OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Reviews Genetics is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Abiotic stress responses in plants	962
The biological and clinical significance of emerging SARS-CoV-2 variants	827
Deciphering cell–cell interactions and communication from gene expression	714
Drug delivery systems for RNA therapeutics	588
Human organs-on-chips for disease modelling, drug development and personalized medicine	560
The genetics of obesity: from discovery to biology	539
Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics	517
The epitranscriptome beyond m6A	411
RNA-binding proteins in human genetic disease	410
Histone post-translational modifications — cause and consequence of genome function	396
Methods and applications for single-cell and spatial multi-omics	354
Best practices for single-cell analysis across modalities	289
Testing at scale during the COVID-19 pandemic	280
Molecular mechanisms of transgenerational epigenetic inheritance	251
Prime editing for precise and highly versatile genome manipulation	211
Autophagy genes in biology and disease	197
The emerging landscape of spatial profiling technologies	195
Towards population-scale long-read sequencing	191
The relationship between genome structure and function	189
The epigenetic basis of cellular heterogeneity	184
Measuring biological age using omics data	182
Alternative splicing as a source of phenotypic diversity	178
Molecular and evolutionary processes generating variation in gene expression	172
Gene therapy using haematopoietic stem and progenitor cells	170
Reprogramming the genetic code	166

Transposable elements shape the evolution of mammalian development	164
Enhancer redundancy in development and disease	163
microRNAs in action: biogenesis, function and regulation	154
The influence of evolutionary history on human health and disease	152
Advancing the use of genome-wide association studies for drug repurposing	150
Obtaining genetics insights from deep learning via explainable artificial intelligence	144
Mining genomes to illuminate the specialized chemistry of life	142
Navigating the pitfalls of applying machine learning in genomics	142
A new era in functional genomics screens	134
Biological roles of adenine methylation in RNA	131
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination	126
Genetic load: genomic estimates and applications in non-model animals	122
Host genetics and infectious disease: new tools, insights and translational opportunities	121
Gene drives gaining speed	117
Non-coding RNAs in disease: from mechanisms to therapeutics	114
Making sense of the ageing methylome	113
Primary cilia as dynamic and diverse signalling hubs in development and disease	109
DNA methylation-based predictors of health: applications and statistical considerations	107
Gene regulatory network inference in the era of single-cell multi-omics	104
Clinical cancer genomic profiling	96
Characterizing cis-regulatory elements using single-cell epigenomics	96
Epigenome plasticity in plants	93
Single-cell atlases: shared and tissue-specific cell types across human organs	92
Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic	89
Mechanical regulation of chromatin and transcription	89
Polygenic scores in biomedical research	88
Generation of extracellular morphogen gradients: the case for diffusion	87
Advances and opportunities in malaria population genomics	87
Pharmacogenomics: current status and future perspectives	86
Temporal modelling using single-cell transcriptomics	86
The human genetic epidemiology of COVID-19	84
Probing the dynamic RNA structurome and its functions	83
African genetic diversity and adaptation inform a precision medicine agenda	83
Regulation of pre-mRNA splicing: roles in physiology and disease, and therapeutic prospects	82
Genetic innovations in animal–microbe symbioses	81
Parental nucleosome segregation and the inheritance of cellular identity	81
The roles of microRNAs in mouse development	81
Interplay between chromatin marks in development and disease	79
tRNA dysregulation and disease	79
Genetic engineering of T cells for immunotherapy	79
The spatial organization of transcriptional control	77
Dynamic alternative DNA structures in biology and disease	77
Genetics of circadian rhythms and sleep in human health and disease	77
Genetics of human telomere biology disorders	76
Organization and expression of the mammalian mitochondrial genome	74
Genetics of substance use disorders in the era of big data	73
Spatial biology of cancer evolution	72