EMBO Reports

Article	Citations
The mission to ensure continued funding for excellent basic research	211
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	153
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis	152
LGBTIQ+N	151
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	141
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	137
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	132
Erratum To: The Golgi microtubules regulate single cell durotaxis	125
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	120
UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis	102
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	88
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	80
Through an ecological lens	78
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	76
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	69
SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination	66
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	66
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis	65
IL‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation	62
Zika virus alters centrosome organization to suppress the innate immune response	59
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	59
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses	56
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	54
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	54
Animals do count	51

Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF‐1α	51
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo	50
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	49
Sequestration of LINE‐1 in cytosolic aggregates by MOV10 restricts retrotransposition	49
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation	48
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster	48
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis	48
Striking the right balance between youth and experience	46
Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells	45
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	44
pH regulates hematopoietic stem cell potential via polyamines	44
PRMT5 links lipid metabolism to contractile function of skeletal muscles	44
Energetic landscape of polycystin channel gating	44
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	44
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells	44
STAT5b is a key effector of NRG‐1/ERBB4‐mediated myocardial growth	43
Autophagy orchestrates the crosstalk between cells and organs	42
The regulation of human blastoid research	42
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2	41
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres	41
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner	41
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association	39
Malaria parasites release vesicle subpopulations with signatures of different destinations	39
Introducing quality measures in an academic research consortium	39
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers	38
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation	38
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL‐22 production	38
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2	38
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike	37
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis	37
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity	37
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood	36
Single cell clonal analysis identifies an AID‐dependent pathway of plasma cell differentiation	36
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism	36
ER‐phagy: selective autophagy of the endoplasmic reticulum	36
CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation	35
Getting the message right	35
Constructive correction	34
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins	34
Inductive prediction in biology	34
Gold mining nature for natural products	34
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses	34
TMBIM5 is the Ca2+/H+ antiporter of mammalian mitochondria	34
Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer	33
Confusion	33
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H2O2 release	33
KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization	32
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability	32
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC‐II molecules	32
Learning tricks from old dogs	32

Evolution of pathogen virulence	32
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation	31
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress	31
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging	31
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding	30
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway	30
ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness	30
Optogenetic control of YAP cellular localisation and function	30
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation	30
Scholars in peril: when being a scientist can land you in jail (or worse)	29
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	29
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1	29
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration	29
A plea for the ultimate optimism	29
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	29
An ULK1/2‐PXN mechanotransduction pathway suppresses breast cancer cell migration	29
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	29
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	28
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	28
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	28
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	28
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	28
Autism therapy at crossroads	28
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	28
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	28
The mind of a scientist	27
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons	27
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	27
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	26
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation	26
The perceived decline of “disruptive” science and technology	26
The chromatin factor ROW cooperates with BEAF‐32 in regulating long‐range inducible genes	26
Combining organotypic tissue culture with light‐sheet microscopy (OTCxLSFM) to study glioma invasion	26
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members	26
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	26
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation	26
Ethical aspects of GMO regulation in the EU	26
We can do better	26
MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties	26
Lipid and protein content profiling of isolated native autophagic vesicles	26
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments	26
Keep biology weird	26
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice	25
A trashed treasure	24
The cancer microbiome	24
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing	24
The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes	24
ALS‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function	24
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole	24
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon	23
The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties	23
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy	23
Once in a lifetime	23
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle	23
The taste of vitamin C in Drosophila	23
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals	22
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19	22
Metabolomics meets systems immunology	22
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV	22
Bioenergetics of early life	22
Co‐evolution within the plant holobiont drives host performance	22
Adult neural stem cells and neurogenesis are resilient to intermittent fasting	22
hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4	22
Myddosome clustering in IL‐1 receptor signaling regulates the formation of an NF‐kB activating signalosome	21
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin	21
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface	21
Trained immunity induced by high‐salt diet impedes stroke recovery	21
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells	21
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP	21
Metabolic routing maintains the unique fatty acid composition of phosphoinositides	21
Impaired activation of transposable elements in SARS‐CoV‐2 infection	21
Threatened forests	20
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis	20
RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells	20
Constricted migration is associated with stable 3D genome structure differences in cancer cells	20
A short history of beer brewing	20
The fate of surplus laboratory animals	20
Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease	20
FTO negatively regulates the cytotoxic activity of natural killer cells	20
Losing bigly	20

Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV‐2 in children	20
The structure of fly Teneurin‐m reveals an asymmetric self‐assembly that allows expansion into zippers	20
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases	20
Scratching the ocean surface	20
Extracellular vesicles from malaria‐infected red blood cells: not all are secreted equal	19
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast	19
UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture	19
A20 controls RANK‐dependent osteoclast formation and bone physiology	19
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin	19
Nsp16 shields SARS–CoV‐2 from efficient MDA5 sensing and IFIT1‐mediated restriction	19
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	18
ABCB‐mediated shootward auxin transport feeds into the root clock	18
Loss of primary cilia promotes inflammation and carcinogenesis	18
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation	18
A quantitative fluorescence‐based approach to study mitochondrial protein import	18
The piano and the pianist	17
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	17
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity	17
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	17
Legionella‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	17
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	17
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration	17
The nucleolar protein GNL3 prevents resection of stalled replication forks	17
Let's bring games into university classrooms	17
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	17
CTCF shapes chromatin structure and gene expression in health and disease	17
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum	17
Reconsidering editorial consideration	17
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	17
Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport	16
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains	16
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease	16
Functional platelet‐derived mitochondria induce the release of human neutrophil microvesicles	16
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing	16
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish	16
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis	16
Intervention	16
Structural insights into the assembly and activation of the IL‐27 signaling complex	16
Stalking the link between reproduction and aging	16
From pollutant to powerhouse	16
SIRT3‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth	16
ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein	15
LRH‐1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance	15
Local and systemic effects of microbiome‐derived metabolites	15
A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis	15
53BP1‐mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling	15
Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL	15
Orchestrating vesicular and nonvesicular membrane dynamics by intrinsically disordered proteins	15
Dissecting the cotranscriptome landscape of plants and their microbiota	15
Late‐termination of pregnancy for medical reasons: when abortion isn’t really by choice	15
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice	15
Presynaptic cGMP sets synaptic strength in the striatum and is important for motor learning	15
O‐GlcNAcylation promotes topoisomerase IIα catalytic activity in breast cancer chemoresistance	15
A CcdB toxin‐derived peptide acts as a broad‐spectrum antibacterial therapeutic in infected mice	15
The cost of living	15
Something new under the sun: caspases promote cell survival under moderate heat stress	15
Open Access for Open Science	15
The plant FYVE domain‐containing protein FREE1 associates with microprocessor components to repress miRNA biogenesis	15
(Free) Creative Commons content on the internet is not so free after all	15
Cognition: from the cosmos down to molecules – and back	14
LINC00493‐encoded microprotein SMIM26 exerts anti‐metastatic activity in renal cell carcinoma	14
TRAPPC1 is essential for the maintenance and differentiation of common myeloid progenitors in mice	14
MIRO‐1 interacts with VDAC‐1 to regulate mitochondrial membrane potential in Caenorhabditis elegans	14
Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions	14
Interferon‐mediated repression of miR‐324‐5p potentiates necroptosis to facilitate antiviral defense	14
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination	14
How to avoid mistakes in science publications	14
The fountain of youth of mitochondrial research	14
Modernising biomedical research: advancing with nonanimal models	14
MARCH5 promotes STING pathway activation by suppressing polymer formation of oxidized STING	14
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium	14
Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells	14
Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans	14
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction	14
Mitigating the ecological collapse of coral reef ecosystems	14
Desert plants to stop desertification	14
The polyA tail facilitates splicing of last introns with weak 3′ splice sites via PABPN1	14
Low hanging fruit for combatting SARS‐CoV‐2?	14
Inhibition of ATM kinase rescues planarian regeneration after lethal radiation	14
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential	14
Antiviral activity of the human endogenous retrovirus‐R envelope protein against SARS‐CoV‐2	13
Jag2b‐Notch3/1b‐mediated neuron‐to‐glia crosstalk controls retinal gliogenesis	13
Asexuality in Drosophila juvenile males is organizational and independent of juvenile hormone	13
Spindle assembly checkpoint insensitivity allows meiosis‐II despite chromosomal defects in aged eggs	13
Calculation of ATP production rates using the Seahorse XF Analyzer	13
Tetraspanner‐based nanodomains modulate BAR domain‐induced membrane curvature	13
Regulation of cohesin‐mediated chromosome folding by PDS5 in mammals	13
The Preprint Club	13
RAB6 and dynein drive post‐Golgi apical transport to prevent neuronal progenitor delamination	13
In viral games, refs go to the replay	13
Science after Brexit: bright spots on the Horizon?	13
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells	12
A force balance model for a cell size‐dependent meiotic nuclear oscillation in fission yeast	12
A gene subset requires CTCF bookmarking during the fast post‐mitotic reactivation of mouse ES cells	12
MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming	12