Modulation of cellular processes by histone and non-histone protein acetylation	124
Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions	123
IL-11 as a master regulator of ageing	119
When senescence generates pluripotent stem cells	115
In memoriam Judy Campisi: spreading cellular senescence	114
Author Correction: All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies	110

Publisher Correction: Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization	109
Molecular mechanisms underlying nucleotide repeat expansion disorders	107
The multiple links between actin and mitochondria	106
Phosphoinositides as membrane organizers	103
Let’s talk about (biological) sex	100
A lncRNA builds a glycolytic metabolon	98
CTCF works better under tension	95
A SOX9 switch from regeneration to fibrosis	95
Cracking genetic codes of longevity	94
Far from the cytoplasmic crowd	91
Phase separation of biomolecules on free-standing planar membranes	90
The nuance in DNA and transcription factor interactions	88
DEI conversations: more than a box-ticking exercise	85
STINGing through the membrane to channel protons	85
Resilience through selective translation	83
RNA-mediated (de)condensation	80
Making more exosomes	77
The birth of stable introns	74
Intermittent fasting is gaining interest fast	73
Decoding the Ca2+ signal for salt tolerance	70
Control of satellite cell function in muscle regeneration and its disruption in ageing	66
Plant and animal small RNA communications between cells and organisms	65
Cellular and molecular mechanisms of skin wound healing	64
Transcriptional networks controlling stromal cell differentiation	64
Fundamentals of redox regulation in biology	58
Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases	57
Structure and growth of plant cell walls	57
Mitochondrial ROS drive cell cycle progression	56
Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics	56
Structural biology and molecular pharmacology of voltage-gated ion channels	56
Miniaturizing Cas	55
Is amyloid-β a friend or foe?	54
Early insights into co-translational assembly of protein complexes	53
Mending broken hearts with the help of epigenetic remodellers	52
ATP and ROS signal cell extrusion	52
The phosphoinositide PI5P inhibits the Hippo pathway effector YAP	52
Cytosol-to-nucleus journey of a novel histone PTM	51
Who did what: changing how science papers are written to detail author contributions	46
Size matters	46
Damaged mitochondria are discarded via migrasomes	44
A code within the genetic code	44
The cellular and functional complexity of thermogenic fat	43
Endocytosis in the context-dependent regulation of individual and collective cell properties	43
New insights into activation and function of the AMPK	42
A guide to membraneless organelles and their various roles in gene regulation	41
The physiology of alternative splicing	40
Genome characteristics at the borders	38
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance	38
Engineering cellular symphonies out of transcriptional noise	37
‘Poisoning’ of the transcriptome by ultraconserved elements	37
Polarized endoplasmic reticulum–plasma membrane contacts in cell migration	37
RNA polymerase II transcription compartments: from multivalent chromatin binding to liquid droplet formation?	37
Localized translation in the embryo	37
Virus–host warfare by PROTACs	36
Cytoskeletal control of early mammalian development	35
Cellular functions of eukaryotic RNA helicases and their links to human diseases	31
Protein N-terminal acetylation is entering the degradation end game	31
First demonstration of miRNA-dependent mRNA decay	31
Spindle positioning and its impact on vertebrate tissue architecture and cell fate	30
Deep learning shapes single-cell data analysis	26
Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death	26
Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition	25
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment	25
Fat cells have long-lasting (epigenetic) memory	25
Author Correction: Regulation of membrane protein structure and function by their lipid nano-environment	23
Publisher Correction: Plant hormone regulation of abiotic stress responses	22
How proteins sense their cellular environment	20
Autophagy and autophagy-related pathways in cancer	20
Cellular functions of the protein kinase ATM and their relevance to human disease	18
The emerging mechanisms and functions of microautophagy	17
Nuclear compartmentalization as a mechanism of quantitative control of gene expression	17
Mechanisms of microtubule organization in differentiated animal cells	17
Translational control of stem cell function	17
Interplay between mechanics and signalling in regulating cell fate	17
Control of stem cell renewal and fate by YAP and TAZ	16
The double-edged sword of eliminating senescent cells	15
Roles of chromatin and genome instability in cellular senescence and their relevance to ageing and related diseases	15
A nuclear morphology-based machine learning algorithm for senescence detection	15
Author Correction: Fibroblast and myofibroblast activation in normal tissue repair and fibrosis	14
Translating the midbody for cytokinesis	14

Mechanism and regulation of kinesin motors	12
The role and regulation of integrins in cell migration and invasion	11
Microenvironmental determinants of endothelial cell heterogeneity	11
Sperm going in circles	10
Slow cell death helps tissue repair	10
Voices of the new generation: establishing yourself as a PI in a competitive field	10
The bacterial social network and beyond	10
Instruction of epigenetic states from DNA sequences	10
Genetic wrinkles in time	9
m6A nuclear condensates support AML	9
Seeing the smallest rotary biomotor	9
Actin(g) in mitochondria inheritance	9
Transcription factors crossing the cell membrane	8
Speckle function for p53	8
oskar switches motors halfway through its journey	8
Ethylene — the lifeguard hormone	8
Sleep tight thanks to Parp1	8
Structural variation in COOLAIR lncRNA driven by cold	8
RPA dynamics at telomeres	7
BCL-2 proteins in senescence: beyond a simple target for senolysis?	7
5mC: what goes on must come off	7
Voices of the new generation: importance of emotional ‘match’ in mentoring relationships	7
Mechanisms of SNARE proteins in membrane fusion	7
The healing role of gasdermin B in IBD	7
Uncovering SARS-CoV-2 kidney tropism	7
New imprinting control-like regions	6
Hypoxia prevents premature ageing in mice	6
Unravelling oocyte ultrastructure	6
From shortening telomeres to replicative crisis	6
The molecular principles of gene regulation by Polycomb repressive complexes	6
Condensing power of Ca2+	6
Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining	6
C-degron mimicry confers E3 ligase selectivity	6
Reassessing the relationship between mRNA levels and protein abundance in exercised skeletal muscles	5
The many regulators of epithelial−mesenchymal transition	5
Single-cell live volume measurements using the fluorescence exclusion method	5
Condensates burst the bridge for transcription	5
Identification of non-coding silencer elements and their regulation of gene expression	5
Seeing transcription in real time	5
Mechanical regulation of early vertebrate embryogenesis	5
Understanding 3D genome organization by multidisciplinary methods	5
Regulation, functions and transmission of bivalent chromatin during mammalian development	5
Bookmarking pluripotency genes	5
Heterochromatin as a balancing act between transcription and gene silencing	4
Long-lived proteomes in healthy ovaries	4
The contribution of databases towards understanding the universe of long non-coding RNAs	4
Mechanisms and roles of podosomes and invadopodia	4
Longevity lost in translation	4
Epithelial–mesenchymal transition in tissue repair and degeneration	4
RAG-ulating mTORC1 with amino acids	4
Imaging DNA double-strand breaks — are we there yet?	4
Cellular origins of dsRNA, their recognition and consequences	4
Amyloids as kinase signalling platforms	4
microRNA communication in plants	4
Studying lysosomal function and dysfunction using LysoIP	4
Forcing MT glutamylation	4
Alternative cycle for citrate	3
Pitfalls in lipid mass spectrometry of mammalian samples — a brief guide for biologists	3
Karyopherin-mediated nucleocytoplasmic transport	3
Cellular and pathological functions of tau	3
How green is your science? The race to make laboratories sustainable	3
Roles and regulation of tRNA-derived small RNAs in animals	3
Mechanisms of assembly and remodelling of the extracellular matrix	3
The discovery of cyclin-dependent kinases	3
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis	2
Publisher Correction: Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases	2
Adherens junctions as molecular regulators of emergent tissue mechanics	2
Mechanisms and regulation of human mitochondrial transcription	2
Pioneer factors as master regulators of the epigenome and cell fate	2
Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics	2
Genome control by SMC complexes	2
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design	2
The biogenesis and regulation of animal microRNAs	2
Mapping organelle supply chains	2
All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies	2
The discovery of oncogene-induced senescence	2
Ageing and rejuvenation of tissue stem cells and their niches	2
Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology	2
Regulation of membrane protein structure and function by their lipid nano-environment	2
Biology and therapeutic targeting of vascular endothelial growth factor A	2
Mechanisms and regulation of protein synthesis in mitochondria	2
Voices of the new generation: open science is good for science (and for you)	2
Author Correction: Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics	2
Telomere function and regulation from mouse models to human ageing and disease	2
Origin, fate and function of extraembryonic tissues during mammalian development	2
Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation	2
Exercise metabolism and adaptation in skeletal muscle	2
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology	2
Patterning of the cell cortex by Rho GTPases	1
Cellular and molecular control of vertebrate somitogenesis	1
mTOR inhibits starvation-induced nuclear export of the proteasome	1
Author Correction: Intracellular mRNA transport and localized translation	1
Restoration of embryonic gene expression patterns in tissue regeneration and disease	1
MYC between transcription and replication	1
There’s more than one way to suppress cGAS	1