OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Reviews Genetics is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Tightening the (neural) net for protein structure prediction	1013
Single-cell expression profiling has its roots in in situ techniques	985
Explaining the male bias in cancers	818
The different faces of transcription factor sensitivity	782
SCOPE-ing out eukaryotic 6mA	709
The evolution of modifier genes	583
Disentangling population structure in marine species	534
Microorganisms as architects of a sustainable future	454
Interrogating epigenetic mechanisms with chemically customized chromatin	425
Harnessing deep learning for population genetic inference	420
Enhancing sustainable development through plant genetics	387
Getting organized with non-coding RNAs	341
Imprinted genes and the manipulation of parenting in mammals	317
The evolution of DNA sequencing with microfluidics	287
Weaponized genomics: potential threats to international and human security	277
Pleiotropy, epistasis and the genetic architecture of quantitative traits	252
Means, mechanisms and consequences of adenine methylation in DNA	244
Genomic insights into conifer evolution	217
Unveiling the expanding protein universe of life	215
Rapid pathogen surveillance: field-ready sequencing solutions	214
The origin of animals and fungi	208
Cis-regulatory elements at cellular resolution	207
Changes in cell-cycle rate drive diverging cell fates	203
The evolutionary foundations of transcriptional regulation in animals	199
RNA polymerase II transcription compartments — from factories to condensates	187

The epithelial–mesenchymal plasticity landscape: principles of design and mechanisms of regulation	181
Progress in toxicogenomics to protect human health	180
Best practices for single-cell analysis across modalities	179
More than a decade of genetic research on the Denisovans	178
Non-retroviral RNA viruses in eukaryotic genomes	169
Harnessing functional annotation to improve the accuracy and transferability of polygenic scores	168
Mapping dosage	165
Investigating spatial gene circuits and gene–phenotype mechanisms with Perturb-FISH	160
Mini-colons unlock tumour development outside the body	159
Genomic landscape of cancer in racially and ethnically diverse populations	158
Genomic transformations of Eurasian hunter-gatherer populations during the last Ice Age	156
CRISPR editing within microbial communities	141
Targeted genome-modification tools and their advanced applications in crop breeding	140
Revealing gene function with statistical inference at single-cell resolution	137
Intrinsically disordered regions as facilitators of the transcription factor target search	136
Layering epigenomic and transcriptomic space	136
Inhibitors of bacterial immune systems: discovery, mechanisms and applications	132
Epigenomes get personal	129
Predicting the effects of multigene perturbations	128
The hidden diversity of tumours	124
Swapping genes within and beyond our bodies	120
Mate choice through a genomic lens	116
Miller spreads and the power of observation	115
Cohesin and CTCF emerge as building blocks of 3D genome structure	113
Single cell–cell communication	113
Simultaneous single-cell sequencing of RNA and DNA at scale with DEFND-seq	112
Redefining cellular reprogramming with advanced genomic technologies	108
From computational models of the splicing code to regulatory mechanisms and therapeutic implications	105
CHIPping away at the genetic aetiology of clonal haematopoiesis	104
Fine-mapping causal variants — why finding ‘the one’ can be futile	99
ADAR1 inhibits ZBP1 activation by endogenous Z-RNA	97
Retrotransposons: still mobile in humans	94
Scrambling the genome in cancer: causes and consequences of complex chromosome rearrangements	91
Clinical use of polygenic risk scores: current status, barriers and future directions	91
The origin and evolution of Wnt signalling	89
Global genomic diversity for All of Us	88
Social shifts in spiders	88
Genomic newborn screening for rare diseases	88
Fitness effects of mutations throughout evolution	85
The final pieces of the human genome	85
Targeting and engineering long non-coding RNAs for cancer therapy	84
Integrating model systems and genomic insights to decipher mechanisms of cancer metastasis	83
The diversification of methods for studying cell–cell interactions and communication	74
Fitness, growth and transmissibility of SARS-CoV-2 genetic variants	73
Why geneticists should care about male infertility	72
High-throughput biochemistry in RNA sequence space: predicting structure and function	71
The potential of mitochondrial genome engineering	71