OOIR: Observatory of International Research

Papers

(The TQCC of Nature Cell Biology is 93. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)

Article	Citations
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication	1719
Cellular functions of long noncoding RNAs	779
Super-resolution microscopy demystified	566
mTOR as a central hub of nutrient signalling and cell growth	541
The lysosome as a cellular centre for signalling, metabolism and quality control	440
Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells	353
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization	353
The dynamic nature of senescence in cancer	310
ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway	303
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models	297
Integrin activation by talin, kindlin and mechanical forces	287
Non-redundant functions of EMT transcription factors	286
Intergenerational and transgenerational epigenetic inheritance in animals	284
Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells	255
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs	249
Advances in genome editing through control of DNA repair pathways	205
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening	204
Integrin trafficking in cells and tissues	192
Establishment of porcine and human expanded potential stem cells	181
RNA modifications regulating cell fate in cancer	178
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis	177
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors	174
Stem cell dynamics, migration and plasticity during wound healing	169
Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression	168
NAD+ metabolism governs the proinflammatory senescence-associated secretome	168
Metabolism as a guiding force for immunity	157
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy	152
The cell cycle in stem cell proliferation, pluripotency and differentiation	151
Mesenchymal–epithelial transition in development and reprogramming	134
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C	133
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms	132
Bone vascular niche E-selectin induces mesenchymal–epithelial transition and Wnt activation in cancer cells to promote bone metastasis	130
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics	129
Multicolour single-molecule tracking of mRNA interactions with RNP granules	123
Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation	121
Advances in stem cell research and therapeutic development	118
A chromosome folding intermediate at the condensin-to-cohesin transition during telophase	116
Chromatin regulatory mechanisms and therapeutic opportunities in cancer	112
Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme	111
H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids	111
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies	109
Microtubules gate tau condensation to spatially regulate microtubule functions	109
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression	107
A Tppp3+Pdgfra+ tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis	107
Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes	105
The diverse consequences of aneuploidy	101
Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma	101
A chromatin integration labelling method enables epigenomic profiling with lower input	101
Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP	98
Fluidization-mediated tissue spreading by mitotic cell rounding and non-canonical Wnt signalling	96
A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool	95
HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity	95
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response	95
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking	94
Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms	94
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks	93