EMBO Reports

Papers
(The TQCC of EMBO Reports is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Concerns about academic freedom caused by the Russia–Ukraine War163
LGBTIQ+N140
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice123
The Golgi microtubules regulate single cell durotaxis120
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation115
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection113
Global and precise identification of functional miRNA targets in mESCs by integrative analysis110
The mission to ensure continued funding for excellent basic research107
Through an ecological lens106
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis100
SCF FBXW7 regulates G2‐M progression through control of CCNL1 94
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB390
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration90
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK284
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium77
UBAP2L ‐dependent coupling of PLK1 localization and stability during mitosis70
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus64
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair64
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment63
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis62
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis62
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis60
Striking the right balance between youth and experience54
The post‐translational regulation of transcription factor EB (TFEB) in health and disease54
Sci‐Con53
Animals do count52
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo51
Energetic landscape of polycystin channel gating51
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network50
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates50
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation47
Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells47
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses47
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice46
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness46
Sequestration of LINE‐1 in cytosolic aggregates by MOV10 restricts retrotransposition45
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength44
pH regulates hematopoietic stem cell potential via polyamines43
Functions of animal microRNA‐encoded peptides: the race is on!43
PRMT5 links lipid metabolism to contractile function of skeletal muscles41
The DEAD box RNA helicase DDX42 is an intrinsic41
Morphofunctional changes at the active zone during synaptic vesicle exocytosis41
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary 40
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis40
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster40
Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF‐1α40
IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation39
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis39
Zika virus alters centrosome organization to suppress the innate immune response39
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL‐22 production38
Introducing quality measures in an academic research consortium38
Autophagy orchestrates the crosstalk between cells and organs38
A human coronavirus OC43‐derived polypeptide causes neuropathic pain38
STAT5bis a key effector ofNRG‐1/ERBB4‐mediated myocardial growth38
Malaria parasites release vesicle subpopulations with signatures of different destinations37
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation37
ER ‐phagy: selective autophagy of the endoplasmic reticulum37
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association37
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike37
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity36
The regulation of human blastoid research36
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation36
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner36
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers36
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres35
DJ‐1 depletion prevents immunoaging in T‐cell compartments35
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance35
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB234
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK234
Specific N ‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning34
#IchbinHannah and the fight for permanent jobs for postdocs34
A need for recalibrating access and benefit sharing33
On predictions and laws in biological evolution33
Constructive correction32
CACGAACTACCCTAA32
Gold mining nature for natural products32
Getting the message right32
Inductive prediction in biology32
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism31
Fish faeces and ocean life31
Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer31
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood31
CDK9 and PP2A regulate RNA polymerase II30
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration30
Open reading frame dominance indicates protein‐coding potential of RNAs30
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria30
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins30
Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation29
Understanding redundancy and resilience29
Confusion29
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses29
Learning tricks from old dogs29
A virus‐derived microRNA targets immune response genes during SARS‐CoV‐2 infection28
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria28
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress28
Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence28
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging27
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation27
KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization27
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H2O2 release27
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by 27
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability27
Evolution of pathogen virulence27
Scholars in peril: when being a scientist can land you in jail (or worse)26
A plea for the ultimate optimism26
Phosphorylation by casein kinase 2 enhances the interaction between ER‐phagy receptor TEX264 and ATG8 proteins26
ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness26
Bench science26
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation26
Optogenetic control of YAP cellular localisation and function25
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding25
An ULK1/2‐PXN mechanotransduction pathway suppresses breast cancer cell migration25
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration25
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway25
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice24
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth24
MAP kinase cascades in plant development and immune signaling24
Autism therapy at crossroads24
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B24
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX124
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation24
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF123
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state23
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells23
Cx43‐mediated sorting of miRNAs into extracellular vesicles23
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance23
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway23
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc22
The Drosophila mitotic spindle orientation machinery requires activation, not just localization22
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis122
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons22
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells22
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis22
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation22
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation22
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease22
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway22
MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties22
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity22
Waste management22
USP17 is required for peripheral trafficking of lysosomes22
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction22
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members22
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments22
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning22
We can do better22
The mind of a scientist22
The perceived decline of “disruptive” science and technology21
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation21
Keep biology weird21
Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts21
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss20
An RDH‐Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase20
Once in a lifetime20
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon20
Ethical aspects of GMO regulation in the EU20
Lipid and protein content profiling of isolated native autophagic vesicles20
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice20
The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties20
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing20
A trashed treasure20
The chromatin factor ROW cooperates with BEAF ‐32 in regulating long‐range inducible genes20
Combining organotypic tissue culture with light‐sheet microscopy (OTCxLSFM) to study glioma invasion20
The cancer microbiome20
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals20
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