OOIR: Observatory of International Research

Papers

(The TQCC of EMBO Reports is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Concerns about academic freedom caused by the Russia–Ukraine War	155
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium	137
LGBTIQ+N	121
SCF ^FBXW7 regulates G2‐M progression through control of CCNL1	113
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	111
lncRNA‐encoded pep‐AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin	110
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	106
UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis	103
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice	101
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	96
The Golgi microtubules regulate single cell durotaxis	94
The mission to ensure continued funding for excellent basic research	88
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	86
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	86
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	82
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	72
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment	68
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration	64
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis	62
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	61
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis	60
Through an ecological lens	60
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	58
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	58
Energetic landscape of polycystin channel gating	51

Sci‐Con	51
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo	51
Striking the right balance between youth and experience	51
Animals do count	51
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	50
pH regulates hematopoietic stem cell potential via polyamines	50
Zika virus alters centrosome organization to suppress the innate immune response	49
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	48
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses	47
Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells	46
PRMT5 links lipid metabolism to contractile function of skeletal muscles	46
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis	45
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation	45
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	44
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster	44
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells	43
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	41
Resting natural killer cell homeostasis relies on tryptophan/NAD⁺ metabolism and HIF‐1α	41
Sequestration of LINE‐1 in cytosolic aggregates by MOV10 restricts retrotransposition	40
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	40
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	40
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand R	39
IL‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation	39
Functions of animal microRNA‐encoded peptides: the race is on!	39
Specific N‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning	38
Introducing quality measures in an academic research consortium	38
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis	38
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres	37
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation	37
Viral diseases and the brain	37
STAT5bis a key effector ofNRG‐1/ERBB4‐mediated myocardial growth	37
A human coronavirus OC43‐derived polypeptide causes neuropathic pain	37
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL‐22 production	37
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation	36
#IchbinHannah and the fight for permanent jobs for postdocs	36
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2	36
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2	36
Autophagy orchestrates the crosstalk between cells and organs	36
DJ‐1 depletion prevents immunoaging in T‐cell compartments	36
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association	35
Malaria parasites release vesicle subpopulations with signatures of different destinations	35
The regulation of human blastoid research	34
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity	34
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance	33
ER ‐phagy: selective autophagy of the endoplasmic reticulum	33
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers	33
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike	33
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner	33
Open reading frame dominance indicates protein‐coding potential of RNAs	32
CACGAACTACCCTAA	32

Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses	32
Inductive prediction in biology	32
Gold mining nature for natural products	32
Constructive correction	31
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood	30
Fish faeces and ocean life	30
Powering on cGAMP mini factories	30
Getting the message right	30
On predictions and laws in biological evolution	30
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration	29
CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation	29
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism	29
A need for recalibrating access and benefit sharing	29
Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation	29
Pericyte stem cells induce Ly6G⁺ cell accumulation and immunotherapy resistance in pancreatic cancer	29
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation	28
TMBIM5 is the Ca ²⁺ /H ⁺ antiporter of mammalian mitochondria	28
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins	28
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by MHC‐II molecules	28
Understanding redundancy and resilience	28
The need for sustainable leadership in academia	27
A virus‐derived microRNA targets immune response genes during SARS‐CoV‐2 infection	27
Learning tricks from old dogs	27
Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence	27
Confusion	27
Evolution of pathogen virulence	27
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H₂O₂ release	27
KIAA1429/VIRMA promotes breast cancer progression by m⁶A‐dependent cytosolic HAS2 stabilization	26
Phosphorylation by casein kinase 2 enhances the interaction between ER‐phagy receptor TEX264 and ATG8 proteins	26
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability	26
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress	26
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging	26
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria	26
Scholars in peril: when being a scientist can land you in jail (or worse)	25
Optogenetic control of YAP cellular localisation and function	25
Bench science	25
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding	25
A plea for the ultimate optimism	25
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation	25
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration	25
ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness	24
Autism therapy at crossroads	24
An ULK1/2‐PXN mechanotransduction pathway suppresses breast cancer cell migration	24
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	24
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	24
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway	24
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1	24
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	24
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth	23
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	23
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	23
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	23
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity	22
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	22
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	22
We can do better	22
Waste management	22
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	22
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	22
Cx43‐mediated sorting of miRNAs into extracellular vesicles	22
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	22
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1	22
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state	22
MAP kinase cascades in plant development and immune signaling	22
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	22
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction	22
USP17 is required for peripheral trafficking of lysosomes	21
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR⁺ neurons	21
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members	21
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation	21
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease	21
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway	21
The mind of a scientist	21
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	21
Two redundant ubiquitin‐dependent pathways of BRCA1 localization to DNA damage sites	21
MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties	21
Combining organotypic tissue culture with light‐sheet microscopy (OTCxLSFM) to study glioma invasion	20
A trashed treasure	20
The perceived decline of “disruptive” science and technology	20
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments	20

The chromatin factorROWcooperates withBEAF‐32 in regulating long‐range inducible genes	20
Lipid and protein content profiling of isolated native autophagic vesicles	20
An RDH‐Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase	20
Keep biology weird	20
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation	20
Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts	20
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice	20
Ethical aspects of GMO regulation in the EU	20
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss	20
Myddosome clustering in IL‐1 receptor signaling regulates the formation of an NF‐kB activating signalosome	19
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing	19
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse	19
The cancer microbiome	19
Once in a lifetime	19
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy	19
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon	19
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP	19
The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties	19
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin	19
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle	19