OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis	438
Telomere dysfunction in ageing and age-related diseases	291
PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis	262
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker	261
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression	248
CRISPR technologies for precise epigenome editing	245
Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling	214
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets	208
Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity	184
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis	169
ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration	144
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	138
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control	136
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells	135
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration	130
Evaluating totipotency using criteria of increasing stringency	127
Liquid-like protein interactions catalyse assembly of endocytic vesicles	123
A single-cell transcriptomic landscape of the lungs of patients with COVID-19	122
Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity	119
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression	114
R-loops as Janus-faced modulators of DNA repair	113
Metabolic communication in the tumour–immune microenvironment	113
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA	112
The STING phase-separator suppresses innate immune signalling	111
A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis	111

Autophagosome biogenesis comes out of the black box	110
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation	109
Generic nature of the condensed states of proteins	108
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age	106
Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses	106
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	104
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells	102
Phase separation of SERRATE drives dicing body assembly and promotes miRNA processing in Arabidopsis	102
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy	99
Depletion of aneuploid cells in human embryos and gastruloids	98
Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress	96
The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W	93
m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype	93
Membrane surfaces regulate assembly of ribonucleoprotein condensates	91
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance	91
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses	90
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer	89
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin	89
Exploring the expanding universe of small RNAs	89
Mechanical force application to the nucleus regulates nucleocytoplasmic transport	86
METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumourigenesis	81
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling	81
TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis	81
Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock	81
Cell type ontologies of the Human Cell Atlas	80
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	78
Anatomical structures, cell types and biomarkers of the Human Reference Atlas	75
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression	75
Control of endothelial quiescence by FOXO-regulated metabolites	74
Stiff matrix induces exosome secretion to promote tumour growth	73
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung	72
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development	72
Single-cell epigenomic landscape of peripheral immune cells reveals establishment of trained immunity in individuals convalescing from COVID-19	71
POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis	70
Proteotoxic stress is a driver of the loser status and cell competition	69
Human melanocyte development and melanoma dedifferentiation at single-cell resolution	69
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition	69
Spatial organization of transcribed eukaryotic genes	68
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis	68
Nucleotide imbalance decouples cell growth from cell proliferation	67
Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning	67
Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia	67