OOIR: Observatory of International Research

Papers

(The TQCC of Reproduction is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
A proposed model of a clock that governs the length of human pregnancy	101
Specc1l deficiency leads to abnormal oocyte meiosis and reduced blastocyst development in mouse	100
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway	96
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review	91
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa	77
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro	62
Pregnanolone appearance coincides with the period of implantation following embryonic diapause in the roe deer	61
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	49
Reproductive effects of combined polycystic ovary syndrome model and high-fat diet: tracing inheritance	44
TMEM119 links to ovarian endometriosis progression via MAPK-mediated suppression of ectopic endometrial stromal cell senescence	40
Superovulation-induced changes in murine ovarian perifollicular angiogenesis	37
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation	34
Engineering stress-tolerant mammalian embryos via a functional trehalose transporter	33
Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome	33
High-lipid nutritional environment in different ontogenetic periods induce developmental programming of rat prostate at aging	31
Scientific contributions of Professor Sir Ian Wilmut	29
Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause	29
Fertility Treatment and Preservation Options for Transgender and Gender Diverse People	26
A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle	26
Ca2+ concentrations in mouse sperm mitochondria fluctuate according to the cytosol	26
Species-specific mechanisms of sperm transport: predominant roles of motility in ewes and uterine contractility in mares	25
Murine models of advanced maternal age: a systematic review and meta-analysis	23
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques	23
Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?	23
A scoping review regarding reproductive capacity modulation based on alpha-ketoglutarate supplementation	23

The effects of the activation of TLR2/TLR1 on in vitro angiogenesis in an immortalized ovine luteal endothelial cell line	23
Telomeres and oocyte maturation rate are not reduced by COVID-19 except in severe cases	22
Lipid metabolism abnormalities induced by elevated PCSK9 in polycystic ovary syndrome mice lead to ovarian granulosa cell apoptosis via AMPK and GSK-3β	20
Ram sperm and seminal plasma alter immune transcriptome and cytokine secretion in ovine cervical explants ex vivo	20
The role of angiotensin II and relaxin in vascular adaptation to pregnancy	19
Single-cell transcriptomics reveals cytotrophoblast subtypes and senescence in recurrent spontaneous abortion	19
Glucose metabolism disorder related to follicular fluid exosomal miR-122-5p in cumulus cells of endometriosis patients	19
Functional identification of miR-21-5p from fallopian tubal extracellular vesicles as a promoter of preimplantation embryo viability	19
Ultrastructural cilia defects in multi-ciliated uterine glandular epithelial cells from women with reproductive failure	18
Asialoglycoprotein receptor 1 positively regulates PTGS2-induced inflammatory response in polycystic ovary syndrome via ERK1/2 pathway	18
Molecular functions of Mrhl lncRNA in mouse spermatogenesis	18
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The impact of polycystic ovary syndrome on reproductive health: a narrative review	18
Highly expressed lncRNA H19 in endometriosis promotes aerobic glycolysis and histone lactylation	17
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology	17
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation	17
Protective effects of metformin and vitamin C on diabetes-induced testicular dysfunction	17
Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI	17
Regulation of testosterone synthesis in Leydig cells by ClC-2 chloride channel	16
Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome	16
Pre‑stimulation follicle aspiration enhances ovarian response and oocyte competence via elevated intrafollicular interleukin-17 in dairy cows	16
DCAF13 and RNF114 participate in the regulation of early porcine embryo development	16
Single-cell transcriptomic atlas of ovarian endometriosis patient’s follicular fluid: unraveling novel insights into abnormal follicular development	16
Pregnancy preparation: redistribution of CCR7-positive cells in the rat uterus	16
Novel insight into CD90 mesenchymal stem cell marker in mouse endometrial stroma during embryo implantation	16
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The significance of functional adrenal hyperandrogenism in polycystic ovary syndrome across the lifespan	15
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Mind the gap: a nationwide audit of LGBTQ+ inclusion in fertility care providers in the United Kingdom	15
A maternal ketogenic diet alters oviduct fluid nutrients and embryo histone acetylation in mice	14
Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells	14
mTORC1-dependent suppression of autophagic activity in somatic cell nuclear transfer mouse embryos	14
Memoriam for Professor Asgerally T. Fazleabas	14
Unveiling the formation of the primordial follicle pool in goats: Insights from single-cell omics analysis	14
Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows	14
Exosomal or follicular FNDC3A decreases FOLR1 mRNA abundance and progesterone and lactate synthesis in bovine granulosa cells	13
Monoclonal antibody potentiating gonadotropin activity in vitro and in vivo in male and female rats and in ewes	13
FXR maintains primordial follicle dormancy via regulating FoxO3 expression	13
Characterization of ovarian progenitor cells for their potential to generate steroidogenic theca cells in vitro	13
Investigating ticagrelor in a preclinical pipeline as a novel therapeutic to prevent preterm birth	13
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs	13
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPROSURES ON REPRODUCTION: Adverse impacts of particulate matter air pollution on female and male reproduction	13
The interaction between seminal plasma, sperm, and endometrium in inter- and intra-species breeding in equids	12
Reproductive Ageing: Declining translational capacity as a potential driver for oocyte meiotic instability	12
L-Methionine enhances cryosurvival and antioxidant activity of boar sperm	12
Identification of potential microRNA markers in plasma vesicles for giant panda pregnancy diagnosis	12
miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation	12
Epigallocatechin-3-gallate mitigates postovulatory oocyte aging by reducing oxidative stress and promoting embryonic development	12
Omne vivum ex ovo : the oocyte reprogramming and remodeling activities	11
DUXA is not essential for parthenogenetic blastocyst formation but regulates cell proliferation in porcine embryos	11
PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Postpartum mental health after medically complicated pregnancy	11
Correction to: High dietary fructose induces the senescence of granulosa cells by enhancing O-GlcNAcylation	11
Hedgehog signalling in solitary motile cilia: detection and role of hedgehog factors in sperm functions and in vitro fertilization	11

Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages	11
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	11
METTL3-mediated m6A modification promotes ferroptosis in adenomyosis through GPX4 in a YTHDF1-dependent manner	11
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	11
The explosion of life: lessons from live imaging of ovulation	11
PP1γ1 is unable to substitute for the mammal-specific PP1γ2 isoform to support male fertility and sperm function	11
Cordycepin suppresses steroidogenic acute regulatory protein expression by reducing SP1 in human granulosa-lutein cells	10
Drosophila AK-3, a homolog of human CKMT1B, is essential for spermiogenesis	10
Identification of circular RNAs as regulators and noninvasive biomarkers for placenta accreta spectrum	10
Blockade of T-type Ca2+ channels disrupts mitochondrial function and follicle development by inhibiting the PI3K/AKT pathway	10
Selection for developmental speed skews sex ratios and metabolic profiles in bovine IVP embryos	10
Changes to the reproductive microbiome of the brood pouch during male pregnancy in seahorses (Hippocampus abdominalis)	10
PCSK9 involves in the high-fat diet-induced abnormal testicular function of male mice	10
Reproductive Ageing: Current insights and a potential role of NAD in the reproductive health of aging fathers and their children	10
The effect of vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function	10
Single-cell multiomic analysis reveals methylome and transcriptome deviations following oocyte maturation in vitro	10
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells	10
Male reproductive tract extracellular vesicles display region-specific heterogeneity in mice	9
Melatonin attenuates Drp1-mediated excessive mitochondrial fission through upregulation of SIRT1 in granulosa cells in polycystic ovary syndrome	9
IGFBP7 enhances trophoblast invasion via IGF-1R/c-Jun signaling in unexplained recurrent spontaneous abortion	9
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	9
Deciphering the maternal uterine signals that shape placenta development	9
Toll-like receptor 4 knockout mice are protected against PMOS-like pathogenesis	9
Mitochondrial uncoupling proteins regulate the metabolic function of human Sertoli cells	9
Processes involved in prostaglandin F2alpha autoamplification in heifers	9
SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor	9
Exogenous melatonin ameliorates embryo–maternal cross-talk in early pregnancy in sheep	9
Exosomes of mesenchymal stem cells and PRP restore spermatogenesis in the rat model of non-obstructive azoospermia	9
Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development	9
Special series on reproductive health in transgender and gender-diverse patients	9
Nicotine exposure disrupts placental development via the Notch signaling pathway	9
Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice	9
Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders	9
Sex, puberty, and the gut microbiome	9
Endometrial stromal cells from women with repeated implantation failure display impaired invasion towards trophoblastic spheroids	8
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: Gestational anti-Müllerian hormone and testosterone excess combined with maternal adiposity program for polycystic ovary syndrome	8
Elucidating metformin action on the ovary and fertility in healthy mice	8
Evidence for a novel role of pregnancy-associated glycoproteins in maintenance of the bovine corpus luteum of pregnancy	8
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Impact of developmental exposures to endocrine-disrupting chemicals on pituitary gland reproductive function	8
Species-specific differences in cumulus support during final oocyte maturation in mice and cattle	8
Acknowledgement to reviewers	8
Sperm utilize tumor necrosis factor alpha to shut down a 2-methoxyestradiol nongenomic pathway that accelerates oviductal egg transport in the rat	8
The history of interferon-stimulated genes in pregnant cattle, sheep, and pigs	8
PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Ethnic disparities in hypertensive disorders of pregnancy	8
TRPM4 contribution in mouse uterine contractions	8
Modulatory role of mTOR in trophoblast adaptive response in the early stage of placentation in sheep	8
Uterine fluid extracellular vesicle miR-223-3p as endometrial receptivity biomarker and regulator in implantation	8
Guidelines for quantifying ovarian follicles: every follicle counts	8
Increased plugging latency in cycling epiERα −/− (Esr1 f/− Wnt7a Cre/+ ) mice	8