Cytotherapy

Papers
(The TQCC of Cytotherapy is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)
ArticleCitations
Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles136
International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations 95
Anti-EGFR chimeric antigen receptor-modified T cells in metastatic pancreatic carcinoma: A phase I clinical trial87
Clinical effects of intrathecal administration of expanded Wharton jelly mesenchymal stromal cells in patients with chronic complete spinal cord injury: a randomized controlled study58
Repeated subarachnoid administrations of allogeneic human umbilical cord mesenchymal stem cells for spinal cord injury: a phase 1/2 pilot study55
Generating natural killer cells for adoptive transfer: expanding horizons46
Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition44
Adipose tissue and the vascularization of biomaterials: Stem cells, microvascular fragments and nanofat—a review37
Comparison of regulatory pathways for the approval of advanced therapies in the European Union and the United States36
Current evidence on mesenchymal stem cell therapy for traumatic spinal cord injury: systematic review and meta-analysis33
What does cell therapy manufacturing cost? A framework and methodology to facilitate academic and other small-scale cell therapy manufacturing costings33
Advances in generation of three-dimensional skin equivalents: pre-clinical studies to clinical therapies33
Inducible secretion of IL-21 augments anti-tumor activity of piggyBac-manufactured chimeric antigen receptor T cells32
The effects of intravenous infusion of autologous mesenchymal stromal cells in patients with subacute middle cerebral artery infarct: a phase 2 randomized controlled trial on safety, tolerability and 32
Early CD4+ T cell reconstitution as predictor of outcomes after allogeneic hematopoietic cell transplantation31
Standardized xeno- and serum-free culture platform enables large-scale expansion of high-quality mesenchymal stem/stromal cells from perinatal and adult tissue sources30
Pre-clinical investigation of mesenchymal stromal cell-derived extracellular vesicles: a systematic review30
Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential29
Long-term follow-up of CD19 chimeric antigen receptor T-cell therapy for relapsed/refractory acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation29
Challenges of manufacturing mesenchymal stromal cell–derived extracellular vesicles in regenerative medicine28
Irradiated chimeric antigen receptor engineered NK-92MI cells show effective cytotoxicity against CD19+ malignancy in a mouse model28
Patient access to and ethical considerations of the application of the European Union hospital exemption rule for advanced therapy medicinal products26
Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-h26
Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes26
Leukapheresis guidance and best practices for optimal chimeric antigen receptor T-cell manufacturing25
Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies25
Indirect co-culture of lung carcinoma cells with hyperthermia-treated mesenchymal stem cells influences tumor spheroid growth in a collagen-based 3-dimensional microfluidic model24
The NK-92 cell line—30 years later: its impact on natural killer cell research and treatment of cancer23
Human mesenchymal stromal cells small extracellular vesicles attenuate sepsis-induced acute lung injury in a mouse model: the role of oxidative stress and the mitogen-activated protein kinase/nuclear 23
Amniotic fluid-derived extracellular vesicles: characterization and therapeutic efficacy in an experimental model of bronchopulmonary dysplasia21
Umbilical cord blood-derived mesenchymal stromal cells promote myeloid-derived suppressor cell proliferation by secreting HLA-G to reduce acute graft-versus-host disease after hematopoietic stem cell 21
Mesenchymal stem cells: a new front emerges in coronavirus disease 2019 treatment21
An assessment of the hospital exemption landscape across European Member States: regulatory frameworks, use and impact20
Comparison between centralized and decentralized supply chains of autologous chimeric antigen receptor T-cell therapies: a UK case study based on discrete event simulation20
Advanced therapy medicinal product manufacturing under the hospital exemption and other exemption pathways in seven European Union countries20
Sirtuin 6 regulates macrophage polarization to alleviate sepsis-induced acute respiratory distress syndrome via dual mechanisms dependent on and independent of autophagy19
Advances in automated cell washing and concentration19
Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia19
Release kinetic of pro- and anti-inflammatory biomolecules from platelet-rich plasma and functional study on osteoarthritis synovial fibroblasts19
Consensus International Council for Commonality in Blood Banking Automation–International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin 19
Adenovirus vector-attributed hepatotoxicity blocks clinical application in gene therapy19
Proteomics profile of mesenchymal stromal cells and extracellular vesicles in normoxic and hypoxic conditions19
Non-invasive monitoring of the kinetic infiltration and therapeutic efficacy of nanoparticle-labeled chimeric antigen receptor T cells in glioblastoma via 7.0-Tesla magnetic resonance imaging18
Safety of autologous bone marrow-derived mesenchymal stem cells in erectile dysfunction: an open-label phase 1 clinical trial18
Human umbilical cord mesenchymal stromal cells as an adjunct therapy with therapeutic hypothermia in a piglet model of perinatal asphyxia18
Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model18
Strategies to enhance immunomodulatory properties and reduce heterogeneity in mesenchymal stromal cells during ex vivo expansion17
Registered clinical trials investigating treatment with cell-derived extracellular vesicles: a scoping review17
Analysis of ex vivo expanded and activated clinical-grade human NK cells after cryopreservation16
Differentiation of natural killer cells from induced pluripotent stem cells under defined, serum- and feeder-free conditions16
Umbilical cord-derived mesenchymal stem cells promote myeloid-derived suppressor cell enrichment by secreting CXCL1 to prevent graft-versus-host disease after hematopoietic stem cell transplantation16
Pluripotent stem cell-derived mesenchymal stromal cells improve cardiac function and vascularity after myocardial infarction16
Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression16
γδ T cells cultured with artificial antigen-presenting cells and IL-2 show long-term proliferation and enhanced effector functions compared with γδ T cells cultured with only IL-2 after stimulation wi16
Comparison of umbilical cord tissue-derived mesenchymal stromal cells isolated from cryopreserved material and extracted by explantation and digestion methods utilizing a split manufacturing model16
Anti-tumor effects of vascular endothelial growth factor/vascular endothelial growth factor receptor binding domain-modified chimeric antigen receptor T cells16
Porcine acellular dermal matrix accelerates wound healing through miR-124-3p.1 and miR-139-5p16
Coronavirus disease 2019 pandemic and allogeneic hematopoietic stem cell transplantation: a single center reappraisal15
Nanofiltration of growth media supplemented with human platelet lysates for pathogen-safe xeno-free expansion of mesenchymal stromal cells15
Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues15
Infrapatellar fat pad-derived mesenchymal stromal cell product for treatment of knee osteoarthritis: a first-in-human study with evaluation of the potency marker15
Mesenchymal stem/stromal cell–based therapies for COVID-19: First iteration of a living systematic review and meta-analysis15
Dental pulp stem cell-derived extracellular matrix: autologous tool boosting bone regeneration14
Secretion of human soluble programmed cell death protein 1 by chimeric antigen receptor-modified T cells enhances anti-tumor efficacy14
Mesenchymal stromal cells in wound healing applications: role of the secretome, targeted delivery and impact on recessive dystrophic epidermolysis bullosa treatment14
Safety of allogeneic umbilical cord blood infusions for the treatment of neurological conditions: a systematic review of clinical studies14
Manufacturing chimeric antigen receptor T cells from cryopreserved peripheral blood cells: time for a collect-and-freeze model?14
Fc-engineered anti-CD33 monoclonal antibody potentiates cytotoxicity of membrane-bound interleukin-21 expanded natural killer cells in acute myeloid leukemia14
Engineered exosome-mediated messenger RNA and single-chain variable fragment delivery for human chimeric antigen receptor T-cell engineering14
Antibodies at work in the time of severe acute respiratory syndrome coronavirus 214
1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications14
Estimation of manufacturing development costs of cell-based therapies: a feasibility study14
Effect of mesenchymal stromal cells encapsulated within polyethylene glycol-collagen hydrogels formed in situ on alkali-burned corneas in an ex vivo organ culture model13
CD73 activity of mesenchymal stromal cell-derived extracellular vesicle preparations is detergent-resistant and does not correlate with immunomodulatory capabilities13
Multisite studies for validation and improvement of a highly efficient culture assay for detection of undifferentiated human pluripotent stem cells intermingled in cell therapy products13
The application of stem cell therapy and brown adipose tissue transplantation in metabolic disorders13
Rheumatoid arthritis: From synovium biology to cell-based therapy13
Prevention of chronic diabetic complications in type 1 diabetes by co-transplantation of umbilical cord mesenchymal stromal cells and autologous bone marrow: a pilot randomized controlled open-label c13
Pseudogene PTENP1 sponges miR-214 to regulate the expression of PTEN to modulate osteoclast differentiation and attenuate osteoporosis13
Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): Study protocol for a phase 1 dose-escalation trial of patients with xerostomia after radiation therapy for12
CD20-specific chimeric antigen receptor-expressing T cells as salvage therapy in rituximab-refractory/relapsed B-cell non-Hodgkin lymphoma12
Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma12
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late?12
Particulate impurities in cell-based medicinal products traced by flow imaging microscopy combined with deep learning for image analysis12
Treatment with outgrowth endothelial cells protects cerebral barrier against ischemic injury12
Conditioned media from mesenchymal stromal cells and periodontal ligament fibroblasts under cyclic stretch stimulation promote bone healing in mouse calvarial defects12
CAR19/22 T cell cocktail therapy for B-ALL relapsed after allogeneic hematopoietic stem cell transplantation12
Imaging flow cytometry challenges the usefulness of classically used extracellular vesicle labeling dyes and qualifies the novel dye Exoria for the labeling of mesenchymal stromal cell–extracellular v12
Use of human induced pluripotent stem cells for cartilage regeneration in vitro and within chondral defect models of knee joint cartilage in vivo: a Preferred Reporting Items for Systematic Reviews an12
Glucuronoxylomannan in the Cryptococcus species capsule as a target for Chimeric Antigen Receptor T-cell therapy12
CAR T targets and microenvironmental barriers of osteosarcoma12
Blockade of transforming growth factor β2 by anti-sense oligonucleotide improves immunotherapeutic potential of IL-2 against melanoma in a humanized mouse model11
Identification of protective T-cell antigens for smallpox vaccines11
The safety and efficacy of mesenchymal stem cell therapy in diabetic lower extremity vascular disease: a meta-analysis and systematic review11
A novel non-viral delivery method that enables efficient engineering of primary human T cells for ex vivo cell therapy applications11
Natural killer cells have a synergistic anti-tumor effect in combination with chemoradiotherapy against head and neck cancer11
Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids11
CCR7 expression in CD19 chimeric antigen receptor-engineered natural killer cells improves migration toward CCL19-expressing lymphoma cells and increases tumor control in mice with human lymphoma11
Mesenchymal stem cell secretome protects against alpha-synuclein-induced neurodegeneration in a Caenorhabditis elegans model of Parkinson's disease11
Small extracellular vesicles from mesenchymal stromal cells: the next therapeutic paradigm for musculoskeletal disorders11
Options for imaging cellular therapeutics in vivo: a multi-stakeholder perspective11
Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease11
Macrophage bioassay standardization to assess the anti-inflammatory activity of mesenchymal stromal cell-derived small extracellular vesicles11
Impact of storage conditions and duration on function of native and cargo-loaded mesenchymal stromal cell extracellular vesicles11
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts10
Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay10
Concurrent transposon engineering and CRISPR/Cas9 genome editing of primary CLL-1 chimeric antigen receptor–natural killer cells10
Combined 4-1BB and ICOS co-stimulation improves anti-tumor efficacy and persistence of dual anti-CD19/CD20 chimeric antigen receptor T cells10
A novel predictive algorithm to personalize autologous T-cell harvest for chimeric antigen receptor T-cell manufacture10
Qualification of a multidonor mixed lymphocyte reaction assay for the functional characterization of immunomodulatory extracellular vesicles10
Curative therapy for hemoglobinopathies: an International Society for Cell & Gene Therapy Stem Cell Engineering Committee review comparing outcomes, accessibility and cost of ex vivo stem cell gen10
Presence of innate lymphoid cells in allogeneic hematopoietic grafts correlates with reduced graft-versus-host disease10
CAR-T cell therapy in India requires a paradigm shift in training, education and health care processes10
Progress in the use of mesenchymal stromal cells for osteoarthritis treatment10
Regulatory-compliant conditions during cell product manufacturing enhance in vitro immunomodulatory properties of infrapatellar fat pad-derived mesenchymal stem/stromal cells10
IL-37 overexpression enhances the therapeutic effect of endometrial regenerative cells in concanavalin A-induced hepatitis10
Bispecific targeting of CD20 and CD19 increases polyfunctionality of chimeric antigen receptor T-cell products in B-cell malignancies10
Human umbilical cord tissue-derived mesenchymal stromal cells as adjuvant therapy for myocardial infarction: a review of current evidence focusing on pre-clinical large animal models and early human t10
Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment10
Towards sustainability and affordability of expensive cell and gene therapies? Applying a cost-based pricing model to estimate prices for Libmeldy and Zolgensma10
HLA-A*02:01-directed chimeric antigen receptor/forkhead box P3-engineered CD4+ T cells adopt a regulatory phenotype and suppress established graft-versus-host disease9
Local administration of allogeneic or autologous bone marrow-derived mesenchymal stromal cells enhances bone formation similarly in distraction osteogenesis9
Stem cell-derived exosomes in bone healing: focusing on their role in angiogenesis9
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies9
miR-21-5p in extracellular vesicles obtained from adipose tissue-derived stromal cells facilitates tubular epithelial cell repair in acute kidney injury9
A PHASE I CLINICAL TRIAL ON INTRAVENOUS ADMINISTRATION OF IMMATURE HUMAN DENTAL PULP STEM CELLS (NESTACELL HDTM) TO HUNTINGTON'S DISEASE PATIENTS9
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials9
Targeting of low ALK antigen density neuroblastoma using AND logic-gate engineered CAR-T cells9
Stem cell therapy in coronavirus disease 2019: current evidence and future potential9
Derivation of clinical-grade mesenchymal stromal cells from umbilical cord under chemically defined culture condition – platform for future clinical application9
Identification and characterization of a large source of primary mesenchymal stem cells tightly adhered to bone surfaces of human vertebral body marrow cavities9
Adipose-derived stem cells applied in skin diseases, wound healing and skin defects: a review9
Academic physician specialists’ views toward the unproven stem cell intervention industry: areas of common ground and divergence9
Identification of marker genes to monitor residual iPSCs in iPSC-derived products9
Validation of a flow cytometry-based method to quantify viable lymphocyte subtypes in fresh and cryopreserved hematopoietic cellular products8
The capacity of CD4+ Vγ9Vδ2 T cells to kill cancer cells correlates with co-expression of CD568
Metformin pre-treatment of stem cells from human exfoliated deciduous teeth promotes migration and angiogenesis of human umbilical vein endothelial cells for tissue engineering8
Identification of novel HLA-restricted preferentially expressed antigen in melanoma peptides to facilitate off-the-shelf tumor-associated antigen-specific T-cell therapies8
Transient blockade of TBK1/IKKε allows efficient transduction of primary human natural killer cells with vesicular stomatitis virus G-pseudotyped lentiviral vectors8
Artificial feeder cells expressing ligands for killer cell immunoglobulin-like receptors and CD94/NKG2A for expansion of functional primary natural killer cells with tolerance to self8
Effect of adoptive T-cell immunotherapy on immunological parameters and prognosis in patients with advanced pancreatic cancer8
Mapping human serum–induced gene networks as a basis for the creation of biomimetic periosteum for bone repair8
Extracorporeal photopheresis as first-line strategy in the treatment of acute graft-versus-host disease after hematopoietic stem cell transplantation: A single-center experience8
A comprehensive report of long-term stability data for a range ATMPs: A need to develop guidelines for safe and harmonized stability studies8
Transcriptional dynamics of induced pluripotent stem cell differentiation into β cells reveals full endodermal commitment and homology with human islets8
Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion8
MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease8
Development of an induced pluripotent stem cell–specific microRNA assay for detection of residual undifferentiated cells in natural killer cell therapy products7
A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, “Therapeutic advances with native and engineered human extracellular vesicles”7
Cryopreserved bone marrow aspirate concentrate as a cell source for the colony-forming unit fibroblast assay7
Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use7
Effect of intramuscular baculovirus encoding mutant hypoxia-inducible factor 1-alpha on neovasculogenesis and ischemic muscle protection in rabbits with peripheral arterial disease7
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells Committee editorial on overcoming limitations in clinical trials of mesenchymal stromal cell therapy for coronavirus diseas7
Developing lisocabtagene maraleucel chimeric antigen receptor T-cell manufacturing for improved process, product quality and consistency across CD19+ hematologic indications7
Editing human hematopoietic stem cells: advances and challenges7
Role of mesenchymal stromal cells derivatives in diabetic foot ulcers: a controlled randomized phase 1/2 clinical trial7
Spike-directed vaccination elicits robust spike-specific T-cell response, including to mutant strains7
Evaluation of a clinical-grade, cryopreserved, ex vivo-expanded stem cell product from cryopreserved primary umbilical cord blood demonstrates multilineage hematopoietic engraftment in mouse xenograft7
Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufac7
In vitro induction of neoantigen-specific T cells in myelodysplastic syndrome, a disease with low mutational burden7
A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis7
Response to extracorporeal photopheresis therapy of patients with steroid-refractory/-resistant GvHD is associated with up-regulation of Th22 cells and Tfh cells7
Non-cryopreserved hematopoietic stem cells in autograft patients with lymphoma: a matched-pair analysis comparing a single center experience with the use of cryopreserved stem cells reported to the Eu7
Infusion reactions in natural killer cell immunotherapy: a retrospective review7
Mesenchymal stromal cell therapy for coronavirus disease 2019: which? when? and how much?7
γc cytokine-aided crosstalk between dendritic cells and natural killer cells together with doxorubicin induces a healer response in experimental lymphoma by downregulating FOXP3 and programmed cell de7
Emerging frontiers in immuno- and gene therapy for cancer7
Development of a quantitative prediction model for peripheral blood stem cell collection yield in the plerixafor era7
Stem cells from human exfoliated deciduous teeth affect mitochondria and reverse cognitive decline in a senescence-accelerated mouse prone 8 model7
Pre-clinical development and molecular characterization of an engineered type 1 regulatory T-cell product suitable for immunotherapy7
CD40L-expressing CD4+ T cells prime adipose-derived stromal cells to produce inflammatory chemokines7
Allogeneic cord blood regulatory T cells can resolve lung inflammation6
International Society for Cell & Gene Therapy Position Paper: Key considerations to support evidence-based cell and gene therapies and oppose marketing of unproven products6
A serum-free protocol for the ex vivo expansion of Cytokine-Induced Killer cells using gas-permeable static culture flasks6
Adverse effect of donor-specific anti-human leukocyte antigen (HLA) antibodies directed at HLA-DP/-DQ on engraftment in cord blood transplantation6
Pancreatic cancer growth promoted by bone marrow mesenchymal stromal cell–derived IL-6 is reversed predominantly by IL-6 blockade6
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PIK3R2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells6
Transient warming affects potency of cryopreserved cord blood units6
Reversion of early- and late-stage β-cell dedifferentiation by human umbilical cord-derived mesenchymal stem cells in type 2 diabetic mice6
Live cell imaging of highly activated natural killer cells against human hepatocellular carcinoma in vivo6
Minor salivary gland mesenchymal stromal cells derived from patients with Sjӧgren's syndrome deploy intact immune plasticity6
Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness6
Evaluation of human adipose-derived mesenchymal stromal cell Toll-like receptor priming and effects on interaction with prostate cancer cells6
High-throughput assessment of mutations generated by genome editing in induced pluripotent stem cells by high-resolution melting analysis6
Bone marrow toxicity and immune reconstitution in melanoma and non-melanoma solid cancer patients after non-myeloablative conditioning with chemotherapy and checkpoint inhibition6
Characterization and response to inflammatory stimulation of human endometrial-derived mesenchymal stem/stromal cells6
Recent advances in cellular therapy for malignant lymphoma6
Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory multiple myeloma6
Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy6
Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform6
Rapid single-cell identification of Epstein–Barr virus-specific T-cell receptors for cellular therapy6
Adoptive transfer of neoantigen-specific T-cell therapy is feasible in older patients with higher-risk myelodysplastic syndrome6
Effect of alemtuzumab-based T-cell depletion on graft compositional change in vitro and immune reconstitution early after allogeneic stem cell transplantation5
CRISPR-Cas9 base editors and their current role in human therapeutics5
Effect of mesenchymal stromal cell transplantation on long-term survival in amyotrophic lateral sclerosis5
Perspectives on establishing a public cord blood inventory in South Africa5
Application of decellularized human reticular allograft dermal matrix promotes rapid re-epithelialization in a diabetic murine excisional wound model5
Endoscopic atomization of mesenchymal stromal cells: in vitro study for local cell therapy of the lungs5
Effects of stem cells on non-ischemic cardiomyopathy: a systematic review and meta-analysis of randomized controlled trials5
The new legal framework for minimally manipulated cells expands the possibilities for cell therapy in Russia5
Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 20195
Cytotoxic activity of anti-mucin 1 chimeric antigen receptor T cells expressing PD-1-CD28 switch receptor against cholangiocarcinoma cells5
Mitochondrial DNA from osteoarthritic patients drives functional impairment of mitochondrial activity: a study on transmitochondrial cybrids5
Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): A pilot, first-in-human study of interferon gamma–stimulated marrow mesenchymal stromal cells for treatmen5
Cell and gene therapy: a snapshot of investor perspectives5
Mesenchymal stromal cell therapy for acute respiratory distress syndrome due to coronavirus disease 20195
A biomarker-guided, prospective, phase 2 trial of pre-emptive graft-versus-host disease therapy using anti-thymocyte globulin5
Comparative analysis of cell therapy infusion workflows at clinical sites5
Engineering of regulatory T cells by means of mRNA electroporation in a GMP-compliant manner5
ISCT survey on hospital practices to support externally manufactured investigational cell-gene therapy products5
Technological advances in study of lung regenerative medicine:perspective from the 2019 Vermont lung stem cell conference5
A risk-based approach for cell line development, manufacturing and characterization of genetically engineered, induced pluripotent stem cell–derived allogeneic cell therapies5
Improving cell viability using counterflow centrifugal elutriation5
Soluble factors differ in platelets derived from separate niches: a pilot study comparing the secretome of peripheral blood and bone marrow platelets5
Efficacy of mesenchymal stromal cells intraspinal transplantation for patients with different degrees of spinal cord injury: A systematic review and meta-analysis5
Characterization of heterogeneous primary human cartilage-derived cell population using non-invasive live-cell phase-contrast time-lapse imaging5
Consequences of adjusting cell density and feed frequency on serum-free expansion of thymic regulatory T cells5
An industry survey of implementation strategies for clinical supply chain management of cell and gene therapies5
Crosstalk of renal cell carcinoma cells and tumor-associated macrophages aggravates tumor progression by modulating muscleblind-like protein 2/B-cell lymphoma 2/beclin 1-mediated autophagy5
Phospholipids in small extracellular vesicles: emerging regulators of neurodegenerative diseases and cancer5
Systematic review and meta-analysis of the association between bridging therapy and outcomes of chimeric antigen receptor T cell therapy in patients with large B cell lymphoma5
Cell and gene therapy products in Malaysia: a snapshot of the industry's current regulation preparedness5
Advantages of peripheral blood stem cells from unrelated donors versus bone marrow transplants in outcomes of adult acute myeloid leukemia patients5
Hematopoietic stem cell transplantation for uncommon immune-mediated neurological disorders: A literature review5
Development of a B-cell maturation antigen-specific T-cell antigen coupler receptor for multiple myeloma5
Combinatorial antigen targeting strategies for acute leukemia: application in myeloid malignancy4
Impact of contracted manufacturing organization protocols on operations in an aca demically based Current Good Manufacturing Practice facility4
Scientific venturing for early-stage professionals (ESPs), a key concept in the innovation ecosystem4
Removal of minute virus of mice-mock virus particles by nanofiltration of culture growth medium supplemented with 10% human platelet lysate4
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone 4
Longitudinal two-dimensional gas chromatography mass spectrometry as a non-destructive at-line monitoring tool during cell manufacturing identifies volatile features correlative to cell product qualit4
CRISPR/Cas9-mediated gene editing. A promising strategy in hematological disorders4
Cell and gene therapy workforce development: the role of the International Society for Cell & Gene Therapy (ISCT) in the creation of a sustainable and skilled workforce in Europe4
Reference gene selection for clinical chimeric antigen receptor T-cell product vector copy number assays4
Bone marrow-derived inducible microglia-like cells ameliorate motor function and survival in a mouse model of amyotrophic lateral sclerosis4
Accommodating clinical trials and other externally manufactured cellular therapy products: challenges, lessons learned and creative solutions4
A comprehensive review of quantum bioreactor cell manufacture: Research and clinical applications4
Crowdfunding, stem cell interventions and autism spectrum disorder: comparing campaigns related to an international “stem cell clinic” and US academic medical center4
Manufacturing and validation of Good Manufacturing Practice–compliant regulatory dendritic cells for infusion into organ transplant recipients4
A hub-and-spoke model to deliver effective access to chimeric antigen receptor T-cell therapy in a public health network: the Catalan Blood and Tissue Bank experience4
Long-term outcomes of relmacabtagene autoleucel in Chinese patients with relapsed/refractory large B-cell lymphoma: Updated results of the RELIANCE study4
Validation plan of bone marrow collection, processing and distribution using the failure mode and effect analysis methodology: a technical report4
Early immune reconstitution as predictor for outcomes after allogeneic hematopoietic cell transplant; a tri-institutional analysis4
Reduced dimethyl sulfoxide concentrations successfully cryopreserve human hematopoietic stem cells with multi-lineage long-term engraftment ability in mice4
Predictive analytics and cord blood banking: toward utilization-based unit selection4
The systemic administration of neural stem cells expressing an inducible and soluble form of growth arrest specific 1 inhibits mammary gland tumor growth and the formation of metastases4
Assessment of anti-inflammatory bioactivity of extracellular vesicles is susceptible to error via media component contamination4
Non-clinical assessment of cell therapy products: the perspective from five Asian countries/regions based on regulatory guidelines and the underpinning rationales4
Promoting the ethical use of safe and effective cell-based products: the Andalusian plan on regenerative medicine4
ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa4
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