OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	971
Keeping membraneless organelles apart	364
tRNA flux and consistency in differentiation	358
COPIng with senescence	302
Restoring placental methylome	233
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	230
Finding a chaperone for TDP-43	218
Dynein upsizes under load	202
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	191
The guinea pig serves as an alternative model to study human preimplantation development	190
Criteria for the standardization of stem-cell-based embryo models	183
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	181
SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis	179
Designing protein-based artificial kinetochores as decoys to prevent meiotic errors in oocytes	170
Reinvigorating COTL1high NK cells via GITR signalling overcomes immune checkpoint blockade resistance in tsMHC-I-impaired tumours	170
Ectosomes step forward in α-synuclein spread	164
Atlas of amnion development during the first trimester of human pregnancy	163
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	158
ER-associated RNA silencing promotes ER quality control	158
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	147
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	146
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	145
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	138
How a ribosomal protein avoids mixed signals	136
A guideline on the molecular ecosystem regulating ferroptosis	136

A serendipitous discovery of a family of membrane remodelling proteins	133
Regenerating the academic pipeline	133
Implementing sustainable science in the lab	132
PRC2 shields the potency of human stem cells	131
HSF1 renders NK cells too stressed to respond	130
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	128
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	126
Nuclear class 3 PI3K coactivates circadian clock	124
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	123
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death	123
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	116
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	114
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	110
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis	105
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	105
Acidic niche sugar shield blocks ferroptosis	100
Real-time and programmable transcriptome sequencing with PROFIT-seq	94
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	92
Mitoxyperilysis as a distinct cell death type	91
Mechanisms and functions of large extracellular vesicle biogenesis	90
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	89
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	89
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	88
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	87
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	87
A lysosomal surveillance response to stress extends healthspan	86
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	85
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	84
Spermidine is essential for fasting-mediated autophagy and longevity	83
A cell biological perspective on Singapore’s scientific growth	83
Waste management and cell death in T cells	82
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	81
It started with a western	81
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	81
Deep-learning for microscopy	80
Telomeres are a life-extending gift	80
Assessing gene loss after gene editing	80
Fat bolsters tumours against ferroptosis	79
Time for lipid cell biology	79
A model for propagation of RNA structural memory through biomolecular condensates	79
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	78
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	78
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	77
Tissue memory relies on stem cell priming in distal undamaged areas	77
Escape from X inactivation is directly modulated by Xist noncoding RNA	75
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells	74
The role of PINK1–Parkin in mitochondrial quality control	72
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	72
Zippering against the beat	72
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	72