OOIR: Observatory of International Research

Papers

(The TQCC of Reproduction is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A proposed model of a clock that governs the length of human pregnancy	127
Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review	78
REPRODUCTIVE TOXICOLOGY: Environmental exposures, fetal testis development and function: phthalates and beyond	52
Specc1l deficiency leads to abnormal oocyte meiosis and reduced blastocyst development in mouse	49
Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation	46
Differentiation of fetal sertoli cells in the adult testis	42
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample	40
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway	35
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	32
Manipulating bovine granulosa cell energy metabolism limits inflammation	30
Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells	29
How, where and when is SPINK3 bound and removed from mouse sperm?	27
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa	26
Fertility Treatment and Preservation Options for Transgender and Gender Diverse People	26
High-lipid nutritional environment in different ontogenetic periods induce developmental programming of rat prostate at aging	25
Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome	25
TORC2/3-mediated DUSP1 upregulation is essential for human decidualization	24
Scientific contributions of Professor Sir Ian Wilmut	23
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation	23
Ca2+ concentrations in mouse sperm mitochondria fluctuate according to the cytosol	23
Environmental constraints and pathologies that modulate equine placental genes and development	22
A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle	22
Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause	22
Orphan nuclear receptors in angiogenesis and follicular development	20
CEP164 is essential for efferent duct multiciliogenesis and male fertility	20

Vitamin D in follicular development and oocyte maturation	20
Effect of in vitro growth on mouse oocyte competency, mitochondria and transcriptome	19
Accessory corpus luteum regression during pregnancy II: reproductive outcomes	19
Role of cAMP/PKA/CREB pathway and β-arrestin 1 in LH induced luteolysis in pregnant rats	19
Glucose metabolism disorder related to follicular fluid exosomal miR-122-5p in cumulus cells of endometriosis patients	19
Mitochondrial humanin peptide acts as a cytoprotective factor in granulosa cell survival	19
Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?	18
Murine models of advanced maternal age: a systematic review and meta-analysis	18
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques	18
The role of angiotensin II and relaxin in vascular adaptation to pregnancy	17
A scoping review regarding reproductive capacity modulation based on alpha-ketoglutarate supplementation	16
Two mouse lines selected for large litter size display different lifetime fecundities	16
Organoids as tools to investigate the molecular mechanisms of male infertility and its treatments	16
The effects of the activation of TLR2/TLR1 on in vitro angiogenesis in an immortalized ovine luteal endothelial cell line	16
Cell signaling in sperm midpiece ensures quiescence and survival in cauda epididymis	15
Acbp is essential for decidualization during early pregnancy in mice	15
Telomeres and oocyte maturation rate are not reduced by COVID-19 except in severe cases	15
Ultrastructural cilia defects in multi-ciliated uterine glandular epithelial cells from women with reproductive failure	15
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The impact of polycystic ovary syndrome on reproductive health: a narrative review	15
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells	15
Gadd45g is required for timely Sry expression independently of RSPO1 activity	14
Urocortins exhibit differential effects on PGE2 and PGF2α output via CRHR2 in human myometrium	14
Highly expressed lncRNA H19 in endometriosis promotes aerobic glycolysis and histone lactylation	14
Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI	14
SPERM FACTORS AND EGG ACTIVATION: Fertilization failure after human ICSI and the clinical potential of PLCZ1	13
Pregnancy preparation: redistribution of CCR7-positive cells in the rat uterus	13
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation	13
Molecular functions of Mrhl lncRNA in mouse spermatogenesis	13
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology	13
Novel insight into CD90 mesenchymal stem cell marker in mouse endometrial stroma during embryo implantation	12
The reduction of oocytes and disruption of the meiotic prophase I in Fanconi anemia E-deficient mice	12
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Mind the gap: a nationwide audit of LGBTQ+ inclusion in fertility care providers in the United Kingdom	12
Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells	12
17β-Estradiol and cathepsins control primordial follicle growth in mouse ovaries	11
Mechanisms of ovarian aging	11
DCAF13 and RNF114 participate in the regulation of early porcine embryo development	11
The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesis	11
A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum	11
Extracellular vesicles improve embryo cryotolerance by maintaining the tight junction integrity during blastocoel re-expansion	11
Investigating ticagrelor in a preclinical pipeline as a novel therapeutic to prevent preterm birth	11
Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows	11
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs	10
Involvement of the Linker Histone H1Foo in the Regulation of Oogenesis	10
Aggregation of Leopardus geoffroyi hybrid embryos with domestic cat tetraploid blastomeres	10
T2DM-elicited oxidative stress represses MTA3 expression in mouse Leydig cells	10
Characterization of ovarian progenitor cells for their potential to generate steroidogenic theca cells in vitro	9
Current findings in endometrial microbiome: impact on uterine diseases	9
First mitotic spindle formation is led by sperm centrosome-dependent MTOCs in humans	9
Omne vivum ex ovo: the oocyte reprogramming and remodeling activities	9
Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures	9

Exosomal or follicular FNDC3A decreases FOLR1 mRNA abundance and progesterone and lactate synthesis in bovine granulosa cells	9
miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation	9
Protamines: lessons learned from mouse models	9
Metabolism-driven post-translational modifications of H3K9 in early bovine embryos	9
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPROSURES ON REPRODUCTION: Adverse impacts of particulate matter air pollution on female and male reproduction	9
SPERM FACTORS AND EGG ACTIVATION: PLCzeta as the sperm factor that activates eggs: 20 years on	9
Reproductive Ageing: Declining translational capacity as a potential driver for oocyte meiotic instability	9
A maternal ketogenic diet alters oviduct fluid nutrients and embryo histone acetylation in mice	9
Inflammatory response elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells	9
Vascular biology of uterine fibroids: connecting fibroids and vascular disorders	8
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	8
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	8
The impact of antisperm antibodies on human male reproductive function: an update	8
Dysregulation of intracellular pH is a cause of impaired capacitation in Slc22a14-deficient mice	8
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1	8
The interaction between seminal plasma, sperm, and endometrium in inter- and intra-species breeding in equids	8
Dolly at 25… is she ‘… still goin’ strong?’	8
Identification of circular RNAs as regulators and noninvasive biomarkers for placenta accreta spectrum	8
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages	8
REPRODUCTIVE TOXICOLOGY: Pregnancy exposure to endocrine disrupting chemicals: implications for women’s health	8
Desert hedgehog mediates the proliferation of medaka spermatogonia through Smoothened signaling	8
Drosophila AK-3, a homolog of human CKMT1B, is essential for spermiogenesis	8
Changes to the reproductive microbiome of the brood pouch during male pregnancy in seahorses (Hippocampus abdominalis)	7
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells	7
Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development	7
Reproductive Ageing: Current insights and a potential role of NAD in the reproductive health of aging fathers and their children	7
Processes involved in prostaglandin F2alpha autoamplification in heifers	7
Dysregulation of X-ray repair cross-complementing 4 expression in the eutopic endometrium of women with endometriosis	7
Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders	7
Cordycepin suppresses steroidogenic acute regulatory protein expression by reducing SP1 in human granulosa-lutein cells	7
PP1γ1 is unable to substitute for the mammal-specific PP1γ2 isoform to support male fertility and sperm function	7
PCSK9 involves in the high-fat diet-induced abnormal testicular function of male mice	7
Exogenous melatonin ameliorates embryo–maternal cross-talk in early pregnancy in sheep	7
SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor	7
Heterogeneous spectrum of CFTR gene mutations in Chinese patients with CAVD and the dilemma of genetic blocking strategy	7
The effect of vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function	7
Plasma progesterone secretion during gestation of the captive short-beaked echidna	7
Exosomes of mesenchymal stem cells and PRP restore spermatogenesis in the rat model of non-obstructive azoospermia	7
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	7
Sex, puberty, and the gut microbiome	7
IGFBP7 enhances trophoblast invasion via IGF-1R/c-Jun signaling in unexplained recurrent spontaneous abortion	7
Gankyrin has a potential role in embryo implantation via activation of STAT3	7
Endometrial stromal cells from women with repeated implantation failure display impaired invasion towards trophoblastic spheroids	6
Elucidating metformin action on the ovary and fertility in healthy mice	6
Mitochondrial uncoupling proteins regulate the metabolic function of human Sertoli cells	6
Acknowledgement to reviewers	6
LncRNA LOC102176306 plays important roles in goat testicular development	6
Different regulation of IRE1α and eIF2α pathways by oxygen and insulin in ACH-3P trophoblast model	6
The central role of pyruvate metabolism on the epigenetic maturation and transcriptional profile of bovine oocytes	6
Muscarinic acetylcholine receptor M5 is involved in spermatogenesis through the modification of cell–cell junctions	6
Modulatory role of mTOR in trophoblast adaptive response in the early stage of placentation in sheep	6
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Impact of developmental exposures to endocrine-disrupting chemicals on pituitary gland reproductive function	6
Special series on reproductive health in transgender and gender-diverse patients	6
TRPM4 contribution in mouse uterine contractions	6
GDF-8 stimulates trophoblast cell invasion by inducing ALK5-SMAD2/3-mediated MMP2 expression	6
NSUN5 is essential for proper cell proliferation and differentiation of mouse preimplantation embryos	6
The history of interferon-stimulated genes in pregnant cattle, sheep, and pigs	6
Increased plugging latency in cycling epiERα −/− (Esr1 f/− Wnt7a Cre/+ ) mice	6
Sperm utilize tumor necrosis factor alpha to shut down a 2-methoxyestradiol nongenomic pathway that accelerates oviductal egg transport in the rat	6
Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice	6
Nicotine exposure disrupts placental development via the Notch signaling pathway	6
REPRODUCTIVE TOXICOLOGY: Impacts of paternal environment and lifestyle on maternal health during pregnancy	6
Placental leukocyte infiltration accompanies gestational changes induced by hyperthyroidism	6
Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads	6
Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations	6
Diet-induced- and genetic-obesity differentially alters male germline histones	6