Cytotherapy

Papers
(The TQCC of Cytotherapy is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-06-01 to 2023-06-01.)
ArticleCitations
Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Th1290
Yield of human adipose-derived adult stem cells from liposuction aspirates537
Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature370
Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: produc216
Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture211
Isolation and characterization of mesenchymal progenitor cells from chorionic villi of human placenta211
Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy210
Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM199
Mesenchymal stem/progenitor cells developed in cultures from UC blood181
Exosomes from dental pulp stem cells rescue human dopaminergic neurons from 6-hydroxy-dopamine–induced apoptosis158
Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells151
Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6140
A 37-year-old spinal cord-injured female patient, transplanted of multipotent stem cells from human UC blood, with improved sensory perception and mobility, both functionally and morphologically: a ca122
Zoledronate facilitates large-scale ex vivo expansion of functional γδ T cells from cancer patients for use in adoptive immunotherapy*114
Human adipose-derived stem cells isolated from young and elderly women: their differentiation potential and scaffold interaction during in vitro osteoblastic differentiation110
Manufacturing and characterization of extracellular vesicles from umbilical cord–derived mesenchymal stromal cells for clinical testing110
Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device109
Exosomes derived from endothelial progenitor cells attenuate vascular repair and accelerate reendothelialization by enhancing endothelial function108
Hepatoprotective effect of exosomes from human-induced pluripotent stem cell–derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats102
Safety evaluation of exosomes derived from human umbilical cord mesenchymal stromal cell98
Comparison of mesenchymal stromal cells from human bone marrow and adipose tissue for the treatment of spinal cord injury97
Secretomes from bone marrow–derived mesenchymal stromal cells enhance periodontal tissue regeneration95
Anterior cruciate ligament constructs fabricated from human mesenchymal stem cells in a collagen type I hydrogel94
Enhancement of wound healing by secretory factors of endothelial precursor cells derived from human embryonic stem cells89
Highly enriched cardiomyocytes from human embryonic stem cells89
Implantation of BM mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys88
Comparison of human mesenchymal stem cells derived from adipose and cord tissue88
Mesenchymal stromal cell therapy: progress in manufacturing and assessments of potency88
Insulin-secreting adipose-derived mesenchymal stromal cells with bone marrow–derived hematopoietic stem cells from autologous and allogenic sources for type 1 diabetes mellitus84
A large-scale method for the selective depletion of αβ T lymphocytes from PBSC for allogeneic transplantation82
Human mesenchymal stromal cells from adult and neonatal sources: comparative analysis of their morphology, immunophenotype, differentiation patterns and neural protein expression80
International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations 78
Conditioned medium from amniotic mesenchymal tissue cells reduces progression of bleomycin-induced lung fibrosis78
An alternative method for the isolation of mesenchymal stromal cells derived from lipoaspirate samples77
Cell sheet technology: a promising strategy in regenerative medicine77
Manufacturing chimeric antigen receptor T cells: issues and challenges76
Characterization and expansion of mesenchymal progenitor cells from first-trimester chorionic villi of human placenta74
Differentiation of mesenchymal stromal cells derived from umbilical cord Wharton's jelly into hepatocyte-like cells72
Safety and efficacy of allogenic placental mesenchymal stem cells for treating knee osteoarthritis: a pilot study72
Freshly isolated stromal cells from the infrapatellar fat pad are suitable for a one-step surgical procedure to regenerate cartilage tissue72
Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells70
Tumorigenicity assessment of cell therapy products: The need for global consensus and points to consider70
Factors secreted from dental pulp stem cells show multifaceted benefits for treating acute lung injury in mice69
Survival of human mesenchymal stromal cells from bone marrow and adipose tissue after xenogenic transplantation in immunocompetent mice64
Generation of confluent cardiomyocyte monolayers derived from embryonic stem cells in suspension: a cell source for new therapies and screening strategies64
Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial63
Transplantation of islet-like cell clusters derived from human dental pulp stem cells restores normoglycemia in diabetic mice63
Comparative study of stemness characteristics of mesenchymal cells from bone marrow of children and adults63
Age influence on stromal vascular fraction cell yield obtained from human lipoaspirates61
Low oxygen atmosphere facilitates proliferation and maintains undifferentiated state of umbilical cord mesenchymal stem cells in an hypoxia inducible factor-dependent manner60
Exosome-transmitted LINC00461 promotes multiple myeloma cell proliferation and suppresses apoptosis by modulating microRNA/BCL-2 expression60
Comparative analysis of the immunomodulatory capacities of human bone marrow– and adipose tissue–derived mesenchymal stromal cells from the same donor58
Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro58
Qualitative and quantitative differences of adipose-derived stromal cells from superficial and deep subcutaneous lipoaspirates: a matter of fat57
Comparison of human mesenchymal stromal cells from four neonatal tissues: Amniotic membrane, chorionic membrane, placental decidua and umbilical cord55
Conditioned medium from amniotic membrane-derived cells prevents lung fibrosis and preserves blood gas exchanges in bleomycin-injured mice—specificity of the effects and insights into possible mechani54
Neural differentiation ability of mesenchymal stromal cells from bone marrow and adipose tissue: a comparative study54
Epidermal growth factor, basic fibroblast growth factor and platelet-derived growth factor-bb can substitute for fetal bovine serum and compete with human platelet-rich plasma in the ex vivo expansion54
Preservation of cell-based immunotherapies for clinical trials54
Selection of CD271+ cells and human AB serum allows a Large expansion of mesenchymal stromal cells from human bone marrow54
Proliferation, differentiation and characterization of osteoblasts from human BM mesenchymal cells53
Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease52
Characterization of mesenchymal stromal cells derived from full-term umbilical cord blood51
Stem cells from human exfoliated deciduous teeth (SHED) enhance wound healing and the possibility of novel cell therapy51
Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q50
Expansion of HPCs from cord blood in a novel 3D matrix49
Extracellular vesicles released from mesenchymal stromal cells stimulate bone growth in osteogenesis imperfecta49
Chimeric antigen receptor–T cell therapy manufacturing: modelling the effect of offshore production on aggregate cost of goods49
Impaired differentiation potential of human trabecular bone mesenchymal stromal cells from elderly patients49
Manufacturing mesenchymal stromal cells for clinical applications: A survey of Good Manufacturing Practices at U.S. academic centers49
Endothelial progenitor cell therapy for chronic wound tissue regeneration48
Surface characterization and chondrogenic differentiation of mesenchymal stromal cells derived from synovium48
A simple and efficient method for generating Nurr1-positive neuronal stem cells from human wisdom teeth (tNSC) and the potential of tNSC for stroke therapy47
Morphological profiling using machine learning reveals emergent subpopulations of interferon-γ–stimulated mesenchymal stromal cells that predict immunosuppression46
Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells45
Treatment of human cells derived from MERRF syndrome by peptide-mediated mitochondrial delivery45
Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure44
Monocyte enrichment from leukapharesis products for the generation of DCs by plastic adherence, or by positive or negative selection44
Mesenchymal stem cells in the treatment of articular cartilage degeneration: New biological insights for an old-timer cell44
Multipotent mesenchymal stem cells from amniotic fluid originate neural precursors with functional voltage-gated sodium channels43
Comparative analysis of mesenchymal stromal cells from murine bone marrow and amniotic fluid42
Immunosuppressive properties of mesenchymal stromal cell cultures derived from the limbus of human and rabbit corneas41
Reversal of experimental diabetes in mice by transplantation of neo-islets generated from human amnion-derived mesenchymal stromal cells using immuno-isolatory macrocapsules40
Bone marrow-derived mesenchymal stromal cells from patients with end-stage renal disease are suitable for autologous therapy40
Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab38
In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells37
The adipose tissue–derived stromal vascular fraction cells from lipedema patients: Are they different?37
Efficient expansion of mesenchymal stromal cells from umbilical cord under low serum conditions37
Cryopreservation has no effect on function of natural killer cells differentiated in vitro from umbilical cord blood CD34 + cells36
Bilateral administration of autologous CD133+ cells in ambulatory patients with refractory critical limb ischemia: lessons learned from a pilot randomized, double-blind, placebo-controlled trial36
Evaluation of a cell-banking strategy for the production of clinical grade mesenchymal stromal cells from Wharton's jelly36
Efficacy and safety of mesenchymal stromal cell treatment from related donors for patients with refractory aplastic anemia35
A robust, good manufacturing practice–compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy35
Exosomes from mesenchymal stromal cells enhance imatinib-induced apoptosis in human leukemia cells via activation of caspase signaling pathway35
Mesenchymal stromal cells from dermal and adipose tissues induce macrophage polarization to a pro-repair phenotype and improve skin wound healing34
Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: a joint publication from the AABB and the International Society for Cell & Gene Therapy34
Isolation and characterization of mesenchymal stromal cells from human anterior cruciate ligament34
Development of a clinical-scale method for generation of dendritic cells from PBMC for use in cancer immunotherapy34
Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study33
Analysis and cryopreservation of hematopoietic stem and progenitor cells from umbilical cord blood33
Fetal mesenchymal stromal cells from cryopreserved human chorionic villi: cytogenetic and molecular analysis of genome stability in long-term cultures33
Novel cryoprotectant significantly improves the post-thaw recovery and quality of HSC from CB33
Isolation of stem cell populations with trophic and immunoregulatory functions from human intestinal tissues: potential for cell therapy in inflammatory bowel disease33
Transfer of PR1-specific T-cell clones from donor to recipient by stem cell transplantation and association with GvL activity33
Comparative analysis of multilineage properties of mesenchymal stromal cells derived from fetal sources shows an advantage of mesenchymal stromal cells isolated from cord blood in chondrogenic differe33
Loss of Thy-1 (CD90) antigen expression on mesenchymal stromal cells from hematologic malignancies is induced by in vitro angiogenic stimuli and is associated with peculiar functional and phenotypic c32
In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials32
Good manufacturing practice-grade production of unrestricted somatic stem cell from fresh cord blood32
Current state of U.S. Food and Drug Administration regulation for cellular and gene therapy products: potential cures on the horizon32
Quality compliance in the shift from cell transplantation to cell therapy in non-pharma environments32
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer31
Consistent bone marrow-derived cell mobilization following repeated short courses of granulocyte–colony-stimulating factor in patients with amyotrophic lateral sclerosis: results from a multicenter pr31
Direct transplantation of native pericytes from adipose tissue: A new perspective to stimulate healing in critical size bone defects31
A comparative analysis of the adipogenic potential in human mesenchymal stromal cells from cord blood and other sources31
Rapamycin enriches for CD4+ CD25+ CD27+ Foxp3+ regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis31
Gamma delta T cells from HIV+ donors can be expanded in vitro by zoledronate/interleukin-2 to become cytotoxic effectors for antibody-dependent cellular cytotoxicity30
Small extracellular vesicle loading systems in cancer therapy: Current status and the way forward30
Mesenchymal stem cell–derived extracellular vesicles: a new impetus of promoting angiogenesis in tissue regeneration30
Enhanced neuro-therapeutic potential of Wharton's Jelly–derived mesenchymal stem cells in comparison with bone marrow mesenchymal stem cells culture30
Individual and combined effects of mesenchymal stromal cells and recombinant stimulatory cytokines on the in vitro growth of primitive hematopoietic cells from human umbilical cord blood29
Characterization of hematopoietic stem cell subsets from patients with multiple myeloma after mobilization with plerixafor28
Translation of a standardized manufacturing protocol for mesenchymal stromal cells: A systematic comparison of validation and manufacturing data28
Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate28
Isolation of oligodendrocyte-like cells from human umbilical cord blood28
Robust polyfunctional T-helper 1 responses to multiple fungal antigens from a cell population generated using an environmental strain of Aspergillus fumigatus28
Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Aβ1-40-injected mouse model of Alzheimer's disease28
Intrastriatal transplantation of stem cells from human exfoliated deciduous teeth reduces motor defects in Parkinsonian rats27
Efficient isolation and enrichment of mesenchymal stem cells from bone marrow26
Stem cell–based biological pacemakers from proof of principle to therapy: a review26
Human parainfluenza virus-3 can be targeted by rapidly ex vivo expanded T lymphocytes26
T-lymphocyte function from peripheral blood stem-cell donors is inhibited by activated granulocytes26
Comparative characterization of bone marrow-derived mesenchymal stromal cells from four different rat strains26
Isolation and characterization of stem cells from pancreatic islet: pluripotency, differentiation potential and ultrastructural characteristics26
Isolation and expansion of oligodendrocyte progenitor cells from cryopreserved human umbilical cord blood26
Umbilical cord tissue–derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing26
Tumor-infiltrating lymphocytes: Streamlining a complex manufacturing process25
Overcoming the bottleneck of platelet lysate supply in large-scale clinical expansion of adipose-derived stem cells: A comparison of fresh versus three types of platelet lysates from outdated buffy co25
Immunosuppressive capabilities of mesenchymal stromal cells are maintained under hypoxic growth conditions and after gamma irradiation25
Biologic and immunomodulatory properties of mesenchymal stromal cells derived from human pancreatic islets24
Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential24
Ex vivo activation and expansion of natural killer cells from patients with advanced cancer with feeder cells from healthy volunteers24
Development and validation of a procedure to isolate viable bone marrow cells from the vertebrae of cadaveric organ donors for composite organ grafting24
Adipose-derived mesenchymal stromal cells from genetically modified pigs: immunogenicity and immune modulatory properties24
Ex vivo expansion of natural killer cells from human peripheral blood mononuclear cells co-stimulated with anti-CD3 and anti-CD52 monoclonal antibodies24
Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies24
Improving clinical outcomes using adoptively transferred immune cells from umbilical cord blood24
Cellular magnetic resonance imaging of monocyte-derived dendritic cell migration from healthy donors and cancer patients as assessed in a scid mouse model23
A novel method to expand large numbers of CD56+ natural killer cells from a minute fraction of selectively accessed cryopreserved cord blood for immunotherapy after transplantation23
MSCs can be differentially isolated from maternal, middle and fetal segments of the human umbilical cord22
Sildenafil improves long-term effect of endothelial progenitor cell-based treatment for monocrotaline-induced rat pulmonary arterial hypertension22
Transplantation of porcine embryonic stem cells and their derived neuronal progenitors in a spinal cord injury rat model22
Variation in primary and culture-expanded cells derived from connective tissue progenitors in human bone marrow space, bone trabecular surface and adipose tissue22
Aggregation of human mesenchymal stem cells enhances survival and efficacy in stroke treatment22
Mesenchymal stromal cells from the foreskin: Tissue isolation, cell characterization and immunobiological properties21
Optimization of manufacturing conditions for chimeric antigen receptor T cells to favor cells with a central memory phenotype21
Type I IFN-mediated enhancement of anti-leukemic cytotoxicity of γδ T cells expanded from peripheral blood cells by stimulation with zoledronate20
Determination of residual T- and B-cell content after immunomagnetic depletion: proposal for flow cytometric analysis and results from 103 separations20
Autologous cryopreserved leukapheresis cellular material for chimeric antigen receptor–T cell manufacture20
PARKIN overexpression in human mesenchymal stromal cells from Wharton's jelly suppresses 6-hydroxydopamine–induced apoptosis: Potential therapeutic strategy in Parkinson's disease20
Mesenchymal stromal cells derived from CD271+ bone marrow mononuclear cells exert potent allosuppressive properties20
Comparative characterization of mesenchymal stromal cells from multiple abdominal adipose tissues and enrichment of angiogenic ability via CD146 molecule20
Placental mesenchymal stromal cells induced into neurotrophic factor-producing cells protect neuronal cells from hypoxia and oxidative stress20
Bone marrow–derived mesenchymal stromal cells ameliorate severe acute pancreatitis in rats via hemeoxygenase-1–mediated anti-oxidant and anti-inflammatory effects20
Mesenchymal stromal cells isolated from children with systemic juvenile idiopathic arthritis suppress innate and adaptive immune responses19
Mesenchymal stem cells: a new front emerges in coronavirus disease 2019 treatment19
A highly standardized and characterized human platelet lysate for efficient and reproducible expansion of human bone marrow mesenchymal stromal cells19
Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture19
Fetal liver-conditioned medium induces hepatic specification from mouse bone marrow mesenchymal stromal cells: a novel strategy for hepatic transdifferentiation19
Prospective isolation of stromal progenitor cells from mouse BM19
Identification of senescent cells in multipotent mesenchymal stromal cell cultures: Current methods and future directions19
Preclinical characterization of DUOC-01, a cell therapy product derived from banked umbilical cord blood for use as an adjuvant to umbilical cord blood transplantation for treatment of inherited metab19
Standardized xeno- and serum-free culture platform enables large-scale expansion of high-quality mesenchymal stem/stromal cells from perinatal and adult tissue sources19
Uptake of antigens from modified vaccinia Ankara virus-infected leukocytes enhances the immunostimulatory capacity of dendritic cells19
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy19
Mesenchymal stem cells preconditioned by staphylococcal enterotoxin B enhance survival and bacterial clearance in murine sepsis model19
Levels of IL-17F and IL-33 correlate with HLA-DR activation in clinical-grade human bone marrow–derived multipotent mesenchymal stromal cell expansion cultures18
Transplantation of mesenchymal stromal cells on mineralized collagen leads to ectopic matrix synthesis in vivo independently from prior in vitro differentiation18
Proteomic analysis of human mesenchymal stromal cells derived from adipose tissue undergoing osteoblast differentiation18
Derivation of lung epithelium from bone marrow cells18
Functional and immunophenotypic characteristics of isolated CD105+ and fibroblast+ stromal cells from AML: implications for their plasticity along endothelial lineage18
HLA tetramers and anti-CMV immune responses: from epitope to immunotherapy18
Enhanced generation of megakaryocytes from umbilical cord blood-derived CD34+ cells expanded in the presence of two nutraceuticals, docosahexanoic acid and arachidonic acid, as supplements to the cyto18
Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies18
Enrichment isolation of adipose-derived stem/stromal cells from the liquid portion of liposuction aspirates with the use of an adherent column17
Insulin-like growth factor 2 regulates the proliferation and differentiation of rat adipose-derived stromal cells via IGF-1R and IR17
Detection of isolated tumor cells in BM from breast-cancer patients: significance of anterior and posterior iliac crest aspirations and the number of mononuclear cells analyzed17
Mesenchymal-like progenitors derived from human embryonic stem cells promote recovery from acute kidney injury via paracrine actions17
DSP30 enhances the immunosuppressive properties of mesenchymal stromal cells and protects their suppressive potential from lipopolysaccharide effects: A potential role of adenosine17
Development and operation of a quality assurance system for deviations from standard operating procedures in a clinical cell therapy laboratory17
Impact of chronicity of injury on the proportion of mesenchymal stromal cells derived from anterior cruciate ligaments16
Properties and potential of bone marrow mesenchymal stromal cells from children with hematologic diseases16
Hematopoietic recovery of acute radiation syndrome by human superoxide dismutase–expressing umbilical cord mesenchymal stromal cells16
A multiscale simulation framework for the manufacturing facility and supply chain of autologous cell therapies16
Evaluation of mobilized peripheral blood CD34+ cells from patients with severe coronary artery disease as a source of endothelial progenitor cells16
Mesenchymal stromal cells from donors varying widely in age are of equal cellular fitness after in vitro expansion under hypoxic conditions16
Three specific antigens to isolate endothelial progenitor cells from human liposuction material16
Impaired circulating myeloid DCs from myeloma patients16
Recent progress on developing exogenous monocyte/macrophage-based therapies for inflammatory and degenerative diseases16
Adoptive immunotherapy with the use of regulatory T cells and virus-specific T cells derived from cord blood16
In vitro characterization of two lineage-negative CD34+ cell-enriched hematopoietic cell populations from human UC blood16
Mesenchymal stromal cells from unconventional model organisms16
Progress in the application of exosomes as therapeutic vectors in tumor-targeted therapy16
Phenotypic characterization and anti-tumor effects of cytokine-induced killer cells derived from cord blood15
Sub-confluent culture of human mesenchymal stromal cells on biodegradable polycaprolactone microcarriers enhances bone healing of rat calvarial defect15
Clinical-grade manufacturing of DC from CD14+ precursors: experience from phase I clinical trials in CML and malignant melanoma15
Immunotherapy in atypical teratoid-rhabdoid tumors: Data from a survey of the HGG-Immuno Group15
Selective elimination of alloreactivity from immunotherapeutic T cells by photodynamic cell purging and memory T-cell sorting15
Epstein-Barr Virus (EBV)-derived BARF1 encodes CD4- and CD8-restricted epitopes as targets for T-cell immunotherapy15
A comparison of ex vivo expanded DCs derived from cord blood and mobilized adult peripheral blood plastic-adherent mononuclear cells: decreased alloreactivity of cord blood DCs15
Isolation and trans-differentiation of mesenchymal stromal cells into smooth muscle cells: Utility and applicability for cell-sheet engineering15
A phase II randomized clinical trial for the treatment of recalcitrant chronic leg ulcers using centrifuged adipose tissue containing progenitor cells15
Herpes simplex virus type 1 (HSV-1) specific T-cell generation from HLA-A1- and HLA-A2-positive donors for adoptive immunotherapy14
Prediction of CD34 + cell yield in hematopoietic cell products from children by peripheral blood CD34 + cell counts14
CD133 immunomagnetic separation: effectiveness of the method for CD133+ isolation from umbilical cord blood14
CD19 chimeric antigen receptor (CAR) engineered epstein-barr virus (EBV) specific T cells – an off-the-shelf, allogeneic CAR T-cell immunotherapy platform14
Functional and ultrastructural analysis of endothelial-like cells derived from bone marrow stromal cells14
Telomerase activity and expression in adult human mesenchymal stem cells derived from amyotrophic lateral sclerosis individuals14
Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol14
Cycloxygenase-2 inhibition potentiates trans-differentiation of Wharton's jelly–mesenchymal stromal cells into endothelial cells: Transplantation enhances neovascularization-mediated wound repair14
Production of erythrocytes from directly isolated or Delta1 Notch ligand expanded CD34+ hematopoietic progenitor cells: process characterization, monitoring and implications for manufacture14
Combined use of N-acetylcysteine and Liberase improves the viability and metabolic function of human hepatocytes isolated from human liver14
Ex vivo expansion of neutrophil precursor cells from fresh and cryopreserved cord blood cells14
Optimizing the transport and storage conditions of current Good Manufacturing Practice –grade human umbilical cord mesenchymal stromal cells for transplantation (HUC-HEART Trial)14
Expanded umbilical cord blood T cells used as donor lymphocyte infusions after umbilical cord blood transplantation14
Derivation of male germ cells from induced pluripotent stem cells by inducers: A review13
Three-dimensional culture and characterization of mononuclear cells from human bone marrow13
Improvement of in vitro potency assays by a resting step for clinical-grade chimeric antigen receptor engineered T cells13
Current state of Health Canada regulation for cellular and gene therapy products: potential cures on the horizon13
Dendritic cell vaccination in an allogeneic stem cell recipient receiving a transplant from a human cytomegalovirus (HCMV)-seronegative donor: induction of a HCMV-specific Thelper cell response13
Allogeneic chondrogenically differentiated human mesenchymal stromal cells do not induce immunogenic responses from T lymphocytes in vitro13
Differential properties of human stromal cells from bone marrow, adipose, liver and cardiac tissues13
The efficacy of anti-CD19 chimeric antigen receptor T cells for B-cell malignancies13
Response to Nature commentary “Clear up this stem-cell mess”13
Mesenchymal stromal cells from umbilical cord Wharton's jelly trigger oligodendroglial differentiation in neural progenitor cells through cell-to-cell contact13
Release kinetic of pro- and anti-inflammatory biomolecules from platelet-rich plasma and functional study on osteoarthritis synovial fibroblasts13
NK92-CD16 cells are cytotoxic to non-small cell lung cancer cell lines that have acquired resistance to tyrosine kinase inhibitors13
Umbilical cord–derived mesenchymal stromal cells in cardiovascular disease: review of preclinical and clinical data13
Manufacturing of human Wharton's jelly stem cells for clinical use: selection of serum is important12
Preparation of functionally preserved CD4+ CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell transfer therapy12
Coronavirus disease 2019 pandemic and allogeneic hematopoietic stem cell transplantation: a single center reappraisal12
DC-based cancer vaccines: lessons from clinical trials12
Retropatellar fat pad–derived stem cells from older osteoarthritic patients have lesser differentiation capacity and expression of stemness genes12
Differentiated human adipose-derived stromal cells exhibit the phenotypic and functional characteristics of mature Schwann cells through a modified approach12
Insights into animal models for cell-based therapies in translational studies of lung diseases: Is the horse with naturally occurring asthma the right choice?12
CFU-megakaryocytic progenitors expanded ex vivo from cord blood maintain their in vitro homing potential and express matrix metalloproteinases12
Comparison of two methodologies for the enrichment of mononuclear cells from thawed cord blood products: The automated Sepax system versus the manual Ficoll method11
Transforming growth factor-β1-overexpressing mesenchymal stromal cells induced local tolerance in rat renal ischemia/reperfusion injury11
Systematic review of controlled clinical studies using umbilical cord blood for regenerative therapy: Identifying barriers to assessing efficacy11
Isolation of embryonic stem cells from enhanced green fluorescent protein-transgenic mouse and their survival in the cochlea after allotransplantation11
Suppression of EBV release from irradiated B lymphoblastoid cell-lines: superior activity of ganciclovir compared with acyclovir11
CD19 chimeric antigen receptor–redirected T cells combined with epidermal growth factor receptor pathway substrate 8 peptide–derived dendritic cell vaccine in leukemia11
Human papilloma virus–specific T cells can be generated from naïve T cells for use as an immunotherapeutic strategy for immunocompromised patients11
Heterogeneity of in vitro–cultured CD34+ cells isolated from peripheral blood11
Early administration of tocilizumab (Toci) for the prevention of grade 4 cytokine release syndrome (CRS) after CD19-directed CAR T-cell therapy (CTL019)11
Progress and challenges in generating functional hematopoietic stem/progenitor cells from human pluripotent stem cells10
CD4+ bias in T cells cloned from a CML patient with active graft versus leukemia effect10
Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony–forming cells from peripheral blood and endothelial cells isolated from adipose tissue10
Automated Good Manufacturing Practice–compliant generation of human monocyte-derived dendritic cells from a complete apheresis product using a hollow-fiber bioreactor system overcomes a major hurdle i10
Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells10
Intrathecal cell therapy with autologous stromal cells increases cerebral glucose metabolism and can offer a new approach to the treatment of Alzheimer's type dementia10
Mesenchymal stromal cells from adipose tissue attached to suture material enhance the closure of enterocutaneous fistulas in a rat model10
Autologous bone marrow–derived CD133 cells with core decompression as a novel treatment method for femoral head osteonecrosis: a pilot study10
Removal process of prion and parvovirus from human platelet lysates used as clinical-grade supplement for ex vivo cell expansion10
Perspectives of the International Society for Cell & Gene Therapy Gastrointestinal Scientific Committee on the Intravenous Use of Mesenchymal Stromal Cells in Inflammatory Bowel Disease (PeMeGi)10
Optimization of methodology for production of CD25/CD71 allodepleted donor T cells for clinical use10
T-cell receptor gene-modified cells: past promises, present methodologies and future challenges10
Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues9
New method for the isolation of endothelial cells from large vessels9
Similar proteomic profiles of human mesenchymal stromal cells from different donors9
The use of unlicensed bone marrow–derived platelet lysate–expanded mesenchymal stromal cells in colitis: a pre-clinical study9
Streamlined production of genetically modified T cells with activation, transduction and expansion in closed-system G-Rex bioreactors9
The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility complex I-Streptamer isolation technolo9
Expansion of megakaryocyte progenitors from cryopreserved leukocyte concentrates of human placental and umbilical cord blood in short-term liquid culture9
Intravenous mesenchymal stromal cell therapy for inflammatory bowel disease: Lessons from the acute graft versus host disease experience9
TEMPORARY REMOVAL: CD271 identifies functional human hepatic stellate cells, which localize in peri-sinusoidal and portal areas in liver after partial hepatectomy9
Mesenchymal stromal cells protect human cardiomyocytes from amyloid fibril damage9
Low cytomegalovirus-specific T-cell counts at reactivation are associated with progression to high-level viremia or disease in seropositive recipients of hematopoietic cell grafts from seropositive bu9
Application of a clinical grade CD34-mediated method for the enrichment of microvascular endothelial cells from fat tissue9
Microporous acellular extracellular matrix combined with adipose-derived stem cell sheets as a promising tissue patch promoting articular cartilage regeneration and interface integration9
Evaluation of different routes of administration and biodistribution of human amnion epithelial cells in mice9
Except for C-C chemokine receptor 7 expression, monocyte-derived dendritic cells from patients with multiple sclerosis are functionally comparable to those of healthy controls8
Characteristic differences among osteogenic cell populations of rat bone marrow stromal cells isolated from untreated, hemolyzed or Ficoll-treated marrow8
Comparison of trophic factors secreted from human adipose-derived stromal vascular fraction with those from adipose-derived stromal/stem cells in the same individuals8
Bioactive factors secreted from mesenchymal stromal cells protect the intestines from experimental colitis in a three-dimensional culture8
Primitive AML progenitors from most CD34+ patients lack CD33 expression but progenitors from many CD34− AML patients express CD338
Human CD141+ dendritic cells generated from adult peripheral blood monocytes8
Natural killer cells differentiated in vitro from cord blood CD34 + cells are more advantageous for use as an immunotherapy than peripheral blood and cord blood natural killer cells8
A Monte Carlo framework for managing biological variability in manufacture of autologous cell therapy from mesenchymal stromal cells therapies8
Generation of mesenchymal stromal cells from HOXB4-expressing human embryonic stem cells8
Polyunsaturated fatty acids confer cryoresistance on megakaryocytes generated from cord blood and also enhance megakaryocyte production from cryopreserved cord blood cells8
T-cell therapies for T-cell lymphoma8
Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease8
Bone marrow mesenchymal stromal cell uptake extracellular vesicles from carbon tetrachloride-injured hepatocytes without differentiating into hepatocyte-like cells in a short period8
Enrichment of vascular endothelial growth factor secreting mesenchymal stromal cells enhances therapeutic angiogenesis in a mouse model of hind limb ischemia8
Isolation of a novel embryonic stem cell cord blood–derived population with in vitro hematopoietic capacity in the presence of Wharton's jelly–derived mesenchymal stromal cells8
Cell and gene therapy manufacturing capabilities in Australia and New Zealand8
Generation of Zika virus–specific T cells from seropositive and virus-naïve donors for potential use as an autologous or “off-the-shelf” immunotherapeutic8
A stromal-free, serum-free system to expand ex vivo hematopoietic stem cells from mobilized peripheral blood of patients with hematologic malignancies and healthy donors7
Ultrastructural and molecular analyzes of insulin-producing cells induced from human hepatoma cells7
Matched sibling donor-derived piggybac CAR19 T cells induce remission of relapsed/refractory CD19+ malignancy following haematopoietic stem cell transplant7
Critical testing and parameters for consideration when manufacturing and evaluating tumor–associated antigen-specific T cells7
Cryopreservation and thawing of hematopoietic stem cell CD34-induced apoptosis through caspase pathway activation: Key role of granulocytes7
Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction7
The effects of culture conditions on the functionality of efficiently obtained mesenchymal stromal cells from human cord blood7
Immunological properties of mononuclear cells from blood stem cell harvests following mobilization with erythropoietin + G-CSF in cancer patients7
Improved expansion of T cells in culture when isolated with an equipment-free, high-throughput, flow-through microfluidic module versus traditional density gradient centrifugation7
Validation of a semi automatic device to standardize quantification of Colony-Forming Unit (CFU) on hematopoietic stem cell products7
Bone marrow stem cells assuage radiation-induced damage in a murine model of distraction osteogenesis: A histomorphometric evaluation7
Conditioned media from mesenchymal stromal cells and periodontal ligament fibroblasts under cyclic stretch stimulation promote bone healing in mouse calvarial defects7
False positive endotoxin results in a DC product caused by (1→3)-β–d-glucans acquired from a sterilizing cellulose filter7
In vitro generation of dendritic cells derived from cryopreserved CD34+ cells mobilized into peripheral blood in lymphoma patients7
Biomarkers of bone healing induced by a regenerative approach based on expanded bone marrow–derived mesenchymal stromal cells7
Safety issues of peribulbar injection of umbilical cord mesenchymal stem cell (UC-MSC) in patients with retinitis pigmentosa7
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