OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
STING and fat crosstalk	635
TRIM8 in Ewing sarcoma	420
Force boosts SARS-CoV-2 invasion	350
Enhancing T cell therapy	325
Pushing chromatin to totipotency	267
Restoring placental methylome	213
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	211
Keeping membraneless organelles apart	181
tRNA flux and consistency in differentiation	171
Immune memory in individuals with COVID-19	164
An inflammatory switch for stem cell plasticity	159
COPIng with senescence	157
The guinea pig serves as an alternative model to study human preimplantation development	153
Finding a chaperone for TDP-43	148
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	136
Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity	133
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	129
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	128
ER-associated RNA silencing promotes ER quality control	125
RIPK1 and RIPK3 form mosaic necrosomes	125
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	123
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	120
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	118
A guideline on the molecular ecosystem regulating ferroptosis	117
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	116

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	113
Telomere dysfunction in ageing and age-related diseases	112
Criteria for the standardization of stem-cell-based embryo models	110
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	109
Implementing sustainable science in the lab	106
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	106
A serendipitous discovery of a family of membrane remodelling proteins	106
Regenerating the academic pipeline	104
How a ribosomal protein avoids mixed signals	101
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	101
Nuclear class 3 PI3K coactivates circadian clock	100
Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elements	98
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	95
Real-time and programmable transcriptome sequencing with PROFIT-seq	95
Publisher Correction: p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth	95
The mechanics of crypt morphogenesis	92
Spermidine is essential for fasting-mediated autophagy and longevity	92
PRC2 shields the potency of human stem cells	91
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	90
HSF1 renders NK cells too stressed to respond	90
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	87
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	87
Membranes regulate biomolecular condensates	87
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	86
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	85
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	84
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	81
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	81
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	81
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	80
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	80
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	78
Xist seeds X inactivation	77
A cell biological perspective on Singapore’s scientific growth	77
Sequential enhancer state remodelling defines human germline competence and specification	77
Time for lipid cell biology	77
Deep-learning for microscopy	77
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	76
Tissue memory relies on stem cell priming in distal undamaged areas	75
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	75
A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling	75
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	73
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells	72
Telomeres are a life-extending gift	71
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	71
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	71
Mapping the foetal striatum	71