EMBO Reports

Papers
(The TQCC of EMBO Reports is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Through an ecological lens168
UBAP2L ‐dependent coupling of PLK1 localization and stability during mitosis146
The Golgi microtubules regulate single cell durotaxis130
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation123
SCF FBXW7 regulates G2‐M progression thro120
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment119
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair115
Concerns about academic freedom caused by the Russia–Ukraine War112
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice110
LGBTIQ+N108
Global and precise identification of functional miRNA targets in mESCs by integrative analysis99
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ / BU99
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection97
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of M78
METTL3 protects METTL14 from STUB1 ‐mediated degradation to maintai73
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration71
The post‐translational regulation of transcription factor EB ( TFEB ) in health and disease68
The mission to ensure continued funding for excellent basic research68
Functional skewing of TRIM21‐SIRT5 interplay dictates IL ‐1β production in 68
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis63
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis61
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium57
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus56
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary 54
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation53
Somatosensory neurons express specific sets of lincRNAs , and lincRNA CLAP promotes itch sensation53
pH regulates hematopoietic stem cell potential via polyamines53
Resting natural killer cell homeostasis relies on tryptophan/ NAD + metabolism and HIF 51
Tissue‐like environments shape functional interactions of HIV ‐1 with immature dendritic cells51
Energetic landscape of polycystin channel gating49
PRMT5 links lipid metabolism to contractile function of skeletal muscles47
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network47
Striking the right balance between youth and experience47
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates47
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses46
Sci‐Con45
Functions of animal microRNA‐encoded peptides: the race is on!44
Animals do count43
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo42
Sequestration of LINE ‐1 in cytosolic aggregates by MOV10 restricts retrotransposition42
The DEAD box RNA helicase DDX42 is an intrinsic41
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness40
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength40
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster40
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis40
IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation39
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation39
Zika virus alters centrosome organization to suppress the innate immune response39
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis39
Morphofunctional changes at the active zone during synaptic vesicle exocytosis39
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL ‐22 production39
The regulation of human blastoid research38
#IchbinHannah and the fight for permanent jobs for postdocs38
Introducing quality measures in an academic research consortium38
Bipolar‐associated miR ‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB238
Autophagy orchestrates the crosstalk between cells and organs37
FOXM1 network in association with TREM1 suppression regulates NET f37
DJ‐1 depletion prevents immunoaging in T‐cell compartments37
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association37
Malaria parasites release vesicle subpopulations with signatures of different destinations37
A human coronavirus OC43‐derived polypeptide causes neuropathic pain37
STAT5b is a key effector of NRG ‐1/ ERBB4 ‐mediated myocardial grow36
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV ‐2 spike36
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance35
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres35
ER ‐phagy: selective autophagy of the endoplasmic reticulum35
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1 34
The GCN2 / eIF2αK stress kinase regulates PP1 t34
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation34
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK234
Specific N ‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning33
Getting the message right33
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism33
On predictions and laws in biological evolution32
Gold mining nature for natural products32
Constructive correction32
Inductive prediction in biology31
CACGAACTACCCTAA31
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration31
CDK9 and PP2A regulate RNA polymerase II30
Pericyte stem cells induce Ly6G + cell accumulation and immunotherapy resistance in pancreatic cancer30
Understanding redundancy and resilience30
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins30
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses30
Open reading frame dominance indicates protein‐coding potential of RNAs30
Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence29
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria29
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood29
Learning tricks from old dogs29
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria29
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by 29
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability28
Confusion28
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress28
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation28
Phosphorylation by casein kinase 2 enhances the interaction between ER‐phagy receptor TEX264 and ATG8 proteins27
A plea for the ultimate optimism27
Evolution of pathogen virulence27
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging27
Scholars in peril: when being a scientist can land you in jail (or worse)27
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H 2 O 2 relea27
KIAA1429 / VIRMA promotes breast cancer progression by m 27
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration27
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding26
ZBTB2 links p53 deficiency to HIF ‐1‐mediated hypoxia signaling to promote cancer aggressiveness26
Optogenetic control of YAP cellular localisation and function26
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway26
An ULK1 / 2‐PXN mechanotransduction pathway suppresses breast cancer cell migration26
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance26
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation26
Autism therapy at crossroads25
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B25
DNA demethylation fine‐tunes IL ‐2 production during thymic regulatory T cell differentiation25
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc25
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth24
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway24
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state24
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice24
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells24
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcr24
Cx43‐mediated sorting of miRNAs into extracellular vesicles24
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1 /Tip60 complexes to activate 24
MAP kinase cascades in plant development and immune signaling23
MOV10 recruits DCP2 to decap human LINE ‐1 23
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐ RNA<23
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease23
We can do better23
Spns2/ S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis23
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning23
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR + neurons23
The Drosophila mitotic spindle orientation machinery requires activation, not just localization23
USP17 is required for peripheral trafficking of lysosomes22
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity22
Ethical aspects of GMO regulation in the EU22
Waste management22
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis122
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells22
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation22
The mind of a scientist22
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway22
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members22
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction22
The chromatin factor ROW cooperates with BEAF ‐32 in regulating long‐range inducible genes21
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice21
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation21
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments21
An RDH‐Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase21
The perceived decline of “disruptive” science and technology21
Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts21
A trashed treasure21
Keep biology weird21
The CRHR1 / CREB / REST signaling cascade regul20
Adult neural stem cells and neurogenesis are resilient to intermittent fasting20
The cancer microbiome20
hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK20
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle20
Combining organotypic tissue culture with light‐sheet microscopy ( OTCxLSFM ) to study glioma invasion20
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing20
Lipid and protein content profiling of isolated native autophagic vesicles20
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐1920
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R / TLR20
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss20
Once in a lifetime20
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon20
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV20
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