International Journal of Biological Sciences

Article	Citations
mRNA vaccines for COVID-19: what, why and how	184
Regulation of exosome production and cargo sorting	174
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells	150
Immunotherapy in colorectal cancer: current achievements and future perspective	126
Interaction between Aβ and Tau in the Pathogenesis of Alzheimer's Disease	115
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer	113
Current advances in the development of SARS-CoV-2 vaccines	104
Ferroptosis-Related Long Non-Coding RNA signature predicts the prognosis of Head and neck squamous cell carcinoma	99
Dihydroartemisinin: A Potential Natural Anticancer Drug	92
Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation	83
Underlying the Mechanisms of Doxorubicin-Induced Acute Cardiotoxicity: Oxidative Stress and Cell Death	82
Long COVID and its Management	80
GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential	77
Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells	74
Artificial intelligence in the diagnosis of COVID-19: challenges and perspectives	73
VEGF/VEGFR-Targeted Therapy and Immunotherapy in Non-small Cell Lung Cancer: Targeting the Tumor Microenvironment	68
Attitudes toward COVID-19 vaccines in Chinese college students	66
Construction and applications of SARS-CoV-2 pseudoviruses: a mini review	64
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway	62
Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy	62
The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review	61
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway	59
LncRNA H19: A novel oncogene in multiple cancers	58
The role of RNA m5C modification in cancer metastasis	56
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression	56

A combination therapy of Phages and Antibiotics: Two is better than one	54
The role of CD4+FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment	53
Application of radiomics and machine learning in head and neck cancers	53
Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance	53
The Landscape Of Alpha Fetoprotein In Hepatocellular Carcinoma: Where Are We?	52
Integrated Machine Learning and Bioinformatic Analyses Constructed a Novel Stemness-Related Classifier to Predict Prognosis and Immunotherapy Responses for Hepatocellular Carcinoma Patients	50
Understanding the Effects of Gut Microbiota Dysbiosis on Nonalcoholic Fatty Liver Disease and the Possible Probiotics Role: Recent Updates	49
CD47/SIRPα pathway mediates cancer immune escape and immunotherapy	48
A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19	48
SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3	47
βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases	46
Ferroptosis in Cancer Progression: Role of Noncoding RNAs	45
Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid	44
Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation	44
The role of ubiquitination and deubiquitination in tumor invasion and metastasis	44
Smad3 Signatures in Renal Inflammation and Fibrosis	44
Development and application of therapeutic antibodies against COVID-19	44
Progress of Breast Cancer basic research in China	44
SARS-CoV-2 variants evolved during the early stage of the pandemic and effects of mutations on adaptation in Wuhan populations	43
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination	43
NEAT1 as a competing endogenous RNA in tumorigenesis of various cancers: Role, mechanism and therapeutic potential	43
CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers	43
A Positive Feedback Loop between Inactive VHL-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression	42
Biological characteristics of IL-6 and related intestinal diseases	42
Potential of exosomes as diagnostic biomarkers and therapeutic carriers for doxorubicin-induced cardiotoxicity	42
miR-223: An Effective Regulator of Immune Cell Differentiation and Inflammation	42
LncRNA FAM83A-AS1 facilitates tumor proliferation and the migration via the HIF-1α/ glycolysis axis in lung adenocarcinoma	42
Role of hydrogen sulfide donors in cancer development and progression	42
HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m6A-MYC expression	42
CAR-T Cell Therapy for Breast Cancer: From Basic Research to Clinical Application	40
MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease	40
Tight junctions and their regulation by non-coding RNAs	40
Renal cell carcinoma-derived exosomes deliver lncARSR to induce macrophage polarization and promote tumor progression via STAT3 pathway	40
Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway	39
A systematic review of Vaccine Breakthrough Infections by SARS-CoV-2 Delta Variant	39
Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway	39
A review of physiological and cellular mechanisms underlying fibrotic postoperative adhesion	39
Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells	39
Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment	38
Neuraminidase 1 deficiency attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory via AMPK-SIRT3 pathway in diabetic cardiomyopathy mice	38
CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway	38
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition	37
Targeted Inhibition of LPL/FABP4/CPT1 fatty acid metabolic axis can effectively prevent the progression of nonalcoholic steatohepatitis to liver cancer	36
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells	36
Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axis	36
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages	36
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression	36
Targeting Ferroptosis as a Novel Approach to Alleviate Aortic Dissection	36
RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway	35
The role of miR-320 in glucose and lipid metabolism disorder-associated diseases	35

Hexokinase 3 dysfunction promotes tumorigenesis and immune escape by upregulating monocyte/macrophage infiltration into the clear cell renal cell carcinoma microenvironment	35
Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8)	35
FTO-mediated autophagy promotes progression of clear cell renal cell carcinoma via regulating SIK2 mRNA stability	35
ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression	35
TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR	35
Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer	35
Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver	34
The advanced glycation end-products (AGEs)/ROS/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration	34
Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validati	34
Optimizing the dynamic zero-COVID policy in China	33
Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations	33
B.1.617.2 (Delta) Variant of SARS-CoV-2: features, transmission and potential strategies	33
Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease	33
The Emerging Roles of Autophagy-Related MicroRNAs in Cancer	33
Rutin attenuates Sorafenib-induced Chemoresistance and Autophagy in Hepatocellular Carcinoma by regulating BANCR/miRNA-590-5P/OLR1 Axis	33
Exosomal circRNAs as novel cancer biomarkers: Challenges and opportunities	33
CircHIPK3 regulates pulmonary fibrosis by facilitating glycolysis in miR-30a-3p/FOXK2-dependent manner	32
Review of Covid-19 vaccine clinical trials - A puzzle with missing pieces	32
TNF-α augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell	31
Peripheral Macrophage-derived Exosomes promote repair after Spinal Cord Injury by inducing Local Anti-inflammatory type Microglial Polarization via Increasing Autophagy	31
Cancer-associated fibroblasts-derived exosomal miR-3656 promotes the development and progression of esophageal squamous cell carcinoma via the ACAP2/PI3K-AKT signaling pathway	31
Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies	31
Progress of Gastric Cancer Surgery in the era of Precision Medicine	31
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival	31
The emerging function and clinical significance of circRNAs in Thyroid Cancer and Autoimmune Thyroid Diseases	31
Myokine Irisin promotes osteogenesis by activating BMP/SMAD signaling via αV integrin and regulates bone mass in mice	31
TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury	30
Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue	30
Emerging Mechanisms and Targeted Therapy of Ferroptosis in Neurological Diseases and Neuro-oncology	30
Long Noncoding RNA KCNQ1OT1 is a Prognostic Biomarker and mediates CD8+ T cell exhaustion by regulating CD155 Expression in Colorectal Cancer	30
SARS-CoV-2-induced Overexpression of miR-4485 Suppresses Osteogenic Differentiation and Impairs Fracture Healing	29
An Overview: The Diversified Role of Mitochondria in Cancer Metabolism	29
Clinical characteristics and analysis of risk factors for disease progression of COVID-19: A retrospective Cohort Study	29
Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway	29
Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types	29
Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer	29
Capivasertib restricts SARS-CoV-2 cellular entry: a potential clinical application for COVID-19	29
New insights into checkpoint inhibitor immunotherapy and its combined therapies in hepatocellular carcinoma: from mechanisms to clinical trials	29
Accelerated Bone Regeneration by Astragaloside IV through Stimulating the Coupling of Osteogenesis and Angiogenesis	28
Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo	28
The role of Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as m6A readers in cancer	28
The Effects and Mechanisms of Flavonoids on Cancer Prevention and Therapy: Focus on Gut Microbiota	28
Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers	28
COVID-19: systemic pathology and its implications for therapy	27
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling	27
Exosome-depleted MiR-148a-3p derived from Hepatic Stellate Cells Promotes Tumor Progression via ITGA5/PI3K/Akt Axis in Hepatocellular Carcinoma	27
The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation	27
Role of m6A modification in female infertility and reproductive system diseases	27
MicroRNA-370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis	27
Evaluation and characterization of HSPA5 (GRP78) expression profiles in normal individuals and cancer patients with COVID-19	26
miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway	26
Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation	26
Propionate alleviates myocardial ischemia-reperfusion injury aggravated by Angiotensin II dependent on caveolin-1/ACE2 axis through GPR41	26
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway	26
The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage	26
Development of a novel immune-related lncRNA signature as a prognostic classifier for endometrial carcinoma	26
Partial EMT in Squamous Cell Carcinoma: A Snapshot	26
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma	25
Cepharanthine inhibits hepatocellular carcinoma cell growth and proliferation by regulating amino acid metabolism and suppresses tumorigenesis in vivo	25
CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA	25
Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a	25
PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer	25
Long Non-Coding RNAs: Potential Biomarkers and Targets for Hepatocellular Carcinoma Therapy and Diagnosis	25
Extrachromosomal Circular DNAs: Origin, formation and emerging function in Cancer	25
Humoral and Cellular Immune Responses of COVID-19 vaccines against SARS-Cov-2 Omicron variant: a systemic review	25
Roles of microRNAs in inflammatory bowel disease	25
Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis	25
Lipid-induced S-palmitoylation as a Vital Regulator of Cell Signaling and Disease Development	25
Regulation of RNA N6-methyladenosine modification and its emerging roles in skeletal muscle development	25
NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway	24
The emerging roles of m6A modification in liver carcinogenesis	24
Trophoblast-derived Lactic Acid Orchestrates Decidual Macrophage Differentiation via SRC/LDHA Signaling in Early Pregnancy	24
Crucial roles of different RNA-binding hnRNP proteins in Stem Cells	24
Acyl-CoA synthetase long-chain 3-mediated fatty acid oxidation is required for TGFβ1-induced epithelial-mesenchymal transition and metastasis of colorectal carcinoma	24
The Role of Respiratory Microbiota in Lung Cancer	24
MYC dysfunction modulates stemness and tumorigenesis in breast cancer	24
Identification and Validation of a Prognostic Model Based on Three MVI-Related Genes in Hepatocellular Carcinoma	23
The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma	23
The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review	23
The role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer's disease	23

Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing	23
Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations	23
Application of phototherapeutic-based nanoparticles in colorectal cancer	23
Assessment of global asymptomatic SARS-CoV-2 infection and management practices from China	23
MGP promotes CD8+ T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer	23
Tandem CAR-T cells targeting FOLR1 and MSLN enhance the antitumor effects in ovarian cancer	23
Tumor-associated macrophage-derived chemokine CCL5 facilitates the progression and immunosuppressive tumor microenvironment of clear cell renal cell carcinoma	23
METTL3 promotes cell cycle progression via m6A/YTHDF1-dependent regulation of CDC25B translation	23
An Update on the Multifaceted Role of NF-kappaB in Endometriosis	22
Single-cell transcriptomics reveals heterogeneous progression and EGFR activation in pancreatic adenosquamous carcinoma	22
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy	22
C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system	22
Gut microbiome in gastrointestinal cancer: a friend or foe?	22
SUMOylation of IGF2BP2 promotes vasculogenic mimicry of glioma via regulating OIP5-AS1/miR-495-3p axis	22
The role of Fibrinogen-like proteins in Cancer	22
Biological and Physiochemical Methods of Biofilm Adhesion Resistance Control of Medical-Context Surface	22
Hydroxychloroquine/Chloroquine as Therapeutics for COVID-19: Truth under the Mystery	22
Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2	22
Regulation of Ferroptosis by Amino Acid Metabolism in Cancer	22
Homoharringtonine inhibited breast cancer cells growth via miR-18a-3p/AKT/mTOR signaling pathway	22
Genistein-3′-sodium sulfonate Attenuates Neuroinflammation in Stroke Rats by Down-Regulating Microglial M1 Polarization through α7nAChR-NF-κB Signaling Pathway	22
Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells	22
Theaflavin protects against oxalate calcium-induced kidney oxidative stress injury via upregulation of SIRT1	21
High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level	21
COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2	21
SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer	21
Rocaglamide promotes the infiltration and antitumor immunity of NK cells by activating cGAS-STING signaling in non-small cell lung cancer	21
Targeting HMGB1: An available Therapeutic Strategy for Breast Cancer Therapy	21
The association of Metabolic Syndrome and its Components with the Incidence and Survival of Colorectal Cancer: A Systematic Review and Meta-analysis	21
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy	21
COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2	21
Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor	21
Multi-omics Analysis of Ferroptosis Regulation Patterns and Characterization of Tumor Microenvironment in Patients with Oral Squamous Cell Carcinoma	21
The role of gut microbiota in T cell immunity and immune mediated disorders	21
The Role of IL-6 in Fibrotic Diseases: Molecular and Cellular Mechanisms	21
miR-340: A multifunctional role in human malignant diseases	21
Extracellular vesicles, the emerging mirrors of brain physiopathology	21
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer	21
ATM at the crossroads of reactive oxygen species and autophagy	21
Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo	21
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway	20
Cantharidin inhibits osteosarcoma proliferation and metastasis by directly targeting miR-214-3p/DKK3 axis to inactivate β-catenin nuclear translocation and LEF1 translation	20
GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients	20
Targeting Necroptosis: A Novel Therapeutic Option for Retinal Degenerative Diseases	20
Krebs Von den Lungen-6 as a predictive indicator for the risk of secondary pulmonary fibrosis and its reversibility in COVID-19 patients	20
MicroRNA-216b targets HK2 to potentiate autophagy and apoptosis of breast cancer cells via the mTOR signaling pathway	20
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer	20
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury	20
KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer	20
Novel Role of the SIRT1 in Endocrine and Metabolic Diseases	20
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer	20
DGCR5 is activated by PAX5 and promotes pancreatic cancer via targeting miR-3163/TOP2A and activating Wnt/β-catenin pathway	20
The Role of p38γ in Cancer: From review to outlook	20
Splicing factor SRSF2-centric gene regulation	20
MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension	19
Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury	19
Radiosensitizer EXO-miR-197-3p Inhibits Nasopharyngeal Carcinoma Progression and Radioresistance by Regulating the AKT/mTOR Axis and HSPA5-mediated Autophagy	19
The role of intestinal microbiota and its metabolites in intestinal and extraintestinal organ injury induced by intestinal ischemia reperfusion injury	19
Targeting Breast Cancer Stem Cells	19
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury	19
The role of DNA mismatch repair in immunotherapy of human cancer	19
NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity	19
O-GlcNAcylation of ZEB1 facilitated mesenchymal pancreatic cancer cell ferroptosis	19
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway	19
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages	19
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs	19
The interplay between m6A modification and non-coding RNA in cancer stemness modulation: mechanisms, signaling pathways, and clinical implications	19
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway	19
Phase separation in Cancer: From the Impacts and Mechanisms to Treatment potentials	18
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop	18
Paradoxical HBsAg and anti-HBs coexistence among Chronic HBV Infections: Causes and Consequences	18
Development and application of ribonucleic acid therapy strategies against COVID-19	18
CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD+/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and O	18
Downregulation of PPARα mediates FABP1 expression, contributing to IgA nephropathy by stimulating ferroptosis in human mesangial cells	18
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation	18
N6-methyladenosine (m6A) in pancreatic cancer: Regulatory mechanisms and future direction	18
Exosomes in atherosclerosis: Convergence on macrophages	18
Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS/HO-1/GPX4 axis	18
Emerging Significance and Therapeutic Potential of Extracellular vesicles	18
Death-associated protein kinase 1 mediates Aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in Alzheimer's disease	18
Post-Translational Modifications of PCNA in Control of DNA Synthesis and DNA Damage Tolerance-the Implications in Carcinogenesis	18
The Genetic Variant of SARS-CoV-2: Would it matter for Controlling the Devastating Pandemic?	18
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis	18
Natural tannins as anti-SARS-CoV-2 compounds	18
miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy	18
CircCCNB1 silencing acting as a miR-106b-5p sponge inhibited GPM6A expression to promote HCC progression by enhancing DYNC1I1 expression and activating the AKT/ERK signaling pathway	18
Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity	18
Extracellular Vesicle-Mediated Secretion of HLA-E by Trophoblasts Maintains Pregnancy by Regulating the Metabolism of Decidual NK Cells	18
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca2+-FOXO1 pathway	18
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma	18
Celastrol ameliorates vascular neointimal hyperplasia through Wnt5a-involved autophagy	17
Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway	17
MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types	17
Emerging Piezo1 signaling in inflammation and atherosclerosis; a potential therapeutic target	17
Berberine improves insulin-induced diabetic retinopathy through exclusively suppressing Akt/mTOR-mediated HIF-1α/VEGF activation in retina endothelial cells	17