Nature Cell Biology

(The TQCC of Nature Cell Biology is 93. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication1719
Cellular functions of long noncoding RNAs779
Super-resolution microscopy demystified566
mTOR as a central hub of nutrient signalling and cell growth541
The lysosome as a cellular centre for signalling, metabolism and quality control440
Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells353
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization353
The dynamic nature of senescence in cancer310
ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway303
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models297
Integrin activation by talin, kindlin and mechanical forces287
Non-redundant functions of EMT transcription factors286
Intergenerational and transgenerational epigenetic inheritance in animals284
Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells255
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs249
Advances in genome editing through control of DNA repair pathways205
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening204
Integrin trafficking in cells and tissues192
Establishment of porcine and human expanded potential stem cells181
RNA modifications regulating cell fate in cancer178
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis177
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors174
Stem cell dynamics, migration and plasticity during wound healing169
Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression168
NAD+ metabolism governs the proinflammatory senescence-associated secretome168
Metabolism as a guiding force for immunity157
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy152
The cell cycle in stem cell proliferation, pluripotency and differentiation151
Mesenchymal–epithelial transition in development and reprogramming134
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C133
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms132
Bone vascular niche E-selectin induces mesenchymal–epithelial transition and Wnt activation in cancer cells to promote bone metastasis130
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics129
Multicolour single-molecule tracking of mRNA interactions with RNP granules123
Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation121
Advances in stem cell research and therapeutic development118
A chromosome folding intermediate at the condensin-to-cohesin transition during telophase116
Chromatin regulatory mechanisms and therapeutic opportunities in cancer112
Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme111
H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids111
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies109
Microtubules gate tau condensation to spatially regulate microtubule functions109
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression107
A Tppp3+Pdgfra+ tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis107
Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes105
The diverse consequences of aneuploidy101
Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma101
A chromatin integration labelling method enables epigenomic profiling with lower input101
Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP98
Fluidization-mediated tissue spreading by mitotic cell rounding and non-canonical Wnt signalling96
A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool95
HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity95
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response95
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking94
Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms94
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks93