EMBO Reports

Article	Citations
Concerns about academic freedom caused by the Russia–Ukraine War	163
LGBTIQ+N	140
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice	123
The Golgi microtubules regulate single cell durotaxis	120
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	115
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	113
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	110
The mission to ensure continued funding for excellent basic research	107
Through an ecological lens	106
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	100
SCF FBXW7 regulates G2‐M progression through control of CCNL1	94
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration	90
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	90
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	84
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium	77
UBAP2L ‐dependent coupling of PLK1 localization and stability during mitosis	70
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	64
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	64
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment	63
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis	62
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis	62
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	60
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	54
Striking the right balance between youth and experience	54
Sci‐Con	53

Animals do count	52
Energetic landscape of polycystin channel gating	51
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo	51
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	50
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	50
Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells	47
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses	47
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation	47
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	46
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	46
Sequestration of LINE‐1 in cytosolic aggregates by MOV10 restricts retrotransposition	45
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	44
Functions of animal microRNA‐encoded peptides: the race is on!	43
pH regulates hematopoietic stem cell potential via polyamines	43
The DEAD box RNA helicase DDX42 is an intrinsic	41
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	41
PRMT5 links lipid metabolism to contractile function of skeletal muscles	41
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis	40
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster	40
Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF‐1α	40
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary	40
IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation	39
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis	39
Zika virus alters centrosome organization to suppress the innate immune response	39
Autophagy orchestrates the crosstalk between cells and organs	38
A human coronavirus OC43‐derived polypeptide causes neuropathic pain	38
STAT5bis a key effector ofNRG‐1/ERBB4‐mediated myocardial growth	38
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL‐22 production	38
Introducing quality measures in an academic research consortium	38
ER ‐phagy: selective autophagy of the endoplasmic reticulum	37
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association	37
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike	37
Malaria parasites release vesicle subpopulations with signatures of different destinations	37
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation	37
The regulation of human blastoid research	36
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation	36
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner	36
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers	36
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity	36
DJ‐1 depletion prevents immunoaging in T‐cell compartments	35
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance	35
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres	35
Specific N ‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning	34
#IchbinHannah and the fight for permanent jobs for postdocs	34
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2	34
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2	34
A need for recalibrating access and benefit sharing	33
On predictions and laws in biological evolution	33
Gold mining nature for natural products	32
Getting the message right	32

Inductive prediction in biology	32
Constructive correction	32
CACGAACTACCCTAA	32
Fish faeces and ocean life	31
Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer	31
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood	31
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism	31
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration	30
Open reading frame dominance indicates protein‐coding potential of RNAs	30
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria	30
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins	30
CDK9 and PP2A regulate RNA polymerase II	30
Confusion	29
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses	29
Learning tricks from old dogs	29
Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation	29
Understanding redundancy and resilience	29
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress	28
Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence	28
A virus‐derived microRNA targets immune response genes during SARS‐CoV‐2 infection	28
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria	28
KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization	27
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H2O2 release	27
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by	27
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability	27
Evolution of pathogen virulence	27
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging	27
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation	27
A plea for the ultimate optimism	26
Phosphorylation by casein kinase 2 enhances the interaction between ER‐phagy receptor TEX264 and ATG8 proteins	26
ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness	26
Bench science	26
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation	26
Scholars in peril: when being a scientist can land you in jail (or worse)	26
Optogenetic control of YAP cellular localisation and function	25
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding	25
An ULK1/2‐PXN mechanotransduction pathway suppresses breast cancer cell migration	25
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration	25
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway	25
MAP kinase cascades in plant development and immune signaling	24
Autism therapy at crossroads	24
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	24
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	24
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	24
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	24
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth	24
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	23
Cx43‐mediated sorting of miRNAs into extracellular vesicles	23
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	23
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	23
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1	23
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state	23
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	22
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	22
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation	22
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	22
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease	22
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway	22
MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties	22
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity	22
Waste management	22
USP17 is required for peripheral trafficking of lysosomes	22
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction	22
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members	22
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments	22
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	22
We can do better	22
The mind of a scientist	22
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	22
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	22
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1	22
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons	22
Keep biology weird	21
Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts	21
The perceived decline of “disruptive” science and technology	21
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation	21
Ethical aspects of GMO regulation in the EU	20
Lipid and protein content profiling of isolated native autophagic vesicles	20
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice	20
The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties	20

Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing	20
A trashed treasure	20
The chromatin factor ROW cooperates with BEAF ‐32 in regulating long‐range inducible genes	20
Combining organotypic tissue culture with light‐sheet microscopy (OTCxLSFM) to study glioma invasion	20
The cancer microbiome	20
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals	20
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss	20
An RDH‐Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase	20
Once in a lifetime	20
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon	20
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy	19
Adult neural stem cells and neurogenesis are resilient to intermittent fasting	19
The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes	19
Myddosome clustering in IL ‐1 receptor signaling regulates the formation of an NF‐kB activating si	19
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole	19
hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4	19
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse	19
Co‐evolution within the plant holobiont drives host performance	19
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin	19
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle	19
Plasmodium sporozoite disintegration during skin passage limits malaria parasite transmission	19
ALS ‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function	19
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV	19
The taste of vitamin C inDrosophila	18
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface	18
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP	18
Metabolomics meets systems immunology	18
Metabolic routing maintains the unique fatty acid composition of phosphoinositides	18
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19	18
RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells	18
Bioenergetics of early life	18
Scratching the ocean surface	17
FTO negatively regulates the cytotoxic activity of natural killer cells	17
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases	17
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells	17
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis	17
Lamarck redux and other false arguments against SARS‐CoV‐2 vaccination	17
Trained immunity induced by high‐salt diet impedes stroke recovery	17
Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor	17
Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody	17
Constricted migration is associated with stable 3D genome structure differences in cancer cells	17
Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins	17
Losing bigly	17
Centrosome linker protein C‐Nap1 maintains stem cells in mouse testes	17
Impaired activation of transposable elements in SARS‐CoV ‐2 infection	17
Nutrition, metabolism, and epigenetics: pathways of circadian reprogramming	17
A short history of beer brewing	17
The structure of fly Teneurin‐m reveals an asymmetric self‐assembly that allows expansion into zippers	16
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia	16
Time for change in research careers	16
GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes	16
Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease	16
The international of wisdom	16
Nsp16 shields SARS–CoV ‐2 from efficient MDA5 sensing and IFIT1 ‐mediated restriction	16
The fate of surplus laboratory animals	16
Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV ‐2 in children	16
Threatened forests	16
Extracellular vesicles from malaria‐infected red blood cells: not all are secreted equal	16
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors	16
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin	16
A20 controls RANK ‐dependent osteoclast formation and bone physiology	15
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	15
Let's bring games into university classrooms	15
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	15
A quantitative fluorescence‐based approach to study mitochondrial protein import	15
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	15
Architecture for research	15
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	15
Reconsidering editorial consideration	15
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R	15
The nucleolar protein GNL3 prevents resection of stalled replication forks	15
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging	15
UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture	15
Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint	15
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation	15
Legionella ‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	15
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in ye	15
ABCB‐mediated shootward auxin transport feeds into the root clock	14
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	14
Pseudomonas aeruginosaLecB suppresses immune responses by inhibiting transendothelial migration	14
SIRT3‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth	14
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish	14
CTCF shapes chromatin structure and gene expression in health and disease	14
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	14
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum	14
Something new under the sun: caspases promote cell survival under moderate heat stress	14
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease	14
Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport	14
Loss of primary cilia promotes inflammation and carcinogenesis	14
Stalking the link between reproduction and aging	14
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing	14
HP1 maintains protein stability of H3K9 methyltransferases and demethylases	14
I was born this way	14
Structural insights into the assembly and activation of the IL‐27 signaling complex	14
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains	14