EMBO Reports

Article	Citations
The mission to ensure continued funding for excellent basic research	239
LGBTIQ+N	173
UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis	149
Erratum To: The Golgi microtubules regulate single cell durotaxis	149
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	147
SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination	143
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	129
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	121
Through an ecological lens	98
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	85
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	82
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	73
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	72
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	70
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis	70
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	68
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis	63
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	62
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	55
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	55
Tissue‐like environments shape functional interactions of HIV‐1 with immature dendritic cells	54
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	54
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	54
Energetic landscape of polycystin channel gating	53
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells	52

Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF‐1α	51
Striking the right balance between youth and experience	51
PRMT5 links lipid metabolism to contractile function of skeletal muscles	48
pH regulates hematopoietic stem cell potential via polyamines	48
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation	48
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses	47
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	47
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo	46
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity	44
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner	43
Single cell clonal analysis identifies an AID‐dependent pathway of plasma cell differentiation	42
The regulation of human blastoid research	42
Autophagy orchestrates the crosstalk between cells and organs	42
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL‐22 production	41
STAT5b is a key effector of NRG‐1/ERBB4‐mediated myocardial growth	40
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres	39
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2	39
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2	39
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike	39
Getting the message right	38
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood	38
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism	38
TMBIM5 is the Ca2+/H+ antiporter of mammalian mitochondria	37
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses	37
CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation	37
Constructive correction	37
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins	36
Learning tricks from old dogs	36
Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer	36
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC‐II molecules	36
Confusion	36
Evolution of pathogen virulence	36
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation	35
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability	35
KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization	35
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging	34
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress	34
ZBTB2 links p53 deficiency to HIF‐1‐mediated hypoxia signaling to promote cancer aggressiveness	33
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H2O2 release	33
A plea for the ultimate optimism	33
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding	33
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration	32
Scholars in peril: when being a scientist can land you in jail (or worse)	32
Autism therapy at crossroads	31
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway	31
An ULK1/2‐PXN mechanotransduction pathway suppresses breast cancer cell migration	31
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	31
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	30
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	30
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	30

MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties	30
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	30
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	30
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	30
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons	30
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	30
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	29
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	29
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐RNA processing during ribosome formation	29
The mind of a scientist	29
We can do better	29
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members	29
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	28
Lipid and protein content profiling of isolated native autophagic vesicles	28
Keep biology weird	27
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation	27
The chromatin factor ROW cooperates with BEAF‐32 in regulating long‐range inducible genes	27
Combining organotypic tissue culture with light‐sheet microscopy (OTCxLSFM) to study glioma invasion	27
The perceived decline of “disruptive” science and technology	27
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments	27
A trashed treasure	26
The taste of vitamin C in Drosophila	26
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19	26
The cancer microbiome	26
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice	26
The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties	26
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy	26
Once in a lifetime	26
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals	25
Adult neural stem cells and neurogenesis are resilient to intermittent fasting	25
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV	25
Metabolomics meets systems immunology	24
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon	24
Co‐evolution within the plant holobiont drives host performance	24
The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes	24
Myddosome clustering in IL‐1 receptor signaling regulates the formation of an NF‐kB activating signalosome	24
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin	24
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle	24
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole	24
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing	24
Impaired activation of transposable elements in SARS‐CoV‐2 infection	23
FTO negatively regulates the cytotoxic activity of natural killer cells	23
Scratching the ocean surface	22
Trained immunity induced by high‐salt diet impedes stroke recovery	22
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases	22
RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells	22
Constricted migration is associated with stable 3D genome structure differences in cancer cells	22
Losing bigly	22
A short history of beer brewing	22
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface	22
Nsp16 shields SARS–CoV‐2 from efficient MDA5 sensing and IFIT1‐mediated restriction	21
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin	21
UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture	21
Legionella‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	21
Threatened forests	21
The structure of fly Teneurin‐m reveals an asymmetric self‐assembly that allows expansion into zippers	21
Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease	21
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis	21
Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV‐2 in children	21
The fate of surplus laboratory animals	21
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	20
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	20
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	20
Reconsidering editorial consideration	20
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast	20
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation	20
A quantitative fluorescence‐based approach to study mitochondrial protein import	20
Let's bring games into university classrooms	20
The nucleolar protein GNL3 prevents resection of stalled replication forks	19
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	19
CTCF shapes chromatin structure and gene expression in health and disease	19
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity	19
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	19
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	19
A20 controls RANK‐dependent osteoclast formation and bone physiology	18
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum	18
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration	18
Structural insights into the assembly and activation of the IL‐27 signaling complex	18
Loss of primary cilia promotes inflammation and carcinogenesis	18
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains	18

ABCB‐mediated shootward auxin transport feeds into the root clock	18
Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport	18
The piano and the pianist	18
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish	18
Stalking the link between reproduction and aging	17
SIRT3‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth	17
Open Access for Open Science	17
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis	17
From pollutant to powerhouse	17
Functional platelet‐derived mitochondria induce the release of human neutrophil microvesicles	17
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease	17
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing	17
Something new under the sun: caspases promote cell survival under moderate heat stress	17
Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans	16
A CcdB toxin‐derived peptide acts as a broad‐spectrum antibacterial therapeutic in infected mice	16
Dissecting the cotranscriptome landscape of plants and their microbiota	16
LINC00493‐encoded microprotein SMIM26 exerts anti‐metastatic activity in renal cell carcinoma	16
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction	16
Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL	16
Mitigating the ecological collapse of coral reef ecosystems	16
Intervention	16
ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein	16
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice	16
Cognition: from the cosmos down to molecules – and back	16
Orchestrating vesicular and nonvesicular membrane dynamics by intrinsically disordered proteins	16
The plant FYVE domain‐containing protein FREE1 associates with microprocessor components to repress miRNA biogenesis	16
The cost of living	16
(Free) Creative Commons content on the internet is not so free after all	16
Local and systemic effects of microbiome‐derived metabolites	16
How to avoid mistakes in science publications	16
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium	15
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential	15
Low hanging fruit for combatting SARS‐CoV‐2?	15
Calculation of ATP production rates using the Seahorse XF Analyzer	15
The polyA tail facilitates splicing of last introns with weak 3′ splice sites via PABPN1	15
Antiviral activity of the human endogenous retrovirus‐R envelope protein against SARS‐CoV‐2	15
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination	15
The fountain of youth of mitochondrial research	15
MARCH5 promotes STING pathway activation by suppressing polymer formation of oxidized STING	15
Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions	15
MIRO‐1 interacts with VDAC‐1 to regulate mitochondrial membrane potential in Caenorhabditis elegans	15
Modernising biomedical research: advancing with nonanimal models	15
O‐GlcNAcylation promotes topoisomerase IIα catalytic activity in breast cancer chemoresistance	15
Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells	15
Inhibition of ATM kinase rescues planarian regeneration after lethal radiation	15
Desert plants to stop desertification	15
TRAPPC1 is essential for the maintenance and differentiation of common myeloid progenitors in mice	15
Jag2b‐Notch3/1b‐mediated neuron‐to‐glia crosstalk controls retinal gliogenesis	14
Science after Brexit: bright spots on the Horizon?	14
SIRT2 negatively regulates the cGAS‐STING pathway by deacetylating G3BP1	14
Regulation of cohesin‐mediated chromosome folding by PDS5 in mammals	14
eIF4EHP promotes Ldh mRNA translation in and fruit fly adaptation to hypoxia	14
The Preprint Club	14
Asexuality in Drosophila juvenile males is organizational and independent of juvenile hormone	14
Spindle assembly checkpoint insensitivity allows meiosis‐II despite chromosomal defects in aged eggs	14
Deregulations of miR‐1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1	14
The four fronts of immunotherapy	14
In viral games, refs go to the replay	14
RAB6 and dynein drive post‐Golgi apical transport to prevent neuronal progenitor delamination	14
An ATG12‐ATG5‐TECPR1 E3‐like complex regulates unconventional LC3 lipidation at damaged lysosomes	14
Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis	14
Tetraspanner‐based nanodomains modulate BAR domain‐induced membrane curvature	14
A force balance model for a cell size‐dependent meiotic nuclear oscillation in fission yeast	13
Erratum To: LncRNA‐PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis	13
Hyperosmotic stress induces 2‐cell‐like cells through ROS and ATR signaling	13
MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming	13
Filling an ARHGAP in our knowledge of human brain evolution	13
A gene subset requires CTCF bookmarking during the fast post‐mitotic reactivation of mouse ES cells	13
mTORC1 activity negatively regulates human hair follicle growth and pigmentation	13
POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart	13
Erratum To: CircHIPK3 sponges miR‐558 to suppress heparanase expression in bladder cancer cells	13
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells	13
Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism	13