OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Biological Sciences is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells	218
mRNA vaccines for COVID-19: what, why and how	213
Regulation of exosome production and cargo sorting	210
Interaction between Aβ and Tau in the Pathogenesis of Alzheimer's Disease	192
Immunotherapy in colorectal cancer: current achievements and future perspective	171
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer	148
Underlying the Mechanisms of Doxorubicin-Induced Acute Cardiotoxicity: Oxidative Stress and Cell Death	140
Long COVID and its Management	122
Dihydroartemisinin: A Potential Natural Anticancer Drug	122
Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation	121
Neutrophil extracellular traps mediate m⁶A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells	119
GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential	113
Current advances in the development of SARS-CoV-2 vaccines	113
Ferroptosis-Related Long Non-Coding RNA signature predicts the prognosis of Head and neck squamous cell carcinoma	107
VEGF/VEGFR-Targeted Therapy and Immunotherapy in Non-small Cell Lung Cancer: Targeting the Tumor Microenvironment	90
Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance	86
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway	83
Artificial intelligence in the diagnosis of COVID-19: challenges and perspectives	81
The Landscape Of Alpha Fetoprotein In Hepatocellular Carcinoma: Where Are We?	79
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression	78
Construction and applications of SARS-CoV-2 pseudoviruses: a mini review	78
The role of RNA m⁵C modification in cancer metastasis	77
The role of ubiquitination and deubiquitination in tumor invasion and metastasis	77
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages	77
Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy	76

The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review	76
CD47/SIRPα pathway mediates cancer immune escape and immunotherapy	73
LncRNA H19: A novel oncogene in multiple cancers	72
Smad3 Signatures in Renal Inflammation and Fibrosis	70
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway	69
A Positive Feedback Loop between Inactive VHL-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression	69
Integrated Machine Learning and Bioinformatic Analyses Constructed a Novel Stemness-Related Classifier to Predict Prognosis and Immunotherapy Responses for Hepatocellular Carcinoma Patients	69
Attitudes toward COVID-19 vaccines in Chinese college students	68
Ferroptosis in Cancer Progression: Role of Noncoding RNAs	67
A combination therapy of Phages and Antibiotics: Two is better than one	67
Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway	66
Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation	64
An Overview: The Diversified Role of Mitochondria in Cancer Metabolism	63
Application of radiomics and machine learning in head and neck cancers	62
Understanding the Effects of Gut Microbiota Dysbiosis on Nonalcoholic Fatty Liver Disease and the Possible Probiotics Role: Recent Updates	61
HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m⁶A-MYC expression	61
Mitophagy alleviates cisplatin-induced renal tubular epithelial cell ferroptosis through ROS/HO-1/GPX4 axis	59
miR-223: An Effective Regulator of Immune Cell Differentiation and Inflammation	59
CAR-T Cell Therapy for Breast Cancer: From Basic Research to Clinical Application	57
LncRNA FAM83A-AS1 facilitates tumor proliferation and the migration via the HIF-1α/ glycolysis axis in lung adenocarcinoma	56
Progress of Breast Cancer basic research in China	56
The role of CD4⁺FoxP3⁺ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment	56
Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment	55
Targeting Ferroptosis as a Novel Approach to Alleviate Aortic Dissection	55
A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19	54
ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression	53
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination	53
Role of hydrogen sulfide donors in cancer development and progression	53
Renal cell carcinoma-derived exosomes deliver lncARSR to induce macrophage polarization and promote tumor progression via STAT3 pathway	52
NEAT1 as a competing endogenous RNA in tumorigenesis of various cancers: Role, mechanism and therapeutic potential	52
TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury	52
Biological characteristics of IL-6 and related intestinal diseases	52
PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer	51
The advanced glycation end-products (AGEs)/ROS/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration	51
βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases	51
SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3	51
Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells	51
Tight junctions and their regulation by non-coding RNAs	50
Potential of exosomes as diagnostic biomarkers and therapeutic carriers for doxorubicin-induced cardiotoxicity	50
Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway	49
Development and application of therapeutic antibodies against COVID-19	49
A review of physiological and cellular mechanisms underlying fibrotic postoperative adhesion	49
CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway	48
Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8)	48
Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid	48
MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease	48
CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers	48
TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR	47
FTO-mediated autophagy promotes progression of clear cell renal cell carcinoma via regulating SIK2 mRNA stability	47
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition	47

Neuraminidase 1 deficiency attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory via AMPK-SIRT3 pathway in diabetic cardiomyopathy mice	46
Targeted Inhibition of LPL/FABP4/CPT1 fatty acid metabolic axis can effectively prevent the progression of nonalcoholic steatohepatitis to liver cancer	46
A systematic review of Vaccine Breakthrough Infections by SARS-CoV-2 Delta Variant	45
Progress of Gastric Cancer Surgery in the era of Precision Medicine	45
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression	45
SARS-CoV-2 variants evolved during the early stage of the pandemic and effects of mutations on adaptation in Wuhan populations	44
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells	44
Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axis	44
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway	43
Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver	43
Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types	43
Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies	42
Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validati	42
CircHIPK3 regulates pulmonary fibrosis by facilitating glycolysis in miR-30a-3p/FOXK2-dependent manner	42
Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer	42
Myokine Irisin promotes osteogenesis by activating BMP/SMAD signaling via αV integrin and regulates bone mass in mice	41
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival	41
Hexokinase 3 dysfunction promotes tumorigenesis and immune escape by upregulating monocyte/macrophage infiltration into the clear cell renal cell carcinoma microenvironment	41
The crosstalk between ferroptosis and mitochondrial dynamic regulatory networks	40
Cancer-associated fibroblasts-derived exosomal miR-3656 promotes the development and progression of esophageal squamous cell carcinoma via the ACAP2/PI3K-AKT signaling pathway	40
The Emerging Roles of Autophagy-Related MicroRNAs in Cancer	40
Optimizing the dynamic zero-COVID policy in China	40
The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation	39
Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease	39
Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a	39
The role of gut microbiota in T cell immunity and immune mediated disorders	38
B.1.617.2 (Delta) Variant of SARS-CoV-2: features, transmission and potential strategies	38
Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo	38
Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway	38
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation	38
Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo	38
RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway	38
The role of Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as m⁶A readers in cancer	38
TNF-α augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell	37
Rutin attenuates Sorafenib-induced Chemoresistance and Autophagy in Hepatocellular Carcinoma by regulating BANCR/miRNA-590-5P/OLR1 Axis	37
Exosomal circRNAs as novel cancer biomarkers: Challenges and opportunities	37
Targeting Breast Cancer Stem Cells	37
Accelerated Bone Regeneration by Astragaloside IV through Stimulating the Coupling of Osteogenesis and Angiogenesis	37
Role of m6A modification in female infertility and reproductive system diseases	36
Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue	36
The role of miR-320 in glucose and lipid metabolism disorder-associated diseases	36
Acyl-CoA synthetase long-chain 3-mediated fatty acid oxidation is required for TGFβ1-induced epithelial-mesenchymal transition and metastasis of colorectal carcinoma	36
MGP promotes CD8⁺ T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer	36
Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers	35
Gut microbiome in gastrointestinal cancer: a friend or foe?	35
Emerging Mechanisms and Targeted Therapy of Ferroptosis in Neurological Diseases and Neuro-oncology	35
NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway	35
Novel Role of the SIRT1 in Endocrine and Metabolic Diseases	35
Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations	35
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma	35
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling	35
Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation	35
The role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer's disease	35
Regulation of Ferroptosis by Amino Acid Metabolism in Cancer	35
Long Noncoding RNA KCNQ1OT1 is a Prognostic Biomarker and mediates CD8⁺ T cell exhaustion by regulating CD155 Expression in Colorectal Cancer	35
The Role of IL-6 in Fibrotic Diseases: Molecular and Cellular Mechanisms	35
The Effects and Mechanisms of Flavonoids on Cancer Prevention and Therapy: Focus on Gut Microbiota	35
New insights into checkpoint inhibitor immunotherapy and its combined therapies in hepatocellular carcinoma: from mechanisms to clinical trials	35
The emerging function and clinical significance of circRNAs in Thyroid Cancer and Autoimmune Thyroid Diseases	34
SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer	34
Tumor-associated macrophage-derived chemokine CCL5 facilitates the progression and immunosuppressive tumor microenvironment of clear cell renal cell carcinoma	34
Cepharanthine inhibits hepatocellular carcinoma cell growth and proliferation by regulating amino acid metabolism and suppresses tumorigenesis in vivo	33
Review of Covid-19 vaccine clinical trials - A puzzle with missing pieces	33
Peripheral Macrophage-derived Exosomes promote repair after Spinal Cord Injury by inducing Local Anti-inflammatory type Microglial Polarization via Increasing Autophagy	33
Roles of microRNAs in inflammatory bowel disease	33
SARS-CoV-2-induced Overexpression of miR-4485 Suppresses Osteogenic Differentiation and Impairs Fracture Healing	33
MicroRNA-370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis	33
Partial EMT in Squamous Cell Carcinoma: A Snapshot	33
Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer	33
Exosome-depleted MiR-148a-3p derived from Hepatic Stellate Cells Promotes Tumor Progression via ITGA5/PI3K/Akt Axis in Hepatocellular Carcinoma	33
GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients	33
Clinical characteristics and analysis of risk factors for disease progression of COVID-19: A retrospective Cohort Study	32
COVID-19: systemic pathology and its implications for therapy	32
Exosomes and Their Bioengineering Strategies in the Cutaneous Wound Healing and Related Complications: Current Knowledge and Future Perspectives	32
Capivasertib restricts SARS-CoV-2 cellular entry: a potential clinical application for COVID-19	32
Molecular Mechanisms of Mitochondrial Quality Control in Ischemic Cardiomyopathy	32
Tandem CAR-T cells targeting FOLR1 and MSLN enhance the antitumor effects in ovarian cancer	32
Genistein-3′-sodium sulfonate Attenuates Neuroinflammation in Stroke Rats by Down-Regulating Microglial M1 Polarization through α7nAChR-NF-κB Signaling Pathway	32
Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance	31
Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity	31

Propionate alleviates myocardial ischemia-reperfusion injury aggravated by Angiotensin II dependent on caveolin-1/ACE2 axis through GPR41	31
The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage	31
Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations	31
Biological and Physiochemical Methods of Biofilm Adhesion Resistance Control of Medical-Context Surface	31
The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma	30
The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review	30
Lipid-induced S-palmitoylation as a Vital Regulator of Cell Signaling and Disease Development	30
An Update on the Multifaceted Role of NF-kappaB in Endometriosis	30
The association of Metabolic Syndrome and its Components with the Incidence and Survival of Colorectal Cancer: A Systematic Review and Meta-analysis	30
Extrachromosomal Circular DNAs: Origin, formation and emerging function in Cancer	30
Regulation of RNA N⁶-methyladenosine modification and its emerging roles in skeletal muscle development	30
Mouse models of nonalcoholic fatty liver disease (NAFLD): pathomechanisms and pharmacotherapies	30
miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway	30
Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2	30
Theaflavin protects against oxalate calcium-induced kidney oxidative stress injury via upregulation of SIRT1	29
Trophoblast-derived Lactic Acid Orchestrates Decidual Macrophage Differentiation via SRC/LDHA Signaling in Early Pregnancy	29
The role of DNA mismatch repair in immunotherapy of human cancer	29
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing	29
Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis	29
Single-cell transcriptomics reveals heterogeneous progression and EGFR activation in pancreatic adenosquamous carcinoma	28
The role of Fibrinogen-like proteins in Cancer	28
Humoral and Cellular Immune Responses of COVID-19 vaccines against SARS-Cov-2 Omicron variant: a systemic review	28
Long Non-Coding RNAs: Potential Biomarkers and Targets for Hepatocellular Carcinoma Therapy and Diagnosis	28
CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA	28
Extracellular vesicles, the emerging mirrors of brain physiopathology	28
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway	28
Crucial roles of different RNA-binding hnRNP proteins in Stem Cells	28
Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells	28
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs	28
The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways	28
PROX1 promotes breast cancer invasion and metastasis through WNT/β-catenin pathway via interacting with hnRNPK	28
Homoharringtonine inhibited breast cancer cells growth via miR-18a-3p/AKT/mTOR signaling pathway	28
METTL3 promotes cell cycle progression via m⁶A/YTHDF1-dependent regulation of CDC25B translation	28
KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer	28
ATM at the crossroads of reactive oxygen species and autophagy	27
Natural tannins as anti-SARS-CoV-2 compounds	27
MYC dysfunction modulates stemness and tumorigenesis in breast cancer	27
Development of a novel immune-related lncRNA signature as a prognostic classifier for endometrial carcinoma	27
Krebs Von den Lungen-6 as a predictive indicator for the risk of secondary pulmonary fibrosis and its reversibility in COVID-19 patients	27
Downregulation of PPARα mediates FABP1 expression, contributing to IgA nephropathy by stimulating ferroptosis in human mesangial cells	27
Identification and Validation of a Prognostic Model Based on Three MVI-Related Genes in Hepatocellular Carcinoma	27
Flap endonuclease 1 Facilitated Hepatocellular Carcinoma Progression by Enhancing USP7/MDM2-mediated P53 Inactivation	27
Targeting HMGB1: An available Therapeutic Strategy for Breast Cancer Therapy	27
Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma	27
Curcumin and its Analogs and Carriers: Potential Therapeutic Strategies for Human Osteosarcoma	27
Berberine improves insulin-induced diabetic retinopathy through exclusively suppressing Akt/mTOR-mediated HIF-1α/VEGF activation in retina endothelial cells	27
CXCL12-CXCR4/CXCR7 Axis in Cancer: from Mechanisms to Clinical Applications	27
Rocaglamide promotes the infiltration and antitumor immunity of NK cells by activating cGAS-STING signaling in non-small cell lung cancer	27
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer	27
Evaluation and characterization of HSPA5 (GRP78) expression profiles in normal individuals and cancer patients with COVID-19	27
Application of phototherapeutic-based nanoparticles in colorectal cancer	27
SUMOylation of IGF2BP2 promotes vasculogenic mimicry of glioma via regulating OIP5-AS1/miR-495-3p axis	27
Emerging Piezo1 signaling in inflammation and atherosclerosis; a potential therapeutic target	27
Multi-omics Analysis of Ferroptosis Regulation Patterns and Characterization of Tumor Microenvironment in Patients with Oral Squamous Cell Carcinoma	26
COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2	26
Neutrophil Extracellular Traps Delay Diabetic Wound Healing by Inducing Endothelial-to-Mesenchymal Transition via the Hippo pathway	26
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer	26
MicroRNA-216b targets HK2 to potentiate autophagy and apoptosis of breast cancer cells via the mTOR signaling pathway	26
CXCR4-dependent macrophage-to-fibroblast signaling contributes to cardiac diastolic dysfunction in heart failure with preserved ejection fraction	26
miR-340: A multifunctional role in human malignant diseases	26
Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor	26
The emerging roles of m⁶A modification in liver carcinogenesis	26
High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level	26
Hydroxychloroquine/Chloroquine as Therapeutics for COVID-19: Truth under the Mystery	26
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway	26
The Role of Respiratory Microbiota in Lung Cancer	25
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop	25
Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury	25
Targeting Necroptosis: A Novel Therapeutic Option for Retinal Degenerative Diseases	25
Extracellular Vesicle-Mediated Secretion of HLA-E by Trophoblasts Maintains Pregnancy by Regulating the Metabolism of Decidual NK Cells	25
Mitochondrial quality control in diabetic cardiomyopathy: from molecular mechanisms to therapeutic strategies	25
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages	25
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy	25
Emerging roles of protein palmitoylation and its modifying enzymes in cancer cell signal transduction and cancer therapy	25
The role of intestinal microbiota and its metabolites in intestinal and extraintestinal organ injury induced by intestinal ischemia reperfusion injury	25
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury	25
Cantharidin inhibits osteosarcoma proliferation and metastasis by directly targeting miR-214-3p/DKK3 axis to inactivate β-catenin nuclear translocation and LEF1 translation	25
Assessment of global asymptomatic SARS-CoV-2 infection and management practices from China	25
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma	25
Phase separation in Cancer: From the Impacts and Mechanisms to Treatment potentials	24
The progress of multimodal imaging combination and subregion based radiomics research of cancers	24
Paradoxical HBsAg and anti-HBs coexistence among Chronic HBV Infections: Causes and Consequences	24
COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2	24
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca²⁺-FOXO1 pathway	24
HIF-1α/YAP Signaling Rewrites Glucose/Iodine Metabolism Program to Promote Papillary Thyroid Cancer Progression	24
The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers	24
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy	24
HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation	24
MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension	24
DGCR5 is activated by PAX5 and promotes pancreatic cancer via targeting miR-3163/TOP2A and activating Wnt/β-catenin pathway	24
The interplay between m6A modification and non-coding RNA in cancer stemness modulation: mechanisms, signaling pathways, and clinical implications	24
Post-Translational Modifications of PCNA in Control of DNA Synthesis and DNA Damage Tolerance-the Implications in Carcinogenesis	24
Covalent Inhibition of Pyruvate Kinase M2 Reprograms Metabolic and Inflammatory Pathways in Hepatic Macrophages against Non-alcoholic Fatty Liver Disease	23
C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system	23
Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway	23