Reproduction

Article	Citations
HYPOXIA AND REPRODUCTIVE HEALTH: Oxygen and development of the human placenta	100
COVID-19 and male reproductive function: a prospective, longitudinal cohort study	96
Mechanisms of ovarian aging	85
Animal models of human pregnancy and placentation: alternatives to the mouse	72
Equine endometritis: a review of challenges and new approaches	64
Evaluating the impact of COVID-19 on male reproduction	57
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis	55
Meiosis interrupted: the genetics of female infertility via meiotic failure	51
Single cell transcriptome research in human placenta	47
Macrophage-derived multinucleated giant cells: hallmarks of the aging ovary	43
PREIMPLANTATION GENETIC TESTING: Non-invasive prenatal testing for aneuploidy, copy-number variants and single-gene disorders	40
HYPOXIA AND REPRODUCTIVE HEALTH: Hypoxia and ovarian function: follicle development, ovulation, oocyte maturation	35
Mass spectrometry reveals distinct proteomic profiles in high- and low-quality stallion spermatozoa	31
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Oxidative stress in polycystic ovary syndrome	29
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Reactive oxygen species in the mammalian pre-implantation embryo	29
Current findings in endometrial microbiome: impact on uterine diseases	29
Derivation of sheep embryonic stem cells under optimized conditions	28
Human sperm tsRNA as potential biomarker and therapy target for male fertility	28
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: The protection of mammalian spermatozoa against oxidative stress	28
HYPOXIA AND REPRODUCTIVE HEALTH: Reproductive challenges at high altitude: fertility, pregnancy and neonatal well-being	27
Vascular biology of uterine fibroids: connecting fibroids and vascular disorders	27
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: The impact of oxidative stress on reproduction: a focus on gametogenesis and fertilization	27
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology	26
Healthy ageing and spermatogenesis	26
HYPOXIA AND REPRODUCTIVE HEALTH: The role of hypoxia in the development and progression of endometriosis	25

FGF2/FGFR signaling promotes cumulus–oocyte complex maturation in vitro	25
Investigation of infertility using endometrial organoids	23
Sperm selection by rheotaxis improves sperm quality and early embryo development	21
Maternal recognition of pregnancy in the mare: does it exist and why do we care?	21
The impact of antisperm antibodies on human male reproductive function: an update	21
Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations	20
PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease risk	19
REPRODUCTIVE TOXICOLOGY: Impact of endocrine disruptors on neurons expressing GnRH or kisspeptin and pituitary gonadotropins	19
Sex, puberty, and the gut microbiome	19
PREIMPLANTATION GENETIC TESTING: Clinical experience of preimplantation genetic testing	18
Mitochondrial regulation in spermatogenesis	18
Homeostatic regulation of lipid droplet content in mammalian oocytes and embryos	18
HYPOXIA AND REPRODUCTIVE HEALTH: The presence and role of hypoxia in the endometrium	18
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Oxidative stress and in vitro ageing of the post-ovulatory oocyte: an update on recent advances in the field	17
Vitamin D in follicular development and oocyte maturation	17
Equine maternal aging affects oocyte lipid content, metabolic function and developmental potential	17
Organoids as tools to investigate the molecular mechanisms of male infertility and its treatments	17
The SLC7A11: sperm mitochondrial function and non-canonical glutamate metabolism	17
Similarities between bovine and human germline development revealed by single-cell RNA sequencing	17
HYPOXIA AND REPRODUCTIVE HEALTH: Hypoxia and labour	17
Melatonin ameliorates ovarian dysfunction by regulating autophagy in PCOS via the PI3K-Akt pathway	17
HYPOXIA AND REPRODUCTIVE HEALTH: Hypoxic regulation of preimplantation embryos: lessons from human embryonic stem cells	15
The transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in mice	15
Molecular interactions at the bovine embryo–endometrial epithelium interface	15
Hormone-responsive organoids from domestic mare and endangered Przewalski’s horse endometrium	15
First mitotic spindle formation is led by sperm centrosome-dependent MTOCs in humans	15
First insights on seminal extracellular vesicles in chickens of contrasted fertility	15
Orphan nuclear receptors in angiogenesis and follicular development	15
Growing human trophoblasts in vitro: a review of the media commonly used in trophoblast cell culture	15
Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation	15
Physical activity throughout pregnancy is key to preventing chronic disease	15
CEP164 is essential for efferent duct multiciliogenesis and male fertility	15
REPRODUCTIVE TOXICOLOGY: Pregnancy exposure to endocrine disrupting chemicals: implications for women’s health	15
Aneuploidy during the onset of mouse embryo development	14
Placental adaptation to maternal malnutrition	14
Decreased Indian hedgehog signaling activates autophagy in endometriosis and adenomyosis	14
Immunological aspects of ovarian follicle ovulation and corpus luteum formation in cattle	14
Ligustrazine-induced microRNA-16-5p inhibition alleviates preeclampsia through IGF-2	13
CLDN1 regulates trophoblast apoptosis and proliferation in preeclampsia	13
A systematic review and standardized clinical validity assessment of genes involved in female reproductive failure	13
REPRODUCTIVE TOXICOLOGY: Effects of chemical mixtures on the ovary	13
Effect of aflatoxin B1 on bovine spermatozoa’s proteome and embryo’s transcriptome	13
Inflammatory response elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells	12
Pro-angiogenic effects of pregnancy-specific glycoproteins in endothelial and extravillous trophoblast cells	12
DOHaD: A MENAGERIE OF ADAPTATIONS AND PERSPECTIVES: Large animal models of developmental programming: sustenance, stress, and sex matter	12
Obesity induction in adult zebrafish leads to negative reproduction and offspring effects	12
In vitro fertilization program in white rhinoceros	12
REPRODUCTIVE TOXICOLOGY: Endocrine disruption and reproductive disorders: impacts on sexually dimorphic neuroendocrine pathways	12
SPERM FACTORS AND EGG ACTIVATION: Phospholipase C zeta (PLCZ1) and the clinical diagnosis of oocyte activation deficiency	12
Irisin and the fibronectin type III domain-containing family: structure, signaling and role in female reproduction	12

Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares	12
Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells	12
Core clock gene Bmal1 deprivation impairs steroidogenesis in mice luteinized follicle cells	11
Effect of in vitro growth on mouse oocyte competency, mitochondria and transcriptome	11
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	11
GDF-8 stimulates trophoblast cell invasion by inducing ALK5-SMAD2/3-mediated MMP2 expression	11
The potential role of the E SRRG pathway in placental dysfunction	11
CRISPR/Cas13d-mediated efficient KDM5B mRNA knockdown in porcine somatic cells and parthenogenetic embryos	11
Implications for preeclampsia: hypoxia-induced Notch promotes trophoblast migration	11
SPERM FACTORS AND EGG ACTIVATION: Fertilization failure after human ICSI and the clinical potential of PLCZ1	11
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1	11
Mesenchymal stem cells induce expansion of regulatory T cells in abortion-prone mice	10
Hyperpolarization induces cytosolic alkalization of mouse sperm flagellum probably through sperm Na+/H+ exchanger	10
Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders	10
Immunomodulation for unexplained recurrent implantation failure: where are we now?	10
Repurposing existing drugs as a therapeutic approach for the prevention of preterm birth	10
Production of extracellular vesicles from equine embryo-derived mesenchymal stromal cells	10
miR-3074-5p/CLN8 pathway regulates decidualization in recurrent miscarriage	10
Plasma progesterone secretion during gestation of the captive short-beaked echidna	10
REPRODUCTIVE TOXICOLOGY: Environmental exposures, fetal testis development and function: phthalates and beyond	10
Protamines: lessons learned from mouse models	10
TCF3 regulates human endometrial stromal cell proliferation and migration in RPL	10
Muscarinic acetylcholine receptor M5 is involved in spermatogenesis through the modification of cell–cell junctions	10
Balanced Notch-Wnt signaling interplay is required for mouse embryo and fetal development	10
The role of stem cells in uterine involution	10
Hyperactivation of dormant primordial follicles in ovarian endometrioma patients	10
Does supplementation with mitochondria improve oocyte competence? A systematic review	9
Obesity induces male mice infertility via oxidative stress, apoptosis, and glycolysis	9
Germ cell nests in adult ovaries and an unusually large ovarian reserve in the naked mole-rat	9
Cells responding to hedgehog signaling contribute to the theca of ovarian follicles	9
REPRODUCTIVE TOXICOLOGY: The male mammary gland: a novel target of endocrine-disrupting chemicals	9
Probiotic Lactobacillus kefiri prevents endotoxin-induced preterm birth and stillbirth in mice	9
HIF1A-induced heme oxygenase 1 promotes the survival of decidual stromal cells against excess heme-mediated oxidative stress	9
RNA m6A modifications in mammalian gametogenesis and pregnancy	9
Gene editing to investigate the role of conceptus factors in the establishment of pregnancy in the pig	9
Epigenetic abnormalities associated with somatic cell nuclear transfer	9
SOCE-inhibitor reduced human sperm-induced formation of neutrophil extracellular traps	9
CXCL12 and its receptors regulate granulosa cell apoptosis in PCOS rats and human KGN tumor cells	9
Genesis of clinical and subclinical endometritis in dairy cows	9
Functional attributes of seminal proteins in bull fertility: a systematic review	8
Obesity alters the ovarian DNA damage response and apoptotic proteins	8
A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle	8
Nicotinamide riboside supplementation ameliorated post-ovulatory oocyte quality decline	8
WISP2/IGF1 promotes the survival of DSCs and impairs the cytotoxicity of decidual NK cells	8
PREIMPLANTATION GENETIC TESTING: Single-cell technologies at the forefront of PGT and embryo research	8
Paradigm shift in frog sperm cryopreservation: reduced role for non-penetrating cryoprotectants	8
Galectin-9 regulates HTR8/SVneo function via JNK signaling	8
Optical coherence microscopy allows for quality assessment of immature mouse oocytes	8
Orlistat reverses intratesticular lactate transport decline and infertility in male obese rats	8
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	8
Metformin attenuates steroidogenesis in ovarian follicles of the broiler breeder hen	8
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Oxidative stress and the long-term storage of horse spermatozoa	8
Follicular free fatty acid metabolic signatures and their effects on oocyte competence in non-obese PCOS patients	8
Expression of IL-1β and implantation serine proteases is required for mouse blastocyst hatching	8
Equine pregnancy-specific glycoprotein CEACAM49 secreted by endometrial cup cells activates TGFB	8
Two mouse lines selected for large litter size display different lifetime fecundities	8
Desert hedgehog mediates the proliferation of medaka spermatogonia through Smoothened signaling	8
Progesterone induces porcine sperm release from oviduct glycans in a proteasome-dependent manner	8
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception	8
Gestational microbiome: metabolic perturbations and developmental programming	8
Increased dietary energy alters follicle dynamics and wave patterns in heifers	8
Contribution of high-fat diet-induced PCSK9 upregulation to a mouse model of PCOS is mediated partly by SREBP2	7
Three-dimensional analysis and in vivo imaging for sperm release and transport in the murine seminiferous tubule	7
The role of angiotensin II and relaxin in vascular adaptation to pregnancy	7
IGFBP7 enhances trophoblast invasion via IGF-1R/c-Jun signaling in unexplained recurrent spontaneous abortion	7
The E-modulus of the oocyte is a non-destructive measure of zona pellucida hardening	7
Intrauterine LPS inhibited arcuate Kiss1 expression, LH pulses, and ovarian function in rats	7
Manipulating bovine granulosa cell energy metabolism limits inflammation	7
Appropriate expression of P57kip2 drives trophoblast fusion via cell cycle arrest	7
Proteomics and metabolomics in cow fertility: a systematic review	7
NLRP3 inflammasome is involved in uterine activation for labor at term and preterm	7
Inhibiting NTRK2 signaling causes endometriotic lesion regression	7
Inhibition of MTOR signaling impairs rat embryo organogenesis by affecting folate availability	7
Endoplasmic reticulum stress promotes endometrial fibrosis through the TGF-β/SMAD pathway	7
Melatonin-MT1 signal is essential for endometrial decidualization	7
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells	7
Oxidative phosphorylation inhibitors inhibit proliferation of endometriosis cells	7
Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?	7
High-fat diet induces an ovulatory defect associated with dysregulated endothelin-2 in mice	7
LINC02190 inhibits the embryo–endometrial attachment by decreasing ITGAD expression	7

Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm	7
Expression and role of resistin on steroid secretion in the porcine corpus luteum	6
Metabolism-driven post-translational modifications of H3K9 in early bovine embryos	6
17β-Estradiol and cathepsins control primordial follicle growth in mouse ovaries	6
Urocortins exhibit differential effects on PGE2 and PGF2α output via CRHR2 in human myometrium	6
Mitochondrial humanin peptide acts as a cytoprotective factor in granulosa cell survival	6
Effect of oocyte vitrification on glucose transport in mouse metaphase II oocytes	6
Culture of vitrified bovine ovarian tissue on agarose gel inserts maintains follicle integrity	6
A field guide to Aurora kinase inhibitors: an oocyte perspective	6
I W Rowlands, Barbara J Weir and the biology of the hystricomorph rodents	6
A positive COX-2/IL-1β loop promotes decidualization by upregulating CD82	6
Gadd45g is required for timely Sry expression independently of RSPO1 activity	6
Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis	6
Current applications of SCNT in advanced breeding and genome editing in livestock	6
TRIM28 maintains genome imprints and regulates development of porcine SCNT embryos	6
Differences in human placental mesenchymal stromal cells may impair vascular function in FGR	6
Syncytialization and prolonged exposure to palmitate impacts BeWo respiration	6
Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures	6
Impact of nicotinamide mononucleotide on transplanted mouse ovarian tissue	6
Avian sperm increase in vitro the release of exosomes from SST-enriched organoids	6
Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos	6
Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis	6
Chronodisruption: effects on reproduction, transgenerational health of offspring and epigenome	5
A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum	5
Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide	5
Hypermethylation of the GRHL2 promoter region is associated with ovarian endometriosis	5
NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy	5
Role of cAMP/PKA/CREB pathway and β-arrestin 1 in LH induced luteolysis in pregnant rats	5
Irisin modulates glucose metabolism and inhibits steroidogenesis in bovine granulosa cells	5
Environmental constraints and pathologies that modulate equine placental genes and development	5
Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach	5
The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice	5
Constitutive LH receptor activity impairs NO-mediated penile smooth muscle relaxation	5
Palmitoylated GLB1L4 transfers via exosomes to maintain sperm function in rat epididymis	5
Sustained ERK1/2 signaling is necessary for follicular rupture during ovulation in mice	5
Molecular functions of Mrhl lncRNA in mouse spermatogenesis	5
Accessory corpus luteum regression during pregnancy II: reproductive outcomes	5
Hypothalamic involvement and the role of progesterone in the NGF-induced LH surge pathway	5
Sire modulates developmental kinetics and transcriptome of the bovine embryo	5
Blastocyst trophectoderm endocytic activation, a marker of adverse developmental programming	5
Negative effects of endocrine disruptor bisphenol A on ovarian granulosa cells and the protective role of folic acid	5
The CASR antagonist NPS2143 induces loss of acrosomal integrity and proteolysis of SPACA1 in boar spermatozoa	5
SPERM FACTORS AND EGG ACTIVATION: PLCzeta as the sperm factor that activates eggs: 20 years on	5
Cross-species comparison of mouse and human preimplantation development with an emphasis on lineage specification	5
Diet-induced- and genetic-obesity differentially alters male germline histones	5
Telomeres and oocyte maturation rate are not reduced by COVID-19 except in severe cases	5
Endothelin 2: a key player in ovulation and fertility	5
Fish sperm cryopreservation using biodegradable containers: New low-cost and environment-friendly methodology	5
Roads to the strategic targeting of ovarian cancer treatment	5
TORC2/3-mediated DUSP1 upregulation is essential for human decidualization	5
Decreased level of Eomes+dCD8+ T cells with altered function might be associated with miscarriage	4
Differentiation of fetal sertoli cells in the adult testis	4
DJ-1 deficiency causes metabolic abnormality in ornidazole-induced asthenozoospermia	4
The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesis	4
Maternal high-fat diet changes DNA methylation in the early embryo by disrupting the TCA cycle intermediary alpha ketoglutarate	4
Early growth response 1 transcription factor is essential for the pathogenic properties of human endometriotic epithelial cells	4
The nuclear receptors SF1 and COUP-TFII cooperate on the Insl3 promoter in Leydig cells	4
Heterogeneous spectrum of CFTR gene mutations in Chinese patients with CAVD and the dilemma of genetic blocking strategy	4
Causative mechanisms and functional correlates of MTT reduction in stallion spermatozoa	4
Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling	4
Formation of fibrin at sites of conceptus adhesion in the ewe	4
Chromatin remodelers HELLS, WDHD1 and BAZ1A are dynamically expressed during mouse spermatogenesis	4
YY1 and RTCB in mouse uterine decidualization and embryo implantation	4
HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype	4
Suprachiasmatic nucleus and vagus nerve trigger preovulatory LH and ovulation	4
Histological and transcriptomic analysis of Fance-deficient PGCs reveal the possible mechanisms of their depletion	4
LncRNA LOC102176306 plays important roles in goat testicular development	4
Differential RA responsiveness among subsets of mouse late progenitor spermatogonia	4
Normotensive rats with PCOS exhibit the hypertensive pattern: focus on oxidative stress	4
Pendimethalin exposure disrupts mitochondrial function and impairs processes related to implantation	4
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	4
An abnormal LPA/LPAR1–NHE1 axis leads to the autophagy deficiency of trophoblast cells in recurrent spontaneous abortion	4
IgG modulation in male mice with reproductive failure after prenatal inflammation	4
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro	4
Extracellular vesicles improve embryo cryotolerance by maintaining the tight junction integrity during blastocoel re-expansion	4
REPRODUCTIVE TOXICOLOGY: Impacts of paternal environment and lifestyle on maternal health during pregnancy	4
EGF promotes human trophoblast cell invasion by downregulating CTGF expression via PI3K/AKT signaling	4
Characterization of bioenergetic and kinematic plasticity of bovine sperm reveals novel and dynamic temporal traits	4
High-throughput phenotypic screening of the human spermatozoon	3
Alterations in egg white-related genes expression in response to hormonal stimulation	3
Sperm binding to ZP2-coated beads improve the efficiency of porcine in vitro fertilisation	3
Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation	3
The dogma of the sterile uterus revisited: does microbial seeding occur during fetal life in humans and animals?	3
Polychaete consumption increased prostaglandin biosynthesis in female Penaeus monodon	3
Low-moderate dietary phytoestrogens transiently disrupt spermatogenesis and the seminal plasma proteome in the ram	3
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	3
PREIMPLANTATION GENETIC TESTING: Chromosome abnormalities in human embryos	3
NR2C2 of macrophages promotes inflammation via NF-κB in LPS-induced orchitis in mice	3
Obstructed uterine venous return: a preventable cause of dysfunctional labor?	3
Synthetic embryos: a new venue in ethical research	3
Xenograft model of heterotopic transplantation of human ovarian cortical tissue and its clinical relevance	3
Visfatin increases the invasive potential of ovarian granulosa tumor spheroids by reprogramming glucose metabolism	3
Scientific and technological approaches to improve SCNT efficiency in farm animals and pets	3
Temporal trends in equine sperm progressive motility: a systematic review and meta-regression	3
Generation of porcine endometrial organoids and their use as a model for enhancing embryonic attachment and elongation	3