EMBO Reports

Article	Citations
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	147
Super‐resolution microscopy reveals focal organization of ER‐associated Y‐complexes in mitosis	115
High‐resolution structure of native toxin A from Clostridioides difficile	99
IKKβ is required for the formation of the NLRP3 inflammasome	88
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	87
The mission to ensure continued funding for excellent basic research	86
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	82
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	82
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	76
UBR‐1 ubiquitin ligase regulates the balance between GABAergic and glutamatergic signaling	72
SCF FBXW7 regulates G2‐M progression through control of CCNL1	71
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium	71
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice	70
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	69
POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart	68
Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function	66
The nucleolar protein GNL3 prevents resection of stalled replication forks	66
The coordination of spindle‐positioning forces during the asymmetric division of the Caenorhabditis elegans zygote	65
Concerns about academic freedom caused by the Russia–Ukraine War	65
Melanopsin elevates locomotor activity during the wake state of the diurnal zebrafish	65
Single‐cell transcriptomic landscape of cardiac neural crest cell derivatives during development	61
OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP‐mediated microtubule anchoring	60
Cx43‐mediated sorting of miRNAs into extracellular vesicles	57
Identification and characterization of in vitro expanded hematopoietic stem cells	57
MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming	53

Natural probiotics improve heritable sterility	52
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	48
The human touch	48
Working in close quarters: biparental meiosis in the oocyte	47
Cardio‐respiratory and phenotypic rescue of dystrophin/utrophin‐deficient mice by combination therapy	47
Filling an ARHGAP in our knowledge of human brain evolution	47
An ongoing science‐society‐ethics experiment	47
Let's bring games into university classrooms	46
Feasibility and impact of haplogroup matching for mitochondrial replacement treatment	46
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	46
The most unkindest cut	45
Reconsidering editorial consideration	45
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction	45
Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis	45
Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans	44
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation	44
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells	44
The underappreciated art of creating publication‐quality figures	44
The interactomics of academia	43
LGBTIQ+N	43
Mefloquine targets NLRP3 to reduce lipopolysaccharide‐induced systemic inflammation and neural injury	42
Architecture for research	42
eIF4EHP promotes Ldh mRNA translation in and fruit fly adaptation to hypoxia	42
Autism therapy at crossroads	42
COVID‐19 and the gain of function debates	41
MITOL promotes cell survival by degrading Parkin during mitophagy	41
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	40
The four fronts of immunotherapy	39
A CRISPR response to pandemics?	38
Goliath induces inflammation in obese mice by linking fatty acid β‐oxidation to glycolysis	38
mTORC1 activity negatively regulates human hair follicle growth and pigmentation	37
Sox7‐positive endothelial progenitors establish coronary arteries and govern ventricular compaction	37
Histone lysine methyltransferase Pr‐set7/SETD8 promotes neural stem cell reactivation	37
Work life balance?	36
Muscle‐derived exophers promote reproductive fitness	36
Parkin coordinates mitochondrial lipid remodeling to execute mitophagy	36
Glial Hedgehog signalling and lipid metabolism regulate neural stem cell proliferation in Drosophila	35
NeutrobodyPlex—monitoring SARS‐CoV‐2 neutralizing immune responses using nanobodies	35
OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential	35
Regional heterogeneity of astrocyte morphogenesis dictated by the formin protein, Daam2, modifies circuit function	35
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity	35
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	34
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	34
Bioremediation of cyanide‐containing wastes	34
An exon junction complex‐independent function of Barentsz in neuromuscular synapse growth	34
A force balance model for a cell size‐dependent meiotic nuclear oscillation in fission yeast	33
Light disrupts social memory via a retina‐to‐supraoptic nucleus circuit	33
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	33
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	33
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	32

TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment	32
SDGs in new‐media arts for science	32
A20 controls RANK ‐dependent osteoclast formation and bone physiology	32
ABCB‐mediated shootward auxin transport feeds into the root clock	32
COVID‐19 and the opportunities for research	31
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR‐Cas9 screen	31
The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function	31
Are doping tests in sports trustworthy?	30
Branched‐chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast	30
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration	30
UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis	30
HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions	30
ORF3c is expressed in SARS‐CoV‐2‐infected cells and inhibits innate sensing by targeting MAVS	30
Non‐redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression	29
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast	29
PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice	29
RGCC balances self‐renewal and neuronal differentiation of neural stem cells in the developing mammalian neocortex	29
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	29
KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7	29
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	28
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	28
PML‐NB‐dependent type I interferon memory results in a restricted form of HSV latency	28
EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis	28
Biology lessons in times of COVID	28
Deregulations of miR‐1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1	28
Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint	27
DEAD‐box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3‐piRISC	27
Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20	27
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	27
A method to the madness	27
PTP‐MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates	27
Hyperosmotic stress induces 2‐cell‐like cells through ROS and ATR signaling	26
SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway	26
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging	26
Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4	26
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	26
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression	26
Loss of primary cilia promotes inflammation and carcinogenesis	25
Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway	25
CTCF shapes chromatin structure and gene expression in health and disease	25
MAP kinase cascades in plant development and immune signaling	25
A quantitative fluorescence‐based approach to study mitochondrial protein import	25
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	25
Shade‐induced lncRNAPUAR promotes shade response by repressing PHYA expression	25
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis	25
Break‐induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?	25
Myeloid cell‐specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation	25
Specific RNA interactions promote TDP‐43 multivalent phase separation and maintain liquid properties	25
IP6‐stabilised HIV capsids evade cGAS/STING‐mediated host immune sensing	25
Best practices to ensure robust investigation of circular RNAs: pitfalls and tips	24
A gene subset requires CTCF bookmarking during the fast post‐mitotic reactivation of mouse ES cells	24
Snail enhances arginine synthesis by inhibiting ubiquitination‐mediated degradation of ASS1	24
Fusobacterium nucleatum secretes amyloid‐like FadA to enhance pathogenicity	24
A systematic analysis of microtubule‐destabilizing factors during dendrite pruning in Drosophila	24
How physical forces drive the process of helical membrane protein folding	24
lncRNA‐encoded pep‐AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin	24
Through an ecological lens	24
Phosphorylation of myosin A regulates gliding motility and is essential for Plasmodium transmission	23
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases	23
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	23
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis	23
Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism	23
The stress granule protein G3BP1 promotes pre‐condensation of cGAS to allow rapid responses to DNA	22
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	22
DDX60 selectively reduces translation off viral type II internal ribosome entry sites	22
BRD9 is a druggable component of interferon‐stimulated gene expression and antiviral activity	22
POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner	22
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	22
m6A methylation promotes white‐to‐beige fat transition by facilitating Hif1a translation	22
Regulation of cGAS activity by RNA‐modulated phase separation	22
Endothelial cell‐derived oxysterol ablation attenuates experimental autoimmune encephalomyelitis	22
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth	21
piRNA‐ and siRNA‐mediated transcriptional repression in Drosophila , mice, and yeast: new insights and biodiversity	21
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state	21
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1	21
Tissue resilience: lessons from social resilience	21
Remodeling and activation mechanisms of outer arm dyneins revealed by cryo‐EM	21
Toll‐like receptor 4 is activated by platinum and contributes to cisplatin‐induced ototoxicity	21
TRPV1 sustains microglial metabolic reprogramming in Alzheimer's disease	21
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	21

Overlapping roles for PLK1 and aurora A during meiotic centrosome biogenesis in mouse spermatocytes	21
Pseudomonas aeruginosaLecB suppresses immune responses by inhibiting transendothelial migration	20
Legionella‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	20
Mitochondrial F 1 F O ATP synthase determines the local proton motive force at cristae rims	20
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis	20
LncRNA‐PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis	20
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	20
CircHIPK3 sponges miR ‐558 to suppress heparanase expression in bladder cancer cells	20
Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis	20
The Golgi microtubules regulate single cell durotaxis	20
USP3 plays a critical role in the induction of innate immune tolerance	20
A combinatorial panel for flow cytometry‐based isolation of enteric nervous system cells from human intestine	19
Nuclear Dishevelled targets gene regulatory regions and promotes tumor growth	19
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand R	19
PLK1 regulates centrosome migration and spindle dynamics in male mouse meiosis	19
Single‐cell analysis reveals dynamic changes of neural cells in developing human spinal cord	19
The unfolded protein response links tumor aneuploidy to local immune dysregulation	19
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	19
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER‐phagy, and Collagen quality control	19
Undergraduate students in research	18
We can do better	18
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	18
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	18
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation	18
Combined measures	18
In search of El DORAdo	18
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	18
Unexpected gene activation following CRISPR‐Cas9‐mediated genome editing	18
Cost and availability of novel cell and gene therapies	18
Waste management	18
The piano and the pianist	18
Rapid endotheliitis and vascular damage characterize SARS‐CoV‐2 infection in a human lung‐on‐chip model	18
Endophilin A2 regulates B‐cell endocytosis and is required for germinal center and humoral responses	18
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	18
The mind of a scientist	18
Viperin—taken down with a pinch of salt	17
5 suggestions to increase grant application success rates	17
miR‐AB, a miRNA‐based shRNA viral toolkit for multicolor‐barcoded multiplex RNAi at a single‐cell level	17
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	17
The Russian invasion of Ukraine: a humanitarian tragedy and a tragedy for science	17
Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes	17
Striking the right balance between youth and experience	17
Money, power, and mitochondria	17
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses	17
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons	17
Konnichiwa: Japanese scientists and their struggle to speak English	17
Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity	17
Animals do count	17
Sci‐Con	17
A NANOG‐pERK reciprocal regulatory circuit regulates Nanog autoregulation and ERK signaling dynamics	17
Lysosome positioning and mTOR activity in Lowe syndrome	16
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains	16
Male infertility‐associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery	16
Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress	16
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway	16
PRMT5 links lipid metabolism to contractile function of skeletal muscles	16
Ca2+‐independent transmission at the central synapse formed between dorsal root ganglion and dorsal horn neurons	16
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures	16
A genome‐wide association study identifies a transporter for zinc uploading to maize kernels	16
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis	16
Noncoding SNP at rs1663689 represses ADGRG6 via interchromosomal interaction and reduces lung cancer progression	16
The breakthrough paradox	16
Limiting hESC patents in China under a dual‐value perspective	16
XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7	16
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	16
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction	15
The RNA polymerase II subunit Rpb9 activates ATG1 transcript	15
Vitamin C promotes ACE2 degradation and protects against SARS‐CoV‐2 infection	15
Immunity proteins of dual nuclease T6SS effectors function as transcriptional repressors	15
Sequestration of LINE‐1 in cytosolic aggregates by MOV10 restricts retrotransposition	15
Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP‐ deficient lung cancer	15
Stepwise pluripotency transitions in mouse stem cells	15
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons	15
pH regulates hematopoietic stem cell potential via polyamines	15
Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response	15
Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome	15
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	15
The EU’s GM crop conundrum	14
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping	14
A species by any other name would sound as sweet	14
Quaking 5 suppresses TGF‐β‐induced EMT and cell invasion in lung adenocarcinoma	14
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	14
Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival	14
The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant	14
IL‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation	14
Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro‐adipogenic progenitors	14
Reprogramming of glucocorticoid receptor function by hypoxia	14
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	14
Monomeric agonist peptide/MHCII complexes activate T‐cells in an autonomous fashion	14
Putting the brakes on phagocytosis: “don't‐eat‐me” signaling in physiology and disease	14
Two redundant ubiquitin‐dependent pathways of BRCA1 localization to DNA damage sites	14
Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA	14
Zika virus alters centrosome organization to suppress the innate immune response	14
Aurora B‐dependent polarization of the cortical actomyosin network during mitotic exit	14
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish	14